Terazol

This page contains recent news articles, when available, and an overview of Terazol but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Terazol
(when available)

Pharmacology and use:
Terconazole is a triazole antifungal agent available for intravaginal use. It is structurally related to imidazole-derivative antifungal agents, although terconazole and other triazoles have 3 nitrogens in the azole ring. Candidiasis (a yeast-like fungal infection) of the vulva and vagina

Mechanism Of Action:
Terconazole may exert its antifungal activity by disrupting normal fungal cell membrane permeability. Terconazole and other triazole antifungal agents inhibit cytochrome P450 14-alpha-demethylase in susceptible fungi, which leads to the accumulation of lanosterol and other methylated sterols and a decrease in ergosterol concentration.

News Articles on Terconazole

FDA Clears Perrigo Drug  -  Mar 22, 2006
This product, Perrigo said, is equivalent to Ortho-McNeil Pharmaceutical's Terazol 3 Vaginal Suppositories, 80 mg, an anti-fungal medication for the ... TheStreet.com - TheStreet.com (subscription)

First-Time Generic Approvals: Terazol 7, DDAVP Nasal Spray, Biaxin...  -  Feb 18, 2005
Feb. 18, 2005 — The US Food and Drug Administration (FDA) has approved a first-time generic formulation of terconazole vaginal cream 0.4% for the treatment ... Medscape

First-Time Generic Approvals: Novantrone, Terazol 3, Norco  -  Apr 14, 2006
April 14, 2006 -- The US Food and Drug Administration (FDA) has approved first-time generic formulations of mitoxantrone HCl 2-mg/mL injection for the ... Medscape

… Vaginal Cream, 0.4% ANDA; Generic Equivalent to Terazol-R- 7...  -  Jan 20, 2005
Taro's terconazole vaginal cream, 0.4% is bioequivalent to Ortho-McNeil Pharmaceutical's Terazol(R) 7 Vaginal Cream 0.4%. Terconazole vaginal cream is a ... $4.95 - Business Wire - ECNext

Taro Pharmaceutical Industries Ltd.  -  Feb 14, 2005
Terazol had U.S. sales of $42 million for the 12 months ended in September. Copyright 2005 Lebhar-Friedman Inc. $9.94 - Drug Store News - Alacra Store

Article: Terconazole vaginal cream approved.(PRODUCTS)(Brief Article)...  -  Apr 1, 2005
Terconazole vaginal cream 0.8% is the equivalent of Terazol(R) 3 (terconazole) vaginal ... The product is the generic equivalent to Terazol 3 vaginal cream ... Pay-Per-View - Internal Medicine News - HighBeam Research

Press Release: FDA Approves Low-dose Regimen of PREMARIN Vaginal …  -  Nov 13, 2008
Terconazole vaginal cream 0.8% is the equivalent of Terazol(R) 3 ... February 2004, Terazol(R) 3 vaginal cream 0.8% had sales of approximately ... ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: FDA Approves Duramed's Synthetic Conjugated …  -  Dec 1, 2008
Terconazole vaginal cream 0.8% is the equivalent of Terazol(R) 3 ... February 2004, Terazol(R) 3 vaginal cream 0.8% had sales of approximately ... ... Pay-Per-View - PR Newswire - HighBeam Research

Study eyes methods for compounding vaginal suppositories.(RX/News)( …  -  May 19, 2008
Terazol 3 vaginal suppositories, 80 mg suppositories Hydrocodone bitartrate Mikart Inc. Norco tablets, 7.5 and acetaminophen mg/325 mg ... ... Pay-Per-View - Chain Drug Review - HighBeam Research

Generic Drugs; US FDA grants approval for generic antifungal vaginal ...  -  Feb 19, 2005
Taro's terconazole vaginal cream, 0.4% is bioequivalent to Ortho-McNeil Pharmaceutical's Terazol 7 Vaginal Cream 0.4%. Terconazole vaginal cream is a ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Taro wins US FDA approval for Ortho-McNeil generic.  -  Feb 28, 2005
Terazol had sales of $42 M in the year ended Sep 2004. The stronger dose version (0.8%) was approved in Apr 2004. PharmaChem Vol. 4 No. 1-2. Pay-Per-View - PharmaChem - Factiva, from Dow Jones

Generic Drugs; US FDA grants approval for generic antifungal vaginal ...  -  Feb 15, 2005
Taro's terconazole vaginal cream, 0.4% is bioequivalent to Ortho-McNeil Pharmaceutical's Terazol 7 Vaginal Cream 0.4%. Terconazole vaginal cream is a ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

WPP, IPG Take J&J's US Creative  -  Nov 5, 2008
J&J's pain drugs include Duragesic and Ultram, its reproductive health/urology drugs, Ortho and Terazol, and its cancer drugs, Velcade and Leustatin. Adweek

Perrigoçš„terconazole栓剂获FDA批准  -  Mar 22, 2006
...该产�是Ortho-McNeil Pharmaceutical生产的剂�为80毫克的抗真��物Terazol 3阴� 栓剂的仿制�。Ortho-McNeil是一家强生(JNJ)旗下的公�。 ... 新浪网

Sun Herald : Photosensitive medicines listed  -  Aug 23, 2007
...sulfasalazine (Azulfidine); sulfisoxazole (Gantrisin); terconazole (Terazol); tetracycline (Achromycin); voriconazole (VFEND); zalcitabine (Hivid). ... $2.95 - Sun Herald - NewsBank

Avalon Pharmaceuticals Appoints David D. Muth to Executive Vice …  -  Sep 27, 2006
In this capacity, he was responsible for the successful launch of three significant pharmaceutical products, namely Terazol (anti-fungal), Ortho Cyclen, ... Free with registration - PR Newswire - AccessMyLibrary.com

FDA first-time generics approvals--2006.(Special Report)(Statistical...  -  Feb 19, 2007
Terazol 3 vaginal suppositories, 80 mg suppositories Hydrocodone bitartrateMikart Inc. Norco tablets, 7.5 and acetaminophen mg/325 mg tablets USP, ... Pay-Per-View - Chain Drug Review - HighBeam Research

St. Paul Pioneer Press : MANY MEDS DON'T MIX WITH THE SUN  -  Sep 21, 2005
...sulfasala-zine (Azulfidine), sulfisoxazole (Gantrisin), terconazole (Terazol), tetracycline (Achromycin), voriconazole (VFEND), zalcita-bine (Hivid). ... $2.95 - St. Paul Pioneer Press - NewsBank

Press of Atlantic City, The : Question & Answer from the pharmacy:...  -  Aug 27, 2007
...sulfasalazine (Azulfidine); sulfisoxazole (Gantrisin); terconazole (Terazol); tetracycline (Achromycin); voriconazole (VFEND); zalcitabine (Hivid). ... $2.95 - Press of Atlantic City, The - NewsBank

ALSO NOTED: Developer plans Chicago cluster; genetic tests deliver …  -  Mar 21, 2006
Perrigo has received FDA approval to sell a generic version of Ortho-McNeil Pharmaceutical's Terazol 3 Vaginal Suppositories. Report ... FierceBiotech

Yeast Infection Medication Can WORSEN Your Medical Condition  -  Jun 27, 2008
In this list are Butoconazole, Diflucan Gyne-Lotrimin, Clotrimazole (Mycelex-7), Miconazole, Vitaklenz, Nizoral, Monistat - 7, Sporanox, Terazol, ... California Chronicle

New generics.(RX)  -  May 8, 2006
AB-rated to Terazol 3 Vaginal Suppositories, 80 mg, from Ortho-McNeil Pharmaceutical, terconazole is an antifungal medication used to treat vaginal candida ... Free with registration - Drug Topics - AccessMyLibrary.com

Clotrimazole and Betamethasone (Topical).  -  Feb 1, 2006
Spectazole), ketoconazole (eg, Nizoral), miconazole (eg, Monistat, Monistat-Derm), terconazole (eg, Terazol 7), or to any of the other corticosteroids. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Par Louise Lapensée, obstétricienne-gynécologue | Propos recueillis...  -  Jul 17, 2008
...aussi tenter un traitement qui combat plusieurs souches de Candida, comme Terazol (en ovules ou en crème) ou Diflucan (médicament pris par la bouche). ... Châtelaine

Suppliers keep new products coming.  -  May 1, 2006
The product is the AB-rated equivalent to Ortho-McNeil Pharmaceutical's Terazol 3, an antifungal medication indicated for the treatment of yeast infections. ... $9.94 - Chain Drug Review - Alacra Store

Taro Reports First Quarter 2005 Results.  -  Apr 26, 2005
This prescription product is bioequivalent to Ortho-McNeil Pharmaceutical's Terazol(R) 7 Vaginal Cream 0.4%. Taro's ANDA for miconazole nitrate vaginal ... $4.95 - Business Wire - ECNext

First-time generic approvals.  -  May 1, 2006
Terconazole vaginal suppositories 80 mg (equiv to Terazol 3 vaginal suppositories) Perrigo Pravastatin tablets 10, 20, and 40 mg (equiv to Pravachol ... $9.94 - Formulary - Alacra Store

Press Release: Perrigo Company Announces Approval For Terconazole …  -  Mar 21, 2006
The product is the AB-rated equivalent to Ortho-McNeil Pharmaceutical's Terazol(R) 3 Vaginal Suppositories, 80 mg, an anti-fungal medication indicated for ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Yeast Infections; Treatment. - NWHRC Health Center - Yeast …  -  Mar 17, 2005
...terconazole (Terazol). * tioconazole (Monistat-1, Vagistat-1). Read all of this article with a FREE trial. Related newspaper, magazine, and journal articles ... Pay-Per-View - NWHRC Health Center - Yeast Infections - HighBeam Research

EBSCOhost Connection: Vaginal Yeast Infection.  -  Jan 1, 2005
Various antifungal medications are available to treat the infection, such as Monistat, Gyne-Lotrimin, Fem-stat, Terazol, and Mycelex. Subscription - Vaginal Yeast Infection - EBSCO Publishing

FDA APPROVES PERRIGO'S TERCONAZOLE  -  Mar 23, 2006
The 80-mg product is considered equivalent to Terazol 3 Vaginal Suppositories, an anti-fungal medication made by Ortho-McNeil. ... Pay-Per-View - FDAnews Drug Pipeline Alert - Factiva, from Dow Jones

Brand Names/Synonyms:
Terazol is also known by the following brand names and/or synonymsFungistat; Gyno-Terazol; Terazol; Terazol 3; Terazol 7; Terconazole; Tercospor; Triaconazole

Drug Category:
Terazol is categorized under the following by the FDA: Antifungals; Antifungals; ATC:G01AG02

Dosage Forms:
Vaginal cream and Vaginal suppositories

Absorption:
Following intravaginal administration of terconazole in humans, absorption ranged from 5-8% in three hysterectomized subjects and 12-16% in two non-hysterectomized subjects with tubal ligations

Interactions:
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Chemical IUPAC Name:
1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)piperazine





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