Zafirlukast

This page contains recent news articles, when available, and an overview of Zafirlukast but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Zafirlukast
(when available)

Pharmacology and use:
Zafirlukast is a synthetic, selective peptide leukotriene receptor antagonist (LTRA) indicated for the prophylaxis and chronic treatment of asthma. Patients with asthma were found in one study to be 25-100 times more sensitive to the bronchoconstricting activity of inhaled LTD4 than nonasthmatic subjects. in vitro studies demonstrated that Zafirlukast antagonized the contractile activity of three leukotrienes (LTC4, LTD4 and LTE4) in conducting airway smooth muscle from laboratory animals and humans. Zafirlukast prevented intradermal LTD4-induced increases in cutaneous vascular permeability and inhibited inhaled LTD4-induced influx of eosinophils into animal lungs. For the prophylaxis and chronic treatment of asthma

Mechanism Of Action:
Zafirlukast is a selective and competitive receptor antagonist of leukotriene D4 and E4 (LTD4 and LTE4), components of slow-reacting substance of anaphylaxis (SRSA). Cysteinyl leukotriene production and receptor occupation have been correlated with the pathophysiology of asthma, including airway edema, smooth muscle constriction, and altered cellular activity associated with the inflammatory process, which contribute to the signs and symptoms of asthma.

News Articles on Zafirlukast

Orkan in den Atemwegen  -  ‎Oct 27, 2009‎
Es ist auch eine antientzündliche Therapie mit Leukotrienantagonisten (Zafirlukast, Montelukast) möglich. In der überwiegenden Anzahl der Fälle sistiert ... Pharmazeutische Zeitung online

Learn about Zafirlukast from Consumer Reports Health.  -  Jan 1, 2007
Zafirlukast is used to prevent asthma symptoms. Zafirlukast is in a class of medications called leukotriene receptor antagonists (LTRAs). ... consumerreports.org

Zafirlukast (Systemic).  -  Oct 27, 2005
Zafirlukast (za-FIR-loo-kast) is used by patients with mild-to-moderate asthma to decrease the symptoms of asthma and the number of acute asthma attacks. ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Zafirlukast Treatment in Patients with Acute Asthma  -  Oct 1, 2005
There are 2 million emergency department visits and almost 500000 hospital admissions annually in the United States because of acute asthma. ... AAFP News Now

How to take Zafirlukast from Consumer Reports Health.  -  Jan 1, 2007
...tell your doctor and pharmacist if you are allergic to zafirlukast or any other medications. tell your doctor and pharmacist what prescription and ... consumerreports.org

… of Category III A Prostatitis With Zafirlukast: a Randomized...  -  Apr 8, 2005
Summary: The cause of category III A prostatitis, chronic prostatitis/chronic male pelvic pain syndrome category A (CP/CPPS A), is uncertain. ... RedOrbit

High-dose zafirlukast in emergency department provides small benefit...  -  Apr 1, 2005
Does high-dose zafirlukast reduce the need for hospital admission in patients with an acute asthma exacerbation, and does 1 month of zafirlukast prevent ... $4.95 - Journal of Family Practice - ECNext

IN BRIEF: Zafirlukast well tolerated.(Brief article)  -  May 12, 2007
Zafirlukast is a well-tolerated drug with few associated adverse events, an English post-marketing surveillance study has concluded. ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

IN BRIEF: Zafirlukast well tolerated.(Brief article)  -  May 12, 2007
Zafirlukast is a well-tolerated drug with few associated adverse events, an English post-marketing surveillance study has concluded. $4.95 - Chemist & Druggist - ECNext

Leukotriene pathway modifiers for long-term control of asthma  -  May 15, 2007
In rare cases, zafirlukast and zileuton cause liver damage. If the liver is being affected by zafirlukast or zileuton, liver function tests will show ... MSN Health & Fitness

Intermittent Inhaled or Oral Steroids May Be Sufficient for Mild...  -  Apr 13, 2005
Compared with intermittent therapy or daily zafirlukast therapy, daily budesonide therapy ... Daily zafirlukast therapy was not significantly different from ... Medscape

Leukotriene antagonists.(Drug overview)  -  May 24, 2006
Examples of this medicine are montelukast (Singulair), zafirlukast ... Montelukast is taken once daily in the evening, whereas zafirlukast is taken twice ... $4.95 - Clinical Reference Systems - ECNext

Leukotrienes: their role in the treatment of asthma and seasonal...  -  Jan 1, 2005
Case studies have suggested zafirlukast and zileuton affect theophylline and ... Side effect of zafirlukast include headache, which was reported by 4.5 % of ... $4.95 - Pediatric Nursing - ECNext

Leukotriene antagonists.(Pediatric Advisor 2006)(Drug overview)  -  Nov 1, 2006
Zafirlukast is approved for use in children 5 years of age and older. ... Zafirlukast comes in 2 strengths (10 mg, 20 mg) and is taken twice daily, ... $4.95 - Clinical Reference Systems - ECNext

Leukotriene inhibitors in the treatment of allergy and asthma.  -  Jan 1, 2007
The leukotriene receptor antagonists include zafirlukast (Accolate) and ... Zafirlukast is approved for treatment of asthma in patients seven years or older ... Free with registration - American Family Physician - AccessMyLibrary.com

Ça m'gratouille docteur... la faute aux leucotriènes ?  -  Dec 11, 2008
Zafirlukast : pas d'effet bénéfique dans le traitement de l'urticaire chronique. ... OBJECTIF : Déterminer l'efficacité thérapeutique du Zafirlukast dans ... Allergique - Allergique (Abonnement)

Cysteinyl leukotrienes in allergic inflammation *: strategic target...  -  Apr 1, 2005
...(45) Similarly, adding montelukast or zafirlukast to ICS further increased the ... (59) Zafirlukast significantly reduced nighttime awakenings in 5- to ... Pay-Per-View - Chest - Factiva, from Dow Jones

Leukotriene antagonists.(Pediatric Advisor 2007)(Drug overview)  -  May 31, 2007
Zafirlukast is approved for use in children 5 years of age and older. ... Zafirlukast comes in 2 strengths (10 mg, 20 mg) and is taken twice daily, ... $4.95 - Clinical Reference Systems - ECNext

Leukotriene Receptor Antagonists for the Treatment of Allergic Skin …  -  Jul 1, 2008
Leukotriene receptor antagonists (montelukast and zafirlukast) do not have approval from the US Food and Drug Administration for dermatologic uses. ... AAFP News Now

Leukotriene modifiers for allergic rhinitis  -  Aug 8, 2007
Other leukotriene modifiers include zafirlukast (Accolate) and zileuton (Zyflo). ... Zafirlukast may interact with other medicines, and zileuton may cause ... WebMD

Pharmacotherapy — first-line maintenance therapy  -  Sep 13, 2005
Although the study looked at 4 doses of zafirlukast (5 mg, 10 mg, ... Zafirlukast significantly increased the change from baseline in percent predicted FEV ... CMAJ

Leukotriene inhibitors in the treatment of allergy and asthma.  -  Jan 1, 2007
The leukotriene receptor antagonists include zafirlukast (Accolate) and ... Zafirlukast is approved for treatment of asthma in patients seven years or older ... $4.95 - American Family Physician - ECNext

Daily inhaled steroids for mild asthma?  -  Jun 15, 2005
Patients were then randomized to one of three treatments: 200 mcg of budesonide (inhaler) + placebo tablets, 20 mg of zafirlukast twice daily + placebo ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Loislaw Federal District Court Opinions - RAUNIO v. HAHN (WDWis. 2-26...  -  Feb 26, 2007
To manage these ailments, he has been prescribed several medications, including Advair, zafirlukast and albuterol for his asthma and naproxen for his pain. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Intermittent steroids an option in mild asthma.(Pulmonary Medicine)  -  Jun 1, 2005
Daily zafirlukast therapy did not differ significantly from intermittent treatment in any outcome measured. Although the findings must be considered ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Asthma Drug Proven to Make Patients Worse than if taking Placebo  -  Sep 1, 2008
The asthma drug, Accolate (zafirlukast), shows benefits for the first five weeks, and then becomes ineffective. Within seven weeks, the drug becomes ... Alternative Health Journal

Is daily inhaled steroid use necessary in the treatment of mild...  -  May 24, 2005
Patients received either budesonide, 200 µg inhaled twice daily; zafirlukast (a leukotriene inhibitor), 20 mg orally twice daily; or placebo. ... CMAJ

How Should Pregnant Women Deal With Asthma?  -  May 5, 2007
...the oral drugs montelukast (Singulair) or zafirlukast (Accolate); and an injected medication, omalizumab (Xolair). Beta agonists, such as albuterol, ... Pay-Per-View - Tampa Tribune - ProQuest Archiver

Asthma medications: Know your options  -  Jun 15, 2006
Leukotriene modifiers include montelukast (Singulair) and zafirlukast (Accolate). Used in conjunction with other medications — such as inhaled ... CNN

A patient-oriented approach to the management of allergic rhinitis.(CM...  -  Sep 1, 2005
...(27) Although zafirlukast is currently indicated only for the treatment of asthma, it has been studied in clinical trials for the treatment of patients with ... $4.95 - Clinician Reviews - ECNext

ASK AN EXPERT  -  May 31, 2008
Leukotriene modifiers such as montelukast (Singulair), zafirlukast (Accolate) and zileuton (Zyflo CR). These inhaled medications work by opening airways, ... CNN International

Considering the role of NPPV, PEEP, and other interventions --...  -  Mar 1, 2007
Silverman RA, Miller CJ, Chen Y. Zafirlukast reduces relapses and treatment failures after an ... Zafirlukast Zileuton Copyright [c] 2007 CMP Media LLC. ... $4.95 - Journal of Respiratory Diseases - ECNext

Un estudio propugna menos medicación en el asma leve  -  Apr 16, 2005
...la budesonida, o el inhibidor de los leucotrienos zafirlukast. ... otros el zafirlukast y los terceros, un placebo (sustancia inactiva). ... elmundo.es

Variable presentation of temporalis hypertrophy — A case report with ...  -  Aug 12, 2006
Medication at the time of presentation included salbutamol sulphate (Ventolin), fluticasone propionate (Seretide), zafirlukast (Accolate) and budesonide ... Nature.com

Dust mite allergy  -  Nov 8, 2008
These drugs include montelukast (Singulair), zafirlukast (Accolate) and zileuton (Zyflo CR). These may be used alone or as a supplemental drug for asthma ... CNN International

Intermittent vs. Continuous Therapy for Mild Asthma  -  Aug 1, 2005
Bottom Line: Intermittent therapy, as measured by patient-oriented, clinical outcomes, is as effective as continuous therapy with oral zafirlukast or ... AAFP News Now

Possible Link between Singulair and Suicide  -  Mar 28, 2008
Singulair is a leukotriene receptor antagonist with mechanism of action similar to Accolate (zafirlukast). It has been marked in the United States for 10 ... Enews 2.0

Intermittent = continuous therapy for mild persistent asthma.(Patient...  -  Jul 1, 2005
Bottom line Intermittent therapy, as measured by the outcomes that matter, is as effective as continuous therapy with oral zafirlukast or inhaled budesonide ... Free with registration - JAAPA-Journal of the American Academy... - AccessMyLibrary.com

Pet allergy  -  Nov 22, 2008
These drugs include montelukast (Singulair), zafirlukast (Accolate) and zileuton (Zyflo CR). These may be used alone or as a supplemental drug for asthma ... CNN

Chronic urticaria.(Drug Update)  -  Jan 1, 2005
May be beneficial [Singulair] when used in combination with an antihistamine, especially in patients with urticaria accompanied by angioedema. zafirlukast ... Free with registration - Family Practice News - AccessMyLibrary.com

Do Patients with Mild Asthma Need Daily Inhaled Steroids?  -  May 26, 2005
...to receive twice-daily inhaled budesonide plus placebo tablets, twice-daily oral zafirlukast plus placebo inhaler, or twice-daily double placebo. ... Medscape

Asthma drug effectiveness dependent on genes  -  Jun 19, 2006
Other long-term control medicines include, Leukotriene modifiers (montelukast, zafirlukast, and zileuton), which are used either alone to treat mild ... DrugResearcher.com

Exercise-induced asthma  -  Nov 21, 2007
A leukotriene modifier, such as montelukast sodium (Singulair) or zafirlukast (Accolate), for effects lasting up to 24 hours. These drugs are helpful in ... CNN International

How to take Pimecrolimus Topical from Consumer Reports Health.  -  Jan 7, 2006
...nefazodone; oral contraceptives (birth control pills); other ointments, creams, or lotions; troleandomycin (TAO); and zafirlukast (Accolate). ... consumerreports.org

FACTBOX: Asthma drugs attack from several angles  -  Aug 29, 2007
Leukotriene modifiers include montelukast, sold by Merck and Co. under the brand name Singulair and zafirlukast, sold by AstraZeneca under the brand name ... Reuters

Treating asthma/avoiding SVT.(CLINICAL TWISTERS)  -  Nov 20, 2006
...modifier such as montelukast or zafirlukast (Accolate, AstraZeneca). Sustained-release theophylline is not a viable option due to T.C.'s tachycardia. ... Free with registration - Drug Topics - AccessMyLibrary.com

FDA Investigates Possible Suicide Link With Montelukast (Singulair)  -  Mar 27, 2008
Other leukotriene modifying medications include zafirlukast (Accolate), which is also a leukotriene receptor antagonist and zileuton (Zyflo and Zyflo CR), ... MedPage Today

Dr. Mitchell Glass Joins TOPIGEN's Scientific Advisory Board  -  Apr 2, 2006
...including ACCOLATEr (zafirlukast) marketed by AstraZeneca, the first leukotriene receptor antagonist to receive FDA clearance for the asthma. ... ccnmatthews.com

The science behind dietary omega-3 fatty acids  -  Jan 15, 2008
...ibuprofen), cyclooxygenase-2 (COX-2) inhibitors (eg, rofecoxib, celecoxib 12 ) and leukotriene antagonists (eg, montelukast, zafirlukast). ... CMAJ

Drug Treatment: Controller And Relievers  -  Mar 15, 2006
Leukotriene modifiers — Zafirlukast, zileuton or montelukast may be considered an alternative to low doses of inhaled corticosteroids for patients aged 12 ... Intelihealth.com

Article: Waiting to Inhale; As asthma cases soar, doctors are finally...  -  Mar 14, 2005
Thus, for example, Maccabi has told its doctors to use AstraZeneca's Accolate (zafirlukast) for asthma rather than Merck & Co's Singulair (montelukast), ... Pay-Per-View - Newsweek International - HighBeam Research

Asthma: Three steps to better asthma control  -  May 4, 2008
Examples include montelukast (Singulair) and zafirlukast (Accolate). • Cromolyn (Intal) and nedocromil (Tilade): These medications, taken by inhalation, ... Nation on Sunday

A case of fistulizing Crohn's disease and erythema nodosum managed …  -  Oct 5, 2007
...bromides, omeprazole, isotretinoin, zafirlukast and montelukast; infections (particularly tuberculosis, coccidiomycosis and streptococcal infection); ... Nature.com

AstraZeneca sues DRL over Accolate  -  Jul 9, 2008
In a suit filed on June 27 in the district court of New Jersey, AstraZeneca has accused DRL of infringing their patents for zafirlukast (Accolate) with ... Financial Express

Asthma.(disease overview)(Disease/Disorder overview)  -  May 24, 2006
...zafirlukast (Accolate), zileuton (Zyflo), or montelukast (Singulair) pills taken daily. * cromolyn or nedocromil, inhaled 3 to 4 times a day. ... $4.95 - Clinical Reference Systems - ECNext

ABC-transporters expressed on endothelial cell membranes efflux anti-...  -  Aug 26, 2008
...similar to MK-571, other leukotriene receptor antagonists, eg montelukast (SingulairTM) and zafirlukast (AccolateTM) can suppress MRP-mediated efflux of ... Genetic Engineering News - Genetic Engineering News (press release)

Mild asthma may not require daily medication  -  Apr 28, 2005
After an initial treatment period, participants were divided into three groups: One took budesonide (a corticosteroid inhaler); another took zafirlukast (a ... Pay-Per-View - The Record - ProQuest Archiver

What Can I Do To Beat Hay Fever?  -  Feb 3, 2007
Singular and Zafirlukast, which interfere with chemicals that cause the allergic reaction, also can help hay fever as well as asthma. ... Pay-Per-View - Tampa Tribune - ProQuest Archiver

No link between leukotriene modifiers, vasculitis.(Churg-Strauss …  -  Mar 1, 2006
...maintained by the Food and Drug Administration, found a strong association with zafirlukast and montelukast, though not with zileuton (Clin. Ther. ... Pay-Per-View - Internal Medicine News - Factiva, from Dow Jones

MUR tips for leukotriene receptor antagonists  -  Jan 5, 2008
The leukotriene receptor antagonists montelukast and zafirlukast are used in the treatment of chronic asthma. They may be used alone or with an inhaled ... Chemist & Druggist - Chemist+Druggist

Treating asthma/avoiding SVT.(CLINICAL TWISTERS)  -  Nov 20, 2006
...modifier such as montelukast or zafirlukast (Accolate, AstraZeneca). Sustained-release theophylline is not a viable option due to T.C.'s tachycardia. ... $4.95 - Drug Topics - ECNext

Few or no side effects from medications  -  Sep 27, 2008
Leukotriene modifiers, which include montelukast (Singulair) and zafirlukast (Accolate) and zileuton (Zyflo). Cromolyn, which may help prevent mild to ... MayoClinic.com

P&G spends big in attempt to lead bone health  -  Jul 4, 2007
The first to be marketed in the US was AstraZeneca's Accolate (zafirlukast) around 10 years ago, but now others have also been approved, including Merck ... DrugResearcher.com

Trial to assess head-to-head NSAIDs' cardiac risks: the independent, ...  -  Jan 15, 2006
Patients were then randomized to twice-daily oral placebo and inhalation of 200-meg budesonide, twice-daily oral 20-mg zafirlukast and placebo ... ... Pay-Per-View - Family Practice News - HighBeam Research

ABC-transporters Expressed On Endothelial Cell Membranes Efflux Anti-...  -  Aug 30, 2008
...similar to MK-571, other leukotriene receptor antagonists, eg montelukast (SingulairTM) and zafirlukast (AccolateTM) can suppress MRP-mediated efflux of ... sciencedaily.com

Daily asthma drugs not essential.(Brief Article)  -  Apr 15, 2005
The patients were assigned to take 200mu g of budesonide twice daily, 20mg of zafirlukast twice daily or a placebo inhaler. ... Free with registration - GP - AccessMyLibrary.com

GoogleReport.org provides new topic service  -  Jul 13, 2007
Accolate contains zafirlukast. It is made by AstraZeneca UK Limited. The information in this Medicine Guide for Accolate varies according to the condition ... geek.com

Are daily inhaled steroids appropriate for mild persistent asthma?(POI...  -  Mar 15, 2007
...corticosteroids guided by a symptom-based action plan, either alone or with daily ICS (budesonide) or zafirlukast (N. Engl. J. Med. 2005;352:1519-28). ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Butterbur for migraine prophylaxis.(Alternative medicine: an evidence...  -  Mar 15, 2005
...as was suggested by a reduction in attacks among patients with comorbid asthma given the leukotriene inhibitors montelukast and zafirlukast. ... Free with registration - Family Practice News - AccessMyLibrary.com

More work needed on LRAs, says DTB.(leukotriene receptor antagonists,...  -  Nov 5, 2005
The drug class - which includes montelukast and zafirlukast - comprises an option for people with exercise-induced bronchoconstriction, says the DTB. ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

Exercise-induced asthma: Avoid it with preventive medication  -  Nov 23, 2005
A leukotriene modifier, such as montelukast sodium (Singulair) or zafirlukast (Accolate), for effects lasting up to 24 hours. These drugs are helpful in ... MSN Health & Fitness

Asthma Drug Worse Than Placebo, Symptoms Worsen on Withdrawal  -  May 30, 2008
...(NaturalNews) Asthma symptoms worsen on withdrawal of the drug Accolate (zafirlukast). Benefits are seen for only the first five weeks, after which symptoms ... Natural News.com

Mild Persistent Asthma and Inhaled Corticosteroids  -  Jun 29, 2005
...budesonide and oral placebo tablets, twice-daily oral zafirlukast and inhaled placebo, or twice-daily oral and inhaled placebo (intermittent treatment). ... Medscape

How to take Ziprasidone from Consumer Reports Health.  -  Jan 4, 2007
...verapamil (Calan, Covera, Isoptin, Verelan); and zafirlukast (Accolate). Your doctor may need to change the doses of your medications or monitor you ... consumerreports.org

It's All About Control  -  Mar 2, 2005
...pathway of arachidonic acid metabolism (zileuton), or by preventing leukotrienes from binding to their receptors (montelukast and zafirlukast). ... news Stories

Anti-inflammatory Drugs Offer Promise  -  May 1, 2005
The first of the new advances has been the introduction of cysteinyl leukotriene antagonists montelukast and zafirlukast and the 5-lipoxygenase inhibitor ... news Stories

Daily Asthma Drugs Not Essential  -  May 1, 2005
The patients were assigned to take 200g of budesonide twice daily, 20mg of zafirlukast twice daily or a placebo inhaler. All of the patients were told that ... RedOrbit

Mild asthma may not require daily drugs  -  May 30, 2005
...containing the asthma drug budesonide, twice-daily doses of zafirlukast(an asthma medication taken in pill form)or inactive placebo pills or inhalers. ... macleans.ca

TH - Feature Stories Article  -  Jul 28, 2008
A leukotriene modifier such as montelukast sodium (Singulair) or zafirlukast (Accolate), for effects lasting up to 24 hours. ... Dubuque Telegraph Herald

Safety, Tolerability, and Exploratory Efficacy of Montelukast in 6-...  -  Jul 13, 2005
Leukotriene-receptor antagonists [montelukast, pranlukast, and zafirlukast] and 5-lipoxygenase inhibitors (zileuton) block the action or inhibit synthesis ... RedOrbit

Study shows symptom-driven therapy may be ok for some adults with...  -  Apr 8, 2005
Two groups were assigned to long-term control medication taken twice daily -- either an inhaled steroid (budesonide) or a leukotriene modifier (zafirlukast) ... PsychCentral.com

Can asthma patients blow off their daily preventive therapy?  -  May 30, 2005
...inhaled steroid (daily budesonide plus intermittent therapy) or oral leukotriene-receptor antagonist (daily zafirlukast plus intermittent therapy). ... National Review of Medicine

Ghana Football Association ::: Print News  -  Feb 24, 2007
Zafirlukast and, Churg-Strauss syndrome associated with the allergen was exhausted. When montelukast is of CAFTA and have liver, disease? ... Ghana Football Association

Relief for common allergies.(Medical condition overview)  -  Dec 1, 2005
Also available are several medications for long-term prevention, including formoterol (Foradil), montelukast (Singulair), salmeterol (Serevent), zafirlukast ... Free with registration - PDR Family Guide to Prescription Drugs... - AccessMyLibrary.com

DTB reviews new evidence on asthma treatment, UK  -  Nov 7, 2005
The evidence now available suggests that the leukotriene receptor antagonists, montelukast and zafirlukast, are suitable as add-on treatment in patients ... Medical News Today - Medical News Today (press release)

Last reviewed by Faculty of Harvard Medical School on May 26, 2009  -  Jan 11, 2007
...and "sound good" — you might wonder how the asthma medications zafirlukast and montelukast became the generic names for Accolate and Singulair. ... Intelihealth.com

Asthma.(Women's Health Advisor 2006)(Disease/Disorder overview)  -  Nov 1, 2006
...zafirlukast (Accolate), zileuton (Zyflo), or montelukast (Singulair) pills taken daily. * cromolyn or nedocromil, inhaled 3 to 4 times a day. ... $4.95 - Clinical Reference Systems - ECNext

Asthma.(Adult Health Advisor 2007)(Disease/Disorder overview)  -  May 31, 2007
...zafirlukast (Accolate), zileuton (Zyflo), or montelukast (Singulair) pills taken daily. * cromolyn or nedocromil, inhaled 3 to 4 times a day. ... $4.95 - Clinical Reference Systems - ECNext

Federal Register 2008 - 73 FR 51829 Publication of Guidances for …  -  Sep 5, 2008
Tramadol HCl (60) Trospium Chloride (61) Varenicline Tartrate (62) Zafirlukast (63) Zalcitabine (64) Zileuton (65) Zolmitriptan (66) Zonisamide III. ... Pay-Per-View - Federal Register 2008 - Loislaw

Meda AB's Alstelpro.(Pipeline) | Article from Medical Marketing &...  -  Nov 1, 2008
Zafirlukast AstraZeneca Seasonal allergic rhinitis (Filed) Carperitide Asubio Adult ... Medical Marketing & Media. Article: Collegium received FDA approval ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Are daily inhaled steroids appropriate for mild persistent asthma?...  -  Feb 15, 2007
...corticosteroids guided by a symptom-based action plan, either alone or with daily ICS (budesonide) or zafirlukast (N. Engl. J. Med. 2005;352:1519-28). ... Pay-Per-View - Family Practice News - HighBeam Research

Case report: urticaria following intentional ingestion of cicadas.(Let...  -  Jun 1, 2005
The medications he was taking included fluticasone nasal spray, inhaled fluticasone/salmeterol, zafirlukast, and tamsulosin. He had taken his scheduled ... Pay-Per-View - American Family Physician - Factiva, from Dow Jones

Levemir, Rozerem.(NEW & APPROVED) | Article from Internal Medicine …  -  Aug 15, 2005
Patients were then randomized to twice-daily oral placebo and inhalation of 200-mcg budesonide, twice-daily oral 20-mg zafirlukast and placebo ... ... Pay-Per-View - Internal Medicine News - HighBeam Research

Treating allergies & asthma.  -  Aug 1, 2005
Tablets Accolate Prescription (zafirlukast), Singulair (montelukast), Zyflo (zileuton) Anticholinergics. Block the effects of chemicals that stimulate mucus ... $4.95 - National Women's Health Report - ECNext

Daily steroids 'not needed' in asthma.  -  Apr 19, 2005
Researchers randomised 225 patients to inhaled budesonide 200 micrograms twice daily, oral zafirlukast (Accolate) 20mg twice-daily, or placebo twice daily. ... Pay-Per-View - Doctor - Factiva, from Dow Jones

Case report: urticaria following intentional ingestion of cicadas.(Let...  -  Jun 1, 2005
The medications he was taking included fluticasone nasal spray, inhaled fluticasone/salmeterol, zafirlukast, and tamsulosin. He had taken his scheduled ... $4.95 - American Family Physician - ECNext

Butterbur for migraine prophylaxis.(Alternative medicine: an evidence...  -  Mar 15, 2005
...as was suggested by a reduction in attacks among patients with comorbid asthma given the leukotriene inhibitors montelukast and zafirlukast. ... Pay-Per-View - Family Practice News - HighBeam Research

Article: Drug brings hope for asthma sufferers - The Independent -...  -  Oct 19, 2007
...about three million asthma sufferers in Britain, 750000 of them ... has been a big problem with asthma sufferers. But patients taking zafirlukast ... ... Pay-Per-View - Independent - London - HighBeam Research

Reports of suicidality in patients using Singulair to be investigated....  -  Apr 15, 2008
Three of these agents are on the market now: montelukast (Singulair), zafirlukast (Accolate), and zileuton (Zyflo). Montelukast ... financial support from ... Pay-Per-View - Family Practice News - HighBeam Research

AstraZeneca Pledges More Than $1 Million in Contributions and …  -  Sep 1, 2005
These medicines include: ACCOLATE(R) (zafirlukast), ARIMIDEX(R) (anastrozole), ATACAND(R) (candesartan cilexetil), ATACAND HCT(R) (candesartan ... $4.95 - PR Newswire - ECNext

asthma -- Britannica Online Encyclopedia  -  Jun 5, 2008
...which are bronchodilators; and zileuton and zafirlukast, which are leukotriene modifiers. Quick-relief medications may include bronchodilators, ... Subscription - Encyclopedia Britannica

Brand Names/Synonyms:
Zafirlukast is also known by the following brand names and/or synonymsAccolate; CHEMBANK1613; Zafirlukast; Zafirlukast [Usan:Ban:Inn]

Drug Category:
Zafirlukast is categorized under the following by the FDA: Anti-Asthmatic Agents; Leukotriene Antagonists; ATC:R03DC01

Dosage Forms:
TABLET

Absorption:
Rapidly absorbed following oral administration, reduced following a high-fat or high-protein meal

Interactions:
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Chemical IUPAC Name:
cyclopentyl [3-[[2-methoxy-4-[(2-methylphenyl)sulfonylcarbamoyl]phenyl]methyl]-1-methyl-indol-5-yl]aminoformate





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