Zaleplon

This page contains recent news articles, when available, and an overview of Zaleplon but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Zaleplon
(when available)

Pharmacology and use:
Zaleplon is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class and is indicated for the short-term treatment of insomnia. While Zaleplon is a hypnotic agent with a chemical structure unrelated to benzodiazepines, barbiturates, or other drugs with known hypnotic properties, it interacts with the gamma-aminobutyric acid-benzodiazepine (GABABZ) receptor complex. Subunit modulation of the GABABZ receptor chloride channel macromolecular complex is hypothesized to be responsible for some of the pharmacological properties of benzodiazepines, which include sedative, anxiolytic, muscle relaxant, and anticonvulsive effects in animal models. Zaleplon binds selectively to the brain alpha subunit of the GABA A omega-1 receptor. For the treatment of short-term treatment of insomnia in adults

Mechanism Of Action:
Zaleplon exerts its action through subunit modulation of the GABABZ receptor chloride channel macromolecular complex.Zaleplon binds selectively to the brain alomega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding.

News Articles on Zaleplon

Scots get £1m of drugs to treat sleep disorders  -  ‎Dec 30, 2009‎
The Scottish Government yesterday said most prescriptions were for benzodiazepines and another group of drugs – Zaleplon, Zolpidem and Zopiclone. ... Aberdeen Press and Journal

Alexza Announces Submission of AZ-004 (Staccato(R) Loxapine) NDA  -  ‎Dec 14, 2009‎
Product candidates that have completed Phase 1 testing are AZ-003 (Staccato fentanyl) for the treatment of breakthrough pain, and AZ-007 (Staccato zaleplon) ... CNNMoney.com (press release)

Alexza anuncia la presentación de la NDA de AZ-004 Loxapina)  -  ‎Dec 15, 2009‎
Los productos candidatos que han completado la prueba de fase 1 son AZ-003 (Staccato fentanil) para el tratamiento del dolor, y AZ-007 (Staccato zaleplon) ... Finanzas.com

Thuốc ngá»§ thế hệ má»›i cÅ©ng không ít tác dụng phụ  -  ‎Dec 16, 2009‎
Chỉ riêng zaleplon có cÆ¡ chế tác dụng khác hÆ¡n tạo ra giấc ngá»§ giống giấc ngá»§ tá»± nhiên. Tuy mức độ các nhược Ä‘iểm cá»§a các thuốc gây ngá»§ thế hệ má»›i gây ra có ... Báo Hoà Bình

Alexza gibt Einreichung einer NDA fur AZ-004 (Staccato(R) Loxapine) bekannt  -  ‎Dec 15, 2009‎
...sind AZ-003 (Staccato fentanyl) zur Behandlung von Durchbruchschmerzen und AZ-007 (Staccato zaleplon) zur Behandlung von Schlaflosigkeit. ... PR-Inside.com (Pressemitteilung)

Alexza annonce la présentation de nouveau médicament concernant l'AZ-004 ...  -  ‎Dec 15, 2009‎
...phase 1 sont l'AZ-003 (Staccato fentanyl) pour le traitement des percées de douleur, et l'AZ-007 (Staccato zaleplon) pour le traitement de l'insomnie. ... Capital.fr

Alexza Reports 2009 Third Quarter Financial Results and Updates AZ-004 ...  -  ‎Nov 9, 2009‎
Product candidates that have completed Phase 1 testing are AZ-003 (Staccato fentanyl) for the treatment of breakthrough pain, and AZ-007 (Staccato zaleplon) ... CNNMoney.com (press release)

Alexza to Announce 2009 Third Quarter Financial Results and Update Its AZ-004 ...  -  ‎Nov 2, 2009‎
Product candidates that have completed Phase 1 testing are AZ-003 (Staccato fentanyl) for the treatment of breakthrough pain, and AZ-007 (Staccato zaleplon) ... Reuters

Esce a metà novembre un doppio di inediti e pezzi live dei BELLE & SEBASTIAN  -  ‎Oct 21, 2009‎
...birth control). prescription drugs without a prescription who has phentermine Zaleplon is used to treat short-term difficulty in falling asleep. ... ImpattoSonoro

Attenti ai farmaci per l'insonnia  -  ‎Oct 22, 2009‎
Si tratta dello zolpidem e dello zaleplon, medicine che esauriscono in poche ore la loro attività e, quindi, possono assumersi anche nel caso di risvegli ... Italiasalute.it

Mylan gets final FDA approval for Zaleplon capsules  -  Jun 9, 2008
SAN FRANCISCO (Thomson Financial) - Mylan Inc. said Monday its Genpharm ULC subsidiary has received final approval from the Food and Drug Administration for ... Forbes

Aurobindo Pharma gets FDA nod for Zaleplon generic insomnia capsules  -  Jun 10, 2008
MUMBAI (Thomson Financial) - India's Aurobindo Pharma Ltd. said it received a final approval from the US Food and Drug Administration to manufacture and ... Forbes

Zaleplon (Systemic).(Drug overview)  -  May 1, 2006
Zaleplon ( ZAL -- e -- plon) belongs to the group of medicines called central nervous system (CNS) depressants (medicines that make you drowsy or less ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Zaleplon (Systemic).  -  Aug 1, 2006
Zaleplon ( ZAL -- e -- plon) belongs to the group of medicines called central nervous system (CNS) depressants (medicines that make you drowsy or less ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

The Hindu Business Line  -  Jun 12, 2008
Zaleplon is indicated for the short-term treatment of insomia. Zaleplon capsules are generic equivalent of Kings Pharmaceuticals Sonata Capsules. ... Hindu Business Line

Learn about Zaleplon from Consumer Reports Health.  -  Jan 10, 2008
Zaleplon is used to treat insomnia (difficulty falling asleep). Zaleplon does not help you to stay asleep longer or decrease the number of times that you ... consumerreports.org

… Announces Final FDA Approval for Zaleplon Capsules. - PR Newswire...  -  Jun 9, 2008
Mylan Announces Final FDA Approval for Zaleplon Capsules. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

How to take Zaleplon from Consumer Reports Health.  -  Jan 10, 2008
...tell your doctor and pharmacist if you are allergic to zaleplon, aspirin, any other medications, or tartrazine (a yellow dye in some processed foods and ... consumerreports.org

Teva gets tentative US OK for generic zaleplon.  -  Dec 5, 2005
Israeli drugmaker Teva Pharmaceutical Industries has been granted tentative approval for its Abbreviated New Drug Application for zaleplon capsules, ... $4.95 - Pharma Marketletter - ECNext

… Announces Positive Phase 1 Results With AZ-007 (Staccato(R) Zaleplo...  -  Apr 29, 2008
Zaleplon exposure was dose proportional across the 4 doses studied, ... Moreover, by coupling the shorter half-life of zaleplon with the lower dose enabled ... FierceBiotech

Taking Zaleplon from Consumer Reports Health.  -  Jan 10, 2008
Zaleplon may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:. Some side effects can be serious. ... consumerreports.org

Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 Clinical Trial...  -  Feb 5, 2008
MOUNTAIN VIEW, Calif., Feb. 5 /PRNewswire-FirstCall/ -- Alexza Pharmaceuticals, Inc. announced today that it has initiated a Phase 1 clinical trial with ... Free with registration - PR Newswire - AccessMyLibrary.com

Loislaw Federal District Court Opinions - KING PHARMACEUTICALS, …  -  Jan 22, 2007
I. BACKGROUND This is an action for patent infringement of the 538 Patent,[fn2] under which King has the right, inter alia, to sell prescription zaleplon ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 Clinical Trial...  -  Feb 6, 2008
Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA) announced that it has initiated a Phase 1 clinical trial with AZ-007 (Staccato(R) zaleplon). ... Medical News Today - Medical News Today (press release)

Loislaw Federal District Court Opinions - KING PHARMACEUTICALS v. …  -  Jan 20, 2006
77-239 indicates that the zaleplon capsules Teva seeks to market are bioequivalent to King's Sonata® drug products, have the same active ingredient, ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

… Laboratories, Inc. Announces the Launch of Zaleplon Capsules CIV. ...  -  Jun 6, 2008
Roxane Laboratories, Inc. Announces the Launch of Zaleplon Capsules CIV. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

King Pharmaceuticals, Inc. v. Teva Pharmaceuticals USA, Inc., 409 F. …  -  Jan 20, 2006
77-239 indicates that the zaleplon capsules Teva seeks to market are bioequivalent to King's Sonata(r) drug products, have the same active ingredient, ... $2.95 - U.S. District Court, District of New... - VersusLaw

Somnus Therapeutics Completes Phase I Study of Sleep Maintenance …  -  Dec 11, 2008
SKP-1041 is a new formulation of zaleplon, a non-benzodiazepine hypnotic agent, ... “Both companies are confident that the Geoclock™ version of zaleplon has ... Genetic Engineering News - Genetic Engineering News (press release)

[U] King Pharmaceuticals, Inc. v. Teva Pharmaceuticals USA, Inc., No....  -  Aug 3, 2007
This is an action for patent infringement of the 538 Patent,*fn3 under which King has the right, inter alia, to sell prescription zaleplon drug products in ... $2.95 - U.S. District Court, District of New... - VersusLaw

Drugged vs Drowsy Driving  -  Nov 3, 2005
Research showed zolpidem and zaleplon to be relatively safe. ... The use of zaleplon, but not zolpidem, also appeared safe when driving as soon as 4 hours ... Sleep Review

… Release: Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1...  -  Feb 5, 2008
Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 Clinical Trial and Updates Clinical Pipeline Development Status. from PR Newswire. Pay-Per-View - PR Newswire - HighBeam Research

Zaleplon capsules.  -  Jul 14, 2008
Zaleplon capsules. Teva, Mylan, and Roxane Laboratories (www.roxane. com) have all launched zaleplon capsules, CIV, generic versions of Sonata from King ... $9.94 - Drug Topics - Alacra Store

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...ã€?Zaleplonã€?Zolpidemã€?Zopicloneç­‰å??五項æˆ?份。 在明年二月二å??å…«æ—¥å‰?,上述藥å“? 的仿單應加刊「 æœ?用本å“?å?¯èƒ½å‡ºç?¾å¤¢é?Šè¡Œç‚ºï¼Œä¾‹å¦‚開車ã€?打電話å?Šæº–備與食用食物ã€? ... epochtimes.com

חברת טבע קיבלה ×?ישור להפצת תרופה לנדודי שינה  -  Dec 1, 2005
...מותנה מה-FDA לייצר ולשווק כמוסות של התרופה זלפלון (Zaleplon) המשמשת לטיפול בנדודי שינה. ... רפו×?×”

Insomnia Medications - Insomnia Health Information - NY Times Health  -  Feb 6, 2008
It lasts longer than zaleplon. Patients should not take it unless they plan on ... Because they are short-acting, zaleplon and zolpidem may pose fewer risks ... New York Times

Hypnotics for Insomnia: An Expert Interview With Milton K. Erman  -  Aug 26, 2005
Zolpidem and zaleplon had short half-lives and therefore were capable of promoting sleep and promoting sleep initiation, but didn't have an adequate ... Medscape

Neurocrine Announces Peer-Reviewed Publication of Indiplon …  -  Apr 5, 2006
Zopiclone and zaleplon showed little or no subtype selectivity, and zolpidem showed moderate selectivity for alpha 1 versus alpha 2 and 3 containing ... Free with registration - PR Newswire - AccessMyLibrary.com

Treatment options for insomnia.(Disease/Disorder overview)(Clinical …  -  Aug 15, 2007
...(17) Zaleplon causes less memory and psychomotor impairment than do benzodiazepines and ... Quick reference guide: zaleplon, zolpidem and zopiclone for the ... $4.95 - American Family Physician - ECNext

STEPS - June 15, 2005 - American Family Physician  -  Jun 15, 2005
The duration of action of eszopiclone is approximately eight hours, similar to zolpidem (Ambien) and longer than zaleplon (Sonata). ... AAFP News Now

Closing Bell- Market Live-Stocks-Markets-The Economic Times  -  Jun 11, 2008
Zaleplon is indicated for the short-term treatment of insomia. Zaleplon capsules are generic equivalent of Kings Pharmaceuticals' Sonata Capsules. ... Economic Times

Interactions  -  Mar 13, 2007
Newer agents such as ramelteon (Rozerem) and zaleplon (Sonata) have not been associated with the "next-day sluggishness" that was associated with older ... Pay-Per-View - Washington Post - ProQuest Archiver

… Phase 1 Results With AZ-007 (Staccato(R) Zaleplon). - PR Newswire...  -  Apr 29, 2008
Zaleplon exposure was dose proportional across the 4 doses studied, as calculated by power analysis. Pharmacodynamics, measured as sedation assessed on a ... Pay-Per-View - PR Newswire - HighBeam Research

THE HEALTHY TRAVELER; New weapons in travelers' round-the-clock …  -  Apr 23, 2006
Sonata (zaleplon) is better when a person has limited time to sleep, say five or six hours." DON'T SLEEP THROUGH VACATION: The sleeping pills Ambien, ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Article: Comorbid insomnia/depression responds to cotherapy.(Psychiatr...  -  Sep 1, 2005
It is ... both zolpidem and zaleplon. Dosing of eszopiclone should begin at 2 mg for nonelderly ... Drug Formulary Review ... Pay-Per-View - Internal Medicine News - HighBeam Research

Press Release: Alexza Selected to Join Russell 3000(R) Index. - PR …  -  Jun 22, 2007
Staccato loxapine (AZ-004), which is ... with panic disorder, AZ-003 (Staccato fentanyl ... with acute pain and AZ-007 (Staccato zaleplon . ... Pay-Per-View - PR Newswire - HighBeam Research

Wisconsin Administrative Code - CSB 2.25 Addition of remifentanil to ...  -  Jul 16, 2005
...(5) Section 961.20 (2) (o) and (p), Stats., is created to read: (o) Zaleplon. (p) Zolpidem. (6) Section 961.20 (2m) (at), (bu) and (f), Stats., ... Pay-Per-View - Wisconsin Administrative Code - Loislaw

Somnus Therapeutics Completes Phase I Study Of Sleep Maintenance …  -  Dec 15, 2008
SKP-1041 is a new formulation of zaleplon, a non-benzodiazepine hypnotic agent, ... "Both companies are confident that the Geoclockâ„¢ version of zaleplon has ... Medical News Today - Medical News Today (press release)

Press Release: Alexza Reports Second Quarter Financial Results and …  -  Aug 13, 2007
Article: Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 ... PR Newswire; February 5, 2008 ; 700+ words ... ... has initiated a Phase 1 clinical ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Alexza Reports Third Quarter Financial Results and …  -  Nov 1, 2007
This product candidate, AZ-007 (Staccato zaleplon), is being developed for the ... Article: Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 ... ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Alexza's Corporate Presentation to be Webcast at the …  -  Jan 31, 2008
Pharmaceuticals in North America, and AZ-007 (Staccato zaleplon ... presentation will contain forward-looking statements that involve significant risks ... ... Pay-Per-View - PR Newswire - HighBeam Research

Insomnia.(DRUG UPDATE)  -  Jul 1, 2006
Immediate-release zolpidem and zaleplon are approved only for short-term use (fewer than 30 days), but are sometimes used long term under physician ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Aurobindo's insomnia drug gets FDA nod  -  Jun 10, 2008
Mumbai: Pharmaceutical firm Aurobindo Pharma on Tuesday said it has received US regulatory approval to market Zaleplon capsules, used in the treatment of ... सिफी - सिफी

Pharmacologic management of chronic insomnia.(Review Article)(Clinical...  -  Dec 1, 2006
Zaleplon (Sonata), like zolpidem, binds to the GAB[A.sub.A] receptor benzodiazepine site but with less affinity. It has an onset of action of 20 minutes, ... Free with registration - Southern Medical Journal - AccessMyLibrary.com

Trattamento dell'insonnia negli anziani: ipnotici non-benzodiazepinici  -  Sep 18, 2007
Zaleplon e Ramelteon offrono il vantaggio, rispetto agli altri ipnotici, ... Sulla base dei dati clinici disponibili, Zopiclone, Zolpidem, Zaleplon, ... XagenaSalute

Questions & Answers.(sleep medication)  -  Apr 1, 2005
Of the three, zaleplon has the shortest half-life, so it may be best when the main problem is getting to sleep, or when you don't want to sleep for more ... $4.95 - Harvard Mental Health Letter - ECNext

Pharmacy update: Head for bed.(treatment for sleep disorder)  -  Jan 28, 2006
Zaleplon has an elimination half-life of one hour so is appropriate for patients with difficulty in falling asleep.1 It is indicated if the patient's ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

Q: What can I do about insomnia?(When the Patient Asks)(Disease/ …  -  Nov 1, 2007
Zaleplon is a good alternative for patients with prolonged sleep latency. (4) The newest pharmacologic agent is ramelteon, a nonscheduled melatonin agonist ... Free with registration - JAAPA-Journal of the American Academy... - AccessMyLibrary.com

Melatonin.(Monograph)  -  Dec 1, 2005
The sleep-inducing potential of test medications (in decreasing order of effect) was: zopiclone>zaleplon>melatonin >temazepam. (66) The researchers (using ... Free with registration - Alternative Medicine Review - AccessMyLibrary.com

Press Release: Merrill Lynch Global Pharmaceutical, Biotechnology & …  -  Jan 29, 2008
Staccato loxapine (AZ-004), which is ... with panic disorder, AZ-003 (Staccato fentanyl ... with acute pain and AZ-007 (Staccato zaleplon . ... Pay-Per-View - PR Newswire - HighBeam Research

As some sleeping pills double your risk of a car crash, the experts...  -  Dec 1, 2008
Zaleplon can help you get back to sleep within 20 minutes.' Cons: They are recommended only for short-term use because of the risk of addiction and ... Daily Mail

Article: Insomnia.(Drug Update) - Skin & Allergy News | HighBeam …  -  Sep 1, 2006
Immediate-release zolpidem and zaleplon are approved only for short-term use (fewer than 30 days), but are sometimes used long term under physician ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Kentucky Regulations - 902 KAR 55:030. Schedule IV substances. [ …  -  Aug 10, 2005
...(35) Prazepam; (36) Quazepam; (37) Temazepam; (38) Tetrazepam; (39) Triazolam; (40) Zaleplon; (41) Zolpidem; and (42) Zopiclone. Section 3. Fenfluamine. ... Pay-Per-View - Kentucky Regulations - Loislaw

Stop losing sleep over insomnia.(CONTINUING EDUCATION)(Statistical …  -  Jul 9, 2007
The recommended dose of zaleplon is 10 mg at bedtime (5 mg in the elderly). Zaleplon has minimal drug interactions. It is primarily metabolized via aldehyde ... $4.95 - Drug Topics - ECNext

Article: Ramelteon improves chronic insomnia in elderly.(Geriatric …  -  Aug 1, 2005
Ambien), eszopiclone (Lunesta), ramelteon (Rozerem), zaleplon (Sonata), or ... was the degree of oxygen saturation. Ramelteon is a selective MT1/MT2 ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Press Release: Alexza Initiates AZ-003 Phase I Clinical Trial. - PR …  -  Apr 26, 2006
Staccato loxapine (AZ-004), which is ... with panic disorder, AZ-003 (Staccato fentanyl ... with acute pain and AZ-007 (Staccato zaleplon . ... Pay-Per-View - PR Newswire - HighBeam Research

FDA approves a new, nonnarcotic sleep aid.(Psychiatry) | Article from...  -  Jan 15, 2005
Internal Medicine News; September 15, 2005 ; 700+ words ... ... zaleplon (Sonata), and eszopiclone (Lunesta)--with ... nightly 1- or 2-mg eszopiclone or ... Pay-Per-View - Internal Medicine News - HighBeam Research

Merger and Acquisition Scenario  -  May 12, 2007
AZ-007 (Staccato Zaleplon). Pain Management. Phase I/Phase II Clinical Stage Products. Therapeutics that are being investigated for the treatment of pain in ... $250.00 - Revere Reports - Revere

Press Release: TAXUS II Clinical Trial Follow-Up Data Demonstrates …  -  Sep 5, 2006
Application for an extended release formulation of Sonata(R) (zaleplon), a ... select the most effective extended release formulation of Sonata(R) utilizing ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Alexza Pharmaceuticals to Present AZ-001 Phase IIb …  -  May 31, 2007
Staccato loxapine (AZ-004), which is ... with panic disorder, AZ-003 (Staccato fentanyl ... with acute pain and AZ-007 (Staccato zaleplon . ... Pay-Per-View - PR Newswire - HighBeam Research

Drug improves sleep induction without sedation.(Drug overview) |...  -  Oct 1, 2005
Ambien), eszopiclone (Lunesta), ramelteon (Rozerem), zaleplon (Sonata), or ... was the degree of oxygen saturation. Ramelteon is a selective MT1/MT2 ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Press Release: Neurocrine Announces Peer-Reviewed Publication of …  -  Apr 5, 2006
...for alpha 1 containing GABA-A receptors compared to the currently marketed non-benzodiazepine sleep agents zolpidem (Ambien(R)), zaleplon (Sonata(R)) . ... Pay-Per-View - PR Newswire - HighBeam Research

Mylan Partners on MS Drug Distribution, Launches Insomnia Product  -  Jun 18, 2008
Word of the agreement came a day after Mylan subsidiary Genpharm won final FDA approval for its ANDA for zaleplon capsules 5 and 10 mg, a treatment for ... FDA news - FDA news (subscription)

Alexza Advances 2 More Drugs  -  Apr 30, 2008
This phase 1 compound, Staccato zaleplon, is a formulation of King ... The phase 1 clinical trial for Staccato zaleplon was only a short-term safety study ... fool.com

Insomnia in elderly: medicate with care; Many clinicians prefer …  -  Oct 1, 2007
Zaleplon [Sonata] is indicated for sleep initiation, but because of its short half-life it does not improve sleep maintenance. However, its short half-life ... $4.95 - Clinical Psychiatry News - ECNext

It was the Ambien, your honor.(Indications)(insomnia medications and ...  -  Apr 15, 2006
Rozerem), zaleplon (Sonata), and low-dose (25-75 mg) trazodone (Desyrel), all risk factor C, and zolpidem (Ambien), risk factor B. The use for sleep of the ... Pay-Per-View - Family Practice News - HighBeam Research

Article: New hope for insomnia.  -  Mar 22, 2005
Scientists know that the cyclopyrrolones zolpidem and zaleplon bind with the omega1 site but are unsure if eszopiclone also binds with only the omega1 site. ... Pay-Per-View - FOCUS: Journal for Respiratory Care... - HighBeam Research

It was the Ambien, your honor.(INDICATIONS) | Article from Internal …  -  Apr 15, 2006
Rozerem), zaleplon (Sonata), and low-dose (25-75 mg) trazodone (Desyrel), all risk factor C, and zolpidem (Ambien), risk factor B. The use for sleep of the ... Pay-Per-View - Internal Medicine News - HighBeam Research

Abundance of insomnia therapies in the pipeline.(Neuropsychiatric …  -  Dec 1, 2005
New benzodiazepine receptor agonists for chronic insomnia--zaleplon ... treating chronic insomnia with CBT, and ... Although CBT and benzodiazepine receptor ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Press Release: Alexza Pharmaceuticals to Present AZ-004 Phase 2a …  -  May 1, 2008
Staccato loxapine (AZ-004), which is ... with panic disorder, AZ-003 (Staccato fentanyl ... with acute pain and AZ-007 (Staccato zaleplon . ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Roxane Laboratories, Inc. - Company Snapshot - AlacraStore.com  -  Nov 6, 2008
Zaleplon capsules. Drug Topics, Jul 14 2008, $9.95 …Teva, Mylan, and Roxane Laboratories (www.roxane. com) have all launched zaleplon capsules, CIV, ... Pay-Per-View - co - Alacra Store

Merger and Acquisition Scenario  -  Feb 9, 2008
Target. AZ-001 (Inhaled Staccato Prochlorperazine); AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine) ... $250.00 - Revere Reports - Revere

Press Release: Alexza Pharmaceuticals to Present AZ-104 Phase 2a …  -  Jun 23, 2008
Staccato loxapine (AZ-004), which is ... with panic disorder, AZ-003 (Staccato fentanyl ... with acute pain and AZ-007 (Staccato zaleplon . ... Pay-Per-View - PR Newswire - HighBeam Research

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Mar 29, 2008
AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

Mylan Inc. - Company Snapshot - AlacraStore.com  -  Nov 5, 2008
Zaleplon capsules. Drug Topics, Jul 14 2008, $9.95 …Teva, Mylan, and Roxane Laboratories (www.roxane. com) have all launched zaleplon capsules, CIV, ... Pay-Per-View - co - Alacra Store

Merger and Acquisition Scenario  -  May 10, 2008
Target. AZ-002 (Staccato Alprazolam); AZ-007 (Staccato Zaleplon); AZ-104 (Low-Dose Staccato Loxapine); AZ-001 (Inhaled Staccato Prochlorperazine) ... $250.00 - Revere Reports - Revere

FDA tentative generics approvals--2005.(Special Report)(Illustration)  -  Feb 27, 2006
10 mg/ml Aurobindo Pharma Ltd. Zaleplon capsules, 5 mg and 10 mg Roxane Laboratories Inc. Bupropion HCl extended-release Anchen Pharmaceuticals tablets ... Free with registration - Chain Drug Review - AccessMyLibrary.com

Фармакологично лечение на безÑ?ънието ::: DoctorBG.com :::  -  Aug 21, 2008
Примери за небензодиазепини Ñ?а: eszopiclone, zaleplon и zolpidem. ОÑ?къдни данни подкрепÑ?Ñ‚ комбинирането на нефармакологичните Ñ? фарнакологичните подходи. ... DoctorBG.com

FDA tentative generics approvals--2005.(Special Report)(Illustration)...  -  Feb 27, 2006
10 mg/mlAurobindo Pharma Ltd. Zaleplon capsules, 5 mg and 10 mg Roxane Laboratories Inc. Bupropion HCl extended-releaseAnchen Pharmaceuticals tablets ... Pay-Per-View - Chain Drug Review - HighBeam Research

Hitmaker Dallas Austin Imprisoned In Dubai On Drug Charges  -  Jun 26, 2006
The sources also said that Austin may have possessed the sleeping aid Ambien (also called Sonata or Zaleplon), which is not considered a narcotic but is on ... MTV.com

Special to CNN.com  -  Dec 8, 2005
Taking prescription sleeping pills, such as zolpidem (Ambien), eszopiclone (Lunesta), zaleplon (Sonata) or ramelteon (Rozerem), for a couple of weeks until ... cnn.com

Old drugs get a new lease of life  -  Jul 10, 2008
And zaleplon, a sedative used on insomniacs, had the same effect as mirazapine, another antidepressant, while the antidepressant Prozac had similar effects ... Telegraph.co.uk

Restless legs syndrome  -  Feb 15, 2006
Commonly used sedatives for RLS include clonazepam (Klonopin), eszopiclone (Lunesta), ramelteon (Rozerem), temazepam (Restoril, Razapam), zaleplon (Sonata) ... cnn.com

Insomnia treatment: Cognitive behavioral therapy instead of sleeping...  -  Dec 21, 2006
...especially the relatively new class of drugs that includes zolpidem (Ambien), eszopiclone (Lunesta) and zaleplon (Sonata), may be of help. ... cnn.com

Press Release: Alexza Updates Status of Development Pipeline and …  -  Feb 8, 2007
Article: Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 ... PR Newswire; February 5, 2008 ; 700+ words ... ... has initiated a Phase 1 clinical ... Pay-Per-View - PR Newswire - HighBeam Research

Stilnox status unchanged  -  Feb 21, 2008
Z-class drugs - zolpidem, zopiclone and zaleplon - are all non-benzodiazepine hypnotics that are used as an alternative to drugs such as valium and rohypnol ... Sydney Morning Herald

Press Release: Phase 2 Results of Rigel's R788 Show Clinical Benefit...  -  Dec 7, 2008
Article: Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 Clinical ... PR Newswire; February 5, 2008 ; 700+ words ... ... today that it has initiated ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Alexza Pharmaceuticals Expands Staccato(R) Migraine …  -  Jun 20, 2007
Article: Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 ... PR Newswire; February 5, 2008 ; 700+ words ... ... has initiated a Phase 1 clinical ... Pay-Per-View - PR Newswire - HighBeam Research

Comorbidities flag sleep disorders.(Clinical Capsules)(Brief article)...  -  Apr 1, 2008
Article: Long-Term Zaleplon Appears Safe, Effective for Sleep . ... HAMBURG, GERMANY -- Zaleplon, a new sleep medication recently approved for sale in the ... Pay-Per-View - Family Practice News - HighBeam Research

Press Release: Light Sciences Oncology Completes Patient Enrollment...  -  Nov 25, 2008
Article: Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 Clinical ... PR Newswire; February 5, 2008 ; 700+ words ... ... today that it has initiated ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: CHMP Recommends Authorization to Market Preotact(R) …  -  Feb 23, 2006
Article: American Home Products' Sonata(R) (Zaleplon), First in a New ... PR Newswire; March 17, 1999 ; 700+ words ... ... announced today that the European ... Pay-Per-View - PR Newswire - HighBeam Research

Brand Names/Synonyms:
Zaleplon is also known by the following brand names and/or synonymsCHEMBANK1807; Dea No. 2781; L846; Sonata; ZAL 846; Zalaplon; Zaleplon; Zaleplon [Usan:Inn]

Drug Category:
Zaleplon is categorized under the following by the FDA: Hypnotics and Sedatives; Anticonvulsants; Anxiolytics sedatives and hypnotics; ATC:N05CF03

Dosage Forms:
CAPSULE

Absorption:
Absorption Zaleplon is rapidly and almost completely absorbed following oral administration.

Interactions:
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Chemical IUPAC Name:
N-[3-(9-cyano-2,6,7-triazabicyclo[4.3.0]nona-2,4,7,9-tetraen-5-yl)phenyl]-N-ethyl-ethanamide





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