Salagen

This page contains recent news articles, when available, and an overview of Salagen but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Salagen
(when available)

Pharmacology and use:
Pilocarpine is a choline ester miotic and a positively charged quaternary ammonium compound. Pilocarpine, in appropriate dosage, can increase secretion by the exocrine glands. The sweat, salivary, lacrimal, gastric, pancreatic, and intestinal glands and the mucous cells of the respiratory tract may be stimulated. When applied topically to the eye as a single dose it causes miosis, spasm of accommodation, and may cause a transitory rise in intraocular pressure followed by a more persistent fall. Dose-related smooth muscle stimulation of the intestinal tract may cause increased tone, increased motility, spasm, and tenesmus. Bronchial smooth muscle tone may increase. The tone and motility of urinary tract, gallbladder, and biliary duct smooth muscle may be enhanced. Pilocarpine may have paradoxical effects on the cardiovascular system. The expected effect of a muscarinic agonist is vasodepression, but administration of pilocarpine may produce hypertension after a brief episode of hypotension. Bradycardia and tachycardia have both been reported with use of pilocarpine. For the treatment of radiation-induced dry mouth (xerostomia) and symptoms of dry mouth in patients with Sjögrens syndrome

Mechanism Of Action:
Pilocarpine is a cholinergic parasympathomimetic agent. It increase secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary muscle (when given topically to the eyes) by mainly stimulating muscarinic receptors.

News Articles on Pilocarpine

… FDA Approval for Generic Version of SALAGEN(R) Tablets; Global …  -  Apr 5, 2006
IMPAX Laboratories, Inc. (NASDAQ:IPXL) today announced that the US Food and Drug Administration (FDA) has granted approval of the Company's Abbreviated New ... Genetic Engineering News - Genetic Engineering News (press release)

Alpharma debuts authorized generic Salagen.(Brief Article)  -  Feb 28, 2005
As a result of an agreement with MGI Pharma signed in January, Alpharma has now launched pilocarpine 5mg tablets, the generic version of the former's ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Dry eyes and mouth point to Sjogren's syndrome  -  May 23, 2007
Pilocarpine (Salagen) and cevimeline (Evoxac) are pills. that promote saliva production. Your wish has been fulfilled by the Sjogren's Syndrome Foundation, ... $3.50 - The Gazette - NewsBank

… Drugs; IMPAX receives FDA approval for generic version of SALAGEN ...  -  May 3, 2006
MGI Pharma, Inc., markets SALAGEN Tablets for the treatment of symptoms of dry mouth from salivary gland hypofunction caused by radiotherapy for cancer of ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

MEDICINE CABINET: Options for treating inflamed salivary glands  -  Dec 2, 2008
..._ Medications, such as pilocarpine (Salagen), to increase salivary flow for Sjogren's syndrome. In general, it makes sense to see an otolaryngologist (ear, ... Pay-Per-View - Newsday - ProQuest Archiver

SJOGREN'S CAUSES DRY EYES, MOUTH  -  Nov 6, 2008
Evoxac and Salagen (pilocarpine) can coax saliva from the salivary glands. Artificial tears keep the eyes moist. Restasis eyedrops often can spur the ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

… Launches Authorized Generic of MGI PHARMA's Salagen(R) 5mg Tablets …  -  Feb 22, 2005
Alpharma Launches Authorized Generic of MGI PHARMA's Salagen(R) 5mg Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

First-Time Generic Approvals: Glucotrol XL, Retrovir, Salagen  -  Apr 7, 2006
April 7, 2006 -- The US Food and Drug Administration (FDA) has approved first-time generic formulations of glipizide 2.5-mg extended-release tablets for the ... Medscape

Drug Development; Generic Salagen 5mg tablets launched  -  Apr 4, 2005
2005 APR 4 - (NewsRx.com) -- Alpharma, Inc., announced that as a result of an agreement with MGI Pharma, Inc., in January 2005, the company has launched ... Pay-Per-View - Pharma Business Week - Factiva, from Dow Jones

… Drugs; IMPAX receives FDA approval for generic version of SALAGEN ...  -  May 4, 2006
MGI Pharma, Inc., markets SALAGEN Tablets for the treatment of symptoms of dry mouth from salivary gland hypofunction caused by radiotherapy for cancer of ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

… Launches Authorized Generic of MGI PHARMA's Salagen(R) 5mg Tablets …  -  Feb 22, 2005
Alpharma Inc. today announced that, as a result of an agreement with MGI PHARMA, INC. in January 2005, the company launched pilocarpine 5mg tablets, ... $4.95 - PR Newswire - ECNext

FDA OKs IMPAX' generic Salagen.(Food and Drug Administration)(Impax …  -  Apr 3, 2006
IMPAX Laboratories says that the US Food and Drug Administration has granted approval of its Abbreviated New Drug Application for a generic version of ... $4.95 - Pharma Marketletter - ECNext

… products coming.(Impax Laboratories Inc.'s Salagen gets FDA...  -  May 1, 2006
Impax Laboratories Inc.'s Salagen gets FDA approval)(Perrigo Co.'s terconazole drugs gets FDA approval)(Mylan Laboratories Inc.'s antihistamine gets FDA ... Pay-Per-View - Chain Drug Review - HighBeam Research

Liberan en la Cañada Real a una menor secuestrada en Manchester  -  Sep 22, 2007
Sin embargo, el padre, Salagen S., que lleva años asentado en el Reino Unido, ... A finales del pasado mes de agosto, Salagen tuvo que ausentarse de ... ABC.es

IMPAX GETS FDA APPROVAL FOR GENERIC VERSION OF SALAGEN  -  Apr 12, 2006
Impax Laboratories has announced that the FDA has granted approval of the company's abbreviated new drug application (ANDA) for a generic version of Salagen ... Pay-Per-View - FDAnews Drug Pipeline Alert - Factiva, from Dow Jones

Press Release: European Approval for Roche's New Invirase 500 mg …  -  May 27, 2005
Administration approved the Salagen 7.5 mg tablet as an alternative strength to the currently marketed Salagen 5 mg tablet. Salagen tablets are indicated ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Loislaw Federal District Court Opinions - HARKINS v. BARNHART (D.Kan …  -  Mar 11, 2005
Id. Plaintiff testified that as of the date of the hearing, she was taking the following medications: Neurontin, Vioxx, Salagen, Altace, methotrexate, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Tiara Sánchez Vargas  -  Feb 23, 2007
...“Tenemos este medicamento (Salagen), que bien puede ser usado por algún enfermo, el problema es que hasta ahora no hay nadie que lo necesite�, ... La Prensa - La Prensa (Nicaragua) (Suscripción)

Company Profile Report  -  Jan 26, 2008
Products:. Salagen (Pilocarpine Hydrochloride). Phase I/Phase II Clinical Stage Products ... Salagen (Pilocarpine Hydrochloride). Hematology ... $50.00 - Revere Reports - Revere

FDA first-time generics approvals--2006.(Special Report)(Statistical...  -  Feb 19, 2007
Salagen--complements the 5-mg pilocarpine hydrochloride tablets ... Administration approval to market meloxicam tablets in the U.S. Meloxicam is ... tablets ... Pay-Per-View - Chain Drug Review - HighBeam Research

Actavis launches pilocarpine 7.5mg in USA.(launch of pilocarpine...  -  Sep 11, 2006
Pilocarpine 7.5mg is the authorized generic of MGI Pharma's Salagen 7.5mg ... Brand sales of Salagen 7.5mg in the USA were around $2.2 million for the 12 ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Press Release: Actavis Launches Pilocarpine Tablets 7.5mg in the US -...  -  Sep 6, 2006
Pilocarpine Tablets 7.5mg is the authorized generic of MGI Pharma's Salagen(R) 7.5mg tablets, ... Read all of this article with a FREE trial ... Pay-Per-View - PR Newswire - HighBeam Research

THURSDAY'S RESULTS  -  Mar 3, 2006
Salagen 8-4; Greer (S) d. Medina 8-4; Doubles -- Wright/Pino (SB) d. ... Addison/Salagen 8-4. Records -- Stranahan 1- 3. Flanagan 6, McArthur 1 ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

Detenidos en Madrid cuatro rumanos que secuestraron a dos chicas en …  -  Sep 21, 2007
El pasado mes de agosto, Salagen S., miembro de la comunidad gitana rumana de Manchester, viajó a su país al objeto de asistir al funeral de un familiar. ... elmundo.es

惱人的乾燥症好發於中年婦女  -  May 18, 2008
...最近衛生署也核�一種腺體刺激藥物(Salagen),它是一種Pilocarpin類的藥物,惟使用 此藥並��個病人都��得�見的療效,端視病患唾液腺有無明顯纖維化�相關藥物 ... 自由時報

Effect of pilocarpine hydrochloride on unstimulated whole saliva flow...  -  Feb 19, 2007
The case group was orally administered 5 mg of pilocarpine (Salagen, Novartis, UK), four times per day (20 mg/day) for 7 days. The control group received an ... Nature.com

RESOURCES  -  Feb 20, 2005
For serious saliva shortage, take medications that stimulate the salivary glands, such as pilocarpine (Salagen) or cevimeline (Evoxac). ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

A controlled release pilocarpine buccal insert in the treatment of...  -  Feb 2, 2007
In recent years the muscarinic agonist pilocarpine (Salagen ® , Novartis) has been used to some effect. 7 It was launched in the UK in 1995, originally only ... Nature.com

The wicked wolf of Wall Street  -  Jan 15, 2008
...two heaped tablespoons of Senokot (constipation); 20 milligrams of Salagen (dry mouth); and a pint of Macallan scotch whisky to wash it all down. ... Daily Mail

SMALL BUSINESS; The simple water can gets an update; Ovation …  -  Jul 2, 2007
Later this year the company expects to apply for FDA approval to market Salagen as a treatment for Sjogren's Syndrome, which describes the dry mouth and ... Pay-Per-View - Star Tribune - HighBeam Research

Eisai Gaining Cancer Portfolio In $3.9B MGI Acquisition  -  Dec 11, 2007
...for ovarian cancer; and Salagen (pilocarpine hydrochloride), for dry mouth associated with Sjogren's Syndrome and radiation therapy. ... BioWorld Online - BioWorld Online

Dry mouth, eyes often traced to Sjogren's syndrome  -  Mar 28, 2005
Evoxac and Salagen are two medicines that can stimulate saliva production even in salivary glands affected by Sjogren's. Artificial tears provide a liquid ... $3.50 - The Gazette - NewsBank

Article: Erbitux receives federal approval as first new head and neck...  -  Mar 1, 2006
Article: MGI PHARMA's SALAGEN(R) TABLETS CLEARED FOR MARKETING BY FDA; ... PR Newswire; March 22, 1994 ; 700+ words ... ... xerostomia) in head and neck ... Pay-Per-View - AP Worldstream - HighBeam Research

Kissei Announces New Drug Application for Silodosin has been Filed...  -  Feb 13, 2008
Glufast(R), a rapid onset and short-acting insulin secretagogue, was launched in 2004; Salagen(R), a therapeutic agent for dry mouth induced by radiation ... japancorp.net

NJ BRIEFS | Article from The Record (Bergen County, NJ) | HighBeam …  -  Feb 23, 2005
Separately Tuesday, Alpharma said it launched an authorized generic version of Salagen, which cancer patients use for treating dry mouth caused by radiation ... Pay-Per-View - The Record - HighBeam Research

MEDICINES RELIEVE DRYNESS  -  Jan 26, 2007
Salagen and Evoxac are two oral medicines that increase saliva production. Contact the Sjgren's Syndrome Foundation at 800-475-6473 or on the Internet at ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

BOSTON SCI-GUIDANT DEAL GETS FTC STAFF'S CONSENT  -  Apr 6, 2006
The United States Food and Drug Administration has approved a generic equivalent of Bloomington-based MGI Pharma's Salagen tablets, which are designed to ... $2.95 - St. Paul Pioneer Press - NewsBank

Yeast Infection Medication Can WORSEN Your Medical Condition  -  Jun 27, 2008
Such medications include cevimeline (Evoxac, Daiichi) and pilocarpine (Salagen, MGI Pharma). 1. Their effect is temporary. ... California Chronicle

Sjogren's Syndrome: Causes, Symptoms, Tests, and Treatment  -  Oct 1, 2006
Two prescription medications, Salagen and Evoxac, stimulate saliva production and may relieve the dry mouth symptoms. In some patients, the anti-rheumatic ... WebMD

Approvable Letter Received from the FDA for Dacogen(TM) (Decitabine) ...  -  Sep 1, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, KADIAN(R) (sustained release morphine capsules), Salagen(R) Tablets (pilocarpine ... businesswire.com

Madrid: Patru români, arestaÅ£i pentru răpirea a două surori din …  -  Sep 21, 2007
În luna august a acestui an, Salagen S., român de etnie rromă stabilit în Manchester, a aflat de la fratele său, în timp ce se afla în România la o ... Mediafax

Article: Treatment pearls for common breast cancer-related symptoms.(...  -  Mar 15, 2008
Pilocarpine (Salagen) shows enough promise that Dr. Loprinzi and colleagues have ... Read all of this article with a FREE trial ... Pay-Per-View - Family Practice News - HighBeam Research

Dry mouth parches folks of all ages  -  Jun 28, 2005
Salagen and Evoxac are prescribed for Sjogren's syndrome because they stimulate the salivary glands and the tear ducts. Cyclosporin A, a drug taken orally ... sptimes.com

Saliva shortage - Seven tips for a dry mouth  -  Aug 31, 2006
Pilocarpine (Salagen) is used more often, but cevimeline (Evoxac) seems to have fewer side effects. 7. Get special treatments for your teeth and gums. ... $2.95 - Fort Worth Star-Telegram - NewsBank

Article: Drug promising for vaginal dryness after breast cancer.(Acros...  -  Mar 1, 2008
Indeed, pilocarpine (Salagen) has shown enough promise that Dr. Loprinzi and his colleagues have embarked on an ongoing randomized, double-blind, ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Don't count your eggs before they're hatched  -  Jul 15, 2007
MOGN has had excellent successes with Glidel Wafers for glioblastomas, with Hexaline capsules for ovarian cancer, Salagen for treatment of radiation-induced ... NewsOK.com

MGI PHARMA to Present at the 23rd Annual JPMorgan Healthcare …  -  Jan 6, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... Free with registration - Business Wire - AccessMyLibrary.com

Merger and Acquisition Scenario  -  Jan 26, 2008
Salagen (Pilocarpine Hydrochloride); Dacogen (Decitabine); Gliadel Wafer (Polifeprosan 20 With Carmustine Implant); Irofulven (Hydroxymethylacylfulvene) ... $250.00 - Revere Reports - Revere

Press Release: N30 Pharma Announces Successful Initiation of Human …  -  Jan 28, 2008
Salagen is a drug that MGI Pharma has studied as a treatment ... of laboratory, animal and human studies before it can be submitted . ... Pay-Per-View - PR Newswire - HighBeam Research

MGI PHARMA Analyst and Institutional Investor Event to Be Webcast on ...  -  May 25, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... businesswire.com

Japan stock market week to May 28, 2007.(Financial report)  -  Jun 4, 2007
Sales of Salagen (pilocarpine), for the treatment of dry mouth, first marketed in September 2005, grew to 132.0 million yen from 58.0 million yen a year ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Press Release: BHIP, CADX, MOGN, WEESF, TFZP Have Also Been …  -  Jan 24, 2008
Gliadel Wafer for the treatment of malignant glioma, and recurrent glioblastoma multiforme; Salagen Tablets, a treatment for the symptoms of xerostomia ... Pay-Per-View - M2 Presswire - HighBeam Research

Lannett Company Receives Approval for Pilocarpine HCL  -  Oct 17, 2005
Pilocarpine HCl is the generic version of Salagen(R), marketed by MGI Pharma. Lannett Company, founded in 1942, develops, manufactures, packages, ... RedOrbit

Mouth Sores (Mucositis)  -  May 25, 2007
...mouthwashes; cryotherapy (sucking on ice chips) to minimize the damage from chemotherapy drugs; Salagen®, a drug that stimulates salivary flow; ... Cancer Consultants

Merger and Acquisition Scenario  -  Jan 26, 2008
Salagen (Pilocarpine Hydrochloride); Dacogen (Decitabine); Gliadel Wafer (Polifeprosan 20 With Carmustine Implant); Irofulven (Hydroxymethylacylfulvene) ... $250.00 - Revere Reports - Revere

MGI PHARMA Fourth Quarter and Year End 2004 Financial Results; …  -  Feb 9, 2005
MGI PHARMA markets Aloxi(TM) (palonosetron hydrochloride) injection, Salagen(R) Tablets (pilocarpine hydrochloride), and Hexalen(R) (altretamine) capsules ... businesswire.com

Oral Agreement  -  May 25, 2006
When IMRT is not suitable for the patient, the radiation oncologist can prescribe medication, such as Salagen, to stimulate the flow of saliva from fully to ... Dental Economics

YOUR HEALTH | www.kilgorenewsherald.com | Kilgore News  -  May 30, 2007
Pilocarpine (Salagen) and cevimeline (Evoxac) are pills that promote saliva production. Your wish has been fulfilled by the Sjogren's Syndrome Foundation, ... Kilgore News Herald

MGI, SuperGen Get Dacogen Approvable Letter, Have Hope  -  Sep 6, 2005
MGI's portfolio includes four marketed products: Aloxi (palonosetron hydrochloride) injection, Kadian (sustained-release morphine capsules), Salagen tablets ... BioWorld Online - BioWorld Online

MGI PHARMA to Present at the 23rd Annual JPMorgan Healthcare …  -  Jan 13, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... businesswire.com

Q2 2006 MGI Pharma Earnings Conference Call - Part 3.  -  Jul 19, 2006
You also have Hexalen, Salagen. We didn't refer because of the relative size of those revenues and I guess the lack of focus. ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

MGI PHARMA Reports Fourth Quarter and Fiscal 2004 Results  -  Dec 31, 2005
During the fourth quarter of 2004, US sales of Aloxi injection totaled $56.0 million and sales of Salagen(R) Tablets (pilocarpine hydrochloride) were $7.8 ... businesswire.com

Contact wearers benefit from expanding dry eye therapy: management …  -  May 15, 2005
Oral secretogogue therapy using the cholinergic agonists pilocarpine (Salagen, MGI PHARMA Inc.) or cevimeline (Evoxac, Daiichi Pharmaceuticals) to increase ... Free with registration - Ophthalmology Times - AccessMyLibrary.com

Chronic epiphora.(Signs and Symptoms)(Disease/Disorder overview)  -  Mar 15, 2006
This may be achieved by using artificial tear preparations, immunomodulatory agents (e.g., Restasis), or oral secretagogues (e.g., Salagen, Evoxac). ... Free with registration - Review of Optometry - AccessMyLibrary.com

New generics.(drug approvals, product introduction)(Brief Article)  -  Mar 21, 2005
The product is a generic version of MGI Pharma's Salagen 5-mg tablets. The medication is indicated for the treatment of dry mouth from salivary gland ... Free with registration - Drug Topics - AccessMyLibrary.com

MGI PHARMA Fourth Quarter and Year End 2004 Financial Results; …  -  Feb 2, 2005
MGI PHARMA markets Aloxi(TM) (palonosetron hydrochloride) injection, Salagen(R) Tablets (pilocarpine hydrochloride), and Hexalen(R) (altretamine) capsules ... Free with registration - Business Wire - AccessMyLibrary.com

Actavis Group.(RX/GENERIC DRUGS--Profiles)  -  Sep 25, 2006
The drug--the generic equivalent of MGI Pharma Inc.'s Salagen--complements the 5-mg pilocarpine hydrochloride tablets that Actavis already offers. ... Free with registration - Chain Drug Review - AccessMyLibrary.com

MGI PHARMA First Quarter 2005 Financial Results Conference Call to Be...  -  Apr 13, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate capsules), Salagen(R) Tablets (pilocarpine ... businesswire.com

Article: Medicines Co. gets FDA OK for injectable BP treatment.(RXs) ...  -  Aug 18, 2008
...version of Salagen (pilocarpine hydrochlorine) 5- and 7.5-mg tablets. MGI Pharma Inc. makes the brand name product for the treatment of symptoms of ... Pay-Per-View - Chain Drug Review - HighBeam Research

Dacogen NDA Accepted for Filing by FDA.  -  Jan 3, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

MGI PHARMA Reports Fourth Quarter and Fiscal 2004 Results.  -  Feb 9, 2005
During the fourth quarter of 2004, US sales of Aloxi injection totaled $56.0 million and sales of Salagen(R) Tablets (pilocarpine hydrochloride) were $7.8 ... $4.95 - Business Wire - ECNext

MGI PHARMA to Present at the Piper Jaffray Health Care Conference.  -  Jan 19, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

Merger and Acquisition Scenario  -  Jan 26, 2008
Salagen (Pilocarpine Hydrochloride); Dacogen (Decitabine); Gliadel Wafer (Polifeprosan 20 With Carmustine Implant); Irofulven (Hydroxymethylacylfulvene) ... $250.00 - Revere Reports - Revere

MGI PHARMA to Present at the Merrill Lynch Global Pharmaceutical, …  -  Feb 3, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

MGI PHARMA to Present at the Pacific Growth Equities Life Sciences …  -  Jun 1, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

Finance; Oncology-focused biopharmaceutical company reports 4Q,...  -  Mar 11, 2005
During the fourth quarter of 2004, US sales of Aloxi injection totaled $56.0 million and sales of Salagen Tablets (pilocarpine hydrochloride) were $7.8 ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

MGI PHARMA To Present at the Banc of America Securities 2005 …  -  Jul 22, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

MGI PHARMA to Present at the 2005 Banc of America Securities Health …  -  May 10, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate capsules), Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

MGI PHARMA to Present at the Bear Stearns 18th Annual Healthcare …  -  Sep 5, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

MGI PHARMA to Present at the Leerink Swann & Company/MEDACorp …  -  Feb 22, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

MGI PHARMA to Present at the BioCentury NewsMakers in the Biotech …  -  Sep 2, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

James Hawley Joins MGI PHARMA As Senior Vice President; To Be …  -  Jan 31, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate capsules), Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

Say no to these drug issues  -  May 10, 2006
Hexalin (which treats refractory ovarian cancer) and Salagen tablets (which treat dry mouth resulting from neck and head cancer radiation). ... $2.95 - Herald News - NewsBank

SuperGen may or may not be a super investment  -  Jul 11, 2007
MOGN has had excellent successes with Glidel Wafers for glioblastomas, with Hexaline capsules for ovarian cancer, Salagen for treatment of radiation-induced ... $2.95 - Courier News - NewsBank

MGI PHARMA Second Quarter 2005 Financial Results Conference Call to …  -  Jul 6, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

Press Release: SEDONA Announces Second Quarter 2006 Operating …  -  Aug 14, 2006
Lastly, new data supporting the effectiveness of Salagen Tablets was presented at the annual meeting of the European Society of Therapeutic Radiation ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  May 5, 2007
Salagen (Pilocarpine Hydrochloride); Dacogen (Decitabine); Gliadel Wafer (Polifeprosan 20 With Carmustine Implant); ZYC300 (DNA Based Immunostimulant) ... $250.00 - Revere Reports - Revere

Saliva shortage: Seven tips for a dry mouth.  -  Feb 1, 2005
Pilocarpine (Salagen) is used more often, but cevimeline (Evoxac) seems to have fewer side effects. Get special treatments for your teeth and gums. ... Pay-Per-View - Harvard Health Letter - Factiva, from Dow Jones

POTPOURRI; Keeping mouth moist plays key role in oral hygiene |...  -  Mar 3, 2005
...for more serious cases of dry mouth, they include pilocarpine (Salagen) which is used more often, although cevimeline (Evoxac) seems to have fewer ... Pay-Per-View - Filipino Reporter - HighBeam Research

Generics makers keep product pipeline moving.  -  Sep 25, 2006
Pilocarpine tablets, 7.5 mg, are the authorized generic equivalent of MGI Pharma's Salagen. The branded drug had sales in the United States of some $2.2 ... $20.00 - Chain Drug Review - Alacra Store

FTC clears Eisai takeover of MGI Pharma.(News)(United States. Federal...  -  Feb 4, 2008
Remeron SolTab mirtazapine Organon Prasco Salagen pilocarpine MGI Pharma Alpharma (Purepac) Tambocor Flecainide 3M Mylan Terazol3 ... ... Pay-Per-View - Chain Drug Review - HighBeam Research

Bucks medication monitor gets 'genius grant'  -  Sep 24, 2005
Around the same time, a cancer patient was mistakenly given Salagen, a drug for Parkinson's disease, and experienced an uncontrollable movement that is a ... $3.50 - Bucks County Courier Times - NewsBank

Two drug issues are bitter pills  -  May 9, 2006
Giladel Water (a chemotherapy agent that treats high-grade malignant gliomas), Hexalin (refractory ovarian cancer) and Salagen Tablets (to treat dry ... $2.95 - News Sun - NewsBank

Merger and Acquisition Scenario  -  Jan 26, 2008
Salagen (Pilocarpine Hydrochloride); Dacogen (Decitabine); Gliadel Wafer (Polifeprosan 20 With Carmustine Implant); Irofulven (Hydroxymethylacylfulvene) ... $250.00 - Revere Reports - Revere

MGI PHARMA Analyst and Institutional Investor Event to Be Webcast on ...  -  May 18, 2005
MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection, Kadian(R) (sustained release morphine sulfate) capsules, Salagen(R) Tablets (pilocarpine ... $4.95 - Business Wire - ECNext

Merger and Acquisition Scenario  -  Nov 24, 2007
Salagen (Pilocarpine Hydrochloride); Dacogen (Decitabine); Gliadel Wafer (Polifeprosan 20 With Carmustine Implant); Irofulven (Hydroxymethylacylfulvene) ... $250.00 - Revere Reports - Revere

Breast ca-related symptoms are hard to treat: vaginal dryness,...  -  Apr 1, 2008
Pilocarpine (Salagen) shows enough promise in improving vaginal dryness that Dr. Loprinzi and colleagues have embarked on an ongoing randomized, ... Pay-Per-View - Internal Medicine News - HighBeam Research

Medical Mailbag: Try sugar-free candy and drink plenty of water for a...  -  Nov 13, 2007
Prescription medication, such as Salagen, can increase saliva production. Ganglion cyst Dear Dr. Malloy: What is a ganglion cyst and what are the treatment ... $2.95 - Daily Southtown - NewsBank

Lifestyle modifications can reduce dental decay in Sjogren's.( …  -  Apr 1, 2005
Two prescription salivary substitute medications--pilocarpine (Salagen) and cevimeline (Evoxac)--can be an effective adjunct to lifestyle modifications, ... Pay-Per-View - Internal Medicine News - HighBeam Research

Act locally and use behavioral approach for vaginal dryness. |...  -  Sep 15, 2005
Pilocarpine (Salagen) shows enough promise in improving vaginal dryness that Dr. Loprinzi and colleagues ... Internal Medicine News ... Pay-Per-View - Internal Medicine News - HighBeam Research

Brand Names/Synonyms:
Salagen is also known by the following brand names and/or synonymsAdsorbocarpine; Akarpine; Almocarpine; Ami-Pilo; Amistura P; Beta-Pilocarpine Hydrochloride; Epicar; HSDB 3163; Isopto Carpine; Isoptocarpine; Mi-Pilo; Mi-Pilo Ophth Sol; Minims Pilocarpine; Miocarpine; Mistura P; NSC5746; Ocu-Carpine; Ocusert P 20; Ocusert Pilo; Ocusert Pilo-20; Ocusert Pilo-40; P.V. Carpine Liquifilm; Pilagan; Pilocar; Pilocar Smp; Pilocarpal; Pilocarpin; Pilocarpine; Pilocarpine Chloride; Pilocarpine Hcl; Pilocarpine Hydrochloride; Pilocarpine Monohydrochloride; Pilocarpine Muriate; Pilocarpine [Usan:Ban:Jan]; Pilocarpine, Hydrochloride; Pilocarpine, Monohydrochloride; Pilocarpine-; Pilocarpol; Pilocel; Pilokarpin; Pilokarpin Monohydrochloride; Pilokarpol; Pilomiotin; Pilopine Hs; Piloptic-&Frac12;; Piloptic-1; Piloptic-2; Piloptic-3; Piloptic-4; Piloptic-6; Piloptic-½; Pilostat; Pilovisc; Salagen; Sno Pilo; Spersacarpine; Spersacarpine Hydrochloride; Syncarpine

Drug Category:
Salagen is categorized under the following by the FDA: Cholinergic Agents; Muscarinic Agonists; Miotics; ATC:N07AX01; ATC:S01EB01

Dosage Forms:
DROPS; GEL; IMPLANT; LIQUID; SOLUTION

Absorption:
There was a decrease in the rate of absorption of pilocarpine from SALAGEN Tablets when taken with a high fat meal by 12 healthy male volunteers

Interactions:
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Chemical IUPAC Name:
3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one





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