Taxol

This page contains recent news articles, when available, and an overview of Taxol but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Taxol
(when available)

Pharmacology and use:
Paclitaxel is a taxoid antineoplastic agent indicated as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast cancer. Paclitaxel is a novel antimicrotubule agent that promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization. This stability results in the inhibition of the normal dynamic reorganization of the microtubule network that is essential for vital interphase and mitotic cellular functions. In addition, paclitaxel induces abnormal arrays or "bundles" of microtubules throughout the cell cycle and multiple asters of microtubules during mitosis. For the treatment of breast and ovarian cancer

Mechanism Of Action:
Paclitaxel stabilizes microtubules by preventing depolymerization. Specifically it binds to tubulin. This stability results in the inhibition of the normal dynamic reorganization of the microtubule network that is essential for vital interphase and mitotic cellular functions.

News Articles on Paclitaxel

Follow-up Presented of Nexavar® plus Taxol® Study for Treatment of Advanced ...  -  ‎Dec 17, 2009‎
Researchers involved in an international randomized Phase IIB study have reported that the combination of Nexavar® (sorafenib) and Taxol® (paclitaxel) ... Cancer Consultants

Addition of Neratinib to Taxol in Women with Metastatic Breast Cancer Shows ...  -  ‎Dec 19, 2009‎
Researchers working in an extensive international Phase I/II trial of the treatment have reported that the addition of Neratinib to Taxol has managed to ... TopNews New Zealand

How local spices halt breast cancer spread  -  ‎Dec 10, 2009‎
The mice then were divided into four groups: one got no treatment, one got curcumin, one got the cancer drug Taxol and the fourth group got curcumin plus ... The Guardian - Nigeria

Big Buy: ADVENTRX's NDA and Financing News (AMEX:ANX)  -  ‎Jan 4, 2010‎
Prior to generic entrants in 2001 Taxol sold $1.8 billion dollars, Abraxane sold $335 million dollars in 2008- nearly 40% of the taxane market share in this ... Small Cap Network

Nobel Laureate Explores Links Between Climate Change, Biodiversity  -  ‎Dec 18, 2009‎
And in the bark of this runted, useless tree, they found a wonderful molecule called taxol, which, in early trials, was shown to be the most effective agent ... NewsHour

Millman's Blog: Counting Down The Chemo Treatments  -  ‎Dec 21, 2009‎
I continue to feel better on the Taxol than I did on the 'red devil' treatment. I will say however, I am tired. Before my infusion every Monday the nurses ... KIROtv.com

Garden to cultivate medicinal potential of plants  -  ‎Jan 4, 2010‎
That means a chemotherapy drug such as Taxol is still made using clippings from Pacific yew trees, she said. “Plants are a chemical factory, and each plant ... Lawrence Journal World

Jackson Lab Studies Genetic Link To Chemo Reactions  -  ‎Dec 24, 2009‎
Imagine if they could know in advance, oh, this is going to work beautifully with Jenifer, she's not allergic to taxol. Oh, let's not give it to Debbie ... MPBN News

Bristol-Myers Cuts 2009 Outlook - Analyst Blog  -  ‎Dec 24, 2009‎
Generic competition has resulted in drugs such as Cefzil, Paraplatin, Glucophage, Monopril and Taxol experiencing sales declines. ... Benzinga

Pomegranate 'can combat MRSA and other superbugs'  -  ‎Dec 26, 2009‎
Taxol (paclitaxel) is a chemotherapy drug that has been in use for many years. It is extracted from yew bark and needles. The white powder is turned into a ... The Guardian

Gene Patenting Debate Continues - Round Three  -  ‎Dec 18, 2009‎
With regard to the patentability of natural products, Dr. Noonan countered that antibiotics made by bacteria and the anti-cancer drug taxol, ... Patent Docs (blog)

25 gifts making a tough 2009 a bit better for Tampa Bay area  -  ‎Dec 23, 2009‎
...discovered by USF researchers, might generate big royalties to the university like Gatorade did for UF or cancer drug Taxol did for FSU. ... Tampabay.com

Our debt to plants  -  ‎Dec 27, 2009‎
...throughout Britain are being urged to collect and save trimmings of their yew trees (Taxus baccata) for processing into the anti-cancer drug, Taxol. ... Stabroek News

MSU receives $2 million to further study diesel-producing South American fungus  -  ‎Dec 16, 2009‎
...properties can be put to use in ways that benefit humans -- such as the endophyte he discovered that naturally produces the cancer drug taxol. ... The Bozeman Daily Chronicle

research could lead to legitimate meth windfall  -  ‎Dec 12, 2009‎
Sometimes, such efforts pay off in huge ways, such as the University of Florida's inventions of Gatorade and the cancer drug Taxol, or Northwestern's ... The Missoulian

NextWave Research places “strong speculative buyâ€? rating on Access Pharmaceuticals  -  ‎Dec 18, 2009‎
Access is planning Phase II trials in combination with Taxol (paclitaxel) in recurrent ovarian cancer and liver and/or pancreatic cancer with Gemzar. ... Proactive Investors Australia

Bristol-Myers Sets Swap Offer Rate  -  ‎Dec 17, 2009‎
Generic competition has resulted in drugs such as Cefzil, Paraplatin, Glucophage, Monopril and Taxol experiencing sales declines. ... Zacks.com

Kanserli hastaya bir darbe de SGK'dan  -  ‎Dec 22, 2009‎
Tüm Eczacı İşverenler Sendikası Yönetim Kurulu Üyesi Burak Kaan Seyrekbasan, “ÖrneÄŸin, kanserli bir hasta normalde hiç para vermeden aldığı Taxol isimli ... Hürriyet

Prise de tête  -  ‎Dec 26, 2009‎
D'autant que je n'ai plus aucune chimiothérapie (Herceptin excepté) depuis un mois et que la précédente au Taxol a prouvé son inefficacité, ... Libération

Nuevo año empieza con grandes expectativas en campo médico  -  ‎Jan 3, 2010‎
...este fármaco mata a las células madre del cáncer de mama unas 100 veces más que la quimioterapia más común en la actualidad (el Taxol o paclitaxel). ... Nueva Prensa de Guayana

De l'intérêt des digressions  -  ‎Dec 12, 2009‎
Evidemment, le Dr GG eut préféré que la chimiothérapie au Taxol réponde davantage. Là, c'est un échec, on ne gagne pas à tous les coups. ... Libération

Trồng đại trà thông Ä‘á»? làm nguyên liệu dược phẩm  -  ‎Dec 14, 2009‎
Cây thông Ä‘á»? được Trung tâm trồng tại Tà Nung và Cam Ly cho hàm lượng hoạt chất taxol và 10-DAB (Deacetyl Baccatyl III) gấp 2 - 4 lần so vá»›i cây thông Ä‘á»? tá»± ... Báo Đất Việt

Gripe y células madre  -  ‎Dec 26, 2009‎
...este fármaco mata a las células madre del cáncer de mama unas 100 veces más que la quimioterapia más común en la actualidad (el Taxol o paclitaxel). ... El País (España)

利润的诱惑制è?¯ä¼?业走å?‘金字塔尖的抗肿瘤  -  ‎Dec 10, 2009‎
...ä½?于第21ä½?的泰素(Taxol)是唯一跻身销售é¢?超过10亿美元å‰?30强的抗肿瘤è?¯ã€‚而2008å¹´å…¨ç?ƒé”€å”®é¢?最高的å‰?200å??è?¯å“?总,肿瘤è?¯è¾¾åˆ°äº†23å?ªï¼Œåœ¨126å?ªé”€å”®é¢?达到10亿美元的 ... 中国高新技术产业导报

Government Health System Penalized Woman for Supporting Her Own Cancer Treatment  -  ‎Nov 11, 2009‎
The 58-year-old former NHS nurse was given Taxol, a chemotherapy drug, as part of her publicly-financed health care. But, following the advice of her ... National Center for Public Policy Research

Endangered Lam Dong red pines provide cancer treatment  -  ‎Nov 10, 2009‎
The scientists aim to extract 0.5kg of 10-DAB active element and 10g taxol from the leaves and young branches of the red pines by 2010. ... VietNamNet Bridge

Readers Say  -  ‎Oct 28, 2009‎
As a physician I am greatly disturbed by the suggestion that Taxol is equivalent to the nanoparticle albumin-bound Abraxane ("Cancer Man"). ... Forbes

Life is precious, no matter what; but it could be worse  -  ‎Nov 6, 2009‎
Twenty weeks of Adriamycin and Taxol come in with hair loss, fatigue, nausea and vomiting, sores and diarrhoea. Extra heartbeats are noted in her case and a ... Daily Nation

Party to raise funds for cancer victim  -  ‎Nov 12, 2009‎
Smalls has just finished undergoing taxol chemotherapy treatments. This week, she has started her chemotherapy radiation process. "She is in good spirits. ... The Daily News of Newburyport

Cramer's Mad Money - Agnico Eagle's Golden Disappointment (11/2/09)  -  ‎Nov 3, 2009‎
Erbitux for colorectal, head and neck cancer, Sprycel for Leukemia, Ixempra for breast cancer and Taxol for breast, lung and ovarian cancer. ... Seeking Alpha (blog)

Nikki Patrick tells of her triumph over breast cancer  -  ‎Oct 20, 2009‎
After the two-drug cocktail, I had four weekly cycles of Taxol. After that I was blasted with radiation 35 times. Now my life is nearly back to normal. ... Pittsburg Morning Sun

The Great Reaction  -  ‎Nov 12, 2009‎
It took chemists two decades to figure out how to produce the cancer drug Taxol in the lab. Before that, it had to be derived from the bark of the Pacific ... MSN Philippines News

Updated NCCN Guidelines for Breast Cancer Discourages Prophylactic Mastectomy ...  -  ‎Oct 28, 2009‎
Pfizer Inc.) / cyclophosphamide (Cytoxan(R), Bristol-Myers Squibb Company)] followed by weekly paclitaxel (Taxol(R), Bristol-Myers Squibb Company) as an ... Reuters

Going back to work with cancer  -  ‎Nov 6, 2009‎
She's thinking about another family trip in the spring, when she's scheduled to finish her weekly doses of Taxol, a chemotherapy drug. ... CharlotteObserver.com

NeoPharm, Inc. Announces Third Quarter 2009 Financial Results and Clinical ...  -  ‎Oct 26, 2009‎
...the active ingredient of Taxol, designed to evaluate the anti-tumor effect and safety/tolerability of LEP-ETU in metastatic breast cancer. ... Reuters

Vaughn v. Mississippi Baptist Medical Center  -  ‎Oct 30, 2009‎
The decedent in Sacks was being treated for lung cancer with a highly toxic drug named Taxol. Id. at 618. The treatment was administered via intravenous ... Leagle, Inc.

Breast cancer survivor helps others through clinical trial, Komen support 10-25-09  -  ‎Oct 25, 2009‎
..."My surgeon asked if I had been in pain lately, and I told him with Taxol I'm always in pain. My legs always hurt. He said, 'Your port isn't working . ... Plainview Daily Herald

OSI Pharmaceuticals, Inc. Q3 2009 Earnings Call Transcript  -  ‎Oct 21, 2009‎
We also initiated a second study in the third quarter, a phase 1/2 trial evaluating OSI 906 in combination with Taxol, primarily patients with recurrent ... Seeking Alpha (blog)

NeuroVive doses last patient in clinical trial of cremophor®- free ...  -  ‎Nov 5, 2009‎
...will provide a safer alternative to patients, similar to the introduction of cremophor-free Paclitaxel (Taxol®) and Propofol (Diprivan®) products. ... PipelineReview.com (press release)

Not so pretty in pink  -  ‎Oct 31, 2009‎
Taxol was found in the bark of the Pacific yew tree and targets the ability of cancer cells to reproduce. An unfortunate side effect is the loss of hair. ... WA today

A Cure for Cancer?  -  ‎Nov 4, 2009‎
But BMY also has Erbitux for colorectal, head and neck cancer, Sprycel for Leukemia, Ixempra for breast cancer and Taxol for breast, lung and ovarian cancer ... CNBC

Kankermedicijn taxol is te verbeteren  -  ‎Oct 30, 2009‎
Het remmen van twee celdelingseiwitten verhoogt de gevoeligheid van kankercellen voor het veelgebruikte kankermedicijn taxol. Onderzoekers van het UMC ... Zorgkrant

Tổng hợp hoạt chất chữa ung thư từ thông Ä‘á»? Lâm Ä?ồng  -  ‎Nov 9, 2009‎
...“Tuy cùng má»™t quần thể nhưng những cây thông Ä‘á»? tá»± nhiên có hàm lượng 10 – DAB và taxol khác xa nhau, hàm lượng các hoạt chất này mang tính di truyá»?n nên ... Tiền Phong Online

Die Eibe: Vom Giftpfeil zum Medikament  -  ‎Nov 4, 2009‎
Bedeutung erlangt hat heute die asiatische Eibe (Taxus brevifolia), deren Rinde das Zytostatikum Taxol enthält. Da Krebszellen schneller wachsen als normale ... suedkurier.de

竹溪县å??八里长峡四å?ƒäº©çº¢è±†æ?‰ç¡•果累累  -  ‎Oct 23, 2009‎
...红豆æ?‰çš„æ??å?–物(TAXOL PACLI TAXEL)紫æ?‰é†‡å…·æœ‰ç‹¬ç‰¹çš„æŠ—癌机ç?†ï¼Œç¾Žå›½å›½ç«‹è‚¿ç˜¤ç ”究所所长BRODERå?šå£«ç§°ç´«æ?‰é†‡æ˜¯ç»§é˜¿éœ‰ç´ ã€?顺铂以å?Žï¼Œå??五年æ?¥è¢«å…¨ç?ƒè®¤å…¬ä¸ºæ˜¯å¯¹å¤šç§?癌症 ... 新浪网

Au petit poil  -  ‎Oct 27, 2009‎
Oui, le Taxol est moins alopéciant que le Taxotère, d'abord parce que le dosage du premier est moindre en chimio hebdomadaire que l'arrosage bazooka du ... Libération

Tumore polmonare non a piccole cellule, avanzato e non-operabile: la ...  -  ‎Oct 29, 2009‎
...randomizzati di fase II ( n=99 ) e fase III ( n=878 ) sull'uso di Bevacizumab ( Avastin ) più Carboplatino ( Paraplatin ) e Paclitaxel ( Taxol ). ... XagenaSalute

A TeremtÅ‘ patikája  -  ‎Oct 29, 2009‎
...codein a máktejbõl, az acetilszalicilsav, vagyis az aszpirin a fehérfûz kérgébõl, a kemoterápiás szerként használt taxol pedig a tiszafából nyerhetõ ki. ... Hetek

Thuần hóa thông Ä‘á»? thành cây trồng nông nghiệp  -  ‎Oct 21, 2009‎
Theo các tài liệu khoa há»?c, thông Ä‘á»? là cây lâm nghiệp làm dược liệu (quý hiếm) chiết tách hoạt chất taxol và taxotere để Ä‘iá»?u chế thuốc chữa bệnh ung thư. ... Kinh tế Nông thôn

Taxol useless in treating breast cancer  -  Oct 11, 2007
BEIJING, Oct. 11 (Xinhuanet) -- Taxol, a widely used chemotherapy drug, is useless in treating the most common form of breast cancer and helps far fewer ... 新�网

Weekly Doses of Taxol Prolonged Lives of Breast Cancer Patients  -  Apr 16, 2008
By Amanda Gardner. WEDNESDAY, April 16 (HealthDay News) -- Women who take the drug Taxol weekly after receiving chemotherapy for 12 weeks live longer and ... Washington Post

New Form of Breast Cancer Drug Approved  -  Jan 8, 2005
Taxol, which is sold by Bristol-Myers Squibb, is also available in generic forms. Before the generic competition started, sales had reached more than $1 ... New York Times

Major Breakthrough in Treating Ovarian Cancer, Doctors Report  -  Jan 4, 2006
Half the women in the study got standard intravenous chemotherapy with Taxol and cisplatin. The others got IV Taxol, then abdominal infusions of cisplatin ... FOXNews

Hope, at $4,200 a Dose  -  Oct 1, 2006
Both Abraxane and Taxol can kill white blood cells, leaving patients open to ... Taxol causes more damage to white blood cells, while Abraxane causes more ... New York Times

IN BRIEF / WASHINGTON, DC; Nicotine May Weaken Effect of Cancer …  -  Apr 3, 2006
Nicotine can prevent chemotherapy drugs such as Taxol from killing lung cancer ... The researchers tested the drugs gemcitabine, cisplatin and Taxol on ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

New weapon to beat drug resistance  -  Aug 20, 2008
The study focused on a way of boosting Taxol levels within ovarian cancer cells ... "Taxol works pretty well in the beginning - 70 or 80% of patients have a ... Independent Online

Article: Taxol of limited use, study finds - The Record (Bergen...  -  Oct 11, 2007
Taxol of limited use, study finds ... find The Record (Bergen County, NJ) articles. MARILYNN MARCHIONE, THE ASSOCIATED PRESS The Record (Bergen County, ... Pay-Per-View - The Record - HighBeam Research

A Nano Drug's Giant Promise  -  Apr 11, 2005
The drug is a reengineered form of Taxol, a popular chemotherapy ... Although Taxol is effective, it has such high toxicity that its label warns of "severe ... BusinessWeek

Drug prevents male fertility loss after chemotherapy  -  Jun 20, 2006
A single dose of Taxol caused significant testicular weight loss compared with the control group, but the testes of mice given Taxol in combination with ... New Scientist

Sonus Shares Fall After Cancer Drug Fails in Trial  -  Sep 24, 2007
...s Taxol. Sonus, which has no marketed products, uses the same active ... The market for Taxol, generics and a related drug is $3.5 billion a year, ... Bloomberg

Taxol, a cancer aid, may have new benefit.  -  Nov 1, 2005
Nov. 1--DURHAM -- Taxol, an extract from the Pacific yew tree found some 40 years ago by Durham scientist Mansukh Wani and his colleague Monroe Wall, ... Free with registration - Herald Sun - AccessMyLibrary.com

Bristol-Myers settles Plavix case with states  -  Dec 23, 2008
The Plavix settlement triggered Bristol's notification obligations under the Buspar and Taxol court orders. (Reporting by Toni Clarke; editing by John ... Reuters

Bricks or Professors? A University's Choice  -  Dec 6, 2006
So when a chemistry professor at Florida State, Robert A. Holton, made a series of breakthroughs over the past 20 years involving the anticancer drug Taxol, ... New York Times

Bristol Avoids Trial Over Taxol Price With Settlement  -  Jul 18, 2007
By Cary O'Reilly. July 18 (Bloomberg) -- Bristol-Myers Squibb Co. agreed to settle a class-action lawsuit over prices the company charged for its Taxol ... Bloomberg

Time runs out in cancer drug row  -  Jan 28, 2008
Ms Mills was being treated with the drug Taxol by the South Tees NHS Trust but claimed it ... They have now told me Taxol is not working, nor would Avastin, ... BBC News

GPC Biotech starts phase II trial on Satraplatin to treat lung cancer  -  Dec 9, 2005
MARTINSRIED, Germany (AFX) - GPC Biotech AG said it has started a phase II trial to evaluate the Satraplatin drug, in combination with Taxol, as first-line ... Forbes

Taxol found ineffective in some breast cancer .  -  Oct 11, 2007
The widely used chemotherapy drug Taxol does not work for the most common ... want to make sure, these data are correct before withholding it taxol from ... St. Petersburg Times - Google News Archive

New breast cancer treatment 'can double life expectancy'  -  Mar 23, 2006
The patients received either the chemotherapy drug Taxol or a combination of Taxol and Avastin, which is licensed for advanced bowel cancer. ... Telegraph.co.uk

Taxol may be ineffective for many cancer patients | Article from...  -  Oct 11, 2007
Taxol may be ineffective for many cancer patients ... find Deseret News (Salt Lake City) articles. The widely used chemotherapy drug Taxol does not work for ... Pay-Per-View - Deseret News - HighBeam Research

FDA Approves New Breast Cancer Drugs  -  Jan 11, 2005
By binding the active ingredient (the breast cancer drug Taxol) to microscopic protein molecules, these drugs eliminate the need for using toxic solvents to ... FOXNews

US chemists synthesize promising anti-cancer product_English_Xinhua  -  Aug 21, 2008
...researchers demonstrated that largazole could impede breast cancer cell growth better than the anti-tumor drug Taxol without causing side effects on ... 新�网

Taxol pioneer finds diesel-producing fungus  -  Nov 4, 2008
The discovery of taxol, a compound found in the Pacific yew tree, turned out to be a real life-saver for some women with breast cancer. ... nwsource.com

Professor sues FSU over chemistry school.  -  Nov 9, 2005
Taxol generated about $350-million in royalties for Holton and FSU. Holton got about $140-million of ... FSU got about $210-million of the Taxol royalties. ... Free with registration - St. Petersburg Times - AccessMyLibrary.com

Lab disaster may lead to new cancer drug  -  Feb 4, 2007
The compound works in much the same way as the taxane drugs, including Taxol, which were originally derived from Pacific yew trees. ... Reuters

Jamaican cancer drug found - Scientific findings surround endemic...  -  Dec 12, 2006
The plants were tested in a semi-purified state individually and as a 1:4 combination with Taxol and reportedly killed cancer cells at the same rate as the ... Jamaica Gleaner

How curry can help keep cancer at bay  -  Oct 15, 2005
The rest were given a common chemotherapy drug called Taxol, ... By contrast, none of those given curcumin and Taxol developed clearly visible tumours. ... Daily Mail

Avastin, Taxol combo dramatically increases breast cancer therapy …  -  Dec 28, 2007
London, December 28 : Indiana University researchers have successfully concluded the first ever trial involving the inclusion of an antiangiogenic agent ... thecheers.org

Figure 4 : The APC/C maintains the spindle assembly checkpoint by …  -  Nov 9, 2008
...(a–c) Taxol-arrested cells (a) or taxol-arrested cells treated with MG132 for 2 h (b) or taxol-arrested cells treated with MG132 and ZM447439 for 2 h (c) ... Nature.com

Article: Taxol, a cancer aid, may have new benefit. - Herald-Sun...  -  Nov 1, 2005
Taxol, a cancer aid, may have new benefit. ... find Herald-Sun (Durham, NC) articles. Byline: Jim Shamp Nov. 1--DURHAM -- Taxol, an extract from the Pacific ... Pay-Per-View - Herald Sun - HighBeam Research

Genentech submits data for breast cancer drug combo  -  Aug 24, 2007
The submission marks the beginning of the US Food and Drug Administration's six-month review of Avastin plus Paclitaxel, known as Taxol, Genentech said in a ... Reuters

Student Research Aims to Boost Production of Cancer Drug Taxol  -  Apr 4, 2008
Newswise — Two sophomores at the University of Massachusetts Amherst are working on a new method to boost production of the world's best-selling ... newswise.com

Wider funding for cancer drug  -  Aug 31, 2006
Drug-buying agency Pharmac says the drug Taxol will be funded for 550 women with a wide ... But Pharmac says Taxol will treat a much wider range of cancers, ... TVNZ

Sonus starts key trial for breast cancer drug  -  Sep 29, 2005
The established drug Taxol is approved for dosing at three-week intervals but frequently is given on a weekly basis, he said. That intensity carries with it ... Seattle Times

NHS threat to halt care for cancer patient  -  Dec 16, 2007
Mills, a mother of two, who lives near Stokesley in North Yorkshire, is being treated with the drug Taxol, which is available on the NHS, but believes that ... Times Online

Cypher & Taxol Drug Eluting Stents placed acutely post MI  -  Sep 19, 2006
They study the two most popular DESs, unfortunately in two separated studies, not allowing accurate direct comparison between them. ... Gerson Lehrman Group

Putting stock in bonds  -  Sep 21, 2008
Janine Feliciano, who began her nursing career in oncology 14 years ago, remembers when the chemotherapy drug, Taxol, was given to patients in a hospital ... Atlanta Journal Constitution

Article: FEWER WOMEN NEED TAXOL STUDY FINDS IT DOES NOT …  -  Oct 11, 2007
FEWER WOMEN NEED TAXOL STUDY FINDS IT DOES NOT WORK FOR MOST.(News)(Report) ... find The Cincinnati Post (Cincinnati, OH) articles. Pay-Per-View - Cincinnati Post - HighBeam Research

Taxol(r) (paclitaxel) Approved in Europe for the Adjuvant Treatment...  -  Mar 17, 2005
Bristol-Myers Squibb announces the approval of Taxol(r) (paclitaxel) for the treatment of early stage node-positive breast cancer following standard ... Free with registration - PR Newswire Europe - AccessMyLibrary.com

Tweaking Taxol points way to a greener, more productive future  -  Mar 24, 2006
As the effective cancer-treatment drug Taxol enters its next generation, Michigan State University announces discoveries which point to both environmentally ... eurekalert.org

… NOTED: Barr gets FDA's blessing for generic Taxol; Biovail founder...  -  Mar 13, 2008
...> Barr Pharmaceuticals got the FDA's final nod for its generic version of the Bristol-Myers Squibb cancer med Taxol. Report ... FiercePharma

Cancer researcher Susan Horwitz wins Alpert prize for Taxol work  -  Jun 23, 2005
Susan Band Horwitz, Ph D, the Falkenstein Professor of Cancer Research and Co-Chair of the Department of Molecular Pharmacology at the Albert Einstein ... Medical News Today - Medical News Today (press release)

Tweaking Taxol Points Way To A Greener, More Productive Future  -  Mar 28, 2006
As the effective cancer-treatment drug Taxol enters its next generation, Michigan State University announces discoveries which point to both environmentally ... Medical News Today - Medical News Today (press release)

New Research Questions Taxol's Efficacy for Common Breast Cancer  -  Oct 15, 2007
After enduring four grueling rounds of Taxol during my chemotherapy treatments ... Using modern genetic tools, the study re-examined early Taxol studies and ... HealthCentral.com

Cancer researcher Susan Horwitz wins Alpert prize for Taxol work  -  Jun 26, 2005
Susan Band Horwitz, Ph D, the Falkenstein Professor of Cancer Research and Co-Chair of the Department of Molecular Pharmacology at the Albert Einstein ... i-newswire.com

Taxol only used in some cases of triple-negative?  -  Aug 18, 2008
Question from Kelly: Why is it that some triple-negatives receive Taxol during chemotherapy and some patients do not? Answers —George Sledge, MD: In my ... Breastcancer.org

Fewer Women Need Chemo Drug Taxol; Study Finds It Doesn't Work For …  -  Oct 11, 2007
...widely used chemotherapy drug Taxol does not work for the most common form of ... In the study, Taxol did the most good for women who had overactive her-2 ... Herald-Journal - Google News Archive

Breast cancer drug funded  -  Sep 1, 2006
Drug funding agency Pharmac has decided to fund the drug Taxol for the treatment of early-stage breast cancers at a cost of $12.5 million over five years. ... New Zealand Herald

Treating tumours Golden slingshot  -  Nov 6, 2008
...stage IIIc) and a very aggressive chemotherapy treatment (intraperitoneal cisplatin and taxol and intravenus taxol), I am in my first remission. ... economist.com

Victoria University makes cancer breakthrough  -  May 11, 2005
Dr Northcote said Peloruside shares a "molecular target" with Taxol, a cancer therapy agent developed for use against ovarian and breast cancer. ... New Zealand Herald

Chemo Regimen FAQs: AC + Taxol/Taxotere chemotherapy (ACT, TAC)  -  Jul 17, 2007
Q. I've just found out I have to have chemotherapy. The doctor said it's AC and Taxol [or Taxotere]. What does that mean, exactly? ... HealthCentral.com

Effective biosynthetic alternative to Taxol production discovered  -  May 3, 2006
By Gregory Roumeliotis, 03-May-2006. Researchers at Michigan State University have found that second-generation taxols, which currently rely on assembly by ... In-PharmaTechnologist.com

CANCER DRUG DEVELOPER BATTLES FSU RESEARCH CENTER AT …  -  Dec 19, 2005
Holton, 61, did not invent Taxol. It is a naturally occurring compound found in the bark ... Despite his Taxol wealth, Holton still works at Florida State, ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

New method to overcome multiple drug resistant diseases developed by ...  -  Aug 18, 2008
That change in physical properties effectively cloaks the arginine-Taxol ... But after getting into the cell, the arginine-Taxol complex still has to break ... eurekalert.org

… By Drug, Cancer Study Says .Research Suggests That Taxol Isn't As ...  -  Oct 11, 2007
...used chemo drug Taxol does not work for the most common form of breast cancer ... In the study, Taxol did the most good for women who had overactive her-2 ... Eugene Register-Guard - Google News Archive

Psychological help aids cancer patients  -  Jan 29, 2008
Patients who exercised received a higher dose of the chemotherapy drug Taxol, possibly improving their overall treatment. United Press International

… Comparative Effectiveness of XYOTAX(TM) to Taxol(R) in Women With ...  -  Dec 6, 2005
XYOTAX (paclitaxel poliglumex) is a biologically-enhanced chemotherapeutic that links paclitaxel, the active ingredient in Taxol(R), to a biodegradable ... Free with registration - PR Newswire - AccessMyLibrary.com

Mother Nature's pharmacy  -  Mar 5, 2006
Horwitz discovered that Taxol stabilizes microtubules, preventing them from ... It is now known that Taxol disturbs cellular growth at various stages ... Pay-Per-View - Jerusalem Post - ProQuest Archiver

… Results From EntreMed's Panzem(R) NCD and Taxol(R) Breast Cancer …  -  Jun 6, 2007
ROCKVILLE, Md., June 6 /PRNewswire-FirstCall/ -- EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics primarily ... Genetic Engineering News - Genetic Engineering News (press release)

Taxol .  -  Oct 11, 2007
Taxol did not significantly help women whose tumors were her-2 negative and were ... Researchers tested adding paclitaxel. sold as Taxol by New York-based ... Lakeland Ledger - Google News Archive

Taxol Bristle Ball: New Delivery Method For Anti-Cancer Drug  -  Sep 17, 2007
ScienceDaily (Sep. 17, 2007) — Rice University chemists have discovered a way to load dozens of molecules of the anti-cancer drug paclitaxel onto tiny gold ... sciencedaily.com

Article: Taxol Doesn't Treat Common Breast Cancer - AP Online | …  -  Oct 10, 2007
Taxol Doesn't Treat Common Breast Cancer ... find AP Online articles. The widely used chemotherapy drug Taxol does not work for the most common form of ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Journal of Clinical Oncology Publishes Pivotal Phase III Study...  -  Nov 1, 2005
Median TTP was significantly longer with ABRAXANE than with Taxol for all ... In contrast, Grade 3 hypersensitivity reactions occurred in the Taxol group ... RedOrbit

Keep your millions, FSU tells professor  -  Dec 25, 2005
Meanwhile, he is testing a promising Taxol spinoff that could bring FSU more royalties ... But those traits, he says, helped him invent semisynthetic Taxol. ... sptimes.com

Image-based multivariate profiling of drug responses from single cells  -  Apr 1, 2007
Hydroxy urea, 2 clusters (a); oxamflatin, 3 clusters (b); taxol, 2 clusters (c); camptothecin, 3 clusters (d). The numbers of clusters were determined ... Nature.com

Article: Taxol Doesn't Treat Common Breast Cancer - AP Online | …  -  Oct 10, 2007
Taxol Doesn't Treat Common Breast Cancer ... find AP Online articles. The widely used chemotherapy drug Taxol does not work for the most common form of ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Article: Taxol Doesn't Treat Common Breast Cancer - AP Online | …  -  Oct 10, 2007
Taxol Doesn't Treat Common Breast Cancer ... find AP Online articles. The widely used chemotherapy drug Taxol does not work for the most common form of ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Event Brief of Abraxis BioScience San Antonio Breast Cancer Symposium...  -  Dec 18, 2006
Taxol in a number of oncology settings, but this is the first of several studies ... With respect to Taxol, CALGB trial called 9840 demonstrated that weekly ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Taxol Doesn't Treat Common Breast Cancer | Article from AP Online | …  -  Oct 10, 2007
Taxol Doesn't Treat Common Breast Cancer ... find AP Online articles. The widely used chemotherapy drug Taxol does not work for the most common form of ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Coral offers cancer hope  -  Sep 11, 2005
Tests show it acts on cells in the same way as Taxol, a chemotherapy drug used to treat breast, ovarian and lung cancer. Eleutherobin works by interfering ... The Age

Certican Better Than Taxol in Drug-Eluting Stents  -  Apr 22, 2008
...(April 22, 2008 - Insidermedicine) Stents that release everolimus, commonly known as Certican, help keep the blood vessels that feed the heart open and ... Insidermedicine

… Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva,...  -  Apr 18, 2005
Taxol, used to treat a wide spectrum of cancers, works by interrupting the reorganization of the cell that is necessary if it is to divide. ... Biology News Net - Biology News Net (press release)

Hasty decisions, broken faith over Taxol royalties  -  Nov 22, 2005
TK Wetherell may have been right to redirect the design of Florida State University's new chemistry building from a model for specialized research to one ... $2.95 - Daytona Beach News-Journal - NewsBank

Figure 7 : Disruption of the basal body compromises proteasomal...  -  Sep 30, 2007
...loss of BBS4 with respect to the cellular Wnt response and cannot be rescued by treatment with the microtubule stabilizer paclitaxel (Taxol). ... Nature.com

Advances in the Treatment of Metastatic Breast Cancer: An Update From...  -  Dec 8, 2005
An additional 3 trials compared single-agent taxanes (2 Taxol, 1 Taxotere), with a single ... More neuropathy was seen with the Taxol-containing regimen. ... Cancer Consultants

Early Study Shows Spice Stunts Deadly Spread To Lungs  -  Oct 16, 2005
Because Taxol is so toxic, it activates a protein that produces an ... In fact, researchers found that adding curcumin to Taxol actually enhances its effect ... sciencedaily.com

Taxol reduces breast cancer recurrence  -  Dec 28, 2005
New research finds that the cancer drug Taxol (paclitaxel), in conjunction with more concise chemotherapy periods, offers an increased chance of breast ... DentalPlans.com

… : Shorter Chemotherapy Regimen Plus Taxol Reduces Breast Cancer …  -  Dec 12, 2005
By Michael Smith,. SAN ANTONIO, Dec 12 - A shorter standard adjuvant chemotherapy regimen, augmented by weekly doses of Taxol (paclitaxel), ... MedPage Today

… Identified That Regulates Effectiveness Of Taxol Chemotherapy In...  -  Feb 25, 2007
The taxanes are Taxol (also known as paclitaxel) and Taxotere (docetaxel). Taxol was originally derived from the Pacific yew tree, and Taxotere is a ... Medical News Today - Medical News Today (press release)

MAN GETS SIX YEARS FOR FOR RIP-OFF OF TAXOL FUND  -  Aug 24, 2005
A Lake Worth man was sentenced to six years in prison for making $77000 in false claims to a fund intended to help patients who overpaid for the ... Pay-Per-View - Palm Beach Post - NewsBank

Herceptin With Weekly Taxol and Platinum Show Positive Results in...  -  Feb 3, 2005
By Chris Berrie. PARIS, FRANCE -- February 3, 2005 -- The combination of Herceptin (trastuzumab) with weekly Taxol (paclitaxel) and cisplatin is effective ... DG News

Mother Nature's pharmacy | Article from Jerusalem Post | HighBeam …  -  Mar 5, 2006
As a result of her work, a drug named Taxol was developed, ... "What I refer to are drugs from natural products such as Taxol from the yew tree, ... Pay-Per-View - Jerusalem Post - HighBeam Research

Article: TAXOL'S ROOTS IN SYRACUSE.(News) - The Post-Standard ( …  -  Oct 11, 2007
The Bristol-Myers Squibb plant in East Syracuse helped develop Taxol, a breast and ovarian cancer drug, in the ear... Pay-Per-View - Post-Standard - HighBeam Research

Article: Taxol Doesn't Treat Common Breast Cancer - AP Online | …  -  Oct 10, 2007
Taxol Doesn't Treat Common Breast Cancer ... find AP Online articles. The widely used chemotherapy drug Taxol does not work for the most common form of ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Taxol, Tamaxofin, Paclitaxel, OOPS!...or Chemo Brain! Ha!  -  Jan 3, 2008
Talk about confusing!! Doxorubicin/Adriamycin/Anastrozole /Arimidex/Paclitaxel/Taxol/Tamaxofin/Trastuzumab/Herceptin ... HealthCentral.com

Oncology; Taxol induces caspase-10-dependent apoptosis  -  Mar 1, 2005
According to a study from the United States, "Taxol (paclitaxel) is known to inhibit cell growth and trigger significant apoptosis in various cancer cells. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Tweaking Taxol Points Way to a Greener, More Productive Future. |...  -  Mar 24, 2006
Tweaking Taxol Points Way to a Greener, More Productive Future. ... find Ascribe Higher Education News Service articles. Byline: Michigan State University ... Pay-Per-View - Ascribe Higher Education News Service - HighBeam Research

Can Taxol cause continuing pain?  -  Sep 8, 2008
Question from Mary: Can Taxol cause continuing pain after treatment? It's been almost three years, but I had some problems before diagnosis of breast cancer ... Breastcancer.org

Oncology; Taxol induces caspase-10-dependent apoptosis  -  Mar 4, 2005
According to a study from the United States, "Taxol (paclitaxel) is known to inhibit cell growth and trigger significant apoptosis in various cancer cells. ... Pay-Per-View - Genomics & Genetics Weekly - Factiva, from Dow Jones

Oncology; Taxol induces caspase-10-dependent apoptosis  -  Mar 5, 2005
According to a study from the United States, "Taxol (paclitaxel) is known to inhibit cell growth and trigger significant apoptosis in various cancer cells. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

… : Did infiltrated injection site call for D/C of Taxol infusion?(Nur...  -  Feb 1, 2008
Freeman's cancer was treated with Taxol, which is highly toxic and, ... Further, the court noted that Dr. Sacks and MOG admitted that Taxol caused the ... Pay-Per-View - Nursing Law's Regan Report - HighBeam Research

Taxol settlement funds put books in Oregon libraries  -  Aug 16, 2008
BY CHRIS RIZO. SALEM, Ore. (Legal Newsline)-Oregon Attorney General Hardy Myers said beginning this week local libraries will be receiving books and CDs on ... Legal News Line

Ruud Events Honoring Mm .  -  Jan 11, 2006
...laboratory fund established from million in royalties the school has received from the cancer drug Holton developed, synthetic Taxol. that's university ... Gainesville Sun - Google News Archive

Taxol With Avastin Greatly Slowed Breast Cancer Progression, Study …  -  Jan 1, 2008
ScienceDaily (Jan. 1, 2008) — Highly positive results are reported from the first nationwide clinical study showing the benefits of an antiangiogenic agent ... sciencedaily.com

No Drugs, No Rally  -  Sep 25, 2007
The company makes Abraxane, an albumin-based formulation of Taxol, which has been competing exceptionally well against Bristol-Myers' Taxol and ... fool.com

Nano-shells carrying drug cocktail kills breast cancer tumours  -  Apr 11, 2006
The study, by a team of researchers led by Fariyal Ahmed, found that the carrier can be used to successfully transmit a cocktail of the drugs Taxol and ... Pay-Per-View - Hindustan Times - Factiva, from Dow Jones

Taxol vs. Abraxane in recurrent IBC?  -  Oct 13, 2008
Question from Barb: Can you comment on the use of Taxol vs. Abraxane in the treatment of recurrence in IBC, especially for the triple-negative cases? ... Breastcancer.org

Taxol Chemo Can Cause Tumor Cell Release  -  Jun 25, 2006
Using the CellSearch technique that quantifies circulating tumor cells, German investigators have shown that neoadjuvant chemotherapy with paclitaxel ... Medical News Today - Medical News Today (press release)

Apoptosis; Micromolar taxol induced cell necrosis in HeLa cells  -  Dec 13, 2005
2005 DEC 13 - (NewsRx.com) -- Micromolar taxol could be administered to induce cell necrosis in human cervical carcinoma HeLa cells. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

American Pharmaceutical Partners announces presentation of Abraxane …  -  Feb 25, 2005
In the overall patient population, median survival for those patients receiving Abraxane was 10 weeks longer than for patients receiving Taxol but this ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

Brand Names/Synonyms:
Taxol is also known by the following brand names and/or synonymsAbraxane; Lipopac; Onxol; PAXENE; Paclitaxel; Paclitaxel, From Pacific Yew Tree; Paxceed; TAXOL; Taxol; Taxol A; [Usan:Ban:Inn]

Drug Category:
Taxol is categorized under the following by the FDA: Antineoplastic Agents; ATC:L01CD01

Dosage Forms:
LIQUID, SOLUTION

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
5 beta,20-Epoxy-1,2a,4,7 beta,10 beta,13 alpha-hexahydroxytax-11-en-9-one





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