Sertraline

This page contains recent news articles, when available, and an overview of Sertraline but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Sertraline
(when available)

Pharmacology and use:
Sertraline, an antidepressant drug similar to citalopram, fluoxetine, and paroxetine, is of the selective serotonin reuptake inhibitor (SSRI) type. Sertraline has one active metabolite and is used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, and post-traumatic stress disorder. For the treatment of posttraumatic stress disorder, depression, obsessive-compulsive disorder and panic disorder

Mechanism Of Action:
It is believed that sertraline inhibits reuptake of serotonin at the neuronal membrane. SSRIs have less sedative, anticholinergic, and cardiovascular effects than the tricyclic antidepressant drugs because of decreased binding to histamine, acetylcholine, and norepinephrine receptors.

News Articles on Sertraline

Antidepressants: Best for Severe Depression?  -  05 Jan 2010
Other popular SSRIS include citalopram (Celexa), fluoxetine (Prozac), and sertraline (Zoloft). Tofranil is an older medication, known as a tricyclic ... WebMD

Cognitive-Behavioral Therapy for Childhood Anxiety and Depression  -  ‎Dec 29, 2009‎
1 Patients were randomized to receive sertraline, CBT, sertraline and CBT, or placebo for 12 weeks. Combination treatment was significantly superior to ... Psychiatric Times

Fox Worked, Resided In Warren County  -  ‎Dec 16, 2009‎
The search also yielded an open prescription bottle of 10 tablets of Sertraline in the name of Michael Fox. The drug is also known as Zoloft. ... North Country Gazette

Treating depression helps with blood sugar control  -  ‎Dec 16, 2009‎
Ultimately, the study included 89 patients; 45 were randomly assigned to receive the antidepressant medication sertraline (sold as Zoloft) and 44 to a ... National Post

Comment on "Antidepressant Use and Risk of Incident Cardiovascular Morbidity ...  -  ‎Dec 14, 2009‎
Glassman AH, O'Connor CM, Califf RM; et al, Sertraline Antidepressant Heart Attack Randomized Trial (SADHEART) Group. Sertraline treatment of major ... Archives of Internal Medicine

Is there hope for life with depression?  -  ‎Dec 22, 2009‎
Will I always be on these meds (I take 200 mg sertraline and 300 mg bupropion)? What about starting a family? That's nine-plus months without them and after ... CNN

Medical marijuana attorney Rob Corry: "The future is here"  -  ‎Dec 18, 2009‎
These medications include Copaxone, Gabapentin, Cyclobenzaprine, Meloxicam, Sertraline, Advair, and Mirapex. With the addition of medical marijuana to her ... Westword (blog)

Prescription Drug Coupons Offer Best Savings on Prescription Drugs  -  ‎Dec 30, 2009‎
Drug coupons are available for discounts on Phentermine, Viagra, Adderal, Sertraline, Adipex, Alprazolam, Lorazepam, Tramadol, Paroxepine, Yasmin, ... PR Newswire (press release)

What Is St. John's Wort? How Effective Is St. John's Wort?  -  ‎Dec 31, 2009‎
Although studies comparing St. John's wort against SSRIs (selective serotonin reuptake inhibitor), such as Prozac (fluoxetine) or Zoloft (sertraline) have ... Medical News Today

St. John's wort - The Cataract Connection  -  ‎Dec 10, 2009‎
...imipramine [Tofranil]; and sertraline [Zoloft], in the treatment of mild to moderate depression with far fewer side effects of standard antidepressants. ... InjuryBoard.com (blog)

Pharmacotherapy for borderline personality disorder: Cochrane systematic ...  -  ‎Dec 31, 2009‎
...future: most ongoing trials are testing different drugs, such as the SGA quetiapine, the SSRI sertraline or the opioid receptor antagonist naltrexone. ... British Journal of Psychiatry

Depression in adults with long term conditions 2: antidepressant and ...  -  ‎Dec 14, 2009‎
In general, an SSRI antidepressant in generic form, such as citalopram or sertraline, should be prescribed first because of low tendency for interactions ... Nursing Times

Brain serotonin-2 receptors in acute mania  -  ‎Dec 31, 2009‎
Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, ... British Journal of Psychiatry

Omega-3 showed no benefit for depression in patients with CHD  -  ‎Oct 22, 2009‎
Despite previous studies showing otherwise, the addition of omega-3 fatty acids with sertraline did not improve depression outcomes in patients with ... Endocrine Today

Vital Signs Regimens: A Supplement Didn't Help Heart Patients  -  ‎Nov 2, 2009‎
In a clinical trial, two groups of heart patients taking the antidepressant sertraline (Zoloft) were randomly assigned to receive a supplement of either ... New York Times

A Double-blind Randomized Controlled Trial of Olanzapine Plus Sertraline vs ...  -  ‎Nov 2, 2009‎
Intervention Target doses of 15 to 20 mg of olanzapine per day plus masked sertraline or placebo at 150 to 200 mg per day. Main Outcome Measure Remission ... Archives of General Psychiatry

Omega-3 Augmentation of Sertraline in Treatment of Depression in Patients With ...  -  ‎Oct 27, 2009‎
Study Question: Do omega-3 fatty acids augment sertraline in the treatment of depression in patients with coronary heart disease (CHD)? ... Cardiosource

Which Antidepressants Treat Comorbid Anxiety and Depression?  -  ‎Oct 28, 2009‎
Is sertraline the best anxiolytic of the antidepressants? What other agents are available for concomitant anxiety and depression? About 25% of individuals ... Medscape

Regimens: Omega-3 Fats Fail to Lift Depression in Heart Patients  -  ‎Oct 26, 2009‎
The patients were randomly assigned to a combination of sertraline, an anti-depressant, and either omega-3s or a corn oil placebo. After 10 weeks, there was ... New York Times

The Role of Antidepressants for the Treatment of Bipolar Depression  -  ‎Nov 4, 2009‎
Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, ... Psychiatric Times

On the Pulse - 30th October 2009  -  ‎Oct 30, 2009‎
So perhaps it makes sense to try adding supplements of eicosapentaenoic and docosahexaenoic acids to sertraline when treating patients suffering from both ... OnMedica

What Did STAR*D Teach Us? Results From a Large-Scale, Practical, Clinical ...  -  ‎Oct 30, 2009‎
Nearly one-quarter of patients achieved remission when switched to measurement-based care-guided treatment with sertraline (a "within class" SSRI switch), ... Psychiatric Services (subscription)

Are antidepressants affecting your sex drive?  -  ‎Nov 10, 2009‎
This class includes Prozac (fluoxetine), Zoloft (sertraline), Paxil (paroxetine) and others. SSRIs work by helping to restore the right balance of the brain ... KIVI-TV

Spokesperson Alert: Natural Products Association Spokesperson Available for ...  -  ‎Oct 19, 2009‎
..."This is a study on augmenting sertraline, an antidepressant prescription medication, with a nutritional product, omega-3 fatty acids," said, Fabricant. ... Reuters

Ulceration of the oral mucosa induced by antidepressant medication: a case report  -  ‎Nov 3, 2009‎
...referred by her dentist to our outpatient clinic with a 4-week history of an oral ulceration after using an antidepressant (sertraline hydrochloride). ... 7thSpace Interactive (press release)

Dispenser loses appeal against error conviction  -  ‎Oct 29, 2009‎
Georgina Mahoney, of Lloydspharmacy, Prestatyn, was rightly convicted and fined for her part in a patient being given antidepressant sertraline instead of a ... Chemist+Druggist

New Report Just Published Blood-Brain Barrier: Bridging Options for Drug ...  -  ‎Oct 23, 2009‎
These include Pfizer's Zoloft (sertraline, for treatment of depression and certain types of anxiety disorders), Lilly's Cymbalta (duloxetine, for treatment ... Live-PR.com (Pressemitteilung)

Chồng giữ cương lâu, vợ không “tá»± sướngâ€?  -  ‎Nov 9, 2009‎
Nhóm thuốc ức chế tái hấp thu serotonine có chá»?n lá»?c (SSRIs) như Sertraline, Paroxetin: làm ức chế phản xạ xuất tinh, kéo dài thá»?i gian trước khi xuất tinh. ... XãLuận.com tin tức việt nam 24h cập nhật

'심장병+우울ì¦?' 오메가-3-지방산 ë³´ì¶© ë?„움 안 ë?œë‹¤  -  ‎Oct 22, 2009‎
...그러나 122명 환ìž?를 대ìƒ?으로 오메가-3-지방산ì?„ 보충해주는 것ì?´ ê´€ìƒ?ë?™ë§¥ì‹¬ìž¥ì§ˆí™˜ê³¼ 우울ì¦?ì?´ ë?™ë°˜ë?œ 환ìž?ì—?서 우울ì¦? 치료제ì?¸ 졸로프트등ì?˜ 서트랄린(sertraline) ... 메디컬투데이

Ð’ гармонии Ñ? гормонами  -  ‎Oct 25, 2009‎
ЕÑ?ли речь идет о кормÑ?щей матери, Ñ?ледует выбирать препараты, малаÑ? чаÑ?ть которых попадает в грудное молоко (такие как sertraline hydrochloride - הלוסטרל), ... IsraelInfo.ru

India Lupin gets US FDA nod for sertraline tablets  -  Feb 7, 2007
MUMBAI, Feb 7 (Reuters) - Indian drug maker Lupin Ltd. (LUPN.BO) said on Wednesday it had got approval of the US Federal Drug Administration to sell ... Reuters

Therapy plus Zoloft helps ease kids' anxiety  -  Oct 30, 2008
Combining the drug sertraline, available as a generic and under the brand name ... Sertraline is among antidepressants linked with suicidal thoughts and ... msnbc.com

Efficacy of sertraline hydrochloride in treatment of premature...  -  Dec 12, 2005
Correspondence: Dr R Shamloul, Department of Andrology, Cairo University Hospital, El-Manial, Cairo 202, Egypt. E-mail: rannone74@hotmail.com ... Nature.com

FDA Approves First Generic Sertraline  -  Jul 1, 2006
As part of the Food and Drug Administration's (FDA) on-going efforts to increase the available generic drug alternatives for American consumers, ... Kansas City infoZine

AUROBINDO PHARMA GETS USFDA NOD FOR SERTRALINE …  -  Sep 27, 2005
Aurobindo Pharma Ltd., has announced that US Food Drug Administration (US FDA) has tentatively approved its Sertraline Hydrochloride ANDA for Tablets 25 mg ... Pay-Per-View - Hindustan Times - Factiva, from Dow Jones

Atlanta Metro News | ajc.com  -  Nov 3, 2008
Combining the drug sertraline, available as a generic and under the brand name ... Sertraline is among antidepressants linked with suicidal thoughts and ... Atlanta Journal Constitution

Prozac is linked to low sperm count  -  Oct 24, 2006
The second was on sertraline, which is sold as Lustral in Britain. ... A clinical trial has begun of 30 men taking sertraline. ... Times Online

Kmart adds more generic drugs to 90-day program  -  Jul 11, 2007
Kmart also now offers sertraline, which is used to treat depression, ... Sertraline and simvastatin are not on the list of drugs available for $4 at ... Reuters

Aurobindo gets UK MHRA nod for Sertraline  -  Nov 1, 2005
Aurobindo Pharma Limited has announced that it has received the marketing authorisation approval from UK MHRA (United Kingdom Medicines and Healthcare ... Business Standard

India's Wockhardt wins FDA OK to launch generic version of Pfizer's...  -  Jan 9, 2008
50 and 100 mg in the US within the next few weeks. The company quoted data stating that the total market for Sertraline tablets in the US is 1.1 bln usd. Forbes

Lupin gets USFDA nod for Sertraline  -  Jan 2, 2007
PTI. JANUARY 2: City-based domestic drug maker Lupin said USFDA has granted tentative approval for the company's Abbreviated New Drug Application (ANDA) for ... Financial Express

Sertraline (Systemic).  -  Feb 1, 2006
Sertraline ( SER-tra-leen) is used to treat mental depression, obsessive-compulsive disorder, panic disorder, premenstrual dysphoric disorder, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Zydus Cadila to sell Sertraline in France  -  Nov 22, 2005
Zydus Cadila Healthcare Ltd [ Get Quote ] on Tuesday said it has received approval from the French regulatory agency, AFSSAPS, to market Sertraline capsules ... Rediff

Teenager dies from anorexia three years after being prescribed drug...  -  Nov 4, 2008
Charlotte was prescribed sertraline, an anti-depressant, in September 2004. Photo: B-EAT.CO.UK. Student Charlotte Robinson, of Worstead, Norfolk, ... Telegraph.co.uk

Depressed 'recover poorly after heart attacks'  -  Sep 4, 2007
It found patients who are treated for their depression with sertraline, an anti-depressant, experienced on average a nine per cent increase in heart rate ... Telegraph.co.uk

Sertraline (Systemic).(Drug overview)  -  May 1, 2006
Sertraline ( SER-tra-leen) is used to treat mental depression, obsessive-compulsive disorder, panic disorder, premenstrual dysphoric disorder, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Use of sertraline, paroxetine and fluvoxamine by nursing women  -  May 1, 2005
Declaration of interest This study was supported by the National Institute of Mental Health, Smith Kline Beecham and Pfizer. ... British Journal of Psychiatry (subscript...

Sertraline does not improve symptoms in some cancer patients without ...  -  Jun 5, 2007
The established antidepressant sertraline does not improve symptoms, wellbeing or survival in patients with advanced cancer who do not have major depression ... News-Medical.net

Sertraline may not be effective in preventing post-stroke depression.(...  -  Oct 1, 2006
There is still no clear evidence that pharmacotherapy can prevent depression in post-stroke patients. According to new study results, treating non-depressed ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

… receives final approval for Sertraline Hydrochloride Oral Concentra...  -  Nov 10, 2008
Sertraline Hydrocholride Oral Concentrate is the generic equivalent of Pfizer's Zoloft Oral Concentrate, which is indicated for the treatment of major ... Equity Bulls

Ranbaxy Gains Final US FDA Approval For Sertraline Hydrochloride …  -  Feb 9, 2007
Ranbaxy Laboratories Ltd (RLL), announced that the Company has received approval from the US Food and Drug Administration (FDA) to manufacture and market ... Lifescience-online

… Biomarkers and Plasma Levels of Sertraline and N-Desmethylse  -  Jun 12, 2005
Concentrations of sertraline and N- desmethylsertraline were determined by liquid ... Sertraline is one of three SSRIs (the others are fluvoxamine and ... RedOrbit

Anti-depressants not for cancer  -  Nov 30, 2006
..."Half the trial participants took sertraline...while the other half took a placebo that looked the same but had no sertraline in it,'' Prof Stockler said. ... NEWS.com.au

Actavis Launches Sertraline Tablets in the US  -  Feb 7, 2007
Sertraline Hydrochloride tablets, the generic equivalent of Pfizer's Zoloft tablets, are available in 25mg, 50mg and 100 mg strengths. ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

Depression (PDQ®)  -  Dec 19, 2008
Treatment with sertraline is sometimes complicated by dyspepsia, tremor, ... 23] Sertraline and paroxetine have a half-life of approximately 20 hours; thus, ... WebMD

Sertraline may improve itching in liver disease.  -  Jan 15, 2006
SAN FRANCISCO -- The SSRI sertraline improved pruritus from cholestatic liver disease in a small double-blind crossover study of 12 patients, Dr. Marlyn J. ... Free with registration - Internal Medicine News - AccessMyLibrary.com

… of cholestatic pruritus with sertraline.(CLINICAL TRIAL REVIEW)  -  Sep 1, 2005
This study is currently recruiting patients. Sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com

… , Inc. Announces the Launch of Sertraline Hydrochloride Tablets,...  -  Feb 7, 2007
Sertraline Hydrochloride Tablets had total annual sales of approximately $3.07 ... Full prescribing information for Sertraline Hydrochloride Tablets, 25mg, ... Free with registration - PR Newswire - AccessMyLibrary.com

Teva begins sale of generic version of Zoloft (Sertraline) tablets,...  -  Sep 7, 2006
Teva Pharmaceutical Industries Ltd. (TEVA) announced that it has begun the sale of its generic version of Pfizer's Zoloft (Sertraline) tablets, 25 mg, ... TMC Net

Agomelatine Appears Superior to Sertraline for Treatment of Major …  -  Sep 2, 2008
By Judith Moser, MD. BARCELONA, Spain -- September 2, 2008 -- Agomelatine improves outcomes more effectively than sertraline in patients with major ... DG News

Mixed results with sertraline for panic disorder.(What's New in...  -  Dec 1, 2005
In a randomized withdrawal study published in the October issue of International Clinical Psychopharmacology, researchers found that sertraline (Zoloft) ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Article: Lupin gets USFDA nod for sertraline tablets. - Economic...  -  Jan 3, 2007
Lupin gets USFDA nod for sertraline tablets. ... find Economic Times (New Delhi, India) articles. Byline: Gireesh Prasad Jan. 3--MUMBAI, India -- Lupin Ltd ... Pay-Per-View - Economic Times - HighBeam Research

Mixed result with sertraline for panic disorder.(What's New in...  -  Feb 1, 2006
In a randomized withdrawal study published in the October issue of International Clinical Psychopharmacology, researchers found that sertraline (Zoloft) ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Sertraline Ineffective for Menopausal Hot Flashes  -  Feb 15, 2008
Background: More than one half of women report hot flashes during menopause. For about 20 percent of these women, symptoms are sufficiently severe to ... AAFP News Now

Sertraline study: alcohol subtype an important treatment consideration...  -  May 1, 2005
A follow-up study evaluating the posttreatment effect of sertraline pharmacotherapy for alcohol dependence showed that patients with lower severity who ... Free with registration - Brown University Digest of Addiction... - AccessMyLibrary.com

Liothyronine Plus Sertraline May Be Helpful for Major Depression  -  Jun 8, 2007
June 8, 2007 -- In patients with major depressive disorder, liothyronine added to sertraline may be helpful in those most likely to benefit from combined ... Medscape

… controlled general practice trial of sertraline, exposure therapy...  -  Mar 1, 2008
Aims To examine the efficacy of sertraline or exposure therapy, ... Patients (n = 387) received sertraline 50-150 mg or placebo for 24 weeks. ... British Journal of Psychiatry (subscript...

… raises patients' response to sertraline.(treating depression) -...  -  Nov 1, 2006
...[T.sub.3] supplementation raises patients' response to sertraline.(treating depression) ... find Clinical Psychiatry News articles. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Sertraline (Zoloft) Relieves Pruritus in Cholestatic Liver Disease: …  -  Nov 17, 2005
By Crystal Phend. SAN FRANCISCO, CA -- November 17, 2005 -- The antidepressant sertraline (Zoloft) appears to relieve itching from cholestatic liver disease ... DG News

05/21/07 #5 - Doctor says no Imigran (Imitrex) with sertraline (Zoloft...  -  May 21, 2007
However, I have been put on Sertraline (Zoloft) 150mg (antidepressant) and I can no longer have Imigran, and my GP has given me Clotam 200mg. ... HealthCentral.com

… Tentative FDA Approval for Sertraline Hydrochloride Tablets. - PR ...  -  Dec 8, 2005
Alpharma Receives Tentative FDA Approval for Sertraline Hydrochloride Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Medication may cut depression in diabetics  -  May 8, 2006
...diabetes, who averaged just over 50 years of age, and all had recovered from an episode of depression following treatment with sertraline, or Zoloft. ... United Press International

Adding sertraline to CBT for PTSD: benefits questionable.(What's New...  -  Sep 1, 2007
According to findings from a small clinical trial, sexually abused children and adolescents with post-traumatic stress disorder (PTSD) should receive ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

New Hope For The Sad Heart: SADHART Clinical Trial Presents …  -  Sep 23, 2008
..."Safety and Efficacy of Sertraline for Depression in Patients with CHF: SADHART-CHF Trial," a ... "Sertraline has a very favorable pharmacological profile, ... Medical News Today - Medical News Today (press release)

Possible association of tics with escitalopram and sertraline.(Case...  -  Jun 1, 2005
Sertraline was begun. During sertraline treatment, the patient's panic disorder ... After approximately 3 weeks of sertraline treatment she again began to ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Sertraline improved itching from liver disease in small study.(Across...  -  Mar 1, 2006
Sertraline improved itching from liver disease in small study.(Across Specialties) ... find Clinical Psychiatry News articles. SAN FRANCISCO -- The SSRI ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

… Announces Final FDA Approval for Sertraline Hydrochloride Tablets....  -  Feb 6, 2007
Mylan Announces Final FDA Approval for Sertraline Hydrochloride Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

A closer look .  -  Aug 22, 2005
Each patient was given one of five drugs over an eight-week period: sertraline. otogenic and psychogenic dizziness responded best to the medication. ... Milwaukee Journal Sentinel - Google News Archive

Triiodothyronine enhances response to sertraline.(Mental Health)  -  Nov 1, 2006
PARIS -- Triiodothyronine supplementation significantly increased the antidepressant effects of sertraline in a randomized placebo-controlled clinical trial ... Free with registration - Family Practice News - AccessMyLibrary.com

Article: Sertraline may improve itching in liver disease. - Internal...  -  Jan 15, 2006
Sertraline may improve itching in liver disease. ... find Internal Medicine News articles. SAN FRANCISCO -- The SSRI sertraline improved pruritus from ... Pay-Per-View - Internal Medicine News - HighBeam Research

Zoloft - Sertraline hydrochloride - Medical Drug  -  Mar 10, 2008
Zoloft is thought to work by preventing the reuptake of a certain chemical called serotonin back into the brain cells. Serotonin is widely recognised to be ... Virtual Medical Centre - The Virtual Medical Centre

Sertraline, a serotonin-uptake inhibitor, reduces food intake and...  -  Apr 5, 2005
Sertraline was found to inhibit weight gain and decrease food intake without affecting locomotion in rats and genetically obese (ob/ob) mice. ... Am J Clin Nutr (subscription)

… : Ranbaxy Gains Final Approval for Sertraline Hydrochloride...  -  Feb 8, 2007
Ranbaxy Gains Final Approval for Sertraline Hydrochloride Tablets. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… Required When Coadministering Sertraline and Ramelteon: Presented...  -  Sep 18, 2006
By Maria Bishop. BOSTON, MASSACHUSETTS -- September 18, 2006 -- Depressed patients taking the selective serotonin-reuptake inhibitor (SSRI) sertraline may ... DG News

Depression and heart recovery  -  Jul 3, 2008
Sertraline increases HRV compared to placebo, and improvements in depression are also associated with increased HRV. What does the NHS Knowledge Service ... Scotsman

… AUROBINDO GETS USFDA TENTATIVE APPROVAL FOR SERTRALINE …  -  Sep 28, 2005
MUMBAI, Sept 28 Asia Pulse - Aurobindo Pharma Ltd (BSE:524804) said it has received tentative approval from the US FDA for its Sertraline Hydrochloride ANDA ... $4.95 - AsiaPulse News - ECNext

… in bipolar depression with venlafaxine, sertraline and bupropion.(W...  -  Jun 1, 2006
The average maximum doses achieved in the acute phase were 268 [+ or -] 132 mg/day for bupropion, 192 [+ or -] 104 mg/day for sertraline and 195 [+ or ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Sertraline response varies with age in depressed children, teens.( …  -  Dec 1, 2006
Children aged 6-11 years with major depressive disorder have a significantly faster first response to both sertraline and a placebo, compared with ... Free with registration - Pediatric News - AccessMyLibrary.com

Sertraline-induced hyponatremia in the elderly.(LETTERS / COURRIER)( …  -  Nov 1, 2007
The causative agent was found to be the SSRI, sertraline. ... Sertraline-induced hyponatraemia, although relatively uncommon, is an important clinical ... Free with registration - Canadian Journal of Emergency Medicine - AccessMyLibrary.com

Combination Sertraline-Alprazolam May Provide Both Short- and Long- …  -  Mar 22, 2005
By Bonnie Darves. SEATTLE, WA -- March 22, 2005 -- Patients with moderate to severe panic disorder may benefit from a novel combination treatment that ... DG News

Aurobindo Pharma bags South African approval for Sertraline tablets  -  Dec 15, 2006
Aurobindo Pharma (Q, N,C,F)* said Friday that it received another marketing authorization approval from medicines control council (MCC) of South Africa for ... Myiris.com

… Therapy; Hot flashes may be reduced with sertraline (Zoloft)...  -  Apr 24, 2006
Our objective was to assess the effect of sertraline on the frequency and severity of hot flashes, mood status, and health-related quality of life." ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Antidepressant Medication May Prevent Recurring Depression in …  -  May 3, 2006
Participants taking sertraline were significantly less likely to develop an ... After one year, 65.8 percent of the patients taking sertraline remained in ... DG News

Perrigo Company Announces Tentative Approval for Sertraline …  -  Feb 22, 2006
...it has received tentative approval from the US Food and Drug Administration (FDA) to market Sertraline Hydrochloride Tablets, 25 mg, 50 mg and 100 mg. ... $4.95 - PR Newswire - ECNext

News: High anxiety?. Genetic Engineering & Biotechnology News - …  -  Apr 18, 2008
The new study will test a generic form of the drug Zoloft (sertraline), a selective serotonin reuptake inhibitor (SSRI) approved by the US Food and Drug ... Genetic Engineering News - Genetic Engineering News (press release)

Study Shows Positive Results for Pramipexole in Parkinson's Disease …  -  Aug 23, 2006
The study, which did not include a placebo arm, found that after 12 weeks of treatment, patients in both the Mirapex- and sertraline-treated groups achieved ... DG News

PATENT LAW FOMENTS A GENERIC REVOLUTION Drug companies' …  -  Aug 8, 2007
Prescription bottles bearing catchy brand names like Zoloft and are being pushed aside by tongue-twisting generics like sertraline and fluticasone ... Sarasota Herald-Tribune - Google News Archive

Teva Files Patent Infringement Complaints Regarding Sertraline …  -  Jan 24, 2007
...of finished dose companies which manufacture sertraline hydrochloride, AB rated to Zoloft(R), ... covering processes of making sertraline hydrochloride. ... Genetic Engineering News - Genetic Engineering News (press release)

VAS-COG: Sertraline Shows Promise for Improving Executive Function in...  -  Jul 16, 2007
Reviewed by Zalman S. Agus, MD; Emeritus Professor at the University of Pennsylvania School of Medicine. SAN ANTONIO -- High-dose therapy with the selective ... Psychiatric Times

Sertraline: a dual-action antidepressant?(Back to Basics)(Brief...  -  Jul 1, 2005
Sertraline: a dual-action antidepressant?(Back to Basics)(Brief article) ... find Psychopharmacology Educational Updates (PsychEd Up) articles. Pay-Per-View - Psychopharmacology Educational Updates - HighBeam Research

Triiodothyronine enhances response to sertraline.(Mental Health) |...  -  Nov 1, 2006
Triiodothyronine enhances response to sertraline.(Mental Health) ... find Family Practice News articles. PARIS -- Triiodothyronine supplementation ... Pay-Per-View - Family Practice News - HighBeam Research

Triiodothyronine enhances response to sertraline.(Psychiatry)  -  Jan 1, 2007
PARIS -- Triiodothyronine supplementation significantly increased the antidepressant effects of sertraline in a randomized placebo-controlled clinical trial ... $4.95 - Internal Medicine News - ECNext

… enhances response to sertraline.(Psychiatry) | Article from...  -  Jan 1, 2007
Triiodothyronine enhances response to sertraline.(Psychiatry) ... find Internal Medicine News articles. PARIS -- Triiodothyronine supplementation ... Pay-Per-View - Internal Medicine News - HighBeam Research

Antidepressants not useful in cancer  -  Jun 6, 2007
June 6, 2007 (Insidermedicine) Treating cancer patients without major depression with the antidepressant sertraline does not improve symptoms, wellbeing or ... Insidermedicine

Zydus Cadila gets approval for Sertraline from AFSSAPS  -  Dec 31, 2005
Zydus Cadila has received approval from the AFSSAPS, the French regulatory agency to market Sertraline capsules 25 mg and 50 mg. The drug falls into the CNS ... expresspharmapulse.com

Alpharma Receives Tentative FDA Approval for Sertraline Hydrochloride...  -  Dec 8, 2005
Alpharma's sertraline hydrochloride tablets are the AB-rated generic equivalent of Pfizer's Zoloft(R) tablets, a product indicated for several disorders, ... Free with registration - PR Newswire - AccessMyLibrary.com

VAS-COG: Sertraline Shows Promise for Improving Executive Function in...  -  Jul 16, 2007
Reviewed by Zalman S. Agus, MD; Emeritus Professor at the University of Pennsylvania School of Medicine. Patients selected for the program are treated with ... Psychiatric Times

Group CBT as effective as sertraline.(CLINICAL CAPSULES)(cognitive- …  -  Dec 1, 2005
Children and adolescents aged 9-17 years with obsessive-compulsive disorder demonstrated equally significant symptom reductions after being randomized to 12 ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Zydus Cadila to market Sertraline Hydrochloride tablets in US  -  Mar 2, 2006
Mumbai, Mar 1 (PTI) Pharma major Zydus Cadila has received tentative approval from the USFDA to market Sertraline Hydrochloride Tablets in the US market, ... Free with registration - PTI - The Press Trust of India Ltd - AccessMyLibrary.com

Press Release: Actavis Launches Sertraline Tablets in the US - PR …  -  Feb 7, 2007
Actavis Launches Sertraline Tablets in the US from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Safe Meds for Postpartum Depression? | Psych Central News  -  Aug 16, 2006
They were randomized to receive either nortriptyline or sertraline. ... By week four, 46 percent of the participants taking sertraline had responded and 27 ... PsychCentral.com

Diagnostics; Novel voltammetric method detects sertraline in flow at ...  -  Nov 22, 2005
2005 NOV 22 - (NewsRx.com) -- The detection of sertraline in flow was accomplished at a reduced costs using a novel voltammetric method. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Perrigo Company Announces Tentative Approval for Sertraline …  -  Feb 22, 2006
...it has received tentative approval from the US Food and Drug Administration (FDA) to market Sertraline Hydrochloride Tablets, 25 mg, 50 mg and 100 mg. ... RedOrbit

Sertraline and fluoxetine are effective for treating PTSD.(Psychiatry)...  -  Nov 1, 2007
Sertraline and fluoxetine are effective for treating PTSD.(Psychiatry)(posttraumatic stress disorder) ... find Internal Medicine News articles. Pay-Per-View - Internal Medicine News - HighBeam Research

Response to sertraline varies with age.(CLINICAL CAPSULES)(Brief …  -  Dec 1, 2006
Response to sertraline varies with age.(CLINICAL CAPSULES)(Brief article) ... find Clinical Psychiatry News articles. Children aged 6-11 years with major ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Sertraline staves off depression.(Clinical Capsules)  -  Jun 1, 2006
Maintenance therapy with sertraline prevents a recurrence of major depression in diabetic patients whose mood disorder initially responds well to the drug, ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

Sertraline, fluoxetine help PTSD patients, reviews show.(Adult...  -  Dec 1, 2007
Sertraline, fluoxetine help PTSD patients, reviews show.(Adult Psychiatry) ... find Clinical Psychiatry News articles. HONOLULU -- Selective serotonin ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

New Findings in Childhood Obsessive-Compulsive Disorder  -  Feb 1, 2006
Youths in the sertraline treatment group were administered sertraline 25 mg/day ... The mean dose of sertraline in the acute phase of treatment was 137.5 mg ... Pay-Per-View - Psychiatric Times - Factiva, from Dow Jones

… of cognitive-behavioral therapy, sertraline, and their combination...  -  Oct 1, 2006
Objective: To evaluate cognitive-behavioral therapy, antidepressant medication alone, and combined CBT and antidepressant medication in the treatment of ... Pay-Per-View - Journal of the American Academy of... - Factiva, from Dow Jones

… , Inc. Announces the Launch of Sertraline Hydrochloride Tablets,...  -  Feb 7, 2007
Roxane Laboratories, Inc. Announces the Launch of Sertraline Hydrochloride Tablets, 25mg, 50mg, 100mg. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

EBSCOhost Connection: Sertraline Induced Systemic Lupus …  -  Jul 1, 2006
SERTRALINE DRUGS -- Side effects IMMUNOLOGIC diseases ... Sertraline Induced Systemic Lupus Erythematosus Sertraline Induced Systemic Lupus Erythematosus ... Subscription - Internet Journal of Asthma, Allergy and... - EBSCO Publishing

Cognitive-behavioural therapy better than sertraline in treating...  -  Dec 22, 2006
Cognitive-behavioural group therapy (CBGT) and sertraline (Zoloft) have both proven effective in treating obsessive-compulsive disorder (OCD), ... $4.95 - CrossCurrents - The Journal of Addiction... - ECNext

14 News, The Tri-State's News and Weather Leader-Zoloft Helps …  -  May 1, 2006
..."Our study establishes a clear benefit of sertraline for prevention of ... "Sertraline lengthened the depression-free interval of maintenance and did not ... WFIE-TV

Unexpected results from SADHART: in over half of cases depression …  -  Aug 1, 2006
Unexpected results from the Sertraline Antidepressant Heart Attack ... Sertraline (Zoloft) was found to be more effective than placebo in subjects with MDD ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Treatments and drugs  -  Aug 8, 2008
Selective serotonin reuptake inhibitors such as paroxetine (Paxil), fluoxetine (Prozac) and sertraline (Zoloft) also have been successful in preventing ... MayoClinic.com

Article: Sertraline response varies with age in depressed children,...  -  Dec 1, 2006
Sertraline response varies with age in depressed children, teens.(Behavioral Pediatrics) ... find Pediatric News articles. Children aged 6-11 years with ... Pay-Per-View - Pediatric News - HighBeam Research

Dr. Reddy's Q2 FY07 Revenue at Rs 20,039 Million.  -  Oct 27, 2006
This decline was primarily due to decrease in revenues from sertraline and ibuprofen partially offset by increase in sales of development products. ... Free with registration - Business Wire - AccessMyLibrary.com

Teva Launches First Generic Zoloft and Bristol-Myers Files Motion to...  -  Aug 16, 2006
Zoloft is made by New York-based Pfizer Inc. Because Teva was the first generic company to file for US regulatory approval to sell generic sertraline, ... Free with registration - M2 Presswire - AccessMyLibrary.com

Article: In kids, response to sertraline varies with age.(Mental...  -  Dec 1, 2006
In kids, response to sertraline varies with age.(Mental Health) ... find Family Practice News articles. children with major depressive disorder aged 6-11 ... Pay-Per-View - Family Practice News - HighBeam Research

… Receives US FDA Approval for Sertraline. - PR Newswire | HighBeam ...  -  Feb 7, 2007
Lupin Receives US FDA Approval for Sertraline. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Brand Names/Synonyms:
Sertraline is also known by the following brand names and/or synonymsApo-Sertraline; HSDB 7037; Lustral; Sertralina [Spanish]; Sertraline; Sertraline Hydrochloride; Sertralinum [Latin]; Sultamicillin Tosylate; Zoloft

Drug Category:
Sertraline is categorized under the following by the FDA: Antidepressants; Selective Serotonin Reuptake Inhibitors (SSRIs); ATC:N06AB06

Dosage Forms:
Tablets and Oral solution

Absorption:
The effects of food on the bioavailability of the sertraline tablet and oral concentrate were studied in subjects administered a single dose with and without food. For the tablet, AUC was slightly increased when drug was administered with food but the Cmax was 25% greater, while the time to reach peak plasma concentration (Tmax) decreased from 8 hours post-dosing to 5.5 hours. For the oral concentrate, Tmax was slightly prolonged from 5.9 hours to 7.0 hours with food.

Interactions:
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Chemical IUPAC Name:
4-(3,4-dichlorophenyl)-N-methyl-tetralin-1-amine





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