Topamax

This page contains recent news articles, when available, and an overview of Topamax but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Topamax
(when available)

Pharmacology and use:
Topiramate is an anticonvulsant indicated in the treatment of epilepsy and migraine. The precise mechanisms by which Topiramate exerts its anticonvulsant and migraine prophylaxis effects are unknown; however, preclinical studies have revealed four properties that may contribute to Topiramate's efficacy for epilepsy and migraine prophylaxis. Electrophysiological and biochemical evidence suggests that Topiramate, at pharmacologically relevant concentrations, blocks voltage-dependent sodium channels, augments the activity of the neurotransmitter gamma-aminobutyrate at some subtypes of the GABAA receptor, antagonizes the AMPA/kainate subtype of the glutamate receptor, and inhibits the carbonic anhydrase enzyme, particularly isozymes II and IV. Used for the treatment of partial or primary generalized tonic-clonic seizures also used as a treatment for adults with partial-onset seizures. Also indicated for prophylaxis of migraine headaches

Mechanism Of Action:
Topiramate most likely exerts its actions by four mechanisms: (1) blockage of voltage-dependent sodium channels, (2) augmentation of the activity of the neurotransmitter gamma-aminobutyrate at some subtypes of the GABAA receptor, (3) antagonism of the AMPA/kainate subtype of the glutamate receptor, (4) inhibition of the carbonic anhydrase enzyme.

News Articles on Topiramate

Doctors: Combination of Drugs Found in Brittany Murphy's Home Could Be Deadly  -  ‎Dec 23, 2009‎
..."There are two medicines here that are basically used as mood stabilizers in psychiatry — and that's the Topamax and the carbamazepine, which is also known ... FOXNews

Brittany Murphy's dad, Angelo Bertolotti, skips daughter's Christmas Eve funeral  -  ‎Dec 25, 2009‎
Brittany's father also was surprised at the multitude of drugs found at the starlet's home, including the anti-seizure medicine Topamax, anti-anxiety ... New York Daily News

Brittany Murphy Had "Large Amounts" of Prescription Meds in Bedroom  -  ‎Dec 22, 2009‎
I take topamax and propranolol for migraines. The propranolol is better at making the migraine stop in less than 30 minutes. From the med list it can pretty ... Us Magazine

Husband: Brittany Didn't "Take Anything" Dangerous Morning She Died  -  ‎Dec 23, 2009‎
According to the the coroner investigation notes (obtained by TMZ.com), medications confiscated included Topamax (anti-seizure meds also to prevent ... Us Magazine

J&J to pay $785 million for sinus-surgery company  -  ‎Dec 16, 2009‎
...to offset plunging sales of its big medicines now facing generic competition, including schizophrenia treatment Risperdal and anti-convulsant Topamax. ... Reuters

Coroner Continues Examining Brittany Murphy's Cause of Death  -  ‎Dec 23, 2009‎
Ativan is often prescribed as an anti-anxiety drug, while Topamax is an anti-seizure medication. An obviously important question to answer is if any or all ... TheWrap

Indian drug makers maintain pace of US marketing approvals  -  ‎Jan 3, 2010‎
Drugs like Merck's Fosamax, Johnson & Johnson's Topamax, GlaxoSmithKline's Advair and Lamictal, Wyeth's Effexor XR, Astella's heart disease injection, ... Business Standard

Since Doherty was in court anyway ...  -  ‎Dec 23, 2009‎
...found dead Sunday: Topamax, an anti-seizure medication; depression fighter Fluoxetine; anti-anxiety Ativan; and pain relievers Vicoprofen and Propranolol. The Gazette (Montreal)

US stars are falling victim to prescription drugs  -  ‎Dec 26, 2009‎
Other medicines on the list include treatments for epilepsy, such as Topamax, powerful pain relievers like Hydrocodone and Vicoprofen, and anti-depressants ... The Guardian

Brittany Murphy death certificate; cause of death defered  -  ‎Dec 29, 2009‎
Topamax (anti-seizure meds also to prevent migraines), Methylprednisolone (anti-inflammatory), Fluoxetine (depression med), Klonopin (anxiety med), ... San Francisco Chronicle (blog)

Hollywood Looses Another Star.  -  ‎Dec 23, 2009‎
TMZ reports that the medications included Topamax (an anti-seizure medication also used to prevent migraines), Methylprednisolone (an anti-inflammatory), ... TransWorldNews (press release)

Study Eyes Epileptics' Use of Generic Drugs  -  ‎Jan 4, 2010‎
Drugstore.com lists 60 100 mg. tablets of Topamax, an epilepsy drug, at $451.60; its generic equivalent is listed at $49.99. Kathleen Jaeger, president of ... PharmaLive.com (press release)

Experts: Brittany Murphy might have died from drug over dosage  -  ‎Dec 23, 2009‎
They included Topamax (anti-seizure meds that also prevent migraines), Methylprednisolone (anti-inflammatory), Fluoxetine (for depression), Klonopin and ... Thaindian.com

Wednesday Gossip-a-thon: The Two Weeks of Drama Edition  -  ‎Dec 30, 2009‎
TMZ reports there were many prescription drugs in the house prescribed to Murphy, her husband, her mother and other people, including Topamax (anti-seizure ... fwdailynews.com

Arena files for approval for weight loss drug  -  ‎Dec 22, 2009‎
Qnexa combines relatively low doses of the generic stimulant phentermine with the epilepsy drug topiramate, sold under the brand name Topamax. ... Reuters

Brittany Murphy was suffering from heart and menstrual problems!  -  ‎Dec 25, 2009‎
His remarks came after officials found prescription pills in her Hollywood Hills home at Los Angeles (where she died) that included 'Topamax' and ... Entertainment and Showbiz!

The Top Health Stories of 2009  -  ‎Dec 31, 2009‎
In Murphy's room, paramedics found Topamax, Methylprednisolone, Fluoxetine, Klonopin, Carbamazepine, Ativan Vicoprofen, Propranolol, Biaxin and Hydrocodone. ... eMaxHealth

Expert: Drugs likely killed Brittany Murphy  -  ‎Dec 22, 2009‎
They included Topamax (anti-seizure meds that also prevent migraines), Methylprednisolone (anti-inflammatory), Fluoxetine (for depression), Klonopin and ... MiamiHerald.com

Vigabatrin (Sabril®): A New Epilepsy Drug -- With Strings Attached  -  ‎Dec 31, 2009‎
...oxcarbazepine (Trileptal®), pregabalin (Lyrica®), rufinamide (Banzel™), tiagabine (Gabitril®), topiramate (Topamax®), and zonisamide (Zonegran®). ... Medscape

The Shadowy Science Of Sex Addiction  -  ‎Dec 22, 2009‎
There is a report of a single case in which Topamax, an epilepsy drug, reversed hypersexuality. Testosterone suppressors are reserved for criminal sexual ... Forbes

The star may have had a lethal collection of legal drugs from many sources ...  -  ‎Dec 23, 2009‎
The coroner's notes allegedly claim a pharmacopia in Murphy's bathroom cabinet: Topamax (for seizures or migraines), methylprednisolone (a steroid), ... Salon

Here's my prescription for 2010: sanity and sobriety  -  ‎Dec 28, 2009‎
Discovered on Brittany Murphy's night table (as with Ledger's gallery, one wonders who was the curator) was a wide array of pills, including Topamax, ... Globe and Mail

Drugs found in Brittany's bedroom  -  ‎Dec 23, 2009‎
There was also a packet of Propranolol; for hypertension and to prevent heart attacks, anti-seizure medication Topamax, anti-inflammatory treatment ... Stuff.co.nz

Brittany Murphy Should Be The Last Straw For Hollywood  -  ‎Dec 23, 2009‎
TMZ reports the following drugs were found in the home belonging to Brittany: Topamax (anti-seizure meds also to prevent migraines), Methylprednisolone ... Glosslip (blog)

GOLFERS TEE UP  -  ‎Dec 21, 2009‎
H57 Hoodia lipitor drug cost prednisone stopped taking side effects Topamax Weight Loss difference between lexapro and celexa! ... San Jose Magazine

Brittany Murphy CLUELESS died of drug overdose, a la Michael Jackson??  -  ‎Dec 23, 2009‎
The names of the drugs included Fluoxetine, Klonopin , Topamax , Methylprednisolone, Carbamazepinean Ativan, Vicoprofen, Propranolol etc. ... stardustco.in

Brittany Murphy Autopsy Complete, Waiting For Toxicology Results  -  ‎Dec 22, 2009‎
The amount and kind of prescriptions found in Brittany's home have been revealed including Topamax for migraines and seizures, the anti-inflammatory ... Fashion.ie

Pharmaceutical industry financial performance  -  ‎Dec 11, 2009‎
Lilly), montelukast (Singulair; Merck), clopidogrel (Plavix; Bristol–Myers Squibb/Sanofi–Aventis), valsartan (Diovan; Novartis) and topiramate (Topamax; ... Nature.com (subscription)

Whom Brittany Murphy Loved More?  -  ‎Dec 22, 2009‎
The drugs found reportedly included: Topamax (an anti-seizure med that also prevents migraines), Methylprednisolone (anti-inflammatory), ... Pravda

Brittany a 'bright light that lit the world'  -  ‎Dec 26, 2009‎
...showed a multitude of drugs were found at the starlet's home, including the anti-seizure medicine Topamax, anti-anxiety medicines Klonopin and Ativan, ... Sydney Morning Herald

Brittany Murphy's husband keeps talking  -  ‎Dec 23, 2009‎
Monjack, and according to the coroner's report multiple other names: Topamax (an anti-seizure medication also used to prevent migraines), ... SheKnows.com

Why Are We Drugging Our Kids?  -  ‎Dec 14, 2009‎
The prices for anticonvulsants can run as high as $929 for 180 tablets of Glaxo's Lamictal, and $1170 for 180 tablets of Johnson & Johnson's Topamax. ... AlterNet

Los medicamentos pudieron matar a Brittany Murphy  -  ‎Dec 23, 2009‎
Al menos Así lo aseguran médicos de reconocido prestigio en Estados Unidos. os de las medicinas, Topamax y Carbamazepina son medicamentos anticonvulsivos ... Dminorias

Lo último de la muerte de Brittany Murphy, todo apunta a sobredosis  -  ‎Dec 22, 2009‎
Los medicamentos incluyended the anti-seizure medication Topamax, anti-anxiety medications Klonopin and Ativan, pain relievers Vicoprofen and hydrocodone, ... SonFamosos.com

Brittany Murphy : elle était une pharmacie ambulante !  -  ‎Dec 23, 2009‎
Selon TMZ, les enquêteurs ont répertorié une liste de pilules : du Topamax (un médicament qui prévient les convulsions et qui traite aussi la migraine), ... Closer

Brittany Murphy: morta per influenza A o overdose da farmaci?  -  ‎Dec 26, 2009‎
Degno di nota è stato anche il ritrovamento del medicinale Topamax, utilizzato per curare l'emicrania, ma anche per prevenire gli infarti. ... Notizie Fresche

Le Qnexa et le Lorcaserin, médicaments pour la perte de poids, soumis à la FDA  -  ‎Dec 29, 2009‎
Ce médicament est une combinaison de phentermine (dérivé de l'amphétamine, utilisé pour réduire l'appétit) et de topiramate (Topamax, un antiépileptique). ... PsychoMédia

Бриттани Мерфи любила таблетки  -  ‎Dec 23, 2009‎
Среди медикаментов полициÑ? нашла, в чаÑ?тноÑ?ти, препарат против мигрени Topamax, антидепреÑ?Ñ?ант Fluoxetine, уÑ?покоительные Klonopin, Ativan, ... Sutki.net

Realizarán hoy sepelio de Brittany Murphy bajo estricta seguridad  -  ‎Dec 24, 2009‎
Algunos de los que ingería son: Topamax, Metilprednisolona, Fluoxetina, Klonopin, Carbamazepina, Ativan, Vicoprofen, Propranolol, Biaxin y Hidrocodona. ... El Financiero (México)

Brittany Murphy  -  ‎Dec 22, 2009‎
...os ansiolíticos Klonopin e Ativan, o anticonvulsivo Topamax, o analgésico Hidrocona, o contra hipertensão Propranolol, além de suplementos vitamínicos. ... Contigo!

Brittany Murphy: ses funérailles auront lieu ce jeudi  -  ‎Dec 24, 2009‎
De nombreux médicaments ont été retrouvés dans la chambre à coucher de l'actrice dont du Topamax (un médicament qui prévient les convulsions et qui traite ... Showbizz.net

Funeral de Brittany Murphy terá esquema de segurança, diz site  -  ‎Dec 24, 2009‎
Hydrocodone), antibióticos (Biaxin), antidepressivos (Fluoxetine), além de um antiepilético também usado para combater dores de cabeça (Topamax), ... G1.com.br

Brittany Murphy: qua medicijngebruik Michael Jacksons…  -  ‎Dec 22, 2009‎
Topamax (tegen migraine), Methylprednisolone (tegen maagzuur), Fluoxetine (anti-depressivum), Klonopin (angstremmer), Carbamazepine (voor diabetici en ... Blog.nl (Blog)

Tutte le droghe di Brittany Murphy Via locandina dvd con l'attrice morta  -  ‎Dec 28, 2009‎
Topamax, Fluoxitina, Metilprednisolone, Ativan, Vicoprofen, Propanol e molte altre. La maggior parte sono usate per la perdita di peso, ... TGCOM

Brittany Murphy – Tod wirft weiter Rätsel auf  -  ‎Dec 22, 2009‎
Aus den Dokumenten der Ermittler gehe hervor, dass sich viele verschreibungspflichtige Medikamnte in Brittanys Nachttisch befunden haben, darunter Topamax ... Viply

Murphy: Schweinegrippe & Pillenmix?  -  ‎Dec 22, 2009‎
In ihrem Schlafzimmer fanden die Ermittler beträchtliche Mengen verschreibungspflichtiger Medikamente: Topamax (gegen Krämpfe und Migräne), ... oe24.at

Noi informaÅ£ii în cazul Brittany Murphy  -  ‎Dec 23, 2009‎
Însă după raportul legistului (obţinut de TMZ.com), medicaţia confiscată de procurori conţinea Topamax - un medicament împotriva atacurilor cerebrale, ... Cinemagia

Brittany Murphy kan ha dött av en överdos, precis som skÃ¥despelaren Heath Ledger.  -  ‎Dec 22, 2009‎
...epilepsi och mot bipolära syndrom), Antivan (ångestdämpande), Vicoprofen (smärtstillande), Hydrocodone (smärtstillande), Topamax (diabetesmedicin som ... Aftonbladet

Brittany, l'autopsia non basta Tanti farmaci, niente droghe  -  ‎Dec 22, 2009‎
Tra queste alcune erano relative al Topamax (un medicinale contro gli infarti usato pure per curare le emicranie), all'anti-infiammatorio Methylprednisolone ... Libero News

Teorija: Murphy mirÄ— perdozavusi vaistų  -  ‎Dec 22, 2009‎
Kaip rašoma tyrėjų ataskaitoje, rastų vaistų pavadinimai yra šie: „Topamax“ (vaistai nuo infarkto, taip pat padedantys nuo migrenos), „Methylprednisolone“ ... Alfa.lt

Teva Pharmaceutical Industries Limited - Financial And Strategic Analysis ...  -  14 Nov 2009
In 2009, the company launched Topamax Tablets, Adderall XR and Generic Urso 250. It also received approval of Risperdal oral solution, Copaxone and Imitrex ... OfficialWire (press release)

J&J to Slash 7000 to 8000 Jobs  -  ‎Nov 3, 2009‎
Cost savings have helped J&J cope with plunging sales of Risperdal and Topamax and to acquire stakes this year in Irish drugmaker Elan Corp and Dutch ... ABC News

Band-Aid Won't Stop Generic Bleeding at Johnson & Johnson  -  ‎Nov 11, 2009‎
In the latest third quarter, sales of Topamax declined 88 percent to $72 million! Risperdal experienced a similar fate following the June 2008 US patent ... BNET

Trial Ordered in Anna Nicole Smith's Death  -  ‎Nov 2, 2009‎
...told Perry that they thought Smith was addicted to a variety of opiates and sedatives, including Valium, methadone, Xanax, Topamax and Soma. ... Courthouse News Service

Pfizer to cut jobs at Wyeth's Montco site  -  ‎Nov 10, 2009‎
Development LLC employed 680 in Spring House, where the company said prescription medicines, including Topamax, Ultram, and Ultracet, were developed. ... Philadelphia Inquirer

Larry Birkhead Testifies In Anna Nicole Case  -  ‎Oct 19, 2009‎
When asked about the drugs he could recall Anna Nicole indulging in, he replied with a list: “Topamax, Klonopin, Lasix, Valium and some sort of potassium ... PerezHilton.com (blog)

J&J to cut 174 Montco jobs  -  ‎Nov 9, 2009‎
Development LLC employed 680 in Spring House, where the company said prescription medicines, including Topamax, Ultram and Ultracet, were developed. ... Philadelphia Inquirer

At Johnson & Johnson, Merger-style Savings  -  ‎Nov 4, 2009‎
For example, sales of the migraine treatment Topamax fell to $175 million in the third quarter this year, from $728 million last year. ... New York Times (blog)

Judge orders Anna Nicole Smith's doctors, boyfriend to stand trial  -  ‎Oct 30, 2009‎
...the anti-seizure medication Topamax, the muscle relaxant Soma, the sedative chloral hydrate and Dilaudid, a painkiller nicknamed "hospital heroin. ... Los Angeles Times

Additional Data from the Qnexa Phase 3 Studies Presented at The Obesity ...  -  ‎Oct 29, 2009‎
This rate is considerably lower than the similar event rates reported in the Topamax® (topiramate) label. The label for Topamax for the prevention of ... Reuters

Cadila Healthcare extends gains on healthy Q2 numbers  -  ‎Oct 28, 2009‎
The drug is the generic version of Ortho McNeil's Topamax capsules. The drug is used for treating migraine headaches in adults. The drug had total sale of ... India Infoline.com

Headache treatments  -  ‎Oct 19, 2009‎
Persistent migraines can be treated with preventive medications that include Topamax and Elavil. People who experience infrequent migraines can be treated ... Reading Eagle

Personal Health The Many Ills of Peripheral Nerve Damage  -  ‎Oct 20, 2009‎
Many with neuropathic pain have benefited from drugs licensed for other uses, including antiseizure medications like gabapentin, topiramate (Topamax) and ... New York Times

Forecast Insight - Migraine - Generic incursion inhibits market growth ...  -  ‎Oct 23, 2009‎
Led by the seven triptan brands and Topamax´s (topiramate; Johnson & Johnson) continued uptake, seven major market migraine revenues grew strongly at an ... PR-Inside.com (Pressemitteilung)

A Shopper's Guide To Use Of Generic Drugs  -  ‎Nov 2, 2009‎
The Medical Letter cites the following study: “Another retrospective cohort study found that generic substitution of topiramate (Topamax, and others) was ... Philadelphia Bulletin

Justice eyes marketing at J&J, Forest  -  ‎Nov 10, 2009‎
...related primarily to the marketing of antipsychotic Risperdal, as well as the seizure drug Topamax and congestive heart failure remedy Natrecor. ... FiercePharma

For dividends, diversification, look beyond Canada  -  ‎Nov 9, 2009‎
...schizophrenia medication Risperdal and the epilepsy treatment Topamax, which contributed to a 5.3-per-cent drop in third-quarter revenue. ... Globe and Mail

Is Your Medication Making You Sick?  -  ‎Nov 9, 2009‎
However, researchers at Thomas Jefferson University have successfully used the migraine-prevention drug Topamax to wean medication overuse headache ... MSN Health & Fitness

Smith & Nephew Q3 Profit Rises - Update  -  ‎Nov 6, 2009‎
...despite a 5.3% downturn in sales, as weak sales of its prescription drugs Topamax and Risperdal were negatively impacted by generic competition. ... Trading Markets (press release)

Top CNS Portfolios - The Industry Gold Standards  -  ‎Oct 21, 2009‎
The company performs well in all three sectors of CNS with blockbuster products in each; namely Risperdal (psychiatry), Duragesic (pain), and Topamax ... PRMinds (press release)

Diet pills: Vivus, Arena and Orexigen in race to market safe weight-loss drugs  -  ‎Oct 28, 2009‎
Vivus' drug is also a combo therapy that mixes the other generic drug in the fen-phen combo, phentermine, with the generic topiramate, sold as Topamax by ... Daily Finance (blog)

Pfizer Q3 Profit Climbs, Beats Estimates; Lifts FY09 Forecast On Wyeth Deal ...  -  ‎Oct 20, 2009‎
Meanwhile, the New Brunswick, New Jersey-based company's sales fell 5.3% to $15.1 billion on weak sales of its prescription drugs Topamax and Risperdal, ... Trading Markets (press release)

Ahead Of Boston Scientific Q3 Results  -  ‎Oct 19, 2009‎
Meanwhile, the New Brunswick, New Jersey-based company's sales fell 5.3% to $15.1 billion on weak sales of its prescription drugs Topamax and Risperdal, ... Trading Markets (press release)

“Like a miracleâ€?  -  ‎Nov 4, 2009‎
He treats patients with the singular injection of magnesium and then prescribes a low dose of Topamax. In some cases, Elliott said he'll also talk with ... Niles Daily Star

HEALTH CARE AND MIGRAINES  -  ‎Oct 26, 2009‎
These include propranolol (Inderal®), timolol (Blocadren®), topiramate (Topamax®) and divalproex sodium (Depakote®). These have had many years of use and ... The Cypress Times

Biotech Company Buyouts  -  ‎Oct 22, 2009‎
Specifically, sales of Topamax and Risperal fell 88 percent and 71 percent respectively, as their patents expired. That may be why JNJ bought an 18 percent ... Wealth Daily

Sandoz introduces two new generic drugs  -  ‎Oct 20, 2009‎
According to the news source, the company has launched topiramate sprinkle capsules, a generic version of Johnson & Johnson's epilepsy drug Topamax Sprinkle ... Trading Markets (press release)

Sleepers, Awake!  -  ‎Oct 27, 2009‎
Risperdal, phenothiazines, Vestra, Restoril, Melleril, Thorazine, Topamax, Halcion, Depakote, Toprol, Remeron, Wellbutrin, Sonata, Zyban, and Zyprexa. Psychology Today (blog)

Qnexa Diet Pill VIDEO  -  ‎Oct 25, 2009‎
It combines “the good half of the infamous Fen-Phen� aka the part that didn't lead to heart ailment and Johnson & Johnson's Topamax. Topamax is prescribed ... China dgshi News (blog)

嬌生è£?å“¡8200å??  -  ‎Nov 4, 2009‎
...嬌生的精神科藥物「ç?†æ€?必妥ã€?(Risperdal)的專利權在去年到期,該公å?¸æŠ—癲癇和å??頭痛的藥物Topamax,從3月起也開始é?¢è‡¨é?žå°ˆåˆ©è—¥ç‰©çš„競爭。 橫跨藥å“?ã€?醫療器æ??和消費 ... 中時電子報

USA: Johnson&Johnson zwolni do 8 tysiÄ™cy pracowników  -  ‎Nov 3, 2009‎
Specyfiki, których sprzedaż spadła, to między innymi podawany schizofrenikom Risperdal i używany w leczeniu padaczki Topamax. Onet.pl

娇生è£?撤全ç?ƒ6-7%员工,望明年å‰?节çœ?9亿美元æˆ?本支出  -  ‎Nov 3, 2009‎
...娇生出产处方è?¯åŒ…括精神分裂症è?¯ç‰©Risperdal和治疗癫痫的Topamax等等。 董事兼执行长WilliamC.Weldon在公开谈è¯?时指出:「娇生长久以æ?¥ï¼Œä¸€ç›´ä¿?æŒ?广泛的基础业务模å¼?, ... 腾讯网

强生拟è£?撤数å?ƒä¸ªè?Œä½? 为研å?‘ç»?费谋求财æº?  -  ‎Nov 3, 2009‎
Weldon指出,这项组织调整预计影å“?的层é?¢å¤šæ•°åœ¨æµ·å¤–,但并é?žå› åº”美国医ä¿?改é?©,å’Œé?žä¸“利è?¯å¯¹å…¶Risperdal精神分裂è?¯ç‰©ã€?Topamax癫痫疗法构æˆ?的新竞争,æ‰?å?šå‡ºçš„å??应. ... 路透社

强生:è£?员7000人  -  ‎Nov 12, 2009‎
...这主è¦?是因为两款é‡?è¦?è?¯å“?癫痫è?¯ç‰©Topamax以å?ŠæŠ—ç²¾ç¥žç—…è?¯ç‰©Risperdal专利到期。上个财年,这两款è?¯ç‰©å¸¦æ?¥äº†çº¦70亿美元的销售é¢?,而专利到期ã€?窥视已久的仿制è?¯ä¸€å“„而上 ... 网易 (博客)

美国股市13日早盘走低  -  ‎Oct 27, 2009‎
...强生表示,处方è?¯è?¥æ”¶å‡?少逾14%,因其抗癫痫è?¯Topamax和抗精神病è?¯Risperdal专利过期引å?‘竞争。 北京时间22:20,é?“ç?¼æ–¯å·¥ä¸šæŒ‡æ•°ä¸‹è·Œ48.07点,报9, 837.73点;纳斯达克 ... 易富网

Tire 20 dúvidas sobre métodos para evitar a gravidez  -  ‎Nov 9, 2009‎
Anticonvulsivantes: alguns deles, incluindo fenitoína (Dilantin®), carbamazepina (Tegretol®), barbitúricos, primidona (Lamictal®), topiramato (Topamax®) e ... Terra Brasil

Johnson & Johnson Bakal Pangkas 7.000 Karyawan  -  ‎Nov 3, 2009‎
Penurunan penjualan didorong oleh rendahnya permintaan konsumen terhadap produk obat-obatan generik, antipsikotik Risperdal, dan obat epilepsi Topamax. ... KOMPAS.com

Media Vest  -  ‎Oct 22, 2009‎
Continental Airlines, Laboratorios Janssen Cilag (Evra, Vermox, Topamax), Richemont (Montblanc, Cartier, Baume et Mercier), The Topps Company (Ring pop, ... Terra México

Topamax May Raise Risk of Birth Defects  -  Jul 21, 2008
...(WebMD) The epilepsy and migraine prevention drug Topamax has been linked to an increased risk of birth defects in babies born to epilepsy patients who took ... CBS News

J&J: Court bars Mylan sale of generic Topamax to '08  -  Mar 22, 2007
NEW YORK, March 22 (Reuters) - A US court has permanently enjoined Mylan Laboratories Inc. MYL.N from selling a generic version of Johnson & Johnson's (JNJ. ... Reuters

Appeals court backs Ortho-McNeil in Topamax fight  -  Mar 31, 2008
WASHINGTON, March 31 (Reuters) - A federal appeals court on Monday upheld a ruling that prevents generic drug maker Mylan MYL.N from pursuing efforts to ... Reuters

New Drug May Treat Alcoholism Without Detox  -  Oct 9, 2007
The drug, Topamax, works in a different way than three other medications already approved ... About half were randomly assigned to take Topamax, also called ... FOXNews

J&J gets exclusivity period on Topamax extended  -  Jul 24, 2008
NEW BRUNSWICK, NJ --Johnson & Johnson's neurologics unit said Thursday a Food and Drug Administration decision will extend the patent on its epilepsy ... Boston Globe

Study finds Topamax/kidney-stone link  -  Oct 31, 2006
DALLAS, Oct. 31 (UPI) -- The anti-seizure drug Topamax -- also taken for migraines -- appears to raise the risk of kidney stones, US researchers said ... United Press International

US judge sides with J&J in Topamax patent dispute  -  Feb 13, 2007
CHICAGO, Feb 13 (Reuters) - A federal judge in New Jersey ruled in favor of Johnson & Johnson (JNJ.N) in a dispute over its patent for epilepsy drug Topamax ... Reuters

FDA orders suicidal action warning on epilepsy drugs  -  Dec 17, 2008
Topamax already includes information about suicidal behavior in its prescribing instructions, said Tricia Geoghegan, a spokeswoman for J&J unit Ortho-McNeil ... Reuters India

Migraine pill helps alcoholics taper off drinking  -  Oct 10, 2007
About half were randomly assigned to take Topamax in gradually increasing doses. ... The Topamax group cut back to six drinks a day, on average, ... 新�网

Johnson & Johnson profit rises 9%  -  Oct 17, 2006
Global Topamax sales also rose 24%, to $533 million, while combined sales of Risperdal and the injectable long-acting Consta version of the medicine rose ... USA Today

J&J to Cut Up to 4,820 Jobs on Drug Woes  -  Jul 31, 2007
Topamax had 2006 sales of about $2 billion. During the second quarter, sales of J&J's key anemia drug Procrit, formerly the company's best-selling drug, ... FOXNews

US orders suicidal action warning on epilepsy drugs  -  Dec 16, 2008
Topamax already includes information about suicidal behavior in its prescribing instructions, said Tricia Geoghegan, a spokeswoman for J&J unit Ortho-McNeil ... Forbes

Mylan Dealt Court Setback | Pharmaceuticals News | Print Financial & ...  -  Oct 24, 2006
In addition to being used for epilepsy, Topamax is also prescribed to prevent migraine headaches in adults. Its patent expires in September 2008. TheStreet.com - TheStreet.com (subscription)

J&J migraine drug helps some alcoholics cut binges  -  Oct 10, 2007
The study was funded by Johnson & Johnson, which makes Topamax, or topiramate ... Researchers tested Topamax in 371 men and women aged 18 to 65 with alcohol ... Reuters India

FDA approves new indication for Topamax for adults and children with ...  -  Jul 1, 2005
The US Food and Drug Administration (FDA) yesterday approved a new use for TOPAMAX (topiramate) Tablets and TOPAMAX (topiramate capsules) Sprinkle Capsules ... Medical News Today - Medical News Today (press release)

… to Reported Medication Errors Between TOPAMAX(R) (topiramate) and ...  -  Oct 2, 2005
Ortho-McNeil Neurologics, Inc., is launching an educational campaign to alert health care professionals to the potential for medication errors between its ... Medical News Today - Medical News Today (press release)

J&J profit jumps, boosted overseas by weak dollar  -  Jan 22, 2008
Topamax sales grew 23 percent to $652 million, helped by increasing use of the medicine to also treat migraine headaches. Sales of anemia medicines Eprex ... Reuters

US court rejects Mylan appeal in Topamax patent case  -  Apr 12, 2007
WASHINGTON, April 12 (Reuters) - A US appeals court on Thursday dismissed an appeal by Mylan Laboratories Inc. MYL.N of a lower court judge who barred Mylan ... Reuters

… to Reported Medication Errors Between TOPAMAX(R) and TOPROL-XL( …  -  Sep 27, 2005
TOPAMAX is approved by the US Food and Drug Administration (FDA) for epilepsy treatment and ... Reports of patients receiving TOPAMAX instead of TOPROL-XL, ... $4.95 - PR Newswire - ECNext

FDA Approves Mylan's Generic Topamax  -  Sep 12, 2006
Mylan said Tuesday the US Food and Drug Administration approved its generic formulation of Ortho-McNeil's migraine medication Topamax. ... RedOrbit

J&J hit with new batch of subpoenas  -  Mar 13, 2007
Topamax became the focus of an inquiry in 2003 by federal prosecutors in Boston ... Topamax revenues were $2 billion last year. Johnson & Johnson doesn't ... San Francisco Chronicle

People's Pharmacy: Help for fungal infections  -  Dec 14, 2008
Q. Does Topamax cause complete lack of sexual desire? A. Topamax (topiramate) is prescribed for epilepsy, but it also is used to prevent migraine headaches. ... Houston Chronicle

… Medicines Consortium (SMC) Approves Topamax(R) For Prevention Of …  -  Sep 14, 2006
A significant new treatment option to prevent migraine headaches is now available in Scotland following Monday's approval of TOPAMAX(R) (topiramate) by The ... Medical News Today - Medical News Today (press release)

Push to prevent epilepsy after brain injury - More health news-...  -  Apr 3, 2007
Among the efforts: pilot studies to see if the newer seizure-treating drugs Topamax or Keppra might actually prevent epilepsy if they're taken immediately ... msnbc.com

RPT India's Lupin says gets tentative FDA approval for Topiramate...  -  May 30, 2008
Topiramate tablets are the generic equivalent of Ortho-McNeil's Topamax tablets, used for the treatment of seizures. Lupin said the drug is expected to be ... Forbes

J&J's Profit Rises on Drug, Medical Devices Sales  -  Jan 23, 2007
Sales of Topamax also gained from the new Medicare program, Biegelsen said. ... Risperdal had global sales of $1.1 billion in the quarter, and Topamax had ... Bloomberg

FDA approves new indication for Topamax for adults and children with ...  -  Jul 4, 2005
The US Food and Drug Administration (FDA) yesterday approved a new use for TOPAMAX (topiramate) Tablets and TOPAMAX (topiramate capsules) Sprinkle Capsules ... i-newswire.com

Topamax(R) Reduces Number Of Monthly Migraine Days In Chronic …  -  Apr 30, 2006
A study presented today at the annual meeting of the 8th European Headache Federation (EHF) demonstrated that chronic migraine sufferers treated ... Medical News Today - Medical News Today (press release)

Topamax May Raise Risk of Birth Defects  -  Jul 21, 2008
French tells WebMD that the study was too small to accurately assess the risk to babies born to mothers who take Topamax alone. ... WebMD

Acomplia Report - Development of Topamax for Obesity Halted  -  Nov 8, 2005
Johnson and Johnson announced it is discontinuing its current clinical development program for a time-release formulation of Topamax (topiramate) for use in ... Acomplia Report

… to Reported Medication Errors Between TOPAMAX(R) and TOPROL-XL(  -  Sep 27, 2005
TOPAMAX is approved by the U.S. Food and Drug Administration (FDA) for epilepsy treatment ... Reports of patients receiving TOPAMAX instead of TOPROL-XL, ... Pay-Per-View - PR Newswire - HighBeam Research

Vivus says obesity drug leads to 9 pct weight loss  -  Dec 11, 2008
Qnexa is a combination of phentermine -- half of the recalled fen-phen diet pill -- and the epilepsy drug Topamax, or topiramate. ... Reuters

Driver charged in hitting cyclist  -  Apr 28, 2006
Trooper Jeanne Martin said. Lab tests later found traces of marijuana and the anti-seizure medicine Topamax in Ms. Holland's system. Pittsburgh Post-Gazette - Pittsburgh Post Gazette

Order Topamax COD  -  May 21, 2007
...to fall within a range in which the drug produces a therapeutic effect or desired outcome.[1] The safety and effectiveness Order Topamax COD prescription ... Sokwanele

Promise of Topamax(R) in Prevention of Migraine Episodes, New Long …  -  Sep 21, 2005
Results from two large clinical trials demonstrate that patients with frequent migraine who were treated with TOPAMAX(R) (topiramate) for up to 14 months (6 ... Medical News Today - Medical News Today (press release)

Prevention of migraine episodes, Topamax shows promise - New long- …  -  Sep 28, 2005
Results from two large clinical trials demonstrate that patients with frequent migraine who were treated with TOPAMAX® (topiramate) for up to 14 months (6 ... Medical News Today - Medical News Today (press release)

Scientists Seek Early Interventions For Epilepsy  -  Apr 4, 2007
Among the efforts: pilot studies to see if the newer seizure-treating drugs Topamax or Keppra might actually prevent epilepsy if they're taken immediately ... Wired News

Topamax and weight loss  -  Jan 27, 2008
Hello,My name is Julie; I am 35 years old, and I've been suffering from migraines since I was about 14 years old. My doctor put me on topamax about 7 months ... HealthCentral.com

Sperling's BestPlaces Uncovers Migraine 'Hot Spots' In The US  -  Mar 11, 2006
TOPAMAX Tablets and Sprinkle Capsules, approved for the prevention of migraine headaches ... In clinical studies with TOPAMAX , many people with migraine ... Medical News Today - Medical News Today (press release)

Troops who return from war with battered bodies and minds are …  -  Aug 26, 2008
Spending for Topamax, an epilepsy medicine now being used to treat soldiers ... Some experts question the wisdom of prescribing Topamax widely to soldiers. ... $1.95 - Denver Post - NewsBank

Prescription drug mix-ups prompt FDA admonition  -  Sep 28, 2005
Topamax, also known as topiramate, which is used to treat epilepsy and to prevent migraines. It is made by Ortho-McNeil Neurologics Inc. ... $2.95 - Kansas City Star - NewsBank

Anna Nicole Smith, Topamax, Methadone, Elvis, & Karma  -  Mar 7, 2007
The news has been plentiful and redundant lately with stories about Anna Nicole Smith's life and death. Stories about her baby and who the father might be, ... HealthCentral.com

Help for Migraines (Topomax)  -  May 22, 2006
1 Topamax, (topiramate) an antiepileptic drug, is indicated for migraine ... 3 In two studies of more than 300 patients, Topamax reduced the average number ... ADVANCE

Topiramate (generic): Topamax (brand).(YOUR MEDICATION …  -  Oct 1, 2005
COMMON USAGE: Topiramate is indicated as adjunctive therapy for the treatment of adults and children ages 2 to 16 with partial onset seizures, ... Free with registration - Brown University Psychopharmacology... - AccessMyLibrary.com

Topiramate (Topamax): Dosage, Side Effects, and Interactions  -  Oct 29, 2007
Topiramate is taken several times each day. Topiramate comes in tablets and capsules, which can be opened and sprinkled on food. ... WebMD

Daily Migraines on Topamax, verapamil, and Cymbalta?  -  Jul 11, 2008
I get daily migrains. I am on !25 mgs of Topaamx, 520 mgs of Verapamil,and 60 mgs of cymbalta. I also take releplex or frova when the paim starts. ... HealthCentral.com

… -Time Generic Approvals: Seasonale, Imodium Advanced, and Topamax  -  Sep 22, 2006
September 22, 2006 — The US Food and Drug Administration (FDA) has approved first-time generic formulations of ciprofloxacin levonorgestrel plus ethinyl ... Medscape

… NOTED: Canada drafting bulk drug rules; Topamax approved for new …  -  Jun 29, 2005
...> As expected, Canadian health officials say they have begun to draft new regulations that would stop bulk drug shipments going south. ... FierceBiotech

Topamax No Prescription  -  Oct 9, 2007
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… : FDA Grants Pediatric Exclusivity for TOPAMAX(R), Extending the …  -  Jul 24, 2008
FDA Grants Pediatric Exclusivity for TOPAMAX(R), Extending the Marketing Exclusivity by Six Months. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

Topamax and anti depressants  -  Jun 27, 2007
I've been reading all the posts about Topamax, and they all seem negative. I get severe nausea and vomiting with my migraines. My doctor prescribed it to me ... HealthCentral.com

8/20/07 #4 - Altered taste, tingling due to Topamax?  -  Aug 20, 2007
I have been taking Topamax for three months and I am experiencing a difference in the way my food tastes, an awful metallic taste in my mouth, and painful, ... HealthCentral.com

Topamax & Pregnancy  -  Oct 29, 2007
Hi all, I recently got started on Topamax and am on 25 mg/day and will up it to 50mg/day tomorrow and doc wants me to go up to 100mg/day. ... HealthCentral.com

Discount Topamax COD  -  May 5, 2007
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New to to Topamax and Migranes (kinda) are these side effects? or is...  -  Aug 20, 2007
New to to Topamax and Migranes (kinda) are these side effects? or is it something else? OK, I have been having migraines for years off and on but nothing to ... HealthCentral.com

Topamax Overnight Delivery  -  Jul 14, 2007
...sale, and administration of Topamax Overnight Delivery In the United States Pharmacopoeia.In the European Pharmacopoeia. Pharmacology as a chemical science ... Sokwanele

Buy Topamax COD  -  May 13, 2007
...on specific cellular signalling pathways controlling cellular function). A chemical has, from Buy Topamax COD pharmacological point-of-view, ... Sokwanele

New drug option for migraine sufferers  -  Dec 3, 2007
Topamax will be subsidised from today under the PBS for migraine sufferers. ... Topamax, which is also used in the treatment of epilepsy, ... The Australian

Johnson & Johnson set to give 4,800 the boot  -  Aug 1, 2007
Topamax has annual sales of about $2 billion. Johnson & Johnson shares rose 43 cents to $60.50, still near their 52-week low of $59.72. ... New York Daily News

Study: Migraine drug may boost kidney stone risk  -  Nov 10, 2006
November 10, 2006 (WLS) -- The drug Topamax is commonly prescribed to treat ... The short-term use of Topamax did not increase the risk of kidney stones. go.com

Topamax Seizure Medication  -  Dec 27, 2007
Find out which seizure medication is right for you. Everything you must know regarding interaction with other medications. Pros and cons of the most widely ... Buzzle

… topiramate tablets and sprinkle capsules (Topamax, Ortho-McNeil)...  -  Aug 1, 2005
FDA approved topiramate tablets and sprinkle capsules (Topamax, Ortho-McNeil) as initial monotherapy in patients aged 10 years and older with partial-onset ... Free with registration - Formulary - AccessMyLibrary.com

Epilepsy Drug May Cause Birth Defects  -  Jul 27, 2008
The new study was one of the first to link Topamax to an increased risk of birth ... The mother's studied were taking Topamax for epilepsy treatment. ... HealthNews

Migraine pill aids alcoholics, research finds  -  Oct 10, 2007
Topamax works in a different way than three medications approved for treating alcoholism. Experts said the drug is likely to appeal to heavy drinkers who ... Pay-Per-View - Orlando Sentinel - ProQuest Archiver

Alcohol Abuse and Dependence - Medications  -  Feb 15, 2008
Topiramate (Topamax), a medicine used to treat seizures. One recent study shows that it also might help treat alcohol problems. 6 Experts are studying how ... WebMD

FDA Grants Pediatric Exclusivity For TOPAMAX®  -  Jul 26, 2008
Ortho-McNeil Neurologics, a division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., announced that the US Food and Drug Administration (FDA) has granted ... Medical News Today - Medical News Today (press release)

FDA Approvals: Aptivus, MetroGel, Topamax  -  Jul 21, 2005
July 21, 2005 — The US Food and Drug Administration (FDA) has approved tipranavir capsules for coadministration with low-dose ritonavir as part of ... Medscape

topamax preventive medication  -  May 26, 2008
...does anyone have experience with topamax and do you have to take it for the rest of your life or can you stop after a half year or so and are your migraines ... HealthCentral.com

11 year old started on topamax at 150mg first day and 100mg thereafter...  -  Jul 28, 2008
...my 11 year old was started on topamax at 150mg divided into 3 doses and then she got 100mg a day x4 days and then due to so many side effects we began to ... HealthCentral.com

TOPAMAX AND HYPOGLYCEMIA  -  Nov 15, 2007
I have been having migraines for about 5 years now and finally decided to go the doctor now that they are lasting 3+ days. Well, the doctor said it was ... HealthCentral.com

Topamax and Vitamin Therapy  -  May 9, 2008
Hi Everyone!!! I have been battling migraines off and on for a long time. But just recently I have been having consistent headaches every single day for the ... HealthCentral.com

Mylan Announces Tentative Approval for Generic Topamax Capsules  -  Sep 19, 2007
Mylan Pharmaceuticals has received tentative FDA approval for its abbreviated new drug application for generic Topamax 15- and 25-mg capsules, ... FDA news - FDA news (subscription)

Topiramate (Topamax) Beneficial for a Wide Range of Alcohol's Effects  -  Jun 10, 2008
By Todd Neale, Staff Writer, MedPage Today. CHARLOTTESVILLE, Va., June 10 -- In addition to reducing heavy drinking, patients taking topiramate (Topamax) ... MedPage Today

My first experience on Topamax  -  May 29, 2007
I just wanted to share my experiences on Topamax that I have been taking for 4 weeks now. So many people have been having bad side effects on this ... HealthCentral.com

Brand Names/Synonyms:
Topamax is also known by the following brand names and/or synonymsCHEMBANK1823; Mcn-4853; Tipiramate [French]; Tipiramato [Spanish]; Topamax; Topamax Sprinkle; Topiramate; Topiramate [Usan:Ban:Inn]; Topiramato [Inn-Spanish]; Topiramatum [Inn-Latin]; Topiramatum [Latin]

Drug Category:
Topamax is categorized under the following by the FDA: Antiobesity Agents; Neuroprotective Agents; Anticonvulsants; ATC:N03AX11

Dosage Forms:
CAPSULE; TABLET

Absorption:
Rapid with pleak plasma concentrations occurring after 2 hours. Bioavailability is 80%

Interactions:
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Chemical IUPAC Name:
2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate





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