Septocaine

This page contains recent news articles, when available, and an overview of Septocaine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Septocaine
(when available)

Pharmacology and use:
Epinephrine is indicated for intravenous injection in treatment of acute hypersensitivity, treatment of acute asthmatic attacks to relieve bronchospasm, and treatment and prophylaxis of cardiac arrest and attacks of transitory atrioventricular heart block with syncopal seizures (Stokes-Adams Syndrome). The actions of epinephrine resemble the effects of stimulation of adrenergic nerves. To a variable degree it acts on both alpha and beta receptor sites of sympathetic effector cells. Its most prominent actions are on the beta receptors of the heart, vascular and other smooth muscle. When given by rapid intravenous injection, it produces a rapid rise in blood pressure, mainly systolic, by (1) direct stimulation of cardiac muscle which increases the strength of ventricular contraction, (2) increasing the heart rate and (3) constriction of the arterioles in the skin, mucosa and splanchnic areas of the circulation. When given by slow intravenous injection, epinephrine usually produces only a moderate rise in systolic and a fall in diastolic pressure. Although some increase in pulse pressure occurs, there is usually no great elevation in mean blood pressure. Accordingly, the compensatory reflex mechanisms that come into play with a pronounced increase in blood pressure do not antagonize the direct cardiac actions of epinephrine as much as with catecholamines that have a predominant action on alpha receptors. For the treatment of Anaphylatic reactions

Mechanism Of Action:
Epinephrine works via the stimulation of alpha and beta-1 adrenergic receptors, and a moderate activity at beta-2 adrenergic receptors.

News Articles on Epinephrine

Local anesthesia a key consideration  -  Jun 25, 2007
The simple fact that there is so much controversy about Septocaine has resulted in ... I am not hesitant to use Septocaine for blocks when it's indicated, ... Dental Economics

Olson v. Septodont, Inc., No. C07-5355 RBL (WDWash. 09/20/2007)  -  Sep 20, 2007
Dr. Bird administered a new dental anesthetic, Septocaine, in order to replace ... Septodont, a Delaware corporation, manufactures Septocaine, and Burkhart, ... $2.95 - U.S. District Court, Western District... - VersusLaw

Cementation: To numb or not to numb?  -  May 3, 2006
Septocaine does just that. The absorption of Septocaine is so high that - in ... Then, when necessary, Septocaine is an excellent local anesthetic with high ... Dental Economics

Local issues with local anaesthetic.(mouthpiece)  -  May 1, 2007
The two main commercial preparations are Septocaine from Septodont and Ubistesin from ... Septocaine is regarded as a 'special' that I can source from Irish ... Free with registration - Dental Products Report Europe - AccessMyLibrary.com

New Products  -  Dec 22, 2006
Septodont's new Septocaine® with epinephrine 1:200000 (Articaine hydrochloride 4% with Epinephrine 1:200000 injection) is indicated for local, infiltrative, ... Dental Economics

Washington Administrative Code - WAC 260-70-680 This section …  -  Mar 17, 2006
Amitril, Endep Amobarbital Amytal Amoxapine Asendin Amperozide Anilopam Anisine Aprobarbital Alurate Articaine Septocaine; Ultracaine, etc. ... Pay-Per-View - Washington Administrative Code - Loislaw

This dentist is pulling for the poor, uninsured ; Retired army dental...  -  Dec 12, 2005
He's old-fashioned: He makes his patient comfortable with a shot of Septocaine, a local anesthetic, picks up his forceps and gives a tug. ... Pay-Per-View - The Sun - ProQuest Archiver

QUESTION & ANSWER - ANSWERS TO READERS' SCIENCE-RELATED …  -  May 19, 2005
...the fatty layers of nerve membranes and to remain in solution outside the nerve. Newer drugs include prilocaine (Citanest) and articaine (Septocaine). $2.95 - Lexington Herald Leader - NewsBank

Franklin v. United States Steel Corp., No. 2:04 cv 246 (NDInd....  -  Apr 7, 2006
Franklin had been prescribed amoxicillin and hydrocone, which he had stopped taking two weeks prior to the June test, and septocaine had been used as a ... $2.95 - U.S. District Court, Northern District... - VersusLaw

Septodont, NDC sign warehouse distribution agreement  -  Jul 8, 2008
The new program expands the current offering of the image restorative line and the infection control products to include the popular Septocaine brand and ... Dental Office Magazines

Ovate pontic receptor sites  -  May 23, 2005
After use of a strong topical (Profound, 800-352-3784) and a rapidly absorbed local anesthetic (Septocaine), the teeth are prepared or the existing bridge ... Dental Economics

10 steps to efficient endo in the general practice  -  Mar 29, 2007
...to achieve initial soft tissue anesthesia, followed by one to two carpules of articaine (Septocaine) to provide great deadening in almost all cases. ... Dental Economics

Upper face treatments blossom.(Face)  -  Oct 1, 2005
I've learned a great deal from the cosmetic dentists in my area, so I will use Septocaine (lidocaine, epinephrine hydrochloride, Septodont). ... Free with registration - Cosmetic Surgery Times - AccessMyLibrary.com

Protemp™ Crown Temporization Material from 3M ESPE  -  Feb 19, 2007
Standard and Petite Aspirating Syringes from Septodont - From the people who bring you that great anesthetic, Septocaine®, comes two new syringes. ... Dental Economics

Care with comfort: an exclusive DPR survey asked about the types of …  -  Oct 1, 2006
Over the past five years since its US introduction, articaine (brand name Septocaine) has become the most used dental anesthetic brand in the US, ... Free with registration - Dental Products Report - AccessMyLibrary.com

Company announces materials division  -  Oct 9, 2007
NEW CASTLE, Delaware--Septodont, Inc., manufacturers of Septocaine and other well-known pain control products, has announced the creation of a new materials ... RDH

Xylocain Dental adrenalin «Dentsply»: Bivirkninger som følge av mulig...  -  Oct 20, 2007
Andre alternative preparater er Carbocain Dental «Dentsply», Citanest Octapressin «Dentsply», samt Septocaine «Septodont». ... Statens legemiddelverk

Brand Names/Synonyms:
Septocaine is also known by the following brand names and/or synonymsADROP; Adnephrine; Adrenal; Adrenalin; Adrenalin Chloride; Adrenalin in Oil; Adrenalin-Medihaler; Adrenalina [Dcit]; Adrenaline; Adrenaline/Epinephrine; Adrenalinum; Adrenamine; Adrenan; Adrenapax; Adrenasol; Adrenatrate; Adrenine; Adrenodis; Adrenohorma; Adrenor; Adrenosan; Adrenutol; Adrin; Adrine; Aktamin; Alphacaine Hcl W/ Epinephrine; Ana-Guard; Antiasthmatique; Arterenol; Asmatane Mist; Asthma Meter Mist; Asthma-Nefrin; Asthmahaler Mist; Asthmanefrin; Astmahalin; Astminhal; Balmadren; Bernarenin; Biorenine; Bosmin; Brevirenin; Bronkaid; Bronkaid Mist; Bronkaid Suspension Mist; Bupivacaine Hcl and Epinephrine; CCRIS 4812; Chelafrin; Citanest Forte; Corisol; D-Adrenaline; D-Epifrin; D-Epinephrine; Drenamist; Duranest; Dylephrin; Dyspne-Inhal; Epi E Z Pen Jr; Epifrin; Epiglaufrin; Epinefrin; Epinefrin [Czech]; Epinefrina; Epinefrina [Inn-Spanish]; Epinephran; Epinephrine; Epinephrine Bitartrate; Epinephrine [Usan:Inn:Jan]; Epinephrinum [Inn-Latin]; Epipen; Epipen Auto-Injector; Epipen E Z Pen; Epipen Jr.; Epipen Jr. Auto-Injector; Epirenamine; Epirenan; Epirenin; Epitrate; Eppy; Esphygmogenina; Exadrin; Glaucon; Glaucosan; Glauposine; Glycirenan; HSDB 4289; Haemostasin; Haemostatin; Hektalin; Hemisine; Hemostasin; Hemostatin; Hypernephrin; Hyporenin; IOP; Intranefrin; Iontocaine; Isoptoepinal; Kidoline; L-Adrenalin; L-Adrenaline; L-Adrenaline Base; L-Adrenaline Gr; L-Arterenol; L-Epinephine; L-Epinephrine; L-Epirenamine; L-Methylaminoethanolcatechol; L-Noradrenaline; L-Norepinephrine; Levarterenol; Levo-Methylaminoethanolcatechol; Levoarterenol; Levoepinephrine; Levonor; Levonoradrenaline; Levonorepinephrine; Levophed; Levorenen; Levorenin; Levorenine; Lidocaine Hcl W/ Epinephrine; Lidocaine Hcl and Epinephrine; Lidocaton; Lyophrin; Medihaler-Epi; Metanephrin; Methylaminoethanolcatechol; Methylarterenol; Micronefrin; Mucidrina; Myosthenine; Mytrate; Nephridine; Nephron; Nieraline; Nor-Epirenan; Noradrenalin; Noradrenaline; Norartrinal; Norepinephrine; Norepinephrine Bitartrate; Norepirenamine; Octocaine; Paranephrin; Primatene Mist; Procaine Hcl W/ Epinephrine; Rcra Waste No. P042; Rcra Waste Number P042; Renagladin; Renaglandin; Renaglandulin; Renaleptine; Renalina; Renoform; Renostypricin; Renostypticin; Renostyptin; S-2; Scurenaline; Septocaine; Simplene; Sindrenina; Soladren; Sphygmogenin; Stryptirenal; Styptirenal; Supracapsulin; Supradin; Supranefran; Supranephrane; Supranephrine; Supranol; Suprarenaline; Suprarenin; Suprel; Surenine; Surrenine; Sus-Phrine; Susphrine; Sympathin E; Sympathin I; Takamina; Takamine; Tokamina; Tolansin; Tolax; Tolcil; Tolhart; Tonogen; Twinject; Twinject 0.30; Vaponefrin; Vasoconstrictine; Vasoconstrictor; Vasodrine; Vasoton; Vasotonin; Xylocaine W/ Epinephrine

Drug Category:
Septocaine is categorized under the following by the FDA: Vasoconstrictor Agents; Mydriatics; Bronchodilator Agents; Sympathomimetic; ATC:A01AD01; ATC:B02BC09; ATC:C01CA03; ATC:C01CA24; ATC:R01AA14; ATC:R03AA01; ATC:S01EA01

Dosage Forms:
CORD; DROPS; LIQUID; METERED-DOSE (AEROSOL); PAD; PELLET; PELLET (DENTAL); SOLUTION; SPRAY

Absorption:
Usually this vasodilator effect of the drug on the circulation predominates so that the modest rise in systolic pressure which follows slow injection or absorption is mainly the result of direct cardiac stimulation and increase in cardiac output.

Interactions:
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Chemical IUPAC Name:
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol





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