Vaseretic

This page contains recent news articles, when available, and an overview of Vaseretic but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Vaseretic
(when available)

Pharmacology and use:
Thiazides promote water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue. For the treatment of high blood pressure and management of edema

Mechanism Of Action:
As a diuretic, Hydrochlorothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like Hydrochlorothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter. This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. The antihypertensive mechanism of Hydrochlorothiazide is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium (KCa) channel, also found in the smooth muscle.

News Articles on Hydrochlorothiazide

Merck Announces Third-Quarter 2009 Financial Results  -  ‎Oct 22, 2009‎
INVANZ, ISENTRESS, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN, TIMOPTIC/TIMOPTIC XE, TREDAPTIVE, TRUSOPT, VASOTEC/VASERETIC, ZOCOR and ZOLINZA. ... Reuters

Vaseretic.(Drug overview)  -  Jan 22, 2007
Vaseretic is used in the treatment of high blood pressure. It combines an ACE inhibitor with a thiazide diuretic. Enalapril, the ACE inhibitor, ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Biovail to spin off 'legacy' drugs; pays first dividend  -  Nov 15, 2005
Biovail's off-patent products include the Cardizem CD, Ativan, Vaseretic, Vasotec, Isordil and Tiazac in the United States, and Cardizem CD in Canada. ... CBC.ca

Competitors by Product Report  -  Mar 29, 2008
Vaseretic (Enalapril Maleate/Hydrochlorothiazide) ... Prinzide (Lisinopril/Hydrochlorothiazide); Vaseretic (Enalapril Maleate/Hydrochlorothiazide) ... $75.00 - Revere Reports - Revere

Learn about the World Hypertension Market 2007-2023.  -  Feb 6, 2008
7.4 Vasotec/Vaseretic - This Older Drug Will Face Decline ... Figure 7.7, World Vasotec/Vaseretic Revenues ($m), 2006-2023 Figure 7.8, World Revenues ($m) ... Free with registration - Business Wire - AccessMyLibrary.com

Diabetes Drug Also Preventive; Avandia Reduces Risk of Developing …  -  Sep 16, 2006
Altace from Hoechst-Roussel Pharmaceuticals; Zestril and Zestoretic by ICI Pharmaceuticals Group; Vasotec, Vasotec I.V., Vaseretic ... ... Pay-Per-View - Washington Post - HighBeam Research

DRUGS CAN DILUTE BODY'S VITAMIN B6  -  Sep 17, 2008
Other medications on the drug mugger list for vitamin B6 include HCTZ, Vaseretic, Dyazide, Maxzide, EVISTA, hormone replacement drugs containing estradiol, ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

Bentley Announces Product Approvals in Spain and Ireland.  -  Oct 29, 2007
The product is marketed in the United States by Merck & Co. under the trade name, Vaseretic([R]). The Spanish market size for enalapril with HCTZ is ... Free with registration - Business Wire - AccessMyLibrary.com

Biovail to Spin off Legacy Assets  -  Nov 15, 2005
Biovail's Legacy assets include the well-known brands Cardizem ® CD, Ativan ® , Vaseretic ® , Vasotec ® , Isordil ® and Tiazac ® in the United States and ... ccnmatthews.com

Merck launches restructuring  -  Dec 5, 2005
...facility, which makes products including the cholesterol-lowering drug Mevacor and the blood pressure drugs Vasotec and Vaseretic, will cease this month ... ICIS

Merger and Acquisition Scenario  -  Mar 11, 2006
Vaseretic (Enalapril Maleate/Hydrochlorothiazide). Calcium Channel Blocking Agents. Therapeutics that treat high blood pressure by blocking the beta ... $250.00 - Revere Reports - Revere

Eplerenone (Systemic).  -  Oct 27, 2005
Angiotensin-converting enzyme (ACE) inhibitors (Benazepril [eg, Lotensin], captopril [eg, Capoten, Capozide], enalapril [eg, Lexxel, Teczem, Vaseretic, ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Merger and Acquisition Scenario  -  Dec 29, 2007
...potassium ions, and water through urine. Buyer Products:. Vaseretic (Enalapril Maleate/Hydrochlorothiazide). Calcium Channel Blocking Agents. $250.00 - Revere Reports - Revere

Press Release: Ground-breaking Research Unveiled Today at Top …  -  Nov 6, 2006
BY FDA NOW AVAILABLE WHAT: Luncheon news briefing to announce the availability of Vaseretic ... characteristics.) WHERE: The luncheon news briefing will be ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  Mar 9, 2006
Vaseretic (Enalapril Maleate/Hydrochlorothiazide). Calcium Channel Blocking Agents. Therapeutics that treat high blood pressure by blocking the beta ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Apr 7, 2007
...and increasing the excretion of sodium ions, potassium ions, and water through urine. Buyer Products:. Vaseretic (Enalapril Maleate/Hydrochlorothiazide) $250.00 - Revere Reports - Revere

Company Profile Report  -  Apr 5, 2008
Vaseretic (Enalapril Maleate/Hydrochlorothiazide); Prinzide (Lisinopril/Hydrochlorothiazide). Angiotensin II Receptor Antagonists ... $50.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Jan 26, 2008
...potassium ions, and water through urine. Target Products:. Vaseretic (Enalapril Maleate/Hydrochlorothiazide). Calcium Channel Blocking Agents. $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Aug 25, 2007
...potassium ions, and water through urine. Buyer Products:. Vaseretic (Enalapril Maleate/Hydrochlorothiazide). Calcium Channel Blocking Agents. $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Sep 6, 2008
...the excretion of sodium ions, potassium ions, and water through urine. Buyer Products:. Vaseretic (Enalapril Maleate/Hydrochlorothiazide). Calcium Chann. $250.00 - Revere Reports - Revere

In- Depth Research on Biovail Corp.  -  Apr 3, 2007
Vasotec and Vaseretic for the treatment of hypertension, symptomatic congestive heart failure, and asymptomatic left ventricular dysfunction; Tiazac; ... $4.95 - M2 Presswire - ECNext

Biovail va essaimer des produits  -  Nov 15, 2005
En plus du Cardizem au Canada et du Tiazan aux États-Unis, la liste comprend les produits Ativan, Vaseretic, Vasotec et Isordil. ... Le Journal de Québec

Merger and Acquisition Scenario  -  Sep 6, 2008
...renin-angiotensin system and increasing the excretion of sodium ions, potassium ions, and water through urine. Buyer Products:. Vaseretic (Enalapril Mal. $250.00 - Revere Reports - Revere

Minnesota - Official Notices - Department of Human Services  -  Jan 3, 2006
Vaseretic Monopril HCT Zestoretic Dihydropyridine calcium channel blockers Adalat Adalat CC Procardia Procardia XL Cardene Cardene SR Nimotop ... Pay-Per-View - RegAlert - Factiva, from Dow Jones

Merger and Acquisition Scenario  -  Sep 6, 2008
Vaseretic (Enalapril Maleate/Hydrochlorothiazide). Calcium Channel Blocking Agents. Therapeutics that treat high blood pressure by blocking the beta ... $250.00 - Revere Reports - Revere

New York Miscellaneous Reports - IN RE APPL. OF GOODACRE v. …  -  Nov 18, 2008
The report then details the various medications Goodacre was on, including sublingual nitroglycerin, Plavix, Imdur, Topiol, Vaseretic, Lipitor and aspirin. ... Pay-Per-View - New York Miscellaneous Reports - Loislaw

Brand Names/Synonyms:
Vaseretic is also known by the following brand names and/or synonymsAcuretic; Aldactazide; Aldoril; Apresazide; Aquarills; Aquarius; Bremil; Caplaril; Capozide; Chlorosulthiadil; Chlorothiazide; Chlorsulfonamidodihydrobenzothiadiazine Dioxide; Chlorzide; Cidrex; Dichlorosal; Dichlorotride; Dichlotiazid; Dichlotride; Diclotride; Dicyclotride; Dihydrochlorothiazid; Dihydrochlorothiazide; Dihydrochlorothiazidum; Dihydrochlorurit; Dihydrochlorurite; Dihydroxychlorothiazidum; Direma; Disalunil; Diu-Melusin; Diuril; Drenol; Dyazide; Esidrex; Esidrix; Esimil; Fluvin; H.H. 25/25; H.H. 50/50; HCTZ; HCZ; Hidril; Hidrochlortiazid; Hidroronol; Hidrotiazida; Hydril; Hydro-Aquil; Hydro-D; Hydro-Diuril; Hydrochlorothiazid; Hydrochlorothiazide; Hydrochlorothiazide Intensol; Hydrochlorthiazide; Hydrodiuretic; Hydrodiuril; Hydropres; Hydrosaluric; Hydrothide; Hydrozide; Hypothiazid; Hypothiazide; Hyzaar; Idrotiazide; Inderide; Ivaugan; Jen-Diril; Lopressor Hct; Lotensin Hct; Maschitt; Maxzide; Megadiuril; Microzide; Moduretic; Nefrix; Neo-Codema; Neoflumen; Newtolide; Oretic; Palonyl; Panurin; Perovex; Primogyn; Prinzide; Ro-Hydrazide; Servithiazid; Su 5879; Thiaretic; Thiazide, Hydrochloro-; Thiuretic; Thlaretic; Timolide; Unipres; Urodiazin; Vaseretic; Vetidrex; Ziac; Zide

Drug Category:
Vaseretic is categorized under the following by the FDA: Diuretics; Antihypertensive Agents; ATC:C03AA03

Dosage Forms:
Oral tablets, various strength

Absorption:
50-60%

Interactions:
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Chemical IUPAC Name:
9-chloro-5,5-dioxo-5$l^{6}-thia-2,4-diazabicyclo[4.4.0]deca-6,8,10-triene-8-sulfonamide





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