Tobradex

This page contains recent news articles, when available, and an overview of Tobradex but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Tobradex
(when available)

Pharmacology and use:
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections. For the treatment of pseudomonas aeruginosa lung infections

Mechanism Of Action:
Tobramycin binds irreversibly to one of two aminoglycoside binding sites on the 30 S ribosomal subunit, inhibiting bacterial protein synthesis. Tobramycin may also destabilize bacterial memebrane by binding to 16 S 16 S r-RNA. An active transport mechanism for aminoglycoside uptake is necessary in the bacteria in order to attain a significant intracellular concentration of tobramycin.

News Articles on Tobramycin

TobraDex in My Practice  -  Jun 24, 2005
Often we encounter inflammatory disease with a confirmed or questionable underlying infective component. It may be that we are simply concerned about ... RedOrbit

Having trouble stopping tobradex or fluorometholone. Can someone help.  -  Jun 11, 2007
...> am down to 1 drop every two days but I can't seem to go much longer. > feel like it can cause another erosion. Can someone help me understand ... earthvision.net

Alcon shrs drop 35 pct on dismal earnings, outlook  -  Oct 23, 2008
TobraDex is used to treat eye inflammation. Weinstein anticipates 'a challenging environment for the next several quarters' for US pharmaceutical sales. ... Forbes

2. Good correction in both eyes but one eye better than the other...  -  Jul 25, 2006
Prescribed TOBRADEX 2x daily & told my wife to "come back if needed" (as ... Does this sound like the correct course of treatment (ie TOBRADEX and lots of ... USAEyes

Event Brief of Q2 2007 Alcon Inc. Earnings Conference Call - Final.  -  Jul 26, 2007
Filing US NDA TobraDex ST. 4. Presentation of initial three-month interim ... TobraDex has experienced a 0.8% share decline YTD as a result of a new entry ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Alcon's Second Quarter Sales Rise 17.9 Percent; Net Earnings Increase...  -  Jul 23, 2008
...by Vigamox(R) ophthalmic solution in the United States and sales growth for TobraDex(R) ophthalmic suspension and ointment outside the United States. ... Genetic Engineering News - Genetic Engineering News (press release)

ISTA Provides Regulatory Update on T-Pred NDA Filing.  -  May 4, 2007
Tobrex and Tobradex are registered trademarks of Alcon Laboratories. Zylet is a registered trademark of Bausch & Lomb. Free with registration - PR Newswire - AccessMyLibrary.com

EDITED BRIEF  -  Apr 24, 2008
Disappointed not to have received approval of TobraDex ST yet, moving forward with next steps Co. needs. to follow to gain approval. ... $54.00 - Thomson StreetEvents - Alacra Store

FINAL TRANSCRIPT  -  Apr 24, 2008
Although we are disappointed not to have received approval of TobraDex ST yet, we are moving forward. with the next steps we need to follow to gain. $54.00 - Thomson StreetEvents - Alacra Store

Corneal endothelial function after phacoemulsification using the...  -  Mar 3, 2006
Postoperatively patients received tobramycine+dexamethasone eyedrops (TobraDexâ„¢, Alcon Laboratories) five times for 4 weeks. The patients were examined on ... Nature.com

Pink Eye| Eye Infection| Children Eye| Eye Care| Conjunctivitis  -  Jul 31, 2007
The topical antibiotic eye drops, which might include Polytrim, Tobramycin (Tobrex, TobraDex), Gentamycin (Garamycin, Gentacidin) and Sulfonamides ... Oneindia

Agustín Fonseca  -  Jan 31, 2007
Me diagnosticaron de blefaritis y queratitis derivada hace unos 3 meses, y desde entonces, llevo con 3 tipos d antibiótico (tobrex, tobradex, y otro por vía ... elmundo.es

Badminton Central Discussion Forums - View Single Post - Badminton …  -  Nov 9, 2005
...tobradex: give the pic of carola bott to your friend. he'll be drooling over it. in general, kinda true tho. most hot girl is not interested in playing ... Badminton Central

Q1 2006 Alcon Inc. Earnings Conference Call - Part 1.  -  Apr 25, 2006
...success in building our major brands, including Travatan, Vigamox and Ciprodex Otic, while maintaining our positions with Patanol and TobraDex in the US ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

Marea întăreÅŸte imunitatea copilului  -  Jul 17, 2008
...smecta, hidrasec), antibiotice (amoxicilina), picături nazale, antihistaminice (peritol, claritine); soluţie oftalmică (tobradex). ... Adevărul

Tracking Trends in Pharmacologic Therapy  -  Mar 31, 2006
Two combination agents, tobramycin 0.3%-loteprednol etabonate 0.5% suspension (Zylet) and tobramycin 0.3%-dexamethasone (TobraDex), offer similar coverage ... RedOrbit

Global top 200 brand-name drugs ranked by retail sales in dollars and...  -  Feb 21, 2005
171499 -87.3 135 Zyrtec-D $161758 22.3% 136 Differin 161587 3.9 137 Catapres-TTS 154143 7.8 138 Tobradex 153757 -4.2 139 Atacand 153224 -2.1 140 Humulin ... $20.00 - Drug Topics - Alacra Store

Contact lens acute red eye (CLARE).(Signs and Symptoms)(Disease/ …  -  Mar 15, 2006
Perhaps the most effective and easiest therapeutic regimen is to use an antibiotic-corticosteroid combination, such as TobraDex[R] or Zylet[R], ... Free with registration - Review of Optometry - AccessMyLibrary.com

Alcon Announces Leadership Change to Research and Development …  -  Mar 10, 2008
Vigamox([R]) for bacterial conjunctivitis, TobraDex([R]) for eye infections and inflammation, the AcrySof([R]) line of intraocular lenses for cataract ... Free with registration - Business Wire - AccessMyLibrary.com

Alcon's Second Quarter Sales Rise 12.3 Percent  -  Jul 25, 2007
...as global growth of Vigamox(R) ophthalmic solution, NEVANAC(R) ophthalmic suspension, and TobraDex(R) ophthalmic suspension were partially offset by ... Genetic Engineering News - Genetic Engineering News (press release)

First-half frailty: talk of an upturn in second-half ad revenues is...  -  Nov 1, 2005
...ad expenditures: Varilux and Crizal Alize Lenses, up from 463rd to 5th: and Alcon's Tobradex Ophthalmic Suspension and ointment, up from 65th to 10th. ... $9.94 - Medical Marketing & Media - Alacra Store

Top 200 brand-name drugs by units in 2005.(rankings )  -  Mar 20, 2006
Armour 2382 -4.6 131 Lidoderm 2352 33.7 132 Tobradex 2343 -5.2 133 Humulin 70/30 2338 -15.3 134 Atacand 2316 -9.3 135 Ultracet 2296 -57.0% 136 Augmentin ... Free with registration - Drug Topics - AccessMyLibrary.com

Dual Recognition for Alcon, Inc. With Frost & Sullivan's 2005 Product...  -  Nov 8, 2005
...eye allergy drops (Patanol(R) ophthalmic solution), and combination anti-infectives and anti-inflammatories (Tobradex(R) ophthalmic suspension). ... $4.95 - PR Newswire - ECNext

Alcon's First Quarter Sales Rise 14.3 Percent.(Financial report)  -  Apr 25, 2007
...market share gains by Vigamox([R]) ophthalmic solution in the United States and solid sales growth for TobraDex([R]) ophthalmic suspension and ointment. ... $4.95 - Business Wire - ECNext

Q3 2006 Alcon Inc. Earnings Conference Call - Final.  -  Oct 24, 2006
The only products where we are not growing faster than the underlying markets are Patanol and TobraDex, both of which have market shares of more than 60% in ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Alcon "neutral," target price raised  -  Feb 11, 2008
Despite already having a dominant position in the surgical market, Alcon continues to expand its share, the analysts add. The Tobradex XT is unlikely to be ... newratings.com

Patient has right-eye proptosis for 2 weeks: a 61-year-old woman has ...  -  Nov 15, 2007
The patient's symptoms had improved with tobramycin and dexamethasone ophthalmic ointment (TobraDex, Alcon). There was no associated trauma, ... Free with registration - Ophthalmology Times - AccessMyLibrary.com

Alcon reports 16.2% increase in first-quarter sales  -  Apr 24, 2008
...to market share gains by Vigamox (moxifloxacin 0.5%) in the United States and growth of TobraDex (tobramycin-dexamethasone) abroad, the release said. ... OSN SuperSite

Q2 2007 Alcon Inc. Earnings Conference Call - Final.  -  Jul 26, 2007
...the filing of our US NDA on TobraDex ST, and as you all saw in the press release last week, the presentation of initial three-month interim data from ... Free with registration - Fair Disclosure Wire - AccessMyLibrary.com

Alcon's First Quarter Sales Rise 16.2 Percent; Net Income Increases...  -  Apr 23, 2008
...by Vigamox(R) ophthalmic solution in the United States and sales growth for TobraDex(R) ophthalmic suspension and ointment outside the United States. ... Genetic Engineering News - Genetic Engineering News (press release)

Dược phẩm vẫn tiếp tục tăng giá  -  Mar 3, 2005
Thuốc nhá»? mắt V.Rohto tăng từ 29.000 đồng lên 31.0000/lá»?; Tobradex nước (nhá»? mắt), tăng từ 40.000 đồng lên 43.000 đồng/lá»?; kháng sinh răng Rodogyl Pháp từ ... Ngưá»?i Lao Ä?á»™ng

Loislaw Federal District Court Opinions - SWEARINGEN v. BEASLEY ( …  -  Jul 26, 2006
I have encouraged her to stay on the Tobradex drops QID and return to reexamination in 1 week. I feel she is over the worst of the injury. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Q4 2006 Alcon Inc. Earnings Conference Call - Part 1.  -  Feb 8, 2007
TobraDex and Patanol retained their market-leading positions with international growth more than offsetting small market share losses in the US. ... Free with registration - America's Intelligence Wire - AccessMyLibrary.com

Technology in Brief  -  Mar 24, 2008
Vigamox for bacterial conjunctivitis, TobraDex for eye infections and inflammation, the AcrySof line of intraocular lenses for cataract surgery, ... Fort Worth Business Press

Domanda di Occhio  -  Sep 23, 2005
Ho messo il collirio tobradex e la mattina seguente la macchia rossa non c'era più. Sono andato comunque da un oculista, il quale mi ha detto che ... Dica 33

The blepharitis battle.(MEDICAL MAILBOX)(Brief article)  -  Nov 1, 2006
..."Tobradex eye drops contain a steroid to decrease inflammation associated with blepharitis. The use of steroids, however, can increase the incidence of ... $4.95 - Saturday Evening Post - ECNext

Movers and Shakers  -  Apr 25, 2008
Vigamox (moxifloxacin 0.5%) for bacterial conjunctivitis, TobraDex (tobramycin-dexamethasone) for eye infections and inflammation, the AcrySof line of ... OSN SuperSite

Top 200 brand-name drugs by retail dollars in 2006.(COMMUNITY …  -  Feb 19, 2007
171873 -32.6 163 Zyrtec Syrup 171381 -8.2 164 Alphagan P 169571 -7.5 165 Differin 168884 0.0 166 Zyrtec-D 168028 2.7 167 Tobradex 166663 7.5 168 Aranesp ... Free with registration - Drug Topics - AccessMyLibrary.com

United States top 200 brand-name drugs by retail sales in dollars and...  -  Mar 6, 2006
DuoNeb 161270 19.6 172 Prozac 158240 -12.9 173 Tamiflu 157488 389.2 174 Tobradex 155102 0.9 175 NovoLog Mix 70/30 155049 84.6 176 Amnesteem 153534 -16.9 ... $20.00 - Drug Topics - Alacra Store

Marginal keratitis.(CORNEA)(Disease/Disorder overview)  -  Mar 15, 2007
Another very acceptable option in MK associated with blepharitis is an antibiotic-steroid combination, such as TobraDex (tobramycin/dexamethasone, ... Free with registration - Review of Optometry - AccessMyLibrary.com

Article: Advanced Technology Systems Gets VHA Contract - Wireless …  -  Oct 26, 2006
TobraDex ophthalmic suspension. - Advanced technology intraocular lenses rose 38.3 percent ... Wireless News. Article: WMS Opens Casino Evolved Technology ... Pay-Per-View - Wireless News - HighBeam Research

Getting started in therapeutics (C7749)  -  Oct 26, 2007
...framycetin and tobramycin, are not used alone in the UK but are available in the antibiotic-steroid combinations Sofradex and Tobradex respectively. ... Optician Online

Global top 300 brand-name pharmaceuticals by sales, manufacturer, and...  -  Apr 28, 2008
GlaxoSmithKline Imitrex 00173047800 268 Galderma Differin 00299591045 269 Alcon Tobradex 00065064705 270 Amgen Sensipar 55513007330 271 GlaxoSmithKline ... $20.00 - Chain Drug Review - Alacra Store

Merger and Acquisition Scenario  -  May 20, 2006
...synthesis and supressing the full immune response. Buyer Products:. CiproDex Ocular (Ciprofloxacin/Dexamethasone); Tobradex (Tobramycin/Dexamethasone) $250.00 - Revere Reports - Revere

Antibiotics: rather than prescribing an antiobiotic that will "do no...  -  Jun 15, 2007
...more than sterile leukocytic infiltrates that usually merit a combination product such as Zylet or TobraDex--or generic Maxitrol, if cost is an issue. ... Free with registration - Review of Optometry - AccessMyLibrary.com

Security With Advanced Technology and PepperBall Technologies Merge …  -  Sep 29, 2008
TobraDex ophthalmic suspension. - Advanced technology intraocular lenses rose 38.3 percent ... Wireless News. Article: WMS Opens Casino Evolved Technology ... Pay-Per-View - Wireless News - HighBeam Research

Article: QLP Gets 'Best Paper' of Session at IMAPS Advanced Technology...  -  Sep 27, 2008
TobraDex ophthalmic suspension. - Advanced technology intraocular lenses rose 38.3 percent ... Wireless News. Article: WMS Opens Casino Evolved Technology ... Pay-Per-View - Wireless News - HighBeam Research

Otite catarrale persistente - Infezioni  -  Oct 18, 2006
...esterna in fase di guarigione" e visto che dovevo recarmi al mare mi ha prescritto una cura antibiotica con Agumentin per 8gg + tobradex per 7 gg. ... Dica 33

Alcon's Third Quarter Sales Rise 11.0 Percent.  -  Oct 24, 2007
...solution and NEVANAC([R]) ophthalmic suspension, as well as international growth of TobraDex([R]) ophthalmic suspension contributed to the increase. ... $4.95 - Business Wire - ECNext

Loislaw Federal District Court Opinions - WOJAN v. ALCON …  -  Sep 15, 2008
During the relevant time period, Plaintiff was responsible for Vigamox, Travatan, Patanol, TobraDex and for part of 2005, a newly launched product, Nevanac. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Domanda di Infezioni  -  Nov 2, 2006
...premetto che frequento la piscina regolarmente 2 volte la settimana oramai da 3 anni, l'ho curata con gocce Tobradex e antibiotico Cedax per 5 gg. ... Dica 33

Gakujo Co Ltd intends a stock buyback - Deal Snapshot - AlacraStore. …  -  Sep 15, 2008
Ice, Software cream, Calais, Potage & soup, Whip…therapeutic drugs, contact lens care solutions and surgical instruments and equipment…and Tobradex. ... Pay-Per-View - deals - Alacra Store

Feeling the pinch: slight gains in ad spending were reported among...  -  May 1, 2008
They are Opti-Free Replenish Multi-Purpose Solution, which retained the top spot, Travatan Z, up from 68th to 2nd on a 238% boost in spend and the Tobradex ... $20.00 - Medical Marketing & Media - Alacra Store

Advanced Technology Systems Secures $4.4 Million Pact with Nashville ...  -  Jan 10, 2007
TobraDex ophthalmic suspension. - Advanced technology intraocular lenses rose 38.3 percent ... Wireless News. Article: OSI Systems Secures Follow on Order ... Pay-Per-View - Wireless News - HighBeam Research

Alcon's profits soar 79% in 3rd quarter.  -  Nov 19, 2007
In addition, sales of anti-infective and anti-inflammatory agents, such as Vigamox, Nevanac and TobraDex, grew 9.2% to $191.1 million, while Alcon's allergy ... $9.94 - Pharma Marketletter - Alacra Store

Security With Advanced Technology Reports Developments With Its Less-...  -  May 11, 2008
TobraDex ophthalmic suspension. - Advanced technology intraocular lenses rose 38.3 percent ... Wireless News. Article: OSI Systems Secures Follow on Order ... Pay-Per-View - Wireless News - HighBeam Research

Security With Advanced Technology Demos Its AgileMesh Solutions at …  -  Aug 27, 2007
TobraDex ophthalmic suspension. - Advanced technology intraocular lenses rose 38.3 percent ... Wireless News. Article: OSI Systems Secures Follow on Order ... Pay-Per-View - Wireless News - HighBeam Research

Top 200 brand-name drugs by retail dollars in 2006.(COMMUNITY …  -  Feb 19, 2007
171873 -32.6 163 Zyrtec Syrup 171381 -8.2 164 Alphagan P 169571 -7.5 165 Differin 168884 0.0 166 Zyrtec-D 168028 2.7 167 Tobradex 166663 7.5 168 Aranesp ... $4.95 - Drug Topics - ECNext

Loislaw Federal District Court Opinions - HOELCEL v. ARKANSAS …  -  Jun 5, 2007
Corneal scarring was noted and bifocals and Tobradex were prescribed for the plaintiff. See DE #88, Ex. 1, Ex. 4 p. 1. A second visit in April, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Top 200 brand name drugs by units in 2006.(COMMUNITY PRACTICE)( …  -  Mar 5, 2007
Pulmicort Respules 2389 -0.7 125 Tobradex 2371 1.2 126 Trivora-28 2348 -10.7 127 Alphagan P 2291 -8.9 128 Dilantin Kapseals 2267 -14.0 129 Provigil 2234 ... $4.95 - Drug Topics - ECNext

Caringo Names Jan Van Riel as VP of Advanced Technology | Article …  -  Mar 21, 2008
TobraDex ophthalmic suspension. - Advanced technology intraocular lenses rose 38.3 percent ... Wireless News. Article: OSI Systems Secures Follow on Order ... Pay-Per-View - Wireless News - HighBeam Research

Security With Advanced Technology Debuts AvurtIM-5 Launcher | Article...  -  Sep 4, 2007
TobraDex ophthalmic suspension. - Advanced technology intraocular lenses rose 38.3 percent ... Wireless News. Article: OSI Systems Secures Follow on Order ... Pay-Per-View - Wireless News - HighBeam Research

United States top 200 brand-name pharmaceuticals by retail sales in …  -  Feb 19, 2007
171873 -32.6 163 Zyrtec Syrup 171381 -8.2 164 Alphagan P 169571 -7.5 165 Differin 168884 0.0 166 Zyrtec-D 168028 2.7 167 Tobradex 166663 7.5 168 Aranesp ... $20.00 - Drug Topics - Alacra Store

Episcleritis nodular - Augenarzt- Sprechstunde - Gesundheit und...  -  Sep 2, 2006
Die Behandlung war uns ist mit Augentropfen "TobraDex"(pro ml 1 mg dexametasona und 3 mg tobramicina) und abends eine Pomade "OFTALMOLOSA CUSI DE ICOL" (pro ... QualiMedic

Augenschmerzen - Augenarzt- Sprechstunde - Gesundheit und Medizin …  -  Jun 5, 2007
Ich war beim Arzt, der hat eine Bindehautentzündung "festgestellt", ich habe Tobradex-Tropfen 4Xtäglich verordnet bekommen, habe aber weiterhin Beschwerden ... QualiMedic

Ursache anderungen Scharfe nach KataraktOpera  -  May 27, 2007
Andert sich dass noch wenn Ich aufhore mit die Tropfen (Tobradex). Was ist die Ursache fur diese Anderungen? Die Linse ist aus Acryl, die andert sich ja ... Onmeda

ì?˜ë£Œê³„ ì •ë¡  메디í?¬ë‰´ìФ  -  Apr 16, 2008
...예컨대 Travatan, Patanol � Vigamox, Tobradex 안연고 � Systane �안약 등� 안약 � 성장� 주�한 것�다. 회사측� 공장� 설립하여 고� 성장하고 있는 아시아 ... 메디�뉴스

Domanda di Occhio  -  Mar 26, 2008
...anche perchè da circa due mesi soffre spesso di congiuntivite curata con il tobradex .vuole fargli fare praticamente una visita oftamologica perche ... Dica 33

Oogmedicatie onder de loep  -  Oct 30, 2008
...zijn de middelen bij een ooginfectie 300.000 keer verstrekt, waarvan de combinatie dexamethason met tobramycine (Tobradex®) met 200.000 keer het vaakst. ... gezondheid.nl

Sujet: Oeil qui pleure  -  Apr 11, 2008
...donné... quand je prend du TOBRADEX (cortizone) ça fonctionne super bien. pendant 15 jours (le temps du traitement) et ça revient de + belle... ... E-Santé.fr

Congiuntivite con annebbiamento visivo - Occhio  -  Mar 21, 2008
A quel punto il medico di base mi ha prescritto dapprima un 1° collirio TOBRADEX per l'arrossamento del occhi, poi a distanza di 1-2 settimane oltre ... Dica 33

Oogmedicatie onder de loep  -  Nov 3, 2008
...zijn de middelen bij een ooginfectie 300.000 keer verstrekt, waarvan de combinatie dexamethason met tobramycine (Tobradex®) met 200.000 keer het vaakst. ... Zorgkrant

Remedios para la conjuntivitis están escasos  -  Nov 11, 2008
...los encargados reportaron escasez de Todex, Terramicina oftálmica, Tobrex, Tobradex y otros ungüentos y fármacos para atacar el mal. ... EntornoInteligente

Brand Names/Synonyms:
Tobradex is also known by the following brand names and/or synonyms3'-Deoxykanamycin B; Aktob; CHEMBANK2411; Distobram; Gernebcin; NF 6; Nebcin; Nebramycin; Nebramycin 6; Nebramycin Factir 6; Nebramycin Factor 6; Nebramycin Vi; Obracin; Obramycin; T4014; TOBRAMYCIN; Tenebrimycin; Tenemycin; Tobi; Tobracin; Tobradex; Tobradistin; Tobramaxin; Tobramitsetin; Tobramycetin; Tobramycin 98%; Tobramycin Base; Tobramycin Sulfate; Tobrasone; Tobrex

Drug Category:
Tobradex is categorized under the following by the FDA: Anti-bacterial Agents; Aminoglycosides; ATC:J01GB01; ATC:S01AA12

Dosage Forms:
Ophthalmic Ointment; POWDER FOR SOLUTION; Solution for oral inhalation; Ophthalmic Solution; Oral Solution; IV Solution

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
4-amino-2-[4,6-diamino-3-[3-amino-6-(aminomethyl)-5-hydroxy-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-6-(hydroxymethyl)tetrahydropyran-3,5-diol





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