Ziagen

This page contains recent news articles, when available, and an overview of Ziagen but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Ziagen
(when available)

Pharmacology and use:
Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Abacavir is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated. For the treatment of HIV-1 infection, in combination with other antiretroviral agents

Mechanism Of Action:
Abacavir is a carbocyclic synthetic nucleoside analogue. Intracellularly, Abacavir is converted by cellular enzymes to the active metabolite carbovir triphosphate, an analogue of deoxyguanosine-5'-triphosphate (dGTP). Carbovir triphosphate inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.

News Articles on Abacavir

Study Identifies Viread And Emtriva As The Preferred Initial Treatment For HIV ...  -  ‎Dec 10, 2009‎
A recent study finds Viread (tenofovir) and Emtriva (emtricitabine) are more effective nucleoside reverse transcriptase inhibitors (NRTIs) than Ziagen ... The AIDS Beacon (blog)

Kudos to University of Minnesota tech transfer  -  ‎Dec 14, 2009‎
Excluding royalties from Ziagen, an anti-AIDS drug license to GlaxoSmithKline, licensing revenue rose 11 percent to $8.7 million. Admittedly, these aren't ... MedCity News

New Label For Anti-HIV Drug Lexiva Warns Of Heart Attack Risk  -  ‎Dec 10, 2009‎
Ziagen (abacavir) has also been associated with increased risk of heart problems (see related AIDS Beacon news). HIV infection itself is also associated ... The AIDS Beacon (blog)

Epzicom Associated With More Side Effects In HIV/AIDS Patients Than Truvada  -  ‎Nov 9, 2009‎
Alternatively, Epzicom is a combination therapy that contains Ziagen (abacavir) and Epivir (lamivudine). Viread and Ziagen were originally introduced to ... The AIDS Beacon (blog)

GlaxoSmithKline-Pfizer launch HIV joint venture  -  ‎Nov 4, 2009‎
ViiV's existing drugs are nucleoside reverse transcriptase inhibitors (NRTIs): Combivir, Epivir/3TC, Epzicom/Kivexa, Retrovir/AZT, Trizivir and Ziagen. ... Pharmafocus

Drug safety and your DNA  -  ‎Oct 30, 2009‎
The HIV/AIDS drug abacavir (trade name Ziagen) is used to treat HIV by helping inhibit an enzyme that helps the virus reproduce. ... Common Ground.ca

Glaxo und Pfizer gründen Joint Venture  -  ‎Nov 3, 2009‎
GSK steuert die Kombinationsmittel Combivir, Kivexa, und Trizivir sowie die Monopräparate Epivir, Telzir, Retrovir ud Ziagen bei. ... apotheke-adhoc

Study: AIDS Drug Lifts Heart Attack Risk  -  Apr 2, 2008
In the 754 patients who had heart attacks, 192 had recently taken Ziagen, also known as ... Those who took Ziagen, included in many AIDS regimens worldwide, ... FOXNews

Glaxo's HIV Drug Ziagen Tied to Heart Ills in Review  -  Aug 7, 2008
By John Lauerman. Aug. 7 (Bloomberg) -- GlaxoSmithKline Plc's HIV drug Ziagen was linked in a second study to an increased risk of heart attacks, ... Bloomberg

GlaxoSmithKline AIDS drug linked to risk of heart attack - Lancet...  -  Apr 3, 2008
PARIS (Thomson Financial) - Ziagen, one of the most widely-used AIDS drugs which is made by GlaxoSmithKline, may boost the risk of a heart attack, ... Forbes

Patient Satisfaction With Once-Daily Dosing Of HIV Fixed-Dose …  -  Jul 27, 2005
In one controlled study (CNA30021), more patients taking ZIAGEN 600mg once ... Multiple clinical trials have studied the use of EPIVIR and ZIAGEN in more ... $4.95 - PR Newswire - ECNext

US reviewing safety of Glaxo, Bristol AIDS drugs  -  Mar 27, 2008
The FDA said it was still evaluating the data on Glaxo's Ziagen and Bristol-Myers' Videx ... Patients taking either Ziagen or Videx "had a greater chance of ... Reuters

FDA Warns of HIV Drug Tampering  -  Apr 11, 2007
April 11, 2007 -- The FDA today warned that certain bottles of the HIV drug Combivir may actually contain Ziagen, another HIV drug. ... WebMD

US reviewing safety of Glaxo, Bristol AIDS drugs  -  Mar 28, 2008
The FDA said it was still evaluating the data on Glaxo's Ziagen and Bristol-Myers' Videx ... Patients taking either Ziagen or Videx "had a greater chance of ... Reuters India

Ziagen.(Drug overview)  -  Jan 22, 2007
Ziagen helps to halt the inroads of the human immunodeficiency virus (HIV). Without treatment, HIV gradually undermines the body's immune system, ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

Aurobindo gets USFDA nod for HIV drug  -  Jun 29, 2006
Abacavir sulfate oral solution is the version of Ziagen solution, an anti-HIV medication manufactured by GlaxoSmithKline. The company said the product would ... Hindu Business Line

Aurobindo gets tentative USFDA nod for AIDS drug  -  May 24, 2006
Abacavir Sulphate tablet is the version of Ziagen Tablets, an anti-HIV medication manufactured by GlaxoSmithKline. The company said its Abacavir would now ... Hindu Business Line

U's transfer problem  -  Apr 7, 2008
The anti-AIDS drug Ziagen has been good to the University of Minnesota. ... Since 1999, Ziagen, manufactured by GlaxoSmithKline, has generated $290 million ... Minneapolis Star-Tribune - Minneapolis Star Tribune

Business News Glaxo backs Russian HIV/Aids crusade  -  Sep 16, 2006
Glaxo will supply more than 90000 treatment packs of its drugs - Combivir, Epivir and Ziagen - to the Russian Government by the end of 2006. ... WalesOnline

Glaxo cuts HIV drug prices for poor countries  -  Feb 19, 2008
The most significant reduction is an almost 40 percent cut on Ziagen, a pill the World Health Organisation recommends as a first- and second-line treatment ... Reuters

GSK Reports Combivir and Ziagen Tampering  -  Apr 2, 2007
GlaxoSmithKline has issued a letter to healthcare providers and community educators regarding apparent third-party tampering that caused misbranding of ... AIDSmeds.com HIV/AIDS Treatment News

Press Release: Epidemiology Study Reports New Information on …  -  Jul 26, 2005
ZIAGEN is a nucleoside reverse transcriptase ... that confirmed the clinical benefits of ZIAGEN ... Ziagen belongs to a class of drugs known as nucleoside . ... Pay-Per-View - PR Newswire - HighBeam Research

GlaxoSmithKline, Canada issue warning on HIV drug  -  Jun 23, 2008
Any serious or unexpected adverse reactions in patients receiving Ziagen, Kivexa or Trizivir should be reported by calling GlaxoSmithKline toll-free at ... Boston Globe

Patient satisfaction with once-daily dosing of HIV fixed-dose...  -  Aug 1, 2005
In one controlled study ( CNA30021 ), more patients taking ZIAGEN 600mg once ... Multiple clinical trials have studied the use of EPIVIR and ZIAGEN in more ... i-newswire.com

Less Lipo and Better Lipids with Ziagen vs. Zerit  -  Mar 21, 2007
...by Martha Kerr. While lipid abnormalities and lipoatrophy are associated with highly active antiretroviral therapy (HAART) for HIV, the problem may be less ... AIDSmeds.com HIV/AIDS Treatment News

Press Release: Patient Satisfaction With Once-Daily Dosing Of HIV...  -  Jul 27, 2005
In one controlled study (CNA30021), more patients taking ZIAGEN 600mg once daily had severe ... Ziagen belongs to a class of drugs known as nucleoside . ... Pay-Per-View - PR Newswire - HighBeam Research

GSK to sell cut price HIV/Aids drugs to Russia  -  Sep 15, 2006
More than 90000 treatment packs of the anti-retroviral treatments Combivir, Epivir and Ziagen will be supplied to Russia by the end of this year. ... Hays Pharma

Ziagen, Prezista Tablets Now Available for Children  -  Dec 23, 2008
The US Food and Drug Administration (FDA) has approved children-friendly tablet formulations of two commonly used antiretrovirals: Ziagen (abacavir) and ... AIDSmeds.com HIV/AIDS Treatment News

Tentative Approval Given to New Generic Aids Drug  -  May 19, 2006
Abacavir sulfate tablets are the first generic version of the already approved Ziagen Tablets, an anti-HIV medication manufactured by GlaxoSmithKline. ... Kansas City infoZine

GSK moves to help poorest fight HIV/AIDS  -  Jun 1, 2006
Ziagen is currently recommended by the World Health Organization as a ... Differentiated packs for Ziagen tablets and Ziagen paediatric solution will be ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

Pooled-Analysis of 54 Clinical Studies Shows No Increased Risk of...  -  Aug 6, 2008
ZIAGEN, in combination with other antiretroviral agents, is indicated for the ... ZIAGEN is one of 3 medicines containing abacavir. Before starting ZIAGEN ... RedOrbit

GSK moves to help poorest fight HIV/AIDS.  -  Jun 5, 2006
Ziagen is currently recommended by the World Health Organization as a ... Differentiated packs for Ziagen tablets and Ziagen paediatric solution will be ... $9.94 - Pharma Marketletter - Alacra Store

Genetic testing can predict who is at risk of abacavir hypersensitivit...  -  Jun 8, 2006
...which is associated with a potentially life-threatening allergic reaction to the drug abacavir (Ziagen) went on to develop the hypersensitivity reaction ... Aidsmap

Brain Able to Detect Calorie Content of Food: Study  -  Mar 28, 2008
Safety reviews of Regranex Gel (becaplermin), Ziagen (abacavir) and Videx (didanosine) are being conducted by the US Food and Drug Administration, ... DentalPlans.com

Hepatitis warnings with Epivir.(be careful about abruptly stopping...  -  Apr 1, 2005
Data from study ESS30009 ... combination with once-daily Ziagen/Epivir, ... I have been on Trizivir (Retrovir, Epivir, and Ziagen)for 2 1/2 years, and ... ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

HIV therapy leads way in personalised medicine  -  Aug 2, 2007
Intriguingly, as well as indicating a strong immune response to Ziagen, this same genetic mutation has been recently shown to indicate a strong response ... DrugResearcher.com

Epidemiology study reports new information on hypersensitivity...  -  Jul 26, 2005
In one controlled study (CNA30021), more patients taking Ziagen 600 mg once daily had ... Results reported at IAS included: first exposure to Ziagen was ... Pay-Per-View - Company Reports - Factiva, from Dow Jones

Ziagen (abakavirsulfat) og overfølsomhetsreaksjoner ved gjenopptak av...  -  Oct 20, 2007
Overfølsomhetsreaksjoner med hurtig inntreden, inkludert livstruende reaksjoner har oppstått ved gjenopptak av Ziagenbehandling hos pasienter hvor ... Statens legemiddelverk

US urges genetic test before using Glaxo AIDS drug  -  Jul 24, 2008
N) drug, Ziagen, to see if they face a higher risk of a potentially fatal reaction, ... For patients who test positive for a specific gene variation, Ziagen ... Reuters UK

龙象和_产ç»?观察_è´¢ç»?纵横_新浪网  -  Dec 4, 2006
...今年7月,艾滋病è?¯ç‰©çš„主è¦?æ??供商之一葛兰素å?²å…‹åœ¨å…¶é?žç›ˆåˆ©æ€§æŠ¥ä»·å?•上新加入了两ç§?抗 艾滋病è?¯ç‰©Ziagenå’ŒTrizivir的价格,é™?幅为30%。其中Ziagen是世界å?«ç”Ÿç»„织推è??çš„ ... 新浪网

HIV/AIDS Treatment; Patients more satisfied with once-daily dosing of...  -  Aug 24, 2005
In one controlled study (CNA30021), more patients taking ZIAGEN 600mg once daily had severe hypersensitivity reactions compared to patients taking ZIAGEN ... Pay-Per-View - Vaccine Weekly - Factiva, from Dow Jones

Epzicom (abacavir + lamivudine)  -  Aug 17, 2007
Epzicom es una combinación de dos medicamentos: 600 mg de Ziagen (abacavir) y ... La marca comercial "Epzicom" es un acrónimo de EPivir y ZIagen COMbinados. ... AIDSmeds.com HIV/AIDS Treatment News

Kivexa, One Tablet Once a Day Simplifies Treatment for HIV Patients  -  Oct 26, 2005
Patient satisfaction increased when subjects were switched from a multi-drug regimen including Ziagen + 3TC twice-daily, to Kivexa once-daily within the ... DG News

Glaxo baisse le prix de ses médicaments pour les pays pauvres  -  Feb 19, 2008
La baisse de tarif la plus significative (-40%) concerne le Ziagen, un médicament que l'Organisation mondiale de la santé (OMS) préconise comme premier et ... nouvelobs.com

Calidad de vida - eluniversal.com  -  Jul 24, 2008
En los pacientes que dan positivo a una prueba sobre una variación genética específica, el tratamiento con Ziagen "no se recomienda y debería considerarse ... El Universal - El Universal (Venezuela)

Article: HONING THE EDGE: FIRST IN A CONTINUING SERIES ON …  -  Apr 6, 2008
...find Star Tribune (Minneapolis, MN) articles. Byline: THOMAS LEE; STAFF WRITER The anti-AIDS drug Ziagen has been good to the University of Minnesota. Ma... Pay-Per-View - Star Tribune - HighBeam Research

Pooled-Analysis Of 54 Clinical Studies Shows No Increased Risk Of...  -  Aug 7, 2008
ZIAGEN, in combination with other antiretroviral agents, is indicated for the ... ZIAGEN is one of 3 medicines containing abacavir. Before starting ZIAGEN ... Medical News Today - Medical News Today (press release)

HIV drug nearly doubles heart attack risk  -  Apr 7, 2008
In the 517 patients who had heart attacks, 192 had recently taken Ziagen, also known as ... Those who took Ziagen, included in many AIDS regimens worldwide, ... msnbc.com

A Punch to Gilead's Competition  -  Apr 3, 2008
Glaxo's Ziagen and its other HIV treatment, Epivir, are some of the biggest ... Sales of Ziagen by itself and in combination with other Glaxo HIV drugs in ... fool.com

Ziagen – Emplois, Effets secondaires, Interactions - Médicaments -...  -  Jun 23, 2008
Prenez votre santé en main avec notre bulletin d'information. Demeurez informé et en bonne santé! Nous recherchons des gens souffrant de pression artérielle ... Canoë

TRIZIVIR, First Tablet to Combine Three Medications for HIV, Receives...  -  May 16, 2005
TRIZIVIR is one of multiple products containing abacavir sulfate, also know as ZIAGEN. Before starting a patient on TRIZIVIR, physicians should review ... RedOrbit

Top Drug Researcher Lands at U: Her .8 Million NIH Grant Will Follow...  -  Feb 22, 2006
Nearly all of that, however, was connected to one product, the AIDS drug Ziagen. It fact, it was Ziagen money that helped seal the deal for Georg. ... RedOrbit

Trizivir.(Used to fight Human immunodeficiency virus)(Drug overview)  -  Dec 1, 2005
The abacavir (Ziagen) component of this medication which can cause a serious, ... Do not combine Trizivir with Epivir, Combivir, Retrovir, or Ziagen, ... Free with registration - PDR Family Guide to Prescription Drugs - AccessMyLibrary.com

FDA: перед применением Ziagen ® Ñ?ледует Ñ?делать генетичеÑ?кий …  -  Aug 4, 2008
24 июлÑ? 2008 г. на Ñ?айте УправлениÑ? по контролю за пищевыми продуктами и лекарÑ?твенными Ñ?редÑ?твами СШÐ? (Food and Drug Administration — FDA) поÑ?вилаÑ?ÑŒ ... Ð?птека online

DHPC over abacavir (Ziagen, Kivexa en Trizivir) en didasonine (Videx)  -  Apr 28, 2008
In vervolg op het webbericht van 2 april waarin wordt aangegeven dat een mogelijk risico bestaat op een hartaanval (myocard infarct) bij gebruik van ... Hiv Vereniging Nederland

Abacavir (Ziagen) et didanosine associés à un risque accru d'infarctus...  -  Feb 7, 2008
Il est actuellement connu que le risque cardiovasculaire des patients traités infectés par le VIH est supérieur à celui des patients infectés non traités et ... Femmes et sida

:: Agência de Notícias da Aids ::  -  Mar 28, 2008
O FDA disse que ainda está analisando os dados do fármaco Ziagen da Glaxo ... Os pacientes que tomam Ziagen ou Videx "têm mais chances de desenvolver um ... Agência de Notícias da Aids

US: Minnesota's transfer problem  -  Apr 13, 2008
The anti-AIDS drug Ziagen has been good to the University of Minnesota. ... Since 1999, Ziagen, manufactured by GlaxoSmithKline, has generated $290 million ... University World News

Revue de presse du Jeudi 3 avril 2008  -  Apr 3, 2008
Les médicaments concernés sont Ziagen® (abacavir), un médicament de ... Selon l'étude du Lancet, Ziagen doublerait le risque des patients d'avoir des ... Pharmaceutiques

Glaxo baja precios de fármacos  -  Feb 20, 2008
La disminución más importante es la de casi el 40 por ciento sobre Ziagen, una píldora que la Organización Mundial de la Salud (OMS) recomienda como ... Diario La República - COLOMBIA

Positive thinking  -  Jul 28, 2007
Among the most successful antiretrovirals now are Lamivudine, Viread and Ziagen. US infectious diseases specialist Joseph Eron says the most exciting ... The Australian

FDA Launches Safety Reviews of Three Medications  -  Mar 27, 2008
Safety reviews of Regranex Gel (becaplermin), Ziagen (abacavir) and Videx (didanosine) are being conducted by the US Food and Drug Administration, ... Washington Post

KIVEXA®, UN SÓLO COMPRIMIDO UNA VEZ AL DÃ?A SIMPLIFICA EL …  -  Mar 16, 2005
La satisfacción de los pacientes se incrementa cuando se les cambia dentro un régimen con varios medicamentos que incluye Ziagen® + Epivir® dos veces al día ... acceso.com

Weiterer wichtiger Schritt im Kampf gegen AIDS GlaxoSmithKline senkt ...  -  Jul 1, 2006
So werden die beiden Medikamente "Ziagen" und "Trizivir" rund 30 Prozent ... Ziagen-Tabletten und auch die Ziagen-Flüssiglösungen für Kinder werden in den ... presseportal.de

Trizivir (abacavir + zidovudine + lamivudine)  -  Mar 1, 2008
Trizivir no es más ni menos eficaz que Retrovir, Epivir y Ziagen tomados por separado ... de Retrovir, Epivir y Ziagen para información acerca de la posible ... AIDSmeds.com HIV/AIDS Treatment News

Epivir (lamivudine, 3TC)  -  Jun 10, 2008
Epzicom contiene Ziagen y Epivir, y debe tomarse sólo una vez al día. ... Es posible que Ziagen (abacavir) también pueda causar estos efectos secundarios. ... AIDSmeds.com HIV/AIDS Treatment News

Genetic Test 100% Effective in Screening Patients With Abacavir …  -  Jul 26, 2007
Ziagen is a registered trademark of GlaxoSmithKline, which provided funding for this study. [Presentation title: PREDICT-1: A Novel Randomised Prospective ... DG News

Press Release: Glaxo's Patent Protection on First AIDS Drug, AZT,...  -  Sep 17, 2005
Although Burroughs ... invent or discover AZT, Ziagen or 3TC, what ... Cesar Portillo of AIDS Healthcare Foundation, +1-323-860 ... ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Generic version of Glaxo HIV drug OK'd under Bush plan  -  May 18, 2006
GlaxoSmithKline's Ziagen gained FDA approval in 1998. According to GlaxoSmithKline financial reports, the drug generated $25 million in sales in 2005, ... Bizjournals.com

HIV franchise, new drugs give Gilead momentum  -  Aug 13, 2008
L) Epzicom, a combination of AIDS drugs Ziagen and Epivir. Truvada is a pill combining Gilead's Viread and Emtriva, also known as tenofovir and ... Reuters

Press Release: Glaxo's Patent Protection on First AIDS Drug, AZT,...  -  Sep 17, 2005
AIDS Healthcare Foundation (AHF ... viral prescription drugs AZT, Ziagen and 3TC and ... s about discovering AZT's ability to treat ... t invent or discover ... Pay-Per-View - PR Newswire - HighBeam Research

AIDS Treatment Remains a Delicate Balance  -  Aug 14, 2006
CAROLYN: Ziagen was one of them. I couldn't really do much of anything. ... WILSON: Certain people with HIV can't take Ziagen, and African-Americans tend to ... NPR

Article: Phony purse seller receives probation: Lake Township woman …  -  May 22, 2007
GSK has determined that counterfeit labels for Combivir tablets were placed on two bottles of Ziagen and labels on another two bottles are suspect. Both ... ... Pay-Per-View - Akron Beacon Journal - HighBeam Research

Press Release: New National Vet Pharmacy Launched: Apothepet is …  -  Jan 19, 2005
Ziagen is dosed as one 300 mg tablet twice daily for adults, ... Ziagen has been formulated as a strawberry/banana flavored liquid for use in children, ... Pay-Per-View - PR Newswire - HighBeam Research

A 'good deed' for AIDS drug hits obstacles  -  Jun 30, 2006
Glaxo, meanwhile, notes that it recently cut the price of Ziagen by 28 percent. Gilead officials admit many mistakes in conceiving their access program, ... Pittsburgh Post-Gazette - Pittsburgh Post Gazette

Press Release: TRIZIVIR, First Tablet to Combine Three Medications...  -  May 16, 2005
TRIZIVIR is one of multiple products containing abacavir sulfate, also know as ZIAGEN. Before starting a patient on TRIZIVIR, physicians should review ... Pay-Per-View - PR Newswire - HighBeam Research

Unravelling HIV treatment: Southern Africa has been bearing the brunt...  -  Apr 23, 2007
GSK's Combivir (Retrovir + Epivir), Trizivir (Retrovir + Epivir + Ziagen), the once-daily version Epivir (3TC), and Epzicom (Epivir + Ziagen) now comprise a ... Free with registration - Chemistry and Industry - AccessMyLibrary.com

Banks dominate as Footsie rises; Stocks and shares.(Business) |...  -  Apr 3, 2008
An article in the worldwide medical paper The Lancet showed that GlaxoSmithKline's anti HIV drug Ziagen may be linked to increased risk of heart attacks. ... Pay-Per-View - The Journal - HighBeam Research

U's Medical Devices Center: Incubator for invention  -  Jun 26, 2008
The U's patents on Ziagen, an anti-AIDS drug that generates 95 percent of the school's annual licensing income, will expire overseas next year and in the ... Minneapolis Star-Tribune - Minneapolis Star Tribune

GSK se implica más en la ayuda a los países más pobres del mundo en …  -  Apr 6, 2006
En la actualidad, la OMS recomienda el tratamiento con Ziagen como la opción de ... Los envases diferenciados para los comprimidos de Ziagen y la solución ... Noticias.com - Noticias.com (España)

DHHS Unveils Revised US Treatment Guidelines  -  Dec 7, 2007
To prevent this allergic reaction, the DHHS now recommends the use of this test before using either Ziagen, Epzicom or Trizivir. ... AIDSmeds.com HIV/AIDS Treatment News

U ranks high in marketing its discoveries The U's high ranking puts...  -  Sep 21, 2006
For example, Ziagen has grossed $217 million so far, making it the biggest cash cow for the U. But its revenues will drop as the exclusive patents begin ... $2.75 - Minneapolis Star-Tribune - NewsBank

What Is Phenotypic Resistance Testing?  -  Sep 6, 2007
For example, if four times as much of the NRTI Ziagen (abacavir) is needed to ... If seven times as much Ziagen is needed, the virus is sevenfold resistant ... AIDSmeds.com HIV/AIDS Treatment News

Isolated Case of Counterfeit Combivir on the Market  -  Apr 12, 2007
GlaxoSmithKline is informing health care professionals of an incident of misbranding of Ziagen (abacavir sulfate) as Combivir (lamivudine/zidovudine). ... Facts and Comparisons

Wir übernehmen Verantwortung GlaxoSmithKline seit 25 Jahren führend …  -  Nov 30, 2006
Im Mai 2006 wurden die Preise für Ziagen(R) und Trizivir(R) um 30 Prozent gesenkt. Außerdem stehen seit diesem Zeitpunkt mit Kivexa(R) und Telzir(R) zwei ... presseportal.de

VITA. Aids: la Glaxo rafforza il suo impegno per i paesi poveri  -  Jun 1, 2006
Dal primo luglio 2006 verranno infatti abbassati a livello NFP Ziagen, ... Ziagen viene attualmente raccomandato dall'Organizzazione Mondiale della Sanità ... Vita

Trizivir nel trattamento dei soggetti adulti con infezione da virus...  -  May 5, 2008
Negli studi condotti durante lo sviluppo di Ziagen, la combinazione dei tre principi attivi si è dimostrata perlomeno tanto efficace quanto i regimi ... XagenaSalute

ИÑ?Ñ?ледование журнала The Lancet: Препараты длÑ? лечениÑ? ВИЧ …  -  Apr 7, 2008
что применение Ñ?амого назначаемого антиретровируÑ?ного препарата Ziagen (abacavir) и ... кто принимает Videx, и на 89% - Ñ?реди тех, кто получает Ziagen. ... ФармацевтичеÑ?кий веÑ?тник

Abacavir Sensitivity Test Cost-Effective  -  Sep 19, 2008
Explain to interested patients that treatment with abacavir (Ziagen) can lead to severe immune reactions and even death in patients with a particular ... MedPage Today

New data reinforce efficacy of Trizivir® alone in treatment-naïve HIV...  -  Sep 28, 2006
Trizivir is one of multiple products containing abacavir sulfate, also known as Ziagen . Before starting a patient on Trizivir, physicians should review ... webwire.com

Updated HIV Treatment Guidelines Now Include Three GSK HIV …  -  Aug 13, 2006
EPZICOM contains abacavir, which is also contained in ZIAGEN(R) (abacavir sulfate) and TRIZIVIR(R) (abacavir sulfate, lamivudine, and zidovudine). ... Free with registration - PR Newswire - AccessMyLibrary.com

Head-to-Head 96-Week Study Shows EPZICOM(R) is Comparable to …  -  Aug 7, 2008
EPZICOM contains abacavir, which is also contained in ZIAGEN(R) (abacavir sulfate) and TRIZIVIR(R) (abacavir sulfate, lamivudine, and zidovudine). ... RedOrbit

Studies Disagree on Abacavir for Patients With High Viral Loads  -  Aug 12, 2008
Studies included in the analysis were CNA30021, evaluating once-daily Ziagen (abacavir), Epivir (lamivudine) and Sustiva (efavirenz); CNA30024, ... AIDSmeds.com HIV/AIDS Treatment News

Suspected abacavir hypersensitivity less likely to be diagnosed in...  -  Sep 29, 2006
People of African ethnicity have a lower reported rate of suspected hypersensivity reaction (HSR) to the nucleoside analogue, abacavir (Ziagen), ... Aidsmap

Kivexa(reg) - new one-a-day combination tablet for treatment of HIV …  -  Jan 10, 2005
Kivexa contains both the nucleosides Epivir (lamivudine) and Ziagen (abacavir) in the same daily dosage as the existing available components. ... Medical News Today - Medical News Today (press release)

GSK To Reduce Cost Of 14 Antiretrovirals Sold In Developing Nations  -  Feb 21, 2008
The company in a statement said the most significant decrease is an almost 40% price reduction of its antiretroviral Ziagen. Ziagen has been recommended by ... Medical News Today - Medical News Today (press release)

GlaxoSmithKline PLC - 3rd Quarter Results.  -  Oct 26, 2006
125 (12) 57 (15) 52 (9) 16 (5) Trizivir 63 (16) 34 (19) 27 (10) 2 (25) Epivir 46 (25) 16 (23) 21 (33) 9 (8) Ziagen 28 (12) 11 (8) 10 (23) 7 - Agenerase, ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

New Data Reinforce Efficacy of Abacavir Sulfate/Lamivudine/Zidovudine...  -  Oct 12, 2006
Trizivir is one of multiple products containing abacavir sulfate, also known as ZIAGEN. Before starting a patient on Trizivir, physicians should review ... DG News

Report says U of M does well at moving inventions to market  -  Sep 22, 2006
For example, Ziagen has grossed $217 million so far, making it the biggest cash cow for the U. But its revenues will drop as the exclusive patents begin ... $2.95 - Duluth News Tribune - NewsBank

Press Release: New Data Suggest Cymbalta(R) Reduced Pain in …  -  Aug 21, 2007
CNA30021), more patients taking ZIAGEN 600mg ... ZIAGEN BID. -- Patient satisfaction was ... Compared with patients on a regimen containing ... ... Pay-Per-View - PR Newswire - HighBeam Research

Article: Group says Wal-Mart incorrectly labeled some food products...  -  Nov 20, 2006
...bottles containing 60 tablets of Combivir (lamivudine plus zidovudine) that actually contained another medicine, Ziagen (abacavir sulfate) Tablets. ... Pay-Per-View - Food & Drink Weekly - HighBeam Research

Reyataz heart risks.(FDA Bits)(Food and drug administration)(Brief...  -  Apr 1, 2005
Fortovase Hivid Invirase Retrovir Kaletra Trizivir (Epivir + Lexiva Retrovir + Ziagen) Videx (regular or EC) Norvir Viread Reyataz Zerit Viracept Ziagen ... Pay-Per-View - HIV Treatment: ALERTS! - HighBeam Research

US regulators overturn Glaxo Aids drug monopoly. | Article from The …  -  Sep 20, 2005
Aids treatment Ziagen may have side-effects. But Glaxo said it planned to proceed with its launch of Trizivir, its new Aids drug containing Ziagen, ... Pay-Per-View - Evening Standard - HighBeam Research

Press Release: Data Show Treatment With Remicade(R) Reduced …  -  Oct 23, 2006
CNA30021), more patients taking ZIAGEN 600mg ... ZIAGEN BID. -- Patient satisfaction was ... Compared with patients on a regimen containing ... ... Pay-Per-View - PR Newswire - HighBeam Research

HIV: An ever-changing epidemic.  -  Aug 10, 2005
Similarly Epzicom, GSK's latest FDC combining Epivir with Ziagen (abacavir), ... "However Ziagen is associated with a range of side effects, ... $4.95 - M2 Presswire - ECNext

Hepatitis warnings with Epivir.(be careful about abruptly stopping...  -  Apr 1, 2005
New precautions have been added to the labeling for Epivir (3TC), Combivir (Epivir + Retrovir), Trizivir (Epivir + Ziagen + Retrovir), and Epzicom (Epivir + ... $4.95 - HIV Treatment: ALERTS! - ECNext

Press Release: JD Power and Associates Reports: Reputation Plays a …  -  Dec 19, 2005
CNA30021), more patients taking ZIAGEN 600mg ... ZIAGEN BID. -- Patient satisfaction was ... Compared with patients on a regimen containing ... ... Pay-Per-View - PR Newswire - HighBeam Research

Brand Names/Synonyms:
Ziagen is also known by the following brand names and/or synonyms1592U89; ABC; Abacavir; Abacavir [Inn]; Ziagen

Drug Category:
Ziagen is categorized under the following by the FDA: Anti-HIV Agents; Nucleoside and Nucleotide Reverse Transcriptase Inhibitors; ATC:J05AF06

Dosage Forms:
SOLUTION; TABLET

Absorption:
Rapid and extensive after oral administration (83% bioavailability)

Interactions:
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Chemical IUPAC Name:
[4-(2-amino-6-cyclopropylamino-9H-purin-9-yl)-1-cyclopent-2-enyl]methanol





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