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VioxxThis page contains recent news articles, when available, and an overview of Vioxx but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Vioxx (when available) Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Rofecoxib is used for its anti-inflammatory, analgesic, and antipyretic activities in the management of osteoarthritis (OA) and for the treatment of dysmenorrhea or acute pain. Unlike celecoxib, Rofecoxib lacks a sulfonamide chain and does not require CYP450 enzymes for metabolism. For the treatment of osteoarthritis, acute pain in adults and menstrual pain Mechanism Of Action: Both COX-1 and COX-2 catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs and thromboxane. Rofecoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, important for the mediation of inflammation and pain. Unlike non-selective NSAIDs, Rofecoxib does not inhibit platelet aggregation. News Articles on Rofecoxib On Bloggingheads With Michael Specter - 14 Nov 2009 ...and we got in depth into issues like Vioxx, genetically modified foods, personalized medicine, synthetic biology, alternative medicine, and much more. ... Discover Magazine The Sharp Sword of Rationality - 14 Nov 2009 It is partly a reaction to Big Pharma's blunders and PR missteps, from Vioxx to illegal marketing ploys, which have encouraged a distrust of experts. ... Institute for Ethics and Emerging Technologies People, pigs aren't the only potential victims, but there's an upside - 14 Nov 2009 ...(Merck & Co. shares were battered after the arthritis drug Vioxx had to be pulled from shelves over heart attack concerns.) But the problem with investing ... Winnipeg Free Press Smart Rx: Drugs that work and won't break the bank - Nov 4, 2009 Perhaps the classic example of a much-hyped drug that turned out to be unsafe is Merck's painkiller Vioxx, which was pulled from the market in 2004 because ... The Associated Press Merck CEO mulls successor after merger - Nov 10, 2009 ...age of 65 in March 2011, has led Merck since Ray Gilmartin stepped down in 2005 in the wake of the withdrawal of blockbuster arthritis drug Vioxx. ... Reuters Firing Bullets of Data at Cozy Anti-Science - Nov 4, 2009 An opening chapter about the anti-inflammatory drug Vioxx describes the mess that resulted from efforts by Merck, the manufacturer of Vioxx, to obscure the ... New York Times Feds side with investors in Vioxx suit - Nov 2, 2009 The lawsuits allege Merck deliberately misrepresented the safety of Vioxx, taken off the market in 2004 over concerns it more than doubled risks of heart ... United Press International Obama backs investors' rights in Merck case - Oct 27, 2009 Investors suing Merck over Vioxx got a boost from the White House yesterday. In an amicus curiae brief filed with the Supreme Court, ... FiercePharma Unhealthy Denialism or Healthy Skepticism? Only the Specter Knows - Nov 12, 2009 But the chapters on the "irrational" response to Vioxx, hysteria around vaccines, the rise of the organic food fetish and natural supplement worship, ... The SunBreak (blog) Testing method has Cellumen poised for growth - Nov 13, 2009 Diabetes drug Rezulin was taken off the market in 2000 because of liver damage, which also was a side effect of the pain reliever Vioxx, pulled from the ... Pittsburgh Business Times Warn before habits are formed - Nov 12, 2009 Let's start with the recent example of a major safety warning: Vioxx, a non-steroidal anti-inflammatory drug developed by Merck was approved as safe and ... mydigitalfc.com Drugmakers hopeful of better FDA climate - Nov 13, 2009 Agency officials were stung by the 2004 withdrawal of Merck's arthritis pill Vioxx over heart risks and criticism from lawmakers for the handling of serious ... Reuters Musings on the intersection of science, medicine, and culture - Nov 12, 2009 A reader recently pointed to the Vioxx controversy, and although I'm not in complete agreement as to the relative harm of Vioxx, the example is a good one. ... ScienceBlogs (blog) Feared science - Nov 12, 2009 In one chapter, Specter revisits the case of Vioxx, an anti-inflammatory drug that hit the market in 1999 and was pulled five years later after evidence ... National Next to-do on Merck chief's list: Find new CEO - Nov 11, 2009 As you know, Frazier won kudos as general counsel for his legal strategy on Vioxx, the withdrawn drug that drew many thousands of lawsuits. ... FiercePharma What researchers don't want you to know about their clinical trials - Oct 26, 2009 Ioannidis singled out the cases of Vioxx, a painkiller that was withdrawn from the market because it doubled the risk of heart attack and stroke, ... Los Angeles Times Merck in a post-blockbuster world - Oct 20, 2009 NEW YORK (Fortune) -- When Richard Clark was named CEO and president of Merck in 2005, the drug behemoth was reeling in the wake of the Vioxx scandal, ... CNNMoney.com Prescription drugs that work and won't break the bank - Nov 7, 2009 Perhaps the classic example of a much-hyped drug that turned out to be unsafe is Merck's painkiller Vioxx, which was pulled from the market in 2004 because ... Abilene Reporter-News BioMarin to buy Huxley in $58M deal; ZymoGenetics scores $70M milestone; - Oct 27, 2009 Report > Investors suing Merck over Vioxx got a boost from the White House yesterday. In an amicus curiae brief filed with the Supreme Court, ... FierceBiotech Correction: Reading Pfizer's Pulse - Q3 Earnings Preview - Oct 20, 2009 It would also help offset dwindling sales of Celebrex, which has been impacted severely following the recall of the similar-acting Vioxx. ... RTT News Law Professor Files Supreme Court Amicus Brief - Nov 13, 2009 ...information about the risks of Vioxx before pulling the pain reliever from the market due to increased risks of heart attack, stroke and death. ... Rockbridge Weekly A Comprehensive Program for the Osteoporotic Patient - Oct 30, 2009 It hasn't been that long since the arthritis drug Vioxx was taken off the shelves for producing adverse side effects. ... Dynamic Chiropractic Renowned cardiovascular researcher receives Taylor Prize - Nov 2, 2009 By Communications Staff He was the first to predict the popular anti-inflammatory drug, Vioxx would increase the risk of strokes and heart attacks, ... Western News Michael S. Burg Appointed as Co-Lead Counsel in the Yasmin/Yaz Multidistrict ... - Nov 13, 2009 ...as a member of the State-Federal Liaison Committee for the Vioxx Multidistrict Litigation in the Eastern District of Louisiana, and as Co-Lead Counsel ... PR Newswire (press release) Day Two in DC: Can we police everything online? - Nov 13, 2009 But, Heartbeat Digital's Drummy wondered, what if Merck had been monitoring for adverse events with Vioxx? “How much would they have saved in terms of ... Medical Marketing and Media ARRA Funding Opportunity for Programs to Improve Rx Safety and Cut Costs - Nov 5, 2009 As The Prescription Project reports, $209 million was spent marketing the pain-killer Vioxx. This drove up utilization even though Vioxx was not clinically ... Progressive States Network (blog) Some pharmaceutical companies manufacture their own praise - Oct 24, 2009 For example, an Annals of Internal Medicine ghostwritten paper on a Merck-sponsored painkiller Vioxx clinical trial did not disclose the deaths of several ... Fort Worth Star Telegram Administration Files Amicus Brief in Shareholder Suit Against Merck - Nov 3, 2009 The brief filed by Solicitor General Elena Kagan supports the shareholders' assertion that they did not file the Vioxx (rofecoxib) lawsuit too late, ... FDA news (subscription) Shurtleff announces Zyprexa settlement - Nov 11, 2009 The firm has donated $58000 to Shurtleff and hired his daughter to work as a paralegal on Zyprexa and Vioxx cases. Shurtleff's daughter only worked for the ... Legal News Line Drug company targets critical doctors - Oct 28, 2009 According to court evidence, major drug company Merck attempted to silence critics of Vioxx with a compiled "hit list" of doctors. Drug giant Merck compiled ... The Edinburgh Journal What NSAIDs Do to Your Kidneys - Oct 26, 2009 Two others, Vioxx and Bextra, were taken off the market after they caused an unacceptable increase in cardiovascular illness and death. ... EmpowHer (blog) Illinois Hospital Association's Maryjane Wurth prepares member hospitals for ... - Nov 11, 2009 Industry watchers will recall his firm's 2005 legal victory over Merck & Co. in the Vioxx pain pill case. Although the whopping $250 million judgment in ... Chicago Tribune Canada Supreme Court Refuses Hearing on Vioxx Appeals - Oct 22, 2009 Oct. 22 (Bloomberg) -- Merck & Co. lost a bid in the Canadian Supreme Court to put a Vioxx lawsuit on hold in Ontario, while it won a ... Bloomberg Goldman Sach's Forms 'Banker's Battalion' from it's own employees. - Nov 9, 2009 Merck CEO Dick Clark was so pleased at being able to unload millions of Capsules of Vioxx in the previously successful Iraqi Campaign, that moving on to ... Motley Fool Foggy-Headed With Little Chance of Clearing - Oct 19, 2009 This was infamously demonstrated in the case of Vioxx, where initial data indicating increased risk of heart attack and stroke were downplayed by the ... Dynamic Chiropractic FDA hires consumer advocate - Oct 19, 2009 Lurie played a role in raising early alarms about several commercial drugs -- such as Pfizer's Bextra, GSK's Avandia, and Merck's Vioxx -- and in voicing ... Scientist MCM Services Group Improves Operations with Contactual's SaaS-based Contact ... - Nov 11, 2009 The company has created and run many famous campaigns, including the legal advertising campaigns in the Vioxx and Fen-Phen mass torts. ... TMCnet Unintended Acceleration Puts Toyota, Lexus Brands on Unfamiliar Ground - Oct 30, 2009 Inc. earlier this decade over its Vioxx drug. Merck pulled the drug from the market in 2005 after studies revealed it increased the risk of heart attack in ... Ward's Auto (subscription) Pharmacovigilance Report and Analysis Present Challenges and Future Goals By ... - Nov 5, 2009 Drug safety issues, such as those raised by Vioxx earlier this decade, have led to increased risk-averseness by regulators, with greater post-marketing ... PRMinds (press release) Am Law 200 Lawyers Love Christie; Corzine...Not As Much - Oct 29, 2009 Seeger Weiss, known for its litigation battles with Merck over the controversial anti-inflammatory drug Vioxx, gave $6600 to Corzine so far this year. ... The American Lawyer Winners and Losers in the House Bill - Nov 11, 2009 Just avoiding Vioxx would have had a larger impact. • Section 2587 calls for a report on neglected parasitical diseases (including Chagas). ... GoozNew (blog) Merck Announces Third-Quarter 2009 Financial Results - Oct 22, 2009 Also, includes the impact of reserving an additional $40 million solely for future legal defense costs for VIOXX litigation in the first nine months of 2009 ... Reuters Vt. testimony sharply divided on free drug samples - Oct 27, 2009 ..."Among adults two of the most sampled drugs in 2002 were Vioxx and Celebrex, obviously found within a year or two to have very serious and lethal heart ... The Associated Press Childhood vaccines, autism and the dangers of group think - Nov 4, 2009 Pharmaceutical companies, with colossal missteps like the dangerous medication Vioxx, have earned suspicions about their motivations. ... Los Angeles Times NIH declares H1N1 vaccine safe: Now the ROTS( Rest Of The Story) - Nov 3, 2009 Gardasil is manufactured by Merck who is just coming off a massive liability paying out huge sums of money with regard to their pulled drug, Vioxx. ... Examiner.com Let hospitals hire doctors - Nov 2, 2009 Medications such as Vioxx, Celebrex, Cylert, Halcion, and Clioquinol are just a few of the examples of treatments that have caused severe illnesses - even ... San Bernardino Sun Local woman feels effects of Pfizer lawsuit - Oct 30, 2009 Some of those drugs included Bextra, Vioxx, Celebrex, Effexor XR and Lyrica. Part of the settlement – $1 billion – will go to health care programs to ... Siskiyou Daily News Fitch Downgrades Merck and Upgrades Schering-Plough to 'A+' Following Merger ... - Nov 4, 2009 30, 2009 as operating cash flow of $2.13 billion at Merck, driven lower by $1.39 billion of payments into the Vioxx settlement and a $660 million tax ... Earthtimes (press release) Consumers keeping drug costs in check - Nov 7, 2009 ...take as many precautions as possible, some approved drugs later are found to cause problems — as in the famous cases of thalidomide and Vioxx. ... Clovis News Journal The Food-Pharma-Government Coalition Brings Fear Mongering and Death - Oct 21, 2009 The Vioxx scandal was a glaring example of this in action. Even after Merck, the makers of Vioxx, pulled it from shelves as being dangerously deadly, ... Natural News.com (registration) Merck Prevails in Second Vioxx Case on Heart Attack - Nov 4, 2005 By ALEX BERENSON. ATLANTIC CITY, Nov. 3 - The drug giant Merck won decisively Thursday in the second Vioxx-related personal injury case to go to trial, ... New York Times Vioxx Jury Splits in Suits by 2 Heart Patients - Apr 6, 2006 By Brooke A. Masters. A New Jersey jury ordered Merck & Co. yesterday to pay $4.5 million in the case of a man who blamed the firm's Vioxx painkiller for ... Washington Post Reports: Data on Vioxx was misused - Apr 15, 2008 By Steve Sternberg, USA TODAY. Corporate and government documents from Vioxx lawsuits indicate that the drug's maker, Merck & Co., apparently downplayed ... USA Today Analysts See Merck Victory in Vioxx Settlement - Nov 10, 2007 By ALEX BERENSON. For the drug maker Merck to pay almost $5 billion to settle lawsuits from people who contended that the painkiller Vioxx caused their ... New York Times Texas jury awards widow $253.4M in Vioxx case. - Aug 20, 2005 Aug. 20--ANGLETON, Texas -- Jurors Friday held drug giant Merck & Co. liable for the heart-related death of a 59-year-old marathon runner who took its ... Free with registration - Chicago Tribune - AccessMyLibrary.com Vioxx Anxiety Rises - Aug 17, 2006 Merck was hit today with a one-two punch in two separate court decisions relating to its withdrawn pain pill Vioxx. For the first time, Merck (nyse: MRK ... Forbes Merck Floats Vioxx Re-Stock - Feb 18, 2005 By Melissa Davis. The company may reverse the biggest drug recall in history. In a surprising announcement late Thursday, a Merck executive hinted that the ... TheStreet.com - TheStreet.com (subscription) Vioxx man awarded $9m after heart attack - Apr 11, 2006 By Rhys Blakely, and agencies in New Jersey. An American jury has awarded $9 million (£5m) in punitive damages to a man who blamed his heart attack on Vioxx ... Times Online Vioxx Jury Awards $47.5M to Idaho Couple - Mar 12, 2007 By LINDA A. JOHNSON, AP Business Writer. Merck & Co.'s painkiller Vioxx contributed to an Idaho postal worker's heart attack, a jury in Atlantic City ruled ... FOXNews New England Journal of Medicine questions Merck Vioxx study. - Dec 9, 2005 Dec. 9--In an unusual move, the New England Journal of Medicine Thursday questioned the integrity of a key study Merck & Co. has used to defend its troubled ... Free with registration - Chicago Tribune - AccessMyLibrary.com Merck says Vioxx claimants will soon get checks - Jul 17, 2008 By Ransdell Pierson. NEW YORK (Reuters) - Merck & Co (MRK.N) said on Thursday that more than 97 percent of eligible US claimants had elected to participate ... Reuters Merck shares jump on Vioxx rulings, raised forecast - MarketWatch - Apr 13, 2007 By Val Brickates Kennedy, MarketWatch. BOSTON (MarketWatch) -- Shares of Merck & Co. jumped Friday, playing off a greatly improved 2007 earnings forecast as ... MarketWatch Merck may pull back from Vioxx fight and settle some cases - Aug 28, 2005 By Sylvia Pfeifer. Merck, the US pharmaceuticals giant, is considering settling some lawsuits from patients who allege they were harmed after taking its ... Telegraph.co.uk 3-3 Vioxx tie shows pattern for Merck, plaintiffs - Apr 24, 2006 AP. NEW YORK -- After millions of dollars in expenses and hundreds of hours of court time in six separate trials, neither Merck nor plaintiff attorneys have ... News & Observer Vioxx risk lingers at least 1 year after using drug - Oct 13, 2008 TRENTON, NJ - A doubled risk of heart attack, stroke and death persisted at least a year after people stopped taking withdrawn painkiller Vioxx, ... msnbc.com Jurors Side With Merck in Vioxx Trial - Mar 27, 2007 By JIM SUHR, AP Business Writer. A state jury Tuesday sided with Vioxx maker Merck & Co. over claims that its once-blockbuster painkiller caused the 2003 ... FOXNews Jury finds Merck liable for Vioxx death - Aug 19, 2005 By Val Brickates Kennedy, MarketWatch. BOSTON (MarketWatch) -- A Texas jury found Merck & Co. liable Friday in the sudden cardiac death of a man who had ... MarketWatch Victory for Merck in Louisiana Vioxx Case - Feb 18, 2006 Phil Beck, a lawyer for Merck, said he believed the verdict indicated that the jury found "that the Merck scientists lived up to their legal and ethical ... Pay-Per-View - Los Angeles Times - ProQuest Archiver Merck agrees to $58M settlement over Vioxx ad claims - May 20, 2008 AP Writer / May 20, 2008. HARRISBURG, Pa.—Drug-maker Merck must allow the Food and Drug Administration to review future prescription-drug television ad ... Boston Globe Up to 140,000 heart attacks linked to Vioxx - Jan 25, 2005 Up to 140000 extra heart attacks may have been caused in the US by the recently withdrawn drug Vioxx since its launch in 1999, suggests a new study. ... New Scientist US panel rejects Merck's Vioxx successor - Apr 12, 2007 By Lisa Richwine. GAITHERSBURG, Md., April 12 (Reuters) - Merck & Co Inc.'s (MRK.N) successor to the recalled pain reliever Vioxx should not be approved, ... Reuters Vindicating Vioxx - May 31, 2008 Texas and New Jersey may have different political cultures, but appeals courts in both states this week delivered a one-two punch to the liability suits ... Wall Street Journal Vioxx court case ends in mistrial - Dec 12, 2005 A US judge has declared a mistrial in the first federal lawsuit against drugs giant Merck and its Vioxx painkiller. The move came after a jury in Houston ... BBC News Merck Wins Vioxx Case - Jul 13, 2006 By Robert Steyer. A New Jersey state court jury has rejected a woman's claim that Merck's (MRK) arthritis drug Vioxx caused her heart attack two years ago. ... TheStreet.com - TheStreet.com (subscription) Vioxx Damages Award Tossed - Aug 30, 2006 By TSC Staff 08/30/06 - 01:53 PM EDT. A judge has thrown out a $50 million compensatory-damages award imposed against Merck (MRK Quote) in a recent Vioxx ... TheStreet.com - TheStreet.com (subscription) New York State, New York City sue Merck over Vioxx - Sep 17, 2007 By Emily Chasan. NEW YORK, Sept 17 (Reuters) - The state and city of New York on Monday filed suit against Merck & Co Inc (MRK.N), claiming the drugmaker ... Reuters Vioxx maker says a return is possible - Feb 17, 2005 By Rita Rubin, USA TODAY. GAITHERSBURG, Md. — Given new information about the risks of other arthritis drugs, Vioxx could be returned to the market, ... USA Today Texas wins $4 million in Vioxx settlement from Merck - May 21, 2008 Texas and 28 other states will share a $58 million payment from pharmaceutical giant Merck & Co., which resolves longstanding claims that the company ... Bizjournals.com Jury to begin deliberations in California Vioxx trial - Aug 2, 2006 By ALEX VEIGA, AP Business Writer. The jury in California's first trial over the painkiller Vioxx was scheduled to begin deliberations Wednesday to decide ... San Francisco Chronicle FDA Says No to Vioxx Successor - Apr 27, 2007 By EJ Mundell. FRIDAY, April 27 (HealthDay News) -- The US Food and Drug Administration on Friday turned down Merck & Co.'s request to market Arcoxia, ... Washington Post Appeals court overturns $7.75 mln Vioxx verdict - May 14, 2008 NEW YORK (Reuters) - An appeals court in Texas overturned a $7.75 million verdict against Merck & Co (MRK.N) involving its withdrawn pain drug Vioxx on ... Reuters UK Vioxx death toll may hit 60,000 - Aug 23, 2005 BEIJING, Aug. 23 -- About 60000 people worldwide are estimated to have died after using the painkiller Vioxx manufactured by Merck, the third-largest drug ... æ–°å?Žç½‘ Clark's Merck Loses Sixth Vioxx Trial - Apr 21, 2006 In Rio Grande City, a jury found that Merck (nyse: MRK - news - people ) was responsible for the death of a one-time Vioxx user. ... Forbes Merck wins appeal on first Vioxx case - May 29, 2008 By Bill Berkrot. NEW YORK, May 29 (Reuters) - A Texas appeals court on Thursday reversed a $26.1 million decision against Merck & Co (MRK. ... Reuters India Mixed Verdicts for Merck in Vioxx Cases - Mar 3, 2007 By ANDREW POLLACK. A New Jersey state jury ruled that Merck had failed to provide adequate warning about the risks of its Vioxx painkiller in one of two ... New York Times Vioxx aggressively marketed despite concerns - May 5, 2005 Manuel Balce Ceneta / AP. WASHINGTON - Merck & Co. sales personnel, using projects code-named “Offenseâ€? and “XXceleration,â€? took extensive measures to boost ... msnbc.com Merck Vioxx Study Disguised Marketing as Science - Aug 19, 2008 By Brandon Keim. A study that touted the benefits of Vioxx, a painkiller that killed thousands, wasn't science: it was marketing propaganda. ... Wired News FDA rejects Vioxx-like painkiller - Apr 28, 2007 By Diedtra Henderson, Globe Staff | April 28, 2007. WASHINGTON -- The Food and Drug Administration yesterday rejected Merck & Co.'s new Vioxx-like ... Boston Globe Vioxx Trial Back in Action in NJ - Mar 6, 2006 ATLANTIC CITY, NJ — Merck & Co. (MRK) knew its painkiller Vioxx significantly increased the risk of heart attack but worked to hide the evidence from ... FOXNews Second Vioxx trial under way in New Jersey - Sep 14, 2005 ATLANTIC CITY, NJ - A product liability trial focused on whether the painkiller Vioxx caused a man's heart attack started Wednesday, with his lawyer telling ... msnbc.com Jury Clears Merck In 11th Vioxx Trial - Nov 16, 2006 By Janet McConnaughey. AP. A federal jury yesterday cleared Merck & Co. in the July 2003 heart attack suffered by a Utah bank credit manager who had taken ... Washington Post Merck Sued by State of Florida Over Vioxx Marketing Claims - Sep 30, 2008 By Andrew Pollack. Sept. 30 (Bloomberg) -- Merck & Co. was sued by the state of Florida today over the drugmaker's promotion of its now-withdrawn painkiller ... Bloomberg Merck wins reversal of Vioxx class-action status - Sep 6, 2007 By Ransdell Pierson. NEW YORK (Reuters) - Merck & Co Inc said on Thursday the New Jersey Supreme Court has reversed a lower court ruling that granted ... Reuters India Study: Vioxx danger to heart, kidneys; Potentially fatal side effects... - Sep 13, 2006 By Michelle Fay Cortez and Angela Zimm. Merck & Co. Inc.'s withdrawn Vioxx pain reliever raised heart and kidney risks, in some cases within a month of ... Pay-Per-View - Philadelphia Inquirer - Factiva, from Dow Jones Clark's Merck Faces New Vioxx Trial In 2 Weeks - Aug 30, 2005 London - A request from embattled drug maker Merck to delay the next trial over its pulled painkiller Vioxx was nixed Monday by a New Jersey judge. ... Forbes Amid $4.5B Vioxx deal, more Merck suits - Mar 7, 2008 TRENTON, NJ (AP) - Merck & Co. is on the verge of settling most serious personal injury lawsuits over Vioxx, but the drugmaker still faces substantial ... Forbes Merck says new drug is safer than Vioxx - Nov. 13, 2006 - Nov 13, 2006 Arthritis drug Arcoxia has lower heart attack risk, company says at American Heart Association meeting. By Aaron Smith, CNNMoney.com staff writer ... CNNMoney.com Ex-Merck scientist's views on Vioxx changed.(Dr. Edward Scolnick) - Dec 6, 2005 Dec. 6--The former top scientist at Merck testified Monday that he initially concluded an internal study of Vioxx linked the drug to an increase in heart ... Free with registration - Houston Chronicle - AccessMyLibrary.com Vioxx class-action rejected Attorney says he will now pursue separate... - Sep 7, 2007 By LINDA JOHNSON .AP . Trenton, NJ - New Jersey's Su preme Court on Thursday rejected a class-action lawsuit against Merck Co. over its withdrawn painkiller ... Milwaukee Journal Sentinel - Google News Archive 93% have filed for Vioxx settlement, Merck says - Mar 3, 2008 Merck & Co. Inc. said Monday it continues to make progress on its $4.85 billion Vioxx settlement agreement. According to the pharmaceutical company, ... Bizjournals.com Merck Stands by Vioxx Study Data - Feb 23, 2006 There's renewed controversy over a scientific paper published five years ago on the safety of the painkiller Vioxx. The dispute centers on whether drugmaker ... NPR Merck Lawyer Impugns Story in Vioxx Suit - Nov 1, 2005 By ALEX BERENSON. ATLANTIC CITY, Oct. 31 - A Merck lawyer questioned the plaintiff's credibility in a closing argument Monday at the Vioxx personal injury ... New York Times Plaintiffs Find Payday Elusive in Vioxx Cases - Aug 21, 2007 By ALEX BERENSON. KEENE, Tex. — In Carol Ernst's eyes, two years ago she won a measure of justice. Carol Ernst is one of many to sue Merck, arguing that ... New York Times Witness asked about Vioxx, heart studies - Jul 20, 2005 ANGLETON, Texas (AP) — Merck didn't do any significant studies on whether Vioxx could cause heart attacks or other serious cardiovascular problems before ... USA Today Jury Trial Begins in Texas Vioxx Case; Plaintiff's lawyer says he'll... - Jul 15, 2005 ...[Vioxx] was crucial to Merck, [Mark Lanier] argued, because patents on other lucrative drugs ran out in 2000 and 2001 and "if Vioxx doesn't fill up the ATM ... Pay-Per-View - Los Angeles Times - ProQuest Archiver Lawyer Presses Expert Witness To Apologize During Vioxx Trial - Sep 21, 2005 By Paul Davies. ATLANTIC CITY, NJ -- A lawyer representing Merck & Co. in the second Vioxx trial pressed an expert witness for the plaintiff to apologize ... Pay-Per-View - Wall Street Journal - Factiva, from Dow Jones Return of Vioxx would be unusual, not unprecedented - Feb 21, 2005 By Julie Schmit, USA TODAY. If Merck puts painkiller Vioxx back on the market after removing it because of safety concerns, it would be an unusual but not ... USA Today Merck to slash jobs in wake of Vioxx debacle - Nov 27, 2005 By Sylvia Pfeifer. Merck, the US pharmaceuticals giant, is poised to announce a major restructuring plan that could lead to large-scale job cuts and plant ... Telegraph.co.uk Vioxx class action claim refused - Nov 22, 2006 Thousands of personal injury lawsuits involving the painkiller Vioxx cannot be pooled together into a class action, a US federal judge has ruled. ... BBC News Expert testifies Vioxx can cause deadly clots. - Nov 30, 2005 Nov. 30--A nationally known pharmacology expert testified Tuesday that the prescription painkiller Vioxx can cause blood clots like the one that led to the ... Free with registration - Houston Chronicle - AccessMyLibrary.com Challenge Filed To $4.85B Vioxx Settlement - Jan 4, 2008 Merck & Co. will pay $4.85 billion to settle thousands of lawsuits filed by people or family members who claimed the drug Vioxx proved fatal or injured its ... CBS News First Vioxx trial gets under way in Texas - Jul 14, 2005 ANGLETON, Texas - Merck & Co. traded its mission of healing and treating sickness for relentless marketing and pursuit of profits, a plaintiff's lawyer in ... msnbc.com Vioxx producer to cut 7,000 jobs - Nov 28, 2005 The manufacturer of controversial drug Vioxx has revealed plans to cut 7000 jobs on the eve of the first federal trial relating to the drug's use. ... BBC News Heart expert faults Merck in Vioxx trial - Sep 18, 2005 Fighting back tears, a heart expert told jurors that Vioxx manufacturer Merck & Co. ignored evidence the painkiller posed safety risks before it hit the ... Taipei Times - Taipei Times FDA official says agency acted too slowly on Vioxx - Mar 2, 2005 ...(03-02) 04:00 PDT Washington -- After the Food and Drug Administration insisted for months that it had done nothing wrong in its oversight of the withdrawn ... San Francisco Chronicle Vioxx may go back on sale after scraping past FDA panel - Feb 24, 2005 Advisers to the US Food and Drug Administration (FDA) have voted, by a narrow margin, that it should not ban Vioxx — the painkiller withdrawn by drug-maker ... Nature.com Study says Vioxx danger begins earlier than stated - Jul 25, 2007 By Bill Berkrot. NEW YORK (Reuters) - The increased heart risk from Vioxx, Merck & Co's withdrawn arthritis medicine, begins much earlier than after 18 ... Reuters UK Deadlocked jury will resume talks in Vioxx trial - Dec 11, 2005 By Diedtra Henderson, Globe Staff | December 11, 2005. WASHINGTON -- Five of nine jurors in Texas agreed that Vioxx played a role in the death of a Florida ... Boston Globe Jury sides with Merck in federal Vioxx trial . - Sep 27, 2006 ...trade association formerly the American Electronics Association. This year's growth almost doubled the total for the first half of 2005 and brought the ... St. Petersburg Times - Google News Archive Cardiologist says Vioxx still a risk after stopping - May 13, 2006 By Bill Berkrot. NEW YORK (Reuters) - A leading cardiologist on Friday disputed Merck & Co's interpretation on the safety of patients once they stop taking ... Malaysia Star Medical Journal Publishes Correction on Vioxx Study - Jun 27, 2006 ...by Snigdha Prakash. The New England Journal of Medicine has published a correction to a Vioxx study that has figured prominently in Merck's legal defense of ... NPR Scientist: Vioxx Harmed 139,000 - Jan 3, 2005 WASHINGTON — The Food and Drug Administration (search) has given a whistle-blower scientist permission to publish data indicating that as many as 139000 ... FOXNews Patent application raises questions about Merck, Vioxx. - Jun 22, 2005 PHILADELPHIA _ Three years before Merck & Co. Inc. conceded its pain-reliever Vioxx had safety problems, the company tried to patent a way to reduce ... Free with registration - Philadelphia Inquirer - AccessMyLibrary.com Youth may play vital role in Vioxx case.(Merck and Company Inc.) - Aug 2, 2005 Aug. 2--ANGLETON -- Two of the jurors who will decide if Merck & Co. Inc. caused the death of 59-year-old Robert Ernst are only 20 years old. ... Free with registration - Houston Chronicle - AccessMyLibrary.com Merck Adds to Vioxx Data - May 11, 2006 By Robert Steyer. Clinical-trial patients who discontinued taking the arthritis drug Vioxx for 12 months were at equal risk for cardiovascular injury as ... TheStreet.com - TheStreet.com (subscription) EX-CEO DENIES MERCK WITHHELD VIOXX DATA - Apr 7, 2006 The former CEO of Merck & Co. on Thursday denied a plaintiff lawyer's suggestions that the drug maker withheld information about the safety of its ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver Merck wins second Vioxx verdict in one week - Dec. 15, 2006 - Dec 15, 2006 Merck, vowing to fight cases one-by-one, is victorious in Alabama Vioxx verdict, its second win this week. By Aaron Smith, CNNMoney.com staff writer ... CNNMoney.com Vioxx verdict undermines early gains - Aug 20, 2005 By Christopher Wang. AP. NEW YORK — Stocks ended an uneasy week mostly higher yesterday as a jury verdict against Merck over its painkiller Vioxx erased ... Seattle Times Merck Sees Successor to Vioxx - Aug 24, 2006 By ALEX BERENSON. Setting the stage for a scientific and regulatory battle, Merck said yesterday that a potential successor to its painkiller Vioxx had ... New York Times Merck counts the cost of Vioxx withdrawal - Jan 26, 2005 By Stephen Foley. The pharmaceutical giant Merck has set aside $604m (£324m) just to pay lawyers' bills as it prepares to deal with legal actions from at ... Independent Long-term study confirms Vioxx heart risks - Oct 13, 2008 By Julie Steenhuysen. CHICAGO, Oct 13 (Reuters) - A long-term analysis of people who took the arthritis drug Vioxx confirms it doubles the risk of strokes ... Reuters Merck wins 7th Vioxx suit ; Jury: Painkiller not cause of heart attack - Dec 14, 2006 Merck has won seven cases and lost four since it began going to trial in 2005. An eighth Merck victory was overturned. [Anthony Wayne Dedrick]'s is one of ... Pay-Per-View - Chicago Tribune - ProQuest Archiver Merck: Studies showed Vioxx unrelated to possible heart trouble - Oct 6, 2005 By Bonnie Pfister. AP. ATLANTIC CITY, NJ – Merck & Co. opened its defense Thursday in the second product-liability trial over its arthritis medicine, ... San Diego Union - Tribune - San Diego Union Tribune Jury Selection In First Vioxx Case - Jul 11, 2005 By Jill Preschel. (AP) Merck & Co. has vowed to defend itself against more than 3800 pending state and federal lawsuits alleging it knew its popular ... CBS News Merck wins first federal Vioxx trial - Feb 17, 2006 By Gabriel Madway, MarketWatch. SAN FRANCISCO (MarketWatch) -- Merck & Co. said late Friday that a federal court jury in New Orleans has rejected a claim ... MarketWatch Lawmakers Begin Pondering Post-Vioxx Reforms - Mar 1, 2005 By Todd Zwillich. March 1, 2005 -- A top FDA official says the agency took too long to add safety warnings to the now-recalled pain killer Vioxx. ... WebMD Merck faces tough road after Vioxx, Fosamax setbacks - Jan. 28, 2005 - Jan 28, 2005 By Aaron Smith, CNN/Money staff writer. NEW YORK (CNN/Money) - Merck & Co.'s latest double dose of bad news is likely to put a big dent in its earnings and ... CNN International Is Avandia set to be Glaxo's Vioxx? - Jun 6, 2007 Sales of Avandia, GSK's blockbuster diabetes pill, have been in sharp decline since a study concluded that it increased the risk of heart problems. ... Independent Study finds heart disease among thousands of patients taking Vioxx. - Jan 24, 2005 CHICAGO _ Two months after federal drug officials sought to delay release of a study linking the painkiller Vioxx to heart attack, the results were ... Free with registration - Chicago Tribune - AccessMyLibrary.com For Former Vioxx Users, Celebrex May Be an Option - Sep 12, 2006 By RYAN STANTON, MD, ABC News Medical Unit. The painkiller Celebrex may be safe for some patients who suffer from chronic bone and joint pain, ... ABC News Ex-Merck exec, Vioxx plaintiff lawyer spar - Aug 5, 2005 By KRISTEN HAYS. AP. ANGLETON, Texas (AP) — Merck & Co.'s former top scientist in charge of Vioxx studies bristled Friday when pressed about whether the ... MLive.com Vioxx may increase risk of heart attack even faster - May 3, 2006 Vioxx, the popular painkiller pulled from drugstores two years ago in the largest drug recall ever, increases the risk of heart attacks far faster than ... Canada.com Jury chosen in Atlantic City for next Vioxx trial - Jun 2, 2006 By Linda A. Johnson. AP. TRENTON, NJ – A jury of five women and five men was selected Friday in Atlantic City for the seventh trial against drug maker Merck ... San Diego Union - Tribune - San Diego Union Tribune Opponents ready their arguments in first Vioxx trial - Jun 27, 2005 By Kristen Hays. AP. HOUSTON – For more than eight months, Vioxx eased the pain and stiffness in Robert Ernst's hands. But eight days after Ernst, ... San Diego Union - Tribune - San Diego Union Tribune … ARTHRITIS PATIENTS' POST-VIOXX CONFUSION ABOUT THESE … - Jan 24, 2005 When safety concerns led to removal of the popular arthritis drug Vioxx from ... Early studies hinted that Vioxx might be associated with increased risk of ... $2.95 - Charlotte Observer - NewsBank Merck denies news report on health risks in early Vioxx use - May.... - May 18, 2006 By Aaron Smith, CNNMoney.com staff writer. NEW YORK (CNNMoney.com) - Merck is denying news reports that suggest new data from the drug maker indicates Vioxx ... CNN Merck wins reversal of Vioxx award - May 15, 2008 AP. Trenton, NJ —- A Texas appeals court on Wednesday overturned a multimillion-dollar verdict against Merck & Co. in a case involving its withdrawn ... Atlanta Journal Constitution Vioxx Judge Nixes Key Merck Witness Testimony - Oct 7, 2005 ATLANTIC CITY, NJ — The judge in the second Vioxx (search) product liability trial delivered a stunning blow to Merck & Co. (MRK) Friday when she struck the ... FOXNews Legal fight over Vioxx now shifts to Atlantic City. - Sep 11, 2005 Sep. 11--Starting Monday, lawyers, Wall Street analysts and former users of Vioxx will turn their eyes to a state court in Atlantic City. ... Free with registration - The Record - AccessMyLibrary.com Major Vioxx Study Corrected - Jun 26, 2006 By Robert Steyer. The New England Journal of Medicine published a correction of a major research article, adding more fuel to the fiery debate about Vioxx, ... TheStreet.com - TheStreet.com (subscription) Brand Names/Synonyms: Vioxx is also known by the following brand names and/or synonymsCCRIS 8967; CHEMBANK1837; MK 0966; MK 0996; MK 966; MK 996; Rofecoxib; Vioxx Drug Category: Vioxx is categorized under the following by the FDA: Anti-inflammatory Agents; Nonsteroidal Antiinflammatory Agents (NSAIDs); ATC:M01AH02 Dosage Forms: Tablets, oral suspension Absorption: The mean oral bioavailability of VIOXX at therapeutically recommended doses of 12.5, 25, and 50 mg is approximately 93% Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: 4-(4-methylsulfonylphenyl)-3-phenyl-5H-furan-2-one |
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