Rescriptor

This page contains recent news articles, when available, and an overview of Rescriptor but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Rescriptor
(when available)

Pharmacology and use:
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (nNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Delavirdine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by causing a disruption of the enzyme's catalytic site. The activity of Delavirdine does not compete with template or nucleoside triphosphates. HIV-2 RT and eukaryotic DNA polymerases (such as human DNA polymerases alpha, beta, or sigma) are not inhibited by Delavirdine. For the treatment of HIV-1 infection in combination with appropriate antiretroviral agents when therapy is warranted

Mechanism Of Action:
Delavirdine binds directly to viral reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by disrupting the enzyme's catalytic site.

News Articles on Delavirdine

New tool helps predict possible drug side-effects  -  ‎Nov 13, 2009‎
This tool revealed that one side effect of the AIDS drug rescriptor causes severe rashes by inadvertently targeting a hormone receptor known as histamine H4 ... MinnPost.com

GlaxoSmithKline-Pfizer launch HIV joint venture  -  ‎Nov 4, 2009‎
In addition, ViiV has Rescriptor, a non-nucleoside reverse transcriptase inhibitor (NNRTI) available only in the US; originally a Pharmacia product, ... Pharmafocus

Glaxo und Pfizer gründen Joint Venture  -  ‎Nov 3, 2009‎
Von Pfizer kommt das Celsentri sowie die nur in den USA zugelassenen Produkte Viracept und Rescriptor. Nach Angaben von ViiB Healthcare generierten die ... apotheke-adhoc

AIDS group bans Pfizer sales reps  -  Feb 8, 2007
Pfizer also sells the HIV drugs Viracept and Rescriptor. ... Calls to obtain sales figures for Viracept and Rescriptor were not immediately returned. ... ABCmoney.co.uk

Ã?ndice de lecciones  -  Mar 1, 2008
Rescriptor es un medicamento anti-VIH que pertenece a la categoría de los ... Rescriptor impide que el VIH ingrese al núcleo de las células T sanas. ... AIDSmeds.com HIV/AIDS Treatment News

Which Are The Easiest Drug Combinations? (A Look At Fewer Pills and …  -  Aug 17, 2007
The development of the 200mg tablets (Rescriptor was only available in larger, 100mg dissolvable tablets when it was first approved) has made Rescriptor ... AIDSmeds.com HIV/AIDS Treatment News

Etravirine—Countdown to Launch  -  Jan 15, 2008
Though they both have their unique set of side effects, overall they are considered to be safe; Rescriptor (delavirdine) is less frequently used, ... AIDSmeds.com HIV/AIDS Treatment News

Press Release: Schering-Plough Presents Vicriviroc Clinical Study …  -  Feb 10, 2006
Article: Preliminary Study Results Show Use of RESCRIPTOR(R) with ... PR Newswire; February 3, 1999 ; 700+ words ... ... of the quadruple therapy ... Pay-Per-View - PR Newswire - HighBeam Research

Solutions for an upset stomach.(HIV AND TRAVEL)(Brief Article) |...  -  Nov 8, 2005
Alka-Seltzer, Maalox, Tums, and Rolaids can interfere with the stomach's absorption of Agenerase, Crixivan, Rescriptor, and Reyataz, while Axid, Pepcid, ... Pay-Per-View - The Advocate - HighBeam Research

Do treatments work differently in women than in men?  -  Feb 25, 2008
For example, the amount of the non-nucleoside reverse transcriptase inhibitor Rescriptor® (delavirdine) is often higher in the blood of women than in men. ... AIDSmeds.com HIV/AIDS Treatment News

Solutions for an upset stomach.(HIV AND TRAVEL)(Brief Article)  -  Nov 8, 2005
Alka-Seltzer, Maalox, Tums, and Rolaids can interfere with the stomach's absorption of Agenerase, Crixivan, Rescriptor, and Reyataz, while Axid, Pepcid, ... $4.95 - The Advocate - ECNext

The search for an HIV/AIDS vaccine  -  Nov 30, 2006
By 1991, other (non-nucleoside analog) reverse transcriptase inhibitors, drugs like Viramune, Rescriptor and Sustiva, had been introduced that attacked the ... Gay and Lesbian Times

Invirase (saquinavir, SQV)  -  Mar 1, 2008
Un tercer INNTR, Rescriptor (delavirdine), aumenta significativamente la cantidad ... Si se usa Rescriptor, la dosis de Invirase debe disminuirse a cuatro ... AIDSmeds.com HIV/AIDS Treatment News

Press Release: FDA Approves First Ever Treatment for Hepatitis C in …  -  Feb 26, 2005
Article: RESCRIPTOR(R)-Containing Combination Therapy May Be ... PR Newswire; September 8, 2000 ; 700+ words ... ... durability of anti-HIV therapy ... Pay-Per-View - PR Newswire - HighBeam Research

Article: US pushes to limit generic drug rightsAgreements seek to...  -  Apr 19, 2006
...response ... freeze the price of its two AIDS drugs, Viracept and Rescriptor ... or no health insurance for AIDS drugs are facing budgetary shortfalls . ... Pay-Per-View - International Herald Tribune - HighBeam Research

Dynamic Duo Etravirine and Prezista Shine in Studies  -  Jul 6, 2007
...has significant antiviral activity in patients with documented resistance to "first generation" NNRTIs (eg, Sustiva, Viramune, and Rescriptor). ... AIDSmeds.com HIV/AIDS Treatment News

NATIONAL BRIEFS | Article from The Record (Bergen County, NJ) | …  -  Feb 9, 2007
Pfizer, the world's largest drug maker, sells two HIV products, Rescriptor and Viracept, and is seeking U.S. regulatory approval for a third. ... Pay-Per-View - The Record - HighBeam Research

Medicijnmarkt / Apotheker laveert tussen industrie en arme patiënt  -  Jun 29, 2006
Want natuurlijk had Ida veel liever dan de nu aangeboden aidsremmer 'rescriptor' het patent gehad op een middel dat wel op de lijst van essentiële middelen ... Trouw

Tibotec's Intelence (Etravirine, TMC125) is Approved by FDA  -  Jan 18, 2008
Compared with older NNRTIs—efavirenz (found in Sustiva/Stocrin and Atripla), nevirapine (Viramune) and delavirdine (Rescriptor)—test tube studies suggest ... AIDSmeds.com HIV/AIDS Treatment News

Amprenavir (Systemic).  -  Jul 28, 2005
Delavirdine (eg, Rescriptor) -- Use with amprenavir may lead to a possible resistance to delavirdine. They should not be administered together. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

How to take Ziprasidone from Consumer Reports Health.  -  Jan 4, 2007
...delavirdine (Rescriptor); diltiazem (Cardizem, Dilacor, Tiazac, others); diuretics ('water pills');dopamine agonists such as bromocriptine (Parlodel), ... consumerreports.org

Anti-HIV drug from rainforest almost lost before its discovery  -  Sep 13, 2005
Approved NNRTIs include Viramune® (nevirapine) from Boehringer Ingelheim, Sustiva® (efavirenz) from Bristol-Myers Squibb, and Rescriptor® (delavirdine) from ... Mongabay.com

Rifampin (Systemic).(Drug overview)  -  Aug 1, 2006
...or Chloramphenicol or Corticosteroids (cortisone-like medicine) or Delavirdine (eg, Rescriptor) or Digitalis glycosides (heart medicine) or Disopyramide ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Mayo Clinic expertise  -  Aug 9, 2008
Four NNRTIs are approved for clinical use: nevirapine (Viramune), delavirdine (Rescriptor), efavirenz (Sustiva) and etravirine (Intelence). ... MayoClinic.com

Videx.(Drug overview)  -  Dec 1, 2005
If you've been prescribed the HIV drugs Crixivan or Rescriptor, allow 1 hour to pass before taking Videx. When taking antibiotics known as quinolones, ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

How to take Fluticasone Oral Inhalation from Consumer Reports Health.  -  Jan 3, 2007
...cimetidine (Tagamet); clarithromycin (Biaxin); cyclosporine (Neoral, Sandimmune); danazol (Danocrine); delavirdine (Rescriptor); diltiazem (Cardizem, ... consumerreports.org

How to take Pimecrolimus Topical from Consumer Reports Health.  -  Jan 7, 2006
...cyclosporine (Neoral, Sandimmune); danazol (Danocrine); delavirdine (Rescriptor); erythromycin (EES, E-Mycin, Erythrocin); fluoxetine (Prozac, Sarafem); ... consumerreports.org

HIV resistance mutations common but CXCR4 rare among untreated US …  -  May 22, 2007
Resistance to nevirapine (Viramune), delavirdine (Rescriptor), stavudine (Zerit), efavirenz (Sustiva), zidovudine (Retrovir), and nelfinavir (Viracept) were ... Aidsmap

Amprenavir (Systemic).(Drug overview)  -  Aug 1, 2006
Delavirdine (eg, Rescriptor) -- Use with amprenavir may lead to a possible resistance to delavirdine. They should not be administered together. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Emiliem Expands Management Team With Industry Veterans Donna …  -  May 7, 2008
While a scientist at The Upjohn Company, she invented Rescriptor(R), a non-nucleoside reverse transcriptase inhibitor currently marketed for the treatment ... Genetic Engineering News - Genetic Engineering News (press release)

Hydroxyurea (Systemic).  -  Oct 27, 2005
Agenerase) or Delavirdine (eg, Rescriptor) or Didanosine (eg, ddI, Videx) or Efavirenz (eg, Sustiva) or Indinavir (eg, Crixivan) or Lamivudine (eg, 3TC, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

CytoDyn Begins GMP Manufacturing of Its First-In-Class AIDS Drug  -  Jul 2, 2008
Several have been recently approved, including Sustiva(C) (efavirenz) from Bristol-Meyers Squibb (NYSE: BMY), and Rescriptor(C) (delavirdine) from Pfizer ... RedOrbit

Saquinavir (Systemic).(Drug overview)  -  May 1, 2006
Dilantin) or Rifabutin (eg, Mycobutin) -- These medicines may decrease the amount of saquinavir in the body Delavirdine (eg, Rescriptor) or Nevirapine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

48-Week Selzentry Data Show Promise for Drug-Resistant HIV  -  Sep 21, 2007
Because of potential drug interactions, OBR containing Rescriptor (delavirdine) or a protease inhibitor—other than Aptivus (tipranavir) —Selzentry dosing ... AIDSmeds.com HIV/AIDS Treatment News

Generic name product may also be available in the US  -  Jul 28, 2005
...or Chloramphenicol or Corticosteroids (cortisone-like medicine) or Delavirdine (eg, Rescriptor) or Digitalis glycosides (heart medicine) or Disopyramide ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

How to take Triazolam from Consumer Reports Health.  -  Jan 10, 2008
...delavirdine (Rescriptor), efavirenz (Sustiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); ... consumerreports.org

Rifapentine (Systemic).  -  Feb 1, 2006
Biaxin) or Corticosteroids (cortisone-like medicine) or Delavirdine (eg, Rescriptor) or Digitalis glycosides (heart medicine) or Diltiazem (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

UK approves Ab trial for HIV/AIDS  -  May 24, 2005
Pfizer's Delavirdine (Rescriptor), Boehringer Ingelheim Nevirapine (Viramune) are examples of drugs in this class. Protease Inhibitors (PIs) inhibit the ... DrugResearcher.com

St. John's Wort.(Drug overview)  -  Feb 1, 2007
...examples: indinavir (Crixivan(R)), delavirdine (Rescriptor(R)), lamivudine (Epivir(R)), nelfinavir (Viracept(R)), nevirapine (Viramune(R)), ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Rifapentine (Systemic).(Drug overview)  -  May 1, 2006
Biaxin) or Corticosteroids (cortisone-like medicine) or Delavirdine (eg, Rescriptor) or Digitalis glycosides (heart medicine) or Diltiazem (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Sun Herald : Be cautious with St. John's wort, other drugs  -  Jan 18, 2007
NNRTIs such as nevirapine (Viramune), delavirdine (Rescriptor), efavirenz (Sustiva); anti-migraine drugs such as sumatriptan (Imitrex); barbiturates; ... $2.95 - Sun Herald - NewsBank

Donna Romero: Coaching Pfizer to next drug discovery  -  Jul 24, 2006
Early in her career, Donna Romero, 45, focused on discovering anti-HIV drugs and helped discover one, Rescriptor. Now as one of the senior directors of ... St. Louis Business Journal

Press Release: Genetic Mutation Appears to Cause Asthma. - M2 …  -  Apr 10, 2008
Viramune) and delavirdine (Rescriptor) and because S-1153 is fully active in vitro against HIV containing the most common genetic mutation associated with ... Pay-Per-View - M2 Presswire - HighBeam Research

Article: Generic AIDS drugs.(CLINICAL CAPSULES)(approval for AIDS …  -  Aug 15, 2005
...response ... freeze the price of its two AIDS drugs, Viracept and Rescriptor ... or no health insurance for AIDS drugs are facing budgetary shortfalls . ... Pay-Per-View - Internal Medicine News - HighBeam Research

Fosamprenavir (Systemic).  -  Feb 1, 2006
Delavirdine (eg, Rescriptor) -- Use with fosamprenavir may lead to a possible resistance to delavirdine. They should not be administered together. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Fuzeon update.(Treatment News) | Article from HIV Treatment: ALERTS!...  -  Apr 1, 2005
700+ words ... ... approved medications for treating HIV/AIDS Protease Entry Nukes Non-nukes Inhibitors Inhibitors Combivir Rescriptor Agenerase Fuzeon ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Sustiva drug interactions.(FDA BITS) | Article from HIV Treatment: …  -  Jun 1, 2007
...at least 2 protease inhibitors or 1 protease inhibitor and a non-nucleoside reverse transcriptase inhibitor (i.e. Sustiva, Rescriptor, or Viramune). ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Multi-component drug delivery system: An emerging trend  -  Feb 15, 2006
Non-nucleoside Reverse Transcriptase Inhibitors (NnRTIs), which include delavirdine (Rescriptor), efavirenz (Sustiva), and nevirapine (Viramune). ... expresspharmapulse.com

New studies highlight HIV-resistance trends: NNRTIs show upward...  -  Jan 1, 2005
When investigators further divided the NNRTIs by drugs, they found that most of the drug resistance (16%) was to delavirdine (Rescriptor), she explains. ... Pay-Per-View - AIDS Alert - Factiva, from Dow Jones

Hydroxyurea (Systemic).(Drug overview)  -  May 1, 2006
Abacavir (eg, ABC, Ziagen) or Abacavir/Lamivudine/Zidovudine (eg, Trizivir) or Amprenavir (eg, Agenerase) or Delavirdine (eg, Rescriptor) or Didanosine (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Selzentry o Celsentri (maraviroc)  -  Mar 1, 2008
...de Aptivus [tripanavir] más Norvir [ritonavir]), o con Rescriptor (delavirdine) la dosis correcta es de una tableta de 150 mg dos veces al día. ... AIDSmeds.com HIV/AIDS Treatment News

Hepatitis warnings with Epivir.(be careful about abruptly stopping...  -  Apr 1, 2005
Inhibitors Inhibitors Combivir Rescriptor Agenerase Fuzeon (Epivir + Retrovir) Emtriva Sustiva Crixivan Epivir Viramune Fortovase Hivid Invirase Retrovir ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

St. John's Wort.(Health Aspects)  -  May 1, 2006
...examples: indinavir (Crixivan(R)), delavirdine (Rescriptor(R)), lamivudine (Epivir(R)), nelfinavir (Viracept(R)), nevirapine (Viramune(R)), ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Ã?ndice de lecciones  -  Mar 10, 2008
Sustiva (efavirenz), Viramune (nevirapine) y Rescriptor (delavirdine) pueden aumentar el nivel de Viracept en la sangre, aunque probablemente no sea ... AIDSmeds.com HIV/AIDS Treatment News

Ã?ndice de lecciones  -  May 11, 2007
Un tercer INNTR, Rescriptor (delavirdine), puede aumentar los niveles de Agenerase en la sangre. (Si se utilizan juntos, Agenerase puede disminuir ... AIDSmeds.com HIV/AIDS Treatment News

Article: One regimen, one pill, once a day.(New treatment combination)...  -  Apr 1, 2005
...and * Have failed at least 2 protease inhibitors or 1 protease inhibitor and a non-nucleoside reverse transcriptase inhibitor (i.e. Sustiva, Rescriptor, ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Espoirs en résistance majeure  -  Jul 31, 2008
Analogues non nucléosidiques inhibiteurs de la transcriptase inverse : Rescriptor® (delavirdine), Sustiva® (efavirenz), Viramune® (nevirapine). ... Act Up-Paris

Reyataz heart risks.(FDA Bits)(Food and drug administration)(Brief...  -  Apr 1, 2005
Rescriptor Agenerase Fuzeon (Epivir + Retrovir) Emtriva Sustiva Crixivan Epivir Viramune Fortovase Hivid Invirase Retrovir Kaletra Trizivir (Epivir + Lexiva ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Ã?ndice de lecciones  -  Jun 11, 2008
También es probable que Rescriptor (delavirdine), un tercer INNTR, aumente el nivel de Reyataz en la sangre. También es importante ser cuidadoso cuando se ... AIDSmeds.com HIV/AIDS Treatment News

Intelence (etravirine, TMC-125)  -  Jan 18, 2008
...otros antirretrovirales, incluyendo muchas cepas que son resistentes a los INNTR Sustiva (efavirenz), Viramune (nevirapine) y Rescriptor (delavirdine). ... AIDSmeds.com HIV/AIDS Treatment News

Kommissionsmodell „Off-Label-Use“ für den HIV-Bereich gefordert  -  Feb 10, 2005
...die Bundesknappschaft Recklinghausen die Erstattung des – in den USA zugelassenen - Virustatikums Rescriptor® mit dem Wirkstoff Delavirdin abgelehnt. ... journalmed.de

La thérapie contre le VIH  -  May 16, 2005
Delavirdine (Rescriptor ® ) est aussi accessible par autorisation temporaire d'utilisation (ATU). La troisième classe actuellement accessible de médicaments ... Aidsmap

Article: Non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV …  -  Jan 1, 2007
Article: Agouron Acquires Rescriptor From Pharmacia & Upjohn; ... PR Newswire; October 25, 1999 ; 700+ words ... ... tablets), a non-nucleoside reverse ... Pay-Per-View - Women's Health Activist - HighBeam Research

Article: Steered to right answer.(News) - Coventry Evening Telegraph...  -  Feb 25, 2006
Article: RESCRIPTOR(R)-Containing Combination Therapy May Be Effective For ... PR Newswire; September 8, 2000 ; 700+ words ... ... against HIV continues, ... Pay-Per-View - Coventry Evening Telegraph - HighBeam Research

Brand Names/Synonyms:
Rescriptor is also known by the following brand names and/or synonymsBHAP-U 90152; Bhap Der; DLV; Delavirdine; Rescriptor; SPP

Drug Category:
Rescriptor is categorized under the following by the FDA: Anti-HIV Agents; Nonnucleoside Reverse Transcriptase Inhibitors; ATC:J05AG02

Dosage Forms:
caplets

Absorption:
rapidly absorbed

Interactions:
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Chemical IUPAC Name:
N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl]methanesulfonamide





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