Tizanidine

This page contains recent news articles, when available, and an overview of Tizanidine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Tizanidine
(when available)

Pharmacology and use:
Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons. For the management of increased muscle tone associated with spasticity

Mechanism Of Action:
Tizanidine reduces spasticity by increasing presynaptic inhibition of motor neurons through agonist action at a2-adrenergic receptor sites.

News Articles on Tizanidine

Two Teens... Following Drug Bust at Rider High  -  ‎Dec 15, 2009‎
Officers identified the drug as Tizanidine. It's a muscle relaxer. Both students are... with possession of a dangerous drug. We're going to be taking a ... KAUZ

Acorda Therapeutics to Present at the 28th Annual JPMorgan Healthcare Conference  -  ‎Jan 4, 2010‎
The Company's marketed products include Zanaflex Capsules® (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Earthtimes (press release)

Multiple indictments issued for drug possession in Rochester  -  ‎Dec 26, 2009‎
...he was also found allegedly in possession of oxycodone, cocaine, Xanax, marijuana and two- and four-milligram forms of the prescription drug tizanidine, ... Foster's Daily Democrat

Can alternatives remedy nausea?  -  ‎Dec 11, 2009‎
I also take oxycodone, tizanidine, amitriptyline/perphenazine, lorazepam and sometimes lansoprazole. I was wondering if I could also take the slippery-elm ... Joliet Herald News

Cross-breeding leading to native livestock decline in Orissa  -  ‎Dec 13, 2009‎
Company Markets Citalopram, Enalapril, Famotidine, Fluoxetine, Flucanozole, Ibuprofen, Oxaprozin, Ranitidine, Tizanidine and Ciprofloxacin in the USA market ... TopNews

ЕкÑ?тракт от канабиÑ? намалÑ?ва Ñ?паÑ?тичноÑ?тта при МС 09 декември 2009  -  ‎Dec 10, 2009‎
Към наÑ?тоÑ?щиÑ? момент медикаменти на избор при Ñ?паÑ?тичноÑ?Ñ‚ Ñ?а: бензодиазепини, baclofen, dantrolene sodium и tizanidine. Тези препарати понÑ?кога Ñ?а ... DoctorBG.com

Acorda Therapeutics Reports Third Quarter 2009 Financial Results  -  ‎Nov 3, 2009‎
Financial Results and Product Update Zanaflex Capsules® (tizanidine hydrochloride) and Zanaflex® (tizanidine hydrochloride) Tablets gross sales - For the ... Reuters

Generic Name: Tizanidine, Sirdalud, pain, muscle relaxer, muscle relaxant  -  ‎Nov 11, 2009‎
Zanaflex is a short-acting drug indicated for the management of spasticity. It is used for conditions which cause the muscles to spasm such as multiple ... Pattaya Daily News

'Medical marijuana' is a Trojan horse  -  ‎Oct 22, 2009‎
In the meantime, other well tested, FDA-approved drugs are available (including baclofen and tizanidine) to reduce spasticity in MS. ... Washington Post

Acorda Therapeutics to Host Conference Call to Report Third Quarter 2009 ...  -  ‎Oct 27, 2009‎
The Company's marketed products include Zanaflex Capsules® (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Reuters

What is Lou Gehrig Disease?  -  ‎Oct 25, 2009‎
Baclofen, tizanidine, and diazepam may help to relax spastic muscles. Feeding tubes are often needed in the end stages of the disease. ... 24 Medica

A Practical Overview of Tizanidine Use for Spasticity Secondary to …  -  Apr 3, 2008
By Kamen, Leonard Henney, Herbert R III; Runyan, Jacob D. Objective: Tizanidine is an imidazoline central alpha^sub 2^- adrenoceptor agonist widely used to ... RedOrbit

Tizanidine (Systemic).(Drug overview)  -  Aug 1, 2006
Tizanidine ( tye-ZAN-i-dine) is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Oral contraceptives containing ethinyl estradiol and gestodene...  -  Apr 29, 2005
Methods: In a parallel-group study, 15 healthy women using OCs and 15 healthy women without OCs (control subjects) ingested a single dose of 4 mg tizanidine ... Nature.com

… from Pilot Pharmacokinetic Study Comparing Tizanidine Oral Spray...  -  Apr 7, 2008
Tizanidine is a leading drug indicated for the management of spasticity. Spasticity is a condition manifested in various neurological disorders, ... Genetic Engineering News - Genetic Engineering News (press release)

Dip in DRL net profit  -  May 7, 2005
Citing VAT as the reason behind the fall in domestic markets, CEO GV Prasad said: ''Fluoxetine, Tizanidine in the US and Ramipril in Europe witnessed ... Indian Express

Prescribers Warned of Tizanidine Drug Interactions  -  Apr 13, 2007
April 13, 2007 — Concomitant use of fluvoxamine or ciprofloxacin with tizanidine HCl (Zanaflex capsules and tablets, Accorda Therapeutics) is ... Medscape

Learn about Tizanidine from Consumer Reports Health.  -  Jan 1, 2008
Tizanidine is used to relieve the spasms and increased muscle tone caused by multiple sclerosis (MS, a disease in which the nerves do not function properly ... consumerreports.org

Tizanidine contraindicated for use with Luvox, Cipro.(Neurology)  -  Aug 1, 2007
The antispasticity drug tizanidine should not be used with fluvoxamine, ciprofloxacin, or other CYP1A2 inhibitors because of potentially dangerous ... $4.95 - Internal Medicine News - ECNext

How to take Tizanidine from Consumer Reports Health.  -  Jan 1, 2008
...tell your doctor and pharmacist if you are allergic to tizanidine or any other medications. tell your doctor if you are taking ciprofloxacin (Cipro) or ... consumerreports.org

For cerebral spasticity, botulinum toxin better than oral tizanidine.(...  -  Jul 1, 2007
..."Tizanidine dosage and effect were limited by the adverse events that many of the ... Tizanidine was titrated according to the label indications: 4 mg/day; ... $4.95 - Skin & Allergy News - ECNext

NovaDel Pharma (NVD) Adds Oral Spray Drug Development Candidates …  -  Sep 13, 2006
..."For instance, we expect that the ease of administering Tizanidine Oral Spray will be well suited to patients suffering from spasticity, ... StreetInsider.com - StreetInsider.com (subscription)

Acorda's Second Attempt At IPO Successful: $33M  -  Feb 13, 2006
...its marketed product, Zanaflex (tizanidine), and studies related to its preclinical programs on chondroitinase, neuregulin and remyelinating antibodies. ... BioWorld Online - BioWorld Online

Article: Tizanidine contraindicated for use with Luvox, Cipro.(Neurolo...  -  Aug 1, 2007
Tizanidine contraindicated for use with Luvox, Cipro.(Neurology) ... find Internal Medicine News articles. The antispasticity drug tizanidine should not be ... Pay-Per-View - Internal Medicine News - HighBeam Research

University of Helsinki; Researchers report dangerous interaction...  -  Jan 5, 2005
Concomitant use of ciprofloxacin and tizanidine results in severe and prolonged decrease in blood pressure and greatly enhances central nervous system ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

Adverse Drug Events; Researchers report dangerous interaction between...  -  Jan 3, 2005
Concomitant use of ciprofloxacin and tizanidine results in severe and prolonged decrease in blood pressure and greatly enhances central nervous system ... Pay-Per-View - Pain & Central Nervous System Week - Factiva, from Dow Jones

Acorda Therapeutics Elects Barry Greene, COO of Alnylam, to its Board...  -  Jan 8, 2007
The Company's marketed products include Zanaflex Capsules(TM) (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Genetic Engineering News - Genetic Engineering News (press release)

Prevent Tension Headaches With Combination Therapy  -  May 26, 2006
Tizanidine, an alpha-2 agonist, acts as a central muscle relaxant. ... The investigators concluded that the addition of tizanidine to amitriptyline during ... Medscape

Migraineurs Taking Zanaflex - MedWatch Alert  -  Apr 11, 2007
In pharmacokinetic studies where tizanidine was coadministered with either ... If you're taking Zanaflex (tizanidine) with any of the medications listed in ... HealthCentral.com

FDA Safety Labeling Changes: Fluvoxamine Maleate, Norvir, Tev-Tropin  -  May 25, 2005
The FDA notes that fluvoxamine is a potent inhibitor of several cytochrome P (CYP) isoenzymes, including CYP 1A2, whereas tizanidine is a CYP 1A2 substrate. ... Medscape

Buy On-line - zanaflex  -  Mar 2, 2007
The effect of tizanidine compared to placebo. Check out to provide data ... To minimize side effects of tizanidine with other drugs may increase the ... NETCOMPOSITES

Acorda Therapeutics Launches ZANAFLEX CAPSULES for the …  -  Apr 4, 2005
Acorda acquired ZANAFLEX(R) CAPSULES and ZANAFLEX(R) (tizanidine ... Because of the short duration of effect, treatment with tizanidine should be reserved ... $4.95 - Business Wire - ECNext

Article: Valdecoxib banned, to hit 40 drug makers. - Economic Times (...  -  May 3, 2005
Article: HPTLC method for the simultaneous estimation of Tizanidine and ... ... In this method ... and sample solutions of tizanidine and rofecoxib were ... Pay-Per-View - Economic Times - HighBeam Research

Stock Market Update, IPO profiles, Earnings Call Transcripts,...  -  Oct 5, 2005
These products contain tizanidine, one of the two leading treatments for ... There are currently 11 generic versions of tizanidine tablets on the market. ... 123Jump.com

Tension Headache Medications - Tension Headache Health Information - ...  -  Jun 19, 2008
Tizanidine. Tizanidine (Zanaflex) is a muscle relaxant that is being studied as a possible preventive drug for chronic tension-type headaches. ... New York Times

Acorda Therapeutics Announces Expansion of Zanaflex Capsules(TM) …  -  Oct 17, 2006
The Acorda sales team promotes Zanaflex Capsules(TM) (tizanidine hydrochloride). "This second expansion will allow us to reach a much greater number of ... Genetic Engineering News - Genetic Engineering News (press release)

… notified healthcare professionals of changes to the labeling for...  -  Jun 1, 2007
The product labeling has been updated to state that coadministration of tizanidine with other ciprofloxacin (CYPIA2) inhibitors, including zileuton, ... $9.94 - Formulary - Alacra Store

Acorda Therapeutics Reports Second Quarter 2006 Financial Results.  -  Aug 3, 2006
For the quarter ended June 30, 2006, gross sales were $3.9 million for Zanaflex Capsules(TM) (tizanidine hydrochloride) and $4.0 million for Zanaflex(R) ... Free with registration - Business Wire - AccessMyLibrary.com

Acorda Therapeutics Reports Third Quarter 2008 Financial Results  -  Nov 4, 2008
Zanaflex Capsules ® (tizanidine hydrochloride) and Zanaflex ® (tizanidine ... The Company's marketed products include Zanaflex Capsules ® (tizanidine hydro. International Business Times

… notified healthcare professionals of changes to the labeling for...  -  Jun 1, 2007
The product labeling has been updated to state that coadministration of tizanidine with other ciprofloxacin (CYPIA2) inhibitors, including zileuton, ... $9.94 - Formulary - Alacra Store

Paul Royalty Fund Purchases Revenue Interest in Acorda's Zanaflex …  -  Jan 19, 2006
Both products contain tizanidine hydrochloride, or tizanidine, one of the two leading treatments currently used for the management of spasticity. ... Free with registration - PR Newswire - AccessMyLibrary.com

Awful leg spasms and stiffness upon standing and at bed time if I...  -  Oct 5, 2008
Doctor has prescribed Tizanidine for spasms. The spasms are worse in my left leg. ... The drug Tizanidine is certainly one of the drugs used to address ... HealthCentral.com

Press Release: Paul Royalty Fund Purchases Revenue Interest in …  -  Jan 19, 2006
Both products contain tizanidine hydrochloride, or tizanidine, one of the two leading treatments currently used for the management of spasticity. ... Pay-Per-View - PR Newswire - HighBeam Research

Acorda Therapeutics Files Lawsuit Against Apotex Corp. and Apotex...  -  Oct 11, 2007
6455557 relating to multiparticulate tizanidine compositions, such as those sold by the Company as Zanaflex Capsules(TM). The patent expires in 2021. ... Genetic Engineering News - Genetic Engineering News (press release)

Dr. Reddy's Records Q1 FY06 Revenue Growth of 9% to Rs. 5,587 Million...  -  Jul 26, 2005
...--Decline in revenues from fluoxetine and tizanidine due to intense ... This decline is on account of lower sales from fluoxetine and tizanidine. ... $4.95 - Business Wire - ECNext

Acorda Therapeutics Files Lawsuit Against Apotex Corp. And Apotex...  -  Oct 15, 2007
6455557 relating to multiparticulate tizanidine compositions, such as those sold ... The Company's marketed products include Zanaflex Capsulesâ„¢ (tizanidine ... Medical News Today - Medical News Today (press release)

Dr. Reddy's FY05 Revenue at Rs. 19,472 Million; Net Income at Rs.211 ...  -  May 6, 2005
Our key products of fluoxetine and tizanidine in the US as well as ramipril in Europe witnessed significant competition resulting in a steep decline in the ... $4.95 - Business Wire - ECNext

My story: the baclofen pump.(a closer LOOK) | Article from Paraplegia...  -  May 1, 2008
...(tizanidine) Paraplegia News; September 1, 1995 ; 700+ words ... Tizanidine has ... used successfully for the treatment of spasticity in more than 40 ... Pay-Per-View - Paraplegia News - HighBeam Research

Article: Pfizer steps up launches from global portfolio. - Economic...  -  Mar 3, 2006
Tizanidine tablets 2 & 4 mg contributed Rs ... Tizanidine tablets 2 & 4 mg contributed Rs 212 million to the revenues in North America as ... ... Pay-Per-View - Economic Times - HighBeam Research

City man gets prison time in assault case -  -  Mar 18, 2008
Police later recovered a loaded .45-caliber handgun, ammunition, cocaine residue and a prescription drug called tizanidine from the Neon. ... $1.95 - Worcester Telegram Gazette - NewsBank

Press Release: Acorda Therapeutics to Receive Up to $10 Million from ...  -  Nov 28, 2006
The Company's marketed products include Zanaflex Capsulesâ„¢ (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... FierceBiotech

Acorda Therapeutics Reports Fourth Quarter and Full Year 2007 …  -  Feb 11, 2008
For the fourth quarter ended December 31, 2007, the Company reported gross sales of Zanaflex Capsules (tizanidine hydrochloride) of $11.8 million and gross ... Lifescience-online

Acorda Therapeutics Reports Third Quarter 2006 Financial Results.  -  Nov 2, 2006
For the quarter ended September 30, 2006, gross sales of Zanaflex Capsules[TM] (tizanidine hydrochloride) were $5.0 million and gross sales of Zanaflex([R]) ... Free with registration - Business Wire - AccessMyLibrary.com

TM for over 9 months, no relief?  -  Jul 7, 2008
Tizanidine is often a good medication for people with sleep issues. You might want to discuss your dosage and the time you take it with your doctor. ... HealthCentral.com

Actavis Totowa Finally Does The Right Thing  -  Aug 5, 2008
Tizanidine is an addictive muscle relaxer associated with hypotension (low blood pressure) and liver toxicity. Digoxin is the subject of current wrongful ... US Recall News - US Recall News (press release)

FLUOROQUINOLONE (Oral route, Injection route, Intravenous route).( …  -  May 1, 2007
Tizanidine * Trifluoperazine * Triflupromazine * Trimeprazine * Trimipramine ... Tizanidine * Tocainide * Tolazamide * Tolbutamide * Trifluoperazine ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Consensus panel guidelines for the use of intrathecal baclofen...  -  Sep 22, 2006
Oral baclofen and dantrolene are commonly used, and recently tizanidine was ... In one study on the use of tizanidine for poststroke spastic hypertonia, ... Free with registration - Topics in Stroke Rehabilitation - AccessMyLibrary.com

Dr Reddy's Labs sees FY2005 profits slump.(Pharmaceutical industry)( …  -  May 16, 2005
Our key products of fluoxetine and tizanidine in the USA, as well as ramipril in Europe, witnessed significant competition resulting in a steep decline in ... $4.95 - Pharma Marketletter - ECNext

Treating the Complications  -  Jun 10, 2006
Tizanidine (Zanaflex) is an oral drug that works after one week. In one study, 75% of patients taking tizanidine reported improvement without the leg-muscle ... HealthCentral.com

Use of Muscle Relaxants for Musculoskeletal Conditions Reviewed  -  Aug 5, 2008
Tizanidine, which also causes marked sedation, or cyclobenzaprine may be ... Although methocarbamol and metaxalone are less sedating than tizanidine and ... Medscape

Acorda Therapeutics Names John Librie Senior Vice President, Sales …  -  Apr 3, 2008
The Company's marketed products include Zanaflex Capsules(R) (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Genetic Engineering News - Genetic Engineering News (press release)

Generics makers keep new products coming.(RX/GENERICS)(Statistical …  -  Sep 17, 2007
Famotidine $40585155.29 Teva USA Acyclovir $40456581.05 Stada Pharm. naproxen $40276162.84 Caraco Tizanidine HCl $39949278.21 Ranbaxy Clarithromycin ... Free with registration - Chain Drug Review - AccessMyLibrary.com

NovaDel Reports Positive News for Neurological Drug  -  Apr 7, 2008
Tizanidine tablets, sold as Zanaflex to treat spasticity, is made by Acorda ... Tizanidine is a leading drug indicated for the management of spasticity, ... NJBIZ

Acorda Therapeutics Reports First Quarter 2008 Financial Results  -  May 5, 2008
Zanaflex(R) (tizanidine hydrochloride) Gross Sales - For the quarter ended March 31, 2008, the Company reported gross sales of Zanaflex Capsules(R) ... Genetic Engineering News - Genetic Engineering News (press release)

Rodman & Renshaw Healthcare Conference 2006 Presenter Profiles.  -  Nov 3, 2006
Acorda's marketed products include Zanaflex CapsulesTM (tizanidine hydrochloride) and Zanaflex[R] (tizanidine hydrochloride) tablets. ... $4.95 - Business Wire - ECNext

Acorda Therapeutics.(Update) | Article from Medical Marketing & Media...  -  Feb 1, 2007
The sales team promotes Zanaflex Capsules (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Paul Royalty Fund acquires a minority stake in Acorda Therapeutics- …  -  Jan 19, 2006
Acorda Therapeutics' marketed products include Zanaflex Capsules (tizanidine hydr ochloride) and…agreement with an affiliate of Paul Capita l Healthcare ... Pay-Per-View - deals - Alacra Store

Merger and Acquisition Scenario  -  Dec 27, 2008
Zanaflex Capsule (Tizanidine HCl). Neuromuscular Disorders. Multiple Sclerosis (MS). Selective Potassium Channel Blocking Agents ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Jul 26, 2008
Zanaflex Capsule (Tizanidine HCl). Neuromuscular Disorders. Multiple Sclerosis (MS). Selective Potassium Channel Blocking Agents ... $250.00 - Revere Reports - Revere

Independent Nurse: Using botox in clinical practice  -  Jun 23, 2006
Tizanidine and dantrolene require regular blood monitoring. However, they may be helpful if many muscle groups are affected by spasticity. ... Pay-Per-View - GP - Factiva, from Dow Jones

Merger and Acquisition Scenario  -  Jul 12, 2008
Zanaflex Capsule (Tizanidine HCl). Neuromuscular Disorders. Multiple Sclerosis (MS). Selective Potassium Channel Blocking Agents. Therapeutic. $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Jul 26, 2008
Zanaflex Capsule (Tizanidine HCl). Neuromuscular Disorders. Multiple Sclerosis (MS). Selective Potassium Channel Blocking Agents ... $250.00 - Revere Reports - Revere

Loislaw Federal District Court Opinions - ACORDA THERAPEUTICS, INC. …  -  Dec 29, 2008
02-1447 for tizanidine hydrochloride capsules, which the FDA approved on August 29, 2002. (Id., ¶ 10.) Apotex Inc. filed an Abbreviated New Drug Application ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Merger and Acquisition Scenario  -  Dec 27, 2008
Zanaflex Capsule (Tizanidine HCl). Neuromuscular Disorders. Multiple Sclerosis (MS). Selective Potassium Channel Blocking Agents ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Jul 26, 2008
Zanaflex Capsule (Tizanidine HCl). Neuromuscular Disorders. Multiple Sclerosis (MS). Selective Potassium Channel Blocking Agents ... $250.00 - Revere Reports - Revere

Pharmacologic agents associated with QT interval prolongation.  -  Jun 1, 2005
Tizanidine (antispastic) TABLE 3 Clinical Trials Evaluating QT Interval Prolongation With Fluoroquinolones QT Interval Prolongation in Critically III ... Pay-Per-View - Journal of Family Practice - Factiva, from Dow Jones

Pharmacologic agents associated with QT interval prolongation.  -  Jun 1, 2005
...ketoconazole, moexipril, octreotide, pentamidine, tacrolimus, and tizanidine, have been implicated in reports of QT interval prolongation (TABLE 2). ... $4.95 - Journal of Family Practice - ECNext

Spasticity - Symptoms, Causes, Tests - NY Times Health Information  -  Mar 5, 2007
Medicines for spasticity include baclofen, tizanidine, cyclobenzaprine, and benzodiazepines. In rare cases, a pump may be inserted into the spinal fluid to ... New York Times

What Are Muscle Relaxants And When Are They Used To Treat Pain?  -  Jan 2, 2008
Tizanidine or Zanaflex reduces spasticity at the level of the spinal cord and is indicated for the treatment of spasticity associated with spinal cord ... ABC News

DRL sees a tough year ahead.  -  Jun 29, 2005
...markets for two of the company's key products --fluoxetine and tizanidine --and in Europe for an active pharmaceutical ingredient (API) called ramipril. ... Free with registration - Times of India - AccessMyLibrary.com

Adjuvant analgesics for the treatment of neuropathic pain: evaluating...  -  Feb 1, 2007
The skeletal muscle relaxant tizanidine reduced pain intensity and interference with ... (78) A separate systematic review found tizanidine effective for ... Free with registration - Journal of Family Practice - AccessMyLibrary.com

Dr Reddy`s loss at Rs 51.9 cr  -  May 7, 2005
Our key products of fluoxetine and tizanidine in the US as well as ramipril in Europe witnessed significant competition, resulting in a steep decline in ... Business Standard

Central directive to withdraw licences of 1,105 drug brands  -  Jul 2, 2007
The pharma companies will add another molecule - like tizanidine or aceclofenac in combination with paracetamol and introduce it as a new drug in the market ... Hindu

Acorda Therapeutics to Host Conference Call to Report Second  -  Aug 5, 2008
The Company's marketed products include Zanaflex Capsules(R) (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Bloomberg

Acorda Therapeutics to Present at the Piper Jaffray 20th Annual  -  Nov 25, 2008
The Company's marketed products include Zanaflex Capsules^® (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Bloomberg

Acorda Therapeutics Presents Positive Data from Preclinical  -  Jul 30, 2008
The Company's marketed products include Zanaflex Capsules(R) (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Bloomberg

Acorda Therapeutics to Present at RBC Capital Markets  -  Dec 4, 2008
The Company's marketed products include Zanaflex Capsules^® (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Bloomberg

Ethypharm's Indian arm to support parent in Columbian supplies  -  Feb 11, 2006
The deal covers three products: Tizanidine Sustained Release - a skeletal muscle relaxant, Metaclopramide Sustained Release - an antiemetic and ... Hindu Business Line

Multiple Sclerosis (MS) - Medications  -  Feb 28, 2008
Medications that may reduce muscles spasms or stiffness include baclofen (Lioresal), tizanidine (Zanaflex), dantrolene (Dantrium), gabapentin (Neurontin), ... WebMD

DLR`s downhill road  -  May 14, 2005
According to the CEO, “Our key products of fluoxetine and tizanidine in the US as well as ramipril in Europe witnessed significant competition, resulting in ... Business Standard

Amyotrophic Lateral Sclerosis (ALS) - Treatment Overview  -  Aug 14, 2008
Baclofen (Lioresal), tizanidine (Zanaflex), dantrolene (Dantrium), or benzodiazepines such as diazepam (Valium), to relieve muscle stiffness, spasms, ... WebMD

Headaches? Keep that frown at bay  -  Jan 29, 2007
Only a few such agents have been studied for their efficacy to date and these were discussed at the conference, including Gabapentin, Tizanidine, Fluoxetine ... Hindu

Medicines and alcohol  -  Sep 28, 2005
Muscle relaxants – Alcohol increases the sedative effect when taken with baclofen, methocarbamol or tizanidine. Retinoids – Alcohol causes the formation of ... Malaysia Star

Elective bilateral above the knee amputation in T4-complete spinal...  -  Jun 3, 2008
The initial treatment plan was to change the patient's oral Baclofen to Tizanidine at 12–24 mg nightly. The patient was given reading material and a video ... Nature.com

Keep that frown at bay  -  Jan 27, 2007
Only a few such agents have been studied for their efficacy to date and these were discussed at the conference, including Gabapentin, Tizanidine, Fluoxetine ... Hindu

Anti-Ma2-associated encephalitis with normal FDG-PET: a case of …  -  Nov 28, 2005
His spasticity worsened—particularly in the upper body—despite therapy with intrathecal and oral baclofen at doses as high as 20 mg every 6 h, tizanidine 8 ... Nature.com

Price pressure in US cause for concern for drug cos  -  Jan 21, 2005
Dr Reddy's witnessed a 30-per cent decline in prices on its anti-depressant, fluoxetine, and its multiple sclerosis drug, tizanidine. ... Hindu Business Line

Adjuvant analgesics for the treatment of neuropathic pain: evaluating...  -  Feb 1, 2007
The skeletal muscle relaxant tizanidine reduced pain intensity and interference with ... (78) A separate systematic review found tizanidine effective for ... $4.95 - Journal of Family Practice - ECNext

Steelman v. Baker, No. 9:05cv244 (EDTex. 02/28/2006)  -  Feb 28, 2006
...fluoxetine, amoxicillin, allegra, lactulose, chlorex, metoprolol, tramadol, neurontin, spironolactone, carisoprodol, valsartan, and tizanidine. ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

St. Paul Pioneer Press : LIVER TESTS MANDATED TO AVOID SUDDEN …  -  Apr 13, 2005
...testosterone (AndroGel, Testim), tizanidine (Zanaflex), tolcapone (Tasmar), valproic acid (Depakote), Voriconazole (Vfend), zileuton (Zyflo). ... $2.95 - St. Paul Pioneer Press - NewsBank

The reason for those liver tests.  -  Mar 25, 2005
...testosterone (AndroGel, Testim), tizanidine (Zanaflex), tolcapone (Tasmar), valproic acid (Depakote), Voriconazole (Vfend), zileuton (Zyflo). ... Free with registration - Sun Herald - AccessMyLibrary.com

Author: TODD RUGER todd.ruger@heraldtribune.com  -  Jan 24, 2007
Kinnard said he can turn muscle relaxant Tizanidine into a topical cream that takes about 10 minutes to end tension headaches when applied to the back of ... $2.95 - Sarasota Herald-Tribune - NewsBank

Police warned of vendetta  -  Apr 11, 2008
...possession of the prescription drug tizanidine without a prescription, reckless operation of a motor vehicle, unlawful possession of ammunition, ... $1.95 - Worcester Telegram Gazette - NewsBank

مرض التصلب اللويحي المتعدد (Multiple Sclerosis MS)  -  Oct 12, 2007
التي تعمل على إرخاء العضلات Muscle relaxant مثل الباكلوÙ?ين Baclofen والتيزانيديدن Tizanidine. ... الغد الأردني

Euroetika, Distribuidor Ethypharma  -  Mar 15, 2006
El acuerdo rige para los productos Tizanidine, un relajante muscular; Metaclopramide, droga para las naúseas y para control postquimioterapeutico; ... El Tiempo - El Tiempo (Colombia)

Acorda Therapeutics' President and CEO Ron Cohen, MD Named Ernst …  -  Jun 29, 2007
The Company's marketed products include Zanaflex Capsules(TM) (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Free with registration - Business Wire - AccessMyLibrary.com

Acorda Therapeutics to Present at the Acumen BioFin Rodman & …  -  Oct 31, 2007
The Company's marketed products include Zanaflex Capsules[TM] (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Free with registration - Business Wire - AccessMyLibrary.com

Acorda Therapeutics to Present at the 2007 UBS Global Life Sciences …  -  Sep 19, 2007
The Company's marketed products include Zanaflex Capsules(TM) (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Free with registration - Business Wire - AccessMyLibrary.com

Fampridine-SR Data Sends Acorda Stock Through Roof  -  Sep 26, 2006
...team already reaches with the spasticity drug Zanaflex (tizanidine), and find a European partner for regulatory and commercialization efforts there. ... BioWorld Online - BioWorld Online

Acorda Therapeutics to Present at Bank of America Health Care …  -  May 23, 2007
The Company's marketed products include Zanaflex Capsules(TM) (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Free with registration - Business Wire - AccessMyLibrary.com

Acorda Therapeutics Responds to Third Point Letter  -  Feb 23, 2007
The Company's marketed products include Zanaflex Capsules(TM) (tizanidine hydrochloride), a short-acting drug for the management of spasticity. ... Genetic Engineering News - Genetic Engineering News (press release)

Brand Names/Synonyms:
Tizanidine is also known by the following brand names and/or synonymsCHEMBANK1846; Pramiracetam; Sirdalud; Ternelin; Tizanidina [Inn-Spanish]; Tizanidine; Tizanidine Hcl; Tizanidinum [Inn-Latin]; Zanaflex

Drug Category:
Tizanidine is categorized under the following by the FDA: Muscle Relaxants; Anticonvulsants; Analgesics; Skeletal Muscle Relaxants; ATC:M03BX02

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-8-thia-7,9-diazabicyclo[4.3.0]nona-2,4,6,9-tetraen-5-amine





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