Repaglinide

This page contains recent news articles, when available, and an overview of Repaglinide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Repaglinide
(when available)

Pharmacology and use:
Repaglinide is an oral blood glucose-lowering drug of the meglitinide class used in the management of type 2 diabetes mellitus (also known as non-insulin dependent diabetes mellitus or NIDDM). Repaglinide lowers blood glucose levels by stimulating the release of insulin from the pancreas. This action is dependent upon functioning beta cells in the pancreatic islets. Insulin release is glucose-dependent and diminishes at low glucose concentrations. For the treatment of Type II diabetes mellitus

Mechanism Of Action:
Repaglinide closes ATP-dependent potassium channels in the b-cell membrane by binding at characterizable sites. This potassium channel blockade depolarizes the b-cell, which leads to an opening of calcium channels. The resulting increased calcium influx induces insulin secretion. The ion channel mechanism is highly tissue selective with low affinity for heart and skeletal muscle.

News Articles on Repaglinide

Better weight control with metformin and insulin  -  ‎Nov 11, 2009‎
However, weight gain was less with metformin plus insulin than with repaglinide plus insulin (difference in mean body weight between treatments –2.51 kg). ... Endochrinology Update

FDA Safety Changes: DepoDur, Neoral, Lexiva  -  ‎Nov 4, 2009‎
Cyclosporine may increase the plasma concentrations of repaglinide and thereby increase the risk for hypoglycemia, the FDA warned. Repaglinide appears to be ... Medscape

Modern insulins drive up Novo Nordisk earnings  -  ‎Oct 29, 2009‎
Human insulins slipped 2% to 2.48 billion kroner and oral antidiabetic products, notably NovoNorm/Prandin (repaglinide), were down 3% to 650 million kroner. ... Pharma Times

Cyclosporine markedly raises the plasma concentrations of repaglinide...  -  May 27, 2005
Background and Objective: Repaglinide is an antidiabetic drug metabolized by ... At 9 AM on day 2, they ingested a single 0.25-mg dose of repaglinide. ... Nature.com

Caraco Pharma gets tentative FDA nod for generic Prandin  -  Aug 13, 2007
The generic version, Repaglinide, is indicated to lower the blood glucose in patients with type 2 diabetes mellitus, whose high blood-sugar levels cannot be ... Reuters

Sciele signs exclusive marketing agreement with Novo Nordisk; ups...  -  Nov 19, 2007
US to other Novo Nordisk (nyse: NVO - news - people ) products containing repaglinide,' which is the active ingredient in both Prandin and PrandiMet. ... Forbes

Expanded EU diabetes drug application withdrawn  -  Oct 16, 2006
NovoNorm (repaglinide) and Prandin (repaglinide) have both received regulatory approval previously in the EU to be used in combination with exercise and ... Hays Pharma

Telithromycin, but not montelukast, increases the plasma concentration...  -  Aug 4, 2005
Background and Objective: The antidiabetic repaglinide is metabolized by cytochrome P450 ... On day 3, they ingested a single 0.25-mg dose of repaglinide. ... Nature.com

Cholestatic Hepatitis Associated With Repaglinide  -  Mar 16, 2005
Repaglinide is a fast, short-acting meglitinide analog antidiabetic drug approved for the treatment of type 2 diabetes. Hypoglycemia is a major adverse ... RedOrbit

Learn about Repaglinide from Consumer Reports Health.  -  Jan 5, 2007
Repaglinide is used to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar ... consumerreports.org

Novo Nordisk A/S - Regulatory Approval  -  Jun 24, 2008
It is the first fixed-dose combination of repaglinide, a fast-acting insulin secretagogue, and metformin, an insulin sensitiser. ... marketwire.com

… With Type 2 Diabetes Achieve QoF HbA1c Targets With Repaglinide...  -  Aug 31, 2008
Repaglinide has a distinct mode of action that helps control HbA1c by ... An analysis of the repaglinide and metformin treatment from 2005/6 found that only ... Medical News Today - Medical News Today (press release)

… Endogenous Insulin Production by Repaglinide Stimulation of C- …  -  Jun 14, 2005
C-peptide stimulation test a practical diagnostic method to determine the presence of endogenous insulin production, and eliminating guesswork about when ... Diabetes In Control

… With Type 2 Diabetes Achieve QoF HbA1c Targets With Repaglinide...  -  Jul 20, 2008
Repaglinide has a distinct mode of action that helps control HbA1c by ... An analysis of the repaglinide and metformin treatment from 2005/6 found that only ... Medical News Today - Medical News Today (press release)

FDA Approved Generic Prandin  -  Aug 15, 2007
FDA has granted tentative approval for Caraco Pharmaceutical Laboratories' Abbreviated New Drug Application (ANDA) for Repaglinide Tablets USP (repaglinide) ... emaxhealth.com

Generic name: Repaglinide  -  Dec 1, 2005
Prandin is used to reduce blood sugar levels in people with type 2 diabetes (the kind that does not require insulin shots). It's prescribed when diet and ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Diabetes Therapy; Researchers' findings advance diabetes therapy …  -  Feb 1, 2005
Study 2: The combination of repaglinide and metformin enhanced early- and ... Repaglinide increased early and late phases of insulin responses in HC, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Diabetes Therapy; Findings advance knowledge in diabetes therapy …  -  Mar 7, 2006
Study 3: Repaglinide reduces oxidative stress in the tissues of diabetic rabbits. "In this study, the anti-oxidative properties of repaglinide were examined ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Diabetes Therapy; Researchers' findings advance diabetes therapy …  -  Feb 4, 2005
Study 2: The combination of repaglinide and metformin enhanced early- and ... Repaglinide increased early and late phases of insulin responses in HC, ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Repaglinide, í?¡ìˆ˜ ì‹ ì†?…ì‹?후•공복시 저혈당 발현 낮아  -  Sep 29, 2007
KATP channel� 뇌, 심장근육, 혈관�활근�� 존재하는� 뇌� SUR 아단위는 췌장 베타세�와 ��한 반면(SUR-1), 심장근육�나 혈관�활근� SUR 아단위는 �� ... 디지틀보사

Press Release: Novo Nordisk Inc. Announces Exclusive Agreement With …  -  Nov 19, 2007
PrandiMet(R) is a combination tablet of repaglinide and metformin, which has yet to be ... Sciele will also market PrandiMet (repaglinide/metformin). ... Pay-Per-View - PR Newswire - HighBeam Research

Inhibitory and Inductive Effects of Rifampin on the Pharmacokinetics...  -  Oct 4, 2006
It had previously been shown that rifampin reduced the exposure to repaglinide by 50% when repaglinide was simultaneously administered with rifampin, ... Nature.com

Diabetes Diagnosis; Potential beta-cell imaging agent synthesized  -  Jan 1, 2005
..."In vitro testing of the nonradioactive methoxy-repaglinide was performed to characterize the affinity for binding to the human SUR1 isoform," said Bjorn ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Older agents for type 2 diabetes equal or superior to newer agents...  -  Oct 1, 2007
Treatment with TZDs and treatment with repaglinide was associated with weight ... Treatment with second-generation sulfonylureas and with repaglinide was ... Free with registration - Formulary - AccessMyLibrary.com

Understanding Hypoglycemia  -  Jul 25, 2006
Nateglinide and repaglinide are taken with meals and act for only a short time. The risk of hypoglycemia is lower than for sulfonylureas, but it is still ... Diabetes Self Management

Emerging Evidence of the Impact of Kidney Disease on Drug Metabolism ...  -  Jan 7, 2008
For instance, the meglitinide hypoglycemic drug repaglinide undergoes hepatic ... 15 These data suggest that hepatic clearance of repaglinide, mediated by ... Nature.com

Prandin Offers Advantages in Elderly Diabetics  -  Aug 15, 2006
..."The major clinical implication of our study," said Dr. Francesco Purrello, "is that short-acting hypoglycemic drugs, such as repaglinide, should be used in ... Diabetes In Control

Press Release: Caraco Pharmaceutical Laboratories, Ltd. Announces …  -  Aug 13, 2007
Repaglinide is indicated as an adjunct to diet and exercise to lower the blood ... We believe we have a first to file position on Repaglinide, which could ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Good glucose control.(DIABETES Update)(Brief Article) -...  -  Nov 1, 2005
...of the American Diabetes Association June 23, 2001, showed repaglinide ... because they suggest blood glucose control can be improved with repaglinide . ... Pay-Per-View - Saturday Evening Post - HighBeam Research

Analysis of diabetes drugs  -  Jul 17, 2007
Glimepiride, glipizide, glyburide, and repaglinide are associated with hypoglycemia (when blood glucose levels go too low) more than other diabetes drugs. ... News-Medical.net

While Most Diabetes Drugs Provide Similar Glucose Control, Some Offer...  -  Jul 23, 2007
Glimepiride, glipizide, glyburide, and repaglinide are associated with hypoglycemia (when blood glucose levels go too low) more than other diabetes drugs. ... emaxhealth.com

Article: Should PCOS be treated with insulin sensitizers or oral …  -  Feb 15, 2006
Article: Prandin(R) (Repaglinide) Approved for New Indication: Combination ... ... Repaglinide stimulates insulin release from the pancreas; ... Pay-Per-View - OB GYN News - HighBeam Research

Most Diabetes Drugs Provide Similar Glucose Control  -  Jul 13, 2007
Glimepiride, glipizide, glyburide, and repaglinide are associated with hypoglycemia (when blood glucose levels go too low) more than other diabetes drugs. ... newswise.com

Press Release: Liraglutide Phase 2 Study Shows Increased Insulin …  -  Jun 13, 2006
Article: Repaglinide Has Unique Mechanism Of Action.(Prandin stimulates ... Drug Week; July 27, 2001 ; 700+ words ... ... repaglinide stimulates insulin ... Pay-Per-View - PR Newswire - HighBeam Research

Sciele Expects to Launch Six Products in 2008; Reaffirms Revenue and ...  -  Jan 9, 2008
Prandin[R] (repaglinide) for type II diabetes, and, upon FDA approval, PrandiMet[R] (repaglinide/metformin) also for type II diabetes; ... Free with registration - Business Wire - AccessMyLibrary.com

Drug to help diabetics during Ramzan  -  Sep 20, 2005
According to the doctors, drugs like Repaglinide and Natiglinide, short acting ... Repaglinide and Natiglinide are short duration drugs that will help bring ... Times of India

Clinical news: Combination regimen benefits in diabetes.(Brief...  -  Apr 14, 2007
A combination of repaglinide, metformin and bedtime neutral protamine hagedorn ... The group taking repaglinide, metformin and NPH insulin were on only 58.1 ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

Press Release: Metabolex Initiates Phase 2/3 Trial of Metaglidasen in...  -  Jun 10, 2006
Article: Prandin(R) (Repaglinide) Approved for New Indication: Combination ... ... Repaglinide stimulates insulin release from the pancreas; ... Pay-Per-View - PR Newswire - HighBeam Research

Nordisk and Sciele sign marketing deal.  -  Nov 26, 2007
The agreement also transfers marketing rights to Nordisk's PrandiMet (repaglinide plus metformin), which is currently in development and is yet to be ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Generic diabetes drugs  -  Sep 8, 2008
Neither repaglinide (Prandin) nor nateglinide (Starlix) (both of which spur the pancreas to release more insulin quickly after meals) has a generic form. ... Diabetes Self Management

For Type 2 Diabetes, Older Drugs Seem Tried and True  -  Jul 16, 2007
..."Sulfonylureas and repaglinide were associated with greater risk for hypoglycemia, thiazolidinediones with greater risk for heart failure, and metformin ... MedPage Today

Article: 2 adult diabetes drugs appear safe in children.(Metabolic …  -  Aug 1, 2005
Article: Repaglinide (Prandin(R)) Shows Greater Improvement in Blood ... PR Newswire; June 26, 2003 ; 700+ words ... ... escalation with metformin (to 1000 ... Pay-Per-View - Family Practice News - HighBeam Research

Company Profile Report  -  Oct 4, 2008
PrandiMet (Repaglinide/Metformin Fixed Combo) ... Prandin (Repaglinide). Intermediary Metabolism Disorders. Hypercholesterolemia ... $50.00 - Revere Reports - Revere

Do sulfonylurea drugs increase the risk of cardiac events?( …  -  Jan 17, 2006
Of the meglitinides, it is unlikely that repaglinide, a benzoic acid derivative with a shorter period of attachment to the ATP-sensitive potassium channels, ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

Press Release: Metabolex Announces Presentation of Metaglidasen …  -  Sep 8, 2005
Article: Prandin(R) (Repaglinide) Approved for New Indication: Combination ... ... Repaglinide stimulates insulin release from the pancreas; ... Pay-Per-View - PR Newswire - HighBeam Research

Company Profile Report  -  Oct 4, 2008
MetPrandin (Repaglinide/Metformin Fixed Combo) ... Prandin (Repaglinide). Intermediary Metabolism Disorders. Hypercholesterolemia ... $50.00 - Revere - Alacra Store

Healthcare Republic - Search results for Diabetes  -  Nov 30, 2006
Daiichi Sankyo has acquired the sales and marketing rights for repaglinide in the UK. Repaglinide w... Read more. Click on a filter below to refine your ... Healthcare Republic - Healthcare Republic

Press Release: New Data From Head-to-Head Phase 3 Trial Demonstrate …  -  Oct 17, 2008
PRNewswire/ -- Novo Nordisk A/S (NYSE: NVO ... promote Prandin(TM) (repaglinide) and Novo Nordisk's full range of ... strategic needs. ... Pay-Per-View - PR Newswire - HighBeam Research

{beta}-Cell Insulin Secretory Response to Oral Hypoglycemic Agents Is...  -  Mar 1, 2006
There was a marked decrease in the dextrose infusion rate with administration of either repaglinide or glipizide at hypoglycemia compared with drug ... Journal of Clinical Endocrinology and...

Press Release: Schering-Plough Highlights PEGINTRON(TM) and …  -  Apr 17, 2008
PR Newswire; June 23, 2001 ; 700+ words ... ... repaglinide is effective in combination therapy.2,3 Repaglinide is currently approved for combination ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Metatarsalgia (or Forefoot Pain) Affects Millions of …  -  Apr 18, 2008
Article: Research Showing Prandin(R) (repaglinide) Tablet Improved ... ... Article: MULTINATIONAL STUDY SHOWS NOVONORM (REPAGLINIDE) IMPROVES ... ... Pay-Per-View - PR Newswire - HighBeam Research

Kinetics-Effect Relations of Insulin-Releasing Drugs in Patients With...  -  Jan 23, 2005
This fostered development of meglitinide analogs, such as nateglinide and repaglinide, which are clinically effective insulin-releasing drugs. ... RedOrbit

Loislaw Federal District Court Opinions - NOVO NORDISK v. CARACO …  -  Sep 20, 2006
The claims in the `358 patent require the drug repaglinide, which is marketed by Plaintiffs. Defendant Caraco is a Michigan corporation that filed an ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Prescribing for Diabetes  -  Oct 8, 2005
For some patients, the insulin secretagogues nateglinide and repaglinide may be required. If there is intolerance to all of these, there may be a place for ... RedOrbit

Pharmacy update - Drugs used in type 2 diabetes.  -  Feb 24, 2007
At the time of writing, repaglinide and nateglinide are licensed for use as combination therapy with metformin, and repaglinide is also licensed for use as ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

Novo: Øget dødelighed hos intensivt behandlede diabetikere  -  Jun 26, 2008
Novo Nordisks to diabetestabletter Prandin og Prandimet indeholder ikke glitazoner, men derimod repaglinide (Prandin) og repaglinide blandet med metformin ... UgensErhverv

Older type 2 drugs are as effective as newer ones.(Metabolic Disorders...  -  Sep 15, 2007
Weight gains ranging from 1 to 5 kg were seen with most other oral diabetes medications: thiazolidinediones, repaglinide, and second-generation ... Pay-Per-View - Family Practice News - HighBeam Research

Diabete di tipo 2: le sulfoniluree aumentano il rischio di eventi...  -  Apr 4, 2006
Tra le meglitinidi, è improbabile che la Repaglinide, un derivato ... Quando la Repaglinide è stata confrontata con la Gliburide durante gli studi clinici ... XagenaSalute

알파글루코시ë?°ì?´ì¦ˆ, ì‹?후 혈당 완만 억제  -  May 4, 2006
...국내�서 사용 가능한 약물로는 Repaglinide와 Nateglinide가 있다<표 2>. △ Repaglinide(Prandin, Novonorm) = 베타세�� ATP - �존성 칼륨 통로�서 설�요소제와 ... bosa.co.kr

ì?¸ìŠ?린분비촉진제ì?˜ 새로운 ê³ ì°°  -  Nov 3, 2005
...그러나 glibenclamide, glimepiride, meglitinide, repaglinide� 경우�는 ... Repaglinide는 benzamido moiety만 갖고 있으나 소수성� 매우 강해 1곳�서만 결합 ... 메디칼트리뷴

Danish shares close slightly lower, Carlsberg higher UPDATE  -  Aug 14, 2007
US based Caraco Pharmaceutical Laboratories said it has gained tentative FDA approval for repaglinide, a generic version of the Danish group's diabetes ... Forbes

Article: Gastric bypass reduces [HbA.sub.1c] levels in diabetes.(News)...  -  Aug 1, 2008
Article: Focus on repaglinide: An oral hypoglycemic agent ... ... Repaglinide (Prandin, Novo Nordisk Pharmaceuticals, Inc), the most recently FDA-approved ... Pay-Per-View - Internal Medicine News - HighBeam Research

Confronto fra i vari farmaci antidiabetici  -  Jul 18, 2007
I glitazoni, la metformina e la repaglinide portano ad un controllo glicemico paragonabile a quello ottenuto con le sulfoniluree di seconda generazione: con ... Pillole.org

Older Diabetes Drug Sometimes the Best Choice  -  Jul 16, 2007
Another drug, repaglinide, was linked to less-serious forms of hypoglycemia in the elderly and people who skip meals. Slutsky said the newer drugs are ... Washington Post

Danish shares flat midmorning, William Demant higher  -  Aug 14, 2007
US-based Caraco Pharmaceutical Laboratories said it has gained tentative FDA approval for repaglinide, a generic version of the Danish group's diabetes ... Forbes

Article: Gastric bypass lowers Hb[A.sub.1c] levels in type 2.(Metaboli...  -  Aug 15, 2008
Article: Focus on repaglinide: An oral hypoglycemic agent ... ... Repaglinide (Prandin, Novo Nordisk Pharmaceuticals, Inc), the most recently FDA-approved ... Pay-Per-View - Family Practice News - HighBeam Research

In the News; Heart failure risk prompts warning labels on diabetes...  -  Aug 1, 2007
Drugs in this class include nateglinide (Starlix) and repaglinide (Prandin). Slows the absorption of glucose by blocking enzymes that break it down in the ... Free with registration - Harvard Women's Health Watch - AccessMyLibrary.com

Press Release: Metabolex's Investigational Treatment for Type 2...  -  Mar 22, 2005
PR Newswire; June 23, 2001 ; 700+ words ... ... repaglinide in combination ... Article: Prandin(R) (Repaglinide) Approved for New Indication: Combination . ... Pay-Per-View - PR Newswire - HighBeam Research

Severe iatrogenic hypoglycemia in type 2 diabetes mellitus  -  Mar 2, 2006
Hypoglycemia occurs in patients with T2DM treated with insulin or with an insulin secretagogue, such as a sulfonylurea, repaglinide or nateglinide. ... Nature.com

A case of recurrent gastrointestinal bleeding and protein-losing …  -  Sep 21, 2006
...omeprazole (40 mg daily), digoxin (0.1 mg daily), and repaglinide (0.5 mg three times a day before meals) for his type 2 diabetes. ... Nature.com

Newer drugs queried for type 2 diabetes  -  Jul 25, 2007
While they found little difference in glycaemic control between the various drugs, sulfonylureas and repaglinide were associated with greater risk for ... 6minutes

REGIONAL NEWS: MICROSOFT HIRES FORMER STAPLES …  -  Jan 23, 2008
1997 ; 700+ words ... ... the Food and Drug Administration recommended yesterday that Novo Nordisk's repaglinide be approved to treat Type II diabetes. ... Pay-Per-View - Seattle Post-Intelligencer - HighBeam Research

Article: DRUG CAPSULE; WHAT YOU SHOULD KNOW - The Milwaukee …  -  Jan 9, 2006
Prandin (repaglinide) What it does: Prandin is an oral agent used to treat type 2 diabetes. It's in a class of drugs k... Pay-Per-View - Milwaukee Journal Sentinel - HighBeam Research

Medication as last resort | Article from New Straits Times | HighBeam...  -  Nov 26, 2006
Examples of drugs in this class are repaglinide and nateglinide. (The report on possible effectiveness of the latter for the prevention of diabetes and ... Pay-Per-View - New Straits Times - HighBeam Research

Novo slÃ¥r igen i patentstrid  -  Aug 14, 2007
...en ANDA-ansøgning, en ansøgning om godkendelse af generisk medicin, til de amerikanske sundhedsmyndigheder FDA, der dækkede det aktive stof Repaglinide. ... Børsen Online

Postprandial Hyperglycemia  -  Jun 13, 2006
Repaglinide (Prandin) and nateglinide (Starlix) stimulate the pancreas to release insulin in a glucose-dependent fashion. (That is, the more glucose there ... Diabetes Self Management

Step 8: Drugs and insulin  -  May 1, 2006
Examples are glyburide, glipizide, glimepiride and repaglinide. These drugs:. Most people want to avoid taking insulin to control their diabetes. ... Waco Tribune-Herald - Waco Tribune Herald

Comparison of Top 10 Diabetes Drugs Finds Older is Better  -  Jul 25, 2007
In addition to metformin, the thiazolidinediones and sulfonylureas, drugs included in their analysis were repaglinide (Prandin), miglitol (Glyset), ... SeniorJournal.com

Sulfonylureas :: Diabetes Self-Management  -  Jun 16, 2006
Repaglinide (Prandin), a member of another class of beta-cell stimulating drugs called meglitinides, acts in response to rises in blood glucose levels ... Diabetes Self Management

Study: Older Diabetes Drugs Safe to Use  -  Jul 18, 2007
..._Glimepiride, glipizide, glyburide and repaglinide lead to too-low blood sugar more often than other drugs do. _Metformin and acarbose more often cause ... go.com

Torrent Signs agreement with Tasly to market Cardio-tonic Pill  -  Oct 11, 2006
The Company was the first to launch global blockbusters like Atenolol, Rosiglitazone and Repaglinide in India and enjoys market leadership in many brands in ... Equity Bulls

Oral Medicines for Type 2 Diabetes  -  Jul 18, 2006
Taking a missed dose of repaglinide or nateglinide between meals could result in hypoglycemia because these drugs stimulate the release of insulin from the ... Diabetes Self Management

Diabetes in later life.  -  Jan 19, 2006
Insulin secretagogues These agents include sulphonylureas and the rapid-acting insulin secretagogues repaglinide and nataglinide. ... Free with registration - Update - AccessMyLibrary.com

Independent Nurse: Clinical - Prescribing - Oral therapy options for...  -  Sep 30, 2005
Nateglinide and repaglinide are post-prandial glucose regulators (PPGRs).(8) They act by stimulating first-phase insulin secretion, which occurs immediately ... Free with registration - GP - AccessMyLibrary.com

Treatments and devices for future diabetes management.  -  May 3, 2005
The two approved for use in the UK are repaglinide, which is indicated for use as monotherapy, and nateglinide, which is indicated for use in oral ... Nursing Times

Older Is Better: Top Ten Comparison Of Diabetes Drugs Give Metformin ...  -  Jul 29, 2007
In addition to metformin, the thiazolidinediones and sulfonylureas, drugs included in their analysis were repaglinide (Prandin), miglitol (Glyset), ... sciencedaily.com

Insulin Resistance  -  May 17, 2006
...glipizide (Glucotrol, Glucotrol XL), glimepiride (Amaryl), and repaglinide (Prandin), lower blood glucose levels by boosting insulin secretion. ... Diabetes Self Management

New diabetic drug class shows promise  -  Mar 24, 2005
There are only two commercially available meglitinides: NovoNordisk's Repaglinide (Prandin) and Novartis' Nateglinide (Starlix). ... DrugResearcher.com

ADA type 2 diabetes goals still not being met.(Metabolic Disorders)( …  -  Jul 15, 2005
...and 16% nonsulfonylurea secretagogues (8% repaglinide and 8% nateglinide). Of these, monotherapy was used in 25%, two glucose-lowering drugs in 41%, ... Free with registration - Family Practice News - AccessMyLibrary.com

Glimepiride in the medical management of Type 2 diabetes  -  Oct 23, 2005
...thiazolidinediones (pioglitazone and rosiglitazone), meglitinide analogues (repaglinide), amino acid D-phenylalanine derivatives (nateglinide), ... MedIndia

Biocon to launch MAb in SEA markets  -  Feb 22, 2007
...nateglinide, a novel drug designed to prevent postprandial hyperglycemia, pioglitazone for type II diabetes to repaglinide, a fast-acting, short-acting ... pharmabiz.com

The American Heart Association now recommends that patients should …  -  Jul 15, 2006
Meglitinides (repaglinide, nateglinide). Stimulate insulin secretion. These newer drugs are better than sulfonylureas in controlling glucose spikes after ... HealthCentral.com

Oral Medicines for Type 2 Diabetes  -  Jul 18, 2006
There is one meglitinide on the market, repaglinide (Prandin), and one d-phenylalanine derivative, nateglinide (Starlix). These drugs are not sulfonylureas, ... Diabetes Self Management

Diabex XR - Metformine hydrochloride - Medical Drug  -  Oct 4, 2008
These include other classes of antihyperglycaemic agents such as sulfonylureas and repaglinide, anti-hypertensive drugs such as beta-blockers, ... Virtual Medical Centre - The Virtual Medical Centre

Oral Agent Combination Therapy  -  Jun 14, 2005
...nateglinide or repaglinide -- in variable dose based on meal size and exercise in a manner similar to that used with variable prandial insulin dosing. ... Medscape

PulseClinical: Need to know Diabetes.  -  Nov 16, 2006
There is a niche market for the insulin secretagogues repaglinide and nateglinide. Their rapid action may be of value in people with high postprandial peaks ... Free with registration - Pulse - AccessMyLibrary.com

What Is the Role of Rosiglitazone in Steroid-Induced Diabetes?  -  Mar 8, 2007
If postprandial hyperglycemia is the predominant concern, a short-acting insulin secretagogue (eg, nateglinide or repaglinide) may be sufficient. ... Medscape

Medications scheduled to come off patent in 2007 *.(Drug and Formulary...  -  Feb 1, 2007
Perindopril Aceon Not available Repaglinide Prandin Not available Ropinirole Requip Not available Sibutramine Mericlia Not available Sumatriptan Imitrex ... Free with registration - Formulary - AccessMyLibrary.com

A New Face in The Crowd: FGF-21  -  Jun 21, 2005
Sulfonylurea drugs like glyburide and glipizide are examples of the former category, as are newer agents like repaglinide (Prandinâ„¢) and nateglinide ... Diabetes In Control

UM study: Economic rebound starts next year  -  Aug 20, 2007
Laboratories Ltd. announced on Monday that the US Food and Drug Administration granted it tentative approval of a new drug application for Repaglinide, ... Crain's Detroit Business

FDA panel recommends expanded diabetes drug testing  -  Jul 10, 2008
A regimen in which there was more use of repaglinide, rosiglitazone, insulin and/or alpha glucosidase inhibitor showed increased mortality risk in the ... Endocrine Today

Diabetes mellitus drugs in India  -  Nov 21, 2007
There are two molecules available in this group ie Repaglinide and Nateglinide. These drugs are absorbed more rapidly and attained its peak plasma level ... pharmabiz.com

Type-2 diabetes 'better treated' by cheap drugs.(Brief article)  -  Jul 20, 2007
HbA1c was lowered by around 1 percentage point by metformin, sulphonylureas, thiazolidinediones and repaglinide. A slightly weaker effect on glycaemic ... Free with registration - GP - AccessMyLibrary.com

Brand Names/Synonyms:
Repaglinide is also known by the following brand names and/or synonymsAG-EE 388 ZW; AG-EE 623 ZW; Prandin; Repaglinida [Inn-Spanish]; Repaglinide; Repaglinide [Usan]; Repaglinidum [Inn-Latin]

Drug Category:
Repaglinide is categorized under the following by the FDA: Hypoglycemic Agents; Meglitinides; ATC:A10BX02

Dosage Forms:
TABLET

Absorption:
Rapid (bioavailability is 56%)

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
2-ethoxy-4-[[3-methyl-1-[2-(1-piperidyl)phenyl]-butyl]carbamoylmethyl]benzoicacid





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy