Valproate

This page contains recent news articles, when available, and an overview of Valproate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

FDA Studies Safe Drugs During Pregnancy  -  ‎Jan 4, 2010‎
Pregnant women taking the drug valproate to treat epilepsy, may significantly increase their baby's risk of developing autism, according to a new study ... InjuryBoard.com (blog)

Lithium Beats Valproate for Long-Term Bipolar Therapy  -  ‎Dec 23, 2009‎
23 (HealthDay News) -- People with bipolar I disorder will do best over the long term with lithium treatment alone or a combination of lithium and valproate ... BusinessWeek

Valproate Work Better With Lithium Than Alone  -  ‎Dec 27, 2009‎
BALANCE, which stands for Bipolar Affective disorder: Lithium/ANticonvulsant Evaluation, is a multi-country study to compare the effectiveness of valproate ... About - News & Issues (blog)

EU Panel Backs DuoCover From Bristol-Myers Squibb Pharma  -  ‎Dec 18, 2009‎
...-The Committee completed a review of the safety and efficacy of valproate in the treatment of manic episodes in bipolar disorder, concluding that the ... Wall Street Journal

Valproate Sodium and related products (valproic acid and divalproex sodium)  -  ‎Dec 24, 2009‎
Healthcare practitioners should inform women of childbearing potential about these risks, and consider alternative therapies, especially if using valproate ... Ethiopian Review

Combined Lithium Plus Valproate Or Lithium Monotherapy Better At Preventing ...  -  ‎Dec 26, 2009‎
For people with bipolar I disorder*, for whom long-term therapy is clinically indicated, both combination therapy with lithium plus valproate and lithium ... Medical News Today (press release)

FDA, Manufacturers Advise Physicians of Actions Involving Various Drugs  -  ‎Dec 11, 2009‎
The agency approved valproic acid for the treatment of epilepsy more than 30 years ago, but it more recently approved valproate for the treatment of bipolar ... AAFP News Now

Pharmacotherapy for borderline personality disorder: Cochrane systematic ...  -  ‎Dec 31, 2009‎
Most beneficial effects were found for the mood stabilisers topiramate, lamotrigine and valproate semisodium, and the second-generation antipsychotics ... British Journal of Psychiatry

Brain Finding Raises Concerns About Seizure Drug in Children  -  ‎Dec 18, 2009‎
A study published in the April 16 New England Journal of Medicine warned of long-term detrimental effects of valproate, another antiepileptic drug, ... Psychiatric News

Brain serotonin-2 receptors in acute mania  -  ‎Dec 31, 2009‎
The fact that YMRS scores did not correlate with 5-HT 2 binding and that treatment of acute mania with valproate does not alter brain 5-HT 2 receptors 29 ... British Journal of Psychiatry

Trouble bipolaire: le lithium serait un traitement plus efficace que le valproate  -  ‎Dec 28, 2009‎
Une combinaison de lithium (Téralithe) et de valproate (Depakene, Épival, Acide valproïque) (1) ou le lithium seul sont plus efficaces que le valproate seul ... PsychoMédia

Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice ...  -  ‎Nov 13, 2009‎
Activity in the TST tended to be attenuated by acute treatment with valproate at 300 mg/kg in KO mice. The PKCI/HINT1 KO mice presented less thigmotaxis in ... 7thSpace Interactive (press release)

Akhileshwar Sahay | Life lessons from one man's fight with bipolar disorder  -  ‎Nov 4, 2009‎
His fingers, as they light one of the many cigarettes he smokes each day, quiver with a barely perceptible tremor—a possible side effect of sodium valproate ... Livemint

More Than Genes III: The Fetus, Toxic Chemicals, and Autism  -  ‎Nov 9, 2009‎
...metabolic, and neurologic disorders have been associated with autism, including fragile X syndrome, Down syndrome, fetal valproate embryopathy, ... Psychology Today (blog)

Reduced levels of reactive oxygen species correlate with inhibition of ...  -  ‎Nov 10, 2009‎
...while the thioredoxin antioxidant protein is highly expressed in BLV-infected B lymphocytes, (ii) induction of ROS by valproate (VPA) is pro-apoptotic, ... 7thSpace Interactive (press release)

DNA repair could lessen autism  -  ‎Nov 11, 2009‎
Interested individuals should be aged under 15 years and not currently taking folate or sodium valproate (Epilim). Editor's Note: Original news release can ... ScienceAlert

Autism: moving beyond the quest for a cure  -  ‎Nov 5, 2009‎
But not a single new environmental contributor to autism has been identified since the anti-epileptic drug Sodium Valproate more than 20 years ago. ... Spiked

Neighborhoods of Dual-Diagnosis Patients  -  ‎Nov 2, 2009‎
Carbamazepine and valproate are considered compatible with breastfeeding, but nighttime breastfeeding may lead to sleep deprivation, a possible trigger for ... Am J Psychiatry (subscription)

Practical Approach: Identifying and treating female hirsutism  -  ‎Nov 3, 2009‎
Some combined and progestogen-only oral contraceptives, anabolic steroids and sodium valproate. 3. Acne and/or a male balding pattern may indicate raised ... Chemist+Druggist

Bipolar II Postpartum Depression: Detection, Diagnosis, and Treatment  -  ‎Nov 2, 2009‎
In general, carbamazepine and valproate are considered compatible with breastfeeding. Lamotrigine should be used cautiously because of concerns about skin ... Am J Psychiatry (subscription)

What's the evidence for valproate?  -  Dec 4, 2008
There is reasonably good evidence that taking valproate helps to stop or reduce seizures for many people. The studies we found compared valproate with other ... guardian.co.uk

Epilepsy Drug May Raise Autism Risk in Offspring  -  Dec 2, 2008
2 issue of Neurology, add to previous research showing that valproate and other ... That's an indication that valproate affects brain development," said Dr. ... Forbes

THE NATION; Study Ties Epilepsy Drug to Fetal Risk  -  Aug 8, 2006
One in five women who took the widely used epilepsy drug valproate in a ... Twenty percent, or 14, of the 69 women on valproate had pregnancies that ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Effect of Sodium Valproate on Nocturnal Melatonin Sensitivity to...  -  Apr 20, 2005
Correspondence: Professor TR Norman, Department of Psychiatry, The University of Melbourne, Austin Hospital, Level 10 Lance Townsend Building, ... Nature.com

Epilepsy Drug Valproate Used During Pregnancy Linked To Lower IQ in …  -  May 9, 2007
ScienceDaily (May 9, 2007) — Children of women who took the epilepsy drug valproate during pregnancy appear to be at a greater risk for lower IQ, ... sciencedaily.com

Self-repair gene therapy promise  -  May 7, 2006
Valproate was also found to raise SMN levels in brain tissue. The team first treated 10 parents of children with SMA with valproate for four months. ... BBC News

Epilepsy drug 'can increase the risk of children developing autism'  -  Dec 1, 2008
Scientists found that women who took valproate while pregnant were ... In total 64 of the children had been exposed to valproate while in the womb. ... Telegraph.co.uk

Action over epilepsy drug 'could rival thalidomide'  -  May 22, 2006
The court action applies specifically to the drug sodium valproate, which is only one of several ... Sodium valproate has been used since the 1970s. ... Telegraph.co.uk

Topamax May Raise Risk of Birth Defects  -  Jul 21, 2008
The birth defect rate was highest among women who took Topamax in combination with the epilepsy drug valproate, which has been linked to birth defects in ... CBS News

Efficacy of valproate maintenance in patients with bipolar disorder...  -  Jan 6, 2005
Treatment with valproate significantly reduces the number of heavy drinking days for patients with bipolar disorder and alcoholism, according to this report ... OnMedica

J&J Division Gets Not Approvable Letter  -  May 20, 2005
The product is approved for use as therapy alone or in combination with drugs called mood stabilizers, such as lithium or valproate. ... TheStreet.com - TheStreet.com (subscription)

General Practitioners and Women Still Not Getting Valproate Message  -  May 11, 2007
May 11, 2007 — In utero exposure to the anticonvulsant drug valproate increases the risk for poor cognitive outcomes and anatomical malformations compared ... Medscape

Valproate Taken During Pregnancy May Increase Risk of Fetal …  -  Mar 21, 2005
March 21, 2005 — Valproate taken during pregnancy is associated with increased risks of fetal malformations and abnormal neuropsychological development, ... Medscape

Epilepsy Drug, Pregnancy Up Autism Risk  -  Dec 1, 2008
1, 2008 -- Women who take the epilepsy drug valproate while pregnant may increase ... Sixty-four of the children were exposed to valproate during pregnancy, ... WebMD

Valproic acid, valproate and divalproex in the maintenance treatment...  -  Jul 1, 2007
Although lithium has been the most commonly used maintenance treatment in bipolar disorder for several decades, valproate is being used increasingly ... Medscape

Viewpoint: Get the Best Valproate Level for Acute Mania  -  Mar 30, 2006
According to American Psychiatric Association (APA) guidelines, valproate has a broad therapeutic range, from 50 to 125 mcg/mL, when used in the treatment ... Medscape

Avoid valproate as first-line Tx in fertile women.(Neurology)  -  Jan 15, 2005
NEW ORLEANS -- Valproate should not be prescribed as first-line therapy for any indication in women of childbearing age because it increases the risk of ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Lamotrigine, Valproate Effective as First-Line Treatments of Various.....  -  Mar 27, 2007
March 27, 2007 — New research suggests lamotrigine should replace carbamazepine as first-line therapy for patients with partial epilepsy, and valproate ... Medscape

Study Links Epilepsy Drug To Birth Defects .  -  May 4, 2007
...was the latest to document the potential dangers of valproate to unborn children Last summer, researchers reported in 5 women who took the drug, ... St. Petersburg Times - Google News Archive

Valproate linked to poor fetal outcomes.(Women's Health)  -  Dec 15, 2006
Valproate poses by far the greatest teratogenic risk of all the commonly prescribed antiepileptic drugs, according to Dr. Kimford J. Meador of the ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Noven Announces Final FDA Approval of Stavzor(TM) for the Treatment...  -  Jul 30, 2008
..."Valproate, the active ingredient in Stavzor, is recommended by the American ... "Our research indicates that valproate patients would prefer a small, ... Genetic Engineering News - Genetic Engineering News (press release)

Anticonvulsant Divalproex Valproate Sodium Valproic Acid Antimanic …  -  Jul 28, 2005
Valproic acid, valproate sodium, and divalproex belong to the group of medicines called anticonvulsants. They are used to control certain types of seizures ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Mum's epilepsy med linked to low IQ in kids  -  May 15, 2007
The children of women who used the epilepsy drug valproate while pregnant are ... "Children exposed to valproate [in utero] seem to display an IQ reduction ... National Review of Medicine

In Utero Exposure To Valproate Linked to Poor Cognitive Outcomes in …  -  Dec 8, 2006
December 8, 2006 (San Diego) -- In utero exposure to the antiepileptic drug (AED) valproate poses a much greater risk for poor behavioral developmental ... Medscape

Foetal Exposure to Valproate Affects Cognitive Development in...  -  Dec 10, 2008
By Adi Ferrara. SEATTLE, Wash -- December 10, 2008 -- Children exposed to valproate in utero have a significantly lower intelligence quotient (IQ) compared ... DG News

Discontinuing valproate may reverse PCOS in some women.(Gynecology …  -  Mar 1, 2005
BRECKENRIDGE, COLO. -- Hormonal evidence of polycystic ovary syndrome in patients on valproate is often reversed by a switch to one of the newer ... Pay-Per-View - OB GYN News - Factiva, from Dow Jones

Article: In utero valproate exposure tied to cognitive impairment.( …  -  Feb 15, 2007
In utero valproate exposure tied to cognitive impairment.(Neurology) ... find Internal Medicine News articles. SAN DIEGO -- In utero exposure to valproate ... Pay-Per-View - Internal Medicine News - HighBeam Research

Lamotrigine + valproate linked to birth defects.(Women's Health)  -  May 15, 2006
WASHINGTON -- There is no evidence that lamotrigine monotherapy increases the risk of major congenital malformations in infants exposed prenatally to the ... Free with registration - Internal Medicine News - AccessMyLibrary.com

… valproic acid (generic) (brand) valproate (common name).(YOUR …  -  Jun 1, 2005
IMPORTANT SIDE EFFECTS: Valproate should not be used in children under 2 years ... Rarely, valproate may have to be discontinued due to excessive hair loss. ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

Weight gain on valproate often normal growth.(Clinical Rounds)  -  Apr 1, 2006
LOS ANGELES -- Children taking sodium valproate for epilepsy may not be as vulnerable as adults to significant weight gain associated with the medication, ... Free with registration - Pediatric News - AccessMyLibrary.com

… Approves Aripiprazole as Adjunctive to Lithium or Valproate in...  -  May 9, 2008
TOKYO and PRINCETON, NJ -- May 9, 2008 -- The US Food and Drug Administration (FDA) has approved aripiprazole (Abilify) as an adjunctive therapy to either ... DG News

Drug Choices for Different Seizures Get Clarification  -  Mar 23, 2007
The other part of SANAD recruited 716 patients and compared valproate (Depacon) ... Valproate, they concluded, is better tolerated than topiramate and more ... MedPage Today

Side Effects from Epilepsy Drug - WebMD  -  Mar 21, 2005
In two new studies, children born to mothers who took valproate during early pregnancy had higher rates of birth defects and lowered verbal IQ. ... WebMD

Valproate effective in adult spinal muscular atrophy (SMA)  -  Jun 24, 2006
By Washington University School of Medicine, An epilepsy drug that has been on the market for decades can ease the symptoms of adult sufferers with a ... RxPG NEWS

… and Cholesterol Gains Greater with Valproate than with Lamotrigine...  -  Dec 8, 2005
By Fran Lowry. WASHINGTON, DC -- December 8, 2005 -- Young epileptic women treated with valproate (VPA) gain more weight and have worse cholesterol levels ... DG News

Epilepsy Drug Linked to Low IQ  -  May 3, 2007
In addition, 24% of toddlers born to mothers who took valproate had IQ scores ... "That said, valproate remains an important treatment option in women who ... WebMD

"Smart" Genetic Therapy Helps The Body To Heal Itself  -  May 11, 2006
Professor Wirth's team identified a drug - valproate, used successfully in epilepsy ... Later, they showed that valproate also raised SMN levels in neuronal ... Medical News Today - Medical News Today (press release)

In utero sodium valproate exposure linked to higher risk of autism.(Ne...  -  Dec 15, 2008
In utero sodium valproate exposure linked to higher risk of autism.(News) ... find OB GYN News articles. Exposure to sodium valproate early in pregnancy may ... Pay-Per-View - OB GYN News - HighBeam Research

Valproate may help child with bipolar disorder.(Behavioral Pediatrics)...  -  May 1, 2005
ATLANTA -- Valproate appears to have a beneficial effect on the manic symptoms of child and adolescent patients with bipolar disorder, but no large scale ... Free with registration - Pediatric News - AccessMyLibrary.com

Article: Valproate, birth defects update.(Clinical Rounds) - Family...  -  Jul 1, 2007
Valproate, birth defects update.(Clinical Rounds) ... find Family Practice News articles. BOSTON -- Two new data sets reinforce the recommendation to avoid ... Pay-Per-View - Family Practice News - HighBeam Research

Valproate riskier than other AEDs to fetus: risk of major malformation...  -  Sep 1, 2006
Valproate riskier than other AEDs to fetus: risk of major malformation or fetal death with valproate is 20%, vs. 8% with carbamazepine. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

… ABILIFY(R) (aripiprazole) for Add-On Treatment to Lithium or Valpro...  -  May 8, 2008
The approval of ABILIFY used in combination with lithium or valproate is based on results from a six-week, randomized, double-blind, placebo-controlled ... Genetic Engineering News - Genetic Engineering News (press release)

NICE recommendations for valproate treatment are unhelpful  -  May 5, 2005
East London and City Mental HealthTrust, Department of Adult Psychiatry, Royal London Hospital, Whitechapel, London E1 1BB, UK. ... British Journal of Psychiatry (subscript...

Sodium valproate exposure in utero linked to autism risk.(Mental...  -  Dec 15, 2008
Sodium valproate exposure in utero linked to autism risk.(Mental Health) ... find Family Practice News articles. Exposure to sodium valproate early in ... Pay-Per-View - Family Practice News - HighBeam Research

Lamotrigine, valproate emerge as superior epilepsy treatment options...  -  Aug 1, 2007
The results of the Standard and New Antiepileptic Drugs (SANAD) trial, an unblinded, randomized, controlled, 2-arm study comparing the efficacy of various ... $4.95 - Formulary - ECNext

Trial finds valproate performs no better than placebo for Alzheimer's...  -  Jul 1, 2006
According to Pierre Tariot, MD, director of the Memory Disorders Center at the Banner Alzheimer's Institute in Phoenix, agitation is one of the most ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Valproate use related to PCOS in 10% of bipolar women.(News)( …  -  Jan 1, 2005
PHOENIX, ARIZ. -- Valproate used as a mood stabilizer in bipolar disorder can cause polycystic ovary syndrome in about 10% of the women who take it, ... Pay-Per-View - Clinical Psychiatry News - Factiva, from Dow Jones

Valproate riskier than other AEDs to fetus: risk of major malformation...  -  Sep 1, 2006
Valproate poses by far the greatest teratogenic risk of all the commonly prescribed antiepileptic drugs, according to Dr. Kimford J. Meador of the ... Pay-Per-View - Clinical Psychiatry News - Factiva, from Dow Jones

In utero valproate exposure tied to cognitive impairment.(Neurology)  -  Feb 15, 2007
SAN DIEGO -- In utero exposure to valproate is associated with a greater risk of cognitive impairment in offspring, compared with exposure to other commonly ... $4.95 - Internal Medicine News - ECNext

Folic acid supplementation for women with epilepsy who might become …  -  Oct 23, 2008
2 Moreover, considering the capacity of valproate to also treat comorbid conditions ... (2007) The SANAD study of effectiveness of valproate, lamotrigine, ... Nature.com

Valproate-induced chorea and encephalopathy in atypical nonketotic …  -  Feb 1, 2007
Case: An 11-year-old female with a diagnosis of mild mental retardation, tremor and autistic spectrum disorder and otherwise a history of good health ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

Discontinuing valproate may reverse PCOS in some women.(Gynecology …  -  Mar 1, 2005
Discontinuing valproate may reverse PCOS in some women.(Gynecology) ... find OB GYN News articles. BRECKENRIDGE, COLO. -- Hormonal evidence of polycystic ... Pay-Per-View - OB GYN News - HighBeam Research

Valpro - Sodium valproate - Medical Drug  -  Mar 5, 2006
Valpro is a medicine used in the treatment of several different types of epilepsy, and in mania. Valpro works to treat epilepsy by preventing the excessive ... Virtual Medical Centre - The Virtual Medical Centre

In utero exposure to valproate tied to poor cognitive outcomes.(Women'...  -  Jan 1, 2007
In utero exposure to valproate tied to poor cognitive outcomes.(Women's Health) ... find Family Practice News articles. SAN DIEGO -- In utero exposure to ... Pay-Per-View - Family Practice News - HighBeam Research

Epilepsy drug shows potential for Alzheimer's treatment  -  Dec 8, 2008
Sodium valproate - which is marketed as the anti-seizure drug Epilim - has been ... Sodium valproate has been used for many years to suppress epileptic ... eurekalert.org

Epilepsy Drug Valproate and Lamotrigine Linked To Malformed Fetus  -  Mar 23, 2005
In a study in the March issue of Neurology, the epilepsy drug Valproate has been linked to malformation of fetus when prescribed to pregnant ladies. ... MedIndia

… ; Chronic myeloid leukemia imatinib treatment enhanced by valproate  -  May 17, 2006
Interactions between imatinib and valproate have been examined in imatinib-sensitive ... Coexposure of cells to valproate and imatinib was associated with ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Panel to MDs: avoid valproate in fertile women.(Neuropsychiatric …  -  Feb 1, 2005
NEW ORLEANS -- Valproate should not be prescribed as first-line therapy for any indication in women of childbearing age because it significantly increases ... Pay-Per-View - Clinical Psychiatry News - Factiva, from Dow Jones

Metaanalysis shows benefit of valproate in bipolar childrens' manic …  -  Jun 1, 2005
Metaanalysis shows benefit of valproate in bipolar childrens' manic symptoms.(Child/Adolescent Psychiatry)(Brief Article) ... find Clinical Psychiatry News ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Switching patients from valproate may reverse hormonal PCOS.  -  Jun 1, 2005
Breckenridge, Colo. -- Hormonal evidence of polycystic ovary syndrome in patients on valproate is often reversed by a switch to one of the newer ... Pay-Per-View - Family Practice News - Factiva, from Dow Jones

Switching patients from valproate may reverse hormonal PCOS. |...  -  Jun 1, 2005
Switching patients from valproate may reverse hormonal PCOS. ... find Family Practice News articles. Breckenridge, Colo. -- Hormonal evidence of polycystic ... Pay-Per-View - Family Practice News - HighBeam Research

… -birth defect link seen only in valproate combo.(Obstetrics) |...  -  Feb 15, 2006
Lamotrigine-birth defect link seen only in valproate combo.(Obstetrics) ... find OB GYN News articles. WASHINGTON -- There is no evidence that lamotrigine ... Pay-Per-View - OB GYN News - HighBeam Research

Endoplasmic Reticulum; ER stress-induced changes studied, valproate …  -  Apr 19, 2005
..."We show that exposure to valproate increases the expression of chaperones ... However, exposure of HepG2 cells to valproate does not decrease the apparent ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Research brief: Sodium valproate causes developmental delays.(Brief …  -  Jul 1, 2005
Women who take sodium valproate during pregnancy increase their child's risk of developmental delays, according to research presented at the annual meeting ... Free with registration - GP - AccessMyLibrary.com

… algorithm facilitates conversion from valproate to lamotrigine...  -  Apr 13, 2005
2005 APR 13 - (NewsRx.com) -- A novel dosing algorithm improves the safety of epilepsy patients converting from valproate to lamotrigine therapy. ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

… algorithm facilitates conversion from valproate to lamotrigine...  -  Apr 11, 2005
2005 APR 11 - (NewsRx.com) -- A novel dosing algorithm improves the safety of epilepsy patients converting from valproate to lamotrigine therapy. ... Pay-Per-View - Pain & Central Nervous System Week - Factiva, from Dow Jones

Endoplasmic Reticulum; ER stress-induced changes studied, valproate …  -  Apr 23, 2005
..."We show that exposure to valproate increases the expression of chaperones ... However, exposure of HepG2 cells to valproate does not decrease the apparent ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Endoplasmic Reticulum; ER stress-induced changes studied, valproate …  -  Apr 18, 2005
..."We show that exposure to valproate increases the expression of chaperones ... However, exposure of HepG2 cells to valproate does not decrease the apparent ... Pay-Per-View - Proteomics Weekly - Factiva, from Dow Jones

… algorithm facilitates conversion from valproate to lamotrigine...  -  Apr 16, 2005
2005 APR 16 - (NewsRx.com) -- A novel dosing algorithm improves the safety of epilepsy patients converting from valproate to lamotrigine therapy. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Valproate, antipsychotic drugs and HAART have additional endocrine …  -  Feb 1, 2006
...by Alan Sacerdote, MD, FACP. It is now well-known that the above drugs are associated with the development of metabolic syndrome. ... Endocrine Today

Depakote Oral : Uses, Side Effects, Interactions, Pictures, Warnings...  -  Jul 12, 2006
Ring chromosome 20, hypersensitivity to valproate and hyperammonemic ... Panda S, Radhakrishnan K. Two cases of valproate-induced hyperammonemic ... WebMD

Prolonged molecular remission in PML-RAR-positive acute promyelocytic...  -  Jul 21, 2005
5 Moreover, in a more recent study, sodium valproate was shown to induce ... This was treated with phenytoin and on day 68 sodium valproate was added to ... Nature.com

Panel to MDs: avoid valproate in fertile women.(Neuropsychiatric …  -  Feb 1, 2005
Panel to MDs: avoid valproate in fertile women.(Neuropsychiatric Medicine) ... find Clinical Psychiatry News articles. NEW ORLEANS -- Valproate should not ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Apoptosis; Valproate increased Ara-C cytotoxicity in acute myeloblasti...  -  Dec 6, 2005
2005 DEC 6 - (NewsRx.com) -- Valproate increased cytarabine (Ara-C) cytotoxicity in acute myeloblastic leukemia (AML) cells. "The effects of valproate and ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Research Finds Newer Drug For Partial Epilepsy Is Superior,But Old...  -  Mar 29, 2007
However valproate remains the most clinically effective drug for ... In generalised epilepsy, valproate was compared with lamotrigine and topiramate. ... Medical News Today - Medical News Today (press release)

Cancer Therapy; Valproate activates bovine leukemia virus gene …  -  Dec 12, 2005
2005 DEC 12 - (NewsRx.com) -- Valproate activates bovine leukemia virus gene expression and induces leukemia/lymphoma regression. ... Pay-Per-View - Hematology Week - Factiva, from Dow Jones

Cancer Therapy; Valproate activates bovine leukemia virus gene …  -  Dec 16, 2005
2005 DEC 16 - (NewsRx.com) -- Valproate activates bovine leukemia virus gene expression and induces leukemia/lymphoma regression. ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

New, easier-to-swallow capsule approved to treat bipolar disorder.  -  Sep 15, 2008
The manufacturer-conducted survey of 400 valproate users has reported that ... Both studies had initiated valproate doses of 250 mg TID and titrated doses ... $9.94 - Drug Topics - Alacra Store

Article: Drops in use of valproate linked to fewer Australian birth...  -  Mar 1, 2006
Drops in use of valproate linked to fewer Australian birth defects.(Obstetrics) ... find OB GYN News articles. WASHINGTON -- Decreased use of valproate to ... Pay-Per-View - OB GYN News - HighBeam Research

… ; Cortical hyperexcitability characterized before and after valproat...  -  Apr 24, 2005
..."Nine patients were prescribed valproate (Depakote) for migraine prophylaxis," explained SM Bowyer and coauthors at the Henry Ford Health System in Detroit. ... Pay-Per-View - Medical Devices & Surgical Technology... - Factiva, from Dow Jones

Birth defects decline as valproate is used less.(Women's Health) |...  -  Feb 15, 2006
Birth defects decline as valproate is used less.(Women's Health) ... find Internal Medicine News articles. WASHINGTON -- Decreased use of valproate to ... Pay-Per-View - Internal Medicine News - HighBeam Research

… ; Cortical hyperexcitability characterized before and after valproat...  -  Apr 18, 2005
..."Nine patients were prescribed valproate (Depakote) for migraine prophylaxis," explained SM Bowyer and coauthors at the Henry Ford Health System in Detroit. ... Pay-Per-View - Pain & Central Nervous System Week - Factiva, from Dow Jones

Article: Valproate may help child with bipolar disorder.(Behavioral …  -  May 1, 2005
Valproate may help child with bipolar disorder.(Behavioral Pediatrics)(Brief Article) ... find Pediatric News articles. ATLANTA -- Valproate appears to have ... Pay-Per-View - Pediatric News - HighBeam Research

Defect rate drops with reduced use of valproate in Australia.(dosages)...  -  Mar 1, 2006
Defect rate drops with reduced use of valproate in Australia.(dosages)(Statistical data) ... find Clinical Psychiatry News articles. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

… ; Cortical hyperexcitability characterized before and after valproat...  -  Apr 19, 2005
..."Nine patients were prescribed valproate (Depakote) for migraine prophylaxis," explained SM Bowyer and coauthors at the Henry Ford Health System in Detroit. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Avoid valproate in fertile women, expert panel recommends.(News) | …  -  Mar 1, 2005
Avoid valproate in fertile women, expert panel recommends.(News) ... find Family Practice News articles. NEW ORLEANS -- Valproate should not be prescribed ... Pay-Per-View - Family Practice News - HighBeam Research

Article: MDs urged to avoid valproate in fertile women: risk of major...  -  Jan 1, 2005
MDs urged to avoid valproate in fertile women: risk of major fetal malformations cited.(News) ... find OB GYN News articles. NEW ORLEANS -- Valproate should ... Pay-Per-View - OB GYN News - HighBeam Research

Article: Epilepsy drug could have caused death of children.(News) - …  -  Nov 18, 2005
Midha Background: Sodium valproate is among the newer mood stabilizers ... To assess the effect of intravenous sodium valproate in patients with acute manic ... Pay-Per-View - Western Mail - HighBeam Research

Article: Valproate linked to poor fetal outcomes.(Women's Health) - …  -  Dec 15, 2006
Valproate linked to poor fetal outcomes.(Women's Health) ... find Internal Medicine News articles. Valproate poses by far the greatest teratogenic risk of ... Pay-Per-View - Internal Medicine News - HighBeam Research

Article: Avoid valproate as first-line Tx in fertile women.(Neurology)...  -  Jan 15, 2005
Avoid valproate as first-line Tx in fertile women.(Neurology) ... find Internal Medicine News articles. NEW ORLEANS -- Valproate should not be prescribed as ... Pay-Per-View - Internal Medicine News - HighBeam Research

… EQUETRO in Patients with Bipolar I Disorder Previously Taking Valpro...  -  May 24, 2005
Specifically, patients previously taking valproate had a reduction in their average YMRS scores by 10.8 on EQUETRO vs. 5.7 on placebo (p=0.04), ... $4.95 - PR Newswire - ECNext

Article: Weight gain on valproate often normal growth.(Clinical...  -  Apr 1, 2006
Weight gain on valproate often normal growth.(Clinical Rounds) ... find Pediatric News articles. LOS ANGELES -- Children taking sodium valproate for ... Pay-Per-View - Pediatric News - HighBeam Research

The Telegraph - Calcutta (Kolkata) | KnowHOW | Drug dilemma  -  Jul 28, 2008
Valproate, which is one of the most common drugs used in treating the problem, has previously been associated with birth defects or foetal death in about 20 ... Calcutta Telegraph

Court action over sodium valproate  -  May 25, 2006
GPs have been advised to take extra caution over the use of sodium valproate in women of childbearing age after a major court case began against the drug's ... Pay-Per-View - Pulse - Factiva, from Dow Jones

Article: Lamotrigine + valproate linked to birth defects.(Women's...  -  May 15, 2006
Lamotrigine + valproate linked to birth defects.(Women's Health) ... find Internal Medicine News articles. WASHINGTON -- There is no evidence that ... Pay-Per-View - Internal Medicine News - HighBeam Research

Women and Epilepsy: Pregnancy Registries Yield Valuable Information  -  Jan 5, 2005
However, the results are consistent with higher rates for valproate reported at the ... Outcomes were worse for valproate in all 7 studies even though the ... Medscape

Dearth of evidence supporting non-epileptic uses of antiepileptic …  -  Sep 1, 2006
Valproate is "probably effective" in decreasing aggressive behavior and, ... While finding some evidence of effectiveness for valproate in decreasing ... Free with registration - Brown University Child and Adolescent... - AccessMyLibrary.com

Pharmacokinetic and Pharmacodynamic Interaction of Lorazepam and …  -  May 8, 2007
Pharmacokinetic and pharmacodynamic profiles of lorazepam and valproate were analyzed ... AUCs of valproate showed an increasing tendency as the number of ... Nature.com

Illinois Administrative Code - 77 Ill. Adm. Code 790.9475 VALPROATE …  -  Aug 10, 2005
77 Ill. Adm. Code 790.9475 VALPROATE SODIUM (Repealed) Repealed. (Source: Repealed at 17 Ill. Reg. 15916, effective September 20, 1993) ... Pay-Per-View - Illinois Administrative Code - Loislaw

No need to rush to take epilepsy drugs  -  Jun 12, 2005
Half of the group were given antiepileptic drugs carbamazepine or valproate immediately, while the other half did not receive any treatment until they and ... News-Medical.net





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