Streptomycin Sulfate

This page contains recent news articles, when available, and an overview of Streptomycin Sulfate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Streptomycin Sulfate
(when available)

Pharmacology and use:
Streptomycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses. For the treatment of Tuberculosis

Mechanism Of Action:
Aminoglycosides like Streptomycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically Streptomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes.

News Articles on Streptomycin

… Code of Federal Regulations - 21 CFR § 520.2158a Streptomycin...  -  Jul 11, 2006
21 CFR § 520.2158a Streptomycin sulfate oral solution. (a) Specifications. Solution containing 25 percent streptomycin sulfate. (b) Sponsor. See Nos. ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

… Code - 77 Ill. Adm. Code 790.8340 STREPTOMYCIN SULFATE ( …  -  Aug 10, 2005
77 Ill. Adm. Code 790.8340 STREPTOMYCIN SULFATE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

Federal Register 2006 - 71 FR 17701 New Animal Drugs; Change of …  -  Apr 7, 2006
71 FR 17701 New Animal Drugs; Change of Sponsor; Soluble Bacitracin Methylene Disalicylate and Streptomycin Sulfate Oral Powder 21 CFR Parts 510 and 520 ... Pay-Per-View - Federal Register 2006 - Loislaw

Export price of antibiotic edges up in H1  -  Jul 10, 2007
INTERFAX-CHINA - The export price of streptomycin sulfate increased slightly in the first half of 2007, a pharmaceutical analyst said today. ... Free with registration - China Business News - AccessMyLibrary.com

Scale-Up Considerations for a Hollow-Fiber-Membrane Bioreactor …  -  Oct 12, 2005
Streptomycin sulfate, nalidixic acid, and cyclohexamide (Sigma Chemical Co., St. Louis, Missouri) were added to minimize contaminating organisms. ... RedOrbit

United States Code of Federal Regulations - 21 CFR § 520.154b …  -  Jul 11, 2006
21 CFR § 520.154b Bacitracin methylene disalicylate and streptomycin sulfate powder. (a) Specifications. Each gram of powder contains 200 units bacitracin ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

Federal Register 2008 - 73 FR 75105 Notice of Receipt of Requests to ...  -  Dec 10, 2008
Thidiazuron 50W Thidiazuron 067760 OR-00-0016 Fyfanon ULV Malathion 069678-00001 Streptomycin Sulfate Streptomycin sulfate Technical 069874-00002 Sodium ... Pay-Per-View - Federal Register 2008 - Loislaw

Apocynin derivatives interrupt intracellular signaling resulting in …  -  Jan 1, 2006
Tissue culture media (DMEM, RPMI) and penicillin G-streptomycin sulfate (GPS) were purchased from Mediatech (Cellgro, Va). Fetal bovine serum (FBS) was ... Free with registration - Journal of Biomedicine and Biotechnology - AccessMyLibrary.com

Why are my Bradford pear leaves turning brown?  -  Oct 15, 2007
Streptomycin sulfate, which is an antibiotic, a bordeaux mix or copper fungicide can be applied according to package instructions when the tree is in bloom. ... Houston Chronicle

Fireman's cap lures small birds  -  Aug 9, 2007
Streptomycin sulfate, an antibiotic; copper fungicide; or a bordeaux mix can be applied according to package instructions during the bloom stage. ... Houston Chronicle

Why are our Bradford pears ailing?  -  Oct 14, 2007
Streptomycin sulfate, an antibiotic; copper fungicide; or a bordeaux mix can be applied according to instructions during the bloom stage. ... Houston Chronicle

WHO expert committee on specifications for pharmaceutical preparations...  -  Aug 1, 2005
193176 9930416 streptomycin sulfate 100mg 197215 9930417 sulfacetamide 100mg 196200 9930419 sulfamethoxazole 100mg 179092 9930420 sulfamethoxypyridazine ... Free with registration - Technical Report Series - AccessMyLibrary.com

Gene profiling study of G3139- and Bcl-2-targeting siRNAs identifies...  -  Sep 30, 2005
25 mM HEPES, 100 U/ml penicillin G sodium and 100 g/ml streptomycin sulfate. Stock cultures were maintained at 37°C in a humidified 5% CO 2 incubator. ... Nature.com

USE OILS RIGHT, AND SPARINGLY, TO CONTROL BUGS  -  Mar 9, 2008
We got the trees looking healthy after much pruning but I was told to spray them to with a product called streptomycin sulfate. I do not know when to spray. ... Pay-Per-View - Daily Press - ProQuest Archiver

Apple trees' fire blight can cut output, kill  -  Jun 30, 2007
...the only preventive treatment for this disease is to spray the tree with streptomycin sulfate just before the blooms open in the spring. ... Pay-Per-View - Richmond Times - Dispatch - ProQuest Archiver

Leaf gall ugly, but won't hurt camellia  -  May 3, 2008
Commercial apple or pear producers often spray with streptomycin sulfate during bloom as a control, however most orchardists grow fireblight resistant ... Salisbury Post

PRUNTY: Diseases attack many plants during the summer .  -  Jul 1, 2005
Streptomycin sulfate, an antibiotic, is used hi commercial .orchards to prevent infection during bloom tune. Timing of the chemical is critical and based on ... Free-Lance Star - Google News Archive

… : soluble bacitracin methylene disalicylate and streptomycin...  -  Apr 7, 2006
...drug application (NADA) for bacitracin methylene disalicylate and streptomycin sulfate oral powder from Veterinary Specialties Inc to Alpharma Inc. This ... Pay-Per-View - Federal Register - Factiva, from Dow Jones

Pragmatic materials.  -  Aug 1, 2005
The products cited were NADH (nicotinamide-adenine dinucleotide, reduced sodium salt), oxytocin, streptomycin sulfate USP, polymyxin B sulfate, ... $9.94 - Pharmaceutical Technology - Alacra Store

Arkansas Regulations - 124.180 Tuberculosis (TB)  -  Apr 2, 2008
...mg tablets Rifampin/300 mg capsules Levofloxacin/250 mg tablets Isoniazid/Rifampin 150/300 mg capsules Levofloxacin/500 mg tablets Streptomycin Sulfate, ... Pay-Per-View - Arkansas Regulations - Loislaw

Role of interleukin-18 in modulation of oral carcinoma cell proliferat...  -  Jan 1, 2006
Germany) and antibiotics (100 unit/mL of penicillin G and 100 [micro]g/mL of streptomycin sulfate) and cultured at 37[degrees]C in 5% C[O.sub.2]. ... Free with registration - Mediators of Inflammation - AccessMyLibrary.com

Fire blight, scourge of the rose family, burns its way through Crook...  -  Jul 19, 2007
Bordeaux solution or some other copper-based fungicide or a spray containing streptomycin sulfate are also -used to medicate infected trees. ... Sundance Times - Google News Archive

The Daily News  -  Mar 2, 2005
Use streptomycin sulfate, Bordeaux mixture or Kocide during bloom (follow the manufacturer's directions). Prune out all infected wood using sharp shears ... Daily News - Galveston County

Fire Blight a problem this spring  -  May 18, 2006
A preventative spray with a material called streptomycin sulfate can be applied in early spring when about of the blooms are open on the tree. ... Jones County News - Google News Archive

Granulomatous Skin Infection Caused by Malassezia pachydermatis in a ...  -  Mar 14, 2006
The patient received 4 antituberculotics (isoniazid, rifampicin, pyrazinamide, and streptomycin sulfate) for 2 months because the results of direct ... Archives of Dermatology

Immunomodulation of Crassostrea gigas and Crassostrea virginica …  -  Aug 1, 2005
Ray's fluid thioglycollate medium (RFTM), sodium bicarbonate, glucose, galactose, trehalose, yeast extract, streptomycin sulfate, phenol red, ... Free with registration - Journal of Shellfish Research - AccessMyLibrary.com

Arkansas Regulations - NEW MEDICAID AID CATEGORY FOR …  -  Mar 16, 2007
...mg tablets Rifampin/300 mg capsules Levofloxacin/250 mg tablets Isoniazid/Rifampin 150/300 mg capsules Levofloxacin/500 mg tablets Streptomycin Sulfate, ... Pay-Per-View - Arkansas Regulations - Loislaw

Interleukin-1 modulation of human placental trophoblast proliferation....  -  Jan 1, 2006
MD) with 10% FBS and antibiotics (100 Unit/mL of penicillin G, 100 [micro]g/mL of streptomycin sulfate, and 0.25 [micro]g/mL of amphotericin B). ... Free with registration - Mediators of Inflammation - AccessMyLibrary.com

VANTAGE MAY CONTROL GRASS IN A GARDEN SETTING  -  Oct 21, 2005
I need to know if I have to cut off the infected branches before I spray or if I can just spray (I purchased streptomycin sulfate) to stop the blight from ... $2.95 - Aberdeen American News - NewsBank

Estradiol and bisphenol a stimulate androgen receptor and estrogen …  -  Jun 1, 2007
100 U penicillin G sodium/mL, 100 mg streptomycin sulfate/mL, and 0.25 mg fungizone/mL] with 10% (vol/vol) fetal bovine serum (FBS; US Bio-Technologies, ... $4.95 - Environmental Health Perspectives - ECNext

Induction of metamorphosis decreases nitric oxide synthase gene …  -  Dec 1, 2006
Veliger larvae were cultured as described by Couper and Leise (10) in 50% FIO/50% 0.2-[micro]m filtered seawater containing streptomycin sulfate and ... Free with registration - Biological Bulletin - AccessMyLibrary.com

The effect of egg quality on larval period and postlarval survival of...  -  Dec 1, 2005
...seawater (FSW) containing 150 [micro]g/mL of Penicillin G sodium and Streptomycin sulfate BP, respectively, without the addition of metamorphosis cues. ... Free with registration - Journal of Shellfish Research - AccessMyLibrary.com

The cytotoxicity of naturally occurring styryl lactones.  -  Feb 1, 2006
BRL) supplemented with 10% FBS (Gibco), 2 mg/ml sodium bicarbonate, 100 [micro]g/ml penicillin sodium salt and 100 [micro]g/ml streptomycin sulfate. ... Free with registration - Phytomedicine: International Journal of... - AccessMyLibrary.com

Federal Register 2007 - 72 FR 71898 Notice of Receipt of Requests to ...  -  Dec 19, 2007
000554-00141 Agsco Dustret "A" Streptomycin sulfate ------------------------- Maneb ... Pay-Per-View - Federal Register 2007 - Loislaw

Inheritance of resistance to Phomopsis seed decay in soybean PI 80837...  -  Nov 1, 2005
75 [micro]g/mL streptomycin sulfate, and acidified to pH 4.8 with lactic acid to prevent growth of bacteria. The percentage of seed infected with ... $4.95 - Crop Science - ECNext

Factiva Search  -  Apr 7, 2006
New Animal Drugs; Change of Sponsor; Soluble Bacitracin Methylene Disalicylate and Streptomycin Sulfate Oral Powder. 07 April, 2006 Federal Register ... Pay-Per-View - Federal Register - Factiva, from Dow Jones

Human metapneumovirus in Turkey poults.(RESEARCH)  -  Dec 1, 2006
2 mmol/L L-glutamine, nonessential amino acids, 100 IU/mL penicillin G sodium, and 100 [micro]g/mL streptomycin sulfate. Four genotypes of hMPV based on ... $4.95 - Emerging Infectious Diseases - ECNext

Induction of metamorphosis decreases nitric oxide synthase gene …  -  Dec 1, 2006
Veliger larvae were cultured as described by Couper and Leise (10) in 50% FIO/50% 0.2-[micro]m filtered seawater containing streptomycin sulfate and ... Pay-Per-View - Biological Bulletin - HighBeam Research

Distinct gene expression profiles in immortalized human urothelial...  -  Mar 1, 2006
2 mM L-glutamine, 100 U/mL of penicillin, and 100 [micro]g/mL streptomycin sulfate at 37[degrees]C in a humidified atmosphere containing 5% C[O.sub.2]. ... $4.95 - Environmental Health Perspectives - ECNext

Isolation and identification of microorganisms present in 53 dogs...  -  Jan 1, 2006
Some authors recommend such cultura media brain-heart agar with Penicillin G and Streptomycin Sulfate incubated at 37[degrees] to grow Malassezia [18]; ... Free with registration - Revista Científica de la Facultad de... - AccessMyLibrary.com

Brand Names/Synonyms:
Streptomycin Sulfate is also known by the following brand names and/or synonymsAmikin; G-Mycin; Garamycin; Jenamicin; Kantrex; Nebcin; Netromycin; Streptomycin; Streptomycin Sesquisulfate Hydrate; Streptomycin Sulfate; Streptomycin Sulphate; Streptomycin a Sulfate; Streptomycin, Sulfate Salt

Drug Category:
Streptomycin Sulfate is categorized under the following by the FDA: Anti-bacterial Agents; Aminoglycosides; ATC:A07AA04; ATC:J01GA01; ATC:S01AA15

Dosage Forms:
POWDER FOR SOLUTION

Absorption:
Not Available

Interactions:
Not Available



Chemical IUPAC Name:
5-(2,4-diguanidino-3,5,6-trihydroxy-cyclohexoxy)-4-[4,5-dihydroxy-6-(hydroxymethyl)-3-methylamino-tetrahydropyran-2-yl]oxy-3-hydroxy-2-methyl-tetrahydrofuran-3-carbaldehyde





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