Risedronate

This page contains recent news articles, when available, and an overview of Risedronate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Risedronate
(when available)

Pharmacology and use:
Risedronate is a pyridinyl bisphosphonate that inhibits osteoclast-mediated bone resorption and modulates bone metabolism and is indicated for the treatment and prevention of osteoporosis in postmenopausal women. For the treatment of Paget's disease of the bone (osteitis deformans); Postmenopausal and glucocorticoid-induced osteoporosis

Mechanism Of Action:
The action of Risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Risedronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

News Articles on Risedronate

Options for Bone Loss, but No Magic Pill  -  ‎Jan 4, 2010‎
Likewise with a sister drug, Actonel (risedronate). A reluctance on the part of many patients to adhere to a daily or weekly regimen led to the development ... New York Times

Warner Chilcott Affirms Global Marketing and Collaboration Agreement With ...  -  ‎Dec 15, 2009‎
...between a P&G subsidiary acquired by Warner Chilcott and Sanofi relating to the development and sale of risedronate products (including Actonel®). ... CNNMoney.com (press release)

This Week in Health  -  ‎Dec 11, 2009‎
They include alendronate (Fosamax), risedronate (Actonel) and others. Women take them for osteoporosis. This condition causes thin, brittle bones. ... Intelihealth.com

Comment on "A Comparison of Prediction Models for Fractures in Older Women"  -  ‎Dec 14, 2009‎
10 but a trial of risedronate in older women selected on the basis of fracture risk factors was effective only in those with osteoporotic T scores. ... Archives of Internal Medicine

Legal fight fails as NICE stands firm on osteoporosis guidance  -  ‎Dec 10, 2009‎
...with Procter & Gamble's Didronel (etidronate) and Actonel (risedronate) as first alternatives if the patient is intolerant to Fosamax. ... Pharma Times

NICE guidelines limit options for low cost osteoporosis drugs  -  ‎Dec 13, 2009‎
There are alternatives for those who cannot take alendronate (etidronate, risedronate, or strontium ranelate or, for secondary prevention only, ... News-Medical.net

Warner Chilcott Considers Potential Repurchase or Redemption of 8.75% Senior ...  -  ‎Dec 14, 2009‎
...acquired by Warner Chilcott and Sanofi-Aventis US LLC ("Sanofi") relating to the development and sale of risedronate products (including Actonel®). ... Melodika.net

NICE Guidelines Ration Affordable Osteoporosis Drugs  -  ‎Dec 12, 2009‎
There are alternatives for those who cannot take alendronate (etidronate, risedronate, or strontium ranelate or, for secondary prevention only, ... Medical News Today (press release)

Acido zoledronico o risedronato per l'osteoporosi da steroidi  -  ‎Dec 26, 2009‎
Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON): a multicentre, double-blind, double-dummy, ... Pillole.org

Health Alliance Announces Promising Nine-Month Results from First Ever Outcome ...  -  ‎Oct 29, 2009‎
About Actonel (risedronate sodium) Tablets Actonel is indicated for the treatment and prevention of osteoporosis in postmenopausal women. ... Reuters

Medicine charges to rise  -  ‎Nov 6, 2009‎
The other two groups, risedronate and alendronate, treat osteoporosis and Paget disease. The brand name for risedronate is Actonel. ... Courier Mail

What is Paget Disease?  -  ‎Nov 7, 2009‎
Biphosphonates include risedronate, alendronate, and pamidronate. Long-term treatment may be needed if the disease is severe, especially if the person has ... 24 Medica

Warner Chilcott acquires global pharmaceuticals business of Procter & Gamble  -  ‎Oct 30, 2009‎
...including Asacol HD (mesalamine) delayed-release tablets for ulcerative colitis, Actonel (risedronate sodium) for osteoporosis, and the co-promotion ... Trading Markets (press release)

Academic made 'untrue' declaration about 'full access' to research material ...  -  ‎Nov 10, 2009‎
The paper, “Relationship of early changes in bone resorption to the reduction in fracture risk with risedronate�, was published in the Journal of Bone and ... Times Higher Education

New Interactive 3D Molecular Images in Scientific Articles  -  ‎Oct 19, 2009‎
...known as FDPS, using iSee, they understood immediately how their drug Actonel (also known as risedronate) worked by binding to the protein. ... ScienceBlogs (blog)

건강한 중년, 아름다운 여성  -  ‎Nov 9, 2009‎
...골다공ì¦?ì?˜ ì?¼ì°¨ì ?ì?¸ 치료제로 í?”히 사용하는 것ì?€ 주로 골í?¡ìˆ˜ë¥¼ 억제하는 약물로 알렌드로네ì?´íЏ(alendronate), 리세드로네ì?´íЏ(risedronate), ... 쿠키뉴스

æ—¥ 제네릭 시장 '외ìž?사 진출러시'  -  ‎Nov 2, 2009‎
...ìš°ì„  ë‚´ë…„ì—? '노보믹스'(NovoMix, insulin aspart), '악토넬'(Actonel, risedronate), '세레벤트'(Serevent, salmeterol), '프로그ëž?'(Prograf, tacrolimus)ì?˜ 특허가 ... 디지틀보사

… & Gamble, Sanfi Aventis report positive phase III data on 'risedron...  -  Jun 5, 2006
...'In the trial ... patients treated with risedronate experienced statistically significant ... They added that: 'Overall, risedronate was well-tolerated, ... Forbes

Drug Shields Parkinson's Patients Against Fracture  -  Mar 19, 2007
Half of them were given risedronate and vitamin D2, while the other half ... The men taking risedronate were three times less likely to suffer a hip ... ABC News

Can treatment with risedronate benefit patients with knee osteoarthrit...  -  Jan 17, 2007
Bingham CO et al. (2006) Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression ... Nature.com

How effective is risedronate in preventing bone loss in patients on...  -  May 12, 2008
Oral bisphosphonates have proven to be an effective strategy for the prevention and treatment of glucocorticoid-induced osteoporosis; however, ... Nature.com

Bone drug works for breast cancer survivors  -  Jun 18, 2008
NEW YORK (Reuters Health) - Risedronate, better known by the brand name Actonel ... To investigate the usefulness of risedronate in combating these effects, ... Reuters

… of zoledronic acid more effective than oral risedronate for the...  -  Nov 29, 2005
...(2005) Comparison of a single infusion of zoledronic acid with risedronate for Paget's disease. N Engl J Med 353: 898–908 PubMed ... Nature.com

Weekly alendronate versus risedronate for postmenopausal osteoporosis...  -  Aug 19, 2006
Bonnick S et al. (2006) Comparison of weekly treatment of postmenopausal osteoporosis with alendronate versus risedronate over two years. ... Nature.com

… single infusion of zoledronic acid superior to risedronate for the...  -  Dec 14, 2005
The oral bisphosphonate risedronate is currently used to treat patients with ... To compare the effects of zoledronic acid with those of risedronate on ... Nature.com

Is risedronate or alendronate more effective at preventing nonvertebra...  -  Jul 1, 2007
Silverman SL et al. (2007) Effectiveness of bisphosphonates on nonvertebral and hip fractures in the first year of therapy: the risedronate and alendronate ... Nature.com

Study says Actonel almost halves risk of breaking a hip  -  Nov 17, 2006
The rapid onset of fracture reduction observed for risedronate in this study is consistent with results from randomised clinical trials of risedronate, ... Forbes

Novartis says Aclasta better at boosting bone mass  -  Apr 11, 2008
A once-yearly infusion of Aclasta showed benefits versus the daily pill Actonel, also known as risedronate, in patients taking steroids, which are widely ... Reuters

Science File; Drug Proves Effective Against Paget's Disease  -  Sep 3, 2005
And whereas the effects of risedronate wore off in one-quarter of the volunteers after one year, that happened in less than 1% of the zoledronic acid ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

… Once Monthly Dosing Regimen of Risedronate to Treat Postmenopausal...  -  Sep 19, 2007
In the non-inferiority study comparing risedronate 150 mg once monthly to ... "Risedronate is already approved to reduce the risk of both spinal and ... Genetic Engineering News - Genetic Engineering News (press release)

Aclasta Superior to Risedronate for Paget's Disease of the Bone in...  -  Aug 31, 2005
BASEL, Switzerland, Aug. 31, 2005 (PRIMEZONE) -- A head-to-head study published in The New England Journal of Medicine (NEJM)(1) showed that a single dose ... primezone.com

Risedronate Oral : User Ratings covering uses, effectiveness,...  -  May 6, 2008
I discontinued it as it caused stomach ulcers, even tho I followed all the directions. Because of bleeding, it also lowered my red blood count. ... WebMD

Israeli drug maker says federal regulators granted final marketing …  -  Oct 9, 2007
Specifically, the US Food and Drug Administration approved Teva's abbreviated new drug application for risedronate sodium tablets at 5, 30 and 35 milligram ... Ynetnews

Risedronate (Systemic).  -  Feb 1, 2006
Risedronate ( ris-ED-roe-nate) is used to prevent and treat osteoporosis (thinning of bone) in women after menopause. It may also be used in men and women ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Risedronate (Systemic).  -  Jul 28, 2005
Risedronate ( ris-ED-roe-nate) is used to prevent and treat osteoporosis (thinning of bone) in women after menopause. It may also be used in men and women ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Risedronate for the Prevention of Hip Fractures: Concern About...  -  Mar 12, 2007
With concern, we read the trials conducted by Sato and colleagues comparing risedronate sodium with placebo in male patients with stroke 1 and female ... Archives of Internal Medicine

Risedronate gains approval for male osteoporosis.(Endocrinology)( …  -  Sep 15, 2006
The Food and Drug Administration has given the nod to oral rise-dronate sodium (Actonel) for the treatment of idiopathic osteoporosis in men following the ... $4.95 - Internal Medicine News - ECNext

Risedronate Reduces Bone Mass Loss in Breast Cancer Patients After …  -  May 9, 2008
By Crina Frincu-Mallos, PhD. WASHINGTON, DC -- May 9, 2008 -- Risedronate therapy appears to prevent bone loss in premenopausal and newly menopausal women ... DG News

Risedronate in the elderly  -  Aug 24, 2005
Tagawa, Japan - A new study in elderly women with Alzheimer's disease (AD), which shows that treatment with risedronate (Actonel, Aventis) and vitamin-D ... Medscape

Risedronate Counteracts Bone-Depleting Effects of Aromatase Inhibitors  -  Sep 24, 2007
September 24, 2007 (Honolulu) — Not only is aromatase inhibitor–induced damage to bone corrected, but bone mineral density (BMD) is improved to ... Medscape

… provides more improvement in bone mineral density than risedronate  -  Sep 5, 2006
..."Significantly more alendronate than risedronate patients had measured BMD increases of 0% or more and 3% or more at all BMD sites (p<0.001), ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Risedronate Prevents Bone Loss in Early Postmenopausal Women: a …  -  Sep 18, 2005
Objectives To assess the efficacy and tolerability of risedronate, a pyridinyl bisphosphonate, in preventing loss of bone mineral density (BMD) of the ... RedOrbit

… Better for Bone Remodelling Than Risedronate in Glucocorticoid...  -  Jun 15, 2008
By Jill Stein. PARIS -- June 15, 2008 -- In patients with glucocorticoid-induced osteoporosis, a single 5-mg zoledronic-acid infusion is faster and more ... DG News

P&G, Sanofi win FDA OK for Actonel extension  -  Aug 14, 2006
Risedronate, the generic name of the drug produced by Procter & Gamble Pharmaceuticals and Sanofi-Aventis US, (NYSE: SNY) proved effective for men with the ... Bizjournals.com

Drug slows bone loss after breast cancer, Pitt finds  -  Sep 18, 2007
Breast cancer survivors who took a weekly dose of risedronate, ... However, half took 35 milligrams of risedronate once a week while others took a placebo. Pittsburgh Post-Gazette - Pittsburgh Post Gazette

… Shows Once-Yearly Reclast Better than Risedronate at Increasing...  -  Apr 11, 2008
Study Shows Once-Yearly Reclast Better than Risedronate at Increasing Bone Mass in Patients With Osteoporosis Caused by Glucocorticoids. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Alendronate and risedronate compared in BMD study.(Rheumatology)( …  -  Jan 15, 2005
SEATTLE -- Alendronate appears slightly more effective than risedronate at increasing bone mineral density, according to the results of a head-to-head trial ... Free with registration - Internal Medicine News - AccessMyLibrary.com

RISEDRONATE (Oral route) - res-ED-roe-nate.(Drug overview)  -  May 1, 2007
Risedronate is used to prevent and treat osteoporosis (thinning of bone) in women after menopause. This medicine may also be used to increase bone mass in ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Preventive Effect of Risedronate on Bone Loss in Men Receiving …  -  Jan 14, 2008
Androgen-deprivation therapy for prostate cancer decreases bone mineral density and increases the risk of fracture. The effect of risedronate, ... UroToday International Journal

Osteoporosis; Cost-effectiveness of risedronate assessed  -  Jan 1, 2005
2005 JAN 1 - (NewsRx.com & NewsRx.net) -- A recent study analyzed the cost-effectiveness of risedronate (Actonel; Procter & Gamble) for preventing vertebral ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Once-Monthly Risedronate Effective Against Osteoporosis  -  Nov 13, 2007
The supporter had no role in selecting the study or interview sources for news coverage, and it did not review or approve the news article before ... Medscape

… provides more improvement in bone mineral density than risedronate  -  Sep 7, 2006
..."Significantly more alendronate than risedronate patients had measured BMD increases of 0% or more and 3% or more at all BMD sites (p<0.001), ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

… for Once Monthly Dose of Risedronate to Treat Postmenopausal …  -  Jan 14, 2008
Phase III Data Published for Once Monthly Dose of Risedronate to Treat Postmenopausal Osteoporosis. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

High-Dose Risedronate (Actonel) Appears to Delay Joint Destruction in...  -  Nov 18, 2005
By Bruce Sylvester. SAN DIEGO, CA -- November 18, 2005 -- High doses of the osteoporosis drug risedronate (Actonel) appears to delay joint destruction, ... DG News

Risedronate induced transient ocular myasthenia.(Letter)(Case study)  -  Oct 1, 2007
We present a case of ocular myasthenia gravis induced by risedronate therapy for osteoporosis which has not been reported elsewhere. ... Free with registration - Journal of Postgraduate Medicine - AccessMyLibrary.com

Osteoporosis; Data presented on 5 years of treatment with risedronate  -  Mar 8, 2005
2005 MAR 8 - (NewsRx.com & NewsRx.net) -- Data from 5 years of risedronate treatment in postmenopausal women recently were reported in the journal Calcified ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Alendronate beats risedronate in increasing BMD.(Gynecology) |...  -  Mar 1, 2006
Alendronate beats risedronate in increasing BMD.(Gynecology) ... find OB GYN News articles. SAN DIEGO -- Postmenopausal women with low bone density who ... Pay-Per-View - OB GYN News - HighBeam Research

Monthly doses of drug 'could be effective for people with osteoporosis...  -  Jan 15, 2008
A new study has suggested that a monthly 150mg dose of the bone-building drug risedronate could be effective for the treatment of postmenopausal ... Arthritis Research Campaign

Osteoporosis; Data presented on 5 years of treatment with risedronate  -  Mar 7, 2005
2005 MAR 7 - (NewsRx.com & NewsRx.net) -- Data from 5 years of risedronate treatment in postmenopausal women recently were reported in the journal Calcified ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Risedronate reduces hip fractures in older men after stroke.(Brief...  -  Feb 1, 2006
Sato Y, Iwamoto J, Kanoko T, Satoh K, Mitate Hospital, Tagawa, Japan, and other centers. Risedronate sodium therapy for prevention of hip fracture in men 65 ... $4.95 - Journal of Musculoskeletal Medicine - ECNext

Japan approves once-weekly risedronate.  -  Apr 30, 2007
The Japanese Ministry of Health, Labour and Welfare approved Actonel and Benet 17.5 mg tablets, both once-weekly formulations of risedronate sodium hydrate ... $4.95 - Pharma Marketletter - ECNext

Risedronate prevents bone loss and periodontal disease  -  Dec 7, 2005
Drugs that reverse and prevent bone loss due to osteoporosis also significantly ward off periodontal disease, according to a graduate of the Case Western ... News-Medical.net

Risedronate for the Prevention of Hip Fractures: Concern About...  -  Mar 12, 2007
Although it was described that the study was done in a single hospital, I requested my physician colleagues of other nearby hospitals to participate in the ... Archives of Internal Medicine

Article: Risedronate gains approval for treating osteoporosis in...  -  Sep 15, 2006
Risedronate gains approval for treating osteoporosis in men.(News)(Brief article) ... find Family Practice News articles. The Food and Drug Administration ... Pay-Per-View - Family Practice News - HighBeam Research

Menopause; Risedronate proves to be effective as anti-osteoporotic …  -  Oct 27, 2005
2005 OCT 27 - (NewsRx.com) -- Risedronate proves to be effective as an anti-osteoporotic treatment in women with IBD in remission. ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

… & Alternative Medicine; Risedronate and calcitriol improve...  -  Apr 26, 2006
2006 APR 26 - (NewsRx.com) -- Both risedronate and calcitriol treatment increased the maximum load and braking energy of cancellous bone in rats with ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Drug Helps Prevent Hip Fractures in Parkinson Disease  -  Mar 21, 2007
Half of the group received the drug risedronate and vitamin D2. ... The study found the men taking risedronate were three times less likely to sustain a hip ... emaxhealth.com

Menopause; Risedronate proves to be effective as anti-osteoporotic …  -  Oct 28, 2005
2005 OCT 28 - (NewsRx.com) -- Risedronate proves to be effective as an anti-osteoporotic treatment in women with IBD in remission. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Weekly Dose of Osteoporosis Drug Prevents Bone Loss Associated with …  -  Sep 19, 2007
Breast cancer survivors who took a weekly dose of risedronate, ... However, half took 35 milligrams of risedronate once a week while others took a placebo. ... webwire.com

In brief: Risedronate may be more effective.(preventing fractures in ...  -  Dec 2, 2006
Risedronate may be more effective than alendronate in preventing fractures in women with osteoporosis, a large retrospective study has revealed. $4.95 - Chemist & Druggist - ECNext

Alendronate and risedronate compared in BMD study.(Rheumatology)( …  -  Jan 15, 2005
Alendronate and risedronate compared in BMD study.(Rheumatology)(bone mineral density) ... find Internal Medicine News articles. Pay-Per-View - Internal Medicine News - HighBeam Research

A Once-weekly Formulation of Risedronate Sodium Hydrate, an …  -  Apr 18, 2007
Tokyo, Apr 18, 2007 - (JCN Newswire) - Tokyo, Japan, Apr 18, 2007 - (JCN Newswire) - Ajinomoto Co., Inc. ("Ajinomoto", President and CEO: Norio Yamaguchi, ... japancorp.net

Risedronate versus Alendronate study  -  Apr 3, 2007
The largest retrospective, observational study comparing two osteoporosis therapies on the basis of fracture reduction was presented at the Seventh European ... News-Medical.net

Effects of Risedronate on Bone Density in Anorexia Nervosa  -  Jul 1, 2007
Karen K. Miller, Kelly A. Grieco, Jean Mulder, Steven Grinspoon, Diane Mickley, Revital Yehezkel, David B. Herzog and Anne Klibanski ... Journal of Clinical Endocrinology and...

Alendronate edged risedronate in BMD trial, but some skeptical.( …  -  Feb 1, 2005
SEATTLE -- Alendronate appears slightly more effective than risedronate at increasing bone mineral density, according to the results of a head-to-head trial ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

Actonel ® (risedronate sodium) Procter & Gamble (NYSE: PG) Sanofi-av ...  -  Jun 11, 2007
Actonel ® (risedronate sodium) Procter & Gamble (NYSE: PG) Sanofi-aventis Paris (EURONEXT: SAN) New York (NYSE: SNY). ... Gerson Lehrman Group

Alendronate edged risedronate in BMD trial, but some skeptical.( …  -  Feb 1, 2005
Alendronate edged risedronate in BMD trial, but some skeptical.(Musculoskeletal Disorders)(bone mineral density) ... find Family Practice News articles. Pay-Per-View - Family Practice News - HighBeam Research

Effect of Teriparatide Compared to Risedronate on Back Pain in Women ...  -  Apr 20, 2007
The purpose of the study is to determine if daily teriparatide reduces back pain more effectively than weekly risedronate in postmenopausal women with ... Virtual Medical Centre - The Virtual Medical Centre

… BONE TURNOVER MARKERS ON PERSISTENCE WITH RISEDRONATE …  -  Jan 17, 2007
Intervention: Calcium 500 mg/d, vitamin D 400 IU/d, and risedronate 5 mg/d for 1 year. Centers were randomized to reinforcement (RE+) or no reinforcement ... Journal of Clinical Endocrinology and...

Alendronate and Risedronate: Reports of Severe Bone, Joint, and...  -  Feb 14, 2005
The oral bisphosphonate alendronate sodium (Fosamax; Merck & Co Inc, Whitehouse Station, NJ) was first approved for osteoporosis by the Food and Drug ... Archives of Internal Medicine

Press Release: Risedronate Reduced Risk of Fracture Among …  -  Sep 17, 2007
Risedronate Reduced Risk of Fracture Among Osteoporotic Postmenopausal Women with History of Hip Fracture. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Risedronate gains approval for male osteoporosis.(Endocrinology)( …  -  Sep 15, 2006
Risedronate gains approval for male osteoporosis.(Endocrinology)(Clinical report) ... find Internal Medicine News articles. The Food and Drug Administration ... Pay-Per-View - Internal Medicine News - HighBeam Research

Ajinomoto, Takeda Submit Additional Indication for Risedronate Sodium...  -  Jul 31, 2007
Labor and Welfare in Japan to seek marketing approval of risedronate sodium hydrate for the treatment of Paget's disease as an orphan drug. ... FDA news - FDA news (subscription)

Risedronate averts breast cancer-related bone loss  -  Feb 7, 2007
Aggressive breast cancer treatment offers you the hope of living a long, healthy life after treatment. But some breast cancer treatments may speed up bone ... Breastcancer.org

Novartis receives European marketing authorization for Aclasta®  -  Apr 25, 2005
However, oral risedronate requires daily administration for two months and ... Zoledronic Acid Produces Greater And Faster Efficacy Versus Risedronate in ... i-newswire.com

Alendronate better than risedronate at increasing BMD.(Meeting …  -  Jun 1, 2005
Weekly treatment with alendronate is more effective in building bone in the hip and spine than weekly risedronate, according to a new head-to-head study of ... Pay-Per-View - Contemporary OB/GYN - Factiva, from Dow Jones

Article: Alendronate bests risedronate for raising BMD in older...  -  Apr 1, 2006
Alendronate bests risedronate for raising BMD in older women.(Endocrinology)(bone mineral density) ... find Internal Medicine News articles. Pay-Per-View - Internal Medicine News - HighBeam Research

Zoledronic outperforms risedronate in Novartis-funded Dutch trials.(Br...  -  Oct 10, 2005
In studies carried out at the Institute for Medical Technology Assessment, in Rotterdam, the Netherlands, the efficacy of zoledronic acid 5mg one time ... $4.95 - Pharma Marketletter - ECNext

Teva Announces Tentative Approval of Risedronate Sodium Tablets.  -  Aug 12, 2005
JERUSALEM -- Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced today that the US Food and Drug Administration has granted tentative approval for ... $4.95 - Business Wire - ECNext

Osteoporosis; Reports describe recent advances in osteoporosis …  -  Feb 14, 2005
We investigated the effect of the reduction of turnover with risedronate on trabecular ... "In the risedronate group, the bone volume and the architectural ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Teva gets tentative appro for risedronate.(Teva Pharmaceutical...  -  Aug 22, 2005
Jerusalem, Israel-headquartered Teva Pharmaceutical Industries has obtained tentative clearance to market risedronate sodium, a generic version of Procter ... $4.95 - Pharma Marketletter - ECNext

In brief: Risedronate may be more effective  -  Dec 2, 2006
Risedronate may be more effective than alendronate in preventing fractures in women with osteoporosis, a large retrospective study has revealed. ... Pay-Per-View - Chemist & Druggist - Factiva, from Dow Jones

IN BRIEF: Risedronate may improve.  -  Mar 31, 2007
Risedronate may improve bone health in people who lack exercise due to Parkinson's disease, say Japanese researchers. A two-year study of 242 elderly men ... $9.94 - Chemist & Druggist - Alacra Store

IN BRIEF: Risedronate may improve.(Brief article)  -  Mar 31, 2007
Risedronate may improve bone health in people who lack exercise due to Parkinson's disease, say Japanese researchers. A two-year study of 242 elderly men ... $4.95 - Chemist & Druggist - ECNext

Good data for Novartis' Aclasta vs risedronate.(Brief article)  -  Mar 27, 2006
Swiss drug major Novartis has reported strong data on Aclasta (zoledronic acid 5mg solution for infusion), as a treatment for Paget's disease of the bone, ... $4.95 - Pharma Marketletter - ECNext

Osteoporosis; Researchers' findings advance osteoporosis research  -  Jan 27, 2005
Study 1: A recent study analyzed the cost-effectiveness of risedronate ... To determine if risedronate is cost effective for postmenopausal women with ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

Osteoporosis; Researchers' findings advance osteoporosis research  -  Jan 24, 2005
Study 1: A recent study analyzed the cost-effectiveness of risedronate ... To determine if risedronate is cost effective for postmenopausal women with ... Pay-Per-View - Biotech Business Week - Factiva, from Dow Jones

… for Once Monthly Dosing Regimen of Risedronate to Treat Postmenopau  -  Sep 19, 2007
In the non-inferiority study comparing risedronate 150 mg once monthly to ... "Risedronate is already approved to reduce the risk of both spinal and ... Pay-Per-View - PR Newswire - HighBeam Research

Osteoporosis; Researchers' findings advance osteoporosis research  -  Jan 28, 2005
Study 1: A recent study analyzed the cost-effectiveness of risedronate ... To determine if risedronate is cost effective for postmenopausal women with ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Osteoporosis treatment in 2005.(Editorial)  -  Oct 1, 2005
Safety and efficacy of risedronate in reducing fracture risk in osteoporotic women aged 80 and older: implications for the use of antiresorptive agents in ... $4.95 - Southern Medical Journal - ECNext

Call For Greater Use Of Comparative Effectiveness Studies To Help …  -  Apr 10, 2007
The RisedronatE, ALendronate (REAL) cohort study was a retrospective analysis ... The risedronate and alendronate groups were compared for risk factors for ... Medical News Today - Medical News Today (press release)

Osteoporosis; New findings in the area of osteoporosis detailed  -  Mar 22, 2005
Study 1: Data from 5 years of risedronate treatment in postmenopausal women recently ... "We have recently reported that risedronate preserves normal bone ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

macular degeneration Prism l ...  -  Aug 23, 2005
However, five women who took risedronate broke a hip, compared with 19 ... Bone mineral density increased in the risedronate group and decreased in the ... Pay-Per-View - Washington Post - ProQuest Archiver

Osteoporosis; New findings in the area of osteoporosis detailed  -  Mar 24, 2005
Study 1: Data from 5 years of risedronate treatment in postmenopausal women recently ... "We have recently reported that risedronate preserves normal bone ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

Osteoporosis; New findings in the area of osteoporosis detailed  -  Mar 26, 2005
Study 1: Data from 5 years of risedronate treatment in postmenopausal women recently ... "We have recently reported that risedronate preserves normal bone ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Higher Persistency Rates Seen With FOSAMAX(R) Once Weekly …  -  Sep 25, 2006
At greater than 360 days, persistency rates were 18.9 percent (alendronate or alendronate/cholecalciferol), 17.4 percent (risedronate or risedronate with ... Medical News Today - Medical News Today (press release)

Higher Persistency Rates Seen with FOSAMAX(R) Once Weekly …  -  Sep 19, 2006
...--At greater than 360 days, persistency rates were 18.9 percent (alendronate or alendronate/cholecalciferol), 17.4 percent (risedronate or risedronate with ... Free with registration - Business Wire - AccessMyLibrary.com

Kurashiki Medical Center, Okayama; Induced apoptosis studied, kinase ...  -  Aug 17, 2005
..."Risedronate facilitated the relocation of Ras from membrane to cytosol through ... Accordingly, risedronate suppressed the phosphorylation of ERK 1/2, ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Osteoporosis Medications - Osteoporosis Health Information - NY Times...  -  Aug 4, 2008
These pills include alendronate (Fosamax, generic), risedronate (Actonel), ... Risedronate is also available in a pill that contains calcium, ... New York Times

Apoptosis; Findings describe new data in apoptosis research  -  Nov 6, 2005
..."Risedronate facilitated the relocation of Ras from membrane to cytosol through ... Accordingly, risedronate suppressed the phosphorylation of ERK 1/2, ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Apoptosis; Findings describe new data in apoptosis research  -  Oct 31, 2005
..."Risedronate facilitated the relocation of Ras from membrane to cytosol through ... Accordingly, risedronate suppressed the phosphorylation of ERK 1/2, ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Higher Persistency Rates Seen with FOSAMAX(R) Once Weekly …  -  Sep 19, 2006
...--At greater than 360 days, persistency rates were 18.9 percent (alendronate or alendronate/cholecalciferol), 17.4 percent (risedronate or risedronate with ... $4.95 - Business Wire - ECNext

Loislaw Federal District Court Opinions - PROCTOR & GAMBLE …  -  Feb 28, 2008
Proctor & Gamble's original Complaint, filed on August 13, 2004, alleged that Teva's efforts to market a generic version West Page 479 of risedronate sodium ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

New Study Shows Actonel Almost Halves The Risk Of Hip Fractures …  -  Nov 24, 2006
..."The rapid onset of fracture reduction observed for risedronate in this study is ... The RisedronatE, ALendronate (REAL) cohort study was a retrospective ... Medical News Today - Medical News Today (press release)

Jury's out on weekly vs. monthly bisphosphonates.(Metabolic Disorders)  -  Jun 15, 2007
...or weekly (alendronate or risedronate) bisphosphonate. A total of 4335 women were identified on alendronate or risedronate and 213 on ibandronate. ... Free with registration - Family Practice News - AccessMyLibrary.com

… Study of the Effects of the Bisphosphonate Risedronate on Bone...  -  Apr 26, 2005
To determine whether the bisphosphonate risedronate and calcium are safe and ... Compared to the placebo group risedronate resulted in a 2.0% (95%CI, ... Nature.com

… Data Reports on the Safety and Efficacy of Risedronate for the...  -  Jun 5, 2006
New Phase III Data Reports on the Safety and Efficacy of Risedronate for the Treatment of Male Osteoporosis. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Brand Names/Synonyms:
Risedronate is also known by the following brand names and/or synonymsActonel; Pyridine N-Oxide; Pyridostigmine Bromide; Pyridostigmine Bromine; Risedronate; Risedronate Sodium; Risedronic Acid

Drug Category:
Risedronate is categorized under the following by the FDA: Antiresorptives; Bisphosphonates; Antihypocalcemic Agents;

Dosage Forms:
TABLET

Absorption:
Rapid absorption (~1 hr) after an oral dose, occurs throughout the upper gastrointestinal tract

Interactions:
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Chemical IUPAC Name:
(1-hydroxy-1-phosphono-2-pyridin-3-yl-ethyl)phosphonicacid





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