dalteparin

This page contains recent news articles, when available, and an overview of dalteparin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

dalteparin
(when available)

Pharmacology and use:
Heparin is a highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Heparin is a well known and commonly used anticoagulant which has antithrombotic properties. Heparin is indicated for the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism, and also for the prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin. Heparin inhibits reactions that lead to the clotting of blood and the formation of fibrin clots both in vitro and in vivo. Heparin acts at multiple sites in the normal coagulation system. Small amounts of Heparin in combination with antithrombin III (Heparin cofactor) can inhibit thrombosis by inactivating activated Factor X and inhibiting the conversion of prothrombin to thrombin. Once active thrombosis has developed, larger amounts of Heparin can inhibit further coagulation by inactivating thrombin and preventing the conversion of fibrinogen to fibrin. Heparin also prevents the formation of a stable fibrin clot by inhibiting the activation of the fibrin stabilizing factor. For Anticoagulant therapy in prophylaxis and treatment of venous thrombosis and its extension, for prevention of post-operative deep venous thrombosis and pulmonary embolism , Prevention of clotting in arterial and cardiac surgery.

Mechanism Of Action:
The mechanism of action of Heparin is antithrombin-dependent. It acts mainly by accelerating the rate of the neutralization of certain activated coagulation factors by antithrombin, but other mechanisms may also be involved. The antithrombotic effect of Heparin is well correlated to the inhibition of factor Xa. Heparin interacts with Antithrombin III, Prothrombin and Factor X.

News Articles on Heparin

Low-Molecular-Weight Heparin Reduces Risk of Venous Clots in Patients With ...  -  ‎Dec 10, 2009‎
In the FRAGEM (Chemotherapy With or Without Dalteparin) trial, 123 patients were randomised to receive dalteparin. When the 6 studies that didn't ... DG News

Steve Flecknoe-Brown on heparin guidleines  -  May 20, 2008
It is superior to dalteparin for thromboprophylaxis in association with abdominal surgery. It is equivalent to Clexane in treatment of DVT and ... 6minutes

Dalteparin, 5,000 U Daily, May Be Inadequate Prophylaxis After...  -  May 31, 2005
May 31, 2005 — Dalteparin, 5000 U daily, is inadequate for postoperative deep vein thrombosis (DVT) prophylaxis for women with gynecologic cancer, ... Medscape

Efficacy and Safety of Fixed Low-Dose Dalteparin in Preventing Venous...  -  Feb 14, 2005
Nils Kucher, MD; Alain Leizorovicz, MD; Paul T. Vaitkus, MD, MBA; Alexander T. Cohen, MD; Alexander GG Turpie, MD; Carl-Gustav Olsson, MD; ... Archives of Internal Medicine

DALTEPARIN (Subcutaneous route, Injection route) - dal-TE-pa-rin.(Drug...  -  May 1, 2007
When neuraxial anesthesia (epidural/spinal anesthesia) or spinal puncture is employed, patients anticoagulated or scheduled to be anticoagulated with low ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

Dalteparin can help diabetic foot ulcers.(Dermatologic Therapy)(Clinic...  -  Apr 1, 2007
Dalteparin can help diabetic foot ulcers.(Dermatologic Therapy)(Clinical report) ... find Skin & Allergy News articles. Dalteparin-treated patients have ... Pay-Per-View - Skin & Allergy News - HighBeam Research

Do low-molecular-weight heparins improve the survival of cancer...  -  Jul 26, 2005
To evaluate the effects of the LOW-MOLECULAR-WEIGHT (LMW) HEPARIN dalteparin compared with coumarin derivatives on the survival of cancer patients with ... Nature.com

Dalteparin safe for DVT prophylaxis among those with renal insufficien...  -  Oct 9, 2008
Deep vein thrombosis prophylaxis with the low–molecular-weight heparin dalteparin was not associated with an excessive anticoagulant effect among critically ... HemOncToday

EU Commission approves new use of Arixtra(R) for prevention of venous...  -  Jul 20, 2005
This study demonstrated that ARIXTRA is at least as effective as dalteparin in reducing the risk of total VTE: 4.6 percent of patients on ARIXTRA ... Medical News Today - Medical News Today (press release)

Cancer Treatment; Recent findings from Austria, Japan and the United ...  -  May 10, 2006
Although all the PSAs inhibited VEGF production in KLN205 tumors in vivo and cells in vitro, in LLC tumors and cells only UFH and dalteparin inhibited VEGF ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Low-Molecular-Weight Heparins Do We Have the GUSTO to Identify …  -  Apr 11, 2005
Event rates in the 2 arms were similar, ie, 4.4% for dalteparin-treated patients vs 5.9% for tinzaparin-treated patients (P = .44). ... Archives of Internal Medicine

Daiichi Sankyo Announces Clinical Study Data for Oral Factor Xa...  -  Sep 1, 2008
...reduced the incidence of venous thromboembolism (VTE) compared with dalteparin among patients undergoing elective unilateral hip replacement surgery. ... Genetic Engineering News - Genetic Engineering News (press release)

Nosebleeds and blood thinners (anticoagulant medication)  -  Apr 20, 2007
Blood thinners (anticoagulants) include heparin, warfarin (Coumadin), enoxaparin (Lovenox), dalteparin (Fragmin), and aspirin. ... MSN Health & Fitness

Yeovil doctors involved in cancer tests  -  Jan 22, 2008
Dalteparin - also known as Fragmin - may also have an anti-cancer effect and lead to an improvement in quality of life and survival rates after the lung ... Yeovil Express

Thromboembolism Therapy; Dalteparin based on body weight safe for …  -  Mar 26, 2005
2005 MAR 26 - (NewsRx.com) -- Dosing dalteparin based on actual body weight is safe for the treatment of acute venous thromboembolism in obese patients. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Resort's doctors join lung cancer trial  -  Mar 16, 2008
Dalteparin - also known as Fragmin - may also have an anticancer effect and lead to an improvement in quality of life and survival rates after the lung ... Blackpool Citizen

Thromboembolism Therapy; Dalteparin based on body weight safe for …  -  Mar 21, 2005
2005 MAR 21 - (NewsRx.com) -- Dosing dalteparin based on actual body weight is safe for the treatment of acute venous thromboembolism in obese patients. ... Pay-Per-View - Hematology Week - Factiva, from Dow Jones

London Health Sciences Center; Dalteparin based on body weight safe …  -  Mar 23, 2005
2005 MAR 23 - (NewsRx.com) -- Dosing dalteparin based on actual body weight is safe for the treatment of acute venous thromboembolism in obese patients. ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones

dalteparin sodium Pfizer supplemental approval (deep vein thrombosis)....  -  Sep 5, 2005
During July 2005 Pfizer reported that a supplemental filing of dalteparin sodium (FRAGMIN) was approved in the EU, during April 2005, for the treatment of ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

A leg to stand on: about two million people suffer from deep vein …  -  Sep 17, 2007
Dalteparin sodium is the first LMWH approved in the United States for this indication. The CLOT (Comparison of Low Molecular Weight Heparin vs. ... $4.95 - Drug Topics - ECNext

Merger and Acquisition Scenario  -  Mar 11, 2006
Fragmin (Dalteparin Sodium). Angina. Anticoagulating Agents. Thrombin Inhibitors ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Some cancers need prolonged, high-dose VTE prophylaxis.( …  -  Jul 15, 2008
Because of this experience, Dr. Lee usually treats patients with these cancers and a recent history of VTE with a high-dose regimen of dalteparin for at ... Pay-Per-View - Internal Medicine News - HighBeam Research

Cancer Therapy; Recent findings illuminate research in cancer therapy  -  Apr 12, 2006
Although all the PSAs inhibited VEGF production in KLN205 tumors in vivo and cells in vitro, in LLC tumors and cells only UFH and dalteparin inhibited VEGF ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

FDA approves Arixtra® injection for prevention of venous …  -  May 28, 2005
..."In addition to demonstrating safety profiles comparable to enoxaparin, dalteparin, and unfractioned heparin, ARIXTRA has not had any reported cases of ... i-newswire.com

Merger and Acquisition Scenario  -  Aug 19, 2006
Fragmin (Dalteparin Sodium); E5555; Aciphex (Rabeprazole); AS-3201 (Ranirestat) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

FDA Approves Fondaparinux sodium for Prevention of Venous …  -  May 27, 2005
...as effective as dalteparin in reducing the risk of VTE. In the study, 4.6 percent of patients receiving ARIXTRA experienced a VTE incident versus 6.1 ... RxPG NEWS

Competitors by Product Report  -  Mar 8, 2008
Momenta Pharmaceuticals, Inc. (MNTA) Products:. M-Dalteparin; M-Enoxaparin ... Pfizer Inc. (PFE) Products:. Fragmin (Dalteparin Sodium) ... $75.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Apr 22, 2006
Fragmin (Dalteparin Sodium). Angina. Anticoagulating Agents. Thrombin Inhibitors ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

The Effect of Low-Molecular-Weight Heparin on Microvenous Thrombosis ...  -  Oct 8, 2006
Methods Using male Sprague-Dawley rats, 70 IU/kg of dalteparin sodium (for the treatment group) or isotonic sodium chloride solution (for the control group) ... Archives of Facial Plastic Surgery

Cancer Therapy; Anticoagulants stifle angiogenic growth factor and...  -  Nov 29, 2005
Although all the PSAs inhibited VEGF production in KLN205 tumors in vivo and cells in vitro, in LLC tumors and cells only UFH and dalteparin inhibited VEGF ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Merger and Acquisition Scenario  -  Jan 26, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  May 19, 2007
Fragmin (Dalteparin Sodium); E5555; Ontak (Denileukin Diftitox) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

International Approvals: Xeloda, Fragmin, Onconase  -  Apr 4, 2005
30, Health Canada approved a new indication for dalteparin sodium injection ... Dalteparin was previously approved in Canada for thromboprophylaxis in ... Medscape

Merger and Acquisition Scenario  -  Jan 27, 2007
Fragmin (Dalteparin Sodium); E5555; Aciphex (Rabeprazole); AS-3201 (Ranirestat) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Jun 16, 2007
Fragmin (Dalteparin Sodium); E5555; Ontak (Denileukin Diftitox) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Apr 15, 2006
Buyer (Total: 19). Fragmin (Dalteparin Sodium); E5555; E2051; E5564 ... Fragmin (Dalteparin Sodium). Angina. Anticoagulating Agents. Thrombin Inhibitors ... $250.00 - Revere Reports - Revere

Researchers study prevention of blood clots in cancer patients  -  Oct 8, 2008
They will test whether the drug dalteparin, a low-molecule-weight heparin ... Hospitalized patients routinely are given drugs such as dalteparin to prevent ... RxPG NEWS

How can we best treat and monitor VTE during pregnancy?(CLINICAL …  -  Nov 1, 2005
After 7 days, both groups received prophylactic doses of dalteparin throughout the ... Low molecular weight heparin (dalteparin) for the treatment of venous ... $4.95 - Journal of Family Practice - ECNext

Ximelagatran (Exanta): alternative to warfarin?(Pharmacology Notes)( …  -  Jan 1, 2005
Ximelagatran was also compared with dalteparin and enoxaparin in the METHRO ... Ximelagatran and melagatran compared with dalteparin for prevention of ... Free with registration - Baylor University Medical Center... - AccessMyLibrary.com

Merger and Acquisition Scenario  -  Nov 29, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

LMWH as Bridge Anticoagulation During Warfarin Interruption  -  Apr 15, 2005
Three days before the procedure, LMWH (dalteparin) at a dosage of 100 IU per kg ... The last dose of dalteparin was given no less than 12 hours before the ... AAFP News Now

Preventing venous thromboembolism in your patients at risk.(Clinical ...  -  Feb 1, 2007
The PREVENT study (Prospective Evaluation of Dalteparin Efficacy for Prevention of VTE in Immobilized Patients Trial) results showed that dalteparin, ... Free with registration - Patient Care for the Nurse Practitioner - AccessMyLibrary.com

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Dec 16, 2006
Fragmin (Dalteparin Sodium); E5555; Aciphex (Rabeprazole); AS-3201 (Ranirestat) ... Fragmin (Dalteparin Sodium). Myocardial Infarction (MI) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Nov 22, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Press Release: FDA Approves FRAGMIN(R) as First Low-Molecular- …  -  May 2, 2007
PR Newswire; July 15, 1996 ; 700+ words ... ... surgery prophylaxis, Fragmin 5000 IU (dalteparin ... thrombosis (DVT) with Fragmin can now be tailored ... Pay-Per-View - PR Newswire - HighBeam Research

Low Molecular Weight Heparins Prolong Survival in Cancer Patients  -  Apr 15, 2005
Patients with cancer and acute venous thromboembolism (n=602) were randomized to 6 months treatment with dalteparin alone 200 U/kg for 1 month followed by ... Cancerpage.com

In Randomized Study of Patients with Localized Cancer and DVT, Low …  -  Apr 15, 2005
2003 Jul 10;349(2):146-53), however, showed that dalteparin was more effective in preventing DVT than coumarin derivatives without increasing bleeding risk. ... UroToday International Journal

Does severe renal insufficiency increase the risk of bleeding after …  -  Jul 3, 2006
There were insufficient data to determine the effect of tinzaparin, dalteparin or prophylactic-dose enoxaparin on the likelihood of major bleeding in ... Nature.com

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Apr 7, 2007
Fragmin (Dalteparin Sodium); E5555; Ontak (Denileukin Diftitox) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Non-ST segment elevation acute coronary syndromes: a comprehensive …  -  Oct 1, 2006
Low-molecular weight heparins (LMWH), such as enoxaparin and dalteparin are ... (41) The FRISC 1 trial showed a similar reduction of dalteparin/aspirin to ... Free with registration - Southern Medical Journal - AccessMyLibrary.com

Article: New anticoagulants show promise. - Science News | HighBeam …  -  Dec 17, 2005
Article: Dalteparin for enoxaparin interchange: Chart review shows ... Formulary; October 1, 2001 ; 700+ words ... ... at least as clinically effective as ... Pay-Per-View - Science News - HighBeam Research

Responses: "Anticoagulation Therapy for Venous Thromboembolism"  -  Jan 3, 2005
In the PREVENT Thromboprophylaxis Study, 5% of the patients on placebo and 2.8% of the patients on dalteparin developed symptomatic venous thromboemboli ... Medscape

Drugs trial brings hope for lung cancer patients  -  Feb 18, 2008
Dalteparin, which is sometimes known as Fragmin, may also have an anti-cancer effect and lead to improved quality of life and survival rates post diagnosis, ... Birmingham Post - The Birmingham Post

Non-ST segment elevation acute coronary syndromes: a comprehensive …  -  Oct 1, 2006
Low-molecular weight heparins (LMWH), such as enoxaparin and dalteparin are ... (41) The FRISC 1 trial showed a similar reduction of dalteparin/aspirin to ... $4.95 - Southern Medical Journal - ECNext

Surgical Technology; Out-of-hospital thromboprophylaxis not needed …  -  Apr 12, 2005
..."Possible thromboprophylactic measures included elastic stockings and pre- and postoperative Dalteparin or early ambulation," according to the report. ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Cancer Therapy; Efficacy of warfarin in cancer patients inferior to...  -  Mar 29, 2005
In particular, the LMWH dalteparin (Fragmin; Pfizer; New York, NY), ... A randomized trial of dalteparin has also shown improved response rates and survival ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones

Cancer Therapy; Efficacy of warfarin in cancer patients inferior to...  -  Mar 28, 2005
In particular, the LMWH dalteparin (Fragmin; Pfizer; New York, NY), ... A randomized trial of dalteparin has also shown improved response rates and survival ... Pay-Per-View - Clinical Oncology Week - Factiva, from Dow Jones

Surgical Technology; Out-of-hospital thromboprophylaxis not needed …  -  Apr 16, 2005
..."Possible thromboprophylactic measures included elastic stockings and pre- and postoperative Dalteparin or early ambulation," according to the report. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones

Cancer Therapy; Efficacy of warfarin in cancer patients inferior to...  -  Apr 1, 2005
In particular, the LMWH dalteparin (Fragmin; Pfizer; New York, NY), ... A randomized trial of dalteparin has also shown improved response rates and survival ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Merger and Acquisition Scenario  -  Jul 12, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist); MGi Pharma GPI21016 (Poly ... Fragmin (Dalteparin Sodium). Myocardial Infarction (MI) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Recurrent Pregnancy Loss; Thrombophilia is a common cause of …  -  Apr 7, 2005
..."The first 120 patients were treated with unfractionated heparin at 5000 U every 24 hours subcutaneously, and the last 192 have been treated with Dalteparin ... Pay-Per-View - Women's Health Weekly - Factiva, from Dow Jones

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Dec 13, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist); MGi Pharma GPI21016 (Poly ... Fragmin (Dalteparin Sodium). Myocardial Infarction (MI) ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Mar 8, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Dec 27, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Merger and Acquisition Scenario  -  Jan 26, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Press Release: Daiichi Sankyo Announces Clinical Study Data for Oral ...  -  Sep 2, 2008
Study Result Details VTE incidence (%) Bleeding occurrence*** (%) Dalteparin 43.8 [35.5-52.3]# 0 [0-2.1] DU-176b 15mg 28.2 [21.6-35.6]* 1.6 [0.3-4.5] 30mg ... Pay-Per-View - PR Newswire - HighBeam Research

Competitors by Product Report  -  Jun 7, 2008
Eisai Co., Ltd (ADR) (ESALY) Products:. Fragmin (Dalteparin Sodium) ... Encysive Pharmaceuticals Argatroban; Fragmin (Dalteparin Sodium) ... $75.00 - Revere Reports - Revere

Competitors by Product Report  -  Jun 7, 2008
Eisai Co., Ltd (ADR) (ESALY) Products:. Fragmin (Dalteparin Sodium) ... Encysive Pharmaceuticals Argatroban; Fragmin (Dalteparin Sodium) ... $75.00 - Revere - Alacra Store

Merger and Acquisition Scenario  -  Sep 6, 2008
Fragmin (Dalteparin Sodium); E5555 (Thrombin Receptor Agonist) ... Fragmin (Dalteparin Sodium). Phase I/Phase II Clinical Stage Products ... $250.00 - Revere Reports - Revere

Fixed-Dose Unfractionated Heparin vs Low-Molecular-Weight Heparin for...  -  Jan 17, 2007
Dalteparin is not FDA-approved and has limited published data demonstrating efficacy against intravenous unfractionated heparin. ... Journal of American Medical Association - Journal of American Medical Association...

Unfractionated Heparin: Effective Therapy at Bargain Price  -  Aug 22, 2006
Explain to interested patients that current recommendations favor the use of drugs such as Lovenox (enoxaparin) or Fragmin (dalteparin) for treatment of ... MedPage Today

Short- and long-term efficacy of aspirin and clopidogrel for …  -  Dec 3, 2007
Results: At 30 days, we observed 216 ± 270 mg of thrombus for the no anticoagulation group, 53 ± 91 mg for the dalteparin group, 33 ± 23 mg for the aspirin ... The Journal of Thoracic and Cardiovascul...

Here are first guidelines for VTE in cancer patients.(RX CARE)(venous...  -  May 8, 2006
Inpatient prophylactic anticoagulation therapy Brand name/ Anticoagulant Dosage manufacturer dalteparin 5000 units SC daily Fragmin, Pfizer enoxaparin 40-mg ... Free with registration - Drug Topics - AccessMyLibrary.com

Guidelines Updated for Prevention of DVT and PE Linked With …  -  Aug 9, 2007
Subcutaneous low-molecular-weight heparin (LMWH; dalteparin 2500 ... Subcutaneous LMWH (dalteparin 5000 antifactor-Xa units or enoxaparin 40 mg), ... Medscape

NO.1 경제í?¬í„¸ :: 매ì?¼ê²½ì œ  -  Sep 2, 2008
...임�시험중� 경구용 Factor Xa 억제제� DU-176b가 긴급� 요하지 는 �측성 히프 대치수술(elective unilateral hip replacement surgery) 환�들�게서 dalteparin ... 매�경제

Factor Xa inhibitors: future therapeutic directions in the prophylaxis...  -  Oct 1, 2006
...fondaparinux 2.5 mg or dalteparin 5000 units once daily for 5 to 9 days. ... as dalteparin in preventing VTE among high-risk general surgery patients. ... Free with registration - Formulary - AccessMyLibrary.com

International Approvals: Tarceva, Arixtra, 1D09C3  -  Jul 18, 2005
Rates of major bleeding associated with treatment were comparable between the fondaparinux sodium and dalteparin groups (3.4% vs 2.4%). ... Medscape

Daiichi Sankyo Reports Positive Data for Anticoagulant Drug  -  Sep 3, 2008
The data showed that DU-176b reduced the incidence of venous thromboembolism compared with dalteparin among patients undergoing elective unilateral hip ... RedOrbit

New guidelines target DVT in cancer patients.(Cardiovascular,...  -  May 15, 2005
The dalteparin group had 52% fewer recurrent clots over the 6-month study period, with no significant increase in the incidence of bleeding, Dr. Jahanzeb ... Free with registration - Internal Medicine News - AccessMyLibrary.com

Drug trial is world's largest  -  Jan 11, 2008
Dalteparin - also known as Fragmin - may also have an anti-carcinogenic effect and lead to an improvement in quality of life and survival rates after the ... Watford Observer

Stoke Mandeville patients taking part in cancer trials  -  Jan 7, 2008
Dalteparin, also known as Fragmin, may also have an anticancer effect and lead to an improvement in quality of life and survival rates after the lung cancer ... Aylesbury Today

DVT prophylaxis following orthopedic surgery.(Drug Update)  -  Feb 1, 2005
Safe during lactation. dalteparin no generic 5000 Available in trade formulation ... Consultant to Pfizer Inc., manufacturer of dalteparin sodium injection. ... Free with registration - Family Practice News - AccessMyLibrary.com

Researchers look to improve lung cancer treatment  -  Apr 14, 2008
Dalteparin - also known as Fragmin - may also have an anticancer effect and lead to an improvement in quality of life and survival rates after the lung ... Cancerfacts.com

Factor Xa inhibitors: future therapeutic directions in the prophylaxis...  -  Oct 1, 2006
...(n=2048) scheduled for high-risk major abdominal surgery received either fondaparinux 2.5 mg or dalteparin 5000 units once daily for 5 to 9 days. ... Free with registration - Managed Healthcare Executive - AccessMyLibrary.com

Anticoagulation in non-ST-Segment elevation acute coronary syndromes ...  -  Sep 1, 2007
In the FRIC (Fragmin in Unstable Coronary Artery Disease) trial, which compared UFH to dalteparin in NSTE ACS, the efficacy and safety of dalteparin were ... Free with registration - Formulary - AccessMyLibrary.com

Daiichi Sankyo 公布å?£æœ?Factor Xa 抑制劑DU-176b 的臨床研究數據  -  Sep 2, 2008
...今天在�洲心臟病學年會(Annual Congress of the European Society of Cardiology) 上 公布的數據顯示,與dalteparin(��素)相比,研究用��Factor Xa 抑制 ... 財�網

Daiichi Sankyo Umumkan data Studi Klinis Zat Penghambat Faktor Xa …  -  Sep 2, 2008
...pengaruh thromboembolisme urat nadi (VTE) dibandingkan dengan dalteparin pada pasien yang sedang menjalani proses pembedahan pinggul unilateral elektif. ... ANTARA

Using low molecular weight heparins as "bridging anticoagulant …  -  Apr 1, 2005
The following LMWH preparations and dose regimens can be used: dalteparin, 200 IU/kg once daily or 100 IU/kg twice daily; enoxaparin, 1.5 mg/kg once daily ... $4.95 - Journal of Respiratory Diseases - ECNext

Review: LMWH safe, effective in pregnancy.(Obstetrics) | Article from...  -  Jan 1, 2005
LMWHs have a relatively high molecular weight ... with prosthetic heart valves. The three available LMWH products, dalteparin (Fragmin), enoxaparin (Lovenox ... Pay-Per-View - OB GYN News - HighBeam Research

Drug Development; Synthetic Heparin market potential boosted by US …  -  Jul 1, 2005
In the study, 4.6% of patients receiving Arixtra experienced a VTE incident compared to 6.1% of patients on dalteparin. Arixtra is already approved in ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

Momenta Pharmaceuticals Reports Financial Results for the First...  -  May 10, 2005
We remain on schedule to file an ANDA for M-Dalteparin and an IND for M118 with the FDA in mid-2006," continued Mr. Crane. ... $4.95 - PR Newswire - ECNext

Brand Names/Synonyms:
dalteparin is also known by the following brand names and/or synonyms000 Units in Sodium Chloride 0.45%; 000 Units in Sodium Chloride 0.9%; Alpha-Heparin; Ariven; Arteven; Bemiparin; CY 216; Calcilean; Calciparine; Certoparin; Clexane; Clivarin; Clivarine; Cy 222; Dalteparin; Depo-Heparin; Enoxaparin; Enoxaparin Sodium; Eparina [Dcit]; FR 860; Fluxum; Fragmin A; Fragmin B; Fraxiparin; HSDB 3094; Hed-Heparin; Hepalean; Heparin; Heparin Cy 216; Heparin Leo; Heparin Lock Flush; Heparin Sodium; Heparin Sodium Preservative Free; Heparin Sodium Salt; Heparin Sulfate; Heparinate; Heparinic Acid; Hepathrom; KB 101; Leparan; Lipo-Hepin; Liquaemin; Liquaemin Sodium; Liquemin; Low Molecular Weight Heparin Sodium; Multiparin; Novoheparin; OP 386; OP 622; Pabyrin; Parnaparin; Parvoparin; Pularin; Reviparin; Sandoparin; Sodium Heparin; Sublingula; Thromboliquine; Vetren; Vitrum Ab

Drug Category:
dalteparin is categorized under the following by the FDA: Fibrinolytic Agents; Anticoagulants; Heparins; ATC:B01AB01; ATC:C05BA01; ATC:C05BA03; ATC:S01XA09; ATC:S01XA14

Dosage Forms:
Solution for subcutaneous injection, intravenous injection, or intravenous infusion

Absorption:
Some oral absorption but lack of anticoagulant effect. Rapidly taken up by endothelial cells with remainder bound to plasma proteins.

Interactions:
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Chemical IUPAC Name:
6-[5-acetylamino-4,6-dihydroxy-2-(sulfooxymethyl)tetrahydropyran-3-yl]oxy-3-[5-(6-carboxy-4,5-dihydroxy-3-sulfooxy-tetrahydropyran-2-yl)oxy-6-(hydroxymethyl)-3-sulfoamino-4-sulfooxy-tetrahydropyran-2-yl]oxy-4-hydroxy-5-sulfooxy-tetrahydropyran-2-carboxylicacid





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