Videx EC

This page contains recent news articles, when available, and an overview of Videx EC but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Videx EC
(when available)

Pharmacology and use:
Didanosine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Didanosine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated. For treatment of Human immunovirus (HIV) infections

Mechanism Of Action:
Didanosine (ddI) is metabolized intracellularly by a series of cellular enzymes to its active moiety, 2,3–dideoxyadenosine-5-triphosphate (ddA-TP), which inhibits HIV DNA polymerase (reverse transcriptase). Didanosine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.

News Articles on Didanosine

HIV Therapy; Generic version of Videx EC antiretroviral agent...  -  Jan 23, 2005
2005 JAN 23 - (NewsRx.com & NewsRx.net) -- Barr Pharmaceuticals, Inc., (BRL) announced that its subsidiary, Barr Laboratories, Inc., has received approval ... Pay-Per-View - Medical Letter on the CDC & FDA - Factiva, from Dow Jones

HIV Therapy; Generic version of Videx EC antiretroviral agent...  -  Jan 17, 2005
2005 JAN 17 - (NewsRx.com & NewsRx.net) -- Barr Pharmaceuticals, Inc., (BRL) announced that its subsidiary, Barr Laboratories, Inc., has received approval ... Pay-Per-View - Pharma Business Week - Factiva, from Dow Jones

FDA approves generic version of Videx EC delayed release capsules.( …  -  Apr 1, 2005
FDA approves generic version of Videx EC delayed release capsules.(Food and Drug Administration of the United States)(Brief Article) ... find HIV Treatment: ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

HIV Therapy; Generic version of Videx EC antiretroviral agent...  -  Jan 19, 2005
2005 JAN 19 - (NewsRx.com & NewsRx.net) -- Barr Pharmaceuticals, Inc., (BRL) announced that its subsidiary, Barr Laboratories, Inc., has received approval ... Pay-Per-View - Immunotherapy Weekly - Factiva, from Dow Jones

FDA approves generic version of Videx EC delayed release capsules.( …  -  Apr 1, 2005
In December 2004, the FDA approved a generic version of Didanosine (ddl) Delayed Release capsules (200 mg, 250 mg, and 400 mg) to use in combination with ... $4.95 - HIV Treatment: ALERTS! - ECNext

Article: Videx.(PRODUCT REVIEW: SECURITY PRODUCTS) - American …  -  Jun 1, 2008
VIDEX EC Provides Convenience with Improved Tolerability ... Results from a 48-week study demonstrate that VIDEX EC (didanosine) capsules had similar ... Pay-Per-View - American Coin-Op - HighBeam Research

Article: Videx Inc.(SECURITY PRODUCTS) - Automatic Merchandiser | …  -  Jan 1, 2006
VIDEX EC Provides Convenience with Improved Tolerability ... Results from a 48-week study demonstrate that VIDEX EC (didanosine) capsules had similar ... Pay-Per-View - Automatic Merchandiser - HighBeam Research

Videx y Videx EC (didanosine, ddI)  -  Mar 1, 2008
Videx y Videx EC son medicamentos anti-VIH, que pertenecen a la categoría de los inhibidores nucleósidos de la transcriptasa reversa (INTR). ... AIDSmeds.com HIV/AIDS Treatment News

Tarnished hydroxyurea less toxic, more potent at lower doses,...  -  Apr 26, 2005
...gain when taken alongside ddI (didanosine, Videx EC), according to new data from the Research Institute for Genetic and Human Therapy (RIGHT) in Pavia, ... Aidsmap

Ã?ndice de lecciones  -  Mar 1, 2008
Si estás recibiendo Viread y Videx EC ya sea junto con Sustiva o Viramune, deberías consultar ... Viread aumenta la cantidad de Videx/Videx EC en el cuerpo. ... AIDSmeds.com HIV/AIDS Treatment News

Inhoud van deze bijsluiter  -  Mar 11, 2005
Videx EC capsules zijn bestemd voor de behandeling van patienten met ... Het geven van borstvoeding tijdens de Videx EC behandeling wordt afgeraden. ... Consumed

Hivid (zalcitabine o ddC)  -  Jan 29, 2007
Entre ellos se encuentran: Videx®/Videx EC® (ddI), Zerit® (d4T), isoniazid (usado para prevenir y tratar la tuberculosis) y diversos medicamentos de ... AIDSmeds.com HIV/AIDS Treatment News

Caution: combination of Viread, Videx, and either Sustiva or Viramune....  -  Apr 1, 2005
Article: FDA approves generic version of Videx EC delayed release ... ... The delayed-release version of Videx ("Videx EC") was developed in 2001 as an ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

Aurobindo drug gets FDA nod  -  Sep 27, 2008
It is the generic version of Bristol Myer Squibb's Videx EC (Didanosine) delayed-release capsules. This was the 78th Abbreviated New Drug Application from ... Hindu Business Line

Aurobindo gets US nod for Bristol's Videx generic  -  Sep 25, 2008
The drug is the generic version of Bristol-Myers Squibb's Videx EC and is used to treat HIV infection in adults, Aurobindo said in a statement. Hindu Business Line

Closing Bell- Market Live-Stocks-Markets-The Economic Times  -  Sep 25, 2008
Didanosine delayed release capsules is the generic of Bristol Myer Squibb's Videx EC capsules and is indicated for the treatment of HIV-1 infections in ... Economic Times

CROI: Simplified treatment regimens show promise in HIV-infected …  -  Feb 7, 2006
They treated the patients with a once-daily regimen of three anti-HIV drugs comprising ddI (didanosine, Videx / Videx EC), FTC (emtricitabine, Emtriva) and ... Aidsmap

Study Explores Lipid Problems in Women  -  May 8, 2007
...by Tim Horn. New data indicate that lipid problems can vary, depending on a woman's HIV status, whether or not she's on HIV treatment, ... AIDSmeds.com HIV/AIDS Treatment News

Triple nuke combination of AZT/3TC/tenofovir below current standards...  -  Dec 18, 2006
Despite reports emerging in 2003 that tenofovir/3TC in combination with abacavir (Ziagen) or ddI (didanosine, Videx/Videx EC) had a high rate of early ... Aidsmap

Conflicting pharmacokinetic results when lopinavir and atazanavir are...  -  Jun 6, 2006
After at least a month of Kaletra/atazanavir therapy - taken with a background regimen that included tenofovir, or ddI (Videx EC), or T20 (Fuzeon), ... Aidsmap

Better than expected 'real world' benefits seen in highly treatment- …  -  Jun 22, 2006
The nucleoside background combination was similar to the 045 study, with two-thirds on tenofovir (Viread) and ddI (Videx EC). ... Aidsmap

Fatty liver prevalence high with HIV/HCV coinfection: 'use ddI or d4T...  -  Jun 30, 2006
Individuals coinfected with HIV and hepatitis C virus (HCV) should use ddI (didanosine, Videx/Videx EC) and d4T (stavudine, Zerit) with caution, ... Aidsmap

Prescription drugs can deliver high doses of phthalates  -  Nov 10, 2008
Another 121 people who took three other medications--omeprazole, used in Prilosec antacids; didanosine, which is sold under the name Videx EC and treats HIV ... Environmental Health News

Next generation NRTI, DFC (Reverset) discontinued due to safety …  -  Apr 11, 2006
Study 203 had found that a combination of DFC with ddI (didanosine, Videx/Videx EC) led to a 50% incidence rate of grade 4 hyperlipasaemia, with seven of ... Aidsmap

ART Drug Interactions: Expert Interview w/ Dr. Corky Steinhart  -  Mar 4, 2005
...a very important question regarding the interaction between these 2 popular, user-friendly drugs, tenofovir ( Viread ) and didanosine ( Videx EC ). ... Medscape

Multi-component drug delivery system: An emerging trend  -  Feb 15, 2006
...lamivudine/zidovudine (Combivir), stavudine, d4T (Zerit), didanosine, ddI (Videx, Videx EC), zalcitabine, ddC (HIVID), and zidovudine, AZT (Retrovir). ... expresspharmapulse.com

Reckoning the Risk: Abacavir, Didanosine and Heart Attacks in the...  -  Feb 26, 2008
Epzicom and Trivizir) and didanosine (used in Videx tablets and Videx EC capsules)—significantly increased the risk of a heart attack, despite the fact ... AIDSmeds.com HIV/AIDS Treatment News

Barr Pharmaceuticals "strong buy," target price raised  -  Jul 24, 2008
The analyst expects Barr Pharmaceuticals' performance to be robust in FY06 due to the recent launch of the company's major products DDAVP, Videx EC and ... newratings.com

US approves Pegasys with ribavirin for chronic HCV in HIV/HCV …  -  Mar 4, 2005
All 14 were taking nucleoside reverse transcriptase inhibitors (NRTIs), including stavudine (d4T, Zerit), didanosine (ddI, Videx EC), abacavir (Ziagen), ... Aidsmap

Abacavir, Didanosine Linked to Increased Heart Attack Risk  -  Feb 4, 2008
...attack risk associated with current use of didanosine (Videx EC) but not other drugs in the nucleoside reverse transcriptase inhibitor (NRTI) class, ... AIDSmeds.com HIV/AIDS Treatment News

Side-effects major reason UK patients switch from first-line therapy,...  -  Oct 21, 2005
Fourteen were on 3TC (lamivudine, Epivir) before the switch, eight were on d4T, and five were on ddl (didanosine, Videx/Videx EC). ... Aidsmap

Sending AIDS drugs around the world from a storage room on Greenwich ...  -  Mar 24, 2005
...“Right now, we're running low on Videx EC (400 mg), but on the other hand, we have a lot of Crixivan,� explains Dr. Jaime Valencia, the organization's staff ... Downtown Express

HHS issues updated HIV guidelines.(Health & Human Services)( …  -  Nov 21, 2005
One addition to the list is the combination of didanosine (Videx EC, Bristol-Myers Squibb) and tenofovir (Viread, Gilead). The guidelines now state, ... Free with registration - Drug Topics - AccessMyLibrary.com

Article: Suspect Additive Commonly Used in China - AP Online | …  -  Apr 30, 2007
Article: FDA approves generic version of Videx EC delayed release ... HIV Treatment: ALERTS!; April 1, 2005 ; 700+ words ... ... alternative to the original ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

New generics.(Rx)  -  Feb 7, 2005
Barr has also gained approval for its generic version of Bristol-Myers Squibb's Videx EC Delayed-release Capsules, 200, 250, and 400 mg. ... Free with registration - Drug Topics - AccessMyLibrary.com

Factiva Search  -  Jan 18, 2005
HIV Therapy; Generic version of Videx EC antiretroviral agent approved by U.S. FDA. 18 January, 2005 Virus Weekly. 2005 JAN 18 - (NewsRx.com & NewsRx.net) ... Pay-Per-View - Virus Weekly - Factiva, from Dow Jones

B-MS 1st-qtr 2005 income down 36%.(Bristol-Myers Squibb Co.)  -  May 2, 2005
...comprises Glucophage and Glucovance (both metformin), plummeting 77% to $34.0 million; and HIV therapy Videx EC (didanosine), down 66% at $10.0 million. ... $4.95 - Pharma Marketletter - ECNext

Prohibieron la venta de más de 75 productos de farmacia  -  May 14, 2008
Además, fue prohibida la venta de todos los lotes del antirretroviral usado en tratamientos para el Sida rotulado Videx Ec (Didanosina) de 400 miligramos, ... MDZol

Article: Long-Awaited Sunscreen Approved for Sale - AP Online | …  -  Jul 24, 2006
Article: FDA approves generic version of Videx EC delayed release ... HIV Treatment: ALERTS!; April 1, 2005 ; 700+ words ... ... alternative to the original ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Press Release: Mylan Launches First Generic Version of Antihypertensiv...  -  Jul 28, 2008
Article: FDA approves generic version of Videx EC delayed ... HIV Treatment: ALERTS!; April 1, 2005 ; 700+ words ... ... In December 2004, the FDA approved ... Pay-Per-View - PR Newswire - HighBeam Research

Manglende virologisk respons hos HIV-infiserte behandlet med …  -  Jul 5, 2005
GlaxoSmithKline) og didanosin (Videx EC, Bristol-Myers Squibb) én gang daglig. Mekanismen som ligger bak den manglende responsen er ikke kjent. ... Statens legemiddelverk

Article: FDA Approves Generic Version of Pain Patch - AP Online | …  -  Feb 1, 2005
Article: FDA approves generic version of Videx EC delayed ... HIV Treatment: ALERTS!; April 1, 2005 ; 700+ words ...In December 2004, the FDA approved a ... Pay-Per-View - AP Online - HighBeam Research

Article: FDA Tentatively OKs Generic AIDS Drugs - AP Online |...  -  Jun 21, 2005
Article: FDA approves generic version of Videx EC delayed release ... HIV Treatment: ALERTS!; April 1, 2005 ; 700+ words ... ... and chalky Videx tablets. ... Pay-Per-View - AP Online - HighBeam Research

Article: US pharmaceuticals agency tentatively OKs generic version of...  -  Dec 21, 2005
Article: FDA approves generic version of Videx EC delayed ... HIV Treatment: ALERTS!; April 1, 2005 ; 700+ words ... ... In December 2004, the FDA approved ... Pay-Per-View - AP Worldstream - HighBeam Research

Brand Names/Synonyms:
Videx EC is also known by the following brand names and/or synonyms2'3'-DIDEOXYINOSINE; 2DI; CCRIS 805; DDI; DIDEOXYINOSINE; Ddi; Ddi, Didanosine; Didanosine; Didanosine [Usan:Ban:Inn]; Dideoxyinosine; Videx; Videx Ec; [Inn-Latin]; [Inn-Spanish]

Drug Category:
Videx EC is categorized under the following by the FDA: Anti-HIV Agents; Antimetabolites; Nucleoside and Nucleotide Reverse Transcriptase Inhibitors; ATC:J05AF02

Dosage Forms:
CAPSULE (ENTERIC-COATED); POWDER FOR SOLUTION; TABLET

Absorption:
Rapidly absorbed (bioavailability = 30-40%) with peak plasma concentrations appearing within 0.5 and 1.5 hrs.

Interactions:
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Chemical IUPAC Name:
9-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-3,9-dihydropurin-6-one





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