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RefludanThis page contains recent news articles, when available, and an overview of Refludan but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Refludan (when available) Used to break up clots and to reduce thrombocytopenia. Hirudin binds to thrombin and prevents thrombus or clot formation. Hirudin is a highly potent, selective, and essentially irreversible inhibitor of thrombin and clot-bond thrombin. Hirudin requires no cofactor for its anticoagulant action. For treatment of heparin-induced thrombocytopenia Mechanism Of Action: Hirudin forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen and initiate the clotting cascade. News Articles on Lepirudin Revised Refludan Prescribing Information - Nov 15, 2006 The FDA has revised the prescribing information for Refludan (lepirudin) to include information for use in patients scheduled for transition to oral ... Facts and Comparisons Alvorlige allergiske reaksjoner: Økt risiko ved gjentatt behandling - Oct 20, 2007 Refludan (lepirudin) «Schering AG» er en rekombinant hirudinanalog. ... Refludan brukes hos pasienter med heparinassosiert trombocytopeni type II (HATtype ... Statens legemiddelverk Pharmion Corp - Jun 19, 2006 ...and Refludan should account for $16 million in ... The four products are Innohep, Refludan, Thalidomide and Vidaza. The company intends to continue to ... $35.00 - Stock Reports - Standard & Poor's Stroke Secondary to Syphilis Medications - Stroke Secondary to... - Apr 17, 2008 New forms include argatroban (Novastan), bivalirudin (Angiomax), danaparoid (Orgaran), lepirudin (Refludan), and desirudin (Revasc). ... New York Times Stroke Secondary to Atherosclerosis - Feb 20, 2007 New forms include argatroban (Novastan), bivalirudin (Angiomax), danaparoid (Orgaran), lepirudin (Refludan), and desirudin (Revasc). ... New York Times Hemorrhagic Stroke Medications - Hemorrhagic Stroke Health Information... - Sep 16, 2008 New forms include argatroban (Novastan), bivalirudin (Angiomax), danaparoid (Orgaran), lepirudin (Refludan), and desirudin (Revasc). ... New York Times Stroke Related to Cocaine Use - Feb 13, 2008 New forms include argatroban (Novastan), bivalirudin (Angiomax), danaparoid (Orgaran), lepirudin (Refludan), and desirudin (Revasc). ... New York Times Article: Merck Drops New Parkison's Disease Drug - AP Online | … - Jun 23, 2006 Article: Schering AG: Pharmion Obtains Rights to Refludan ... Canadian Corporate News; June 5 ... Refludan, acquired by Schering AG from Aventis late last . ... Pay-Per-View - AP Online - HighBeam Research Study hammers last nail in the coffin for Bayer's Trasylol - May 15, 2008 BART Trial data results, the company would not return to actively promoting Trayslol in the United States and discontinue the promotion of Refludan." Medical Marketing & Media - Medical Marketing and Media Analysis of Pharmion Corp. - Feb 23, 2007 The firm's other marketed products are thrombosis medications Innohep and Refludan. It has also netted the rights to commercialize Satraplatin, ... Free with registration - M2 Presswire - AccessMyLibrary.com Heart Attack Treatment - Heart Attack Health Information - NY Times … - Jul 15, 2008 Direct thrombin inhibitors, such as argatroban (Novastan), danaparoid (Orgaran), lepirudin (Refludan), and bivalirudin (Angiomax). A clear benefit for these ... New York Times Beware of heparin-induced thrombocytopenia.(and its care and treatment... - Mar 21, 2005 Rice pointed out that two direct thrombin inhibitors (DTIs), argatroban (Encysive Pharmaceuticals/GlaxoSmithKline) and lepirudin (Refludan, Berlex), ... Free with registration - Drug Topics - AccessMyLibrary.com The Heparin Paradox - Feb 28, 2005 Drugs used as alternatives to heparin include lepirudin (Refludan) and Argatroban (see table, next page). Both drugs are direct thrombin inhibitors and ... Nurse Week Pharmion Corporation 2006 Investor/Analyst Meeting - Part 1. - Nov 2, 2006 But we use these, all right, Refludan and Innohep, to build our commercial infrastructure in first to EU and then in the United States. ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com CEO: Pharmion Has Evolved, Could 'Transform' During '07 - Jan 11, 2007 It markets Innohep (tinzaparin), a low-molecular-weight heparin approved in the US for deep-vein thrombosis, as well as Refludan (lepirudin), ... BioWorld Online - BioWorld Online Pharmion Announces Q4 Sales of $51.5 Million; 2004 Sales of $130.2 … - Feb 15, 2005 Cost of sales for 2003 included inventory charges, primarily related to Refludan, totaling $2.1 million, which reduced the gross margin by eight percentage ... $4.95 - PR Newswire - ECNext Article: Prasco pact.(Prasco Laboratories has signed a distribution... - Aug 29, 2005 M2 PRESSWIRE-19 May 2000-Aventis Pharmaceuticals: Aventis Pharmaceuticals receives letter from FDA on Refludan ... RDATE:18052000 PARSIPPANY ... Pay-Per-View - Chain Drug Review - HighBeam Research Baxter Heparin Issues Could Boost Sales of Alternative Blood Thinners - Feb 21, 2008 Direct thrombin inhibitors such as Angiomax from Medicines Co., Refludan from Bayer AG, and Argotroban from GlaxoSmithKline could be used in some situations ... Newsinferno.com Bellwether Report.comFollowing Pharmion Corp. - Sep 25, 2006 The firm's other marketed products are thrombosis medications Innohep and Refludan. Pharmion acquires licenses to complete development and market its ... $4.95 - M2 Presswire - ECNext Press Release: Analysis of Pharmion Corp. - M2 Presswire | HighBeam … - Feb 23, 2007 The firm's other marketed products are thrombosis medications Innohep and Refludan. It has also netted the rights to commercialize Satraplatin, ... Pay-Per-View - M2 Presswire - HighBeam Research One-year experience with the platelet glycoprotein IIb/IIIa antagonist... - Jun 1, 2008 Immediately after surgery, thrombosis prophylaxis with r-hirudin (Refludan; Aventis Pharma, Frankfurt, Germany) to a target activated partial thromboplastin ... The Journal of Thoracic and Cardiovascul... Article: Popular allergy medicine in Mylan Inc.'s sights: Lawsuit... - Apr 13, 2006 M2 PRESSWIRE-19 May 2000-Aventis Pharmaceuticals: Aventis Pharmaceuticals receives letter from FDA on Refludan ... RDATE:18052000 PARSIPPANY ... Pay-Per-View - Dominion Post - HighBeam Research Press Release: Pharmion to Present at the 2006 Bank of America Health... - May 11, 2006 Pharmion sells Refludan (lepirudin ... Schering AG, of Berlin. Pharmion also features a late-stage ... Concurrent with its offering, Pharmion extended a ... Pay-Per-View - PR Newswire - HighBeam Research Competitors by Product Report - Mar 8, 2008 Bayer AG (ADR) (BAYRY) Products:. Berlex Refludan (Lepirudin). Bristol Myers Squibb Co. (BMY) Products:. Coumadin (Warfarin Sodium) ... $75.00 - Revere Reports - Revere Merger and Acquisition Scenario - Feb 24, 2006 Berlex Betapace/Betapace AF (Sotalol Hydrochloride); Berlex Betaseron (Interferon Beta-1b); Berlex AGT-MI (FGF-4 Gene Therapy); Berlex Refludan (Lepirudin) ... $250.00 - Revere Reports - Revere Outpatient management of anticoagulation therapy.(Drug overview)( … - Apr 1, 2007 Hirudin, lepirudin (Refludan), bivalirudin (Angiomax), desirudin (Ipravask), argatroban (Acova), and ximelagatran (Exanta; not available in United States) ... Free with registration - American Family Physician - AccessMyLibrary.com Merger and Acquisition Scenario - Mar 11, 2006 Berlex Betapace/Betapace AF (Sotalol Hydrochloride); Berlex Betaseron (Interferon Beta-1b); Berlex AGT-MI (FGF-4 Gene Therapy); Berlex Refludan (Lepirudin) ... $250.00 - Revere Reports - Revere EDITED BRIEF - May 8, 2008 Not included in non-GAAP revenue are product sales from Innohep and Refludan whose disposition is. currently under evaluation. D. Margin: ... $54.00 - Thomson StreetEvents - Alacra Store Merger and Acquisition Scenario - May 13, 2006 Berlex Betapace/Betapace AF (Sotalol Hydrochloride); Berlex Betaseron (Interferon Beta-1b); Berlex AGT-MI (FGF-4 Gene Therapy); Berlex Refludan (Lepirudin) ... $250.00 - Revere Reports - Revere FINAL TRANSCRIPT - May 8, 2008 Innohep and Refludan, whose disposition is currently under evaluation. Our gross product margin for the first quarter was approximately 90%, as compared to ... $54.00 - Thomson StreetEvents - Alacra Store Merger and Acquisition Scenario - Mar 11, 2006 Berlex Betapace/Betapace AF (Sotalol Hydrochloride); Berlex Betaseron (Interferon Beta-1b); Berlex AGT-MI (FGF-4 Gene Therapy); Berlex Refludan (Lepirudin) ... $250.00 - Revere Reports - Revere Outpatient management of anticoagulation therapy.(Drug overview)( … - Apr 1, 2007 Hirudin, lepirudin (Refludan), bivalirudin (Angiomax), desirudin (Ipravask), argatroban (Acova), and ximelagatran (Exanta; not available in United States) ... $4.95 - American Family Physician - ECNext Merger and Acquisition Scenario - Apr 15, 2006 Berlex Betapace/Betapace AF (Sotalol Hydrochloride); Berlex Betaseron (Interferon Beta-1b); Berlex AGT-MI (FGF-4 Gene Therapy); Berlex Refludan (Lepirudin) ... $250.00 - Revere Reports - Revere Press Release: Bellwether Report.com is Observing Pharmion Corp. - M2... - Oct 12, 2006 The firm's other marketed products are thrombosis medications Innohep and Refludan. It has also netted the rights to commercialize Satraplatin, ... Pay-Per-View - M2 Presswire - HighBeam Research Drug/Medical Device - Sep 30, 2006 Berlex Refludan (Lepirudin), Anticoagulation In Patients With Heparin-Induced Thrombocytopenia And Associated Thromboembolic Disease, Bleeding From Puncture ... $70.00 - Revere Reports - Revere Merger and Acquisition Scenario - Mar 11, 2006 Berlex Betapace/Betapace AF (Sotalol Hydrochloride); Berlex Betaseron (Interferon Beta-1b); Berlex AGT-MI (FGF-4 Gene Therapy); Berlex Refludan (Lepirudin) ... $250.00 - Revere Reports - Revere Press Release: Bellwether Report.comFollowing Pharmion Corp. - M2 … - Sep 25, 2006 The firm's other marketed products are thrombosis medications Innohep and Refludan. Pharmion acquires licenses to complete development and market its ... Pay-Per-View - M2 Presswire - HighBeam Research Merger and Acquisition Scenario - Mar 11, 2006 Berlex Betapace/Betapace AF (Sotalol Hydrochloride); Berlex Betaseron (Interferon Beta-1b); Berlex AGT-MI (FGF-4 Gene Therapy); Berlex Refludan (Lepirudin) ... $250.00 - Revere Reports - Revere Étude rétrospective de l'utilisation du danaparoïde sodique aux... - Jan 6, 2006 Plusieurs alternatives ont été approuvées dans cette indication incluant des inhibiteurs directs de la thrombine, tels que la lépirudine (Refludan ® ) et ... john-libbey-eurotext.fr Press Release: Pharmion to Present at the UBS Global Life Sciences … - Sep 22, 2005 Article: Ferghana Partners Advised Schering AG On Refludan(TM) Transaction ... PR Newswire; June 6, 2002 ; 700+ words ... ... exclusive agreement with ... Pay-Per-View - PR Newswire - HighBeam Research Article: Blacks have worse outcomes after ACS.(acute coronary... - Jan 1, 2006 Article: Hoechst Marion Roussel Submits Refludan(R) For Approval of New ... PR Newswire; July 14, 1999 ; 700+ words ... ... of Building Global Brands KANSAS ... Pay-Per-View - Internal Medicine News - HighBeam Research Article: US stocks rise on moderating economic data - AP Worldstream... - Apr 13, 2006 Article: Schering AG Acquires Refludan(R) From Aventis. PR Newswire; October 1, 2001 ; 700+ words ... ... Berlex Laboratories." "Schering AG is committed to ... Pay-Per-View - AP Worldstream - HighBeam Research Press Release: Schering AG, Germany Announces Results of Two … - Jul 31, 2006 Article: Schering AG: Pharmion Obtains Rights to Refludan ... Canadian Corporate News; June 5, 2002 ; 700+ words ... ... agreement with Schering AG (FSE:SCH ... Pay-Per-View - PR Newswire - HighBeam Research Brand Names/Synonyms: Refludan is also known by the following brand names and/or synonymsHirudin variant-1;Lepirudin; Refludan (Berlex Labs) Drug Category: Refludan is categorized under the following by the FDA: Anticoagulants; Antithrombotic Agents; unclassified therapeutic agents (92:00.00) Dosage Forms: POWDER FOR SOLUTION Absorption: Not Available Interactions: Not Available Chemical IUPAC Name: Hirudo medicinalis hirudin (variant 1) |
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