Zocor

This page contains recent news articles, when available, and an overview of Zocor but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Zocor
(when available)

Pharmacology and use:
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. Simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B. For the treatment of hypercholesterolemia

Mechanism Of Action:
The 6-membered lactone ring of Simvastatin is hydrolyzed in vivo to generate mevinolinic acid, an active metabolite structurally similar to HMG-CoA (hydroxymethylglutaryl CoA). Once hydrolyzed, Simvastatin competes with HMG-CoA for HMG-CoA reductase, a hepatic microsomal enzyme. Interference with the activity of this enzyme reduces the quantity of mevalonic acid, a precursor of cholesterol.

News Articles on Simvastatin

FDA: Review finds no proof Vytorin causes cancer  -  ‎Dec 22, 2009‎
Merck & Co. sells Vytorin, which combines two types of cholesterol pills, Zetia and Zocor, which is available as an inexpensive generic drug. ... The Associated Press

FDA Review of Vytorin Deems Cancer Risk “Unlikelyâ€?  -  ‎Dec 28, 2009‎
...s Vytorin, a popular cholesterol medication that combines Zocor (simvastatin) with Zetia (ezetimibe), does not necessarily raise the risk of cancer or ... DrugWatch.com

SEAS: Increased cancer risk unlikely  -  ‎Dec 28, 2009‎
20 mg simvastatin or placebo; IMPROVE-IT participants are assigned to 10 mg ezetimibe plus 40 mg simvastatin or 40 mg simvastatin (Zocor, Merck) alone. ... Cardiology Today

Sector Snapshot: Statin Drug Markets ----Aarkstore Enterprise  -  ‎Dec 31, 2009‎
This snapshot also details world and US statin market sizes from 2001 through 2006, with sales figures and market share for Lipitor, Zocor, ... PRMinds (press release)

PEOPLE'S PHARMACY: Is pine bark a dangerous remedy?  -  ‎Dec 17, 2009‎
She experienced muscle pains on Zocor she was taking for cholesterol control. She discontinued it due to muscle pain and weakness. ... Tuscaloosa News

Drug major sees better China sales  -  ‎Dec 23, 2009‎
In late November, one of its best selling products named Zocor, a cholesterol-lowering medication, was included in the government's Essential Drug List, ... People's Daily Online

Drugmakers Win With Democrats' Help  -  ‎Dec 18, 2009‎
Zocor, Merk's cholesterol drug, can be bought for 77 Canadian cents versus Costco's $2.93. GlaxoSmithKline's Advair Diskus can be had for 46 Canadian ... TheStreet.com

Lilly, Kowa in promotion deal for new statin drug  -  ‎Dec 23, 2009‎
N) Zocor in patients with primary hyperlipidemia or mixed dyslipidemia, which are characterized by abnormal levels of cholesterol and fatty substances in ... Reuters

FDA panel recommends wider use for cholesterol-lowering drug Crestor  -  ‎Dec 15, 2009‎
Simvastatin (Zocor) is now sold in a generic form and the bestselling statin, Pfizer's Lipitor, will be available as a generic in 2011. ... Los Angeles Times (blog)

Business Highlights  -  ‎Dec 22, 2009‎
Vytorin, a top moneymaker for Merck, combines two types of brand-name cholesterol pills, Zetia and Zocor, which is available as an inexpensive generic drug. ... The Associated Press

The Taming of the Heart Attack  -  ‎Jan 1, 2010‎
Then simvastatin (Zocor) took off with results of the 4-S trial, which demonstrated that statin therapy reduced the risk of MI, stroke, and death. ... MedPage Today

Some Brand-Name Patents: Going, Going, Gone in 2010  -  ‎Dec 29, 2009‎
Fortunately Merck has been through it before with the loss of Zocor and more recently Fosamax. AstraZeneca's breast cancer treatment Arimidex isn't quite as ... Motley Fool

Business briefs: Houston firm may buy SunCruz Casinos ships  -  ‎Dec 23, 2009‎
Vytorin, a top moneymaker for Merck, combines two types of brand-name cholesterol pills, Zetia and Zocor, which is available as an inexpensive generic drug. ... Florida Times-Union

DotW: Last-Minute Shopping  -  ‎Dec 23, 2009‎
Livalo has been tested again Pfizer's Lipitor and Merck's Zocor in patients with primary hyperlipidemia or mixed dyslipidemia. ... The IN VIVO Blog (blog)

Extending Intensive LDL-Lowering Boosts Benefits  -  ‎Dec 11, 2009‎
...(Zocor) -- actually "reduces events by about 50% over time," Christopher Cannon, MD, of Brigham and Women's Hospital in Boston, told MedPage Today. ... MedPage Today

ARBITER leaves some lasting marks on Merck  -  ‎Dec 21, 2009‎
Since then Zetia prescriptions in the US are down by about 30% and Vytorin—a combination of Zetia and Merck's Zocor—prescriptions are down by about 45%, ... Medical Marketing and Media

Avoid a bad drug trip  -  ‎Dec 11, 2009‎
Examples include: c Patients taking Zocor (simvastatin) in doses higher than 20 milligrams along with Cordarone (amiodarone) (prescribed to correct abnormal ... Washington Times

Senate to review rules for prescription drug plan managers  -  ‎Dec 11, 2009‎
Examples included a customer paying a $37.50 co-pay for Zocor, a cholesterol-lowering drug, which the PBM then billed the customer's insurance plan another ... Alaskajournal.com

Lilly, Kowa and Kowa Pharmaceuticals America Announce Co-Promotion and ...  -  ‎Dec 26, 2009‎
LIVALO offers a new statin option, with LDL lowering consistent with the commonly administered doses of Lipitor® and Zocor®, and significantly greater LDL ... AUTO-MOBI.info

ABT Seeks Simcor Label Expansion - Analyst Blog  -  ‎Dec 18, 2009‎
Simcor is a fixed-dose combination of Niaspan (niacin extended-release) and Merck's (MRK) Zocor (simvastatin), recommended for use in people who cannot ... Benzinga

릴리, 고와ì?˜ '리발로' ê³µë?™ íŒ?매 계약 ì²´ê²°  -  ‎Jan 3, 2010‎
...리발로는 ì?¼ë³¸ì—?서 합성ë?œ 스타틴으로 현재 í™”ì?´ìž?ì?˜ '리피토(Lipitor)'와 머í?¬ì?˜ 'ì¡°ì½”(Zocor)'등 ì?¼ë°˜ì ?으로 ë§Žì?´ 사용ë?˜ê³  있는 스타틴 약물과ì?˜ 비êµ? 시험등ì?´ ... 데일리팜

FDA:Vytorinä¸?太å?¯èƒ½æœƒå¢žåŠ ç™Œç—‡é¢¨éšª  -  ‎Dec 30, 2009‎
Vytorinçµ?å?ˆå…©ç¨®é™?膽固醇藥物,一種是默克藥廠的Zocorï¼›å?¦ä¸€ç¨®æ˜¯é»˜å…‹å’ŒSchering-Plough生產的Zetia。 FDA在2008å¹´8月表示,有份臨床試驗調查報告èª?為,Vytorin和癌症 ... 臺灣新浪網

FDA, "머í?¬ 'ë°”ì?´í† ë¦°' ì•” 유발하지 않아"  -  ‎Dec 22, 2009‎
...ë°”ì?´í† ë¦°ì?€ 머í?¬ì?˜ '제티아(Zetia)'와 'ì¡°ì½”(Zocor)'를 복합한 콜레스테롤 약물. 제티아와 ë°”ì?´í† ë¦°ì?€ 최고 매출ì?´ 50ì–µ 달러ì—? 달하기ë?„ 했었다. ... 데일리팜

Restructuration financière de la filiale marocaine de l'industriel ...  -  ‎Jan 4, 2010‎
Son portefeuille de médicaments commercialisés au Maroc couvre des domaines thérapeutiques différents comme la cardiologie (Zocor, Renitec. ... La Vie Éco

Ä?àn ông nên có chỉ số cholesterol thấp, vì nó ảnh hưởng mạnh đến ung thư tuyến ...  -  ‎Dec 14, 2009‎
Nhưng cái khó của cuộc thí nghiệm là các nhà khoa h�c không biết có bao nhiêu ngư�i đã dùng thuốc hạ cholesterol như Lipitor, Zocor hay Crestor và chính ... Cali Today

ASK DR. H: Breast lump linked to Zocor?  -  ‎Nov 11, 2009‎
The surgeon thought that the Zocor I was taking for my cholesterol might have caused it. After being off the Zocor, the area does seem to be much less ... Atlanta Journal Constitution

Study: Cholesterol drugs may improve flu survival  -  ‎Oct 29, 2009‎
A new treatment for swine flu may already be on pharmacy shelves — cholesterol-lowering statin drugs like Lipitor and Zocor. A large study found that people ... The Associated Press

Statins such as Lipitor and Zocor can damage your liver and kidneys  -  ‎Nov 8, 2009‎
Although statins such as Lipitor and Zocor are widely used to prevent heart attacks, strokes, and other cardiovascular disorders, new research shows that ... Examiner.com

Amateur Hour at Merck: FDA Refuses to Look at Zetia-Lipitor Combo Pill  -  ‎Nov 4, 2009‎
Merck needs some good news on Zetia and Vytorin, its Zetia-Zocor combo. In addition to the still-unfolding Arbiter-6 horror — in which signs point to ... BNET

Merck Cholesterol Pill Sales May Drop 20% After Study  -  ‎Nov 10, 2009‎
Vytorin combines Merck's bad-cholesterol blocker Zocor, now available as a generic drug, with Zetia. It's designed to hamper LDL cholesterol production in ... Bloomberg

Lower Cholesterol Lessens Risk Of Some Cancers  -  ‎Nov 10, 2009‎
However, researchers were not sure how many men participating in the study were taking statin drugs like Lipitor, Zocor or Crestor. ... Visit Bulgaria

lower cholesterol may cut risk of high-grade prostate cancer  -  ‎Nov 4, 2009‎
The research teams involved in both studies warn that they do not know how many men in the studies were taking statin drugs such as Lipitor, Zocor or ... eFitnessNow

People's Pharmacy: a cholesterol dilemma  -  ‎Oct 25, 2009‎
A: In searching the medical literature, we found an article in Drug Safety (July 2009) confirming that some statin-type drugs (Crestor, Lipitor, Zocor) are ... Houston Chronicle

Lowering cholesterol with statins and lessening heart disease  -  ‎Nov 2, 2009‎
You can hardly watch television these days without seeing commercials for statin drugs such as Lipitor and Zocor. ... MiamiHerald.com

Ask Dr. H: Pain in feet could be neuropathic  -  ‎Oct 19, 2009‎
I'm 85 years old, and take Synthroid, Diovan, Zocor, Coreg CR, Actonel, and a baby aspirin. Answer: It's difficult to say for certain why you've got ... Philadelphia Inquirer

Heart valve changes don't always warrant treatment  -  ‎Nov 3, 2009‎
Ezetimibe is combined with simvastatin (Zocor), which is a statin drug, the class of drugs that lower cholesterol by interfering with the liver's production ... Herald & Review

Pfizer earnings up 26% despite lower sales of many drugs  -  ‎Oct 21, 2009‎
...notably the generic version of Merck & Co's Zocor (simvastatin). Generic competition also hurt the colorectal cancer drug Camptosar (irinotecan), ... Pharma Times

Statins Protect Against Parkinson's Progression in Mice  -  ‎Nov 2, 2009‎
Mice given the equivalent of standard simvastatin (Zocor) or pravastatin (Pravachol) doses lost fewer dopaminergic neurons and neurotransmitters, ... MedPage Today

Alternative medicine is becoming mainstream  -  ‎Nov 10, 2009‎
A group taking the cholesterol medication Zocor saw a 39% LDL reduction. But many more of the therapies are unproven or untested. ... Los Angeles Times

Alternative medicine is becoming mainstream  -  ‎Nov 6, 2009‎
A group taking the cholesterol medication Zocor saw a 39% LDL reduction. But many more of the therapies are unproven or untested. ... Los Angeles Times

Swine Flu Hit Millions in Spring, Agency Says  -  ‎Oct 29, 2009‎
...researchers presented tantalizing preliminary evidence that statins — cholesterol-fighting drugs like Lipitor and Zocor — might help save people at risk ... New York Times

Stanols Squelch Cholesterol  -  ‎Oct 23, 2009‎
Simvastatin, sold under the brand name Zocor, is from the HMG-CoA reductase inhibitor drug family, sometimes referred to as “statins. ... Medfinds

Cholesterol Lowering Drugs Might Help Chances of H1N1 Flu Survival  -  ‎Oct 30, 2009‎
Lipitor and Zocor, popular drugs used for the purpose of lowering cholesterol levels, might greatly improve the chances of survival in the case of H1N1 flu, ... TopNews

Smart Rx: Drugs that work and won't break the bank  -  ‎Nov 4, 2009‎
Many patients are familiar with Merck's cholesterol-lowering pill Zocor, but they might not realize the drug is now available for a portion of its original ... The Associated Press

Maintaining Healthy Cholesterol Levels May Lower Risk of Prostate Cancer  -  ‎Nov 5, 2009‎
...men in the study who were taking cholesterol-lowering medications such as statin drugs, which include such name brands as Lipitor, Zocor, and Crestor. ... HealthNews

H1N1 pandemic developments at a glance  -  ‎Oct 29, 2009‎
The study looked at people who had been hospitalized for seasonal flu symptoms and found that those on statin drugs such as Lipitor or Zocor were twice as ... The Canadian Press

Prescription drugs that work and won't break the bank  -  ‎Nov 7, 2009‎
Many patients are familiar with Merck's cholesterol-lowering pill Zocor, but they might not realize the drug is now available for a portion of its original ... Abilene Reporter-News

Merck in a post-blockbuster world  -  ‎Oct 20, 2009‎
...such as multiple lawsuits over Vioxx and other medications, and the expiration of its blockbuster statin Zocor (for lowering cholesterol) in 2006. ... CNNMoney.com

EU Committee To Size Up Abbott, Solvay Cholesterol Drugs  -  ‎Oct 26, 2009‎
...(MRK) under the brand Zocor before it lost patent protection in 2006, has been proven to reduce cardiovascular risk in clinical trials. ... Wall Street Journal

BioCryst Pharmaceuticals receives $22.5 million from US government for ...  -  ‎Nov 5, 2009‎
...may improve flu survival A new treatment for swine flu may already be on pharmacy shelves — cholesterol-lowering statin drugs like Lipitor and Zocor. ... Gaea Times

What You Don't Know May Cost You When It Comes To Prescriptions  -  ‎Nov 4, 2009‎
Lipitor, Zocor, Pravacol and Crestor are all statins used to control cholesterol. But Lipitor and Crestor don't have generics. You need to ask for the ones ... WPXI.com

One-time gains boost AstraZeneca's 3Q  -  ‎Oct 29, 2009‎
Even in the face of generic Zocor, Crestor continues to post positive gains in the highly competitive statin market. 3. Concerns over the safety of COX-2 ... Hemscott

Cholesterol drug sales set to double  -  ‎Nov 6, 2009‎
Other than Lipitor, statins also include other top grossers like AstraZeneca's Crestor, Merck's Zocor and Mevacor, amongst others. Daily News & Analysis

UPI NewsTrack Health and Science News  -  ‎Nov 2, 2009‎
...(Zocor) and pravastatin (Pravachol) on two different types of brain cells -- neurons and astrocytes, which are support cells that help repair damage. ... United Press International

Judge refuses secondhand smoke testimony in South Dakota smoking ban lawsuit  -  ‎Nov 3, 2009‎
Dallas Morning News http://ff.im/aWv2e VerveHealth Verve Health Statins may prevent flu deaths: Cholesterol-lowering drugs such as Zocor, Crestor, ... Gaea Times

Merck Announces Third-Quarter 2009 Financial Results  -  ‎Oct 22, 2009‎
INVANZ, ISENTRESS, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN, TIMOPTIC/TIMOPTIC XE, TREDAPTIVE, TRUSOPT, VASOTEC/VASERETIC, ZOCOR and ZOLINZA. ... Reuters

United States: Keyword Advertising After Rescuecom: Predictability Remains Elusive  -  ‎Oct 28, 2009‎
Mediplan Health Consulting, Inc., 425 F.Supp.2d 402 (SDNY 2006) (use of plaintiff's mark ZOCOR allowable because defendants sold plaintiff's ZOCOR products ... Mondaq News Alerts (registration)

æœ?é™?膽固醇藥 æµ?感存活率增  -  ‎Oct 30, 2009‎
...一種å°?(H1N1)Aåž‹æµ?感的新療法,å?¯èƒ½æ—©å·²åœ¨è—¥å±€çš„貨架上了,那就是é™?低膽固醇的statin藥物,如Lipitor或Zocor。 一項大型研究發ç?¾ï¼Œæ„ŸæŸ“季節性æµ?感,並必須ä½?院治療的 ... 世界日報

Fármacos para reducir colesterol ayudarían a combatir la gripe A  -  ‎Oct 29, 2009‎
Los médicos quizá dispongan de un nuevo tratamiento contra la gripe del virus A H1N1: los fármacos para reducir el colesterol como Lipitor y Zocor. ... La Jornada de Morelos

Remédio para colesterol pode combater gripe, diz estudo  -  ‎Oct 29, 2009‎
...prateleiras das farmácias: as estatinas, remédios vendidos comercialmente com nomes como Lipitor e Zocor, usadas para diminuir os níveis de colesterol. ... Estadão

Des anti-cholestérols réduiraient le taux de mortalité des malades de la grippe  -  ‎Oct 30, 2009‎
MILWAUKEE, Wisconsin — Des médicaments anti-cholestérol comme le Lipitor et le Zocor réduiraient le taux de mortalité chez les malades de la grippe ... La Presse Canadienne

Таблетки, понижающие уровень холеÑ?терина, помогают от гриппа?  -  ‎Oct 29, 2009‎
Возможно, новое лекарÑ?тво от гриппа уже на полках магазинов - препараты, Ñ?нижающие уровень холеÑ?терина, такие как Lipitor или Zocor. ... Новости Америки

Breves del país  -  ‎Oct 30, 2009‎
Son las estatinas para disminuir el nivel de colesterol en la sangre, como Lipitor y Zocor. Un estudio de grandes proporciones halló que aquellos que toman ... La Raza

El consumidor gana con medicina genérica  -  ‎Nov 9, 2009‎
Cuando la patente para la droga llamada Zocor, utilizada para el tratamiento del colesterol, que es producida por el laboratorio Merck, expiró en 2006, ... El Informador

Statin berpotensi sebabkan sakit otot  -  ‎Oct 25, 2009‎
Center melibatkan 509 pasien yang menggunakan salah satu dari 3 jenis statin: atorvastatin (Lipitor), simvastatin (Zocor) atau pravastatin (Pravachol). ... Waspada Online

El colesterol bajo podría prevenir cáncer de próstata  -  ‎Nov 3, 2009‎
Sin embargo hay algunas salvedades: los investigadores no saben cuántos hombres en el estudio tomaban fármacos con estatinas como Lipitor, Zocor o Crestor. ... El Universo

Kolesterol Rendah Cegah Kanker Prostat  -  ‎Nov 4, 2009‎
Sejauh ini para peneliti tidak tahu berapa banyak laki-laki dalam penelitian ini memakai obat-obatan statin seperti Lipitor, Zocor atau Crestor. ... Inilah.com

Giảm cholesterol giúp ngăn ngừa ung thư tuyến tiá»?n liệt  -  ‎Nov 5, 2009‎
Nhưng kết quả này cÅ©ng không hoàn toàn rõ ràng vì các nhà nghiên cứu không biết bao nhiêu ngưá»?i trong nhóm này uống thuốc có chất statisn như Lipitor, Zocor ... Người Việt

Pfizer отчете 2 88 млрд. USD печалба за третото тримеÑ?ечие  -  ‎Oct 20, 2009‎
USD. ТърÑ?енето на леркарÑ?твото Ñ?рещу холеÑ?терол отчита Ñ?пад от 2006 г. наÑ?ам, когато на пазара излезе Zocor - подобно лекар. Пари

Effetti benefici della terapia con Inegy su un marker di aterosclerosi  -  ‎Nov 3, 2009‎
...in Italia: Sanaprav ) 40 mg, Simvastatina ( Zocor ) 40 mg, e all'associazione Ezetimibe 10 mg e Simvastatina 20 mg ( Inegy / Vytorin ). ... XagenaSalute

Merck Loses Protection for Patent on Zocor  -  Jun 23, 2006
By ALEX BERENSON. Today, Merck's cholesterol-lowering drug Zocor loses its United States patent protection, becoming the largest-selling drug yet to be ... New York Times

Merck Profit Falls as Generic Copies Hurt Zocor Sales  -  Jan 30, 2007
By Shannon Pettypiece. Jan. 30 (Bloomberg) -- Merck & Co.'s fourth-quarter profit plunged 58 percent as competition from generic copies of its medicines ... Bloomberg

Mixed Results for Lipitor Vs. Zocor  -  Nov 15, 2005
Robert Seidman, chief pharmacy officer at health insurer Wellpoint Inc., says there will always be a place for Lipitor, but that "there will be an expanded ... Washington Post

Teva Takes Round in Zocor Fight  -  May 1, 2006
By Robert Steyer. Teva Pharmaceutical Industries (TEVA:Nasdaq ADR) saw its shares climb Monday after the world's biggest generic-drug company won a round in ... TheStreet.com - TheStreet.com (subscription)

Generic Zocor Expected to Challenge Lipitor  -  Jun 16, 2006
By THERESA AGOVINO, AP Business Writer. NEW YORK — June 23 will be awful for Merck&Co., but the question looming is just how bad it will be for Pfizer Inc. ... FOXNews

Cholesterol Drug Zetia Doesn't Cut Heart Attack Risk: Study  -  Jan 14, 2008
But the new two-year trial of 720 patients sheds doubt on whether it makes any sense for people battling cholesterol to take Vytorin versus Zocor alone, ... Washington Post

Bad Cholesterol Up For Merck and Schering  -  Mar 31, 2008
Patients taking Zocor with ABT-335 saw their triglycerides fall 37.4%, versus a 14.2% decline when Zocor was taken alone. HDL levels rose 17.8% when both ... Forbes

Generic Zocor won't be a market healer: As lapse of patent protection...  -  Dec 29, 2005
Dec. 29--Consumers next year could be paying a lot less for their cholesterol pills the biggest selling class of prescription drugs--as a generic version ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Teva Wins OK to Sell Zocor Copy  -  Jun 24, 2006
Judge Royce C. Lamberth of the U.S. District Court for the District of Columbia denied a motion for a temporary restraining order filed by another generic ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Merck predicts Vytorin gains from Zocor defectors  -  Jan 3, 2008
NEW YORK, Jan 3 (Reuters) - The chief executive of Merck & Co (MRK.N) on Thursday said the company's Vytorin cholesterol fighter will likely get a future ... Reuters

Lipitor safer than Zocor - Pfizer study  -  Sep 5, 2007
Lipitor patients who switched to Zocor increased their chance of heart attacks, strokes, says Pfizer. By Aaron Smith, CNNMoney.com staff writer ... CNNMoney.com

Merck's 1st-Qtr Profit Falls 15% as Zocor Declines  -  Apr 21, 2005
By Juliann Walsh. April 21 (Bloomberg) -- Merck & Co., the third-largest US drugmaker, said quarterly profit fell 15 percent as sales of the company's ... Bloomberg

Vytorin study confuses patients - Heart health- msnbc.com  -  Jan 18, 2008
Instead, it showed $100-a-month Vytorin, which combines Zocor and Zetia, ... Such risk reduction has been proven in Lipitor and to some extent Zocor and ... msnbc.com

Senator Raps Drug Giant Over Zocor Price  -  Jun 20, 2006
By DEVLIN BARRETT, AP Writer. WASHINGTON — A New York senator accused the drug giant Merck&Co. on Tuesday of conspiring to undercut a cheaper generic ... FOXNews

Researchers deal Crestor another blow  -  May 23, 2005
But all of those side effects taken together were relatively rare, with Crestor causing 28 for every million prescriptions, Zocor 13 per million, ... USA Today

Regulators Clear 6 More Companies to Sell Generic Zocor  -  Dec 28, 2006
By BLOOMBERG NEWS. United States regulators have cleared six more companies to begin selling generic versions of Merck's cholesterol drug Zocor, ... New York Times

Generic Zocor reduces profits; Walgreens feels pain as drug price...  -  Oct 7, 2007
What's good for consumers with high cholesterol proved not to be so good for the nation's largest drugstore chain last week. ... Pay-Per-View - Chicago Tribune - ProQuest Archiver

A Backlash Against Vytorin?  -  Mar 30, 2008
Instead, the arteries of patients on Zocor became 0.006 millimeters thicker, ... Another, called SHARP, compares Vytorin, Zocor and placebo in patients with ... Forbes

… Labs gets FDA approval to sell generic form of Zocor in US - report  -  Dec 22, 2006
LONDON (AFX) - Ranbaxy Laboratories Ltd has received US FDA approval to manufacture and market its drug Simvastatin, a generic form of Merck's Zocor, ... Forbes

Article: Generic Zocor won't be a market healer: As lapse of patent …  -  Dec 29, 2005
Generic Zocor won't be a market healer: As lapse of patent protection looms, Merck and its rivals scramble to protect sales. ... find Chicago Tribune ... Pay-Per-View - Chicago Tribune - HighBeam Research

FDA defends cholesterol cutting as study goal  -  Jan 26, 2008
Vytorin combines Zocor with the companies' shared drug Zetia, which fights cholesterol in a different way. Many studies of statins have shown that people ... Reuters India

Kmart adds generic Zocor, other drugs to $15 plan  -  Jul 11, 2007
By Jessica Wohl. CHICAGO (Reuters) - Kmart said on Wednesday that it is adding more than 70 new generic medications to its discount drug program, ... Reuters

Merck to cut thousands of jobs; Cholesterol drug Zocor set to lose...  -  Nov 28, 2005
By Finfacts Team. US pharmaceutical firm Merck & Co. Inc. is expected to announce a major restructuring on Monday involving as many as several thousand job ... finfacts.com

… / PHARMACEUTICALS; Teva Gets Tentative OK to Sell Copies of Zocor  -  May 26, 2006
...s Zocor cholesterol drug, and said sales might start in June. Still at issue is the ability of Teva, the world's biggest generic drug maker, ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Schering-Plough earnings lower on Organon costs  -  Jul 21, 2008
Combined sales of Schering-Plough's newest cholesterol drugs, Zocor and Zetia, ... A combination of Merck's popular cholesterol agent Zocor and a newer drug ... MarketWatch

Merck And Schering's Problem Study  -  Dec 21, 2007
The study, called ENHANCE and started in June 2002, intended to prove that adding Zetia to Zocor caused less heart-attack-causing plaque to build up in ... Forbes

Markets; IN BRIEF/PHARMACEUTICALS; Shift From Lipitor to Zocor …  -  Oct 5, 2005
Analysts had been anticipating attempts to foster use of generic Zocor as companies, unions and others who provide health benefits seek ways to shrink ... Pay-Per-View - Los Angeles Times - ProQuest Archiver

Zetia - Cholesterol - Drug Trials - Heart - Medicine and Health - New...  -  Jan 22, 2008
The medicine combines Zocor, a cholesterol-lowering statin, with Zetia, ... The most popular — the statins, including Lipitor and Zocor — reduce the amount ... New York Times

Merck profit falls, hurt by charges, generic Zocor  -  Jan 30, 2007
NEW YORK (Reuters) - Merck & Co. (MRK.N) said on Tuesday fourth-quarter earnings fell sharply due to special charges and generic competition for its Zocor ... Washington Post

Article: Merck Prices Zocor Below Generic - The Washington Post | …  -  Jun 23, 2006
Merck Prices Zocor Below Generic ... find The Washington Post articles. Merck & Co. will price its Zocor cholesterol pill below Teva Pharmaceutical ... Pay-Per-View - Washington Post - HighBeam Research

New Merck chief plans for long-term recovery  -  Oct 25, 2005
Zocor lost almost a quarter of its overseas sales, where it faces strong competition from cheaper copycat drugs. The company also reported disappointing ... Times Online

Schering-Plough jumps on job-cut plan - MarketWatch  -  Apr 3, 2008
...s Zocor, which is now available generically at considerable discount to the price ... Vytorin is a combination of Zocor and a newer drug called Zetia. ... MarketWatch

Merck 3rd-Quarter Profit Falls on Zocor Competition  -  Oct 20, 2006
By Angela Zimm. Oct. 20 (Bloomberg) -- Merck & Co.'s third-quarter profit declined 34 percent as cheaper copies of its Zocor cholesterol pill, the company's ... Bloomberg

The Vytorin Question  -  Nov 19, 2007
Vytorin is a combo pill of Zetia and Zocor. Zocor or Vytorin was given to 720 patients with a genetic disorder that causes high cholesterol. ... Forbes

Vytorin, Zocor Label Change Seen 'Immaterial'  -  Aug 25, 2005
Merrill Lynch said a recent news report highlighting a label change for Vytorin and Zocor was "immaterial' and underscored heightened media scrutiny of drug ... Forbes

Merck, Schering to develop combo pill with Lipitor  -  Mar 26, 2007
Lipitor, Zocor and other statin medicines work in the liver to cut bad cholesterol, or LDL. Zetia, known generically as ezetimibe, blocks absorption in the ... Reuters

Vytorin On Trial  -  Mar 21, 2008
In 1994 and 1995, studies of Merck's Zocor, a Mevacor replacement, and Bristol-Myers ... But while artery thickness increased by 0.036 millimeters on Zocor, ... Forbes

Earnings: Kraft; Merck, Schering-Plough, American Express  -  Jul 24, 2006
Generic Zocor became available after Zocor's US patent lapsed late last month. Many insurers have aggressively tried to switch patients to generic Zocor ... FOXNews

Merck faces tough road after Vioxx, Fosamax setbacks - Jan. 28, 2005  -  Jan 28, 2005
Fosamax, with sales of $3.2 billion last year, is the company's second-biggest seller after cholesterol drug Zocor. Separately, securities regulators ... CNN International

Schering-Plough sees growth of cholesterol drugs  -  Jan 29, 2007
A cheaper generic form of Zocor reached US drugstores last summer after Zocor's patent ... Additional Zocor generics flooded into the market late last year, ... Reuters

Vytorin study results fuel cholesterol debate  -  Apr 7, 2008
Vytorin is a combination of two other cholesterol drugs: Zocor, a statin, ... The study -- called the Enhance trial -- compared Vytorin to Zocor alone. ... Los Angeles Times

Merck's Zocor price cut a mixed bag for drug cos  -  Jun 29, 2006
NEW DELHI: Merck's move to reduce prices of cholesterol-lowering drug Zocor in US may not be bad news for Indian generic players, mainly pharma major ... Times of India

Walgreen 4th-quarter net falls, shares drop  -  Oct 1, 2007
..."What's going on with Zocor is out of Walgreen's control," said Mitchell Corwin, analyst at Morningstar. "The higher store expenses, that's within their ... Reuters UK

Merck's Plan for a Comeback  -  Dec 16, 2005
For one thing, Merck hopes to market the improved niacin product in combination with Zocor, which lowers LDL, or bad cholesterol. But the drugmaker also has ... BusinessWeek

US judge denies injunction on Merck's Zocor generics  -  Jul 14, 2006
Washington, July 13A US district judge declined on Wednesday to issue a preliminary injunction blocking two companies from exclusively selling their generic ... Financial Express

Merck's Medicaid Settlement Covers Zocor, Vioxx and Pepcid  -  Feb 8, 2008
A former Merck employee will receive more than $68 million under a settlement that resulted in part from his lawsuit alleging that Merck violated the ... FDA news - FDA news (subscription)

Zocor Vs. Alzheimer's And Parkinson's  -  Jul 19, 2007
By none. What do you REALLY know about about flu shots, arthritic pain, nightcaps, antiperspirants, and healing cuts? (WebMD) Zocor, but not sister ... CBS News

Article: A shake-up beyond Merck: Zocor's patent protection ends. - …  -  Jun 18, 2006
2 cholesterol drug Zocor will expire, clearing the way for generic versions and ... Generic copies of Zocor may reduce Merck's revenue this year by ... ... Pay-Per-View - Philadelphia Inquirer - HighBeam Research

Schering's Buy of Organon Had to Happen  -  Apr 9, 2008
Ultimately, the devastating results -- indicating that Vytorin reduces plaque no more than Zocor alone -- would remain unknown for almost two full years. ... TheStreet.com - TheStreet.com (subscription)

Merck Posts Higher Profit, Lower Sales  -  Oct 24, 2005
Global sales of Merck's biggest product, Zocor, slumped 14 percent to $1.05 ... Zocor lost almost a quarter of its sales overseas, where it is facing ... FOXNews

Maker of Lipitor Digs in to Fight Generic Rival  -  Nov 3, 2007
While Lipitor itself is not available as a generic, a very similar drug made by Merck, Zocor, lost its patent protection last year. ... New York Times

Euphoria over cholesterol drug Zocor misplaced, say analysts  -  May 5, 2006
It may be too early to celebrate the prospects held out by cholesterol-lowering drug Zocor for Indian generic drug companies like Ranbaxy and Dr Reddy's, ... Hindu Business Line

Schering, Merck exceed expectations.  -  Apr 22, 2005
...prescription market share of more than 11 percent, Schering-Plough officials said, in a category that includes big sellers such as Lipitor and Zocor. ... $9.94 - Knight Ridder/Tribune Business News - Alacra Store

FDA investigates cholesterol drug  -  Aug 23, 2008
Vytorin is a combination of simvastatin, marketed as Zocor, and ezetimibe, marketed as Zetia. It was approved as a combination drug in 2004 to reduce ... United Press International

Schering-Plough, Merck slide on Vytorin woes  -  Dec 12, 2007
The study compared Vytorin with Merck's Zocor, another widely prescribed cholesterol agent that ... Vytorin is a combination of Zocor and the drug Zetia. ... MarketWatch

Teva Takes Round in Zocor Fight  -  Apr 24, 2006
The court's decision in the Zocor case is "definitely a positive surprise," says Deborah Knobelman of Piper Jaffray. Knobelman, who says she isn't sure if ... TheStreet.com - TheStreet.com (subscription)

… : Cholesterol choices: As brand-name drug Zocor goes generic, price...  -  Jun 30, 2006
Jun. 30--Millions of Americans who take cholesterol-lowering drugs will likely face a choice in the coming months. One cholesterol drug, Zocor, ... Free with registration - Fresno Bee - AccessMyLibrary.com

… takes aim at rival's effectiveness Study compares Lipitor to Zocor...  -  Nov 11, 2005
Any further competitive inroads by Zocor would erode ... A switch to Zocor could cut those costs substantially once it be comes a generic version. ... The Day - Google News Archive

Pfizer sees Lipitor sales toward lower end of view  -  Sep 10, 2007
...s (MRK) Zocor statin, which cleared the way for cheaper generic copies of Zocor. Although Zocor isn't identical to Lipitor, administrators of drug-benefit ... MarketWatch

Interaction Between Cholesterol, Heart Meds May Cause Muscle Damage  -  Aug 8, 2008
People who take the anti-cholesterol drugs Zocor (generic: simvastatin) or Vytorin ... Zocor and Vytorin, which contains the active ingredient in Zocor, ... ABC News

Zocor feeling the heat from generics  -  Jul 16, 2006
Late last month Merck's blockbuster cholesterol-lowering drug Zocor came off patent, and generic copycats are already cutting into its market share. ... FierceBiotech

Aiming for fiscal fitness Companies push for generic Zocor use to...  -  Jun 29, 2006
Some of North Texas' largest employers are asking workers to lower their cholesterol the generic way. Since a generic version of the popular Zocor pill ... $2.95 - Dallas Morning News - NewsBank

Generic statins to shrink prices, brand power of cholesterol pills.  -  May 20, 2006
The second-most widely prescribed statin, Zocor, is expected to be available late ... The generic version of Zocor, expected to be available by late June, ... Free with registration - Chicago Tribune - AccessMyLibrary.com

Teva Could See Upside On Generic Zocor Bid  -  May 10, 2006
Standard & Poor's Equity Research downgraded shares of Teva Pharmaceutical Industries after the Israeli drugmaker posted lower-than-expected results for the ... Forbes

… won't block generic doses of Zocor - Business - International...  -  Jun 23, 2006
WASHINGTON: A judge on Friday refused to block the US Food and Drug Administration from granting approval for generic versions of Merck's $4.4 ... New York Times

Diet pills can affect Zocor  -  Sep 4, 2006
I bought an herbal diet pill containing konjac glucomannan and Citrus aurantium. I also take Zocor, a multivitamin, fish oil, flaxseed oil and nine golden ... Los Angeles Times

Are You Taking Zocor?  -  Jun 20, 2006
This Friday, Merck's patent on the cholesterol - lowering drug Zocor will expire. There will now be a generic version of the drug for sale called ... ABC News

Justin Ferayorni: Lipitor Is the Key  -  Feb 9, 2006
Zocor, Merck's cholesterol drug, is the second most prescribed drug in the statin class in the US When it loses its patent exclusivity midyear, the generics ... TheStreet.com - TheStreet.com (subscription)

STRONG ZOCOR SALES BOOST MERCK PROFIT FORECAST  -  Apr 5, 2006
Drugmaker Merck said Tuesday that it anticipates posting a higher profit in the first quarter than originally expected because of strong sales of its ... $2.95 - San Jose Mercury News - NewsBank

Merck, Schering-Plough stocks win, Lilly down after earnings - Apr....  -  Apr 20, 2006
Merck attributed its earnings gain primarily to its $5 billion cost-cutting effort, but also first-quarter sales for its top-selling drug Zocor, ... CNNMoney.com

Statins don't appear to lower cancer risk, Results of studies touting...  -  Jan 4, 2006
Statins are the most commonly prescribed medications in the United States and as a result possess unrivaled name recognition: Lipitor, Zocor, Mevacor, ... Pay-Per-View - Newsday - ProQuest Archiver

Lipitor sales on track to hit record despite arrival of generic  -  Jul 20, 2006
2 anti-cholesterol drug, Zocor, went generic in late June. ... It also says about 60% of people who take Lipitor, Zocor, Vytorin and Crestor take less than ... USA Today

Pfizer earnings top forecasts but sales slip - Apr. 19, 2006  -  Apr 19, 2006
Some analysts say Lipitor sales could get squeezed by competition from a generic form of Zocor, the cholesterol-cutting drug from No. ... CNN

Another Storm Brewing For Vytorin  -  Aug 27, 2008
Each $4 Vytorin pill combines Zocor, a generic drug proved to prevent heart attacks and strokes, and Zetia, a weaker cholesterol drug for which there is no ... Forbes

AstraZeneca hits back in cholesterol wars  -  Jun 20, 2006
With Merck's blockbuster cholesterol drug, Zocor, losing patent protection on Friday, ... When Merck's patent on Zocor, also known as simvastatin, ... Independent

Mixed Findings for Pfizer  -  Oct 20, 2005
Last month, the company said it would guide customers to generic Zocor and away from Lipitor next year by removing Lipitor from its preferred list of ... TheStreet.com - TheStreet.com (subscription)

Lawmakers demand study data on Vytorin cancer risk  -  Aug 21, 2008
Vytorin combines Merck's now-generic statin drug, Zocor, with a different type of cholesterol drug, Zetia, made by Schering-Plough. ... San Diego Union - Tribune - San Diego Union Tribune

Merck faces loss of patent protection for top-selling Zocor - Jan....  -  Jan 30, 2006
Besides the Vioxx trials, the drug giant faces impending loss of patent protection on its top selling cholesterol drug Zocor. ... CNNMoney.com

High-dose Zocor cholesterol drug has mixed results  -  Nov 10, 2008
By Ransdell Pierson and Bill Berkrot. NEW YORK (Reuters) - A large study suggests that lowered levels of "bad" LDL cholesterol reduce risk of heart attacks ... Reuters India

Merck reports jump in quarterly profit - Earnings - MSNBC.com  -  Apr 20, 2006
The maker of blockbusters Fosamax for osteoporosis and Zocor for high ... Sales of top drug Zocor fell 4 percent to $1.06 billion, mainly because it now has ... msnbc.com

… says new study shows that Vytorin is better than Zocor - Mar. 13,...  -  Mar 13, 2006
Company says a study shows the cholesterol drug, which joins Zocor and Zetia, is better than Zocor alone. By Aaron Smith, CNNMoney.com staff writer ... CNNMoney.com

Zocor, Simvastatin Found to Disrupt Sleep Due to Fat Soluble …  -  Nov 7, 2007
Nov. 7, 2007 – Although the experts continuously tell senior citizens that sleep problems are not a normal part of aging, many find it hard to believe when ... SeniorJournal.com

Waiting For ENHANCE  -  Feb 5, 2008
Vytorin combines Zocor with a newer drug called Zetia that adds additional cholesterol-lowering oomph. It generates more than $5 billion in sales a year for ... Forbes

Merck, Schering-Plough Get Boosted After Beating Forecasts  -  Oct 20, 2006
Vytorin competes against Crestor, Lipitor and Zocor. Merck also owns Zocor, which achieved worldwide sales of $371 million in the third quarter, ... BusinessWeek

Merck's pipeline included drugs to treat cholesterol and HIV - Dec....  -  Dec 12, 2006
Zocor is a blockbluster cholesterol drug that lost patent protection in 2006. "I think the cholesterol combo is a sleeper blockbuster," said Les Funtleyder, ... CNNMoney.com

Merck Shows Some Upside | Robert Steyer News | Print Financial & …  -  Oct 24, 2005
Vytorin combines Schering-Plough's Zetia with Zocor. ... Zocor recorded worldwide sales of $1 billion in the third quarter, or 14% below the same period ... TheStreet.com - TheStreet.com (subscription)

Merck: Out Of The Ivory Tower  -  Mar 6, 2006
While drugs such as Zocor and Lipitor do a great job of cutting LDL, or bad cholesterol, they only slightly boost HDL, or good cholesterol. ... BusinessWeek

FDA rejections jolt 3 drugmakers Analysts see sign of shift in...  -  Apr 30, 2008
The drug, which had 2007 sales of $5 billion, combines Merck's older, cholesterol-lowering drug Zocor with Schering's Zetia. ... San Francisco Chronicle

Heart drug raises concern  -  May 25, 2005
That was about 2.2 times more than the adverse events seen with sim-vastatin, made by Merck under the brand name Zocor and 6.8 times higher than ... The Standard

Earnings and sales go way up at Teva - The generic-drug-maker said …  -  Aug 9, 2006
Teva's biggest new launch was simvastatin, a generic Zocor. ... Zocor produced $4.4 billion in sales for Merck & Co. Inc. last year. ... $2.95 - Philadelphia Inquirer - NewsBank

Priced Out Of Heart Disease  -  Jul 6, 2005
Kos is planning to market a combination of Niaspan and Zocor sometime after Zocor loses patent protection next year. All of this suggests that the current ... Forbes

Weak US dollar should boost Big Pharma earnings  -  Jul 19, 2008
A combination of Merck's popular cholesterol agent Zocor and a newer drug ... As a result, investors will be interested to see whether sales of Zocor and ... MarketWatch

Schering, Merck defend cholesterol drugs in ads  -  Jan 20, 2008
Vytorin combines Zetia and Zocor, known generically as simvastatin, into one pill. Vytorin did cut levels of "bad" LDL cholesterol more than Zocor, ... Reuters UK

Pharmaceuticals | Shock to the system | Economist.com  -  Jan 31, 2008
Concerned that the patent for its own statin, Zocor, was due to expire in 2006, ... It combined Zocor with Zetia, a cholesterol drug developed by ... economist.com

Merck And Schering Backtrack  -  Dec 11, 2007
Half the patients received Zocor, an older cholesterol-lowering drug, and half received Vytorin, a single-dose pill that combines Zocor with Zetia. ... Forbes

Merck unveils restructuring campaign.  -  Dec 16, 2005
Asked specifically about Merck having a role in the marketing a cheaper version of Zocor next year, Clark said, "It's a priority focus. ... Free with registration - Philadelphia Inquirer - AccessMyLibrary.com

Merck Can't Get Traction | Pharmaceuticals News | Print Financial & …  -  Dec 6, 2006
The best example is Zocor, which was Merck's biggest drug for many years. Zocor lost US patent protection in mid-2006. By the end of 2007, ... TheStreet.com - TheStreet.com (subscription)

House to Hold Vytorin Hearings | Newsweek To Your Health | Newsweek. …  -  Jan 30, 2008
From what I understand, it's just under $4 per pill for Vytorin and about $2 for Zocor [or generic versions]. That could be an issue for patients who are on ... Newsweek

The Real Problem With Those Vytorin Ads  -  Apr 14, 2008
Vytorin, by the way, combines Zocor and Zetia. And so in a January 23 letter to the drugmakers, the FDA noted that “Vytorin has not shown any additional ... Pharmalot

Pfizer's $13 Billion Bind  -  Feb 13, 2006
While Lipitor, Zocor and Pravachol work by cutting levels of bad cholesterol, or LDL, in the blood, torcetrapib aims to raise HDL, the so-called "good ... Forbes

Brand Names/Synonyms:
Zocor is also known by the following brand names and/or synonymsCCRIS 7558; Cholestat; Coledis; Colemin; Corolin; DRG-0320; Denan; Labistatin; Lipex; Liponorm; Lodales; MK-0733; MK-733; Medipo; Nivelipol; Pantok; Rendapid; Simovil; Simvastatin; Simvastatin [Usan:Ban:Inn]; Simvastatina [Spanish]; Simvastatine [French]; Simvastatinum [Latin]; Sinvacor; Sivastin; Synvinolin; Vasotenal; Vytorin; Zocor; Zocord

Drug Category:
Zocor is categorized under the following by the FDA: Antilipemic Agents; Anticholesteremic Agents; HMG-CoA Reductase Inhibitors; ATC:C10AA01

Dosage Forms:
Oral tablets

Absorption:
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues

Interactions:
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Chemical IUPAC Name:
[8-[2-(4-hydroxy-6-oxo-tetrahydropyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]2,2-dimethylbutanoate





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