Torasemide

This page contains recent news articles, when available, and an overview of Torasemide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Torasemide (when available)

Pharmacology and use:
Torasemide, a monosulfonamyl loop diuretic, differs form other thiazide diuretics in that a double ring system is incorporated into its structure. Torasemide is used alone or with atenolol in the management of hypertension and edema. Micropuncture studies in animals have shown that torsemide acts from within the lumen of the thick ascending portion of the loop of Henle, where it inhibits the Na+/K+/2CI--carrier system. For the treatment of hypertension, edema induced by congestive heart failure or renal disease and ascites assocated with hepatic disease

Mechanism Of Action:
Torasemide acts on the Na+/K+/2Cl- co-transporter. It inhibits sodium ion transport across the renal tubular epithelium in the cortical diluting segment of the ascending limb of the loop of Henle. By increasing the delivery of sodium to the distal renal tubule, Torasemide indirectly increases potassium excretion via the sodium-potassium exchange mechanism

News Articles on Torasemide

China Biopharmaceuticals Announces Robust Progress in Its Drug …  -  Nov 7, 2006
The clinical trials for Torasemide for injections and tablets were conducted ... Torasemide is a loop diuretics. It is commonly used in conditions such as ... Genetic Engineering News - Genetic Engineering News (press release)

“고혈압약 드시는 분, �?�런 �?��?�?� 피하세요�?  -  Dec 2, 2008
...�?�다파미드(Indapamide), 메톨�?�존(Metolazone) 등 '치아짓계 �?�뇨제'와 △푸로세 미드(Furosemide), 아조세미드(Azosemide), 토�?�세미드(Torasemide) 등 '루프계 ... 아�?�비타임즈

"CCB 복용, �?몽주스 주�?�하세요"  -  Dec 23, 2008
...�?�다파미드(Indapamide), 메톨�?�존(Metolazone) 등 '치아짓계 �?�뇨제'와 △푸로세 미드(Furosemide), 아조세미드(Azosemide), 토�?�세미드(Torasemide) 등 '루프계 ... 아�?�비타임즈

Loop Diuretic Dose Associated With Mortality in Patients With...  -  Jun 12, 2007
Of the 73% of patients on loop diuretics, this divided as 60% on furosemide (mean dose, 53 mg/day) and 13% on torasemide (mean dose, 7.4 mg/day). ... DG News

Meda Acquires Product Portfolio From Roche  -  Aug 15, 2008
Torem (torasemide) is a loop diuretic. It is also marketed using trademarks such as Demadex,Dilutol and Toradiur in more than 30 countries - also in the USA ... RedOrbit

Angiology; Dual thromboxane A2 inhibitors modulate angiogenesis  -  Oct 24, 2006
This study was undertaken to characterize the antiangiogenic properties of a series of original dual (TXA2) inhibitors derived from torasemide, ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Washington Administrative Code - WAC 260-70-680 This section …  -  Mar 17, 2006
Tiaprofenic Acid Surgam Timolol Blocardrin Tolazoline Priscoline Tolmetin Tolectin Torsemide (Torasemide) Demadex Trandolapril (and metabolite, ... Pay-Per-View - Washington Administrative Code - Loislaw

Swiss pharma major Roche has sold four of its established products to...  -  Sep 8, 2008
Meda has acquired worldwide rights to the anticoagulant Marcoumar (phenprocoumon); loop diuretic Torero (torasemide); NSAID Tilcotil (tenoxicam); ... Pay-Per-View - Chemistry and Industry - HighBeam Research

Diuretici dell'ansa e perdita di massa ossea in uomini anziani  -  Dec 9, 2008
Sono stati considerati utilizzatori dei diuretici dell'ansa i pazienti che stavano assumendo furosemide, bumetanide (*) o torasemide. ... Pillole.org

B형•C형 간염바�?�러스 등 위험요소 예방 최선  -  Oct 24, 2008
...비슷한 약리작용�?� 가졌지만 작용시간�?� 긴 torasemide를 furosemide 용량�?� 1/4로 대체 사용할 수 있다. ▷난치성 복수 환�?�?서 반복�?�?� 대량 복수 천�?를 시행할 ... 디지틀보사

Brand Names/Synonyms:
Torasemide is also known by the following brand names and/or synonymsAC 4464; CCRIS 6736; Demadex; JDL 464; Luprac; TORSEMIDE; Torasemida [Inn-Spanish]; Torasemide; Torasemidum [Inn-Latin]; Torsemide; Torsemide [Usan]

Drug Category:
Torasemide is categorized under the following by the FDA: Diuretics; Antihypertensive Agents; ATC:C03CA04

Dosage Forms:
LIQUID; TABLET

Absorption:
Bioavailability is ~80%, serum concentration peaks after ~1 hour

Interactions:
Not Available

Chemical IUPAC Name:
1-[4-(3-methylphenyl)aminopyridin-3-yl]sulfonyl-3-propan-2-yl-urea

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