Rheumatrex

This page contains recent news articles, when available, and an overview of Rheumatrex but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Rheumatrex
(when available)

Pharmacology and use:
Methotrexate is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Methotrexate inhibits folic acid reductase which is responsible for the conversion of folic acid to tetrahydrofolic acid. At two stages in the biosynthesis of purines and at one stage in the synthesis of pyrimidines, one-carbon transfer reactions occur which require specific coenzymes synthesized in the cell from tetrahydrofolic acid. Tetrahydrofolic acid itself is synthesized in the cell from folic acid with the help of an enzyme, folic acid reductase. Methotrexate looks a lot like folic acid to the enzyme, so it binds to it quite strongly and inhibits the enzyme. Thus, DNA synthesis cannot proceed because the coenzymes needed for one-carbon transfer reactions are not produced from tetrahydrofolic acid because there is no tetrahydrofolic acid. Methotrexate selectively affects the most rapidly dividing cells (neoplastic and psoriatic cells). Methotrexate is also indicated in the management of severe, active, classical, or definite rheumatoid arthritis. For the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole; Severe psoriasis; Severe, active, classical or definite rheumatoid arthritis;

Mechanism Of Action:
Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading to inhibition of DNA synthesis and inhibition of cellular replication. The mechanism involved in its activity against rheumatoid arthritis is not known.

News Articles on Methotrexate

Medications for RA Linked to Skin Cancer  -  ‎Oct 20, 2009‎
Compared with people treated with other DMARDs such as Rheumatrex or Arava, people taking TNF blockers were 34% more likely to develop nonmelanoma skin ... WebMD

Arthritis; Pharma company extends voucher program for Rheumatrex …  -  Jan 1, 2005
Rheumatrex Dose Pack (methotrexate sodium tablets) is a once-weekly ... As a low-dosage oral methotrexate, Rheumatrex is an aggressive treatment for ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Abitrexate, Folex PFS, Mexate-AQ, MTX, Rheumatrex, Trexall  -  Aug 31, 2007
Methotrexate is similar to the vitamin called folic acid. It works by competing with folic acid in cells. This blocks the way the cell is able to make ... WebMD

Cumulative Deaths in Rheumatrex-treated Patients Reach 134: Wyeth  -  Feb 28, 2005
In the second week in February, the media reported that 134 deaths for which a causal relation with the adverse reaction could not be ruled out had occurred ... Pay-Per-View - Pharma Japan - Factiva, from Dow Jones

Patience needed for vitiligo treatment .  -  Sep 27, 2006
CT ANSWER: Methotrexate, one of whose brand names is Rheumatrex, is a drug used for many illnesses. In addition to rheumatoid arthritis, it has found a ... Sun Journal - Google News Archive

Article: Stada Pharmaceuticals.(Update) - Medical Marketing & Media |...  -  Jan 1, 2005
Article: Pharma company extends voucher program for Rheumatrex ... ... Stada relaunched in 2004) is Rheumatrex Dose Pack (methotrexate sodium ... ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Strong Arthritis Drugs Prove Safe and Effective in Children  -  Apr 20, 2005
Consider the use of Rheumatrex or Arava as described in this report in children ... More children in the Rheumatrex group improved as measured by the ACR ... MedPage Today

Cyclosporine Side Effects from Consumer Reports Health.  -  Jan 8, 2008
...cancer chemotherapy, methotrexate (Rheumatrex), sirolimus (Rapamune), ... methotrexate (Rheumatrex) or other medications that suppress the immune system ... consumerreports.org

Get Moving to Slow Down Rheumatoid Arthritis  -  Jan 13, 2005
Commonly prescribed DMARDS are methotrexate (Rheumatrexâ„¢) and sulfasalazine (Azalineâ„¢). While these drugs can have beneficial effects on the symptoms and ... npicenter.com

Stada Pharmaceuticals Inc.(RX/GENERIC DRUGS--Profiles)(Company …  -  Sep 26, 2005
Stada repackaged Rheumatrex in compliance-friendly packaging, developed a comprehensive patient compliance and education program, and launched it with a ... Free with registration - Chain Drug Review - AccessMyLibrary.com

Aggressive Therapy for Crohn's Disease Produces Better Outcomes  -  Feb 22, 2008
Then, if side effects or steroid resistance develop, it moves on to broad-spectrum immunosuppressive drugs such as Rheumatrex (methotrexate). ... Washington Post

Juvenile rheumatoid arthritis  -  Oct 19, 2007
Commonly used DMARDs for children include methotrexate (Rheumatrex) and sulfasalazine (Azulfidine). Side effects of methotrexate may include nausea, ... CNN International

Churg-Strauss syndrome  -  Nov 14, 2006
However, other people require another immunosuppressive drug, such as cyclophosphamide (Cytoxan) azathioprine (Imuran) or methotrexate (Rheumatrex), ... cnn.com

Adult Still's disease  -  Sep 13, 2008
The medication methotrexate (Rheumatrex) has been used successfully in a small series of people to treat adult Still's disease. ... CNN

Wegener's granulomatosis  -  Sep 25, 2006
However, most people require another immunosuppressive drug, such as cyclophosphamide (Cytoxan), azathioprine (Imuran) or methotrexate (Rheumatrex), ... cnn.com

Stada Pharmaceuticals Inc.(RX/GENERIC DRUGS--Profiles)(Company …  -  Sep 26, 2005
Stada repackaged Rheumatrex in compliance-friendly packaging, developed a comprehensive patient compliance and education program, and launched it with a ... Pay-Per-View - Chain Drug Review - HighBeam Research

ASK AN EXPERT  -  May 15, 2008
These medications, such as azathioprine (Imuran) or methotrexate (Rheumatrex), help keep your immune system from attacking healthy tissue. ... CNN

Takayasu's arteritis  -  Nov 2, 2006
...off the medication, you may need treatment with cytotoxic drugs, such as methotrexate (Rheumatrex), azathioprine (Imuran) or cyclophosphamide (Cytoxan). ... cnn.com

Collagenous colitis/lymphocytic colitis  -  Oct 3, 2006
Other drugs, such as the immunosuppressive agents methotrexate (Rheumatrex) and azathioprine (Imuran), are more powerful medications that may be associated ... cnn.com

Ulcerative Colitis Medications - Ulcerative Colitis Health Information...  -  Feb 20, 2008
Methotrexate (MTX, Rheumatrex) is another fast-acting type of injectable immunosuppressant that is effective for Crohn's disease. ... New York Times

Rheumatoid arthritis  -  Sep 18, 2008
...the gold compound auranofin (Ridaura), sulfasalazine (Azulfidine), minocycline (Dynacin, Minocin) and methotrexate (Rheumatrex). Immunosuppressants. ... CNN International

Takayasu's arteritis  -  Nov 1, 2008
...such as methotrexate (Rheumatrex) or azathioprine (Imuran). These drugs suppress the inflammation in your blood vessels, but they have risks. ... CNN

Safe Practice Guidelines for Oral Chemotherapy Found Gravely Lacking  -  Jan 12, 2007
The drugs included Xeloda (capecitabine), Cytoxan (cyclophosphamide), Iressa (gefitinib), Gleevec (imatinib), oral Rheumatrex (oral methotrexate), ... MedPage Today

Article: Local Focus.(Business) - Daily Herald (Arlington Heights,...  -  Jul 6, 2005
Article: Lederle launches Rheumatrex methotrexate dose pack to treat ... PR Newswire; January 9, 1989 ; 700+ words ... ... LAUNCHES RHEUMATREX(R) ... Pay-Per-View - Daily Herald - HighBeam Research

Aggressive therapy for Crohn's disease produces better outcomes  -  Feb 25, 2008
Then, if side effects or steroid resistance develop, it moves on to broad-spectrum immunosuppressive drugs such as Rheumatrex (methotrexate). ... Tehran Times

EULAR: Rheumatoid Arthritis Response Quicker to Certolizumab  -  Jun 15, 2007
In the study, patients whose disease was not responding to methotrexate (Rheumatrex, Trexall) were randomized to placebo or 200 mg or 400 mg of ... MedPage Today

The promise of stem cells: using stem cells to conquer disease is an ...  -  Apr 1, 2005
Methotrexate (Rheumatrex, Folex PFS). 18. Researchers are directing efforts to treat all the following with stem cell transplantation EXCEPT: a. Diabetes. ... Pay-Per-View - RN - Factiva, from Dow Jones

Rituxan and Other Emerging Agents Will Find Success When Used in …  -  Aug 29, 2007
...generics; Merck's Decadron, generics; Stada Pharmaceuticals' Rheumatrex, generics; Pfizer's Cytosar-U/Aracytine, Nippon Shinyaku's Cylocide, generics; ... Free with registration - PR Newswire - AccessMyLibrary.com

Research Suggests Arthritis Drug Needs Second Chance  -  Apr 24, 2006
Typical rheumatoid arthritis symptoms can be treated with methotrexate, known by its brand name, Rheumatrex. It's a commonly used drug that has long treated ... WJACtv.com

Abortion Pills Don't Cause Future Problems  -  Aug 20, 2007
There are three available regimens at this time; misoprostol (Cytotec) alone, methotrexate (Rheumatrex) followed by misoprostol, and mifepristone (Mifeprex, ... Ivanhoe Broadcast News

Can-Fite Submits Study Details for FDA Approval  -  Jan 24, 2006
...include Stada Pharmaceuticals' Rheumatrex and Barr's Trexall), in preparation to the phase IIb study that is scheduled to begin within a few months. ... RedOrbit

Infliximab Injection Side Effects from Consumer Reports Health.  -  Jan 4, 2007
Sandimmune), oral corticosteroids; 6-mercaptopurine (Purinethol); methotrexate (Rheumatrex), sirolimus (Rapamune), and tacrolimus (Prograf). ... consumerreports.org

Crohn's disease  -  Aug 10, 2005
Methotrexate (Rheumatrex). This drug, normally used to treat cancer, is sometimes used for people with Crohn's disease who don't respond well to other ... cnn.com

How to take Fenoprofen from Consumer Reports Health.  -  Jan 1, 2006
...diuretics ('water pills'); lithium (Eskalith, Lithobid); oral medications for diabetes ; methotrexate (Rheumatrex); phenobarbital; phenytoin (Dilantin); ... consumerreports.org

Copyright Harvard Health Publications 2007  -  Aug 27, 2007
...methotrexate (Folex, Methotrexate LPF, Rheumatrex), cyclophosphamide (Cytoxan, Neosar), mitoxantrone (Novantrone) and cladribine (Leustatin). HealthCentral.com

ACR: Novel Oral Agent Improves Rheumatoid Arthritis Symptoms  -  Oct 28, 2008
All participants were taking stable doses of methotrexate (Rheumatrex, Trexall) but were on no other DMARDs, including biologics. ... MedPage Today

How to take Co-trimoxazole Injection from Consumer Reports Health.  -  Jan 8, 2006
...diabetes medications, diuretics ('water pills'), medications for seizures such as phenytoin (Dilantin), methotrexate (Folex, Rheumatrex), and vitamins. ... consumerreports.org

Rheumatoid Arthritis - Treatment  -  Jan 16, 2007
Methotrexate (Rheumatrex, Trexall) is the most widely used of these drugs. Biologic Response Modifiers (also known as Biologic DMARDs) are often prescribed ... HealthCentral.com

The reason for those liver tests.  -  Mar 25, 2005
...methotrexate (Rheumatrex), methsuximide (Celontin), methyldopa (Aldomet), nabumetone (Relafen), nefazodone (Serzone), naproxen (Naprosyn, Aleve), ... Free with registration - Sun Herald - AccessMyLibrary.com

Treatments and drugs  -  Nov 14, 2008
Other people may require another immunosuppressive drug, such as cyclophosphamide (Cytoxan), azathioprine (Imuran) or methotrexate (Rheumatrex, Trexall), ... MayoClinic.com

Epirubicin (Systemic ).(Drug overview)  -  May 1, 2006
Purinethol) or Methotrexate (eg, Rheumatrex) or Plicamycin (eg, Mithracin) -- Concurrent use with epirubicin increases the risk of infection and may ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Telbivudine Side Effects from Consumer Reports Health.  -  Jan 5, 2007
...medications to treat human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS);methotrexate (Rheumatrex);niacin (nicotinic acid) ... consumerreports.org

Harvard Pilgrim Health Care:  -  May 19, 2007
These drugs include methotrexate (Folex, Methotrexate LPF, Rheumatrex), hydroxychloroquine (Plaquenil) or sulfasalazine (Azulfidine). Each o. Intelihealth.com

How to take Interferon beta-1a Intramuscular Injection from Consumer ...  -  Jan 4, 2006
...isoniazid (INH, Nydrazid);medications for acquired immunodeficiency syndrome (AIDS) or human immunodeficiency virus (HIV);methotrexate (Rheumatrex); ... consumerreports.org

Natalizumab Injection Side Effects from Consumer Reports Health.  -  Jan 3, 2008
...methotrexate (Rheumatrex); mitoxantrone (Novantrone); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), prednisolone, ... consumerreports.org

Treatment for rare liver disease increases mortality risk  -  Aug 24, 2005
The brand names for methotrexate are Rheumatrex and Trexall. "We do not advocate the use of methotrexate for patients with primary biliary cirrhosis," ... Medical News Today - Medical News Today (press release)

How to take Amiodarone from Consumer Reports Health.  -  Jan 11, 2008
Claritin); medications for diabetes or seizures; methotrexate (Rheumatrex); narcotic medications for pain; and rifampin (Rifadin, Rimactane). ... consumerreports.org

Copyright Harvard Health Publications 2007  -  Aug 27, 2007
Rheumatrex) may be recommended. However, these medications may cause side effects, and you have to be monitored regularly while you are taking them. ... HealthCentral.com

How to take Alefacept Injection from Consumer Reports Health.  -  Jan 4, 2006
...cyclosporine (Neoral, Sandimmune); methotrexate (Rheumatrex); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), ... consumerreports.org

Methotrexate and Polymyalgia Rheumatica Therapy  -  Sep 1, 2005
Methotrexate (Rheumatrex) has been used to reduce inflammation in rheumatoid arthritis, systemic vasculitis, and giant cell arteritis, and in small studies ... AAFP News Now

Learn about Leucovorin from Consumer Reports Health.  -  Jan 7, 2008
Leucovorin is used to prevent harmful effects of methotrexate (Rheumatrex, Trexall; cancer chemotherapy medication) when methotrexate is used to to treat ... consumerreports.org

Japan to discuss pediatric drug use.(Attention deficit hyperactivity ...  -  Apr 3, 2006
Wyeth's Rheumatrex (methotrexate) for the treatment of juvenile idiopathic arthritis; GlaxoSmithKline's Botox (botulinum toxin type A) for the treatment ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Crohn's Disease  -  Aug 27, 2007
...budesonide (Entocort), azathioprine (Imuran), 6-mercaptopurine (Purinethol), cyclosporine (Neoral, Sandimmune) and methotrexate (Rheumatrex, Folex). HealthCentral.com

Comfrey.  -  May 1, 2006
Methotrexate (Folex(R), Rheumatrex(R))) * Medicine used to treat infection (Itraconazole (Sporanox(R)); Ketoconazole (Nizoral(R)); Terbinafine (Lamisil(R))) ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Soriatane.(Drug overview)  -  Jan 22, 2007
Soriatane must never be taken with the drugs methotrexate (Rheumatrex and Trexall) or tetracycline antibiotics (such as Achromycin V and Sumycin). ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Dr. Isadore Rosenfeld's 2005 Breakthrough Health  -  Jan 13, 2005
For the past 20 years, the DMARD of choice has been methotrexate (Rheumatrex), originally developed for the treatment of various cancers. ... Buzzle

How to take Diclofenac from Consumer Reports Health.  -  Jan 1, 2008
...digoxin (Lanoxin); diuretics ('water pills'); insulin and oral medication for diabetes;lithium (Eskalith, Lithobid); and methotrexate (Rheumatrex). ... consumerreports.org

How to take Ibuprofen from Consumer Reports Health.  -  Jan 12, 2008
Lithobid); and methotrexate (Rheumatrex). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects. ... consumerreports.org

Ketoconazole Side Effects from Consumer Reports Health.  -  Jan 4, 2005
...pravastatin (Pravachol), or simvastatin (Zocor); isoniazid (INH, Nydrazid); methotrexate (Rheumatrex); niacin (nicotinic acid); or rifampin. ... consumerreports.org

3. Coping with arthritis.(Disease/Disorder overview)  -  Jan 22, 2007
Azathioprine (Imuran) and cyclosporine (Neoral) are approved for use in RA cases. Methotrexate (Rheumatrex) is now frequently prescribed as wel. Free with registration - PDR Family Guide to Prescription Drugs... - AccessMyLibrary.com

Erythromycin and Sulfisoxazole (Systemic).(Drug overview)  -  May 1, 2006
Plaquenil) or Mercaptopurine (eg, Purinethol) or Methotrexate (eg, Mexate, Rheumatrex) or Methyldopa (eg, Aldomet) or Naltrexone (eg, Trexan) (with ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Enbrel.(Drug overview)  -  Jan 22, 2007
It can be added to methotrexate (Rheumatrex) therapy when methotrexate fails to provide adequate relief. Prescribed alone, it is also used for juvenile ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Treatment for rare liver disease increases mortality risk  -  Aug 29, 2005
The brand names for methotrexate are Rheumatrex and Trexall. "We do not advocate the use of methotrexate for patients with primary biliary cirrhosis," ... i-newswire.com

Kava.  -  May 1, 2006
Medicines used to treat cancer or rheumatoid arthritis (examples: Carmustine (BiCNU(R)); Methotrexate (Folex(R), Rheumatrex(R)); ... Free with registration - AltCareDex Alternative Medicines - AccessMyLibrary.com

Epirubicin (Systemic ).  -  Feb 1, 2006
Purinethol) or Methotrexate (eg, Rheumatrex) or Plicamycin (eg, Mithracin) -- Concurrent use with epirubicin increases the risk of infection and may ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Busulfan (Systemic).  -  Aug 1, 2006
Ludiomil) or Mercaptopurine (eg, Purinethol) or Methotrexate (eg, Rheumatrex) or Penicillamine (eg, Cuprimine) or Pimozide (eg, Orap) or Plicamycin (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Efalizumab Injection Side Effects from Consumer Reports Health.  -  Jan 12, 2008
...cyclosporine (Neoral, Sandimmune); methotrexate (Rheumatrex); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), ... consumerreports.org

Treatment for Rare Liver Disease Increases Mortality Risk  -  Sep 28, 2005
The brand names for methotrexate are Rheumatrex and Trexall. "We do not advocate the use of methotrexate for patients with primary biliary cirrhosis," ... emaxhealth.com

Hydroxyurea (Systemic).(Drug overview)  -  May 1, 2006
Ancobon) or Ganciclovir (eg, Cytovene) or Mercaptopurine (eg, Purinethol) or Methotrexate (eg, Rheumatrex) or Plicamycin (eg, Mithracin) or Zidovudine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Busulfan (Systemic).  -  Jul 28, 2005
Ludiomil) or Mercaptopurine (eg, Purinethol) or Methotrexate (eg, Rheumatrex) or Penicillamine (eg, Cuprimine) or Pimozide (eg, Orap) or Plicamycin (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

How to take Desoximetasone Topical from Consumer Reports Health.  -  Jan 7, 2005
Be sure to mention medications that suppress the immune system such as azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), methotrexate (Rheumatrex), ... consumerreports.org

Adefovir Side Effects from Consumer Reports Health.  -  Jan 7, 2005
...isoniazid (INH, Nydrazid); medications to treat HIV or AIDS; methotrexate (Rheumatrex); niacin (nicotinic acid); or rifampin (Rifadin, Rimactane). ... consumerreports.org

How to take Cyanocobalamin Nasal from Consumer Reports Health.  -  Jan 4, 2005
...as lamivudine (Epivir) and zidovudine (Retrovir); methotrexate (Rheumatrex, Trexall), para-aminosalicylic acid (Paser), and pyrimethamine (Daraprim). ... consumerreports.org

Hydroxyurea (Systemic).  -  Oct 27, 2005
Intron A, Roferon-A) or Mercaptopurine (eg, Purinethol) or Methotrexate (eg, Rheumatrex) or Plicamycin (eg, Mithracin) or Zidovudine (eg, AZT, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Erythromycin and Sulfisoxazole (Systemic).  -  Oct 27, 2005
Plaquenil) or Mercaptopurine (eg, Purinethol) or Methotrexate (eg, Mexate, Rheumatrex) or Methyldopa (eg, Aldomet) or Naltrexone (eg, Trexan) (with ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Etanercept Injection Side Effects from Consumer Reports Health.  -  Jan 6, 2008
6-mercaptopurine (Purinethol), methotrexate (Rheumatrex), sirolimus (Rapamune), sulfasalazine (Azulfidine), and tacrolimus (Prograf). ... consumerreports.org

How to take Minocycline Oral from Consumer Reports Health.  -  Jan 10, 2005
...methysergide (Sansert), and pergolide (Permax) iron products, isoniazid (INH, Nydrazid), methotrexate (Rheumatrex), niacin (nicotinic acid), penicillin, ... consumerreports.org

Stada Pharmaceuticals.(Update)  -  Jan 1, 2005
Stada Pharmaceuticals in Cranbury, N.J., has extended its Trial Script voucher program for Rheumatrex Dose Pack to August 2005. Free with registration - Medical Marketing & Media - AccessMyLibrary.com

Imatinib (Systemic).(Drug overview)  -  May 1, 2006
Intron A, Roferon-A) or Mercaptopurine (eg, Purinethol) or Methotrexate (eg, Rheumatrex) or Plicamycin (eg, Mithracin) or Zidovudine (eg, AZT, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Managing cutaneous vasculitis in a patient with lupus erythematosus.(...  -  Feb 1, 2007
Additionally, his routine medications include mycophenolate mofetil (CellCept[R]), methotrexate (Rheumatrex[R]), folic acid, clopidogreland (Plavix), ... Free with registration - Dermatology Nursing - AccessMyLibrary.com

Rheumatoid arthritis.(Adult Health Advisor 2007)(Disease/Disorder …  -  May 31, 2007
One example of a DMARD is methotrexate (Rheumatrex or Trexall). Treatment with DMARDs has to be watched carefully by your provider to avoid serious side ... $4.95 - Clinical Reference Systems - ECNext

Use of Biologics Pushed to Later Lines of Therapy Due to Uptake of...  -  Nov 15, 2007
Methotrexate (DAVA's Rheumatrex and generics) replaces Enbrel as the patient-share leader among second-line systemic therapies. ... $4.95 - PR Newswire - ECNext

Press of Atlantic City, The : QUESTION & ANSWER FROM THE …  -  Mar 28, 2005
...methotrexate (Rheumatrex), methsuximide (Celontin), methyldopa (Aldomet), nabumetone (Relafen), nefazodone (Serzone), naproxen (Naprosyn, Aleve), ... $2.95 - Press of Atlantic City, The - NewsBank

Press Release: Use of Biologics Pushed to Later Lines of Therapy Due...  -  Nov 15, 2007
Methotrexate (DAVA's Rheumatrex and generics) replaces Enbrel as the patient-share ... Read all of this article with a FREE trial ... Pay-Per-View - PR Newswire - HighBeam Research

Rheumatoid arthritis.(Disease/Disorder overview)  -  May 24, 2006
One example of a DMARD is methotrexate (Rheumatrex, Trexall). Treatment with DMARDs has to be watched carefully by your provider to avoid side effects. ... $4.95 - Clinical Reference Systems - ECNext

Southern Illinoisan : Lifestyles<br>  -  Mar 29, 2005
...methotrexate (Rheumatrex), methsuximide (Celontin), methyldopa (Aldomet), nabumetone (Relafen), nefazodone (Serzone), naproxen (Naprosyn, Aleve), ... $2.95 - Southern Illinoisan - NewsBank

Rheumatoid arthritis.(Adult Health Advisor 2006)(Disease/Disorder …  -  Nov 1, 2006
One example of a DMARD is methotrexate (Rheumatrex, Trexall). Treatment with DMARDs has to be watched carefully by your provider to avoid side effects. ... $4.95 - Clinical Reference Systems - ECNext

Federal Register 2006 - 71 FR 59801 Public Teleconference Regarding …  -  Oct 11, 2006
They are beneficial in over 70% of patients including many who have not responded to Rheumatrex ® (Methotrexate-an antimetabolite by STADA); however, ... Pay-Per-View - Federal Register 2006 - Loislaw

Press Release: Rituxan and Other Emerging Agents Will Find Success …  -  Aug 29, 2007
...generics; Merck's Decadron, generics; Stada Pharmaceuticals' Rheumatrex, generics; Pfizer's Cytosar-U/Aracytine, Nippon Shinyaku's Cylocide, generics; ... Pay-Per-View - PR Newswire - HighBeam Research

Southern Illinoisan : Lifestyles<br>  -  Sep 20, 2005
...methotrexate (Rheumatrex), methsuximide (Celontin), methyldopa (Aldomet), nabumetone (Relafen), nefazodone (Serzone), naproxen (Naprosyn, Aleve), ... $2.95 - Southern Illinoisan - NewsBank

Managing cutaneous vasculitis in a patient with lupus erythematosus.(...  -  Feb 1, 2007
Additionally, his routine medications include mycophenolate mofetil (CellCept[R]), methotrexate (Rheumatrex[R]), folic acid, clopidogreland (Plavix), ... $4.95 - Dermatology Nursing - ECNext

khoa hoc@doi song/Phai chang thien nhien la vo hai  -  Mar 22, 2007
Kỵ các loại thuốc corticostéroides (Prednisone, Decadron), các steroides anabolisants (Winstrol), Amiodarone (Cordarone), Methotrexate (Rheumatrex) và ... Khoa H�c

khoa hoc@doi song/Phai chang thien nhien la vo hai ?  -  Dec 8, 2005
Kỵ các loại thuốc corticostéroides ( Prednisone, Decadron ), các steroides anabolisants ( Winstrol), Amiodarone ( Cordarone), Methrotrexate (Rheumatrex) ,và ... Khoa H�c

Traveler's diarrhea.  -  Jun 1, 2005
...(Rheumatrex) Avoid in patients taking doxycycline (Vibramycin) for malaria prophylaxis. Lactobacillus GG Optimal dosing not Safe; more studies ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Traveler's diarrhea.  -  Jun 1, 2005
...three weeks probenecid (Benemid), or methotrexate (Rheumatrex) Avoid in patients taking doxycycline (Vibramycin) for malaria prophylaxis. ... $4.95 - American Family Physician - ECNext

Evaluation of chronic dyspnea.  -  Apr 15, 2005
Methotrexate (Rheumatrex): lung fibrosis Illicit drugs (e.g., heroin): talcosis History of immunosuppressive Opportunistic infections: ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Evaluation of chronic dyspnea.  -  Apr 15, 2005
...airway disease Amiodarone (Cordarone)/nitrofu- rantoin (Furadantin): pneumonitis Methotrexate (Rheumatrex): lung fibrosis Illicit drugs (e.g., ... $4.95 - American Family Physician - ECNext

Press Release: 4SC AG: Patient Treatment in Phase IIa Clinical Trial ...  -  Oct 8, 2007
Article: STADA Pharmaceuticals Relaunches Rheumatrex(R) (Methotrexate ... PR Newswire; July 9, 2004 ; 700+ words ... ... Arzneimittel AG (OTC Pink Sheets ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: 4SC AG: Patient Recruitment Successfully Completed for...  -  Jun 28, 2007
Article: STADA Pharmaceuticals Relaunches Rheumatrex(R) (Methotrexate ... PR Newswire; July 9, 2004 ; 700+ words ... ... Arzneimittel AG (OTC Pink Sheets ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Synta Pharmaceuticals to Focus 2006 Development on Its...  -  Dec 23, 2005
Article: STADA Pharmaceuticals Relaunches Rheumatrex(R) (Methotrexate ... PR Newswire; July 9, 2004 ; 700+ words ... ... moderate and severe rheumatoid ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: 4SC Nominates NFkB Development Candidate and …  -  Jan 23, 2007
Article: STADA Pharmaceuticals Relaunches Rheumatrex(R) (Methotrexate ... PR Newswire; July 9, 2004 ; 700+ words ... ... Arzneimittel AG (OTC Pink Sheets ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Brand Names/Synonyms:
Rheumatrex is also known by the following brand names and/or synonymsAbitrexate; Amethopterin; Amethopterine; Antifolan; Arbitrexate; Emtexate; Folex; Folex Pfs; HDMTX; L-Amethopterin; Ledertrexate; MTX; Metatrexan; Methopterin; Methotextrate; Methotrate; Methotrexat; Methotrexate; Methotrexate Lpf; Methotrexate Preservative Free; Methotrexate Sodium; Methotrexate for Injection; Methotrexate, Usp Grade; Methylaminopterin; Methylaminopterinum; Mexate; Mexate-Aq; Mexate-Aq Preserved; N-Bismethylpteroylglutamic Acid; NSC 740; R 9985; Rheumatrex; Rheumatrex Dose Pack; Trexall; X 133

Drug Category:
Rheumatrex is categorized under the following by the FDA: Antirheumatic Agents; Immunosuppressive Agents; Dermatologic Agents; Antimetabolites; Abortifacient Agents; Antineoplastic Agents; ATC:L01BA01; ATC:L04AX03

Dosage Forms:
Tablets

Absorption:
Well absorbed <30 mg/m², 20%

Interactions:
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Chemical IUPAC Name:
2-[4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]aminopentanedioicacid





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