Sevoflurane

This page contains recent news articles, when available, and an overview of Sevoflurane but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Sevoflurane
(when available)

Pharmacology and use:
Sevoflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential. Used for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery

Mechanism Of Action:
Sevoflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Sevoflurane also activates calcium dependent ATPase in the sarcoplasmic reticulum by increasing the fluidity of the lipid membrane. Also appears to bind the D subunit of ATP synthase and NADH dehydogenase. Sevoflurane also binds to the GABA receptor, the large conductance Ca2+ activated potassium channel, the glutamate receptor and the glycine receptor.

News Articles on Sevoflurane

Single Celled Organism Helps In Understanding How Anesthesia Works  -  ‎Dec 23, 2009‎
...both inhaled anesthetics, like desflurane, halothane, isoflurane, sevoflurane, and xenon; and intravenous anesthetics, like propofol and etomidate. ... Medical News Today (press release)

Composite Variability Index of Intraoperative Somatic Events Similar With ...  -  ‎Oct 20, 2009‎
The researchers wanted to compare the relation of CVI with somatic responses for propofol/remifentanil and sevoflurane/remifentanil, according to Donald ... DG News

Piramal's critical care business looking at $100m sales  -  ‎Nov 3, 2009‎
Inhalation anaesthetics are gasses that possess anaesthetic qualities like halothane, isoflurane, desflurane, sevoflurane and enflurane. ... Daily News & Analysis

Wastage of Supplies and Drugs in the Operating Room  -  ‎Oct 22, 2009‎
Fortunately, the two most commonly used anesthesia gases, sevoflurane and desflurane, contain neither chloride nor bromide, and thus should not pose a ... Medscape

Dextrose solution decreases postoperative nausea and vomiting  -  ‎Oct 25, 2009‎
All patients underwent a sevoflurane-vecuronium general anesthesia and received one dose of an antiemetic, a drug effective against nausea and vomiting 30 ... News-Medical.net

Court: Abbott Sevoflurane Patent Invalid In Baxter Case  -  Nov 9, 2006
CHICAGO -(Dow Jones)- A US appeals court said Thursday that an Abbott Laboratories Inc. (ABT) patent covering the formulation of a inhaled anesthetic called ... CNNMoney.com

Baxter Launches First Sevoflurane in China and Announces Phased …  -  Dec 12, 2005
DEERFIELD, Ill., Dec. 12 /PRNewswire/ -- Baxter Healthcare Corporation announced today the launch of sevoflurane, the world's most widely-used inhaled ... biotech-intelligence.com

Piramal Healthcare acquires NY based Pain Management Co, Minrad Intl  -  Dec 23, 2008
Piramal will get an immediate entry into the US market for sevoflurane, the largest selling inhalation drug in the US. Piramal Healthcare Limited, one of ... Reuters India

BATTLE OVER ANESTHETIC: Baxter's version OK, judge says; Abbott …  -  Sep 24, 2005
Sevoflurane earned Abbott more than $750 million in sales last year, ... Deerfield-based Baxter first developed sevoflurane in the 1970s and signed over the ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Anaesthetic drug 'numbs memory'  -  Apr 12, 2008
The University of California scientists found that sevoflurane gas stopped ... However, those who had received sevoflurane could remember just 5% of the ... BBC News

Sevoflurane (Inhalation-Systemic).(Drug overview)  -  May 1, 2006
Sevoflurane (see-voe-FLOO-rane) belongs to the group of medicines known as general anesthetics ( an-ess-THET-iks ). Sevoflurane is used to cause general ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

RxElite Announces Launch of Generic Sevoflurane.  -  Jul 23, 2007
MERIDIAN, Idaho, July 23 /PRNewswire-FirstCall/ -- Southridge Technology Group, Inc. (BULLETIN BOARD: SOUT) announced that its wholly owned operating ... Free with registration - PR Newswire - AccessMyLibrary.com

MINRAD International, Inc. Announces Japanese Approval of Sevoflurane...  -  Mar 20, 2007
ORCHARD PARK, NY, March 20 /PRNewswire/ -- MINRAD International, Inc. today announced that its exclusive distribution partner in Japan, Merck Seiyaku, ... Free with registration - PR Newswire - AccessMyLibrary.com

Sevoflurane (Inhalation-Systemic).  -  Feb 1, 2006
Sevoflurane (see-voe-FLOO-rane) belongs to the group of medicines known as general anesthetics ( an-ess-THET-iks ). Sevoflurane is used to cause general ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Deeper losses for Minrad Business First of Buffalo  -  Nov 13, 2007
Minrad International Inc. reported Tuesday substantially increased losses and declining revenues in the third quarter on reduced sales of Sevoflurane and ... Bizjournals.com

Press Release: Baxter Launches First Sevoflurane in China and …  -  Dec 12, 2005
Baxter Launches First Sevoflurane in China and Announces Phased Launch in Other Countries in 2006. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

RXElite Holdings 'surprised' by Minrad's move  -  Sep 13, 2008
Minrad in June launched a direct selling effort for its sevoflurane and isoflurane anesthesia products in the US veterinary market. Buffalo News

SEVOFLURANE (Inhalation, oral/nebulization route) - see-voe-FLOO- …  -  May 1, 2007
Sevoflurane belongs to the group of medicines known as general anesthetics ( ). Sevoflurane is used to cause general anesthesia (loss of consciousness) ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Isoflurane Shown Superior to Sevoflurane and Desflurane after Cardiac...  -  Oct 24, 2005
By Mike Fillon. ATLANTA, GA -- October 24, 2005 -- A study presented here at the American Society of Anesthesiologists (ASA) Annual Meeting shows that use ... DG News

Comparison of propofol and sevoflurane for laryngeal mask airway …  -  Apr 1, 2007
Background: Sevoflurane and propofol have been widely used for anesthesia induction. This study compared the efficacies of sevoflurane and propofol ... $4.95 - Southern Medical Journal - ECNext

Angiotensin; Aortic smooth muscle contraction examined, sevoflurane …  -  Sep 13, 2005
..."Sevoflurane dilates blood vessels and reduces arterial blood pressure in a ... "We designed this study to examine the effects of sevoflurane on Ang ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

IOP measurements in kids more accurate using ketamine vs. sevoflurane...  -  Apr 2, 2007
Sedating children using sevoflurane gas significantly lowers the IOP measured ... They found that the measured IOP of eyes in the sevoflurane group was ... OSN SuperSite

Anesthesia; Sevoflurane anesthesia can significantly impair …  -  Jun 27, 2006
The researchers concluded, "Anesthesia with sevoflurane may lead to significantly impaired bronchociliary clearance in comparison to TIVA. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… opioid peptide receptors are involved in sevoflurane-induced...  -  Nov 8, 2005
The aim of this study was to observe the effects of sevoflurane on pain processing ... "In rats with transected spinal cord, sevoflurane produced a profound ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

… FDA Approval of Petrem(TM) Sevoflurane. - PR Newswire | Hig  -  Jun 9, 2008
MINRAD International, Inc. Announces FDA Approval of Petrem(TM) Sevoflurane. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… States Code of Federal Regulations - 21 CFR § 529.2150 Sevoflurane.  -  Jul 11, 2006
For induction of surgical anesthesia: up to 7 percent sevoflurane. For maintenance of surgical anesthesia: 3.7 to 4 percent sevoflurane with oxygen in the ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

… . Announces Validation Completion of its New Sevoflurane API Line. ...  -  Dec 10, 2007
The addition of the Sevoflurane API line will increase the capacity of MINRAD's Bethlehem ... With validation of the new Sevoflurane API line complete, ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Baxter Prevails in Sevoflurane Patent Dispute. - PR …  -  Sep 23, 2005
Baxter Prevails in Sevoflurane Patent Dispute. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

RxElite Announces Preferred Contract Status Awarded for Their …  -  Apr 10, 2008
Sevoflurane is the most commonly used anesthetic gas in the United States and Isoflurane continues to be used widely in anesthesia practice. ... marketwire.com

MINRAD International, Inc. Announces Construction Completion Of Phase...  -  Nov 6, 2007
The addition of the Sevoflurane API line will increase the capacity of ... Each step in the Sevoflurane production process is validated separately and the ... Medical News Today - Medical News Today (press release)

Baxter launches sevoflurane in China.(Baxter Healthcare Corp.)(Brief ...  -  Dec 19, 2005
Baxter Healthcare says it has launched sevoflurane, the world's most widely-used inhaled anesthetic, in China. The company also unveiled its plans for a ... $4.95 - Pharma Marketletter - ECNext

Doctor rebuked for theft of anesthetic  -  Aug 23, 2007
Several pharmacological Web sites list Sevoflurane as suitable for use in human and veterinary health care. Brodsky is one of 19 anesthesiologists with ... Cape Cod Times

Federal Register 2006 - 71 FR 8859 Request for Information on Waste …  -  Feb 21, 2006
Isoflurane, desflurane, and sevoflurane are commonly used for anesthesia in modern hospitals; however, no occupational exposure limits exist for these ... Pay-Per-View - Federal Register 2006 - Loislaw

… Artery Bypass Surgery; Sevoflurane preserved myocardial function...  -  Apr 23, 2005
2005 APR 23 - (NewsRx.com) -- Sevoflurane but not propofol preserves myocardial function ... Keywords: Kiel, Germany, Angiology, Sevoflurane, Propofol, ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… Artery Bypass Surgery; Sevoflurane preserved myocardial function...  -  Apr 19, 2005
2005 APR 19 - (NewsRx.com) -- Sevoflurane but not propofol preserves myocardial function ... Keywords: Kiel, Germany, Angiology, Sevoflurane, Propofol, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Article: Comparison of propofol and sevoflurane for laryngeal mask …  -  Apr 1, 2007
Comparison of propofol and sevoflurane for laryngeal mask airway insertion in elderly patients. ... find Southern Medical Journal articles. Pay-Per-View - Southern Medical Journal - HighBeam Research

… Schleswig Holstein, Kiel; Sevoflurane preserved myocardial...  -  Apr 20, 2005
2005 APR 20 - (NewsRx.com) -- Sevoflurane but not propofol preserves myocardial function ... Keywords: Kiel, Germany, Angiology, Sevoflurane, Propofol, ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

… , Inc. Announces Validation Completion of its New Sevoflurane API...  -  Dec 10, 2007
The addition of the Sevoflurane API line will increase the capacity of MINRAD's Bethlehem ... With validation of the new Sevoflurane API line complete, ... $4.95 - PR Newswire - ECNext

… Artery Bypass Surgery; Sevoflurane preserved myocardial function...  -  Apr 24, 2005
2005 APR 24 - (NewsRx.com) -- Sevoflurane but not propofol preserves myocardial function ... Keywords: Kiel, Germany, Angiology, Sevoflurane, Propofol, ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

… Japanese Approval of Sevoflurane. - PR Newswire | HighBeam  -  Mar 20, 2007
MINRAD International, Inc. Announces Japanese Approval of Sevoflurane. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… Artery Bypass Surgery; Sevoflurane preserved myocardial function...  -  Apr 22, 2005
2005 APR 22 - (NewsRx.com) -- Sevoflurane but not propofol preserves myocardial function ... Keywords: Kiel, Germany, Angiology, Sevoflurane, Propofol, ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Stocks to Follow and Alerts for Monday, Dec 12, 2005 SKPI ECPN and …  -  Dec 12, 2005
The company also unveiled its plans for a phased launch of sevoflurane in ... Baxter's sevoflurane is chemically and therapeutically equivalent to Ultane ... Free with registration - M2 Presswire - AccessMyLibrary.com

United States, Intellectual Property, Anticipation Does Not Require …  -  Jan 12, 2006
Abbott's patent solved the problem that sevoflurane was highly susceptible to Lewis acids degradation occurring during shipping and storage and claimed ... Mondaq News Alerts - Mondaq News Alerts (Registration)

… FDA Approval of Sojourn(TM) Sevoflurane. - PR Newswire | Hi  -  May 2, 2007
MINRAD International, Inc. Announces FDA Approval of Sojourn(TM) Sevoflurane. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

MINRAD's sevoflurane approved in Japan.  -  Mar 26, 2007
MINRAD's sevoflurane approved in Japan. Orchard Park, New York, USA-based pain management specialist MINRAD International says that its exclusive ... $9.94 - Pharma Marketletter - Alacra Store

Sevoflurane Vs Desflurane: Haemodynamic Parameters And Recovery …  -  Jan 1, 2005
Sevoflurane Vs Desflurane: Haemodynamic Parameters And Recovery Characteristics Sevoflurane Vs Desflurane: Haemodynamic Parameters And Recovery ... Subscription - Internet Journal of Anesthesiology - EBSCO Publishing

MINRAD's sevoflurane approved in Japan.(MINRAD International)(Merck …  -  Mar 26, 2007
Orchard Park, New York, USA-based pain management specialist MINRAD International says that its exclusive distribution partner in Japan, Merck Seiyaku, ... $4.95 - Pharma Marketletter - ECNext

Anticipation Does Not Require Appreciation.  -  Dec 1, 2006
Abbott's patent solved the problem that sevoflurane was highly susceptible to Lewis acids degradation occurring during shipping and storage and claimed ... $9.94 - Mondaq Business Briefing - Alacra Store

Amgen Buying Abgenix for $2.2B and MedImmune and Biota Announce …  -  Dec 15, 2005
Baxter has had FDA approval to sell its sevoflurane product since 2002, but Abbott has patents associated with its product that don't expire until 2017 and ... Free with registration - M2 Presswire - AccessMyLibrary.com

… International, Inc. Announces FDA Approval of Sojourn(TM) Sevoflura...  -  May 2, 2007
Inc. today announced it has received approval from the US Food and Drug Administration to market Sojourn(TM) (Sevoflurane) inhalation anesthetic. ... $4.95 - PR Newswire - ECNext

United States: Federal Circuit Rules En Banc on Intent Necessary to …  -  Jan 30, 2007
The composition of sevoflurane was well-known when Abbott shipped its ... However, due to degradation of Abbott's original sevoflurane product on the shelf, ... Mondaq News Alerts - Mondaq News Alerts (Registration)

Patent Dispute Ruling highlights Healthcare News-Update.  -  Sep 27, 2005
US District Court for the Northern District of Illinois Judge, Ronald Guzman, ruled that while Abbott's patent connected to sevoflurane combined with water ... $4.95 - M2 Presswire - ECNext

[U] Abbott Laboratories v. Baxter International, Inc., No. 06-3799...  -  Mar 5, 2007
The award is designed to keep Baxter out of the sevoflurane business during ... Customers shopping for sevoflurane during 2005 for delivery during 2006 were ... $2.95 - U.S. Court of Appeals, Seventh Circuit - VersusLaw

United States Federal Circuit Court of Appeals Reports - ABBOTT …  -  Jan 16, 2007
I. BACKGROUND A. The technology Sevoflurane is a fast-acting, ... However, pure sevoflurane has a serious problem, unknown at the time of its invention and ... Pay-Per-View - United States Federal Circuit Court of... - Loislaw

… FR 25507 Certain Other Dosage Form New Animal Drugs; Sevoflurane …  -  May 7, 2008
73 FR 25507 Certain Other Dosage Form New Animal Drugs; Sevoflurane 21 CFR Part 529 May 7, 2008 AGENCY: Food ... Sevoflurane liquid. (b) Sponsors. See Nos. ... Pay-Per-View - Federal Register 2008 - Loislaw

Angiotensin; Studies advance knowledge in angiotensin research  -  Oct 28, 2005
..."Sevoflurane dilates blood vessels and reduces arterial blood pressure in a ... "We designed this study to examine the effects of sevoflurane on Ang ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Angiotensin; Studies advance knowledge in angiotensin research  -  Oct 25, 2005
..."Sevoflurane dilates blood vessels and reduces arterial blood pressure in a ... "We designed this study to examine the effects of sevoflurane on Ang ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

How Depth of Anesthesia Influences the Blood Oxygenation Level– …  -  Sep 1, 2008
METHOD: We performed BOLD-based fMRI on a visual stimulus flickering at 8 Hz at sevoflurane concentrations of 0.5 minimum alveolar concentration (MAC), ... AJNR (subscription)

Press Release: MINRAD International, Inc. Announces Construction …  -  Nov 5, 2007
The addition of the Sevoflurane API line will increase the capacity of ... Each step in the Sevoflurane production process is validated separately and the ... Pay-Per-View - PR Newswire - HighBeam Research

Improving MRI Scan Quality in Paediatric Patients Undergoing …  -  Oct 22, 2007
Patients were initially induced with sevoflurane, and then randomised into one of ... The first group of 101 patients received an additional 2% sevoflurane ... DG News

How Depth of Anesthesia Influences the Blood Oxygenation Level– …  -  Jun 8, 2005
At a concentration of 0.5 MAC, the anesthetic agent sevoflurane has been shown to have no significant influence on the BOLD signal intensity amplitude of ... AJNR (subscription)

Buffalo News, The : Minrad reports $11.7 million loss  -  Aug 16, 2008
...sevoflurane anesthetic line for scheduled cleaning and maintenance and delays ... It also endured an equipment breakdown in a sevoflurane reactor, a ... $2.95 - Buffalo News - NewsBank

Baxter Widens Anesthetic Plan  -  Jan 4, 2006
Baxter announced in mid-December the launch of sevoflurane in China and is looking ... Baxter estimates $800 million in global annual sales for sevoflurane, ... Subscription - Wall Street Journal Online - Dow Jones & Company

Press Release: MINRAD International, Inc. Announces Q2 2007 Financial...  -  Aug 14, 2007
This increase is primarily attributed to the ability to sell sevoflurane in ... The potential revenue from additional sevoflurane sales was reduced by the ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: MINRAD International, Inc. Announces 2007 Financial …  -  Mar 31, 2008
Sevoflurane sales in 2007 were $8378, a decrease of $2160 compared to 2006. Isoflurane sales in 2007 were $3211, a decrease of $1068 when compared to 2006. ... Pay-Per-View - PR Newswire - HighBeam Research

MINRAD International, Inc. Announces Q2 2007 Financial Results  -  Aug 14, 2007
This increase is primarily attributed to the ability to sell sevoflurane in ... The potential revenue from additional sevoflurane sales was reduced by the ... Genetic Engineering News - Genetic Engineering News (press release)

Chem Lab: Medical Assistant Drops Dead While Huffing Ether in...  -  Nov 8, 2007
In conclusion, we report a case of self-inflicted death from sevoflurane ... The novel findings in the present report include sevoflurane as the sole cause ... Wired News

Anesthesia; Recovery of morbidly obese surgical patients better with ...  -  Feb 14, 2005
..."We compared postoperative recovery after desflurane (n=25) versus sevoflurane (n=25) anesthesia in morbidly obese adults (body mass index 35) who underwent ... Pay-Per-View - Pain & Central Nervous System Week - Factiva, from Dow Jones

University of Southern California; Recovery of morbidly obese...  -  Feb 16, 2005
..."We compared postoperative recovery after desflurane (n=25) versus sevoflurane (n=25) anesthesia in morbidly obese adults (body mass index 35) who underwent ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Anesthesia; Recovery of morbidly obese surgical patients better with ...  -  Feb 19, 2005
..."We compared postoperative recovery after desflurane (n=25) versus sevoflurane (n=25) anesthesia in morbidly obese adults (body mass index 35) who underwent ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Anesthesia; Recovery of morbidly obese surgical patients better with ...  -  Feb 20, 2005
..."We compared postoperative recovery after desflurane (n=25) versus sevoflurane (n=25) anesthesia in morbidly obese adults (body mass index 35) who underwent ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Anesthesia; Recovery of morbidly obese surgical patients better with ...  -  Feb 14, 2005
..."We compared postoperative recovery after desflurane (n=25) versus sevoflurane (n=25) anesthesia in morbidly obese adults (body mass index 35) who underwent ... Pay-Per-View - Clinical Trials Week - Factiva, from Dow Jones

Does anaesthesia make pain worse?  -  Jul 8, 2008
Non-pungent volatile general anaesthetics, such as sevoflurane, did not activate the TRPA1 channel. When nerve cells from normal mice were exposed to ... Scotsman

Economic and safety considerations of fast-acting inhaled anesthetics....  -  Oct 1, 2007
Summarize the potential for degradation of sevoflurane by Lewis acids ... The currently available inhalational anesthetics, sevoflurane, isoflurane, ... $4.95 - Formulary - ECNext

Event Brief of Q4 2005 BAXTER INTL INC Earnings Conference Call - …  -  Jan 26, 2006
Launched Sevoflurane, and recently launched product in Japan. 1. Plan launches for Sevoflurane in US in 1Q and phase launches in Europe throughout rest of ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Obstetric Anesthesia; Drug interaction effect on contractile activity...  -  Feb 1, 2005
Measurements showed "sevoflurane (0.5 to 3 MAC) inhibited the amplitude and ... Sevoflurane responses were repeated in the presence of isradipine (a ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Press Release: MINRAD International, Inc. Announces Q3 2007 Financial...  -  Nov 13, 2007
This decrease is primarily attributed to the reduction in Sevoflurane sales in the ... We believe the addition of our Sevoflurane API Line will allow us to ... Pay-Per-View - PR Newswire - HighBeam Research

Obstetric Anesthesia; Drug interaction effect on contractile activity...  -  Feb 4, 2005
Measurements showed "sevoflurane (0.5 to 3 MAC) inhibited the amplitude and ... Sevoflurane responses were repeated in the presence of isradipine (a ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

MINRAD International, Inc. Announces Construction Completion of Phase...  -  Nov 5, 2007
The addition of the Sevoflurane API line will increase the capacity of ... Each step in the Sevoflurane production process is validated separately and the ... $4.95 - PR Newswire - ECNext

Loislaw Federal District Court Opinions - ABBOTT LABORATORIES v. …  -  Sep 22, 2005
...fn1] Water is used in the production of sevoflurane, and so there is ... In fact, because sevoflurane naturally absorbs water and there is always some ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Loislaw Federal District Court Opinions - ABBOTT LABORATORIES v. …  -  Sep 26, 2005
...fn1] Water is used in the production of sevoflurane, and so there is ... In fact, because sevoflurane naturally absorbs water and there is always some ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Anesthesia-related hypotension in a small-animal practice: this …  -  Jan 1, 2006
Vaporizer settings during maintenance were 1.5% to 2% for isoflurane and 2% to 3% for sevoflurane. Oxygen flow rates were 800 ml/min for animals less than ... Free with registration - Veterinary Medicine - AccessMyLibrary.com

Painkillers' Surprising Legacy Is More Pain  -  Jun 23, 2008
...mustard oil to the ears of mice, a commonly used model of neurogenic inflammation, and then anesthetized them with either isoflurane or sevoflurane. ... MedPage Today

MINRAD International, Inc. Announces Q1 2007 Financial Results.  -  May 15, 2007
This decrease is primarily attributed to the processing of both isoflurane and sevoflurane on our isoflurane active pharmaceutical production line to meet ... Free with registration - PR Newswire - AccessMyLibrary.com

Minrad International, Inc. Announces Results for Three Months Ended …  -  Mar 17, 2005
..."The launch of sevoflurane is a crucial component in the growth of our anesthesia and ... "While the preparation of validation batches of sevoflurane caused ... Free with registration - PR Newswire - AccessMyLibrary.com

Minrad cuts loss as its sales surge  -  May 14, 2008
The company has received approval to sell its sevoflurane product in 18 countries and is currently selling it in 13 of them, Burns said. ... $2.95 - Buffalo News - NewsBank

Baxter moves ahead with drug despite fight  -  Jan 2, 2006
In September, a US District Court judge ruled Baxter's sevoflurane doesn't ... Inhaled anesthetic agents like sevoflurane are administered to patients ... $2.95 - Chicago Sun-Times - NewsBank

Anesthesiology; More evidence for drug-specificity of bispectral...  -  Feb 19, 2005
..."BIS values in awake patients did not differ between the sevoflurane and halothane groups (96±2 and 96±2, mean±SD, respectively)," published data showed. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Anesthesiology; More evidence for drug-specificity of bispectral...  -  Feb 14, 2005
..."BIS values in awake patients did not differ between the sevoflurane and halothane groups (96±2 and 96±2, mean±SD, respectively)," published data showed. ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

University Hospital, Basel; More evidence for drug-specificity of...  -  Feb 16, 2005
..."BIS values in awake patients did not differ between the sevoflurane and halothane groups (96±2 and 96±2, mean±SD, respectively)," published data showed. ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Press Release: Minrad International, Inc. Announces Results for Three...  -  Mar 17, 2005
..."The launch of sevoflurane is a crucial component in the growth of our anesthesia and ... "While the preparation of validation batches of sevoflurane caused ... Pay-Per-View - PR Newswire - HighBeam Research

Loislaw Federal District Court Opinions - LABORATORIES v. BAXTER …  -  Sep 28, 2007
Sevoflurane, which is found in Abbott's Ultane TM product, is used to induce and maintain general anesthesia in adult and pediatric Page 2 patients. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

MINRAD International, Inc. Announces Fourth Quarter 2006 Financial …  -  Mar 30, 2007
The primary increase in sales was due the increase of sales of sevoflurane. In the fourth quarter of 2006, sales of sevoflurane comprised approximately 72% ... Genetic Engineering News - Genetic Engineering News (press release)

Neuromuscular Blocking Agents May Affect Bispectral and Auditory …  -  Oct 31, 2005
In the study, 20 patients were given sevoflurane for 30 minutes to a BIS of 50 (baseline) and were randomized to receive a rocuronium infusion maintained ... DG News

Event Brief of Q1 2006 Baxter International Inc. Earnings Conference...  -  Apr 20, 2006
Medication Delivery business launched Sevoflurane, the world's most widely ... With the addition of Sevoflurane, BAX is now the only Co. to offer all three ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Piramal Healthcare Limited to Acquire Minrad International, Inc.  -  Dec 22, 2008
...including process-based intellectual property for both sevoflurane and ... market for sevoflurane, the largest selling inhalation anesthetic in the US. ... RedOrbit

Is IV access necessary for myringotomy with tubes?(intravenous)(Clinic...  -  Nov 1, 2007
Two available inhaled anesthetics are halothane and sevoflurane. Sevoflurane has gained popularity because it has been shown to allow faster induction and ... $4.95 - Ear, Nose and Throat Journal - ECNext

Anesthesia; Auditory evoked potentials and EEG analysis accurately …  -  Dec 27, 2005
..."Sevoflurane or propofol was given until loss of consciousness," the scientists ... "After intubation, propofol or sevoflurane was stopped until patients ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

MINRAD International, Inc. (AMEX: BUF) enters new markets  -  Jun 17, 2008
Sevoflurane has already been in the US drug market since May 2007 and has greatly ... Although sales of Sevoflurane really added to MINRAD's revenues, ... HotStocked

Novel Radiator for Carbon Dioxide Absorbents in Low-Flow Anesthesia  -  Oct 1, 2006
During long-term low-flow sevoflurane anesthesia, dew formation and the generation of ... Anesthesia was maintained with N 2 O, O 2 , and sevoflurane, ... Annals of Clinical & Laboratory Science...

Article: The facts about epilepsy.(News) - Birmingham Mail (England)...  -  Nov 12, 2005
Convulsive movements with sevoflurane The letter from Dr Zacharias regarding convulsive movements with sevoflurane induction in children . ... Pay-Per-View - Birmingham Mail - HighBeam Research

Boeing, Union Reach Pact  -  Sep 26, 2005
Baxter International (BAX ) A US District Court judge ruled that Abbott Laboratories' patent related to sevoflurane combined with water was not infringed by ... BusinessWeek

The role of anaesthesia in MRI procedures  -  Mar 8, 2007
...'For these we begin with Sevoflurane during induction and move on to intravenous or balanced ... For the recovery phase we prefer Sevoflurane anaesthesia. ... European Hospital

American Ecology trading on Nasdaq Global Select  -  Jul 24, 2007
Minrad's version of generic Sevoflurane received FDA approval on May 2. "Becoming a public company allows RxElite to enjoy broader exposure to the ... $2.95 - Idaho Statesman - NewsBank

Press Release: MINRAD Announces Three Regulatory Approvals. - PR …  -  Jul 28, 2008
Sevoflurane Shelf Life Extension. MINRAD also announces completion of 3-year ... Currently, the company has marketing authorization for Sevoflurane in 17 ... Pay-Per-View - PR Newswire - HighBeam Research

Brand Names/Synonyms:
Sevoflurane is also known by the following brand names and/or synonymsBax 3084; CHEMBANK2842; MR6S4; Sevofluran; Sevoflurane; Sevoflurane [Usan:Ban:Inn:Jan]; Sevoflurano [Inn-Spanish]; Sevofluranum [Inn-Latin]; Sevorane; Ultane; [Inn-Latin]

Drug Category:
Sevoflurane is categorized under the following by the FDA: Anesthetics; General Anesthetics; ATC:N01AB08

Dosage Forms:
LIQUID

Absorption:
Rapidly absorbed into the circulation via the lungs

Interactions:
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Chemical IUPAC Name:
1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane





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