|
 |
fludarabine phosphateThis page contains recent news articles, when available, and an overview of fludarabine phosphate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: fludarabine phosphate (when available) Fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia. It acts at DNA polymerase alpha, ribonucleotide reductase and DNA primase, results in the inhibition of DNA synthesis, and destroys the cancer cells. For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen Mechanism Of Action: Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite appears to act by inhibiting DNA polymerase alpha, ribonucleotide reductase and DNA primase, thus inhibiting DNA synthesis. The mechanism of action of this antimetabolite is not completely characterized and may be multi-faceted. News Articles on Fludarabine Genzyme Reports Third-Quarter Financial Results - Oct 22, 2009 This increase was driven by new revenue from Leukine ® (sargramostim), Campath ® (alemtuzumab) and Fludara ® (fludarabine phosphate), following the closing ... Business Wire (press release) Fludarabine phosphate and melphalan: a reduced intensity conditioning... - Jan 23, 2006 Correspondence: Dr RK Dasgupta, Department of Haematology, University Hospital Aintree, Longmoor Lane, Liverpool, L9 7AL UK. ... Nature.com Abraxis BioScience gets US FDA approval for generic version of Bayer's... - Oct 17, 2007 The drug, based on the active compound fludarabine phosphate, was cleared for treating a chronic form of leukemia in adults, Abraxis said in a statement. ... Forbes … ; Non-Hodgkin lymphoma treated by oral fludarabine phosphate - Mar 28, 2006 Patients received fludarabine phosphate orally for 5 days, ... "Oral fludarabine phosphate is safe and effective for relapsed patients with indolent B-NHL. ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones Press Release: Xanthus Pharmaceuticals Expands Oncology Pipeline … - Oct 3, 2006 Data suggest that oral fludarabine phosphate is effective and provides ... evaluate the ... Article: Oral Fludarabine Phosphate Equally Effective and ... ... Pay-Per-View - PR Newswire - HighBeam Research Study Results Published in Journal of Clinical Oncology Show FluCam … - Oct 21, 2005 Fludara (fludarabine phosphate) is approved as a first-line and second- line therapy in Europe for the treatment of B-CLL. It also is being investigated as ... biotech-intelligence.com Antisoma receives FDA approval for oral fludarabine, plans … - Dec 19, 2008 The FDA has approved fludarabine phosphate film-coated tablets as a single agent for the treatment of adult patients with B-cell chronic lymphocytic ... Genetic Engineering News - Genetic Engineering News (press release) F-ara-A pharmacokinetics during reduced-intensity conditioning... - Jan 8, 2007 Central nervous system toxicity of fludarabine phosphate. ... Pharmacology of fludarabine phosphate after a phase I/II trial by a loading bolus and ... Nature.com Press Release: Study Results Published in Journal of Clinical... - Oct 21, 2005 Article: Fludarabine phosphate and alemtuzumab show promise in treating ... Cancer Weekly; June 24, 2003 ; 606 words ... ... for the treatment of patients ... Pay-Per-View - PR Newswire Europe - HighBeam Research International Approvals: Pariet, Fludara Oral, Sandoglobulin NF Liquid - Mar 2, 2007 In the United States, fludarabine phosphate is available only as a 50-mg/vial formulation for IV infusion for the second-line treatment of B-cell chronic ... Medscape Custom synthesis of APIs: researchers and process chemists share … - Jan 1, 2008 Ash Stevens is the contract manufacturer of fludarabine phosphate, the API in Fludara. While both of these agents were subsequently approved as drugs by ... $9.94 - Pharmaceutical Technology - Alacra Store Abraxis Pharmaceutical Products, Schaumburg, Ill., (847) 413-2075,... - Dec 10, 2007 Fludarabine phosphate will be marketed in two forms. ... The liquid version is the equivalent of fludarabine phosphate for injection marketed by Teva ... Free with registration - Drug Topics - AccessMyLibrary.com Abraxis gains two FDA OKs for fludarabine. - Oct 22, 2007 The liquid version of fludarabine, which is the equivalent of fludarabine phosphate for injection marketed by Teva Parenteral Medicines, will be packaged in ... $4.95 - Pharma Marketletter - ECNext … одобрение FDA на маркетинг Fludarabine phosphate в двух форма? - Oct 17, 2007 Ð?мериканÑ?каÑ? компаниÑ? Abraxis Pharmaceutical Products (APP) получила разрешениÑ? УправлениÑ? по контролю за продовольÑ?твием и медикаментами СШÐ? (FDA) на ... ФармацевтичеÑ?кий веÑ?тник Allogeneic blood SCT for children with Hurler's syndrome: results... - Oct 13, 2008 Fludarabine phosphate: a synthetic purine antimetabolite with significant activity against lymphoid malignancies. J Clin Oncol 1991; 9: 175–188. ... Nature.com Article: SUNLIGHT MAY HAVE BENEFITS FOR VICTIMS OF SKIN … - Feb 2, 2005 ...aldesleukin Phase II Nonmelanomatous Drug: cyclophosphamide Skin Cancer Drug: filgrastim Drug: fludarabine phosphate Drug: therapeutic ... ... Pay-Per-View - Cincinnati Post - HighBeam Research Xanthus Receives Orphan Drug Designation for Oral Fludarabine for the... - Jan 3, 2008 ...today announced that the FDA has granted Orphan Drug Designation to fludarabine phosphate oral tablets for the treatment of B-cell chronic lymphocytic ... Free with registration - Business Wire - AccessMyLibrary.com Xanthus Announces Oral Fludarabine NDA Accepted for Review by US … - Jan 22, 2008 ...today announced that its New Drug Application (NDA) for fludarabine phosphate oral tablets (oral fludarabine) was accepted for filing by the US Food and ... Genetic Engineering News - Genetic Engineering News (press release) Genzyme Launches New Diagnostic Test for Common Blood Cancer. - Jul 27, 2006 ...monoclonal antibody approved for the treatment of B-CLL in patients who have failed both alkylating agents and fludarabine phosphate treatment. ... Free with registration - PR Newswire - AccessMyLibrary.com Genzyme Launches Minimal Residual Disease Test for Common … - Jul 19, 2005 ...for B-CLL and is the first product with proven efficacy in B-CLL patients who have failed both alkylating agents and fludarabine phosphate treatment. ... RedOrbit Xanthus Receives Orphan Drug Designation for Oral Fludarabine for the... - Mar 1, 2008 ...today announced that the FDA has granted Orphan Drug Designation to fludarabine phosphate oral tablets for the treatment of B-cell chronic lymphocytic ... Euroinvestor New Phase III Study Shows Strong Efficacy and Favorable Safety... - Jun 6, 2006 ...therapy and the first product with proven efficacy in CLL patients who have failed both alkylating agents and Fludara (fludarabine phosphate) treatment. ... presseportal.de MabCampath effective in B-Cell CLL, says trial.(Leukemia drugs... - Oct 31, 2005 ...developed by USA-based group Genzyme Oncology and Fludara (fludarabine phosphate) and distributed in the USA by Berlex (a subsidiary of Schering AG), ... Free with registration - Pharma Marketletter - AccessMyLibrary.com Article: TANNING SALONS INCREASE RISK FOR GETTING CANCER.( … - Jul 2, 2008 ...aldesleukin Phase II Nonmelanomatous Drug: cyclophosphamide Skin Cancer Drug: filgrastim Drug: fludarabine phosphate Drug: therapeutic ... ... Pay-Per-View - Post-Standard - HighBeam Research New Phase III Study Shows Strong Efficacy and Favorable Safety... - Jun 5, 2006 ...therapy and the first product with proven efficacy in CLL patients who have failed both alkylating agents and Fludara (fludarabine phosphate) treatment. ... Free with registration - PR Newswire - AccessMyLibrary.com Special Concern About Squamous Cell Carcinoma of the Scalp in Organ … - Jul 15, 2005 6 A case of severe exacerbation of SCC of the scalp was observed in a patient with chronic lymphocytic leukemia who was receiving fludarabine phosphate. ... Archives of Dermatology Nektar Appoints Howard W. Robin President and CEO - Jan 8, 2007 ...multiple sclerosis and Fludara(R) (fludarabine phosphate) for chronic lymphocytic leukemia, generating annual global sales in excess of $800 million. ... Genetic Engineering News - Genetic Engineering News (press release) Press Release: Sagent Pharmaceuticals Launches Ceftriaxone, USP, and … - Jul 16, 2008 Phosphate for Injection, USP Fludarabine phosphate for injection, USP (generic equivalent ... information. About Sagent Pharmaceuticals, Inc. Sagent ... ... Pay-Per-View - PR Newswire - HighBeam Research Pro-Pharmaceuticals Collaborates With Chemwerth to Scale-Up … - Feb 20, 2007 Cisplatin USP, Doxorubicin HCl USP, Epirubicin HCl EP, Etoposide USP, Fludarabine Phosphate, Gemcitabine HCl USP, Ifosfamide USP, Irinotecan HCl 3H2O, ... RedOrbit Chronic Lymphocytic Leukemia; Combination of MabCampath and … - Jan 11, 2005 ...combination MabCampath (alemtuzumab) and Fludara (fludarabine phosphate) therapy (FluCam) presented at the American Society of Hematology meeting (ASH) ... Pay-Per-View - Life Science Weekly - Factiva, from Dow Jones Pro-Pharmaceuticals Collaborates with Chemwerth. - Feb 21, 2007 Cisplatin USP, Doxorubicin HCl USP, Epirubicin HCl EP, Etoposide USP, Fludarabine Phosphate, Gemcitabine HCl USP, Ifosfamide USP, Irinotecan HCl 3H2O, ... Free with registration - M2 Presswire - AccessMyLibrary.com Ash Stevens Inc. Awarded Two Contracts From the National Cancer … - Oct 2, 2006 In fact, the two organizations partnered to develop Fludarabine Phosphate, a treatment for certain types of leukemia, and 5-Azacitidine, a drug to treat ... $4.95 - PR Newswire - ECNext Chronic Lymphocytic Leukemia; Combination of MabCampath and … - Jan 14, 2005 ...combination MabCampath (alemtuzumab) and Fludara (fludarabine phosphate) therapy (FluCam) presented at the American Society of Hematology meeting (ASH) ... Pay-Per-View - Genomics & Genetics Weekly - Factiva, from Dow Jones Article: indolent - The Oxford American Writers Thesaurus | HighBeam ... - Jul 12, 2006 Oral Fludarabine for Indolent NHL: A Phase II Trial Abstract & ... oral fludarabine phosphate in relapsed indolent B-cell non-Hodgkin?s lymphoma ... Pay-Per-View - Oxford American Writers Thesaurus - HighBeam Research Chemotherapy and total-body irradiation followed by autologous … - Jun 1, 2007 Drug: cyclophosphamide Skin Cancer Drug: filgrastim Drug: fludarabine phosphate Drug: therapeutic tumor infiltrating lymphocytes Procedure: autologous ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com University of Ulm; Analysis shows benefit of MabCampath in leukemia - Jan 12, 2005 ...for CLL and the first drug with proven efficacy in CLL patients who have failed both alkylating agents and Fludara (fludarabine phosphate) treatment. ... Pay-Per-View - Biotech Week - Factiva, from Dow Jones Clinical Alerts: SPC Changes. - Mar 1, 2008 Fludara tablets (fludarabine phosphate) Statement added that drug is not recommended for use in children. Deltacortril enteric-coated tablets (prednisolone) ... $9.94 - Chemist & Druggist - Alacra Store Bayer's oral Fludara gets MHLW approval.(Bayer Schering Pharma)( … - Feb 5, 2007 Fludara (fludarabine phosphate), has received Japanese marketing approval for use in the treatment of non-Hodgkin's lymphoma and mantle cell lymphoma. ... Free with registration - Pharma Marketletter - AccessMyLibrary.com Leukemia; Analysis shows benefit of MabCampath in leukemia - Jan 15, 2005 ...for CLL and the first drug with proven efficacy in CLL patients who have failed both alkylating agents and Fludara (fludarabine phosphate) treatment. ... Pay-Per-View - Obesity, Fitness & Wellness Week - Factiva, from Dow Jones Chemotherapy and total-body irradiation followed by autologous … - Aug 1, 2007 Drug: cyclophosphamide Skin Cancer Drug: filgrastim Drug: fludarabine phosphate Drug: therapeutic tumor infiltrating lymphocytes Procedure: autologous ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com Press Release: REVLIMID(R)(lenalidomide) Study In Chronic … - Jun 7, 2005 ...in the October issue of the Journal of Clinical Oncology, combination therapy with MabCampath (alemtuzumab) and Fludara (fludarabine phosphate) ... Pay-Per-View - PR Newswire Europe - HighBeam Research Chemotherapy followed by autologous natural killer cells and aldesleuk... - Jun 1, 2007 Condition Intervention Phase Kidney Cancer Drug: aldesleukin Phase II Melanoma (Skin) Drug: cyclophosphamide Nonmelanomatous Drug: fludarabine phosphate ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com Press Release: Genmab to Present Interim Results in Phase I/II... - Aug 22, 2005 ...in the October issue of the Journal of Clinical Oncology, combination therapy with MabCampath (alemtuzumab) and Fludara (fludarabine phosphate) ... Pay-Per-View - PR Newswire Europe - HighBeam Research Chemotherapy plus biological therapy in treating patients with... - May 1, 2007 ...aldesleukin Drug: cyclophosphamide Drug: filgrastim Drug: fludarabine phosphate Drug: gp100 antigen Drug: incomplete Freund's adjuvant Drug: therapeutic ... Free with registration - Journal of Drugs in Dermatology - AccessMyLibrary.com BERLEX PUBLISHES LEUKEMIA STUDY RESULTS - Oct 25, 2005 ...combination therapy with Berlex Laboratories' MabCampath (alemtuzumab) and Fludara (fludarabine phosphate) is effective in patients with B-cell chronic ... Pay-Per-View - FDAnews Drug Pipeline Alert - Factiva, from Dow Jones Precautions on the use of barium sulfate revised. - Dec 12, 2005 ...sulfate (as X-ray contrast medium, seven manufacturers), fludarabine phosphate (Nihon Schering), and twelve other revisions, including bepridil HCl. ... Pay-Per-View - Pharma Japan - Factiva, from Dow Jones Press Release: REVLIMID(R) Clinical Results as Oral Treatment … - Dec 12, 2005 ...in the October issue of the Journal of Clinical Oncology, combination therapy with MabCampath (alemtuzumab) and Fludara (fludarabine phosphate) ... Pay-Per-View - PR Newswire Europe - HighBeam Research Article: China Recalls Tainted Leukemia Drugs - AP Online | HighBeam ... - Sep 16, 2007 ...developed by USA-based group Genzyme Oncology and Fludara (fludarabine phosphate) and distributed in the USA by Berlex (a subsidiary of Schering AG), is ... Pay-Per-View - Associated Press/AP Online - HighBeam Research Chemotherapy and total-body irradiation followed by autologous … - Aug 1, 2007 Drug: cyclophosphamide Skin Cancer Drug: filgrastim Drug: fludarabine phosphate Drug: therapeutic tumor infiltrating lymphocytes Procedure: autologous ... $4.95 - Journal of Drugs in Dermatology - ECNext Chemotherapy and total-body irradiation followed by autologous … - Jun 1, 2007 Drug: cyclophosphamide Skin Cancer Drug: filgrastim Drug: fludarabine phosphate Drug: therapeutic tumor infiltrating lymphocytes Procedure: autologous ... $4.95 - Journal of Drugs in Dermatology - ECNext Chemotherapy followed by autologous natural killer cells and aldesleuk... - Jun 1, 2007 Condition Intervention Phase Kidney Cancer Drug: aldesleukin Phase II Melanoma (Skin) Drug: cyclophosphamide Nonmelanomatous Drug: fludarabine phosphate ... $4.95 - Journal of Drugs in Dermatology - ECNext Article: China Recalls Tainted Leukemia Drugs - AP Online | HighBeam ... - Sep 16, 2007 ...developed by USA-based group Genzyme Oncology and Fludara (fludarabine phosphate) and distributed in the USA by Berlex (a subsidiary of Schering AG), is ... Pay-Per-View - Associated Press/AP Online - HighBeam Research Article: China Recalls Tainted Leukemia Drugs - AP Online | HighBeam ... - Sep 16, 2007 ...developed by USA-based group Genzyme Oncology and Fludara (fludarabine phosphate) and distributed in the USA by Berlex (a subsidiary of Schering AG), is ... Pay-Per-View - Associated Press/AP Online - HighBeam Research Bayer Schering Pharma integrated in Japan, ranking 18th on the … - Aug 20, 2007 ...which was filed with the Japanese authorities in June 2006, in addition to having launched the malignant lymphoma drug Fludara (fludarabine phosphate), ... $4.95 - Pharma Marketletter - ECNext Press Release: Final Data from Phase III Study Show Single-Agent … - Dec 11, 2006 Article: Study Demonstrates Oral Fludarabine Phosphate and ... PR Newswire; December 8, 2003 ; 700+ words ... ... Meeting and Exposition showed that CLL ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Three Studies Presented at the American Society of … - Dec 9, 2008 Article: Study Demonstrates Oral Fludarabine Phosphate and ... PR Newswire; December 8, 2003 ; 700+ words ... ... Meeting and Exposition showed that CLL ... Pay-Per-View - PR Newswire - HighBeam Research 복지부 분류코드: 421(í•ì•…ì„±ì¢…ì–‘ì œ) - Apr 9, 2007 Fludarabine phosphate(2F-Ara-AMP)ì?€ 수용성ì?˜ prodrug으로, 혈장ì—?ì„œ 2-fluoro-ara-A ë¡œ 탈ì?¸ì‚°í™”ë?˜ê³ 세í?¬ ë‚´ì—? ìœ ìž…ë?œ 후 deoxycytidine kinaseì—? ì?˜í•´ ì?¸ì‚°í™”ë?˜ì–´ ... ì•½ì—…ì‹ ë¬¸ Press Release: KineMed Reports Data Demonstrating New Insights into … - Mar 1, 2005 Article: Combination of Alemtuzumab and Fludarabine Phosphate Shown to Be ... PR Newswire; December 10, 2002 ; 700+ words ... ... refractory B-cell chronic ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Data from Phase 3 Trial of Genasense(R) Confirm … - Sep 19, 2005 Article: Study Demonstrates Oral Fludarabine Phosphate and ... PR Newswire; December 8, 2003 ; 700+ words ... ... Meeting and Exposition showed that CLL ... Pay-Per-View - PR Newswire - HighBeam Research Press Release: Pharmacyclics Announces Presentation and Publication … - Dec 12, 2005 Article: Study Demonstrates Oral Fludarabine Phosphate and ... PR Newswire; December 8, 2003 ; 700+ words ... ... Meeting and Exposition showed that CLL ... Pay-Per-View - PR Newswire - HighBeam Research Brand Names/Synonyms: fludarabine phosphate is also known by the following brand names and/or synonymsFAMP; Fludara; Fludarabine; Fludarabine 5'-Monophosphate; Fludarabine Monophosphate; Fludarabine Phosphate; Fludarabine Phosphate [Usan:Ban]; Fludura Drug Category: fludarabine phosphate is categorized under the following by the FDA: Immunosuppressive Agents; Antimetabolites; Antineoplastic Agents; ATC:L01BB05 Dosage Forms: TABLET; POWDER FOR SOLUTION; IV Solution Absorption: Not Available Interactions: [an error occurred while processing this directive] Chemical IUPAC Name: [5-(6-amino-2-fluoro-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid |
|
Health Home | Conditions | Cancer | Medications | Surgery | Vaccines The Cancer News Network
COPYRIGHT 2009 CANCERNEWSNETWORK | Privacy |