Silvadene

This page contains recent news articles, when available, and an overview of Silvadene but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Silvadene
(when available)

Pharmacology and use:
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus. For the treatment of rheumatic fever and meningococcal meningitis

Mechanism Of Action:
Sulfadiazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.

News Articles on Sulfadiazine

Silvadene Cream 1%.(Drug overview)  -  Jan 22, 2007
Silvadene Cream 1% is applied directly to the skin. The cream is used along with other medications to prevent and treat wound infections in people with ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

CLINICAL PEARL- SILVADENE CREAM FOR SUNBURN  -  Apr 21, 2007
For severe sunburn, especially with blistering, have patients apply 1% silver sulfadiazine (Silvadene Cream) bid (including after showering). ... Clinical Advisor

There is a balm in Charlottesville / U.Va. doctors treat wounds and...  -  Apr 4, 2007
At U.Va., Rodeheaver's gel has taken the place of popular antibacterial creams such as Silvadene. Because Pluronic is water- soluble, it washes out of ... Pay-Per-View - Richmond Times - Dispatch - ProQuest Archiver

Loislaw Federal District Court Opinions - LEDUC v. COMMISSIONER OF …  -  Aug 12, 2008
Id. Dr. Kennedy prescribed the Silvadene and Darvocet at the end of this visit. ... LeDuc was told to continue with the Silvadene cream per Dr. Kennedy's ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Louisiana Case Law - TIPTON v. CAMPBELL, 2008-0139 (La.App. 4 Cir. …  -  Sep 24, 2008
He prescribed Silvadene cream for her eschar and prophylactic antibiotics. ... He continued her on the antibiotics and the Silvadene cream for the eschar. ... Pay-Per-View - Louisiana Case Law - Loislaw

Loislaw Federal District Court Opinions - MORRIS v. METROPOLITAN …  -  May 24, 2005
She applied Silvadene cream and saw Dr. Hassett four days later. ... Dr. Ernsting again prescribed Silvadene cream. Admin. R. 163. 2. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Cutting-edge wound technology: advanced technology in silver dressings...  -  Mar 1, 2007
A cost analysis done in 2005 of Silvadene, an older treatment method, ... The study discovered that the average cost for a traditional Silvadene dressing ... Free with registration - Nursing Homes - AccessMyLibrary.com

Burn after reading, not  -  Oct 26, 2008
After debridement, an antimicrobial ointment, usually Silvadene (silver ... Silvadene should also be avoided in children allergic to sulfa drugs,� said Dr. ... Malaysia Star

Do topical antibiotics improve wound healing?(CLINICAL INQUIRIES: …  -  Feb 1, 2007
Topical preparations that may be helpful include dimethyl sulfoxide (Rimso-50), silver sulfadiazine (Silvadene), benzoyl peroxide (Benzac, Brevoxyl, ... $4.95 - Journal of Family Practice - ECNext

Article: Mafenide tied to fungal infections in burn patients.(Wound...  -  Jul 1, 2008
PR Newswire; May 15, 2006 ; 700+ words ... ... to a protocol of care including silver sulfadiazine (silvadene) cream, according ... procedural medications ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Loislaw Federal District Court Opinions - WALKER v. REESE (SDMiss. 8-...  -  Aug 13, 2008
He was given medication (Silvadene creme and Percocet) and directed to follow up with a burn surgeon. When plaintiff returned to FCC Yazoo City, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

New York Miscellaneous Reports - ASSAF v. NEW YORK & PRESBYT. …  -  Mar 16, 2007
After that, Dr. Greenberg opines that treatment for this condition was appropriate, with the use of Bacitracin ointment on the 23rd followed by Silvadene ... Pay-Per-View - New York Miscellaneous Reports - Loislaw

Press Release: Derma Sciences MEDIHONEY(TM) Featured in CBS …  -  Aug 4, 2008
Additionally, the Iraqi families preferred MEDIHONEY over silvadene -- considered standard of care -- because it was natural and does not need to be changed ... Pay-Per-View - PR Newswire - HighBeam Research

Silver-coated dressing market booms as manufacturers 'jump on …  -  Aug 1, 2007
..."Physicians used to use a product called Silvadene [a silver-based cream] for years," says Nancy Morgan, RN, BSN, MBA, ET, CWCN, WCC, cofounder and clinical ... $4.95 - Hospital Materials Management - ECNext

Safe biking tips for summer.(Your Life)  -  Jul 1, 2005
..."After cleansing, the affected area should be covered with a dressing and a topical antibiotic such as bacitracin, polysporin, or silvadene, which help ... $4.95 - USA Today (Magazine) - ECNext

Article: You can offer balm to the badly burned kids of Iraq.(NEWS)(Do...  -  Nov 5, 2006
PR Newswire; August 4, 2008 ; 700+ words ... ... silvadene antimicrobial cream at the Smith Gate Burn Clinic, the only service in Iraq ... stated, ... Pay-Per-View - Star Tribune - HighBeam Research

Rivera v. Rees, No. 1:05-CV-00038-REC-LJO-P (EDCal. 02/22/2006)  -  Feb 22, 2006
On October 14, 2003, Plaintiff was prescribed Silvadene cream to apply to the rash, and Tylenol for thirty days. In addition, Plaintiff was medically ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

House Calls ; There is no single treatment that works for every...  -  Oct 9, 2005
There are a variety of antibiotic ointments; creams, such as Silvadene; solutions; and dressings, such as silver-impregnated gauze and hydrogel. ... Pay-Per-View - Orlando Sentinel - ProQuest Archiver

Co-worker in blast had no inkling of suicide  -  Dec 2, 2006
He must cover his hands and stomach daily with Silvadene, a topical cream used to prevent and treat skin infections on areas of burned skin, ... Youngstown Vindicator

30 minutes to a better mood  -  Nov 4, 2008
She may want to treat it with an antibiotic cream called Silvadene that kills bacteria and keeps the burn moist. DRINK THIS, DROP POUNDS: Sipping green tea ... Toronto Star

They Can Be Painful, Unsightly, Or Both -- But An Expert Explained...  -  Mar 5, 2008
Then, use a healing ointment with silver, such as Silvadene. If you can't get your hands on it, aloe is still useful. Cover from the sun, so it doesn't ... CBS News

UT Southwestern sports medicine doctor pedals advice on gearing up...  -  Apr 21, 2005
..."After cleansing, the affected area should be covered with a dressing and a topical antibiotic such as bacitracin, polysporin or silvadene, which help ... eurekalert.org

Oral Agreement  -  May 25, 2006
Management is with topical antibiotics such as Silvadene. Also, when the lips are in the treatment field, they are vulnerable. Aquaphor is useful to prevent ... Dental Economics

Martin v. Crall, No. 3:05CV-P399-H (WDKy. 03/08/2007)  -  Mar 8, 2007
...underwent laboratory testing; and was prescribed Cipro and Diflucan, Mycolog and Silvadene creams, foot soaks with antimicrobial soaps and brush, ... $2.95 - U.S. District Court, Western District... - VersusLaw

Sports medicine doctor pedals advice on gearing up for safe cycling …  -  Apr 22, 2005
..."After cleansing, the affected area should be covered with a dressing and a topical antibiotic such as bacitracin, polysporin or silvadene, which help ... Medical News Today - Medical News Today (press release)

AQUACEL(R) Ag Hydrofiber(R) Dressing Demonstrated Benefits Over …  -  May 16, 2006
...management of adult and pediatric patients with partial thickness burns compared to a protocol of care including silver sulfadiazine (silvadene) cream, ... Medical News Today - Medical News Today (press release)

THE YOU DOCS.(Life and Arts) | Article from Seattle Post-Intelligencer...  -  Nov 5, 2008
He or she may want to treat it with an antibiotic cream called Silvadene that kills bacteria and keeps the burn moist. TO SUBMIT QUESTIONS TO Mike Roizen ... Pay-Per-View - Seattle Post-Intelligencer - HighBeam Research

Highlights of the American Academy of Emergency Medicine (AAEM): …  -  Feb 16, 2006
Silver sulfadiazine (Silvadene) cream or mafenide acetate (Sulfamylon) cream should be applied as a thick layer as opposed to a lotion. ... Medscape

Physician Pedals Advice on Gearing Up for Safe Cycling Season  -  May 17, 2005
..."After cleansing, the affected area should be covered with a dressing and a topical antibiotic such as bacitracin, polysporin or silvadene, which help ... newswise.com

News Briefs  -  Jan 11, 2005
...fungal creams, oral diabetes and hypertension medications, bandages, over-the-counter vitamins, aspirin, ibuprofen, and Silvadene burn cream. ... Gateway

Sports Medicine Doctor Pedals Advice on Gearing Up for Safe Cycling …  -  Apr 27, 2005
...“After cleansing, the affected area should be covered with a dressing and a topical antibiotic such as bacitracin, polysporin or silvadene, which help ... DentalPlans.com

emulsion | Definition of emulsion | HighBeam.com: Online Dictionary  -  Jul 12, 2006
Burns are less likely to become infected when they are treated with the silver compound silvadene. Russell Fields is president of the Nevada Mining ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Few pediatric palm burns need surgery.(Clinical Rounds)(Brief...  -  Aug 1, 2007
The management plan includes in-hospital wound debridement, parents' doing daffy dressing changes with Silvadene, and pain control. ... Free with registration - Pediatric News - AccessMyLibrary.com

Emu Oil: an Interview with Paul Pluss of Jurassic Secret Emu Oil...  -  Jul 1, 2005
Studies so far say that it is superior to Silvadene and other standard burn treatments. Burn centers are sometimes reluctant to use it because it is not ... Natural News.com

Get burned? Do the right thing - The You Docs Tip of the Day:  -  Nov 5, 2008
She may want to treat it with an antibiotic cream called Silvadene that kills bacteria and keeps the burn moist. The You Docs - Mike Roizen and Mehmet Oz ... $2.95 - Idaho Statesman - NewsBank

Ohio Appellate Reports - McMANAWAY v. FAIRFIELD MED. CTR., …  -  Apr 7, 2006
Upon discharge from the hospital, Appellee McManaway was provided Silvadene topical cream for the burns. {¶ 4} The next day, a public relations employee of ... Pay-Per-View - Ohio Appellate Reports - Loislaw

No surgery required for most pediatric palm burns.(Clinical Rounds)  -  Jun 1, 2007
The management plan includes inhospital wound debridement, parents" doing daily dressing changes with Silvadene, and pain control. ... Free with registration - Skin & Allergy News - AccessMyLibrary.com

Ophthalmology for Equine Road Warriors  -  Mar 11, 2005
For example, she said that the Silvadene (silver sulfadiazine) label says not to use it in eyes, which can be very alarming to the client, ... TheHorse.com

Journal of Burn Care & Research Reports AQUACEL(R) Ag Hydrofiber(R) …  -  May 15, 2006
...management of adult and pediatric patients with partial thickness burns compared to a protocol of care including silver sulfadiazine (silvadene) cream, ... $4.95 - PR Newswire - ECNext

Epidermolysis bullosa: management principles for the neonate, infant,...  -  Feb 1, 2005
Removal of punctured dressings in bath tub. blisters * Apply antibiotic ointment (eg, Bactroban[R], Silvadene[R],) to clean wound followed by Vaseline', ... Free with registration - Dermatology Nursing - AccessMyLibrary.com

The You Docs tips for the week  -  Nov 8, 2008
She may want to treat it with an antibiotic cream called Silvadene that kills bacteria and keeps the burn moist. Make an extra stop on your way home today. ... Telegraph-Journal

Loislaw Federal District Court Opinions - NIXON v. PENNER (EDCal. 8...  -  Aug 16, 2006
Also, plaintiff was provided Betadine soaks and silvadene ointment as topical antibiotic. (Penner Decl. at 2.) By the end of August 2002, plaintiff's fungal ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Sea Turtle Hospital News  -  Apr 30, 2008
For most of the external injuries we use lots of Betadine, Silvadene (SSD) and triple antibiotic ointment. To treat pain, infections and pneumonia we use ... Topsail Advertiser - The Topsail Advertiser

New York Codes, Rules and Regulations - APPENDIX 17-D  -  May 18, 2007
Protopam) Ethyl Chloride spray Silver Nitrate sticks Gelfoam Silver Sulfadiazine cream (eg, Silvadene) Glycerin suppository Sodium Chloride — injection ... Pay-Per-View - New York Codes, Rules and Regulations - Loislaw

Loislaw Federal District Court Opinions - US v. AKERS (NDWVa. 2005)  -  Sep 21, 2005
7) Defendant is prescribed nitroglycerin, Advair, Combivent, OxyContin, Percocet, and Silvadene. 8) Defendant presents a risk of continuing to engage in ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

New York Codes, Rules and Regulations - APPENDIX C-6  -  May 18, 2007
Pralidoxime Chloride (e.g. Protopam) Ethyl Chloride spray Silver Nitrate Sticks Gelfoam Silver Sulfadiazine cream (e.g. Silvadene) Glycerin suppository ... Pay-Per-View - New York Codes, Rules and Regulations - Loislaw

The acanthocladous syndrome.(Short story)  -  Oct 1, 2005
And that Dermatologist telling him to change my bath soap, and prescribing Silvadene! "And he used them, used them as directed, too. ... $4.95 - Journal of Evolutionary Psychology - ECNext

Article: Exploring alternate media avenues: outdoor and place-based …  -  Jan 1, 2007
AVC, a vaginal anti-infective cream; and Silvadene, a burn cream. Altace is the largest of the acquisitions, having produced 1997 sales of ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

HOT-FOOTED KIDS | Article from Parenting | HighBeam Research  -  Aug 1, 2008
If the blisters are closed, smooth on a thin layer of a burn cream like Silvadene twice daily, and bandage. 3. When the blisters open, ... Pay-Per-View - Parenting - HighBeam Research

Loislaw Federal District Court Opinions - WALKER v. REESE (SDMiss. 9-...  -  Sep 25, 2008
His discharge instructions were to treat the wounds daily with Silvadene creme. He also was prescribed various pain medications. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Reflections on Haiti: love, warmth, and milk.(Inspirations) | Article...  -  Jul 1, 2005
Although we could give her silvadene cream and dressing supplies, there is no access to sunscreen even if it were affordable, nor is there an understanding ... Pay-Per-View - Pediatric Nursing - HighBeam Research

Myth Buster | Article from Parenting | HighBeam Research  -  Sep 1, 2007
If the blisters are closed, smooth on a thin layer of a burn cream like Silvadene twice daily, and bandage. 3. When the blisters open, ... Pay-Per-View - Parenting - HighBeam Research

[U] Loehr v. Barnhart, No. C05-3025-MWB (NDIowa 04/20/2006)  -  Apr 20, 2006
The wounds were cleaned, debrided, and re-dressed, and he was given a prescription for Silvadene cream and Darvocet. He was told to change his dressing ... $2.95 - U.S. District Court, Northern District... - VersusLaw

Safety Gear Checklist | Article from Motor Boating | HighBeam Research  -  Apr 1, 2008
...two-person survival blankets; bailer, bucket, sponge; large pressure dressings and gauze for serious bleeding; Silvadene for burns; seasick medication; ... Pay-Per-View - Motor Boating - HighBeam Research

Reflections on Haiti: love, warmth, and milk.(Inspirations)  -  Jul 1, 2005
Although we could give her silvadene cream and dressing supplies, there is no access to sunscreen even if it were affordable, nor is there an understanding ... $4.95 - Pediatric Nursing - ECNext

Kealoha v. Dep't of Public Safety of the State of Hawaii, No. 05...  -  May 2, 2007
Kealoha was treated with antibiotics and Silvadene. [52], 42. At the time of trial in April 2007, the burn scar on Kealoha's right upper arm covered a large ... $2.95 - U.S. District Court, District of Hawaii - VersusLaw

Arthritis drug on agenda.(RX RETAIL PHARMACY: Government)(Brief …  -  Jun 30, 2008
Chain Drug Review; October 23, 1989 ; 700+ words ... ... delivery system for its popular Silvadene wound ointment and an artificial skin known as Integra. ... Pay-Per-View - Chain Drug Review - HighBeam Research

Loislaw Federal District Court Opinions - CANNADAY v. ASTRUE (WDVa. …  -  Jun 5, 2008
Cannaday was prescribed Cephalexin and was instructed to continue cleansing at home and to apply Silvadene cream and a light gauze dressing. (R. at 608. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Brand Names/Synonyms:
Silvadene is also known by the following brand names and/or synonymsA-306; Adiazin; Adiazine; Coco-Diazine; Cocodiazine; Codiazine; Cremodiazine; Cremotres; Debenal; Deltazina; Diazin; Diazolone; Diazovit; Diazyl; Eskadiazine; Honey Diazine; Lantrisul; Lipo-Diazine; Lipo-Levazine; Liquadiazine; Metha-Meridiazine; Microsulfon; Neazine; Neotrizine; Palatrize; Pecta-Diazine, Suspension; Piridisir; Pirimal; Pyrimal; Quadetts; Quadramoid; RP 2616; S. N. 112; SDA; Sanodiazine; Sildaflo; Silvadene; Spofadrizine; Ssd; Sterazine; Sulfa-Triple #2; Sulfacombin; Sulfadiazene; Sulfadiazin; Sulfadiazine; Sulfaloid; Sulfanilamidopyrimidine; Sulfapirimidin; Sulfapyrimidin; Sulfapyrimidine; Sulfatryl; Sulfazin; Sulfazine; Sulfolex; Sulfonamides Duplex; Sulfonsol; Sulfose; Sulphadiazine; Terfonyl; Theradiazine; Thermazene; Tri-Sulfameth; Trifonamide; Triple Sulfa; Triple Sulfas; Triple Sulfoid; Trisem; Trisulfapyrimidine, Oral Suspension; Truozine

Drug Category:
Silvadene is categorized under the following by the FDA: Antiprotozoals; Anti-Infectives; Anti-Infectives; ATC:D06BA01; ATC:J01EC02

Dosage Forms:
CREAM

Absorption:
Not Available

Interactions:
Not Available



Chemical IUPAC Name:
4-amino-N-pyrimidin-2-yl-benzenesulfonamide





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