Sulfanilamide

This page contains recent news articles, when available, and an overview of Sulfanilamide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Sulfanilamide
(when available)

Pharmacology and use:
Sulfanilamide is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus. For the treatment if vaginitis and vulvovaginitis

Mechanism Of Action:
Sulfanilamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.

News Articles on Sulfanilamide

2nd Amendment advocates worry over opinions of OSHA nominee  -  ‎Nov 11, 2009‎
On the heels of the Elixir Sulfanilamide scandal, in which a medicine manufactured with antifreeze killed scores of children, Congress passed the Food, ... WND.com

The Problem and Solution to Health Care - Page 3  -  ‎Oct 20, 2009‎
Prior to this, the largest catastrophic incident of death caused by an unsafe prescription drug, Elixir Sulfanilamide, was that of 107 individuals (8). ... Libertarian Solution

sulfanilamide | Definition of sulfanilamide | HighBeam.com: Online …  -  Jul 12, 2006
Find out what sulfanilamide means: The Oxford American College Dictionary has the definition of sulfanilamide. Research related newspaper, magazine, ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

… Administrative Code - 77 Ill. Adm. Code 790.8590 SULFANILAMIDE ( …  -  Aug 10, 2005
77 Ill. Adm. Code 790.8590 SULFANILAMIDE (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

Pennsylvania Statutes - SULFANILAMIDE AND DERIVATIVES  -  Jul 25, 2008
SULFANILAMIDE AND DERIVATIVES. Copyright © 2008 Loislaw.com, Inc. All Rights Reserved. Pay-Per-View - Pennsylvania Statutes - Loislaw

Nevada Statutes - NRS 585.480 Misbranded drugs and devices: Drug …  -  Aug 15, 2005
NRS 585.480 Misbranded drugs and devices: Drug containing amidopyrine, barbituric acid, cinchophen, dinitrophenol or sulfanilamide sold without prescription ... Pay-Per-View - Nevada Statutes - Loislaw

The Why Files | 2. Diethylene glycol: Sweet 'n deadly  -  Jul 12, 2007
Soon after it was compounded in 1937, Elixir of Sulfanilamide killed bacteria -- and people. Many of the 105 victims were children. Photo: FDA ... Why Files

CHINA LEVIED ANTI-DUMPING TAXES ON INDIAN DRUG COMPANIES …  -  Jun 19, 2007
Sulfanilamide first mixture is the important raw materials for the ... Indian companies carry sulfanilamide first mixture products to China and sell them in ... Pay-Per-View - AsiaInfo Services - HighBeam Research

CHINA LEVIED ANTI-DUMPING TAXES ON INDIAN DRUG COMPANIES …  -  Jun 19, 2007
Sulfanilamide first mixture is the important raw materials for the ... Indian companies carry sulfanilamide first mixture products to China and sell them in ... Pay-Per-View - AsiaInfo Services - HighBeam Research

COMMENTARY - Curtain rises on antibiotic era  -  Nov 19, 2007
In the test tube, the prontosil dye clung to the sulfanilamide, thus preventing it from exerting its bacteriocidal effects. In the mammalian body, however, ... Pay-Per-View - Providence Journal - ProQuest Archiver

sulfa drug -- Britannica Online Encyclopedia  -  Jun 19, 2008
By the 1940s sulfanilamide was a widely used drug. During World War II white sulfanilamide powders became standard in first aid kits for the treatment of ... Subscription - Encyclopedia Britannica

Antibiotics and Drug Discovery  -  Apr 5, 2005
One of the halves, subsequently named sulfanilamide, turned out to be a fully ... The discovery of sulfanilamide marked the beginning of the search for ... SciScoop

Article: CHINA LEVIED ANTI-DUMPING TAXES ON INDIAN DRUG …  -  Jun 19, 2007
Sulfanilamide first mixture is the important raw materials for the production of sulfanilamide medicine and is widely used. Indian ... ... Pay-Per-View - AsiaInfo Services - HighBeam Research

Inhibition of enzymes  -  Jun 5, 2008
Inhibitors such as sulfanilamide are called anti-metabolites. Sulfanilamide and similar compounds that kill a pathogen without harming its host are now ... Subscription - Encyclopedia Britannica

Protecting Us - But Not From Tobacco  -  Dec 21, 2006
The FDCA was a response to the 1937 Elixir Sulfanilamide disaster, ... Elixir Sulfanilamide happens to be safe when taken in the form of a pill, ... Nebraska StatePaper.com

New FDA rules could cut cost and time for drug approvals  -  Jan 23, 2006
...s Elixir Sulfanilamide was an effective treatment for sore throats in people with ... s Elixir Sulfanilamide. "The net result was the Food and Drug ... Bizjournals.com

pharmaceutical industry  -  Jun 15, 2008
When sulfanilamide was introduced into therapy, one of the side effects it produced ... Subsequently, many sulfanilamide-like compounds were synthesized and ... Subscription - Encyclopedia Britannica

ADME-Tox Gets Faster, Cheaper, and Safer  -  Jan 1, 2007
In June 1937, a chemist at the SE Massengill Company developed a liquid formulation of the antibiotic sulfanilamide, to treat pediatric streptococcal ... Drug Discovery & Development

Figure 1 : Ceruloplasmin is a NO oxidase and nitrite synthase that …  -  Aug 13, 2006
...(a) NO signals measured in plasma with and without treatment with acid sulfanilamide (AS) (to selectively remove nitrite) and mercuric chloride (HgCl 2 ... Nature.com

history of medicine Sulfonamide drugs  -  Jun 13, 2008
Some stood the test of time; others, like the original sulfanilamide and its immediate successor, sulfapyridine, were replaced by safer and more powerful ... Subscription - Encyclopedia Britannica

How the pet food scare affects global health  -  May 6, 2007
In 1937, the Tennessee pharmaceutical firm SE Massengill Co. used diethylene glycol in its Elixir Sulfanilamide, a drug for streptococcal infections. ... Bulletin of the Atomic Scientists

Nigeria: Diethylene Glycol, Killer On the Prowl  -  Dec 2, 2008
It is on record that the lethal effects of the chemical as a mass poisoner, dates back to the 1937 Elixir Sulfanilamide disaster in the USA, ... AllAfrica.com

FDA at 100: alumni take its temperature: as the Food and Drug …  -  May 1, 2006
Cases in point: The victims of the sulfanilamide poisoning were primarily children, thalidomide hurt fetuses and the risks of DES and the Dalkon Shield led ... Free with registration - Medical Marketing & Media - AccessMyLibrary.com

Figure 6 : Catalytic generation of N: 2: O: 3: by the concerted...  -  Nov 4, 2007
Before injection into tri-iodide (see Methods), aliquots of the trap vessel solution were pretreated with either acidified sulfanilamide alone () or with ... Nature.com

Laws requiring safe drugs inspired by 1937 tragedy .  -  Oct 6, 2005
Elixir Sulfanilamide provided the emotionally wrenching case history the bill's ... That year, the also decided that sulfanilamide, among other power ful ... The Day - Google News Archive

WHO expert committee on specifications for pharmaceutical preparations...  -  Aug 1, 2005
...sulfacetamide 100mg 196200 9930419 sulfamethoxazole 100mg 179092 9930420 sulfamethoxypyridazine 100mg 178079 9930421 sulfanilamide 100mg 179094 9930424 ... Free with registration - Technical Report Series - AccessMyLibrary.com

Article: Tainted!(Consumers' Post) - Manila Bulletin | HighBeam...  -  May 27, 2007
The most wellknown incident of diethylene glycol poisoning was the 1937 Elixir Sulfanilamide tragedy, in which 107 people in the US died after taking ... Pay-Per-View - Manila Bulletin - HighBeam Research

Aged Garlic Extract Maintains Cardiovascular Homeostasis in Mice and ...  -  Mar 12, 2006
Arginine, zinc sulfate, phosphoric acid, sulfanilamide, N-1- naphthylethylenediamine, sodium nitrite, potassium nitrate, sodium pyruvate, sodium chloride, ... RedOrbit

USP Modifies Glycerin Monograph: More Requirements for Pharma  -  Apr 18, 2008
Diethylene glycol was responsible for 107 poisoning deaths in 1937 when SE Massengill mixed its antibiotic sulfanilamide with the chemical to make a liquid ... FDA news - FDA news (subscription)

Transition diagrams for a liquid crystalline thermoset containing a...  -  May 1, 2006
However, in the case of a tetrafunctional amine, such as sulfanilamide (SAA), ... Sulfanilamide (SAA) and 1-methyl imidazole (MI) were used as curing agents ... Free with registration - Polymer Engineering and Science - AccessMyLibrary.com

A versatile method for the quantitative determination of [.sup.[beta]....  -  May 1, 2005
Although it is not related to the chemical structure of the C-5HTs, sulfanilamide has alternatively been used as an internal standard [14], ... $9.94 - European Food Research and Technology A - Alacra Store

Article: Transition diagrams for a liquid crystalline thermoset...  -  May 1, 2006
However, in the case of a tetrafunctional amine, such as sulfanilamide (SAA), ... Sulfanilamide (SAA) and 1-methyl imidazole (MI) were used as curing agents ... Pay-Per-View - Polymer Engineering and Science - HighBeam Research

sulfonamide -- Britannica Online Encyclopedia  -  Jun 19, 2008
The bacteriostatic sulfonamide drugs, often called sulfa drugs, include sulfanilamide and numerous compounds closely related to it. ... Subscription - Encyclopedia Britannica

Except where noted otherwise, data are given for  -  Dec 21, 2007
For example, sulfonation of aniline produces sulfanilic acid, which can be converted to sulfanilamide. Sulfanilamide is one of the sulfa drugs that were ... chemie.de

Article: SSP INITIATES FIRST MEDICINE ANTI-DUMPING CASE IN …  -  Jun 21, 2006
Gao Shang, the spokesman of SSP directorate said sulfanilamide is one of the ... It is known that the sales price of the sulfanilamide remained at CNY 2 per ... Pay-Per-View - AsiaInfo Services - HighBeam Research

sulfa- | Definition of sulfa- | HighBeam.com: Online Dictionary  -  Jul 12, 2006
...sulfa- ( chiefly Brit. also sulph- ) • comb. form in names of drugs derived from sulfanilamide. ORIGIN: abbreviation of sulfanilamide . ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

Victor A. McKusick, 86; Johns Hopkins physician pioneered genetics …  -  Jul 24, 2008
Massachusetts General Hospital in Boston before he was finally treated with the antibiotic sulfanilamide, which had been introduced only a year earlier. ... Los Angeles Times

Navy Hero to Earn Medal for 1942 Surgery at Sea  -  Feb 19, 2005
Rummaging in the medicine chest, they found sulfanilamide tablets and ground them to powder. One thing was lacking: there was no means of holding open the ... NPR

Panama spits out 'poison' Chinese toothpaste  -  May 22, 2007
Back in 1937, the Elixir Sulfanilamide Incident claimed more than 100 lives in 15 US states, prompting the rapid introduction of the Federal Food, Drug, ... Register

Sulfa-Sulfites Confusion  -  Oct 26, 2005
The sulfa drugs -- sulfanilamide, sulfathiazole, sulfadiazine and literally thousands of others -- are a class of organic (carbon-containing) chemical ... Pay-Per-View - Washington Post - ProQuest Archiver

We need more quality control, whatever the price  -  Jul 5, 2007
...a year after more than 100 Americans died when a pharmaceutical manufacturer used sulfanilamide with a DEG solvent as part of its "elixir. ... Deseret News

Sulfa-Sulfites Confusion | Article from The Washington Post |...  -  Oct 26, 2005
The sulfa drugs -- sulfanilamide, sulfathiazole, sulfadiazine and literally thousands of others -- are a class of organic (carbon- containing) chemical ... Pay-Per-View - Washington Post - HighBeam Research

ABS-CBN News Online Beta  -  Sep 23, 2008
...for decades following events in 1937 where 107 people died after they took the drug Elixir Sulfanilamide, which has been found to contain the solvent. ... ABS CBN News

Medicine's First Miracle Drug  -  Sep 30, 2006
Sulfanilamide, called sulfa by the chemists who synthesized it around 1900, sat on all dyers' shelves, the proprietary patents having long expired. ... Wall Street Journal

Seeking the sweet taste of success  -  Aug 10, 2005
He traced the sweetness back to a two-ringed chemical called benzoic acid sulfanilamide. Fully 300 times sweeter than sugar, it is indigestible by the body, ... The Standard

A Genetics Pioneer Who Mapped the Inner World  -  Jul 24, 2008
...(It was cured with sulfanilamide, which had just arrived in the medical armamentarium). After college and medical school, both shortened by World War II, ... Pay-Per-View - Washington Post - ProQuest Archiver

The sweet spot: Researchers seek ways to reduce sugar  -  Aug 17, 2005
He traced the sweetness back to a two-ringed chemical called benzoic acid sulfanilamide. Fully 300 times sweeter than sugar, it is indigestible by the body, ... Seattle Times

UNTESTED MEDICINE  -  Oct 16, 2007
Sulfanilamide, a drug used to treat strep infections, had shown great success as a cure in the 1930s and was used safely in tablet and powder form. ... Pay-Per-View - The Sun - ProQuest Archiver

A Genetics Pioneer Who Mapped the Inner World | Article from The …  -  Jul 24, 2008
...(It was cured with sulfanilamide, which had just arrived in the medical armamentarium). After college and medical school, both shortened by World War II, ... Pay-Per-View - Washington Post - HighBeam Research

Science And Salvation; EO Wilson Hopes Christians Will Join in …  -  Sep 20, 2006
He was on his own, with "no high- technology instruments, only a hand lens, forceps, specimen vials, notebooks, quinine, sulfanilamide, youth, desire, ... Pay-Per-View - Washington Post - HighBeam Research

A tragic lesson  -  Aug 26, 2007
No one tested the drug for safety, and in the fall of that year shipments of "Elixir Sulfanilamide" went out across the country. ... Boston Globe

Roy B. Morgan Advocacy Group ...  -  Jun 10, 2008
While a student, he published in a scientific journal his research on the so-called "miracle drug" sulfanilamide in 1938, just three years after its ... Pay-Per-View - Washington Post - ProQuest Archiver

THE DEMON UNDER THE MICROSCOPE  -  Oct 14, 2006
While there, he experimented with dyes as antibiotics and discovered that a dye component, sulfanilamide, killed strep and tuberculosis bacteria. ... Free with registration - Science News - AccessMyLibrary.com

Increased Extravasation of Macromolecules in Skeletal Muscles of the ...  -  Jan 25, 2005
1% sulfanilamide, 0.1% N-(1-napthyl)-ethylenediamine dihydrochloride, and 5% H 3 PO 4 ] for 10 minutes at room temperature to form a purple-azo product. ... Nature.com

Translational Toxicology and the Work of the Predictive Safety...  -  Nov 3, 2008
1 Not until the sulfanilamide disaster of 1937, the 1938 US Federal Food, Drug and Cosmetic Act, and the Nuremberg Code did animals become central to the ... Nature.com

Flaws in drug agency put consumer at risk ; Critics of FDA cite...  -  Feb 20, 2005
1938 The FDA is established when Congress enacts the Food, Drug and Cosmetic Act after 107 people are killed by elixir of sulfanilamide, a drug used to ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

Flu Hits Epidemic Levels in Moscow  -  Jun 3, 2008
..."Neither antibiotics nor sulfanilamide preparations work against the flu virus," the source said. "The unnecessary use of antibiotics leads to allergies, ... Moscow News

Flu Hits Epidemic Levels in Moscow  -  Mar 6, 2008
..."Neither antibiotics nor sulfanilamide preparations work against the flu virus," the source said. "The unnecessary use of antibiotics leads to allergies, ... Moscow News

TOP 10 NORTHWEST  -  Dec 31, 2006
..."Precisely researched and cleanly written, Hager's new book traces the discovery, rise and ultimate fall of sulfanilamide, the first synthetic antibiotic ... Pay-Per-View - The Oregonian - Factiva, from Dow Jones

SULFITES, SULFA, SULFUR ALL DIFFERENT  -  Nov 17, 2005
The sulfa drugs -- sulfanilamide, sulfathiazole, sulfadiazine and literally thousands of others -- are a class of organic (carbon- containing) chemical ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

How Safe Are Imported Foods?  -  May 23, 2007
The drug, elixir of sulfanilamide, contained a new and untested solvent, diethylene glycol, now known to be very toxic. Over one hundred people died after ... prospect.org

RESEARCHERS KEEP LOOKING FOR NEW ARTIFICIAL SWEETENERS …  -  Aug 21, 2005
He traced the sweetness back to a two-ringed chemical called benzoic acid sulfanilamide. Fully 300 times sweeter than sugar, it is indigestible by the body, ... $2.95 - St. Paul Pioneer Press - NewsBank

The story of sulfa drugs might make you want to run for the soap  -  Sep 24, 2006
Precisely researched and cleanly written, Hager's new book traces the discovery, rise and ultimate fall of sulfanilamide, the first synthetic antibiotic --a ... Pay-Per-View - The Oregonian - Factiva, from Dow Jones

CONGRESS WORKING FOR DRUG SAFETY  -  May 6, 2008
1937: Diethylene glycol in elixir sulfanilamide (prompted 1938 Food, Drug and Cosmetic Act, including the requirement that the FDA review drugs before they ... Pay-Per-View - The Sun - ProQuest Archiver

DR. ALBERT KURLAND  -  Dec 9, 2008
However, there were very few cases of shock, and the use of sulfanilamide, which all soldiers carried, was of immeasurable help in cutting down our ... Pay-Per-View - The Sun - ProQuest Archiver

Regulatory folly vs. judicial whimsy.(COMMENTARY)  -  Aug 14, 2007
In 1938, Congress enacted the Federal Food, Drug, and Cosmetic Act as an answer to more than 100 deaths from ingesting Elixir Sulfanilamide, which had been ... $4.95 - Washington Times - ECNext

Ancient advice remains valid today vekat EMPTOR" is a caution that …  -  May 13, 2006
One new medicine, a chemical compound called "sulfanilamide," killed more than 100 Americans in 1937 Some chemist came up with a formula back then trying to ... Free-Lance Star - Google News Archive

ADVANCING THE ISSUE: SEEKING SUGAR'S SUCCESSOR …  -  Aug 16, 2005
He traced the sweetness back to a two-ringed chemical called benzoic acid sulfanilamide. Fully 300 times sweeter than sugar, it is indigestible by the body, ... Pay-Per-View - Daily Press - ProQuest Archiver

100 years of safer food and drugs for FDA  -  Dec 9, 2006
One of the worst cases of a dangerous drug that lay beyond the reach of the act was the SE Massengill Company's elixir of the wonder drug sulfanilamide, ... Pay-Per-View - Fresno Bee - Factiva, from Dow Jones

ë?™ì•„사ì?´ì–¸ìŠ¤ì™€ 함께 과학ì?„ ì¦?기세요.  -  Feb 7, 2005
...따�서 많� 제약회사들� � 약품� 근본 성분� 설파� 아마�드(Sulfanilamide)를 알약형태로 주로 �산했습니다. 1937년 마센질 (Massengill)��는 제약회사� ... �아사�언스

FDA Warning: DEG-Contaminated Glycerin  -  May 8, 2007
Cosmetic Act to regulate drug safety was enacted after more than 100 US deaths in 1937 were linked to the use of DEG-contaminated sulfanilamide elixir. ... Medscape

The evolution of FDA's role in ensuring product quality: the quality...  -  Jul 1, 2007
It was not until the sulfanilamide elixir disaster that killed 107 people, many of them children, 31 years later in 1937 that Congress moved toward ... $9.94 - Pharmaceutical Technology - Alacra Store

Glycerin Contaminated with Diethylene Glycol (DEG) Remains a Potential...  -  May 6, 2007
In 1937, more than 100 people died in the United States after ingesting DEG-contaminated Elixir Sulfanilamide, a drug used to treat infections. ... HealthNewsDigest.com

Biologics oversight challenges federal regulators: efforts to ensure...  -  Aug 1, 2006
Drug, and Cosmetic Act of 1938 after more than 100 people, including many children, died in 1937 from a poisonous ingredient in Elixir Sulfanilamide. ... Free with registration - Biopharm International - AccessMyLibrary.com

Just how much is safe food worth?  -  Feb 24, 2008
In 1937, elixir of sulfanilamide containing poisonous diethylene glycol (basically antifreeze) killed 107 people including many children. ... Anderson Independent Mail

A new era in drug regulation?(at law)  -  May 1, 2005
This philosophy emerged after drug disasters such as those involving elixer sulfanilamide and thalidomide revealed the harm that could come from inadequate ... Free with registration - Hastings Center Report - AccessMyLibrary.com

Nigeria: My Pikin - Tragedy of a Killer Mixture  -  Dec 6, 2008
...destroyer of life is traceable to 1937 during the Elixir Sulfanilamide calamity in the USA where 107 people were reported to have died after taking the ... AllAfrica.com

StarFish Heating & Stirring Workstation Benefits Academic  -  Feb 20, 2007
In particular, a synthesis of sulfanilamide relied on the use of a multi-place water bath for reflux. This system did not prove to be synthetically reliable ... Laboratory Network

Inhibition of Nitric Oxide Can Ameliorate Apoptosis and Modulate...  -  Mar 20, 2005
An aliquot of 100 l collected culture medium were incubated with 50 l of 0.1% sulfanilamide in 5% phosphoric acid and 50 l of 0.1% N-1-naphthyl- ... RedOrbit

Sulfonamides (Vaginal).(Anti-infective agent overview)(Drug overview)  -  Aug 1, 2006
For sulfanilamide For (vaginal cream) dosage form: For bacterial infections: Adults and teenagers -- One applicatorful (approximately 6 grams) inserted into ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Avoid Antibiotic .  -  Dec 14, 2006
Then came the explosive news of sulfanilamide, and the start of the real revolution hi medi cine. I remember the astonish ment when the first cases of ... Sanborn Weekly Journal - Google News Archive

Proposal issued to revoke, modify and establish tolerances.(FIFRA)( …  -  Sep 25, 2006
...to read: tolerances established for combined residues of asulam (methyl sulfanilylcarbamate) and its metabolite containing the sulfanilamide moiety ... Free with registration - Pesticide & Toxic Chemical News - AccessMyLibrary.com

Article | The American Prospect  -  May 27, 2005
In the late 1930s, 107 Americans died after drinking "Elixir of Sulfanilamide," a chemical relative of a radiator antifreeze marketed as a medicine. ... prospect.org

Cleaning--where are we now and where are we headed with important …  -  Aug 1, 2007
The first major problem the FDA and the nation faced together was to contend with the elixir of sulfanilamide--ethylene glycol--contamination which caused ... Free with registration - Journal of Validation Technology - AccessMyLibrary.com

Salute Of Remembrance' For Former Air Station .  -  Apr 4, 2007
The one thing I do remember, believe me, is the face of a Navy doctor who shared a new drug, sulfanilamide, with me when I was afflicted with mastoiditis ... Arlington Times - Google News Archive

Emission of nitrogen dioxide from butane gas heaters and stoves...  -  Mar 1, 2005
The Griess reagent (2% sulfanilamide and 0.01% N-1-naphthylethylenediamine dihydrochloride w/v in 0.150:1 v/v, 37% HCl:water) was used for the determination ... Free with registration - American Journal of Applied Sciences - AccessMyLibrary.com

Cutting Sugar in Foods Not an Easy Task for Researchers  -  Aug 25, 2005
He traced the sweetness back to a two-ringed chemical called benzoic acid sulfanilamide. Fully 300 times sweeter than sugar, it is indigestible by the body, ... RedOrbit

Sulfonamides (Vaginal).  -  Feb 1, 2006
For sulfanilamide For (vaginal cream) dosage form: For bacterial infections: Adults and teenagers -- One applicatorful (approximately 6 grams) inserted into ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Cisplatin-induced renal injury  -  Aug 1, 2005
The absorbance of chromophore formed during diazotization of nitrite with sulfanilamide and subsequent coupling with naphthalene diamine was read at 546 nm. ... Free with registration - Phytomedicine: International Journal of... - AccessMyLibrary.com

Glutamate-induced cell death in neuronal HT22 cells is attenuated by ...  -  Apr 1, 2007
NO was determined as nitrite with the "Griess" reaction with 1% sulfanilamide, 0.1% N-(1-naphthyl) ethylene diamine in 2% phosphoric acid. ... Free with registration - Phytomedicine: International Journal of... - AccessMyLibrary.com

This Report Reveals the Findings of the Pharmaceutical Raw Materials ...  -  Mar 9, 2008
...endocrine products, basic vitamins, sulfanilamide medicine, salicylate, glucose and alkaloids. However, hematic products are not included. ... Ad-Hoc-News - Ad-Hoc-News (Pressemitteilung)

Featured Report: Enhanced Physician Access to FDA Data (A-05)  -  Feb 20, 2005
In 1937, elixir of sulfanilamide, which contained the poisonous solvent diethylene glycol, led to the death of 107 persons, including many children. ... American Medical News

Clinical Trial Animal Testing: Progress Or Pain?  -  Nov 11, 2008
That practice changed drastically when more than 100 people died in 1937 after taking a drug called Elixer of Sulfanilamide. ... TheDenverChannel.com

Rhabdomyolysis due to hair dye poisoning: An emerging threat.(Case …  -  Oct 1, 2007
An epidemic of diethylene glycol (DEG)-induced ARF was first reported in the 1930s amongst children in the United States who consumed sulfanilamide elixir ... Free with registration - Indian Journal of Critical Care Medicine - AccessMyLibrary.com

Ambient levels of air pollution induce goblet-cell hyperplasia in...  -  Dec 1, 2007
The nitrite produced during sampling was determined colorimetrically by reacting the exposed absorbing reagent with sulfanilamide and ... Free with registration - Environmental Health Perspectives - AccessMyLibrary.com

Spitz, Vivien. Doctors from Hell: The Horrific Account of Nazi...  -  May 15, 2005
There were sulfanilamide experiments conducted on Polish Catholic priests in Dachau, and seawater experiments on Gypsies. Spitz also reports on the ... Free with registration - Booklist - AccessMyLibrary.com

Carbonic anhydrase facilitates CO2 and NH3 transport across the …  -  Oct 1, 2005
Tissue was perfused with either control saline or saline containing the CA inhibitors quaternary ammonium sulfanilamide (QAS) or acetazolamide (Az). ... AJP-Regul Integr Comp Physiology...

CLINICAL TRIALS: ANIMAL TESTING: PROGRESS OR PAIN?  -  Nov 20, 2008
That practice changed drastically when more than 100 people died in 1937 after taking a drug called Elixer of Sulfanilamide. The incident encouraged the ... WPTV

Deaths led US to require proof of drugs' safety .  -  Oct 6, 2005
An antibacterial syrup called Elixir Sulfanilamide killed at least . 75 people, some of them young children who had been suffering from nothing more serious ... The Day - Google News Archive

To test or not to test? The glycerin debate  -  Jun 14, 2007
And in 1937, more than 100 people died in the United States after taking DEG-contaminated Elixir Sulfanilamide, a drug used to treat infections. ... In-PharmaTechnologist.com

Lavender Magazine - Minnesota's GLBT Magazine - Gay, Lesbian, …  -  Mar 9, 2008
In 1937, it was discovered that the antibacterial sulfanilamide, highly successful in powders and pills, would dissolve in ethylene glycol. ... Lavender Magazine

Nitrite assay kit.(PRODUCTS: Biochemicals & Kits)  -  May 1, 2006
The nitrite that is formed reacts with sulfanilamide and N-(1-naphthyl)-ethylenediamine dihydrochloride instantaneously to give a red-violet diazo dye. ... Free with registration - Bioscience Technology - AccessMyLibrary.com

Brand Names/Synonyms:
Sulfanilamide is also known by the following brand names and/or synonyms1162 F; A-349; AVC; Albexan; Albosal; Ambeside; Antistrept; Astreptine; Astrocid; Avc; Bacteramid; Bactesid; Collomide; Colsulanyde; Copticide; Deseptyl; Desseptyl; Dipron; Ergaseptine; Erysipan; Estreptocida; Exoseptoplix; F 1162; Fourneau 1162; Gerison; Gombardol; HSDB 223; Infepan; Lusil; Lysococcine; NSC 7618; Neococcyl; Orgaseptine; P-Aminobenzenesulfamide; P-Aminobenzenesulfonamide; P-Aminobenzenesulfonylamide; P-Aminobenzensulfonamide; P-Aminophenylsulfonamide; P-Anilinesulfonamide; P-Sulfamidoaniline; P-Sulfamoylaniline; PABS; Prontalbin; Prontosil Album; Prontosil I; Prontosil White; Prontylin; Pronzin Album; Proseptal; Proseptine; Proseptol; Pysococcine; Rubiazol A; Sanamid; Septamide Album; Septanilam; Septinal; Septolix; Septoplex; Septoplix; Solfanilamide [Dcit]; Stopton Album; Stramid; Strepamide; Strepsan; Streptagol; Streptamid; Streptamin; Streptasol; Streptocid; Streptocid Album; Streptocide; Streptocide White; Streptocidum; Streptoclase; Streptocom; Streptol; Strepton; Streptopan; Streptosil; Streptozol; Streptozone; Streptrocide; Sulfamidyl; Sulfamine; Sulfana; Sulfanalone; Sulfanidyl; Sulfanil; Sulfanilamide; Sulfanilamide Vaginal Cream; Sulfanilimidic Acid; Sulfocidin; Sulfocidine; Sulfonamide; Sulfonamide P; Sulfonylamide; Sulphanilamide; Sulphanilamide Extra Pure; Sulphanilamide Gr; Sulphonamide; Therapol; Tolder; White Streptocide

Drug Category:
Sulfanilamide is categorized under the following by the FDA: Anti-bacterial Agents; Homeopathic Agents; ATC:J01EB06

Dosage Forms:
LIQUID; PELLET; TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
4-aminobenzenesulfonamide





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