Rifabutin

This page contains recent news articles, when available, and an overview of Rifabutin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Rifabutin
(when available)

Pharmacology and use:
Rifabutin is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. It is bactericidal and has a very broad spectrum of activity against most gram-positive and gram-negative organisms (including Pseudomonas aeruginosa) and specifically Mycobacterium tuberculosis. Because of rapid emergence of resistant bacteria, use is restricted to treatment of mycobacterial infections and a few other indications. Rifabutin is well absorbed when taken orally and is distributed widely in body tissues and fluids, including the CSF. It is metabolized in the liver and eliminated in bile and, to a much lesser extent, in urine, but dose adjustments are unnecessary with renal insufficiency. Used to prevent mycobacterial infection in immunocompromised patients, as a therapy in non-tuberculous mycobacterial infection, and as a treatment in pulmonary tuberculous.

Mechanism Of Action:
Rifabutin acts via the inhibition of DNA-dependent RNA polymerase, leading to a suppression of RNA synthesis and cell death.

News Articles on Rifabutin

Researchers target first new TB vax in decades  -  ‎Dec 10, 2009‎
The Bacille Calmette-Guerin shot was developed in 1920, and with the exception of rifabutin, there has been no new drug for TB in more than 40 years. ... FierceVaccines

Novartis drug Tasigna(R) meets primary endpoint in pivotal trial against ...  -  ‎Oct 19, 2009‎
...dexamethasone, phenytoin, carbamazepine, rifampin, rifabutin, rifapentin, phenobarbital). Patients should also refrain from taking St John's Wort. ... Reuters

… endothelial deposits associated with rifabutin treatment in Crohn's...  -  Mar 11, 2005
Correspondence: A Mitra, Department of Ophthalmology, Epsom and St Helier University Hospitals NHS Trust, Sutton Hospital, Cotswold Road, Sutton SM2 5NF, ... Nature.com

Rifabutin (Systemic).(Drug overview)  -  May 1, 2006
Rifabutin (rif-a-BUE-tin) is used to help prevent Mycobacterium avium complex (MAC) disease from causing disease throughout the body in patients with ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… with concurrent administration of rifabutin and lopinavir/ritonavir...  -  Oct 26, 2007
A 41-year-old HIV-infected man received lamivudine/zidovudine and nevirapine therapy. He also took isoniazid/rifampicin/pyrazinamide and ethambutol for ... Nature.com

Lower Doses of Mycobutin (Rifabutin), Every Other Day, May Offer as …  -  Dec 23, 2005
By Paula Moyer. WASHINGTON, DC -- December 23, 2005 -- Patients with advanced HIV who receive prophylactic rifabutin (Mycobutin) along with highly active ... DG News

… Interaction Between Anti-TB Agent Rifabutin and HIV Drug Rilpivirin...  -  Aug 8, 2008
By Kate Jongbloed. MEXICO CITY -- August 8, 2008 -- Clinical tests indicate an interaction between the antituberculosis drug rifabutin and the ... DG News

RIFABUTIN (Oral route) - rif-a-BYOO-tin.(Drug overview)  -  May 1, 2007
Rifabutin is used to help prevent Mycobacterium avium complex (MAC) disease from causing disease throughout the body in patients with advanced human ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Rifabutin (Systemic).  -  Oct 27, 2005
Rifabutin (rif-a-BUE-tin) is used to help prevent Mycobacterium avium complex (MAC) disease from causing disease throughout the body in patients with ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Acquired Rifamycin Resistance With Twice-Weekly Treatment of HIV- …  -  Feb 9, 2006
Rationale: Rifabutin was recommended in place of rifampin during treatment ... Objective: To evaluate the activity of intermittent rifabutin- based therapy. ... RedOrbit

Rifabutin-based regimens tackle resistant H. pylori.(News)(treatment-...  -  May 15, 2006
NICE, FRANCE -- Two different rifabutin-based, triple-therapy approaches proved to be safe and effective therapies in two European trials involving patients ... Free with registration - Family Practice News - AccessMyLibrary.com

Rifabutin-based regimens tackle resistant H. pylori.(News)(treatment-...  -  May 15, 2006
Rifabutin-based regimens tackle resistant H. pylori.(News)(treatment-resistant Helicobacter pylori)(Clinical report) ... find Family Practice News articles. Pay-Per-View - Family Practice News - HighBeam Research

Amprenavir (Systemic).(Drug overview)  -  Aug 1, 2006
Rifabutin (eg, Mycobutin) -- Use of amprenavir can cause increased blood levels of rifabutin. Rifabutin can cause decreased blood levels of amprenavir. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Ritonavir Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Sep 30, 2008
When taken with ritonavir, your body may not process rifabutin properly. When rifabutin is taken with ritonavir, your blood levels of rifabutin may increase ... WebMD

Guidelines Updated on Managing Drug Interactions With HIV-Related TB  -  Feb 6, 2008
Rifabutin has little effect on protease-inhibitor concentrations, but there are marked increases in rifabutin concentrations with this combination regimen. ... Medscape

Rifampicin resistance linked to dosing schedule in HIV-positive TB …  -  Jun 13, 2005
The study also showed that the risk of resistance was not affected by whether the patients took rifampicin or the similar drug rifabutin (Mycobutin). ... Aidsmap

H. pylori Treatment: New Wine in Old Bottles?  -  Jul 28, 2008
Levofloxacin and rifabutin are alternative treatments for patients in whom standard ... Rifabutin is a drug used to treat mycobacterial infections. ... Nature.com

Article: Don't let this happen to you.(FEEDBACK) - Macworld |...  -  May 1, 2005
Article: Rifabutin should be given to patients to prevent . ... After reviewing new data on rifabutin (Mycobutin), the U.S. Food and Drug Administration's ... Pay-Per-View - Macworld - HighBeam Research

Drug Resistance; Acquired rifamycin resistance risk increases with...  -  Mar 28, 2006
..."To evaluate the activity of intermittent rifabutin-based therapy, patients with culture-confirmed TB were treated under direct supervision with 2 mo of ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Updated Guidelines on Managing Drug Interactions in the Treatment of ...  -  Feb 1, 2008
Updated guidelines for the use of rifabutin or rifampin for the treatment and prevention of tuberculosis among HIV-infected patients taking protease ... Pay-Per-View - MMWR. Morbidity and Mortality Weekly... - HighBeam Research

Update on tuberculosis -- 2005  -  Mar 1, 2006
..."Thus, rifabutin-based therapy appears to be a better choice for HIV ... However, another research study showed that rifabutin therapy for advanced ... eurekalert.org

A Reduction In Tuberculosis Incidence, Prevalence And Death Rate Can ...  -  Mar 4, 2006
..."Thus, rifabutin-based therapy appears to be a better choice for HIV ... However, another research study showed that rifabutin therapy for advanced ... Medical News Today - Medical News Today (press release)

How is it treated or prevented?  -  Jun 6, 2006
If you are being treated for both M. kansasii and HIV, a better option is rifabutin. However, the dose of rifabutin may still need to be adjusted, ... AIDSmeds.com HIV/AIDS Treatment News

Researchers find how some antibiotics kill bacteria  -  Dec 8, 2005
The higher-resolution images also showed that rifapentin and rifabutin each bind just a little differently to E. coli, but still bring about the same ... innovations report - Innovations-Report

Recurrent Tuberculosis in the United States and Canada: Relapse or …  -  Jan 1, 2005
TBTC study 23 was a study of patients who were HIV infected with tuberculosis treated with isoniazid, rifabutin, ethambutol, and pyrazinamide for the first ... RedOrbit

Amprenavir (Systemic).  -  Jul 28, 2005
Rifabutin (eg, Mycobutin) -- Use of amprenavir can cause increased blood levels of rifabutin. Rifabutin can cause decreased blood levels of amprenavir. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Fosamprenavir (Systemic).  -  Feb 1, 2006
Rifabutin (eg, Mycobutin) -- Use of fosamprenavir can cause increased blood levels of ... Rifabutin can cause decreased blood levels of fosamprenavir. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Hypersensitivity pneumonitis-like granulomatous lung disease with …  -  Feb 1, 2007
The duration of antimycobacterial therapy included 6 months of rifabutin, azithromycin, and ethambutol for case 1, and 9 months of levafloxacin and ... Free with registration - Environmental Health Perspectives - AccessMyLibrary.com

Article: DOLPHIN BOOST.(News) - The Mirror (London, England) | …  -  Nov 25, 2005
Article: Rifabutin/Protease Inhibitors Successfully Treat TB ... ... Alternative combinations are needed for coinfected patients * Rifabutin combined with ... Pay-Per-View - The Mirror - HighBeam Research

Fosamprenavir (Systemic).(Drug overview)  -  May 1, 2006
Rifabutin (eg, Mycobutin) -- Use of fosamprenavir can cause increased blood levels of ... Rifabutin can cause decreased blood levels of fosamprenavir. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Drug Resistance; Researchers find how some antibiotics kill bacteria  -  Sep 2, 2005
The higher-resolution images also showed that rifapentin and rifabutin each bind just a little differently to E. coli, but still bring about the same ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Isolated skin ulcers due to Mycobacterium tuberculosis in a renal...  -  Apr 5, 2007
23 Rifabutin is a less potent inducer of cytochrome p450 3A4 microsomal ... (2004) Treatment of tuberculosis with rifabutin in a renal transplant recipient. ... Nature.com

Effectiveness Confirmed for Multi-Drug Treatment of XDR-TB  -  Aug 25, 2008
Isoniazid, amikacin, levofloxacin, moxifloxacin, and rifabutin were used only rarely, but 80% or more of XDR-TB patients received capreomycin, ofloxacin, ... MedPage Today

Ohio State University; Researchers find how some antibiotics kill...  -  Aug 31, 2005
The higher-resolution images also showed that rifapentin and rifabutin each bind just a little differently to E. coli, but still bring about the same ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Hypersensitivity pneumonitis-like granulomatous lung disease with …  -  Feb 1, 2007
The duration of antimycobacterial therapy included 6 months of rifabutin, azithromycin, and ethambutol for case 1, and 9 months of levafloxacin and ... $4.95 - Environmental Health Perspectives - ECNext

Literature Commentary by Dr. John Bartlett: Lymphadenitis RCT, Dec '...  -  Jan 2, 2008
Of these, 88% were sensitive to clarithromycin and 89% were sensitive to rifabutin. In regard to outcome, cure was achieved in 96% of those who underwent ... Medscape

Tuberculosis, a neglected opportunity?  -  Nov 2, 2006
In 2001, Pharmacia (now Pfizer) introduced rifabutin (Mycobutin), a rifampicin ... In developed markets, rifabutin is used for prevention of TB infection in ... Nature.com

Mycobacterium lentiflavum infection in immunocompetent patient.( …  -  Jan 1, 2005
Susceptibility tests, using proportion methods, showed sensitivity to clarithromycin, ethambutol, isoniazid, streptomycin, rifabutin, cycloserine, ... $4.95 - Emerging Infectious Diseases - ECNext

Mycobacterium kansasii  -  Jun 6, 2006
Por este motivo, si estás recibiendo tratamiento para M. kansasii y anti-VIH, rifabutin es una mejor opción. Sin embargo, también podría ser necesario ... AIDSmeds.com HIV/AIDS Treatment News

Loislaw Federal District Court Opinions - DENT v. ASTRUE (WDTenn. 3-6...  -  Mar 6, 2008
Dent had been taking Bactrim Double Strength and Rifabutin 150 mg for prophylaxis of ... She has some fatigue which may be associated with the rifabutin, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Levofloxacin looks effective for H. pylori.(Clinical Rounds) |...  -  Oct 1, 2005
Article: Rifabutin-based regimens tackle resistant H. ... Family Practice News; May 15, 2006 ; 700+ words ... ... proton pump inhibitor, rifabutin, ... Pay-Per-View - Family Practice News - HighBeam Research

Article: Combo therapy speeds response in psoriasis.(Skin Disorders)(...  -  Apr 15, 2006
Two different rifabutin-based, triple-therapy approaches proved to be safe and effective ... Triple therapy with a proton pump inhibitor, rifabutin ... ... Pay-Per-View - Family Practice News - HighBeam Research

X-Ray - Your Guide to All the Key X-Ray Techniques  -  Sep 12, 2005
Their data on two representatives of each class of rifamycin - rifapentin and rifabutin - reveal that these drugs, remove a key component of bacteria - the ... spectroscopyNOW.com

Pfizer says may win six Japan approvals this year  -  Feb 28, 2008
...that other drugs that may gain approval include Macugen for age-related vision problems and rifabutin for fighting an HIV-related bacterial infection. ... Reuters

Voriconazole (Systemic).(Drug overview)  -  Aug 1, 2006
Rifabutin -- Using this medicine with voriconazole may increase blood levels of rifabutin and decrease blood levels of voriconazole. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Echinocandins offer antifungal therapy with low toxicity, few drug...  -  May 15, 2005
Drugs that affect voriconazole include phenytoin, rifampin, and rifabutin. Other potential interactions include carbamazepine, protease inhibitors, ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Update on Helicobacter pylori treatment.(control of bacterial...  -  Feb 1, 2007
...(43) Regimens that include rifabutin (Mycobutin), 300 mg per day, ... Rifabutin- and furazolidone-based Helicobacter pylori eradication therapies after ... $4.95 - American Family Physician - ECNext

Voriconazole (Systemic).  -  Oct 27, 2005
Rifabutin -- Using this medicine with voriconazole may increase blood levels of rifabutin and decrease blood levels of voriconazole. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

"Mycobacterium tilburgii" infections.(LETTERS)(Letter to the editor)  -  Mar 1, 2006
...clarithromycin, Germany rifabutin (5) M (35) Ethambutol, clarithromycin, Germany rifabutin (12 ([dagger])) M (41) Surgical resection; Germany ethambutol ... Free with registration - Emerging Infectious Diseases - AccessMyLibrary.com

Clarithromycin (Systemic).(Drug overview)  -  May 1, 2006
Rifabutin (eg, Mycobutin) or Rifampin (eg, Rifadin) -- Rifabutin or rifampin may decrease the amount of clarithromycin in the blood Sildenafil (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Fight is on for access to new crohn's treatment  -  Jul 21, 2005
Various medical trials of his Rifabutin and Clarithromycin tonic have failed to ... However, Rifabutin and Clarithromycin are not licensed for use in the ... Pay-Per-View - Aberdeen Press & Journal - Factiva, from Dow Jones

Article: Research Leads to First Treatment for Drug-Resistant HIV. - ...  -  Aug 2, 2006
The possible complications protease inhibitors pose for TB treatment has some clinicians ... take rifabutin so they can take protease inhibitors. ... Pay-Per-View - AScribe Medicine News Service - HighBeam Research

"Mycobacterium tilburgii" infections.(LETTERS)(Letter to the editor)  -  Mar 1, 2006
...clarithromycin, Germany rifabutin (5) M (35) Ethambutol, clarithromycin, Germany rifabutin (12 ([dagger])) M (41) Surgical resection; Germany ethambutol ... $4.95 - Emerging Infectious Diseases - ECNext

Article: Pfizer upbeat on Japan filings HOT STOCKS - International...  -  Feb 29, 2008
...other drugs that might gain approval included Macugen for age- related vision problems and rifabutin for fighting an HIV-related bacterial infection. ... Pay-Per-View - International Herald Tribune - HighBeam Research

Abbott Receives US Food and Drug Administration Approval for New …  -  Nov 12, 2007
...oral contraceptives ("the pill") or the contraceptive patch, Mycobutin(R) (rifabutin), inhaled Flonase(R) (fluticasone), metronidazole, or disulfiram. ... Free with registration - PR Newswire - AccessMyLibrary.com

New Abbott Aluvia® Tablet for Treatment of HIV Available in South...  -  Jun 2, 2008
...phenytoin, phenobarbital), warfarin, certain antibiotics (eg rifabutin, clarithromycin), certain antidepressants (eg trazodone) and voriconazole. ... AllAfrica.com

雅培通过FDA 对其新的低浓度Kaletra(洛匹那韦ï¼?利托那韦)è?¯ç‰‡æ²»ç–—å„¿ç«¥ …  -  Nov 13, 2007
...���孕�或�孕贴片�Mycobutin(R)(利�布汀(rifabutin))��入�Flonase(R)( 氟替��(fluticasone))�甲�唑(metronidazole) 或�硫仑(disulfiram)。 ... 金�界

What role do antibiotics have in the treatment of IBD?  -  Jun 15, 2008
...(2007) Two-year combination antibiotic therapy with clarithromycin, rifabutin, and clofazimine for Crohn's disease. Gastroenterology 132: 2313–2319 ... Nature.com

Mycobacterium avium Complex (MAC)  -  Jun 9, 2005
Rifabutin (Mycobutin®) ha demostrado ser muy efectivo, pero puede tener interacciones negativas con otros medicamentos, especialmente con los inhibidores de ... AIDSmeds.com HIV/AIDS Treatment News

å?£æœ?é?¿å­•藥失效? æœ?抗生素四環素等藥須加戴ä¿?險套  -  Aug 25, 2005
...至於第二類的藥物,如果�是短暫�用,女性應在�藥期間至�藥後7天,請男性戴上�險 套,其中抗�核藥Rifampicin�Rifabutin��酵素的影響較其他藥物更久,因此應延長 ... ettoday.com

Abbott Terima Persetujuan dari Badan Makanan dan Obat AS Untuk …  -  Nov 13, 2007
...(rifabutin), Flonase hisap? (fluticasone), metronidazole, atau disulfiram. Pasien harus berbicara dengan dokter mereka tentang semua obat yang mereka ... ANTARA

Abbott Submits EU and US Regulatory Filings for New Lower-Strength …  -  Jul 20, 2007
...phenytoin, phenobarbital), warfarin, certain antibiotics (ie, rifabutin, clarithromycin), certain antidepressants (ie, trazodone) and voriconazole. ... Free with registration - PR Newswire - AccessMyLibrary.com

Etravirine (TMC125, Intelence) granted accelerated approval in US  -  Jan 21, 2008
In addition, etravirine should not be co-administered with carbamazepine, phenobarbital, phenytoin, rifampin, rifapentine, rifabutin (when part of a regimen ... Aidsmap

Urogenital tuberculosis in a patient with AIDS: an unusual presentatio...  -  Aug 20, 2007
Rifabutin is the preferred choice because of its relatively low risk of drug interaction, but rifampin can be safely used in conjunction with efavirenz, ... Nature.com

Bucking the mainstream on Crohn's: Gastrointestinal doctors claiming...  -  May 16, 2006
Vest sought care in Texas last year from the only physician in the United States who would put her on Borody's triple-drug regimen - rifabutin, ... Free with registration - Newsday - AccessMyLibrary.com

Australians back bacterial theory for bowel disease  -  Jun 1, 2006
Borody has instead concocted a mixture of three antibiotics: rifabutin, clarithromycin and clofazimine, used to treat mycobacterial infections common in ... Nature.com

Ugandan Children Are Among the First to Receive Abbott's Lower- …  -  Dec 1, 2007
...phenytoin, phenobarbital), warfarin, certain antibiotics (ie, rifabutin, clarithromycin), certain antidepressants (eg trazodone) and voriconazole. ... Free with registration - PR Newswire - AccessMyLibrary.com

Australian doc says infection is at root of Crohn's disease  -  Mar 16, 2006
...only the presence of bacteria in Crohn's patients, but that all tend to respond to these three antibiotics: rifabutin, clarythromycin and clofazimine. ... Pay-Per-View - Newsday - ProQuest Archiver

YOUR VIEWS | Article from The Record (Bergen County, NJ) | HighBeam …  -  Feb 14, 2006
Our 22-year-old son with Crohn's disease has been taking two antibiotics (mycobutin-rifabutin and biaxin-clarithromycin) effective against MAP and is now ... Pay-Per-View - The Record - HighBeam Research

Tibotec's Intelence (Etravirine, TMC125) is Approved by FDA  -  Jan 18, 2008
...the antibiotics Rifadin (rifampin), Priftin (rifapentine) and Mycobutin (rifabutin); or products containing St. John's wort (Hypericum perforatum). ... AIDSmeds.com HIV/AIDS Treatment News

Steroid treatment for uveitis needs strict self-regulation  -  Jun 7, 2007
With the possibilities of Behçet's and lymphoma, the diagnosis concluded with rifabutin-induced uveitis. This final rule was: "Always, we have to talk to ... OSN SuperSite

How to take Bortezomib from Consumer Reports Health.  -  Jan 8, 2007
...phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin, Phenytek); mibefradil (no longer available in the US); nefazodone; rifabutin (Mycobutin); ... consumerreports.org

结核æ?†è?Œè€?è?¯åˆ†å­?机ç?†çš„研究进展  -  Aug 10, 2005
...的两ç§?çª?å?˜æœ€å¸¸è§?,约å? æ€»çª?å?˜65%以上[5]。13ï¼…rpoB基因çª?å?˜çš„RFP高度è€?è?¯æ ªä»?对 利ç¦?布ä¸?(rifabutin)æ•?感,æ??示å?¯é‡‡ç”¨åˆ©ç¦?布ä¸?治疗æŸ?些RFPè€?è?¯çš„结核病。 ... æ?œç‹?

Abbott Study Shows Investigational Heat-Stable Norvir(R) Tablet...  -  Aug 8, 2008
Levitra(R) (vardenafil), oral contraceptives ("the pill") or the contraceptive patch, Mycobutin(R) (rifabutin), rifampin, also known as Rimactane(R), ... presseportal.de

How to take Sildenafil from Consumer Reports Health.  -  Jan 12, 2007
Epitol, Tegretol), phenobarbital, and phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); and rifampin (Rifadin, Rimactane). ... consumerreports.org

Antifungal Vfend(R) provides significant cost advantages when used as...  -  Jun 2, 2005
...torsades de pointes), sirolimus, rifampin, rifabutin, carbamazepine, long-acting barbiturates, ergot alkaloids, efavirenz, and ritonavir (400 mg q12h). ... Medical News Today - Medical News Today (press release)

International Approvals: Byetta and Noxafil  -  Nov 28, 2006
Because cimetidine, rifabutin, and phenytoin can decrease posaconazole plasma concentrations, their coadministration should generally be avoided unless the ... Medscape

Pfizer's Vfend equals two-drug candidemia regimen, with fewer serious...  -  Nov 7, 2005
...torsades de pointes), sirolimus, rifampin, rifabutin, carbamazepine, long-acting barbiturates, ergot alkaloids, efavirenz and ritonavir (400 mg q12h). ... Medical News Today - Medical News Today (press release)

HIV-Associated TB: Hit the HIV Early and Hard  -  Feb 14, 2005
In addition, more patients in the second group than in the first used rifabutin as a component of TB treatment (35% vs. 6%). ... Medscape

XDR-TB Rate Holding Steady After Decline  -  Nov 14, 2008
...and 95% of them had drug susceptibility results reported for isoniazid (Nydrazid) and a rifamycin, either rifampin (Rifadin) or rifabutin (Mycobutin). ... MedPage Today

How to take Toremifene from Consumer Reports Health.  -  Jan 1, 2008
...nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); and verapamil (Calan, Covera, Verelan). ... consumerreports.org

TB that developed resistance to every drug kills two in Italy  -  May 21, 2007
She was then referred to a specialist tuberculosis clinic and was treated with a third-line regimen of rifabutin, clofazimine, dapsone, thiacetazon and ... Aidsmap

Estrogens and Progestins Oral Contraceptives (Systemic ).  -  Oct 27, 2005
Dilantin) or Plicamycin (eg, Mithracin) or Primidone (eg, Mysoline) or Rifabutin (eg, Mycobutin) or Rifampin (eg, Rifadin) or Troleandomycin (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Rifaximin (Oral-Local).  -  Jul 28, 2005
Tell your doctor if you have ever had any unusual or allergic reaction to rifaximin, rifampin or rifabutin. Also tell your doctor and pharmacist if you are ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

TradeName : Pangraf, Vingraf, Prograf, Protopic, Tacromus  -  Dec 31, 2008
...methylprednisolone, metoclopramide, nefazodone, nicardipine, nifedipine, omeprazole, oral contraceptives, phenobarbital, phenytoin, rifabutin, rifampin, ... MedIndia

Atovaquone and Proguanil ( Systemic).(Drug overview)  -  May 1, 2006
Rifabutin (eg, Mycobutin) or Rifampin (eg, Rifadin) -- Use of rifampin may decrease the amount of atovaquone in the blood and keep it from working properly ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Fusarium oxysporum pneumonia in an immunocompetent host.(Case …  -  Jun 1, 2006
Mycobacterium avium complex (MAC) was diagnosed, and she was successfully treated with an 18-month course of ethambutol, rifabutin, and clarithromycin. ... Free with registration - Southern Medical Journal - AccessMyLibrary.com

New analysis supports starting with VFEND for life-threatening fungal...  -  Oct 30, 2005
...torsades de pointes), sirolimus, rifampin, rifabutin, carbamazepine, long-acting barbiturates, ergot alkaloids, efavirenz and ritonavir (400 mg q12h). ... Medical News Today - Medical News Today (press release)

Rifampin, Isoniazid, and Pyrazinamide (Systemic).  -  Aug 1, 2006
Trecator-SC), pyrazinamide, niacin (eg, Nicobid, nicotinic acid), rifampin (eg, Rifadin), rifabutin (eg, Mycobutin), or isoniazid (eg, INH, Nydrazid). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Rifampin, Isoniazid, and Pyrazinamide (Systemic).(Drug overview)  -  May 1, 2006
Trecator-SC), pyrazinamide, niacin (eg, Nicobid, nicotinic acid), rifampin (eg, Rifadin), rifabutin (eg, Mycobutin), or isoniazid (eg, INH, Nydrazid). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

New Abbott Aluvia(R) Tablet for Treatment of HIV Available in South …  -  Mar 6, 2008
...phenytoin, phenobarbital), warfarin, certain antibiotics (eg, rifabutin, clarithromycin), certain antidepressants (eg, trazodone) and voriconazole. ... ITNews

Progestins --For Noncontraceptive Use (Systemic).  -  Oct 27, 2005
Aminoglutethimide (e.g., Cytadren) or Carbamazepine (e.g., Tegretol) or Phenobarbital or Phenytoin (e.g., Dilantin) or Rifabutin (e.g., Mycobutin) or ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Fludrocortisone (Systemic).  -  Oct 27, 2005
Viramune) or Phenylbutazone (eg, Butazolidin) or Phenytoin (eg, Dilantin) Primidone (eg, Mysoline) or Rifabutin (eg, Mycobutin) or Rifampin (eg, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Rifapentine (Systemic).(Drug overview)  -  May 1, 2006
Tell your doctor if you have ever had any unusual or allergic reaction to rifabutin (eg, Mycobutin), rifampin (eg, Rifadin), or rifapentine. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Sirolimus (Systemic).(Drug overview)  -  Aug 1, 2006
Carbamazepine (eg, Tegretol) or Rifabutin (eg, Mycobutin) or Rifampin (eg, Rifadin) or Rifapentine (eg, Priftin) St. John's wort -- May decrease the effects ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Interaction with other medicines  -  Feb 5, 2008
An alternative (except when taking rifampicin, or rifabutin) is to take two COC pills a day. However, this is an unlicensed use of the COC pill and it ... NHS Choices

Rifapentine (Systemic).  -  Feb 1, 2006
Tell your doctor if you have ever had any unusual or allergic reaction to rifabutin (eg, Mycobutin), rifampin (eg, Rifadin), or rifapentine. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

How to take Fentanyl Buccal (Transmucosal) from Consumer Reports …  -  Jan 1, 2008
...phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate); sedatives; sleeping pills; and tranquilizers. ... consumerreports.org

Tuberculosis | Practice | Nursing Times  -  Jan 10, 2006
Rifabutin, cycloserine, capreomycin and streptomycin can also be used if there is antibiotic resistance. - Once treatment has started, people normally ... Nursing Times

How to take Erlotinib from Consumer Reports Health.  -  Jan 12, 2008
...lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), and rabeprazole (AcipHex); rifabutin (Mycobutin); rifampin (Rifadin, ... consumerreports.org

2005 Medical Student Clinical Vignette Abstract Winners  -  May 2, 2005
Empiric treatment of immune-reconstitution MAC with clarithromycin, rifabutin, and ethambutol, was begun, and the fever and abdominal pain resolved. ... ACP Observer

How to take Temsirolimus from Consumer Reports Health.  -  Jan 1, 2008
Tegretol), phenobarbital (Luminal),and phenytoin (Dilantin, Phenytek); medications to lower cholesterol and lipids; nefazodone; rifabutin (Mycobutin); ... consumerreports.org

Brand Names/Synonyms:
Rifabutin is also known by the following brand names and/or synonymsANSAMYCIN; Alfacid; Ansamycin; Ansatipin; Ansatipine; Antibiotic Lm 427; Mycobutin; RBT; RIFABUTIN; Rifabutin; Rifabutina [Spanish]; Rifabutine [French]; Rifabutinum [Latin]

Drug Category:
Rifabutin is categorized under the following by the FDA: Antibiotics; Anti-bacterial Agents; Antituberculosis Agents; ATC:J04AB04

Dosage Forms:
CAPSULE

Absorption:
Following a single oral dose of 300 mg to nine healthy adult volunteers, rifabutin was readily absorbed from the gastrointestinal tract. Absolute bioavailability averaged 20%.

Interactions:
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Chemical IUPAC Name:
(9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6,16,18,20-Tetrahydroxy-1'-isobutyl-14-methoxy-7,9,15,17,19,21,25-hepta-methyl-spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo-[2',3':7,8]-naphth[1,2-d]imidazol-2,4'-piperidin]-5,10,26-(3H,9H)-trione 16-acetate





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