Viagra

This page contains recent news articles, when available, and an overview of Viagra but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Viagra
(when available)

Pharmacology and use:
Sildenafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum. This then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased inflow of blood and an erection. Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. This means that, with Sildenafil on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, Sildenafil should not cause an erection. For the treatment of erectile dysfunction

Mechanism Of Action:
Sildenafil inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by Sildenafil enhances erectile function by increasing the amount of cGMP.

News Articles on Sildenafil

German firm developing 'female Viagra'  -  14 Nov 2009
New York-based Pfizer, maker of the male impotency drug Viagra, had been trying for years to unlock the mysteries of female sexual desire, but failed to ... Trading Markets (press release)

German company plans to market low-cost Viagra  -  14 Nov 2009
Hamburg - A German company is preparing to manufacture a copy of the erectile-dysfunction medicine Viagra as soon as the patent in Germany runs out, ... Monsters and Critics.com

Viagra Strike Breaker  -  14 Nov 2009
The power of Viagra has been highlighted in a recent case where it was used to break a transport strike in Philadelphia USA. The drivers who work on the ... UKMedix Health News

Weird news this week  -  14 Nov 2009
Viagra. The pudding-like dessert, Canoe reports, is topped with whipped cream and chocolate and served in a parfait glass. One of the creators said they ... Blast

Grey New World  -  14 Nov 2009
From Pablum to Viagra, boomers have been demographic game changers. How will they handle the leap into old age? By SHEILA MCGOVERN, The GazetteNovember 14, ... The Gazette (Montreal)

Kelo: Pfizer forever linked with eminent domain 'theft': Plaintiff says ...  -  14 Nov 2009
..."They're not going to be thinking about Viagra." Pfizer consistently has denied any connection between corporate policy and eminent domain. ... Trading Markets (press release)

Swine flu blog: Black elderberry - the latest miracle cure  -  14 Nov 2009
...but it's not been too surprising to see emails in my inbox with a subject line about swine flu which is just an advert for Viagra or some miracle cure. ... Whitehaven News

Colombia chef school concocts dessert with Viagra  -  ‎Nov 13, 2009‎
BOGOTA — A Colombian cooking school has concocted a "love dessert" made with passion fruit — and Viagra. Student chefs at the state culinary school in ... The Associated Press

Stupak's Flaccid Amendment Needs No Viagra  -  ‎Nov 12, 2009‎
Oh, yes, it's time. With the House passing a health care bill with the Stupak Amendment, we really need to start talking about this. ... Huffington Post (blog)

N. Providence store owner admits to illegally selling Viagra  -  ‎Nov 12, 2009‎
...in federal court Tuesday to charges that he sold illegal generic Viagra, pirated movies and installed computer software without paying license fees. ... Providence Journal

FDA Approve Female 'Viagra', 4-hr Erection Notice Remains  -  ‎Nov 13, 2009‎
Rusty… Numerous associates who have noticed this piece take exception to your deriding the Poxo_Klit_Slime Corporation formulation known as SexaFem. ... Glossy News (satire)

Philly Strike Ends After Workers Awarded One Viagra Per Day  -  ‎Nov 12, 2009‎
They even threatened to walk out during the World Series in order to have their way, which included one-a-day supply of viagra. Funded by the taxpayer of ... The Business Insider

As Boehringer Develops Viagra for Women, History Suggests High Risk of Failure  -  ‎Nov 13, 2009‎
Boehringer has developed a bunch of cutesy names for its clinical trials: “Violet,� “Daisy,� “Dahlia� and “Orchid. ... BNET

Viagra Maker Hard On St. Louis; Pfizer Announces It Will Slash 600 Local Jobs  -  ‎Nov 10, 2009‎
...​Yesterday, Pfizer (maker of Viagra, Celebrex, Lipitor and countless other drugs whose advertisements pay for the network evening news) announced that it ... Riverfront Times

'All-natural' sex pill contains Viagra chemical: FDA  -  ‎Nov 5, 2009‎
The investigation found that rather than being all-natural, Stiff Nights contains sulfoaildenafil, a chemical similar to the ingredient in Viagra. ... AFP

SC Ghoulish Sexploits: Take a Stripper, Sex Toys, Viagra to Cemetery  -  ‎Oct 29, 2009‎
Anyone can do it, as long as you are an elderly Republican right-wing state official with a libido revived by Viagra. With a rekindled libido in hand, ... ChattahBox

BBC iPlayer compared to Viagra  -  ‎Nov 11, 2009‎
The BBC iPlayer has been compared to innovations including the steam engine, jet engine and Viagra by judges. By Urmee Khan, Digital and Media Correspondent ... Telegraph.co.uk

'Women's Viagra' Targets Her ... Brain  -  ‎Nov 13, 2009‎
The pill, which the company says works by triggering the production of dopamine, has the potential to revolutionize sexual medicine as much as Viagra did. ... Newser

Studies show Viagra, other drugs outperform hormone treatment  -  ‎Oct 20, 2009‎
...the American College of Physicians has officially proclaimed the superiority of drugs such as Viagra, Levitra and Cialis over hormone treatment. ... Los Angeles Times

Fake Viagra pills seized at Miami International Airport  -  ‎Oct 23, 2009‎
US Customs and Border Protection officers at the Miami International Airport intercepted 21600 counterfeit Viagra pills that weighed a total of 50 pounds. ... MiamiHerald.com

Pfizer Drug Studies Misleading - Again  -  ‎Nov 12, 2009‎
Drug giants Pfizer Inc. who make Viagra and Zoloft, are misleading consumers once again according to a report that discovered when a company-funded study's ... eMaxHealth

Councilors saved our eyes; now save our lungs  -  ‎Nov 13, 2009‎
I am certain that if Viagra or contraceptives were delivered via smoke, even the so-called conservatives would demand government intervention. ... Ashland Daily Tidings

Will Sex Sell for Chrysler?  -  ‎Nov 11, 2009‎
MI) and almost 10% owned by the US government) finally told the world how it plans to storm back: with a dose of Viagra. At a presentation for auto analysts ... BusinessWeek

HOW I SEE IT: Government health care won't work  -  ‎Nov 13, 2009‎
It is my belief that if you ask any man who takes Viagra if it is not for an illness or possible injury he might just disagree with you and tell you that it ... Culpeper Star Exponent

No daily Viagra dose, no peace! Philly transit workers rise up in protest  -  ‎Nov 7, 2009‎
The striking union of transit workers in Philadelphia are angry that they're not getting daily doses of Viagra. And amazingly, their bosses apparently caved ... Daily Finance (blog)

Where to toss expired Viagra, Vicodin, etc. State will have drop-off sites for ...  -  ‎Nov 7, 2009‎
If you keep forgetting to throw out that bottle of Ritalin that expired in 2005, now's your chance to dispose of it properly, ... The Hudson Reporter

Hacked B-school website has Viagra woes  -  ‎Nov 9, 2009‎
Four days ago, online orders for Viagra found their way into the website of the Faculty of Management Studies (FMS), Delhi, a B-school affiliated to Delhi ... Times of India

The need for Viagra and Cialis might be a clue  -  ‎Nov 8, 2009‎
Could the fact that SO many people are using Viagra-type drugs be an indication that we're desperately resisting a natural transition into a new and ... Examiner.com

Viagra Concession Ends Transit Strike  -  ‎Nov 11, 2009‎
Aahhh, Ms Beckert a fitting piece on our beloved SEPTA (South Eastern Pennsylvania Transportation Authority). Thank you for providing the answer to my ... Glossy News (satire)

Extensive Stash Found After Traffic Stop in Bremerton  -  ‎Nov 13, 2009‎
...patient's name scraped off, 20 Vicodin pills, six oxycodone pills, a baggie with marijuana, two Viagra pills and various other drugs and paraphernalia. ... Kitsap Sun

Chefs unveil Viagra-laced dessert  -  ‎Nov 13, 2009‎
BOGOTA - A GROUP of young Colombian student chefs have unveiled a new dessert made from passion fruit and Viagra, claiming it had aphrodisiac effects on ... Straits Times

Viagra Concession Ends Transit Strike  -  ‎Nov 10, 2009‎
...of their health care costs covered, including full-month prescriptions for Viagra and similar prescription medicines to treat erectile dysfunction (ED). ... Glossy News (satire)

Did Viagra prank get a rise out of Henry?  -  ‎Oct 24, 2009‎
HAVING A LAUGH: Ali Williams recounts a story of Viagra-laced beer in his new book. All Blacks lock Ali Williams ... Stuff.co.nz

Artificial penile tissue improves male rabbits' sex lives and could one day ...  -  ‎Nov 10, 2009‎
So, this would be a Viagra replacement? In 35% of men, Viagra and other impotence drugs don't work, McCullough says. That's because as men age and develop ... New York Daily News

The Artificial Penis Is Tantalizingly Close to Becoming Reality  -  ‎Nov 10, 2009‎
But does this mean the artificial penis will one day be available to humans and possible replace drugs like Viagra? Possibly. "We don't quite understand why ... Cityfile

Why Should Public Dollars Pay for the Vanity of Old Men?  -  ‎Nov 11, 2009‎
Public dollars should no more pay for viagra than for abortion (except for rape or danger to the mpther's health). Its not the taxpayers responsibility. ... The Moderate Voice

The Five Most Unlikely NASCAR Sponsorships  -  ‎Nov 13, 2009‎
Viagra: Because NASCAR is a private company, they can say who is and isn't allowed to advertise with them. The general rule seems to be that if you're ... Seattle Weekly

Transit strike lesson: Learn to drive a bus  -  ‎Nov 6, 2009‎
In fact, the Daily News reported that the proposed contract would have increased coverage of Viagra and other erectile-dysfunction drugs. ... Philadelphia Inquirer

Bruce Springsteen gets rise out of audience with off-color humor  -  ‎Nov 6, 2009‎
..."Pepsi has created a soda that has Viagra in it," he joked between songs at the NY Comedy Festival and Bob Woodruff Foundation event. ... New York Daily News

THG on TV: Thursday Night's Best & Worst  -  ‎Nov 13, 2009‎
A virgin took so much Viagra on his wedding night that he couldn't shed his erection on Private Practice. Seriously. Good news: Meredith returned to work on ... The Hollywood Gossip (blog)

EPD: Man caught with meth & Viagra  -  ‎Oct 22, 2009‎
Officers say they searched Hoffman and found some meth and Viagra in his pocket. A search of his car revealed Sudafed, sniffing straws, lithium batteries ... WFIE-TV

'Oldiewed' gifts  -  ‎Nov 12, 2009‎
Ask your doctor for free samples of Viagra or Cialis. What? Candy OR Iron? Whose idea was that? I guess candy if the couple feels the relationship is going ... Pasadena Weekly

First 'Viagra baby' conceived through IVF using Sildenafil on a woman to aid ...  -  ‎Oct 23, 2009‎
...“I had seen the news reports on Viagra and its ability to increase blood flow to the male organ, so it followed logically that it could do the same for ... eNewsChannels

Viagra's 10th Birthday celebrated in family friendly viral  -  ‎Nov 9, 2009‎
That's just what pharmaceutical giant, Pfizer, has done in a new piece of work that celebrates the tenth birthday of Viagra - the little blue pill that has ... Utalkmarketing

Times Snuggles With Viscount of Viagra: Yuck!  -  ‎Oct 28, 2009‎
The Viscount of Viagra on page one, a women's rights opinion at the end of the section. Definitely the odd couple. The 83-year-old Hefner presents himself ... Women's eNews

Man accused of hiding drugs in storage  -  ‎Nov 6, 2009‎
Al Khurdi then gave investigators consent to search the storage unit where they found more than 5000 dosage units of Lortab, Xanax and Viagra, Graham said. ... 2TheAdvocate

Daily Q&A: What should I consider before buying dietary supplements?  -  ‎Nov 9, 2009‎
The ingredient in Stiff Nights, sulfoaildenafil, can cause serious injury or death, the FDA said. The active ingredient in Viagra is sildenafil. Tampabay.com

Cost-Cutting Helps Pfizer Overcome Lower Sales  -  ‎Oct 20, 2009‎
Pfizer, which makes the cholesterol treatment Lipitor, the impotence treatment Viagra and the smoking cessation drug Chantix, slashed costs in manufacturing ... New York Times

Idiot Box: Lower learning  -  ‎Nov 11, 2009‎
...(I did mention the Beastmaster-on-Viagra episode, didn't I?) Here's hoping NBC gives it the benefit of the doubt as opposed to the quick ax. ... Weekly Alibi

Viagra soup  -  ‎Oct 22, 2009‎
Would you pay 32 dollars for a bowl of soup? Even if it was sure to get you and your significant other in the mood for love? ... Fox11online.com

Brand Names/Synonyms:
Viagra is also known by the following brand names and/or synonyms:
Sildenafil; Sildenafil Viagra; Viagra

Drug Category:
Viagra is categorized under the following by the FDA: Vasodilator Agents; Phosphodiesterase Inhibitors; ATC:G04BE03

Dosage Forms:
TABLET

Absorption:
~40%

Interactions:
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Chemical IUPAC Name:
3-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-7-methyl-9-propyl-2,4,7,8-tetrazabicyclo[4.3.0]nona-3,8,10-trien-5-one





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