Sulfamethoxazole

This page contains recent news articles, when available, and an overview of Sulfamethoxazole but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Sulfamethoxazole
(when available)

Pharmacology and use:
Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone. For the treatment of bronchitis, prostatitis and urinary tract infections

Mechanism Of Action:
Sulfonamides inhibit bacterial dihydrofolate synthetase, causing interference in the conversion of p-aminobenzoic acid (PABA) into folic acid. As folic acid is a coenzyme responsible for the transport of one-carbon fragments from one molecule to another, it is an essential component of bacterial development. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, the immediate next step, and therefore act synergistically with the sulfonamides.

News Articles on Sulfamethoxazole

READERS RESPOND  -  05 Jan 2010
Mrs H's medications include insulin, acetaminophen-codeine, fluticasone, furosemide, trimethoprim-sulfamethoxazole (for urinary tract prophylaxis after ... Journal of American Medical Association (subscription)

TMP-SMX for Prevention of Recurrent UTIs  -  ‎Jan 4, 2010‎
...recruited at four centers and randomized to either placebo or trimethoprim-sulfamethoxazole (TMP-SMX; 2 mg/kg/day TMP component) between 1998 and 2007. ... AAP Grand Rounds (registration)

Management of Hematospermia in the Family Practice Setting Reviewed  -  ‎Dec 28, 2009‎
When genitourinary tract infection is suspected, a 2-week course of fluoroquinolones, doxycycline, trimethoprim, or trimethoprim/sulfamethoxazole may be ... Medscape

Epiglottitis – Part 2  -  ‎Dec 29, 2009‎
Other drugs/chemicals used are ceftriaxone, cefuroxime, cefotaxime, cephalosporins, chloramphenicol, steroids, sulfamethoxazole, trimethoprim*. ... EmpowHer (blog)

Molecular characterisation of Vibrio cholerae O1 strains carrying an SXT/R391 ...  -  ‎Dec 29, 2009‎
They all contained strB, sulII, floR and the dfrA1 genes encoding resistance to streptomycin, sulfamethoxazole, chloramphenicol and trimethoprim ... 7thSpace Interactive (press release)

داء القطط .. بين الأم والطÙ?Ù„ (1-2)  -  ‎Dec 21, 2009‎
يعطى مرضى الإيدز جرعات وقائية من عقار التراى ميثوبريم- سلÙ?اميثوكسازول بجرعة مضاعÙ?Ø© لمرة واحدة trimethoprim-sulfamethoxazole حيث أن إصابتهم بداء القطط تكون ... الرأي

Trimethoprim-Sulfamethoxazole Use May Reduce UTIs in At-Risk Children  -  ‎Oct 29, 2009‎
October 29, 2009 — Use of long-term, low-dose trimethoprim-sulfamethoxazole may reduce urinary tract infections in at-risk children, according to the ... Medscape

Generic Name: Co-trimoxazole, trimethoprim, sulfamethoxazole, Septra, septra ...  -  ‎Nov 11, 2009‎
Each Bactrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole. Each Bactrim DS (double strength) tablet contains 160 mg trimethoprim and 800 ... Pattaya Daily News

Antibiotic Prophylaxis May Halt UTI Recurrence in Children Study finds low ...  -  ‎Oct 28, 2009‎
...trimethoprim-sulfamethoxazole suspension (2 mg of trimethoprim plus 10 mg of sulfamethoxazole per kilogram of body weight) or placebo for 12 months. ... ModernMedicine

Study Suggests Increased Risk of Birth Defects With UTI Treatments  -  ‎Nov 2, 2009‎
Sulfonamides such as sulfamethoxazole (combined with trimethoprim in Bactrim and Septra) and nitrofurantoins such as Macrobid, are commonly prescribed for ... MedPage Today

IDSA: Rare MRSA Strain Deadlier than Others  -  ‎Nov 3, 2009‎
...less susceptible (at P<0.01) than non-USA600 strains to trimethoprim/sulfamethoxazole (Bactrim, Septra) and gentamicin (various brand names). ... MedPage Today

Antibiotic Resistant E. Coli Urinary Tract Infection  -  ‎Nov 9, 2009‎
E. coli samples isolated from urine cultures were resistant to trimethoprim-sulfamethoxazole, which is a standard antibiotic combination used for UTI. ... EmpowHer (blog)

"I Wouldn't Wish SJS on My Worst Enemy"  -  ‎Nov 5, 2009‎
...(Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic used to treat ear infections, urinary tract and other infections. It is also associated with ... Lawyers and Settlements

Antibiotic resistance, CA-MRSA makes susceptibility testing essential  -  ‎Oct 19, 2009‎
Clindamycin, trimethoprim-sulfamethoxazole (TMP-SMX) and doxycycline are antibiotics used to manage CA-MRSA. Baker recommends performing a D test to ... Pediatric SuperSite

Consistent approach, realistic expectations serve as acne management cornerstones  -  ‎Oct 19, 2009‎
Tetracycline, erythromycin, doxycycline, monocycline and trimethoprim-sulfamethoxazole should be initiated for eight to 12 weeks and then tapered off to ... Pediatric SuperSite

Pharmaceutical Journal - Avoid folic acid antagonists in first trimester of ...  -  ‎Oct 20, 2009‎
In the study, 349 women were exposed to dihydrofolate reductase inhibitors such as trimethoprim/sulfamethoxazole, methotrexate and sulfasalazine, ... DeHavilland (press release) (subscription)

טיפול ×?נטיביוטי מונע מפחית שיעור הזיהומי×? החוזרי×? בדרכי השתן  -  ‎Oct 28, 2009‎
...ילדי×? עד גיל 18 ×¢×? זיהו×? חיידקי מוכח בדרכי השתן, חולקו ×?קר×?ית לקבוצת טיפול שקבלה רספרי×? ( 10 מ"×’ לק"×’ של ×” - SULFAMETHOXAZOLE שבתכשיר) משך 12 חודשי×? למול ... מרכז הרופאים המומחים

China imposes anti-dumping duties on imported sulfamethoxazole  -  Jun 16, 2007
BEIJING, June 15 (Xinhua) -- Chinese importers of sulfamethoxazole will have to pay anti-dumping duties as of Saturday to offset damages caused by ... 新�网

Xinhua - English  -  Jun 16, 2006
Sulfamethoxazole is one of a group of drugs called sulfonamides, which prevent the growth of bacteria in the body. Enditem. 新�网

Antibiotics: Tips for Safe Use  -  Aug 8, 2007
But two of the drugs on the list -- ciprofloxacin and sulfamethoxazole/trimethoprim -- are high-grade antibiotics that doctors usually reserve for ... ABC News

… on the Important Drug Interaction of Warfarin and Sulfamethoxazole  -  Nov 28, 2005
1 We strongly believe that sulfamethoxazole should be listed in the table ... The reality that many physicians may not recognize that sulfamethoxazole is a ... Archives of Internal Medicine

Sulfamethoxazole/trimethoprim DS tablets.  -  Jan 14, 2008
Sulfamethoxazole/trimethoprim DS tablets. American Health Packaging, Columbus, Ohio, (800) 707-4621, has two new items in its unit-dose product line. ... $9.94 - Drug Topics - Alacra Store

Popular antibiotic for acute cystitis flops in treatment trial  -  Mar 15, 2005
Rather, they turn back to the humble trimethoprim-sulfamethoxazole. "Trimethoprim-sulfamethoxazole should continue to be the firstline treatment for acute ... National Review of Medicine

Trimethoprim-Sulfamethoxazole Effective in Community-acquired MRSA …  -  May 10, 2006
By Rabiya S. Tuma, PhD. SAN FRANCISCO, CA -- May 10, 2006 -- Trimethoprim-sulfamethoxazole (TMP-SMX) is effective in treating skin and soft tissue ... DG News

Effectiveness of trimethoprim/sulfamethoxazole for children with...  -  May 1, 2007
CHRONIC ACTIVE (MUCOSAL) otitis media (COM) is a common infectious disease, affecting children in both developing and industrialized countries. ... $4.95 - Pediatrics - ECNext

… be leveling off'.(trimethoprim-sulfamethoxazole)(urinary tract...  -  Jul 15, 2005
...to the front-line, first-choice treatment of urinary tract infections (UTIs), trimethoprim-sulfamethoxazole (TMP-SMX)--has been documented worldwide. ... Free with registration - OB GYN News - AccessMyLibrary.com

Treatment of MRSA Infections With Older Molecules: A Reasonable …  -  Jun 11, 2007
4 Since the early 1970s, the efficacy of trimethoprim-sulfamethoxazole in severe S ... Trimethoprim/sulfamethoxazole for treatment of severe Staphylococcus ... Archives of Internal Medicine

Study examines three-day antibiotic regimens for treating bladder …  -  Feb 22, 2005
..."Trimethoprim-sulfamethoxazole should continue to be the first-line treatment ... In areas where the likelihood of trimethoprim-sulfamethoxazole resistance ... eurekalert.org

sulfamethoxazole | Definition of sulfamethoxazole | HighBeam.com: …  -  Jul 12, 2006
Find out what sulfamethoxazole means: The Oxford American College Dictionary has the definition of sulfamethoxazole. Research related newspaper, magazine, ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

… 'may be leveling off'.(trimethoprim-sulfamethoxazole)(urinary...  -  Jul 15, 2005
...trimethoprim-sulfamethoxazole)(urinary tract infections)(care and treatment)(Statistical data) ... find OB GYN News articles. Pay-Per-View - OB GYN News - HighBeam Research

Article: AP investigation details pharmaceuticals found in watersheds...  -  Mar 10, 2008
Atlanta: 10 (including caffeine, sulfamethoxazole, diltiazem, ... Las Vegas: 9 (including sulfamethoxazole, atenolol, trimethoprim, meprobamate, phenytoin, ... Pay-Per-View - Deseret News - HighBeam Research

… India.(NEWSDESK: Dumping)(sulfamethoxazole, Ministry of Commerce )...  -  Feb 26, 2007
NEWSDESK: Dumping)(sulfamethoxazole, Ministry of Commerce )(Brief article). China Chemical Reporter Feb 26 , 2007. On February 1st, the Ministry of Commerce ... $4.95 - China Chemical Reporter - ECNext

Antibacterial, systemic Sulfadiazine Sulfamethoxazole Sulfisoxazole …  -  Oct 27, 2005
Sulfonamides sul-FON-a-mides or sulfa medicines are used to treat infections. They will not work for colds, flu, or other virus infections. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Sulfamethoxazole and trimethoprim oral suspension, USP.  -  Feb 5, 2007
Sulfamethoxazole and trimethoprim oral suspension, USP. Teva Pharmaceuticals, North Wales, Pa., (888) TEVA-USA, is introducing sulfamethoxazole and ... $9.94 - Drug Topics - Alacra Store

Malaria Therapy; Trimethoprim-sulfamethoxazole is efficacious for …  -  Nov 20, 2005
2005 NOV 20 - (NewsRx.com) -- Trimethoprim-sulfamethoxazole is efficacious for the treatment of uncomplicated malaria in children. ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

Global emergence of trimethoprim/sulfamethoxazole resistance in …  -  Apr 1, 2007
Trimethoprim/sulfamethoxazole (TMP/SMX) resistance remains a serious threat in the treatment of Stenotrophomonas maltophilia infections. ... $4.95 - Emerging Infectious Diseases - ECNext

Lannett selling infection-fighting generic drug  -  Sep 14, 2005
Lannett Co. said Wednesday it has started selling a new generic drug product, sulfamethoxazole with trimethoprim, in single strength and double strength ... Philadelphia Business Journal

Sulfamethoxazole and trimethoprim oral suspension, USP.(NEW …  -  Feb 5, 2007
Teva Pharmaceuticals, North Wales, Pa., (888) TEVA-USA, is introducing sulfamethoxazole and trimethoprim oral suspension, USP. The product is bioequivalent ... $4.95 - Drug Topics - ECNext

… India.(NEWSDESK: Dumping)(sulfamethoxazole, Ministry of Commerce )...  -  Feb 26, 2007
NEWSDESK: Dumping)(sulfamethoxazole, Ministry of Commerce )(Brief article) ... find China Chemical Reporter articles. On February 1st, the Ministry of ... Pay-Per-View - China Chemical Reporter - HighBeam Research

… Administrative Code - 77 Ill. Adm. Code 790.8580 SULFAMETHOXAZOLE …  -  Aug 10, 2005
77 Ill. Adm. Code 790.8580 SULFAMETHOXAZOLE; TRIAMETHOPRIM (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

Does antibiotic prophylaxis prevent renal scarring in children with …  -  Sep 22, 2008
First, the prophylactic agent prescribed was sulfamethoxazole–trimethoprim. Sulfamethoxazole is known to affect fecal flora, which might increase the risk ... Nature.com

… Administrative Code - 77 Ill. Adm. Code 790.8540 SULFAMETHOXAZOLE …  -  Aug 10, 2005
77 Ill. Adm. Code 790.8540 SULFAMETHOXAZOLE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

Publix to offer free antibiotics.(Policy &amp; Practice)(Brief...  -  Sep 1, 2007
The antibiotics included in the program--amoxicillin, cephalexin, sulfamethoxazole/ trimethoprim (SMZ-TMP), ciprofloxacin (excluding Cipro XR), ... Free with registration - Pediatric News - AccessMyLibrary.com

å?¥åº·é†«ç™‚  -  Aug 30, 2006
...除了銀æ??葉藥物之外,醫院如果有太多處方使用cephalexinã€?sulfamethoxazole/trimethoprim æˆ?分藥物來治療中耳炎,超é?Žæ¨™æº–的部分也將ä¸?給付。 ... 自由時報

A case of prostatitis due to Burkholderia pseudomallei  -  Aug 2, 2006
...(1999) A comparison of chloramphenicol, trimethhoprim-sulfamethoxazole, and doxycycline with doxycycline alone as maintenance therapy for melioidosis. ... Nature.com

Patterns of pregnancy exposure to prescription FDA C, D and X drugs...  -  Feb 21, 2008
For example, our study found that trimethoprim/sulfamethoxazole is the most ... 19 Trimethoprim/sulfamethoxazole is a folic acid antagonist that may cause ... Nature.com

Long Island Technology Briefs: September 30, 2005  -  Sep 30, 2005
Interpharm Holdings Inc., based in Hauppauge, has begun production of Bactrim, the trademarked brand for an antibiotic made of sulfamethoxazole and ... $2.95 - Long Island Business News - NewsBank

Publix offers seven generic antibiotics for free.(Latebreakers)(Brief...  -  Aug 20, 2007
The free antibiotics are all generics: amoxicillin, cephalexin, sulfamethoxazole/ trimethoprim, ciprofloxacin (excluding ciprofloxacin XR), penicillin VK, ... $4.95 - Drug Topics - ECNext

Emergency Medicine Resident Journal Review  -  May 30, 2008
This open-label study compared the efficacy of a five day course of nitrofurantoin to three days of trimethoprim-sulfamethoxazole in 338 18 to 45 year-old ... Medscape

Article: Nitrofurantoin comeback for uncomplicated UTI.(Gynecology)( …  -  Feb 1, 2006
Study finds TMP/SMX regimen prevents PCP in AIDS patients ... of trimethoprim and sulfamethoxazole (TMP/SMX) for long periods actually prevents ... Pay-Per-View - OB GYN News - HighBeam Research

Article: Consider nitrofurantoin in bacterial-resistance era. -...  -  Feb 15, 2006
Study finds TMP/SMX regimen prevents PCP in AIDS patients ... of trimethoprim and sulfamethoxazole (TMP/SMX) for long periods actually prevents ... Pay-Per-View - Internal Medicine News - HighBeam Research

Acute, life-threatening hypoglycemia associated with haloperidol in a...  -  Oct 24, 2005
From the pre-existing medications, only trimethoprim/sulfamethoxazole, which had been administered to this patient for more than 3 months at relatively high ... Nature.com

Company Profile Report  -  Aug 2, 2008
Trimethoprim/Sulfamethoxazole. Respiratory System. Bronchitis. Diaminopyrimidines/Sulfonamides ... Trimethoprim/Sulfamethoxazole. Musculoskeletal System ... $50.00 - Revere Reports - Revere

China may impose dumping duty on India for sulphamethoxazole exports  -  Sep 14, 2006
Virchow Laboratories Limited, Hyderabad is the largest producer of sulfamethoxazole in the world with an output of 4800 MT per annum and will be the most ... pharmabiz.com

Company Profile Report  -  Aug 2, 2008
Trimethoprim/Sulfamethoxazole. Respiratory System. Bronchitis. Diaminopyrimidines/Sulfonamides ... Trimethoprim/Sulfamethoxazole. Musculoskeletal System ... $50.00 - Revere - Alacra Store

Article: Resistance increasing to standard UTI treatment.(Infectious ...  -  Jul 1, 2005
SAN FRANCISCO ... line treatment for urinary tract infections in many ... sulfamethoxazole (TMP-SMZ), Dr. John ... new guidelines on urinary tract ... Pay-Per-View - Family Practice News - HighBeam Research

Drug-Resistant Staph - Infections - Methicillin-Resistant Staphylococc...  -  Oct 28, 2007
Others may also be treated with with the antibiotics clindamycin, trimethoprim-sulfamethoxazole, doxycycline, minocycline, rifampin or linezolid. ... New York Times

Free-living Canada Geese and antimicrobial resistance.(DISPATCHES)  -  Jun 1, 2005
Cooperative Wildlife Disease Study were resistant to sulfamethoxazole, and 18.1% were resistant to both sulfamethoxazole and streptomycin (8). ... $4.95 - Emerging Infectious Diseases - ECNext

Another Option for Uncomplicated Cystitis  -  Nov 16, 2007
Five-day courses of nitrofurantoin are equivalent clinically and microbiologically to a three-day course of trimethoprim-sulfamethoxazole (TMP/SMX) for ... Renal and Urology News

Article: Highly recommended.(News) - The Journal (Newcastle, England)...  -  Apr 28, 2006
Medical Letter on the CDC & FDA; February 3, 2002 ; 700+ words ... ... trimethoprim-sulfamethoxazole is highly recommended for urinary tract infection (UTI ... Pay-Per-View - The Journal - HighBeam Research

Cirrhosis and chronic liver failure: Part II. Complications and...  -  Sep 1, 2006
Patients who survive an episode of spontaneous bacterial peritonitis should receive long-term prophylaxis with norfloxacin or trimethoprim/sulfamethoxazole. ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Urinary Tract Infection Medications - Urinary Tract Infection Health ...  -  Oct 2, 2008
As more bacteria have become resistant to the standard UTI treatment trimethoprim-sulfamethoxazole (TMP-SMX), more doctors have prescribed quinolone ... New York Times

China slaps penal duty on antibiotic  -  Jun 18, 2007
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic. ... China started its anti-dumping investigation on sulfamethoxazole last June and imposed ... Calcutta Telegraph

Sinusitis Medications - Sinusitis Health Information - NY Times Health  -  Jan 23, 2008
Trimethoprim-sulfamethoxazole (Bactrim, Cotrim, Septra) is another first-line antibiotic for sinusitis. It is less expensive than amoxicillin and ... New York Times

Pneumocystis pneumonia in HIV-positive adults, Malawi (1).( …  -  Feb 1, 2007
At the time of the study, in Malawi, antiretroviral therapy (ART) was rarely used, and trimethoprim-sulfamethoxazole prophylaxis was not recommended. ... $4.95 - Emerging Infectious Diseases - ECNext

Cystitis - Acute Bacterial Medications - Cystitis - Acute Bacterial...  -  Sep 18, 2008
As more bacteria have become resistant to the standard UTI treatment trimethoprim-sulfamethoxazole (TMP-SMX), more doctors have prescribed quinolone ... New York Times

sulfadiazine | Definition of sulfadiazine | HighBeam.com: Online …  -  Jul 12, 2006
Her last ... well-documented allergy to sulfamethoxazole (also a sulfonamide ... Sulfamethoxazole ... Cofatrim Forte, Cotrim, Septra, Sulfatrim): the ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Abstract and Introduction  -  Feb 24, 2005
Efficacy of trimethoprim-sulfamethoxazole prophylaxis to decrease morbidity ... Early chemoprophylaxis with trimethoprim-sulfamethoxazole for HIV-1 infected ... Medscape

Community-Associated Methicillin-Resistant Staphylococcus aureus Skin...  -  Apr 23, 2007
13-18 Prior studies have shown that CA-MRSA isolates are susceptible to trimethoprim-sulfamethoxazole combination, clindamycin, fluoroquinolones, ... Archives of Internal Medicine

Three-Day Antibiotic Regimens for Treating Bladder Infection in Women  -  Feb 17, 2005
..."Trimethoprim-sulfamethoxazole should continue to be the first-line treatment ... In areas where the likelihood of trimethoprim-sulfamethoxazole resistance ... newswise.com

Which UTI therapies are safe and effective during breastfeeding?( …  -  Mar 1, 2007
Trimethoprim/sulfamethoxazole (TMP/SMX) has a high success rate in eradicating bacteriuria for women with urinary tract infection and is compatible with ... Free with registration - Journal of Family Practice - AccessMyLibrary.com

Community-acquired extended-spectrum [beta]-lactamase producers, …  -  Jul 1, 2007
These organisms may be resistant to most or all antimicrobial agents commonly used to treat UTIs, such as ciprofloxacin, trimethoprim-sulfamethoxazole, ... Free with registration - Emerging Infectious Diseases - AccessMyLibrary.com

HIV-Related Lung Diseases  -  Mar 23, 2007
Trimethoprim-sulfamethoxazole is the most effective medication for this purpose; other medications such as dapsone, pentamidine and atovaquone can be used ... Intelihealth.com

Researchers Identify Risk Factors for Nocardia infection After Solid...  -  Apr 3, 2007
Further, use of low-dose trimethoprim-sulfamethoxazole for PCP prophylaxis is in fact unreliable in preventing Nocardia infection in organ transplant ... DG News

Sulfonamide and trimethoprim for urinary tract infections (UTIs)  -  Jun 15, 2007
Sulfamethoxazole is an antibiotic that comes in tablet or syrup form to take by ... Sulfamethoxazole with trimethoprim are combinations of two different ... MSN Health & Fitness

Survey: Three pharmaceutical drugs are found in Tucson water  -  Mar 10, 2008
Carbamazepine is a mood stabilizing drug, sulfamethoxazole is an antibiotic. Dehydronifedipine is a byproduct of a popular heart medication. ... Tucson Citizen

Sulfonamides and Phenazopyridine (Systemic).  -  May 1, 2006
For (sulfamethoxazole and phenazopyridine combination ): Adults and children 12 years of age and older: 2 grams of sulfamethoxazole and 400 mg of ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Rise in E. coli resistance in UTIs starting to slow.(Infectious...  -  Sep 15, 2005
Urinary tract infections caused by drug ... trimethoprim-sulfamethoxazole (TMP-SMZ)-resistant E. coli ... humans, and 14 of those were TMP-SMZ resistant. ... Pay-Per-View - Internal Medicine News - HighBeam Research

Randomized controlled trial of standard versus double dose …  -  Jan 1, 2005
...same appearance and taste: standard strength (200 mg sulfamethoxazole plus 40 ... (400 mg sulfamethoxazole plus 80 mg trimethoprim per 5 ml suspension). ... $4.95 - Bulletin of the World Health Organizatio... - ECNext

Atypical infections in tsunami survivors.  -  Oct 1, 2005
The patient was treated with trimethoprim-sulfamethoxazole for 10 weeks. On week 8 of hospitalization, persistent fever and progressive alteration of ... $4.95 - Emerging Infectious Diseases - ECNext

Empyema thoracis from Salmonella choleraesuis.(LETTERS)(Letter to the...  -  Sep 1, 2005
Susceptibilities of Salmonella isolates to ampicillin, cefotaxime, chloramphenicol, ciprofloxacin, and trimethoprim-sulfamethoxazole were determined by the ... $4.95 - Emerging Infectious Diseases - ECNext

Bladder Infection; Study finds amoxicillin-clavulanate regimen less …  -  Mar 19, 2005
..."Trimethoprim-sulfamethoxazole should continue to be the first-line treatment for acute ... "In areas where the likelihood of trimethoprim-sulfamethoxazole ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Article: In 2 trials, combination gel speeds acne relief.(Clinical...  -  Oct 1, 2005
SAN DIEGO -- Clindamycin and trimethoprim-sulfamethoxazole ... according to one expert "The issue with clindamycin is that if you have big loads of ... Pay-Per-View - Pediatric News - HighBeam Research

Rhodococcus equi infection after alemtuzumab therapy for T-cell …  -  Dec 1, 2007
Due to variable susceptibility to trimethoprim-sulfamethoxazole, the prophylaxis regimen used after alemmzumab therapy will not prevent R. equi infection in ... $4.95 - Emerging Infectious Diseases - ECNext

Community-acquired extended-spectrum [beta]-lactamase producers, …  -  Jul 1, 2007
These organisms may be resistant to most or all antimicrobial agents commonly used to treat UTIs, such as ciprofloxacin, trimethoprim-sulfamethoxazole, ... $4.95 - Emerging Infectious Diseases - ECNext

Staphylococcal cassette chromosome mec in MRSA, Taiwan.( …  -  Mar 1, 2007
Because the major MRSA clones isolated in 1994-2003 are more resistant to antimicrobial drugs, especially fluoroquinolones and trimethoprim-sulfamethoxazole ... Free with registration - Emerging Infectious Diseases - AccessMyLibrary.com

IDSA releases guidelines for the diagnosis and treatment of skin and...  -  Oct 1, 2006
Patients with previous severe reactions may be treated with oral or intravenous doxycycline (Vibramycin), trimethoprim/sulfamethoxazole (TMP/SMX; Bactrim, ... Free with registration - American Family Physician - AccessMyLibrary.com

Cephalexin last on list for CA-MRSA infections.(Skin Disorders) |...  -  Aug 15, 2008
Cephalexin does not treat CA-MRSA; trimethoprim/sulfamethoxazole does not treat ... Choosing between trimethoprim/sulfamethoxazole and clindamycin remains a ... Pay-Per-View - Family Practice News - HighBeam Research

Community case of methicillin-resistant Staphylococcus aureus...  -  Jan 1, 2006
...other linezolid, drugs to which vancomycin, MSSA is erythromycin, potentially clindamycin, susceptible trimethoprim- sulfamethoxazole, fluoroquinolones, ... Free with registration - Emerging Infectious Diseases - AccessMyLibrary.com

Cephalexin of little use in CA-MRSA.(News) | Article from Skin &...  -  Jul 1, 2008
Cephalexin does not treat CA-MRSA; trimethoprim/sulfamethoxazole does not treat ... Choosing between trimethoprim/sulfamethoxazole and clindamycin remains a ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Drug-resistant diarrheogenic Escherichia coli, Mexico.(DISPATCHES)  -  Aug 1, 2005
Efficacy of trimethoprim-sulfamethoxazole in treatment of acute diarrhea in a Mexican pediatric population. J Pediatr. 1987:110:960-5. ... $4.95 - Emerging Infectious Diseases - ECNext

Staphylococcal cassette chromosome mec in MRSA, Taiwan.( …  -  Mar 1, 2007
Because the major MRSA clones isolated in 1994-2003 are more resistant to antimicrobial drugs, especially fluoroquinolones and trimethoprim-sulfamethoxazole ... $4.95 - Emerging Infectious Diseases - ECNext

Breast Abscess Bacteriologic Features in the Era of Community...  -  Apr 27, 2007
All MRSA was sensitive to clindamycin, trimethoprim-sulfamethoxazole, and linezolid. Only 2 patients (29%) were sensitive to levofloxacin. ... Archives of Surgery

Therapy for acute bacterial sinusitis.(DRUG UPDATE)  -  Mar 1, 2005
Diarrhea a common side effect, especially at higher doses. trimethoprim/ Available in generic and trade formulations. sulfamethoxazole Top choice for mild ... Free with registration - OB GYN News - AccessMyLibrary.com

ANCA-negative glomerulonephritis associated with nonasthmatic Churg– …  -  Mar 31, 2008
He also received oral clotrimazole and combined oral sulfamethoxazole and trimethoprim for prophylaxis against candidiasis and pneumonia, respectively. ... Nature.com

KPC type [beta]-lactamase, rural Pennsylvania.(Letter to the editor)  -  Oct 1, 2006
She had received trimethoprim/sulfamethoxazole and levofloxacin for treatment for urinary tract infections in the month before the KPC-producing strain was ... $4.95 - Emerging Infectious Diseases - ECNext

Invasive pneumococcal disease in adult hematopoietic stem cell …  -  Jan 7, 2008
Trimethoprim-sulfamethoxazole (TMP/SMX) prophylaxis for Pneumocystis jiroveci (one double-strength tablet three times per week) was used in all patients ... Nature.com

Melioidosis in New Caledonia.  -  Oct 1, 2005
The patient continued to receive trimethoprim/sulfamethoxazole on a long-term basis. In June 2004, a 67-year-old woman with a history of diabetes mellitus ... $4.95 - Emerging Infectious Diseases - ECNext

Prostatitis; Researchers suggest treatment course for patients with …  -  Sep 5, 2006
Second-line conventional medication with sulfamethoxazole-trimethoprim or ... Fluoroquinolones or sulfamethoxazole-trimethoprim should not be employed in ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Fever plus abdominal pain may indicate CSD complication.(Infectious …  -  Sep 1, 2007
All patients were treated with gentamicin, rifampin, and/or trimethoprim / sulfamethoxazole in various combinations. Defervescence occurred within 1-5 days ... $4.95 - Pediatric News - ECNext

Malaria; Researchers from the United States and Gabon report details...  -  Oct 30, 2006
Study 2: Trimethoprim-sulfamethoxazole is efficacious for the treatment of ... "In Malawi, trimethoprim-sulfamethoxazole (TS) is the recommended first-line ... Pay-Per-View - OBGYN & Reproduction Week - Factiva, from Dow Jones

Stenotrophomonas maltophilia in salad.(LETTERS)(Letter to the Editor)  -  Jul 1, 2005
However, as with most strains of clinical origin, all the isolates tested here remained susceptible to trimethoprim-sulfamethoxazole and minocycline. ... $4.95 - Emerging Infectious Diseases - ECNext

Antibiotic Resistance; Antimicrobial resistance is common in Shiga...  -  Dec 6, 2005
..."Ninety-three (34%) of the isolates were resistant to streptomycin, followed by 89 (32%) to sulfamethoxazole, 83 (30%) to tetracycline, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Aspergillosis; SMX might be effective against Aspergillus  -  Jul 26, 2005
The combination of sulfamethoxazole and trimethoprim (TMP) has been used extensively for the treatment and prophylaxis of infections by various microbes," ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

'No magic bullet' among MRSA treatments.(Dermatologic Therapy) | …  -  Dec 1, 2006
Trimethoprim / sulfamethoxazole (Bactrim) has a long record of clinical use. ... Of note, trimethoprim/sulfamethoxazole has been found inferior to ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Drug Resistance; Antimicrobial resistance found in Shiga toxin...  -  Sep 12, 2005
..."Ninety-three (34%) of the isolates were resistant to streptomycin, followed by 89 (32%) to sulfamethoxazole, 83 (30%) to tetracycline, ... Pay-Per-View - Anti-Infectives Week - Factiva, from Dow Jones

Vibrio cholerae SXT element, Laos.(Letters)(Letter to the Editor)  -  Feb 1, 2005
A new type of conjugative transposon encodes resistance to sulfamethoxazole, trimethoprim, and streptomycin in Vibrio cholerae O139. J Bacteriol. ... $4.95 - Emerging Infectious Diseases - ECNext

Scientists refute study linking antibiotic resistance to UTIs.(Researc...  -  Jan 24, 2005
..."The drugs in question in the study, trimethoprim and sulfamethoxazole, are not approved by FDA for use in food animals. It could not have been administered ... Pay-Per-View - Food Chemical News - Factiva, from Dow Jones

Article: More options for HIV.(Clinical Capsules)(Human …  -  Feb 1, 2005
Trimethoprim and sulfamethoxazole (TMP/SMX), clindamycin, and minocycline ... infections. "You can use something wimpy like TMP/SMX with a "small drained ... Pay-Per-View - Pediatric News - HighBeam Research

US Centers for Disease Control and Prevention; Researchers' findings ...  -  Dec 21, 2005
Study 1: Trimethoprim-sulfamethoxazole is efficacious for the treatment of ... "In Malawi, trimethoprim-sulfamethoxazole (TS) is the recommended first-line ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Distribution and characteristics of Escherichia coli clonal group...  -  Jan 1, 2005
3%; p < 0.001) and those resistant to trimethoprim-sulfamethoxazole (10% vs. ... Conventional and molecular epidemiology of trimethoprim-sulfamethoxazole ... $4.95 - Emerging Infectious Diseases - ECNext

Daptomycin use in infants: report of two cases with peak and trough...  -  Aug 27, 2007
The organism was also resistant to clindamycin, erythromycin and trimethoprim/sulfamethoxazole and it was susceptible to rifampin. ... Nature.com

Incidence of Clostridium difficile-associated diarrhea before and...  -  Jan 23, 2006
Trimethoprim/sulfamethoxazole or an equivalent medication, ... Prophylaxis with trimethoprim/sulfamethoxazole was resumed when the ANC reached 500 cells/mm ... Nature.com

Nasopharyngeal Decolonization of Methicillin-Resistant Staphylococcus...  -  Jan 14, 2005
...of intranasal mupirocin, arbekacin inhalation, and oral sulfamethoxazole/trimethoprim in all 24 patients, significantly reduced peristomal infections. ... Nature.com

Early-onset sepsis with Staphylococcus auricularis in an extremely...  -  Feb 1, 2007
...cefazolin, clindamycin, erythromycin and sulfamethoxazole. Given the unusual susceptibility pattern to the CoNS usually encountered in our hospital, ... Nature.com

Anti-glomerular basement membrane disease in an HIV-infected patient  -  Mar 6, 2007
The primary diagnosis at that time was acute interstitial nephritis secondary to trimethoprim–sulfamethoxazole (co-trimoxazole) or rifampicin treatment. ... Nature.com

Antibiotics for sinusitis  -  Aug 15, 2008
Trimethoprim-sulfamethoxazole may be prescribed for people who are allergic to amoxicillin. Other antibiotics may be prescribed to treat bacterial ... WebMD

Brand Names/Synonyms:
Sulfamethoxazole is also known by the following brand names and/or synonymsA047; Apo-Sulfamethoxazole; Azo Gantanol; Azo-Gantanol; Bactrim; Bactrim Ds; Bactrim Pediatric; Bactrimel; Co-Trimoxazole; Cotrim; Cotrim D.S.; Eusaprim; Fectrim; Gamazole; Gantanol; Gantanol-Ds; MS 53; Metoxal; Radonil; SIM; Septra; Septra Ds; Septra Grape; Septran; Septrin; Simsinomin; Sinomin; Sulfamethalazole; Sulfamethoprim; Sulfamethoprim-Ds; Sulfamethoxazol; Sulfamethoxazole; Sulfamethoxazole & Trimethoprim; Sulfamethoxazole Trimethoprim; Sulfamethoxizole; Sulfamethylisoxazole; Sulfatrim; Sulfatrim Pediatric; Sulfatrim-Ds; Sulfatrim-Ss; Sulfisomezole; Sulmeprim; Sulmeprim Pediatric; Sulpha-Methoxizole; Sulphamethalazole; Sulphamethoxazol; Sulphamethoxazole; Sulphamethoxazole Bp 98; Sulphamethylisoxazole; Sulphisomezole; Trib; Trimeth/Sulfa; Trimetoprim-Sulfa; Urobak; Uroplus Ds; Uroplus Ss

Drug Category:
Sulfamethoxazole is categorized under the following by the FDA: Anti-Infectives; Sulfonamides; ATC:J01EC01

Dosage Forms:
TABLET

Absorption:
Sulfamethoxazole is rapidly absorbed following oral administration.

Interactions:
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Chemical IUPAC Name:
4-amino-N-(5-methyloxazol-3-yl)-benzenesulfonamide





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