Rifater

This page contains recent news articles, when available, and an overview of Rifater but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Rifater
(when available)

Pharmacology and use:
Rifampin is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. It is bactericidal and has a very broad spectrum of activity against most gram-positive and gram-negative organisms (including Pseudomonas aeruginosa) and specifically Mycobacterium tuberculosis. Because of rapid emergence of resistant bacteria, use is restricted to treatment of mycobacterial infections and a few other indications. Rifampin is well absorbed when taken orally and is distributed widely in body tissues and fluids, including the CSF. It is metabolized in the liver and eliminated in bile and, to a much lesser extent, in urine, but dose adjustments are unnecessary with renal insufficiency. For the treatment of Tuberculosis and Tuberculosis-related mycobacterial infections

Mechanism Of Action:
Rifampin acts via the inhibition of DNA-dependent RNA polymerase, leading to a suppression of RNA synthesis and cell death.

News Articles on Rifampin

Generic ingredients: Rifampin, Isoniazid, Pyrazinamide  -  Dec 1, 2005
Rifater is a combination antibiotic used to treat the initial phase of ... Isoniazid, one of the components of Rifater, sometimes causes liver damage. ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

How to take Pioglitazone from Consumer Reports Health.  -  Jan 9, 2007
...and injections), ketoconazole (Nizoral), midazolam, montelukast (Singulair), nifedipine (Procardia), and rifampin (Rifadin, Rifater, in Rifamate). ... consumerreports.org

Article: Marion sounds the clarion - New Straits Times | HighBeam …  -  Mar 25, 2007
Drug Application in the United States for Rifater(R ... therapy for ... Rifater combines the ... rifampin, discovered by Marion Merrell Dow and marketed . ... Pay-Per-View - New Straits Times - HighBeam Research

High dose of old antibiotic offers potent TB treatment  -  Dec 18, 2007
Some of them were treated with the standard DOTS regimen, daily Rifater, while others took rifapentine in place of rifampin. Rifapentine, in daily amounts ... thecheers.org

Older Antibiotic Gains New Respect as Potent Treatment for Tuberculosi...  -  Dec 17, 2007
Some were treated with the standard DOTS regimen, daily Rifater, while others took rifapentine in place of rifampin. Rifapentine, in daily amounts similar ... Free with registration - Ascribe Higher Education News Service - AccessMyLibrary.com

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 21, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Blood Weekly - Factiva, from Dow Jones

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 22, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Older Antibiotic Gains New Respect as Potent Treatment for Tuberculosi...  -  Dec 14, 2007
Some were treated with the standard DOTS regimen, daily Rifater, while others took rifapentine in place of rifampin. Rifapentine, in daily amounts similar ... newswise.com

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 18, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Respiratory Therapeutics Week - Factiva, from Dow Jones

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 23, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Güney Kıbrıs'tan ülkemize kaçak getirtildiÄŸi tahmin edilen 'Champion'...  -  Feb 9, 2008
Tunçalın Av Pazarı sahibi Ahmet Tunçalın, 'Champion' marka köpek mamalarını 'Rifater Limited Şirketi'nden resmi bir faturayla aldıklarını kaydetti. ... Kıbrıs Gazetesi

University of Stellenbosch, Tygerberg; Melatonin prevents free...  -  Apr 20, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Article: Dow Closes Above 13,000 on Earnings Data - AP Online | …  -  Apr 26, 2007
Drug Application in the United States for Rifater(R), a ... tuberculosis. ... Rifater combines the ... discovered by Marion Merrell Dow and marketed as a ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 19, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

isoniazid | Definition of isoniazid | HighBeam.com: Online Dictionary  -  Jul 12, 2006
Article: RIFATER, NEW TRIPLE COMBINATION THERAPY, NOW AVAILABLE TO . ... KANSAS CITY, Mo., Oct. 17 /PRNewswire/ -- Rifater (rifampin 120 mg, isoniazid 50 mg ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Article: Dow Closes Above 13,000 on Earnings Data - AP Online | …  -  Apr 25, 2007
Drug Application in the United States for Rifater(R), a ... tuberculosis. ... Rifater combines the ... discovered by Marion Merrell Dow and marketed as a ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 18, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Hematology Week - Factiva, from Dow Jones

Tuberculosis, a neglected opportunity?  -  Nov 2, 2006
It is supplied as a single agent (Rifadin), and in fixed combination with isoniazid or a combination of isoniazid (Rifanah) and pyrazinamide (Rifater); ... Nature.com

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 18, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 19, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Tuberculosis Treatment; Melatonin prevents free radical/MADD metabolic...  -  Apr 18, 2005
..."A combined anti-TB drug, Rifater, consisting of 12.0 mg rifampicin, 0.8 mg isoniazid, and 23.0 mg pyrazinamide and 18.56 mcg melatonin/kg body weight per ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Abbott Study Shows Investigational Heat-Stable Norvir(R) Tablet...  -  Aug 8, 2008
...rifampin, also known as Rimactane(R), Rifadin(R), Rifater(R) or Rifamate(R); inhaled Flonase(R) (fluticasone), metronidazole or disulfiram. ... presseportal.de

How to take Raltegravir from Consumer Reports Health.  -  Jan 1, 2008
Be sure to mention any of the following: rifampin (Rifadin, Rifater, Rimactane), or cholesterol-lowering medications (statins) such as atorvastatin ... consumerreports.org

Abbott Statement on Advancing Pediatric HIV Treatment in Developing …  -  Mar 13, 2006
Lopinavir/ritonavir should also not be taken with rifampin, also known as Rimactane(R), Rifadin(R), Rifater(R), or Rifamate(R), Flonase(R), Mevacor(R), ... $4.95 - PR Newswire - ECNext

How to take Haloperidol from Consumer Reports Health.  -  Jan 11, 2008
...methyldopa; moxifloxacin (Avelox); narcotic medications for pain; pimozide (Orap); procainamide ; quinidine ; rifampin (Rifater, Rifadin); sedatives; ... consumerreports.org

ABBOTT STATEMENT ON ADVANCING PEDIATRIC HIV TREATMENT.  -  Mar 14, 2006
Lopinavir/ritonavir should also not be taken with rifampin, also known as Rimactane(R), Rifadin(R), Rifater(R), or Rifamate(R), Flonase(R), Mevacor(R), ... $4.95 - AsiaPulse News - ECNext

Abbott Receives US Food and Drug Administration Approval for New …  -  Nov 12, 2007
KALETRA must not be taken with rifampin, also known as Rimactane(R), Rifadin(R), Rifater(R), or Rifamate(R); St. John's wort (Hypericum perforatum); ... Free with registration - PR Newswire - AccessMyLibrary.com

雅培通过FDA 对其新的低浓度Kaletra(洛匹那韦ï¼?利托那韦)è?¯ç‰‡æ²»ç–—å„¿ç«¥ …  -  Nov 13, 2007
KALETRA �得与利�平(rifampin)(�Rimactane(R)�Rifadin(R)�Rifater(R) 或Rifamate(R));圣约翰�(St. John''s wort)(贯�连翘(Hypericum ... 金�界

hoyInversión: Actualidad económica, dinero, bolsa, cotizaciones y …  -  Nov 13, 2007
KALETRA no deberá tomarse con rifampin, también conocido como Rimactane(R), Rifadin(R), Rifater(R), o Rifamate(R); Hierba de San Juan (Hypericum perforatum) ... Finanzas.com

Abbott Terima Persetujuan dari Badan Makanan dan Obat AS Untuk …  -  Nov 13, 2007
KALETRA tidak boleh dikonsumsi dengan rifampin, dikenal juga sebagai Rimactane (R), Rifadin (R), Rifater (R), St. John's wort (Hypericum perforatum): ... ANTARA

Abbott Receives FDA Approval for New Kaletra(R) (Lopinavir/Ritonavir)...  -  Oct 31, 2005
Rimactane(R), Rifadin(R), Rifater(R), or Rifamate(R), Flonase(R), Mevacor(R), Zocor(R) or products containing St. John's wort (Hypericum perforatum). ... Free with registration - PR Newswire - AccessMyLibrary.com

How to take Exemestane from Consumer Reports Health.  -  Jan 3, 2007
...and rifampin (Rifadin, in Rifater, in Rifamate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. ... consumerreports.org

Knowledge - Tuberculosis treatment: managing non-adherence  -  Feb 20, 2007
For example, Rifadin, Rifinah, Rifater all have similar-sounding names but different ingredients. For this reason patients with the infection should be ... Nursing Times

DNA vaccine for TB prevents recurrence  -  Feb 11, 2005
...and treated them with the anti-tubercular agents isoniazid and pyrazinamide (Rifater) five times in the first four to 16 weeks after infection. ... Pay-Per-View - GP - Factiva, from Dow Jones

Press Release: TB, Other Drug-Resistant Diseases on the Rise in the …  -  Jun 6, 2007
Rifater combines the ... regimens for treating TB call for various combinations ... stem the resurgence of TB," said Fred W. Lyons ... these patients. ... Pay-Per-View - PR Newswire - HighBeam Research

Abbott krijgt goedkeuring van de Food and Drug Administration voor …  -  Nov 13, 2007
KALETRA moet niet worden ingenomen samen met rifampin, ook bekend als Rimactane(R), Rifadin(R), Rifater(R), of Rifamate(R); Sint- Janskruid (Hypericum ... Hiv Vereniging Nederland

Brand Names/Synonyms:
Rifater is also known by the following brand names and/or synonymsArchidyn; L-5103 Lepetit; R/AMP; RAMP; RFP; Ramp; Rfamipicin; Rifa; Rifadin; Rifadin Iv; Rifadine; Rifagen; Rifaldazin; Rifaldazine; Rifaldin; Rifamate; Rifampicin; Rifampicin Sv; Rifampin; Rifamycin; Rifamycin Amp; Rifaprodin; Rifater; Rifoldin; Rifoldine; Riforal; Rimactan; Rimactane; Rimactin; Rimazid; Rofact; Tubocin

Drug Category:
Rifater is categorized under the following by the FDA: Leprostatic Agents; Antibiotics; Antituberculosis Agents; ATC:J04AB

Dosage Forms:
CAPSULE

Absorption:
Well absorbed from gastrointestinal tract

Interactions:
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Chemical IUPAC Name:
{2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,} 1-b\]furan-1,11(2H)-dione, {22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-,} 21-acetate





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