Zetia

This page contains recent news articles, when available, and an overview of Zetia but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Zetia
(when available)

Pharmacology and use:
Ezetimibe is in a class of lipid-lowering compounds that selectively inhibits the intestinal absorption of cholesterol and related phytosterols. Ezetimibe, administered alone is indicated as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors. Ezetimibe has a mechanism of action that differs from those of other classes of cholesterol-reducing compounds (HMG-CoA reductase inhibitors, bile acid sequestrants, fibric acid derivatives, and plant stanols). Ezetimibe does not inhibit cholesterol synthesis in the liver, or increase bile acid excretion but instead localizes and appears to act at the brush border of the small intestine and inhibits the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver. This causes a reduction of hepatic cholesterol stores and an increase in clearance of cholesterol from the blood; this distinct mechanism is complementary to that of HMG-CoA reductase inhibitors. For use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia.

Mechanism Of Action:
Ezetimibe localizes and appears to act at the brush border of the small intestine and inhibits the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.

News Articles on Ezetimibe

FDA panel says Vytorin and Zetia probably don't cause cancer  -  ‎Dec 24, 2009‎
A comprehensive review of previous studies involving the cholesterol-lowering drugs Vytorin and Zetia and two large ongoing studies shows that "it is ... Los Angeles Times (blog)

FDA Review of Vytorin Deems Cancer Risk “Unlikelyâ€?  -  ‎Dec 28, 2009‎
...s Vytorin, a popular cholesterol medication that combines Zocor (simvastatin) with Zetia (ezetimibe), does not necessarily raise the risk of cancer or ... DrugWatch.com

Business Highlights  -  ‎Dec 22, 2009‎
Vytorin, a top moneymaker for Merck, combines two types of brand-name cholesterol pills, Zetia and Zocor, which is available as an inexpensive generic drug. ... The Associated Press

Niacin may be effective in lowering cholesterol  -  ‎Dec 18, 2009‎
A: In a November study in the New England Journal of Medicine, niacin was compared with ezetimibe (Zetia), one part of the combination medicine Vytorin. ... Los Angeles Times

ARBITER leaves some lasting marks on Merck  -  ‎Dec 21, 2009‎
The study showed that Abbott Labs' Niaspan, an extended-release niacin, bested ezetimibe—an ingredient in Merck's cholesterol-lowering drugs Zetia and ... Medical Marketing and Media

Briefs: American attendants union appoints 2 strike administrators  -  ‎Dec 22, 2009‎
Bloomberg News Merck's cholesterol pills Vytorin and Zetia are unlikely to raise the risk of cancer, though an association can't be ruled out, US regulators ... Fort Worth Star Telegram

Glenmark may settle with Merck on cholesterol drug  -  ‎Dec 14, 2009‎
Merck sells this drug under the brand name Zetia. Patent issues: Tablets of Merck's anti-cholesterol drug Zetia. A Glenmark spokesperson declined comment ... Livemint

Merck spent $1.5M in 3Q lobbying on health reform  -  ‎Dec 23, 2009‎
...the maker of asthma and allergy drug Singulair, diabetes pill Januvia and cholesterol pills Vytorin and Zetia spent lobbying in the year-ago period. ... The Associated Press

4 Troubling Trends in Comparative Effectiveness Research  -  ‎Dec 13, 2009‎
...after 7 years on the market and raking in $3.5 billion, Merck's cholesterol-lowering medication Zetia has been shown to be ineffective. ... Ethiopian Review

Pharma sought safe havens for DTC in '09  -  ‎Dec 31, 2009‎
Merck also reduced spend by nearly 17%, the nine-month data show, reflecting decreased outlay behind its cardio franchise (Vytorin and Zetia) and the HPV ... Medical Marketing and Media

Business briefs: Houston firm may buy SunCruz Casinos ships  -  ‎Dec 23, 2009‎
Vytorin, a top moneymaker for Merck, combines two types of brand-name cholesterol pills, Zetia and Zocor, which is available as an inexpensive generic drug. ... Florida Times-Union

The World's Largest M&A Deals in 2009 (PFE, WLA, GM, SGP, MRK)  -  ‎Dec 28, 2009‎
...uniting the makers of cholesterol drugs Zetia and Vytorin in the second megadeal in the global pharmaceutical industry during the year. ... Benzinga

How soy affects the body  -  ‎Dec 20, 2009‎
Thyroid: Some believe that the excessive consumption of soy foods and supplements can cause hypothyroidism. Those in the pro-soy camp believe it only ... Chicago Tribune

Merck  -  ‎Dec 22, 2009‎
Merck's (MRK) cholesterol drugs Vytorin and Zetia probably don't raise cancer risks, but a link can't be ruled out completely, the FDA said Tuesday. ... Investor's Business Daily

FDA:Vytorinä¸?太å?¯èƒ½æœƒå¢žåŠ ç™Œç—‡é¢¨éšª  -  ‎Dec 30, 2009‎
Vytorinçµ?å?ˆå…©ç¨®é™?膽固醇藥物,一種是默克藥廠的Zocorï¼›å?¦ä¸€ç¨®æ˜¯é»˜å…‹å’ŒSchering-Plough生產的Zetia。 FDA在2008å¹´8月表示,有份臨床試驗調查報告èª?為,Vytorin和癌症 ... 臺灣新浪網

FDA, "머í?¬ 'ë°”ì?´í† ë¦°' ì•” 유발하지 않아"  -  ‎Dec 22, 2009‎
...ë°”ì?´í† ë¦°ì?€ 머í?¬ì?˜ '제티아(Zetia)'와 'ì¡°ì½”(Zocor)'를 복합한 콜레스테롤 약물. 제티아와 ë°”ì?´í† ë¦°ì?€ 최고 매출ì?´ 50ì–µ 달러ì—? 달하기ë?„ 했었다. ... 데일리팜

Bệnh cao mỡ trong máu – phần 2  -  ‎Dec 24, 2009‎
Ngoài ra, cÅ©ng có những loại tuy nó không làm cho gan bị sưng nhưng nó rất yếu thí dụ những loại thuốc như Zetia, hoặc là những loại để chữa phụ thêm như ... Đài Á Châu Tự Do

Merck & Co: US-Gesundheitsbehörde FDA gibt Entwarnung  -  ‎Dec 22, 2009‎
Die US-Gesundheitsbehörde FDA hat teilweise Entwarnung für die beiden Cholesterinsenker Vytorin und Zetia des Pharmakonzerns gegeben. ... Aktien Meldungen

MORNING BRIEFING - Märkte (USA/Asien)  -  ‎Dec 22, 2009‎
Die FDA hat teilweise Entwarnung für die beiden Cholesterinsenker "Vytorin" und "Zetia" gegeben. Es sei "unwahrscheinlich", dass die Mittel das Risiko einer ... Der Aktionär

A New Cholesterol Study Puts Focus on Merck Drugs  -  ‎Nov 12, 2009‎
At stake are sales of Vytorin and Zetia, two cholesterol-lowering drugs that, even with the coming study factored in, are projected to bring in $4.5 billion ... New York Times

US EQUITIES WEEK AHEAD: Retailers, GM Report; Inflation Data  -  ‎Nov 13, 2009‎
Results of a clinical trial comparing cholesterol drugs Zetia from Merck & Co. (MRK) and Niaspan from Abbott Laboratories (ABT) will be presented Monday ... CNNMoney.com

Merck Cholesterol Pill Sales May Drop 20% After Study  -  ‎Nov 10, 2009‎
10 (Bloomberg) -- Merck & Co. may face a third negative study result within two years for its cholesterol pills Vytorin and Zetia, which have lost 14 ... Bloomberg

Amateur Hour at Merck: FDA Refuses to Look at Zetia-Lipitor Combo Pill  -  ‎Nov 4, 2009‎
Merck was sent back to the drawing board on its new Zetia-Lipitor combo drug when the FDA refused to accept its application. ... BNET

The Next Vytorin Study: Why Is Everybody So Worked Up?  -  ‎Nov 13, 2009‎
Vytorin is actually a combination of two cholesterol drugs — the generic simvastatin and the patent-protected Zetia. Zetia and Vytorin are a huge franchise, ... Wall Street Journal (blog)

Merck 3Q Net More Than Triples On Gain; Boosts View  -  ‎Oct 22, 2009‎
Merck reported combined sales of cholesterol drugs Vytorin and Zetia of $1 billion, down 7% from a year earlier. Schering-Plough reported slightly different ... Wall Street Journal

If You've Taken Zetia or Vytorin, There Might Be $$ Headed Your Way  -  ‎Nov 4, 2009‎
If you bought Vytorin® and/or Zetia® to lower your cholesterol between November 1, 2002, and September 17, 2009, you may be entitled to some money. ... Diabetes Health (press release)

Zetia and Vytorin purchasers eligible for piece of $41.5 million lawsuit ...  -  ‎Oct 26, 2009‎
The lawsuit is called In re Vytorin/Zetia Marketing, Sales Practices, and Products Liability Litigation. The lawsuit claims that the defendants violated ... newjerseynewsroom.com

Heart valve changes don't always warrant treatment  -  ‎Nov 3, 2009‎
Dear Dr. Donohue: I take Zetia every day, and I have read and heard that it is not good. A friend told me her doctor indicated it could cause cancer. ... Herald & Review

$41.5 Million Settlement Okayed in Ezetimibe Suit  -  ‎Oct 23, 2009‎
The settlement approved today covers "consumers and insurance companies or other entities that paid for or provided reimbursement for either Zetia or ... MedPage Today

Wall Street Firm Believes Risks are Priced into Merck Shares (MRK)  -  ‎Nov 9, 2009‎
The company suggests another possible leg down for Zetia/Vytorin in the US, but believes the current valuation already implies the loss of more than 50% of ... Dividend.com (blog)

Spectrum inks $151M Asian pact; Dynavax strikes deal to acquire Symphony Dynamo;  -  ‎Nov 10, 2009‎
That's when researchers will unveil the latest trial of Merck's cholesterol meds Vytorin and Zetia. Report > It looks as if yet another US drug-marketing ... FierceBiotech

Merck & Co earnings climb as Januvia and Isentress impress  -  ‎Oct 23, 2009‎
Pharmaceutical revenues were flat at $3.50 billion, amid declining sales from its cholesterol joint venture with Merck for Vytorin and Zetia (see above). ... Pharma Times

US stock market opening report (November 13, 2009, Friday)  -  ‎Nov 13, 2009‎
...of the American Heart Association with potentially significant implications for Zetia and Vytorin, multibillion dollar cholesterol medications from co. ... Stock Markets Review

Drug stocks wrap around flat line; Amgen falls on drug delay  -  ‎Oct 22, 2009‎
Merck also reported that sales of the cholesterol drugs Vytorin and Zetia fell 7% to $1 billion for the latest three months. ... MarketWatch

Business Highlights  -  ‎Nov 2, 2009‎
...of Pfizer Inc.'s Lipitor — which generates nearly $13 billion in annual sales — and Zetia, a cholesterol pill Merck sells with Schering-Plough Corp. ... The Associated Press

Merck Announces Third-Quarter 2009 Financial Results  -  ‎Oct 22, 2009‎
Global sales of ZETIA, marketed as EZETROL outside the United States, were $514 million in the third quarter, a decrease of 4 percent compared with the ... Reuters

Business Briefs: Stanley Works to buy Black & Decker for $4.5B  -  ‎Nov 2, 2009‎
...of Pfizer Inc.'s Lipitor — which generates nearly $13 billion in annual sales — and Zetia, a cholesterol pill Merck sells with Schering-Plough Corp. ... NewsOK.com

Schering-Plough Reports Financial Results for 2009 Third Quarter  -  ‎Oct 22, 2009‎
ZETIA in Japan, sold under a co-marketing agreement with Bayer, contributed $47 million to cholesterol franchise sales in the 2009 period. ... Reuters

J&J restructuring claims up to 8000 jobs; Rigel pushes failed drug into Phase ...  -  ‎Nov 3, 2009‎
Story > The FDA has rejected Merck's application to market a new cholesterol drug that combines Pfizer's Lipitor with Zetia. Regulators are seeking more ... FierceBiotech

Imaging study shows plaque regression with niacin vs placebo  -  ‎Oct 30, 2009‎
ARBITER-HALTS 6 is an imaging study comparing changes in carotid intima-media thickness in patients treated with ezetimibe (Zetia, Merck/Schering-Plough) or ... TheHeart.Org

3 strong economic reports lift recovery hopes  -  ‎Nov 3, 2009‎
...of Pfizer Inc.'s Lipitor - which generates nearly $13 billion in annual sales - and Zetia, a cholesterol pill Merck sells with Schering-Plough Corp. ... San Luis Obispo Tribune

One-time gains boost AstraZeneca's 3Q  -  ‎Oct 29, 2009‎
The negative ENHANCE trial results should propel Crestor sales as doctors look for an alternative to cholesterol-lowering drugs Vytorin and Zetia. 1. ... Hemscott

Judge refuses secondhand smoke testimony in South Dakota smoking ban lawsuit  -  ‎Nov 3, 2009‎
South East and London, South East and London: .. http://bit.ly/1jsruA #Jobs VerveHealth Verve Health FDA rejects Lipitor/Zetia combo drug application: The ... Gaea Times

Comenzó la operación conjunta de Merck y Schering-Plough  -  ‎Nov 4, 2009‎
Merck y Schering-Plough han sido socios desde hace varios años en la producción de los fármacos contra el colesterol Vytorin y Zetia, aunque esas ventas han ... Dinero (Colombia)

Merck geht gestärkt in Mega-Fusion mit Schering-Plough  -  ‎Oct 22, 2009‎
Mit den Cholesterin-Mitteln Vytorin und Zetia nahm Merck insgesamt 1,0 Milliarden Dollar ein und damit sieben Prozent weniger als vor einem Jahr. ... Reuters Deutschland (Pressemitteilung)

FDA, '리피토+제티아' 승ì?¸ì‹ ì²­ ê±°ë¶€  -  ‎Nov 2, 2009‎
...í™”ì?´ìž?ì?˜ 고지혈ì¦?약 '리피토'(Lipitor)와 머í?¬ì™€ ì‰?ë§?-푸ë?¼ìš°ì?˜ 콜레스테롤 저하제 '제티아(Zetia)' 복합제가 FDA로부터 승ì?¸ì‹ ì²­ ìž?체를 거부당했다. ... 메디파나뉴스

FDA סרב ל×?שר תרופה של מרק לכולסטרול  -  ‎Nov 2, 2009‎
...החברה דיווחה לפני שנתיי×? וחצי על תכניותיה לייצר ולשווק ×?ת הקומבינציה של הליפיטור ×¢×? ×”-Zetia שלה ושל שרינג פל×?ו. בספטמבר מרק הגישה בקשה לתרופת ×”'קומבו'. ... כלכליסט

스타틴+니아스íŒ?, ê²½ë?™ë§¥ 플ë?¼í?¬ ê°?소  -  ‎Nov 2, 2009‎
...ì?´ì™€ 관련, 머í?¬ëŠ” 최근 FDAì—? '제티아'(Zetia, ezetimibe)와 '리피토'(Lipitor, atorvastatin) 복합제ì?˜ 승ì?¸ì‹ ì²­ì?„ 제출했으나 추가ì ?ì?¸ 제조 ë°? 안정성 ë?°ì?´í„°ê°€ ... 디지틀보사

Pharma news  -  ‎Oct 27, 2009‎
La fusione segue anni di collaborazione fra le due società, che insieme commercializzano farmaci blockbuster anticolesterolo come Vytorin e Zetia. ... Pharma Marketing

Das Kosovo feiert seinen Retter: Große Ehre für Bill Clinton  -  ‎Nov 1, 2009‎
Trotz guter Umsätze meinte Flaggenverkäufer Zetia Lepahtica: "Für Clinton hätte man mindestens ein zehn Meter großes Monument errichten und alle Straßen mit ... WELT ONLINE

FTD: McDonald's steigert Gewinn  -  ‎Oct 22, 2009‎
Das Asthma-Mittel Singulair erwirtschaftete hiervon 1,1 Mrd. $, mit den Cholesterin-Mitteln Vytorin und Zetia nahm Merck insgesamt eine Mrd. $ ein. ... Finanztreff

Journal warns cholesterol drugs Vytorin and Zetia may not work  -  Mar 31, 2008
By Alex Berenson. CHICAGO — Two widely prescribed cholesterol-lowering drugs, Vytorin and Zetia, may not work and should be used only as a last resort, ... New York Times

Cholesterol Drug Zetia Doesn't Cut Heart Attack Risk: Study  -  Jan 14, 2008
By Ed Edelson. MONDAY, Jan. 14 (HealthDay News)-- The long-awaited results of a trial of Zetia, a cholesterol-lowering drug prescribed to about a million ... Washington Post

DRUG GIANTS PROFIT FROM PARTNERSHIP MERCK, SCHERING TOP …  -  Oct 25, 2005
Both companies are relying on Vytorin, which includes Zetia, the first of a new ... Global sales for the Merck/Schering-Plough partnership from Zetia and ... Pay-Per-View - South Florida Sun - Sentinel - ProQuest Archiver

Data About Zetia Risks Was Not Fully Revealed  -  Dec 21, 2007
Schering and Merck — which are on track to earn $5 billion this year from sales of Zetia — had already been criticized for not promptly releasing results of ... New York Times

Zetia - Cholesterol Drugs - Merck - Schering-Plough - Clinical Trials...  -  Dec 12, 2007
By ALEX BERENSON. A Congressional committee is investigating Merck and Schering-Plough for their handling of a critical clinical trial of Zetia, ... New York Times

Zetia - Cholesterol - Drug Trials - Heart - Medicine and Health - New...  -  Jan 22, 2008
By TARA PARKER-POPE. The cholesterol drug Vytorin became known for its commercials showing people who look oddly similar to foods like tacos and banana ... New York Times

A Backlash Against Vytorin?  -  Mar 30, 2008
The vast majority expected use of Zetia and Vytorin would decline following the ... Zetia is approved for lowering cholesterol, but there is no evidence it ... Forbes

RPT Schering-Plough, Bayer get Japan OK for Zetia  -  Apr 19, 2007
FRANKFURT (Thomson Financial) - Drug maker Schering-Plough (nyse: SGP - news - people ) Inc. on Wednesday said it received Japanese marketing approval for ... Forbes

Schering-Plough CEO eyes Vytorin, Zetia rebound  -  Apr 23, 2008
NEW YORK, April 23 (Reuters) - Schering-Plough Corp's (SGP.N) Chief Executive Fred Hassan on Wednesday predicted a rebound for two company cholesterol ... Reuters UK

Cholesterol-Lowering Zetia Also Works in Liver  -  Jun 14, 2007
THURSDAY, June 14 (HealthDay News) -- Research in mice is giving new insight into how the drug ezetimibe (brand name Zetia) works to lower cholesterol. ... Washington Post

How Low Can Vytorin Go?  -  Apr 4, 2008
He used to give Zetia to those at high risk for heart attacks who ... In January, new data was released about the drug that showed while Zetia lowers LDL, ... Forbes

Schering-Plough Net Rises Fivefold on Vytorin, Zetia  -  Oct 20, 2006
By Shannon Pettypiece. Oct. 20 (Bloomberg) -- Schering-Plough Corp.'s third-quarter earnings jumped almost fivefold on higher demand for the company's ... Bloomberg

Merck quarterly results exceed outlook; 2006 estimate lifted - …  -  Jul 24, 2006
Merck's cholesterol-drug franchise for Zetia and Vytorin, ... Vytorin, a combination of Zetia and Zocor, had sales of $497 million, while Zetia saw sales ... MarketWatch

Key Vytorin Results Expected  -  Jul 21, 2008
The big debate about the drug is whether lowering cholesterol with Zetia is as good as ... The statins affect the body's production of cholesterol; Zetia is ... Forbes

Drop in Vytorin, Zetia use hits Schering stock  -  Dec 18, 2008
By Lewis Krauskopf and Ransdell Pierson. NEW YORK (Reuters) - Total US prescriptions for Schering-Plough Corp (SGP.N) and Merck & Co Inc's (MRK. ... Reuters

Merck, Schering to develop combo pill with Lipitor  -  Mar 26, 2007
Schering-Plough and Merck already have a joint venture to market Zetia and Vytorin, ... Zetia, known generically as ezetimibe, blocks absorption in the ... Reuters

Vytorin study confuses patients - Heart health- msnbc.com  -  Jan 18, 2008
Confused, patients around the country taking Vytorin or Zetia called and ... Zetia, in a different drug class, is only proven to cut bad cholesterol. ... msnbc.com

… on Increased Sales; Demand for cholesterol drugs Vytorin and Zetia...  -  Apr 21, 2006
Demand was especially strong for the cholesterol drugs Vytorin and Zetia, which the company co-markets as part of a joint venture with Merck. ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Schering-Plough Marred by Costs  -  Jul 21, 2005
The company also reported strong results for its Zetia cholesterol pill that it ... Schering-Plough doesn't include sales from its Zetia/Vytorin joint ... TheStreet.com - TheStreet.com (subscription)

Vytorin is better than Crestor, says study - Jun. 19, 2006  -  Jun 19, 2006
In this study, patients who took the Crestor-Zetia combination reduced their ... Merck and Schering-Plough produce and market Vytorin and Zetia through a ... CNNMoney.com

Schering-Plough's Zetia now in Japan  -  Jun 8, 2007
KENILWORTH, NJ, June 8 (UPI) -- Schering-Plough said Friday its cholesterol-lowering drug, Zetia, is now available in Japan. The Japanese Ministry of Health ... United Press International

Schering, Merck exceed expectations.  -  Apr 22, 2005
Combined sales of those drugs -- Vytorin and Zetia -- more than doubled to more ... "The launches of Vytorin and Zetia have gone exceedingly well so far," ... $9.94 - Knight Ridder/Tribune Business News - Alacra Store

Merck, Schering-Plough Defend Drug Study  -  Jan 25, 2008
Studies have showed Vytorin and Zetia significantly lower LDL, ... "We stand behind Vytorin and Zetia and stand behind our science," said Peter S. Kim, ... FOXNews

Merck and Schering-Plough to release findings for their cholesterol- …  -  Nov 20, 2007
NEW YORK — Prescriptions for the cholesterol-lowering drugs Zetia and Vytorin ... Cardiologists hoped the test would help them determine whether Zetia and ... New York Times

The Evidence Gap For Widely Used Drug, Question of Usefulness Is...  -  Sep 2, 2008
The lack of evidence has not stopped doctors from heavily prescribing that drug, whether in a stand-alone form sold as Zetia or as a combination medicine ... New York Times

Schering's Cholesterol Drugs Overtake Rivals  -  Jul 15, 2005
In recent months, Zetia, sold by a joint venture of Schering and Merck, ... Zetia, introduced in 2002, is usually given on top of other cholesterol drugs to ... Forbes

Schering-Plough Swings to Profit  -  Jan 30, 2006
Take) for the marketing of two cholesterol drugs, Zetia, developed by Schering-Plough, and Vytorin, a pill that combines Zetia and Merck's Zocor. ... TheStreet.com - TheStreet.com (subscription)

Schering-Plough files patent infringement action on Zetia  -  Apr 27, 2007
By Antonie Boessenkool. Schering-Plough Corp. (NYSE:MRK) said Friday it and an entity it owns jointly with Merck & Co. Inc. (NYSE:MRK) filed a patent ... MarketWatch

OK to take fish oil with Zetia, but benefit is uncertain  -  Aug 15, 2006
By Richard Harkness. I've tried to take statins (Zocor and Pravachol), but had to stop because they caused leg cramps. Now I'm taking only Zetia for ... San Diego Union - Tribune - San Diego Union Tribune

Schering-Plough 2Q profit soars  -  Jul 23, 2007
..."Seven out of our 10 largest-selling products, including Vytorin and Zetia, posted double-digit sales growth for the quarter," said Fred Hassan, ... USA Today

Statins, Zetia reverse atherosclerosis in study  -  Dec 3, 2008
By Bill Berkrot. NEW YORK, Dec 3 (Reuters) - Aggressive lowering of bad LDL cholesterol beyond current guidelines using Zetia with statins or statins alone ... Reuters

Schering-Plough's Loss Expands to $834 Million on Tax Costs  -  Jan 25, 2005
Hassan is counting on demand for the cholesterol drugs Zetia and Vytorin, a combination of Zetia and Merck & Co.'s Zocor, to help revive sales growth. ... Bloomberg

Merck's CEO Praises Progress  -  Apr 11, 2006
...up from $510.6 million a year ago. Merck helps market Schering-Plough's cholesterol drug Zetia, as well as Vytorin, a pill that combines Zetia and Zocor. TheStreet.com - TheStreet.com (subscription)

Schering-Plough profit rises on cholesterol drugs  -  Jan 29, 2007
The figure excludes Zetia and Vytorin, which are co-marketed under a joint venture with Merck ... Zetia blocks absorption by the intestines of cholesterol; ... Reuters

Cholesterol Drug Scare Shenanigans  -  Sep 4, 2008
Drug companies Merck and Schering-Plough, the makers of Zocor and Zetia, ... Drazen also was unwilling to cede that higher cancer death rate of Zetia ... FOXNews

Article: STATINS NO. 1, BUT ZETIA GOOD DRUG.(Living) - The …  -  Apr 7, 2006
STATINS NO. 1, BUT ZETIA GOOD DRUG.(Living) ... find The Cincinnati Post (Cincinnati, OH) articles. Byline: Peggy and Terry McDannold Living on a farm and ... Pay-Per-View - Cincinnati Post - HighBeam Research

Vytorin On Trial  -  Mar 21, 2008
Zetia is a unique drug for lowering cholesterol; Vytorin combines it in one ... If it turns out that Zetia doesn't prevent heart attacks in the 2011 study ... Forbes

Merck, Schering-Plough split sales on cholesterol drugs. - Jun. 20,...  -  Jun 20, 2005
Vytorin contains Zetia, a drug produced by Schering-Plough that inhibits absorption of ... Schering-Plough launched Zetia in the United States in November, ... CNNMoney.com

Drug makers' earnings climb  -  Apr 20, 2007
Combined sales of Vytorin and Zetia increased 47% to $1.2 billion, Merck said. Merck and Schering-Plough split revenue from the drugs. ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

FDA Approves New Indication for ZETIA(R) (ezetimibe) - Merck/Schering...  -  Jun 9, 2006
Merck/Schering-Plough Pharmaceuticals announced today that the US Food and Drug Administration (FDA) has approved ZETIA(R) (ezetimibe) for use, ... Free with registration - Business Wire - AccessMyLibrary.com

… gaining market share without sapping Zetia.(NEWS) - Medical...  -  Oct 1, 2005
Vytorin gaining market share without sapping Zetia.(NEWS) ... find Medical Marketing & Media articles. SINCE LAUNCHING last year, Schering-Plough's ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Schering-Plough posts $3.4B loss  -  Feb 12, 2008
Studies have shown Vytorin and Zetia significantly lower LDL, or bad cholesterol, ... Vytorin combines Schering-Plough's Zetia and Merck's Zocor. ... USA Today

Merck And Schering Backtrack  -  Dec 11, 2007
Merck and Schering-Plough are backtracking on plans to change an important clinical trial testing the efficacy of the blockbuster cholesterol drugs Zetia ... Forbes

Efficacy Questions Still Dog Vytorin  -  Aug 27, 2008
Roger Blumenthal has been a defender of the cholesterol drugs Zetia and Vytorin. ... Blumenthal thinks Zetia is still a good option for people who need high ... Forbes

Cost controls help Merck beat profit forecast  -  Apr 21, 2008
Combined sales of cholesterol drugs Vytorin and Zetia rose 6 percent in the ... The combination drug and Zetia are sold through a 50/50 joint venture of ... Reuters

Vytorin's Cancer Question  -  Sep 2, 2008
Peto lumped together data from two ongoing studies, SHARP and IMPROVE-IT, and found 97 cancer deaths on Zetia vs. 72 on placebo or Zocor. ... Forbes

Reasons to Believe in Schering-Plough  -  Feb 11, 2008
Despite the recent controversy, analysts expect Zetia and Vytorin, sold via a joint venture ... Vytorin combines Schering-Plough's Zetia with Merck's Zocor. ... TheStreet.com - TheStreet.com (subscription)

Vytorin gaining market share without sapping Zetia.(NEWS)  -  Oct 1, 2005
SINCE LAUNCHING last year, Schering-Plough's dual-action cholesterol-lowering product Vytorin has risen to sixth among the top nine lipid-lowering drugs, ... Free with registration - Medical Marketing & Media - AccessMyLibrary.com

Schering-Plough, Merck shares keep clawing back  -  Apr 7, 2008
Rubin noted that the decline in new Vytorin and Zetia prescriptions last week was significantly less pronounced than the decline in the first week after the ... Reuters

Article: Results on cholesterol drug's risks said to be withheld - …  -  Dec 22, 2007
Article: Data about Zetia risks was not fully revealed by Merck and ... ... 21 ... raise questions about whether Zetia can cause liver damage when ... the ... Pay-Per-View - International Herald Tribune - HighBeam Research

Dems Question Timing of Vytorin Papers  -  Apr 11, 2008
Schering said it would cut $1 billion in annual costs by 2012 and slash 10 percent of its staff amid wide expectations that sales of Vytorin and Zetia will ... FOXNews

Merck posts loss on Vioxx charges, shares fall  -  Jan 31, 2008
The results sparked questions about whether the cost of Vytorin and its sister drug Zetia were justified. Combined quarterly sales of Vytorin and Zetia grew ... Reuters India

Merck posts 4th-quarter loss on charges tied to Vioxx settlement - …  -  Jan 30, 2008
Combined sales of popular cholesterol drugs Vytorin and Zetia shot up 34% to $1.5 billion. The products are marketed and accounted for under the equity ... MarketWatch

Cholesterol drug study renews questions - Heart health - MSNBC.com  -  Mar 31, 2008
Full results of a trial of Vytorin and one of its components, Zetia, ... Bonow cautioned that patients who are taking Vytorin or Zetia might have been ... msnbc.com

Vytorin, Zetia should be drugs of last resort, panel urges  -  Mar 31, 2008
CHICAGO -- The blockbuster drugs Vytorin and Zetia should be used only after all other cholesterol-lowering drugs fail until research proves that the ... Pay-Per-View - USA TODAY - ProQuest Archiver

Article: Drug test results: Too little too late? - International...  -  Nov 21, 2007
Prescriptions for the cholesterol-lowering drugs Zetia and Vytorin are written for ... Article: Data about Zetia risks was not fully revealed by Merck and . ... Pay-Per-View - International Herald Tribune - HighBeam Research

Vytorin Makers Get Subpoenas As Handling of Trial Is Probed  -  Jan 28, 2008
The companies co-market Vytorin and its sister drug, Zetia, as a joint venture. ... During that time, combined annual sales of Vytorin and Zetia grew to ... Wall Street Journal

Merck cuts 7200 jobs as earnings sag  -  Oct 23, 2008
Fresh trouble for Merck began in January when a study on Zetia and Vytorin ... Vytorin combines Zetia with Zocor in one pill. Merck shares the revenue from ... WA today

Schering, Merck defend cholesterol drugs in ads  -  Jan 20, 2008
Vytorin combines Zetia and Zocor, known generically as simvastatin, into one pill. Vytorin did cut levels of "bad" LDL cholesterol more than Zocor, ... Reuters UK

Nevada firm sues cholesterol drug makers  -  Feb 4, 2008
...'Vytorin and Zetia have been shown to reduce LDL cholesterol in numerous clinical studies and they have been approved by the FDA for that indication,' Merck ... Forbes

FDA Investigates Possible Vytorin-Cancer Link  -  Aug 22, 2008
It's a combination of Merck's Zocor (simvastatin), a statin, and Schering-Plough's Zetia. A report earlier this year found the drug failed to reduce the ... U.S. News & World Report

Schering-Plough CEO buys shares, keeps pledge  -  Apr 24, 2008
Schering-Plough sells Vytorin and Zetia through a joint venture with Merck. Combined sales of Vytorin and Zetia rose 6 percent to $1.2 billion during the ... Reuters

Schering-Plough 3Q Profit Falls, but Tops Forecast  -  Oct 21, 2008
That international boost is most evident in sales of the company's troubled cholesterol drug franchise, including Zetia and Vytorin. ... ABC News

Merck Earnings Rise on Vaccines, Cholesterol Drugs  -  Apr 19, 2007
Sales of the cholesterol pills Vytorin and Zetia, the asthma drug Singulair ... Combined sales of Vytorin and Zetia increased 47 percent to $1.2 billion. ... Bloomberg

Lawmakers demand study data on Vytorin cancer risk  -  Aug 21, 2008
Vytorin combines Merck's now-generic statin drug, Zocor, with a different type of cholesterol drug, Zetia, made by Schering-Plough. ... San Diego Union - Tribune - San Diego Union Tribune

Weak US dollar should boost Big Pharma earnings  -  Jul 19, 2008
A combination of Merck's popular cholesterol agent Zocor and a newer drug called Zetia, Vytorin has been regarded as a key future growth driver for both ... MarketWatch

Should Schering-Plough's Chief Give Back His Bonus?  -  May 19, 2008
ENHANCE did not show the expected benefit for Vytorin and Zetia in preventing ... If sales of Vytorin and Zetia had stalled--but not dropped--in the second ... Forbes

Survey Report: Many Doctors Stand by Ezetimibe (Zetia)  -  Apr 11, 2008
By Marianne Mattera, Managing Editor, MedPage Today. A sizeable minority of doctors continues to believe that ezetimibe (Zetia) is a powerful agent for ... MedPage Today

A cholesterol drug bombs  -  Jan 6, 2008
The drug, Zetia, and a combination pill that contains it, Vytorin, ... Meanwhile, it seems clear that Zetia and Vytorin should be used sparingly, ... New York Times

Investors Cheer Schering-Plouch  -  Apr 19, 2007
Hassan has staked his company's success on Zetia, which prevents absorption of cholesterol in the intestine, as well Vytorin, which blends Zetia with ... BusinessWeek

Article: Study casts doubts on value of cholesterol drug - Internation...  -  Jan 16, 2008
Merck and Schering-Plough, which make the drug, Zetia, and a pill that contains it, ... Expanded Indication for ZETIA Offers a New Treatment Alternative . ... Pay-Per-View - International Herald Tribune - HighBeam Research

Drugs that don't work: tough pill to swallow - Health care - MSNBC.com  -  Apr 4, 2008
And now they've seen the results on Vytorin and Zetia, which account for more than 15 percent of the cholesterol-lowering drug market in the US — and more ... msnbc.com

… Combination Treatment With AEGR-733 And Zetia(R) Reduces LDL …  -  Nov 16, 2006
Patients treated with Zetia(R) alone achieved a 20% reduction in LDL cholesterol. There was no difference in discontinuation rates between the patients ... Medical News Today - Medical News Today (press release)

Inside Schering And Merck's Secret Panel  -  Jan 11, 2008
ENHANCE, as the study is known, tests whether the cholesterol drugs Zetia and Vytorin, which together generate $5 billion annually, do a better job than a ... Forbes

Schering-Plough, Merck Profit to Rise on Combo Pill  -  Jul 20, 2007
The pill, which combines Zocor with Zetia, is sold jointly by Merck and Schering ... The drug is priced in line with Zocor, and costs less than Zetia and ... Bloomberg

The Statin Showdown  -  Jun 30, 2008
Vytorin gets extra cholesterol-lowering oomph by combining Zocor with a newer drug, Zetia. But Liao argues that Zetia might actually make this inflammation ... Forbes

Cardiologists Question Delay of Data on 2 Drugs  -  Nov 21, 2007
Prescriptions for the cholesterol-lowering drugs Zetia and Vytorin are written ... Unlike the other medicines, called statins, Zetia has not yet been proven ... New York Times

Article: Doubts assail 2 anti-cholesterol drugs Schering-Plough and...  -  Apr 1, 2008
Vytorin and Zetia are among the top-selling drugs in the world, ... Merck and Schering-Plough, which make Vytorin and Zetia, said Sunday that they disagreed ... Pay-Per-View - International Herald Tribune - HighBeam Research

Zetia and Zocor: Good together?  -  Feb 1, 2005
It seems as if they keep moving the "bad" LDL cholesterol goal line so it's harder to reach. Health guidelines say your LDL level should be 100 mg/dL or ... $4.95 - Harvard Health Letter - ECNext

Vytorin, Zetia scrips drop 13 percent  -  Mar 18, 2008
This doesn't look much like a rebound to us. It's more like a bounce downhill. Vytorin and Zetia prescriptions dropped 13 percent in February, ... FiercePharma

Schering-Plough shares higher on analyst report  -  May 14, 2008
2010 because of prescription trends for the company's cholesterol drugs, Vytorin and Zetia, that are more favorable than the firm earlier forecast. ... Boston Globe

Dems Question Timing of Vytorin Papers  -  Apr 15, 2008
Schering said it would cut $1 billion in annual costs by 2012 and slash 10 percent of its staff amid wide expectations that sales of Vytorin and Zetia will ... Seattle Times

… no benefits for patients taking cholesterol drug Zetia.(Front) |...  -  Jan 15, 2008
Trial finds no benefits for patients taking cholesterol drug Zetia.(Front) ... find The Virginian Pilot articles. Byline: ALEX BERENSON By Alex Berenson The ... Pay-Per-View - Virginian-Pilot - HighBeam Research

Merck shares surge in pharma turnaround  -  Jul 25, 2007
Merck and Schering-Plough have a joint venture to sell Vytorin and Zetia. ... Sales of Vytorin and Zetia increased 30 per cent to $US1.2 billion in the ... The Australian

Schering-Plough Announces ZETIA Approved in Japan for Treatment of …  -  Apr 18, 2007
KENILWORTH, NJ, April 18 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP) today announced that Schering-Plough KK, the company's country ... Genetic Engineering News - Genetic Engineering News (press release)

Pfizer's Drug Problem: Lipitor  -  Jun 14, 2007
Schering-Plough's (SGP - commentary - Cramer's Take) Zetia has 8.2% of total ... Vytorin, which combines Zetia and Zocor, is up to 10.9% from 9.5%. ... TheStreet.com - TheStreet.com (subscription)

Trial Results for the Cholesterol Blocker Zetia Have Not Been Revealed  -  Feb 15, 2008
...(NaturalNews) Has your doctor prescribed Zetia or the combination drug Vytorin to you to lower your total cholesterol or your LDL cholesterol? ... Natural News.com

A new study raises fresh concerns about Zetia and its cousin,...  -  May 22, 2008
In this May 22, 2008 file photo, the company logo is seen on the doors of a building at Merck & Co. headquarters in Whitehouse Station, NJ ... Gainesville Sun

Vytorin and Zetia fail in heart study | Article from Deseret News...  -  Mar 31, 2008
Vytorin and Zetia fail in heart study ... find Deseret News (Salt Lake City) articles. CHICAGO -- Leading doctors urged a return to older, tried-and- true ... Pay-Per-View - Deseret News - HighBeam Research

NJ doctors favor older cholesterol pills | Article from The Record...  -  Apr 1, 2008
The trial suggested that the drugs, Zetia and Vytorin, did not slow the ... Statins block the liver from producing cholesterol, while Zetia stops the ... Pay-Per-View - The Record - HighBeam Research

Schering-Plough's Shares Fall After Earnings Miss  -  Oct 22, 2007
Analysts said prescriptions for the cholesterol drugs Zetia and Vytorin, ... Global joint- venture revenue, which includes sales of Vytorin and Zetia, ... Bloomberg

Delays in drug's test fuel wider data debate  -  Mar 25, 2008
Zetia, introduced in 2002, and Vytorin, in 2004, are both approved by the Food ... But the companies haven't proved that Zetia contributes any heart-attack ... Livemint

Data About Zetia Risks Was Not Fully Revealed  -  Jan 1, 2008
New evidence shows that the drug makers Merck and Schering-Plough have conducted several studies of their popular cholesterol medicine Zetia that raise ... Diabetes In Control

Drug Doesn't Slow Artery Clogs, Study Says; Finding Indicates Vytorin...  -  Jan 15, 2008
Zetia was approved in 2002, and Vytorin was approved in 2004. ... Previous studies have shown Zetia and Vytorin are effective at lowering cholesterol, ... Pay-Per-View - Washington Post - HighBeam Research

Schering-Plough sees cholesterol drug sales rising  -  Dec 27, 2007
N) said on Thursday that it expects to report higher sales of its cholesterol drugs Vytorin and Zetia in the fourth quarter of 2007 and in 2008 even though ... Reuters

The Vytorin Hangover  -  Dec 8, 2008
For Merck and Schering-Plough, it is the $5 billion question: Does Zetia ... Vytorin is a combo pill of Zetia and Zocor, and is sold by Merck (nyse: MRK ... Forbes

PEOPLE'S PHARMACY  -  Feb 23, 2007
I have been taking Zetia for four months with impressive results. ... Zetia (ezetimibe) works differently from statin drugs such as Lipitor or Zocor. ... Pay-Per-View - The Sun - ProQuest Archiver

Zetia, with fenofibrate, approved.(PRODUCTS)(Brief article)  -  Oct 15, 2006
Zetia (ezetimibe) has received an expanded approval in combination with diet ... In the pivotal study, Zetia 10 mg was administered with 160 mg fenofibrate. ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Vytorin/Zetia  -  Jan 15, 2008
Many people take medication for high cholesterol. But now a new study says a popular drug may not have a major medical benefit when it comes to preventing ... WHDH-TV

Canadian Doctors Cautious On Cholesterol Drug  -  Mar 31, 2008
It's an active ingredient in two products, Zetia and Vytorin. ... SILBERNER: Canada didn't approve Zetia until seven months after the US and it still hasn't ... NPR

Brand Names/Synonyms:
Zetia is also known by the following brand names and/or synonymsEzedoc; Ezetimibe; Ezetimibe [Usan:Inn]; Ezetimibe [Usan]; Vytorin; Zetia

Drug Category:
Zetia is categorized under the following by the FDA: Anticholesteremic Agents; Cholesterol Absorption Inhibitors; ATC:C10AX09

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one





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