benztropine mesylate

This page contains recent news articles, when available, and an overview of benztropine mesylate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

benztropine mesylate (when available)

Pharmacology and use:
Benztropine is an anticholinergic used in the symptomatic treatment of all etiologic groups of parkinsonism and drug induced extrapyramidal reactions (except tardive dyskinesia). Benztropine possesses both anticholinergic and antihistaminic effects, although only the former has been established as therapeutically significant in the management of parkinsonism. Benztropine's anticholinergic activity is about equal to that of atropine. For use as an adjunct in the therapy of all forms of parkinsonism and also for use in the control of extrapyramidal disorders due to neuroleptic drugs.

Mechanism Of Action:
Benztropine is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discriminate between the M1 (cortical or neuronal) and the peripheral muscarinic subtypes (cardiac and glandular). Benztropine partially blocks cholinergic activity in the CNS, which is responsible for the symptoms of Parkinson's disease. It is also thought to increase the availability of dopamine, a brain chemical that is critical in the initiation and smooth control of voluntary muscle movement.

News Articles on Benztropine

Brand Names/Synonyms:
benztropine mesylate is also known by the following brand names and/or synonymsAkitan; Apo-Benztropine; Benzatropina [Inn-Spanish]; Benzatropine; Benzatropinum [Inn-Latin]; Benztropine; Benztropine Mesylate; Benztropinum; Cobrentin; Cogentin; Cogentine; Cogentinol; HSDB 3014; NK 02; NK-02; Pms Benztropine; Tropine Benzohydryl Ether

Drug Category:
benztropine mesylate is categorized under the following by the FDA: Antiparkinson Agents; Muscarinic Antagonists; Antidyskinetics; ATC:N04AC01

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane

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