Zopiclone

This page contains recent news articles, when available, and an overview of Zopiclone but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Zopiclone (when available)

Pharmacology and use:
Zopiclone is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class and is indicated for the short-term treatment of insomnia. While Zopiclone is a hypnotic agent with a chemical structure unrelated to benzodiazepines, barbiturates, or other drugs with known hypnotic properties, it interacts with the gamma-aminobutyric acid-benzodiazepine (GABA_BZ) receptor complex. Subunit modulation of the GABA_BZ receptor chloride channel macromolecular complex is hypothesized to be responsible for some of the pharmacological properties of benzodiazepines, which include sedative, anxiolytic, muscle relaxant, and anticonvulsive effects in animal models. Zopiclone binds selectively to the brain alpha subunit of the GABA A omega-1 receptor. For the short-term treatment of insomnia.

Mechanism Of Action:
Zopiclone exerts its action by binding on the benzodiazepine receptor complex and modulation of the GABA_BZ receptor chloride channel macromolecular complex.

News Articles on Zopiclone

Scots get £1m of drugs to treat sleep disorders  -  ‎Dec 30, 2009‎
The Scottish Government yesterday said most prescriptions were for benzodiazepines and another group of drugs – Zaleplon, Zolpidem and Zopiclone. ... Aberdeen Press and Journal

Hong Kong: Festive season appeal against drug abuse (with photos)  -  ‎Dec 18, 2009‎
The number of abusers of cough medicine (10.8% higher) and triazolam/midazolam/zopiclone (2.8% higher) also increased. Smaller numbers of abusers of ecstasy ... pluGGd.in

�?於�?度憂鬱症併用抗憂鬱藥物治療比單用Fluoxetine更有效  -  ‎Jan 3, 2010‎
...病患的精神異常藥物在�?步篩�?�之後�?�用，但是�?許維�?clonazepam�?zopiclone和zolpiderm，以控制焦慮和其他症狀。 �?步�?果測�?為HAM-D分數之改變。 ... 臺灣新浪網

Inquest rules man's death was accidental  -  ‎Oct 29, 2009‎
A post-mortem examination showed Mr Fry had swallowed more than 10 times the usual amount of the sleeping tablet Zopiclone. Deputy Bridgend coroner Huw ... WalesOnline

Calgary police arrest eight in dial-a-dope bust  -  ‎Nov 4, 2009‎
...police retrieved 68.4 grams of crack cocaine valued at $6800, as well as ecstasy, morphine, marijuana, OxyContin, Oxycodone, Zopiclone, Temazepam, ... Calgary Herald

Study confirms Zolpidem effect in brain damage  -  ‎Nov 8, 2009‎
This effect could not be reproduced with placebo or another sedative with a similar pharmacological action called zopiclone. ReGen has filed a new patent ... PR-Inside.com (Pressemitteilung)

Bipolar II Postpartum Depression: Detection, Diagnosis, and Treatment  -  ‎Nov 2, 2009‎
During withdrawal from venlafaxine the patient's insomnia worsened, leading her treatment team to substitute 25 mg of quetiapine for the zopiclone she had ... Am J Psychiatry (subscription)

Drug mistake 'cut disabled teenager's life by three years'  -  Jul 22, 2008
He was given the drugs Zopiclone, a sedative, and Co-codamol, ... She said she was also handed a note by a doctor, which said: "Zopiclone (caused ... Telegraph.co.uk

MP worked for City investment company while on sick leave from …  -  Oct 22, 2008
...between January and July this year on his GP's advice, and says he suffered from depression, bulimia, and an addiction to the sleeping pill Zopiclone. ... Telegraph.co.uk

CBT may be more effective than zopiclone for insomnia in the elderly.(...  -  Sep 1, 2006
Results from a new randomized, double-blind, placebo-controlled trial suggest that interventions based on cognitive behavioral therapy (CBT) may be more ... Free with registration - Brown University Geriatric Psychopharmac... - AccessMyLibrary.com

Cognitive therapy superior to zopiclone for insomnia.(POEMs[R]:...  -  Oct 1, 2006
Cognitive behavioral therapy (CBT), consisting of one 50-minute session per week for 6 weeks, is significantly more effective than zopiclone (Imovane) in ... Free with registration - Journal of Family Practice - AccessMyLibrary.com

… of Controlled Substances: Placement of Zopiclone Into Schedule IV  -  Apr 4, 2005
SUMMARY: With the issuance of this final rule, the Deputy Administrator of the Drug Enforcement Administration (DEA) places the substance, zopiclone, ... Pay-Per-View - Federal Register - Factiva, from Dow Jones

Zopiclone (Systemic).  -  Feb 1, 2006
Zopiclone ZOP-i-klonebelongs to the group of medicines called central nervous system (CNS) depressants (medicines that make you drowsy or less alert). ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… of controlled substances: Placement of zopiclone into Schedule IV.  -  Feb 14, 2005
This proposed rule is issued by the Deputy Administrator of the US Drug Enforcement Administration (DEA) to place the substance zopiclone, including its ... Free with registration - Asia Africa Intelligence Wire - AccessMyLibrary.com

Cognitive Behavioral Therapy Appears More Effective Than Sleep …  -  Jun 29, 2006
The zopiclone group did not differ significantly from the placebo group. Total wake time at 6 weeks was reduced 52 percent in the CBT group compared with 4 ... Medical News Today - Medical News Today (press release)

CBT more effective than zopiclone for insomnia.(cognitive behavioral ...  -  Aug 1, 2006
Cognitive-behavioral therapy led to greater improvements in a variety of sleep measures than did zopiclone in adults with insomnia, Norwegian researchers ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Imovane - Zopiclone - Medical Drug  -  May 10, 2008
Imovane is used to relief insomnia. It is used for short term treatment and is not recommended for use for more than 4 weeks at a time. ... Virtual Medical Centre - The Virtual Medical Centre

Cognitive Behavioral Therapy vs Zopiclone for Treatment of Chronic …  -  Jun 28, 2006
Børge Sivertsen, PsyD; Siri Omvik, PsyD; Ståle Pallesen, PhD; Bjørn Bjorvatn, MD, PhD; Odd E. Havik, PhD; Gerd Kvale, PhD; Geir Høstmark Nielsen, PsyD; ... Journal of American Medical Association - Journal of American Medical Association...

… of controlled substances: placement of zopiclone into Schedule IV.  -  Apr 4, 2005
With the issuance of this final rule, the Deputy Administrator of the US Drug Enforcement Administration (DEA) places the substance, zopiclone, ... Pay-Per-View - Federal Register - Factiva, from Dow Jones

Pronunciation : zoe' pi clone  -  Jun 29, 2008
Why it is prescribed (Indications) : Zopiclone is used on a short-term basis to ... When it is to be taken : Zopiclone is taken at bedtime when needed. ... MedIndia

Article: CBT more effective than zopiclone for insomnia.(cognitive …  -  Aug 1, 2006
CBT more effective than zopiclone for insomnia.(cognitive behavioral therapy)(Editorial) ... find Clinical Psychiatry News articles. Pay-Per-View - Clinical Psychiatry News - HighBeam Research

… : COGNITIVE BEHAVIOUR THERAPY BETTER THAN ZOPICLONE  -  Oct 26, 2006
The investigators identified 46 adults with a mean age of 61 who met DSM-IV criteria for chronic insomnia. Eligible patients were randomised (concealed ... Pay-Per-View - Pulse - Factiva, from Dow Jones

安眠藥Zolpidem Zopiclone 疑致�?�食症  -  Sep 19, 2008
...�?明報專訊】失眠人士常�?用安眠藥幫助入眠，但有�?�想�?��?功入�?�的代價�?�能是患「�?� 食症�?——�?然夢�?�到廚房煮麵�?�？中大一項研究發�?�，部分在市�?�上常見的安眠藥會出�?� ... 香港新浪網

Drug abusers down 5.2%  -  Mar 23, 2006
There was a general rise in use of most other popular types of psychotropic substances, such as ecstasy, ice, triazolam, midazolam, zopiclone, and cough ... news.gov.hk

CBT Is More Effective Than Sleeping Pills  -  Aug 16, 2006
Zopiclone was unchanged from the 6-week value. Total wake time and sleep efficacy were ... Total wake time was less in the CBT than in the zopiclone group. ... HealthandAge.com

Drugged vs Drowsy Driving  -  Nov 3, 2005
These so-called Z drugs include zopiclone, zolpidem, and zaleplon. With regard to producing driving impairment, zopiclone was comparable to the ... Sleep Review

�?圖與�?�?�死心�?�治療�?�年  -  Aug 13, 2008
...今年1月9日，她在絕望下一心與�?�?�死，到藥房買了30粒安眠藥�?匹克隆（ Zopiclone），在寓所附近公園�?�兒�?說：「食藥後�?�以上太空�?，便將12粒安眠藥給他�?用，惟她�? ... 蘋果日報

Questions & Answers.(sleep medication)  -  Apr 1, 2005
Lunesta is a version of zopiclone, which has been on the market around the ... Zopiclone molecules, like many drugs, can be oriented two ways in space. ... $4.95 - Harvard Mental Health Letter - ECNext

The Safety of Long-Acting Beta Agonist Inhalers Pharmacology Watch  -  Aug 1, 2006
Cognitive behavioral therapy is more effective than zopiclone for the treatment of ... For most outcomes, zopiclone did not differ from placebo (JAMA. ... Free with registration - Infectious Disease Alert - AccessMyLibrary.com

Cognitive Behavioral Therapy Appears More Effective Than Sleep Meds …  -  Jun 22, 2006
The zopiclone group did not differ significantly from the placebo group. Total wake time at 6 weeks was reduced 52 percent in the CBT group compared with 4 ... newswise.com

Zopiclone Gnr - Précautions, Posologie, Grossesse, Conduite, Comment ...  -  Jul 18, 2005
En raison de la présence de lactose, ce médicament est contre-indiqué en cas de galactosémie congénitale, de syndrome de malabsorption du glucose et du ... Santé AZ

Study Demonstrated ROZEREM(TM) (ramelteon) Does Not Affect Middle- …  -  Jun 13, 2007
However, the positive control, zopiclone, did show a statistically significant difference ... For zopiclone the mean log of COP after dosage was 3.539 cm2, ... Free with registration - PR Newswire - AccessMyLibrary.com

Sleepless nights  -  Jun 9, 2008
A Your dependence on Zopiclone (Imovane) on a long-term basis is both unwise ... The use of alcohol along with Zopiclone is also unwise as it is likely to ... AsiaOne

ROZEREM (Ramelteon) Does Not Affect Body Sway, Demonstrated By …  -  Jun 20, 2007
However, the positive control, zopiclone, did show a statistically significant difference ... For zopiclone the mean log of COP after dosage was 3.539 cm2, ... Medical News Today - Medical News Today (press release)

Cognitive behavioral therapy appears more effective than sleep …  -  Aug 29, 2006
The zopiclone group did not differ significantly from the placebo group. Total wake time at 6 weeks was reduced 52 percent in the CBT group compared with 4 ... Natural News.com

Sleeping Difficulty Treatment - Sleeping Difficulty Health Information...  -  May 29, 2008
In a 2006 study of older adults, CBT worked better than zopiclone (Imovane) in ... [Zopiclone is a European sleep medication that is similar to the American ... New York Times

Press Release: Study Demonstrated ROZEREM(TM) (ramelteon) Does …  -  Jun 13, 2007
However, the positive control, zopiclone, did show a statistically significant ... For zopiclone the mean log of COP after dosage was 3.539 cm2, (P ... Pay-Per-View - PR Newswire - HighBeam Research

Sleeping pill risks found to outweigh benefits  -  Aug 12, 2008
A closely related drug, zopiclone, has also come under scrutiny and the warnings in the latest NPS position statement also apply to it. ... The Australian

Sleep Talking  -  Apr 9, 2007
It compared a Lunesta-style drug (zopiclone) with six sessions of CBT in 46 men and women who had struggled with insomnia for at least three months. ... Forbes

International Drug Scheduling; Convention on Psychotropic Substances;...  -  Dec 13, 2005
4.1 If zopiclone is placed under international control, do you think that its availability for ... Zopiclone is classified as a nonbenzodiazepine hypnotic. ... Pay-Per-View - Federal Register - Factiva, from Dow Jones

People turn blue in a search for sleep  -  Sep 2, 2008
People suffering from the effects of zopiclone can die from a shortage of oxygen if they do not receive an antidote immediately. ... The Standard

Neurocrine Announces Peer-Reviewed Publication of Indiplon …  -  Apr 5, 2006
Zopiclone and zaleplon showed little or no subtype selectivity, and zolpidem showed moderate selectivity for alpha 1 versus alpha 2 and 3 containing ... Free with registration - PR Newswire - AccessMyLibrary.com

Insomnia drove me to the edge and nearly destroyed my marriage  -  Jan 28, 2008
After a few days of taking it, the Zopiclone would knock me out for a few hours, ... I came off the Xanax and Zopiclone, tapering slowly so as not to get ... Daily Mail

Cant Sleep - Help!  -  Oct 5, 2007
Thanks for reply and hope you get a better night than I do I am on Zopiclone 7.5 and 3.5 pills a night and Diazepam 10Mgs and lot more pilsbeen on since 17 ... Daily Mail

Advogato: Blog for pfh  -  Jan 1, 2005
I am taking: propranolol, zopiclone, modafinil (though all in moderate amounts). Oh well. ... So, I am off propranolol, hopefully off zopiclone, ... Advogato

Coroner unable to pinpoint cause of fatal fire  -  May 28, 2007
Ms James had taken codeine and the sedative Zopiclone, which Mr Evans said could have ... Her levels of Zopiclone were two times higher than for normal use. ... New Zealand Herald

Terapia cognitivo comportamentale nell'insonnia  -  Sep 12, 2007
I soggetti trattati con zopiclone potevano continuare ad assumere il farmaco anche dopo la sesta settimana. Il sonno è stato misurato sia in maniera ... Pillole.org

Department of State Health Services  -  Nov 11, 2005
...(3) Abuse of zopiclone may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in Schedule III. ... Pay-Per-View - RegAlert - Factiva, from Dow Jones

A CLOSER LOOK RESEARCH FINDINGS | Article from The Milwaukee …  -  Jul 3, 2006
Caveats: People taking zopiclone reported the following side effects: bitter taste, dry mouth, daytime drowsiness, light nausea, headache and chest pain. ... Pay-Per-View - Milwaukee Journal Sentinel - HighBeam Research

Sleeping Pills Can Increase Risk Of Traffic Accidents  -  Feb 8, 2008
The risks after dispensing zopiclone, zolpidem and nitrazepam were comparable and ... These new results are alarming because zopiclone and zolpidem are ... Medical News Today - Medical News Today (press release)

A case of late-onset chorea  -  Jul 13, 2005
Medications included hormone replacement therapy (HRT), diclofenac sodium, vitamin D, folic acid, methotrexate and zopiclone. ... Nature.com

Record Sales of Sleeping Pills Are Causing Worries  -  Feb 7, 2006
Dr. Carlat cited a 1998 study in Britain, published in The Lancet, which found that taking zopiclone, the compound known as the "mother" of Lunesta and ... New York Times

Sleeping pills 'double' risk of having car crash the next day  -  Nov 24, 2008
There were 129 accidents after taking zopiclone, and 21 for zolpidem. They found that those who took the z-type for a few weeks at a time were at just as ... Daily Mail

Sometimes the humble GP sees a miracle that research couldn't find  -  Sep 17, 2006
No one has any idea why Zopiclone should have this remarkable effect. But "before and after" brain scans performed by Dr Ralph Clauss, of the Royal Surrey ... Telegraph.co.uk

Behavioral Therapy 1, Sleeping Pills 0  -  Jun 27, 2006
...pill zopiclone, a drug that is very similar to Sepracor's Lunesta and was originally sold by Sanofi-Aventis in Europe; a third patient-arm got placebo. ... Forbes

Second opinion: original vision  -  Sep 19, 2006
No one has any idea why Zopiclone should have this remarkable effect. But "before and after'' brain scans performed by Dr Ralph Clauss, of the Royal Surrey ... Telegraph.co.uk

Management of insomnia: treatments and mechanisms  -  Dec 6, 2007
Benzodiazepines and the Z-drugs (zolpidem and zopiclone, and to a lesser extent ... In a placebo-controlled trial of the active (S) enantiomer of zopiclone ... British Journal of Psychiatry (subscript...

Sepracor's Lunesta an immediate success in burgeoning market for …  -  Jul 24, 2005
Lunesta is a new version of an old insomnia medication called zopiclone, ... Lunesta has a slightly different molecular structure than zopiclone, ... $1.95 - Worcester Telegram Gazette - NewsBank

Heroin and sleeping pill taken before death of prisoner  -  Oct 15, 2008
...postmortem toxicology reports on blood and urine samples indicated he had used heroin and a sleeping tablet, Zopiclone, in the hours before his death. ... Irish Times

Behavioral therapy better than meds for treating insomnia.(treatment ...  -  Oct 1, 2006
After six weeks of treatment, total wake time decreased by 52 percent in the CBT group, compared with 4 percent with zopiclone and 16 percent with placebo. ... Pay-Per-View - Focus on Healthy Aging - HighBeam Research

記者稱失眠輕易購�?藥  -  Sep 19, 2008
...�?明報專訊】是次研究指出，兩種市�?�上有售的安眠藥Zolpidem�?�Zopiclone較容易 ... 其中俗稱「鸚鵡�?或「白瓜�?�?的Zopiclone因價錢便宜更�?�歡迎，香港中毒諮詢中心早 ... 香港新浪網

Treatment options for insomnia.(Disease/Disorder overview)(Clinical …  -  Aug 15, 2007
Eszopiclone, an isomer of zopiclone, is the only hypnotic with FDA approval ... Quick reference guide: zaleplon, zolpidem and zopiclone for the short-term ... $4.95 - American Family Physician - ECNext

Article: Tablets lost; Local News Extra KIDDERMINSTER.(News) - …  -  Aug 22, 2007
Seven Zopiclone tablets and 42 Diazepam tablets, which can cause drowsiness, dizziness, dry mouth, upset stomach and a change in appetite, went missing at ... Pay-Per-View - Birmingham Mail - HighBeam Research

STEPS - June 15, 2005 - American Family Physician  -  Jun 15, 2005
Rare cases of fatal overdose with zopiclone and concomitant central nervous system (CNS) depressants have been reported in European post-marketing studies.1 ... AAFP News Now

Washington Week . Student Voices | PBS  -  May 6, 2005
Ketamine, Scopolamine and Zopiclone, and alcohol are also commonly used to spike both alcoholic and non-alcoholic drinks. ... PBS

Schedule IV(US)  -  Oct 18, 2005
Other benzodiazepines and zolpidem and zopiclone are also found in high numbers of suspected drugged drivers. Many drivers have blood levels far exceeding ... chemie.de

La thérapie comportementale et cognitive contre l'insomnie  -  Jun 30, 2006
Ces bénéfices seraient supérieurs à ceux apportés par un traitement pharmacologique par zopiclone contre l'insomnie de l'adulte, selon une étude publiée ... Caducée.net

Parole per dormire  -  Jun 30, 2006
I partecipanti sono stati randomizzati fra terapia comportamentale, zopiclone (7,5 milligrammi a notte) e placebo. Ogni trattamento è durato 6 settimane, ... Dica 33

Advogato: Blog for pfh  -  Jan 13, 2005
I am taking: propranolol, zopiclone, modafinil (though all in moderate amounts). Oh well. I bought a digital metronome. It stutters and misses beats, ... Advogato

Pharmacy update: Head for bed.(treatment for sleep disorder)  -  Jan 28, 2006
Zopiclone has an elimination half-life of 3.5-6.5 hours. Like the others, it is indicated for short-term treatment of insomnia, with a single period of ... Free with registration - Chemist & Druggist - AccessMyLibrary.com

Neurocrine Biosciences Reports First Quarter 2006 Results.  -  Apr 24, 2006
...sleep agents zolpidem (Ambien(R)), zaleplon (Sonata(R)) and zopiclone (Imovane(R), which is the racemic form of s-zopiclone [Lunesta(R)]). ... Free with registration - PR Newswire - AccessMyLibrary.com

Medic stole pills forms.  -  Jan 13, 2006
The prescription and others had been made out by Farah for 56 Zopiclone tablets each in the name of different patients and signed by different doctors. ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

Drugs and booze mix up led to death  -  Nov 1, 2008
He gave the cause of death as heroin toxicity with alcohol, zopiclone and diazepam. The hearing was told how Mr Dowson had earlier been assaulted during a ... GazetteLive

Man's 'insomnia drug' left teen fighting for life.  -  Apr 28, 2006
The 16-year-old, who had been drinking, was given a Zopiclone tablet by 51-yearold John Young, ... "It can't be said the Zopiclone caused all the problems, ... Free with registration - Europe Intelligence Wire - AccessMyLibrary.com

Stilnox/Ambien/Imovane: The Sleep Drugs That Can Kill  -  Mar 13, 2008
Stilnox is a non-benzodiazepine hypnotic drug classed as a Z-class drug along with Zolpidem, zopiclone, zaleplon. The Z-class drugs are used instead of ... Natural News.com

Sleep drugs go missing  -  Nov 29, 2006
The drugs, 14 tablets of zopiclone, could lead to unconsciousness and also ... Zopiclone is prescribed to help people with sleeping problems and works by ... Crewe Chronicle

Sleep better with cognitive behavioral therapy  -  Jun 30, 2006
They looked at 46 adults who had chronic sleep problems to compared cognitive behavioral therapy (CBT) with the sleep drug zopiclone and placebo. ... HealthandAge.com

Trattamento dell'insonnia negli anziani: ipnotici non-benzodiazepinici  -  Sep 18, 2007
Sulla base dei dati clinici disponibili, Zopiclone, Zolpidem, Zaleplon, Eszopiclone e Ramelteon rappresentano trattamenti modestamente efficaci, ... XagenaSalute

Melatonin.(Monograph)  -  Dec 1, 2005
The sleep-inducing potential of test medications (in decreasing order of effect) was: zopiclone>zaleplon>melatonin >temazepam. (66) The researchers (using ... Free with registration - Alternative Medicine Review - AccessMyLibrary.com

Access to Legal Drugs Fueling Teen Drug Culture  -  Dec 21, 2006
Entries include such illegal substances as LSD. But nestled between ecstasy and the veterinary tranquilizer ketamine is zopiclone -- ABC News

HEATH LEDGER'S TRAGIC DEATH  -  Jan 23, 2008
Found on his nightstand, sources said, was a bottle of Donormyl, an antihistamine used as a sleep aid, and a packet of the drug Zopiclone, also used for ... New York Post

Federal Register 2005 - 70 FR 73775 International Drug Scheduling; …  -  Dec 13, 2005
Zopiclone (INN) As a follow-up for the thirty-third meeting of the Expert Committee on Drug Dependence, final decisions will be taken for buprenorphine ... Pay-Per-View - Federal Register 2005 - Loislaw

Factiva Search  -  Mar 21, 2005
...zopiclone Sanofi-Aventis, Meda licensing agreement.(Brief Article) ... MEDA announced on 7 February 2005 the acquisition of rights to zopiclone (IMOVANE ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Kentucky Regulations - 902 KAR 55:030. Schedule IV substances. [ …  -  Aug 10, 2005
...(35) Prazepam; (36) Quazepam; (37) Temazepam; (38) Tetrazepam; (39) Triazolam; (40) Zaleplon; (41) Zolpidem; and (42) Zopiclone. Section 3. Fenfluamine. ... Pay-Per-View - Kentucky Regulations - Loislaw

Internet GP gets nine-month suspension  -  Feb 21, 2007
A third patient obtained 51 repeat prescriptions for two highly addictive sleeping tablets, Zolpidem and Zopiclone, and only received a five-minute ... guardian.co.uk

Online doctor put patients at risk, hearing told  -  Feb 13, 2007
He admits prescribing Zolpidem and Zopiclone to Patient X, and that this was excessive, irresponsible and not in his best interests. ... guardian.co.uk

Mary-Kate Olsen called before Ledger's ambulance  -  Jan 25, 2008
...and Lorazepam (Ativan) were found in his apartment, along with Ambien and Zopiclone (Lunesta) sleeping pills and the sedative Temazepam (Restoril). ... NEWS.com.au

Hollywood to mourn Heath Ledger's loss  -  Jan 25, 2008
Two types of sleep aids, Donormyl and Zopiclone, were found next to Ledger, whose cause of death remains under review. "The pills generally have a large ... NEWS.com.au

PRESS DIGEST - Hong Kong - Sept 2  -  Sep 1, 2008
At least 10 people were poisioned, and their complexion turned blue, in the past two years after taking sleeping pills containing the chemical zopiclone. ... Reuters

Man's medicines stolen in robbery  -  Feb 8, 2007
They grabbed hold of his Nike rucksack and ran off with it and the money, clothing and Diazepam and Zopiclone it contained. ... BBC News

Mother, 67, confesses to killing her Down's son  -  Sep 24, 2005
Police said Patrick died of plastic bag suffocation while intoxicated on zopiclone, a sleeping pill. At a 15-year-minute hearing at Reading Crown Court, ... Times Online

Ελευθε�?οτυπία - Απογευματινή Αδέσμευτη Εφημε�?ίδα  -  Sep 19, 2006
Ο δ�? �?ελ αποφάσισε να του χο�?ηγήσει το καταπ�?αϋντικό φά�?μακο Zopiclone. ... Κανείς δεν έχει την πα�?αμικ�?ή ιδέα γιατί το φά�?μακο Zopiclone έχει αυτήν την ... Ελευθε�?οτυπία

Concern after medication is lost  -  Jun 24, 2007
The items including liquid methadone, methadone ampoules and Zopiclone tablets, were in a handbag lost in Bank Gardens, Stroud. ... BBC News

Insomnia Medications - Insomnia Health Information - NY Times Health  -  Feb 6, 2008
Eszopiclone is related to zopiclone (Imovane), which has been used for many years in Europe. Unlike other sleep medications, eszopiclone can be taken on a ... New York Times

Can't sleep? Try changing your behavior  -  Jun 27, 2006
...less time awake at night compared to patients on the sleeping pill zopiclone. In fact, the sleeping pill did no better than the placebo in many ways. ... msnbc.com

No rest for the busy  -  Jun 20, 2008
In the 18th Century insomniacs took opium, and later, in the 19th, potassium bromide, while they now guzzle zopiclone, valium and temazepam - doctors write ... BBC News

Does anything help with jet lag?  -  Aug 11, 2008
The sleeping tablets that have been studied for jet lag are zolpidem (brand name Stilnoct) and zopiclone (Zimovane). You can only get these on prescription ... guardian.co.uk

Newsweek - National News, World News, Health, Technology, …  -  Jan 23, 2008
...found six drugs with European prescriptions in Ledger's apartment: Zopiclone, Diazepam, Lormetazepam, Temazepam, Alprazolam and Donormyl-doxylamine. ... Newsweek

Warning over 'lethal' medication  -  Sep 15, 2006
Police are urging anyone who finds the bag, containing more than 200mg of Zopiclone, Carbamazepine and Mirtazepine, to hand them in. ... BBC News

Ledger's former fiancee back in New York  -  Jan 25, 2008
Diazepam (Valium) and Lorazepam (Ativan), the sleeping medication Zopiclone (Lunesta) and the sedative Temazepam (Restoril), reports TMZ. ... Pittsburgh Post-Gazette - Pittsburgh Post Gazette

Kiwi bank blocks customers using Marketscore  -  Mar 16, 2005
She claimed that it was the cyber equivalent of giving a stranger the keys to the front door of your home, the alarm code and feeding the dog with zopiclone ... Inquirer

DOC SAYS ACCIDENT UNLIKELY  -  Jan 24, 2008
Two types of sleep aids, Donor myl and Zopiclone, were found next to Ledger, whose cause of death remains under review by authorities. ... New York Post

New warning on sleeping pill  -  Feb 22, 2008
Z-class drugs - zolpidem, zopiclone and zaleplon - are non-benzodiazepine hypnotics that are used as alternatives to drugs such as Valium and Rohypnol. ... Brisbane Times

Article: Try CBT first for anxiety in children.(Child/Adolescent...  -  Mar 1, 2008
Article: CBT more effective than zopiclone for insomnia.(cognitive ... Clinical Psychiatry News; August 1, 2006 ; 700+ words ... ... among older patients ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

CBT's role in treatment of schizophrenia is growing.(Adult Psychiatry)...  -  Oct 1, 2007
Article: CBT more effective than zopiclone for insomnia.(cognitive ... Clinical Psychiatry News; August 1, 2006 ; 700+ words ... ... among older patients ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

Heath and a prescription for disaster  -  Jan 27, 2008
What mind-messing junk it was, too: everything from the powerful and controversial sleeping pills Ambien and Zopiclone, to the antidepressant Zoloft, ... Mirror.co.uk

Did a sleeping pill end her brilliant life?  -  Feb 19, 2008
Z-class drugs - zolpidem, zopiclone and zaleplon - are all non-benzodiazepine hypnotics that are used as an alternative to drugs such as valium. ... Sydney Morning Herald

Brand Names/Synonyms:
Zopiclone is also known by the following brand names and/or synonymsAmoban; Amovane; Imovance; Imovane; Lunesta; Sopivan; ZOPICLONE, 98.5%; Zimovane; Zonisamide; Zopiclona [Inn-Spanish]; Zopiclone; Zopiclone [Ban:Inn:Jan]; Zopiclonum [Inn-Latin]

Drug Category:
Zopiclone is categorized under the following by the FDA: Hypnotics and Sedatives; Anxiolytics sedatives and hypnotics; ATC:N05CF01

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
Not Available

Chemical IUPAC Name:
[8-(5-chloropyridin-2-yl)-7-oxo-2,5,8-triazabicyclo[4.3.0]nona-1,3,5-trien-9-yl]4-methylpiperazine-1-carboxylate

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