Valdecoxib

This page contains recent news articles, when available, and an overview of Valdecoxib but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Valdecoxib
(when available)

Pharmacology and use:
Valdecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Valdecoxib is used for its anti-inflammatory, analgesic, and antipyretic activities in the management of osteoarthritis (OA) and for the treatment of dysmenorrhea or acute pain. Unlike celecoxib, Valdecoxib lacks a sulfonamide chain and does not require CYP450 enzymes for metabolism. For the treatment of osteoarthritis and dysmenorrhoea

Mechanism Of Action:
Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane. Valdecoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, important for the mediation of inflammation and pain. Unlike non-selective NSAIDs, Valdecoxib does not inhibit platelet aggregation.

News Articles on Valdecoxib

Frankincense may bear the gift of healing  -  ‎Dec 21, 2009‎
In the third study, frankincense relieved pain from knee osteoarthritis as effectively as the prescription drug, valdecoxib. ... Irish Times

Pharmaceutical industry financial performance  -  ‎Dec 11, 2009‎
Safety-related revenue losses have also been rising in recent years (for example, for valdecoxib (Bextra; Pfizer), rosiglitazone (Avandia; GlaxoSmithKline), ... Nature.com (subscription)

The Pharmaceutical Industrial Complex: A Deadly Fairy Tale  -  ‎Oct 23, 2009‎
A separate FOI concerning a similar drug, Valdecoxib, had pages and paragraphs deleted because sections of the document were marked as “trade secrets. ... Auburn Journal

Stevens-johnson syndrome  -  ‎Oct 23, 2009‎
...vcitane roznych liekov(wikipedia uvadza napr(allopurinol, diclofenac, etravirine, fluconazole,[2] valdecoxib, sitagliptin, oseltamivir, penicillins, ... Zdravie.sk

Regulators call for valdecoxib withdrawal  -  Apr 7, 2005
Rockville, MD - International regulators have independently come to the same conclusion: valdecoxib (Bextra, Pfizer) should be pulled from the market. ... Medscape

Indian cos going slow on promoting Valdecoxib  -  Apr 13, 2005
IT is not off the shelf officially, but most Indian drug companies are not promoting their generic versions of arthritis drug Valdecoxib. ... Hindu Business Line

PFIZER INC.: FDA: Bextra side effects are 'potentially' life-...  -  Feb 9, 2006
..."In the absence of any demonstrated advantage over other [pain medications], the overall benefit versus risk profile for valdecoxib is unfavorable for ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

The fallout after valdecoxib  -  Apr 14, 2005
Rockville, MD - With the market removal of valdecoxib (Bextra, Pfizer) in many countries last week and new warnings cropping up for other selective and ... Medscape

Article: Valdecoxib banned, to hit 40 drug makers. - Economic Times (...  -  May 3, 2005
Valdecoxib banned, to hit 40 drug makers. ... find Economic Times (New Delhi, India) articles. May 3--NEW DELHI -- An expert committee under the health ... Pay-Per-View - Economic Times - HighBeam Research

Boswellia extract scores well in COX-2 comparison  -  Mar 20, 2007
The valdecoxib was Tab Valdon, from Cadila Pharamceuticals. ... The researchers found that in the valdecoxib group a statistically significant improvement ... NutraIngredients-usa.com

Valdecoxib (Systemic).  -  Oct 27, 2005
Not commercially available Valdecoxib was voluntarily withdrawn from the market in April 2005. Antirheumatic (nonsteroidal anti-inflammatory), ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Rofecoxib, valdecoxib associated with increased risk of stroke.  -  Sep 1, 2008
Rofecoxib, valdecoxib associated with increased risk of stroke. A retrospective cohort study published in the journal Stroke demonstrated an increased risk ... $9.94 - Formulary - Alacra Store

Painkillers a pain? Bextra exit raises new doubts  -  Apr 16, 2005
NEW DELHI, APRIL 15 With US regulatory authorities asking Pfizer, the patent holder of Valdecoxib, to voluntarily remove Bextra (its brand of the drug) from ... Indian Express

… clinical trial of Boswellia serrata extract as compared to valdecox...  -  Jan 1, 2007
In valdecoxib group the statistically significant improvement in all ... Three patients from BSE group and two from valdecoxib group complained of acidity. ... Free with registration - Indian Journal of Pharmacology - AccessMyLibrary.com

No Bextra.(News @ a glance)(COX-2 inhibitors)(Brief Article)  -  Feb 28, 2006
No Bextra: Following a review of safety information, Health Canada has decided that valdecoxib (Bextra), a COX-2 selective inhibitor used to treat arthritis ... Free with registration - CMAJ: Canadian Medical Association... - AccessMyLibrary.com

Pfizer suspends valdecoxib  -  Apr 9, 2005
GPs are set to face a fresh wave of patients alarmed over cox-2 inhibitors after the UK's drug regulator announced use of valdecoxib (Bextra) was being ... Pay-Per-View - Pulse - Factiva, from Dow Jones

Entire COX-2s class increases risk of MI  -  Apr 21, 2006
Current use of etoricoxib (Arcoxia) was associated with a two-fold increased risk of MI and valdecoxib (Bextra) with a more than four-fold increased risk. ... Pay-Per-View - GP - Factiva, from Dow Jones

Questions linger about proper use of COX-2 inhibitors: FDA panel sees...  -  Mar 15, 2005
On rofecoxib and valdecoxib, for which the evidence of cardiovascular risk was ... Several panelists recommended against using valdecoxib for more than 6 ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Acetaminophen Cross-Sensitivity Possible in Children Who React to …  -  Jun 13, 2006
One patient who took valdecoxib developed mild perioral angioedema. Patients who did not take COX-2 inhibitors used a variety of treatment measures, ... DG News

Kaiser Permanente issues moratorium on use of valdecoxib.( …  -  Mar 15, 2005
The health plan giant Kaiser Permanente has placed a 6-month moratorium on the dispensing of the cyclooxygenase-2 inhibitor valdecoxib (Bextra) from its ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Valdecoxib, Parecoxib Use Not Associated With Increased Stroke or...  -  Mar 8, 2005
March 8, 2005 (Orlando) — In a study of general surgery patients, use of valdecoxib (Bextra) and its prodrug parecoxib (Dynastat) for postsurgical pain ... Medscape

Three Pivotal Trials of COX-2 Inhibitors Released Early by NEJM  -  Feb 15, 2005
..."The use of parecoxib and valdecoxib after CABG was associated with an increased incidence ... Pharmacia and Pfizer, the makers of valdecoxib and parecoxib, ... Medscape

… of the COX-2 inhibitors parecoxib and valdecoxib after cardiac...  -  Apr 5, 2005
Of particular concern, patients treated with parecoxib and valdecoxib were 3.7 times more likely to experience a cardiovascular event than those given ... OnMedica

… restrictions on celecoxib (Celebrex) use and the withdrawal of...  -  Oct 11, 2005
Health Canada now recommends new restrictions on celecoxib use, and valdecoxib has been taken off the market. The US Food and Drug Administration has gone ... CMAJ

Company pulls pain drug from market.(Pfizer Inc.)(Brief Article)  -  Apr 23, 2005
...the Food and Drug Administration on April 7 asked Pfizer to remove its prescription pain medication valdecoxib (Bextra) from the market. ... $4.95 - Science News - ECNext

Cardiovascular Risks of Coxibs: The Orthopaedic Perspective  -  Jul 1, 2007
Valdecoxib (Bextra) itself has not been shown in prospective studies to have ... It would be reasonable to predict that valdecoxib has the same cardiac ... Journal of Bone and Joint Surgery - Journal of Bone and Joint Surgery...

India may ban Valdecoxib  -  Jun 23, 2005
The estimated Rs 90-crore Valdecoxib, indicated for arthritis and acute pain, may finally be on its way out in India. The National Pharmaco Vigilance ... expresspharmapulse.com

FDA panel sees role for COX-2s despite risks.(Clinical Rounds; Food...  -  Apr 1, 2005
Several panelists recommended against using valdecoxib for more than 6 months, ... Although the close votes for rofecoxib and valdecoxib are "challenging to ... Pay-Per-View - Skin & Allergy News - Factiva, from Dow Jones

… issues moratorium on use of valdecoxib.(Rheumatology) | Article...  -  Mar 15, 2005
Kaiser Permanente issues moratorium on use of valdecoxib.(Rheumatology) ... find Internal Medicine News articles. The health plan giant Kaiser Permanente ... Pay-Per-View - Internal Medicine News - HighBeam Research

Valdecoxib banned, to hit 40 drug makers.  -  May 3, 2005
Valdecoxib banned, to hit 40 drug makers. May 3--NEW DELHI -- An expert committee under the health ministry on Tuesday recommended that arthritis pill ... $9.94 - Knight Ridder/Tribune Business News - Alacra Store

EU Backs Bextra Withdrawal, Announces New Warnings for Cox-2s  -  Jun 28, 2005
...concluded that the additional risks of serious and potentially fatal skin reactions associated with the use of Bextra (valdecoxib) outweigh its benefits ... Pay-Per-View - Drug Industry Daily - Factiva, from Dow Jones

Are selective cyclo-oxygenase 2 inhibitors safe after coronary artery...  -  Jun 20, 2005
...(2005) Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac ... Specifically, patients treated with parecoxib and valdecoxib had ... Nature.com

… of FDA, the sales and marketing of valdecoxib (Bextra, Pfizer)...  -  May 1, 2005
At the request of FDA, the sales and marketing of valdecoxib (Bextra, Pfizer) were suspended indefinitely by the manufacturer. At the request of FDA, ... $9.94 - Formulary - Alacra Store

European Medicines Agency concludes action on COX-2 inhibitors  -  Jul 1, 2005
...the European Medicines Agency (EMEA) has recommended the suspension of the marketing authorisation for Bextra (valdecoxib) and recommended new ... Medical News Today - Medical News Today (press release)

Serious skin disorders and coxibs.  -  Sep 1, 2006
There were 123 cases in total, 63 for valdecoxib, 43 for celecoxib, and 17 for rofecoxib, ... For valdecoxib and celecoxib the median age was 62 years, ... $4.95 - Bandolier - ECNext

Questions linger about use of COX-2 inhibitors: an FDA advisory panel...  -  Mar 15, 2005
On rofecoxib and valdecoxib, for which the evidence of cardiovascular risk was ... Several panelists recommended against using valdecoxib for more than 6 ... Free with registration - OB GYN News - AccessMyLibrary.com

Pfizer's arthritis drug ban in West weighs down local clones.  -  Apr 9, 2005
The total valdecoxib market is valued at Rs 89.6 crore (February '05 MAT) here, ... Officials at Torrent and Unichem, two companies that market valdecoxib, ... Free with registration - Economic Times - AccessMyLibrary.com

Centre bans arthritis drug Bextra, finally  -  Aug 5, 2005
The reason could be that Valdecoxib was a newer drug, and it was doing much ... The total Valdecoxib market was valued at close to Rs 100 crore with the top ... Pay-Per-View - Economic Times - Factiva, from Dow Jones

FDA Advisory Panel Meeting to Focus on Drug-Safety Issues  -  Apr 14, 2005
...and the agency's decision to pull Pfizer's Bextra (valdecoxib) from the market and to require stringent "black-box" warnings on all Cox-2 inhibitors and ... Pay-Per-View - Drug Industry Daily - Factiva, from Dow Jones

Pharma firms face ban on Merck generic  -  Apr 16, 2007
Of the Cox II drugs, which include etoricoxib, celecoxib, valdecoxib and parecoxib, two drugs - rofecoxib (Merck's Vioxx) and valdecoxib (Pfizer's Bextra) ... Business Standard

FDA Safety Labeling Changes: Bextra, Phenergan, Cosmegen  -  Jan 26, 2005
24, the FDA approved revisions to the safety labeling for valdecoxib (Bextra ... Valdecoxib is contraindicated for the management of postoperative pain ... Medscape

Questions linger about use of COX-2 inhibitors: an FDA advisory panel...  -  Mar 15, 2005
On rofecoxib and valdecoxib, for which the evidence of cardiovascular risk was ... Several panelists recommended against using valdecoxib for more than 6 ... Pay-Per-View - OB GYN News - Factiva, from Dow Jones

Los antiinflamatorios advertirán de sus potenciales peligros  -  Apr 7, 2005
Valdecoxib (autorizado para tratar la artrosis, la artritis reumatoide y el dolor menstrual) todavía no estaba disponible en España, ... elmundo.es

Vioxx, Bextra linked to increased stroke risk: study  -  Aug 7, 2008
..."This study suggests that rofecoxib and valdecoxib were associated with higher stoke risk than other NSAIDs," Roumie said in the interview. ... Reuters India

Expanded information on Cox-2 inhibitors for doctors and pharmacists,...  -  Feb 12, 2005
Valdecoxib has not been marketed in Australia. Valdecoxib has been associated with an increased risk of cardiovascular events in cardiac by-pass graft ... Medical News Today - Medical News Today (press release)

Are Selective Cyclo-oxygenase 2 Inhibitors Safe After Bypass?:...  -  Oct 3, 2005
Specifically, patients treated with parecoxib and valdecoxib had significantly more cardiovascular events than patients treated with placebo (11 [2.0%] ... Medscape

mg | Definition of mg | HighBeam.com: Online Dictionary  -  Jul 12, 2006
Article: UV spectrophotometric simultaneous estimation of valdecoxib and ... ... Standards of paracetamol (250 mg) and valdecoxib (10 mg) were weighed ... Pay-Per-View - Oxford American College Dictionary - HighBeam Research

'New England' cuestiona la utilidad de todos los COX-2  -  Feb 15, 2005
Bextra: Tras investigar a más de 1.600 pacientes recién operados que recibieron valdecoxib y parecoxib (su versión inyectable), valdecoxib y un placebo o ... elmundo.es

FDA advisory committees recommend marketing of COX-2 inhibitors with...  -  Mar 1, 2005
The limited cardiovascular safety database of valdecoxib was cited as a reason for a ... For celecoxib and valdecoxib, most of the committee members favored ... Free with registration - Formulary - AccessMyLibrary.com

Arthritis Medicines and Cardiovascular Events—"House of Coxibs"  -  Jan 19, 2005
On December 9, 2004, the US Food and Drug Administration (FDA) issued a black box warning for valdecoxib for life-threatening skin reactions and ... Journal of American Medical Association - Journal of American Medical Association...

Celecoxib beneficiary of coxib withdrawals  -  May 25, 2005
The US Food and Drug Administration recommended that valdecoxib be withdrawn ... In a new statement about valdecoxib, Pfizer said, "We will explore options ... Medscape

Formulary decision-makers update P&T policies following COX-2...  -  Jul 1, 2005
Prior to the withdrawal of rofecoxib and valdecoxib, Independent Health of Buffalo, NY, covered celecoxib and rofecoxib in their preferred tier (tier 2) but ... $9.94 - Formulary - Alacra Store

Assessing the risk of anaphylaxis with COX-2 inhibitors: what is the...  -  Apr 1, 2005
Warning labels on celecoxib and valdecoxib also list sulfonamide allergy as a ... Valdecoxib has not been described in the published literature to cause ... $4.95 - Journal of Respiratory Diseases - ECNext

Press Release: Attorney General Gansler Settles With Pfizer, Inc.; …  -  Oct 23, 2008
Another drug in this class, Bextra (valdecoxib) has shown an increased risk for CV events in patients after heart surgery. Bextra and Celebrex are the only ... Pay-Per-View - M2 Presswire - HighBeam Research

FDA驳回辉瑞å?¬å›žè?¯ç‰©Bextra的新é…?æ–¹  -  Sep 21, 2005
...去年春天,FDAè¦?求辉瑞将Bextra -- 其通用å??为Valdecoxib -- 撤出市场,ç?†ç”±æ˜¯è¿™ç§? è?¯ç‰©ä¸Žä¸€ç§?罕è§?但æŸ?些情况下会致命的皮肤å??应:å?²è’‚文斯-约翰逊 ... 新浪网

The Role of Litigation in Defining Drug Risks  -  Jan 17, 2007
For example, the selective cyclooxygenase inhibitor valdecoxib was submitted for approval in ... 4 Valdecoxib was withdrawn from the market a year later. ... Journal of American Medical Association - Journal of American Medical Association...

Article: FDA pulls arthritis painkiller due to health risks. -...  -  Apr 8, 2005
Gynecology showed that the COX-2 specific inhibitor Bextra (valdecoxib tablets ... In addition to calling for valdecoxib (Bextra) to be voluntarily removed ... Pay-Per-View - Monitor - HighBeam Research

Cardiology show highlights antiplatelet agent, COX-2 risks.(CLINICAL ...  -  Apr 18, 2005
The session "Safety of Parecoxib and Valdecoxib in the Treatment of ... Whelton concluded that while parecoxib and valdecoxib should not be used during ... Free with registration - Drug Topics - AccessMyLibrary.com

Ranbaxy discontinues arthritis drug  -  Apr 12, 2005
Ranbaxy Laboratories Ltd [ Get Quote ] on Tuesday said it has decided to discontinue all its 'Valdecoxib' formulations with immediate effect from Indian ... Rediff

Effects of a non-selective COX inhibitor and selective COX-2 inhibitor...  -  May 26, 2008
Diclofenac and valdecoxib significantly decreased the amplitude of ... Valdecoxib was more potent in proximal specimens of human ureter (EC 50 =7.3 10 -11 ... Nature.com

Some Pain Medicines May Inhibit Healing.  -  Mar 22, 2006
..."Rats treated immediately following surgical repair with COX-2 inhibitors, including Celecoxib (Celebrex) and Valdecoxib (Bextra), had weaker tendons and a ... Free with registration - PR Newswire - AccessMyLibrary.com

Schorsing van het COX-2-selectief NSAID valdecoxib (Bextra®)  -  Apr 11, 2005
Het European Medicines Agency (EMEA) heeft beslist het COX-2-selectief NSAID valdecoxib (Bextra®) te schorsen in de landen van de Europese Unie. ... Belgisch centrum voor farmacotherapeutis...

Bextra withdrawn from market.(News) | Article from Skin & Allergy...  -  May 1, 2005
News) ... find Skin & Allergy News articles. The market withdrawal of valdecoxib and the black box warnings on celecoxib and all other remaining prescript. Pay-Per-View - Skin & Allergy News - HighBeam Research

COX-2 Inhibitors, Other NSAIDs, and Cardiovascular Risk  -  Sep 12, 2006
No such effects were present with celecoxib, valdecoxib, or etoricoxib. Moreover, in a time-cumulative analysis, the authors suggest that the risk of ... Journal of American Medical Association - Journal of American Medical Association...

Cardiovascular Outcomes  -  Mar 14, 2005
In a 10-day randomized trial of pain relief after coronary artery surgery, 1671 patients received either intravenous parecoxib (a prodrug of valdecoxib) ... Medscape

Naproxen first line therapy over coxibs  -  Feb 19, 2005
Committee members questioned whether valdecoxib (Bextra, Pfizer) should have ever been approved at all considering the "paucity of data" and the additional ... Medscape

Utili in calo per Pfizer  -  Oct 20, 2005
...ad aprile, dell'antidolorifico Bextra (valdecoxib) ritenuto responsabile di gravi effetti collaterali a livello del sistema cardiovascolare. Pharma Marketing

Farmaci: Pfizer ritira da commercio antinfiammatorio Bextra  -  Apr 11, 2005
...(ANSA) - ROMA, 11 APR - La casa farmaceutica Pfizer ha deciso di ritirare dal commercio il farmaco antinfiammatorio a base di valdecoxib Bextra. ... Regione Basilicata

FDA rejects parecoxib, only injectable COX-2 inhibitor  -  Sep 20, 2005
But Pfizer counters that the new prodrug to valdecoxib has been shown to reduce the need for opioids to control pain following surgery. ... Medscape

FDA recommends limiting COX-2 inhibitors use: an advisory committee …  -  Feb 1, 2005
Physicians prescribing celecoxib or valdecoxib should consider this emerging information when weighing the benefits against risks for individual patients. ... Free with registration - Drug Formulary Review - AccessMyLibrary.com

Some Popular Non-aspirin Pain Drugs May Slow Tendon Healing  -  Mar 27, 2006
After surgery, the rats were divided into six treatment groups receiving celecoxib, naproxen, piroxicam, acetaminophen, ibuprofen or valdecoxib in their rat ... emaxhealth.com

Press Release: Weitz & Luxenberg Responds to Bextra Recall. - PR …  -  Apr 7, 2005
Article: Pfizer Statement on Bextra(R) (Valdecoxib). PR Newswire; November 10, ... Article: BEXTRA(R) (valdecoxib tablets) Approved by FDA for ... ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Pfizer pulls pain drug Bextra. - Pittsburgh Post-Gazette...  -  Apr 8, 2005
Article: BEXTRA(R) (valdecoxib tablets) Approved by FDA for ... PR Newswire; November 19, 2001 ; 700+ words ... ... Drug Administration (FDA) has approved ... Pay-Per-View - Pittsburgh Post-Gazette - HighBeam Research

Reporting of clinical trials of analgesia  -  Feb 1, 2006
Ott and colleagues 1 commendably sought to provide a risk-benefit assessment of the use of parecoxib and valdecoxib in the post–coronary artery bypass ... The Journal of Thoracic and Cardiovascul...

Vioxx's Indian make still on sale  -  Aug 25, 2005
NEW DELHI: Arthritis drugs Rofecoxib and Valdecoxib, both of which are globally ... Valdecoxib, meanwhile, was withdrawn from India, just three weeks back, ... Times of India

The Hindu Business Line  -  Apr 18, 2005
After the global recall of Rofecoxib, there was a question mark over the entire family of drugs, including Celecoxib, Valdecoxib and Etorecoxib. ... Hindu Business Line

Centre set to take fresh look at Rofecoxib ban.  -  Feb 22, 2005
Restrictive labelling on Celecoxib and Valdecoxib is already in place here." ... It also voted in favour of allowing Valdecoxib and Celecoxib of the same ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

FDA reprimands Pfizer for Celebrex and Bextra ads  -  Jan 14, 2005
Rockville, MD - The US FDA has reprimanded Pfizer over 5 promotional pieces that feature celecoxib (Celebrex) and valdecoxib (Bextra), because they contain ... Medscape

Coxibs curtailed in Australia  -  Feb 11, 2005
For valdecoxib (Bextra, Pfizer), which is converted to parecoxib in the body, ... The decisions on parecoxib and valdecoxib were made on the basis of 2 ... Medscape

Largest study to date supports NSAID class effect on MI risk.(Nonstero...  -  Jul 15, 2005
But both celecoxib (Celebrex) and valdecoxib (Bextra) do not seem to increase the risk ... Some of the most selective drugs, like celecoxib and valdecoxib, ... Free with registration - Family Practice News - AccessMyLibrary.com

Newer cox-II inhibitors to face stringent scrutiny  -  May 12, 2005
Following the recent US FDA decision on valdecoxib and withdrawal of ... However, with rofecoxib already out of market and valdecoxib falling in line, ... expresspharmapulse.com

Las revistas ganan una batalla judicial para preservar su independenci...  -  Mar 25, 2008
..."En respuesta, les remitimos cientos de páginas de artículos publicados sobre celecoxib y valdecoxib", explica el editorial de JAMA, "sin embargo, ... elmundo.es

Oral analgesics for acute nonspecific pain.  -  Mar 1, 2005
Valdecoxib (20 mg and 40 rag) has been effective for acute postoperative pain of ... (27) Valdecoxib also has demonstrated analgesia superior to that of ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Oral analgesics for acute nonspecific pain.  -  Mar 1, 2005
Valdecoxib (20 mg and 40 rag) has been effective for acute postoperative pain of ... (27) Valdecoxib also has demonstrated analgesia superior to that of ... $4.95 - American Family Physician - ECNext

Updates on the management of upper gastrointestinal disorders in the ...  -  Mar 1, 2007
The effect of valdecoxib, the third COX-2 inhibitor approved for use in the United ... Complications of the COX-2 inhibitors parecoxib and valdecoxib after ... $4.95 - Journal of Family Practice - ECNext

… advice on what you can do.(HEART BEAT)(Rofecoxib and valdecoxib )(  -  Nov 1, 2006
HEART BEAT)(Rofecoxib and valdecoxib )(Brief article) ... find Heart Advisor articles. Rofecoxib and valdecoxib are no longer on pharmacy shelves, ... Pay-Per-View - Heart Advisor - HighBeam Research

Arthritis Therapy; Regulator takes action on Cox-2 Inhibitors...  -  Mar 20, 2005
Valdecoxib has not been marketed in Australia. Valdecoxib has been associated with an increased risk of cardiovascular events in cardiac by-pass graft ... Pay-Per-View - Heart Disease Weekly - Factiva, from Dow Jones

Physicians, patients decry COX-2 withdrawals: Bextra voluntarily …  -  May 1, 2005
Clinical Rounds) ... find OB GYN News articles. The market withdrawal of valdecoxib and the black box warnings on celecoxib and all other remaining prescript... Pay-Per-View - OB GYN News - HighBeam Research

COX-2 withdrawals complicate pain relief decisions: few options left...  -  May 1, 2005
The market withdrawal of valdecoxib and the black box warnings on celecoxib and all other remaining prescript... Pay-Per-View - Family Practice News - HighBeam Research

Common OTC Drug Could Pose Serious Risk For Some  -  Sep 16, 2008
Not long after, valdecoxib, marketed as Bextra, was removed for the same reason. Since then, anxieties surrounding the cardiovascular safety of nonselective ... emaxhealth.com

Press Release: Some Pain Medicines May Inhibit Healing. - PR Newswire...  -  Mar 22, 2006
..."Rats treated immediately following surgical repair with COX-2 inhibitors, including Celecoxib (Celebrex) and Valdecoxib (Bextra), had weaker tendons and a ... Pay-Per-View - PR Newswire - HighBeam Research

Are Coxibs better than NSAIDs for the Treatment of Chronic Pain?  -  Nov 5, 2007
Furthermore, two of the coxibs, celecoxib and valdecoxib, produced more favourable outcomes for both gastrointestinal and cardiovascular outcomes. ... Virtual Medical Centre - The Virtual Medical Centre

Public Citizen files coxib petition  -  Jan 27, 2005
..."The FDA should immediately ban the sale of celecoxib and valdecoxib, which put millions of people, many of them elderly, at risk of heart attack," Dr ... Medscape

Cough syrup controversy still haunts N Piramal.  -  Jan 27, 2006
Besides Phensedyl sales, withdrawal of two highly profitable Valdecoxib brands ... NPIL's another brand Valdecoxib was discontinued by the company in July ... Free with registration - Economic Times - AccessMyLibrary.com

Animal study on vascular effects of COX-2 inhibition  -  Jan 17, 2005
A related editorial, Furberg et al, titled, "Parecoxib, Valdecoxib and Cardiovascular Risk," presents a meta-analysis of two clinical studies, and examines ... News-Medical.net

FDA Panel: Keep COX-2 Drugs on Market Black Box for COX-2 Labels, …  -  Apr 6, 2005
Valdecoxib also squeaked by with a vote of 17-13, with two panel members abstaining. "The committee was more comfortable with the risk profile of celecoxib, ... Journal of American Medical Association - Journal of American Medical Association...

Further doubt cast over safety of Bextra.(Brief Article)  -  Jan 3, 2005
..."We believe the doubts raised about the safety of valdecoxib constitute an imminent hazard to public health and thus require action," the researchers ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

FDA MEETING REPORT: COX-2 Inhibitors Can Be Marketed, But With …  -  Feb 20, 2005
Consider following the panel's recommendations to use Bextra (valdecoxib) and Vioxx (rofecoxib) only as second-line medications and at the lowest possible ... MedPage Today

More Evidence of COX-2 Inhibitor Risks - Vioxx (rofecoxib) Colorectal...  -  Feb 15, 2005
With still more COX-2 inhibitor news likely as the FDA hearings begin, patients may ask about the safety of Celebrex®(celecoxib) and Bextra®(valdecoxib). ... MedPage Today

La Agencia Europea del Medicamento revisa los COX-2  -  Jan 19, 2005
..."Es prudente evitar el consumo de valdecoxib o utilizarlo sólo como último ... "Dada la experiencia clínica con rofecoxib y valdecoxib, el impacto de ... elmundo.es

Ross v. Astrue, No. 4:06-CV-1525 (EDMo. 03/24/2008)  -  Mar 24, 2008
Valdecoxib is in a class of nonsteroidal anti-inflammatory medications called ... Valdecoxib has been taken off the market after research indicated that it ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

NSAIDs' class effect on MI risk affirmed in largest 'by far' study.(Cl...  -  Sep 1, 2005
But both celecoxib (Celebrex) and valdecoxib (Bextra) do not seem to increase the risk ... Some of the most selective drugs, like celecoxib and valdecoxib, ... Pay-Per-View - Skin & Allergy News - Factiva, from Dow Jones

Safety concerns over COX-2s deepen.(COX-2 inhibitors)(Brief Article)  -  Jan 24, 2005
In addition, a related editorial by Furberg et al, called Parecoxib, valdecoxib and cardiovascular risk, investigated the association between the ... $4.95 - Pharma Marketletter - ECNext

Article: FDA now reviewing panel's nod to COX-2s: celecoxib garnered ...  -  Apr 1, 2005
FDA now reviewing panel's nod to COX-2s: celecoxib garnered nearly unanimous support; vote was more divided on rofecoxib and valdecoxib. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Brand Names/Synonyms:
Valdecoxib is also known by the following brand names and/or synonymsBextra; Valdecoxib; Valdecoxib [Usan]

Drug Category:
Valdecoxib is categorized under the following by the FDA: Anti-inflammatory Agents; Nonsteroidal Antiinflammatory Agents (NSAIDs); ATC:M01AH03

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
[an error occurred while processing this directive]



Chemical IUPAC Name:
4-(5-methyl-3-phenyl-oxazol-4-yl)benzenesulfonamide





Health Home | Conditions | Cancer | Medications | Surgery | Vaccines


The Cancer News Network


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on cancernewsnetwork.org lead to other sites. cancernewsnetwork.org does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is CancerNewsNetwork.org responsible for dead or misdirected links.

IF YOU NEED A LINK OR TEXT REMOVED FROM THIS PAGE PLEASE CONTACT cancernewsnetwork (at) live.com.
We will do our best to accommodate your request.



COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy