gemcitabine HCl

This page contains recent news articles, when available, and an overview of gemcitabine HCl but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

gemcitabine HCl
(when available)

Pharmacology and use:
Gemcitabine is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (or DNA synthesis phase of the cell cycle), stopping normal development and division. Gemcitabine blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Gemcitabine blocks the incorporation of the thymidine nucleotide into the DNA strand. For the first-line treatment of patients with metastatic breast cancer , locally advanced (Stage IIIA or IIIB), or metastatic (Stage IV) non-small cell lung cancer and as first-line treatment for patients with adenocarcinoma of the pancreas

Mechanism Of Action:
Gemcitabine inhibits thymidylate synthetase, leading to inhibition of DNA synthesis and cell death. Gemcitabine is a prodrug so activity occurs as a result of intracellular conversion to two active metabolites, gemcitabine diphosphate and gemcitabine triphosphate by deoxycitidine kinase. Gemcitabine diphosphate inhibits ribonucleotide reductase, the enzyme responsible for catalyzing synthesis of deoxynucleoside triphosphates required for DNA synthesis. Gemcitabine triphosphate (diflurorodeoxycytidine triphosphate) competes with endogenous deoxynucleoside triphosphates for incorporation into DNA.

News Articles on Gemcitabine

Shilpa Medicare gets Korean regulatory nod for cancer drug  -  Jan 16, 2008
The company has already filed EDMF for Gemcitabine HCL in 27 European countries. Gemcitabine HCL is going off the patent soon and the global market size in ... सिफी - सिफी

Shilpa Medicare gets suitability certificate for Oxaliplatin EP  -  Mar 7, 2008
The company has already filed EDMF for Gemcitabine HCL in 27 European countries. Gemcitabine HCL is going off the patent soon and the global market size in ... Economic Times

Press Release: Lilly Oncology Prepares for Strong Showing at ASCO …  -  May 23, 2006
Administration has granted approval of Gemzar(R) (gemcitabine HCl ... second ... 2002 New research findings report that Gemzar(R) (gemcitabine HCl) in ... Pay-Per-View - PR Newswire - HighBeam Research

LILLY (ELI) & COMPANY - LLY Targeted Agent Shows Promise.  -  May 17, 2005
...of innovation for the group, which has produced GemzarA' (gemcitabine HCl) and AlimtaA' (pemetrexed), two of the world's leading chemotherapy agents. ... Free with registration - PR Newswire UK Disclose - AccessMyLibrary.com

Press Release: LILLY (ELI) & COMPANY - Gemzar Provides Significant …  -  May 17, 2005
World Health Organization 3 April 2003; Accessed 26 April 2005 http://www.who.int/ mediacentre/news/releases/2003/pr27/en/ GemzarA' (gemcitabine HCl, ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

FDA Approvals: Emend, Gemzar, Avastin  -  Jul 21, 2006
On July 14, the FDA approved a new indication for gemcitabine HCl injection (Gemzar, made by Eli Lilly and Company), allowing its use in combination with ... Medscape

Making Science Personal: Lilly Oncology to Unveil 76 Studies at ASCO ...  -  May 23, 2007
The company will present important data on GEMZAR(R) (gemcitabine HCl for injection), ALIMTA(R) (pemetrexed for injection), and enzastaurin, ... Free with registration - PR Newswire - AccessMyLibrary.com

Press Release: New Study Results Demonstrate Clinical Effectiveness...  -  May 16, 2005
Article: Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for ... PR Newswire; May 31, 2009 ; 700+ words ... ... adenocarcinoma of the pancreas. ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Lilly Oncology Prepares for Strong Showing at ASCO …  -  May 23, 2006
Key Lilly Abstracts for ASCO 2006: -- GEMZAR(R) (gemcitabine HCl) - Title: Expression profiles can predict chemotherapy response in breast cancer patients, ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: New Data Show Gemzar(R)-Based Combination …  -  May 17, 2005
Article: Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for ... ... Important Safety Information for GEMZAR (gemcitabine HCl for injection) GEMZAR is ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Making Science Personal: Lilly Oncology to Unveil 76 …  -  May 23, 2007
The company will present important data on GEMZAR(R) (gemcitabine HCl for injection), ALIMTA(R) (pemetrexed for injection), and enzastaurin, ... Pay-Per-View - PR Newswire - HighBeam Research

International Approvals: NuvaRing, MabThera, Gemzar  -  Jul 17, 2006
On July 10, Japan's Ministry of Health, Labor, and Welfare (MHLW) approved a new indication for gemcitabine HCl injection (Gemzar, made by Eli Lilly Japan), ... Medscape

Press Release: LILLY (ELI) & COMPANY - LLY Targeted Agent Shows …  -  May 17, 2005
...of innovation for the group, which has produced GemzarA' (gemcitabine HCl) and AlimtaA' (pemetrexed), two of the world's leading chemotherapy agents. ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

Lilly Oncology Prepares for Strong Showing at ASCO 2006; Targets …  -  May 23, 2006
Product Description: Gemzar(R) (gemcitabine HCl) is an anticancer drug that interferes with the processes of DNA production; by doing so, Gemzar prevents ... Free with registration - PR Newswire - AccessMyLibrary.com

FDA Approvals: Clobex and Tarceva/Gemzar  -  Nov 10, 2005
...and erlotinib plus gemcitabine HCl combination therapy for the ... Inc.), allowing its use in combination with gemcitabine HCl (Gemzar injection, ... Medscape

Press Release: LILLY (ELI) & COMPANY - ALIMTA Receives EU …  -  Apr 11, 2008
The approval in first-line NSCLC is based on a Phase III randomized study that evaluated pemetrexed plus cisplatin versus GEMZARA[R] (gemcitabine HCl for ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

Press Release: LILLY (ELI) & COMPANY - New Study on Gemzar. - PR …  -  May 17, 2005
Gemzar(R) (gemcitabine HCl, Lilly) Taxol(R) (paclitaxel, Bristol-Myers Squibb) Xeloda(R) (capecitabine, Roche) Taxotere(R) (docetaxel, Sanofi-Aventis) (1) ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

Pro-Pharmaceuticals Collaborates With Chemwerth to Scale-Up …  -  Feb 20, 2007
Etoposide USP, Fludarabine Phosphate, Gemcitabine HCl USP, Ifosfamide USP, Irinotecan HCl 3H2O, Mitoxantrone HCl USP/PhEur and Thiotepa USP. ... RedOrbit

Pro-Pharmaceuticals Collaborates with Chemwerth.  -  Feb 21, 2007
Etoposide USP, Fludarabine Phosphate, Gemcitabine HCl USP, Ifosfamide USP, Irinotecan HCl 3H2O, Mitoxantrone HCl USP/PhEur and Thiotepa USP. ... Free with registration - M2 Presswire - AccessMyLibrary.com

Eli Lilly Net Income Down Almost 20 Percent After Acquisitions  -  Aug 1, 2007
...up 9 percent to $1.213 billion; Cymbalta (duloxetine HCl), up 67 percent to $519.5 million; Gemzar (gemcitabine HCl), up 15 percent to $395.6 million; ... FDA news - FDA news (subscription)

United States Code of Federal Regulations - 42 CFR § 414.707 Basis of...  -  Jul 12, 2006
GOSERELIN ACETATE 80 RITUXIMAB 81 PACLITAXEL 81 DOCETAXEL 80 CARBOPLATIN 81 IRINOTECAN 80 GEMCITABINE HCL 80 PAMIDRONATE DISODIUM 85 DOLASETRON MESYLATE ... Pay-Per-View - United States Code of Federal Regulation... - Loislaw

EC clears Roche's Tarceva in pancreatic cancer.  -  Feb 5, 2007
...for the treatment of patients with metastatic pancreatic cancer, in combination with a standard chemotherapy, Eli Lilly's Gemzar (gemcitabine HCl). ... $4.95 - Pharma Marketletter - ECNext

Shilpa Medicare acquires Austrian company  -  Mar 31, 2008
Approvals from South Korea FDA officials for Gemcitabine HCL and Ambroxol HCL have opened up the South Korean markets for its products. ... Myiris.com

Lilly reiterates 2006/07 guidance, disappoints.(Eli Lilly and Co.)  -  Dec 18, 2006
Cymbalta is well-positioned after recent formulary wins, and Alimta and Gemzar [gemcitabine HCl] are reimbursed by all Medicare carriers," he added. Free with registration - Pharma Marketletter - AccessMyLibrary.com

Lilly's 1st-qtr 2007 earnings drop 39%.(Eli Lilly and Co.)(Financial...  -  Apr 23, 2007
Lilly's oncology agent Gemzar (gemcitabine HCl) contributed $376.9 million, up 11%, and sales of Alimta (permetrexed) jumped 44% to $187.8 million. ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Is it Lilly? ImClone Stays Mum on Mystery Big Pharma Bidder  -  Oct 3, 2008
...set to go off patent in 2011, and cancer drug Gemzar (gemcitabine HCl), which totaled $1.6 billion in 2007 and starts losing patent protection in 2010. ... BioWorld Online - BioWorld Online

FDA Reviewers Express Doubts Over Lilly's Proposed Ovarian Cancer …  -  Mar 13, 2006
The FDA's Oncologic Drugs Advisory Committee will discuss Lilly's proposed indication for Gemzar (gemcitabine HCl) injection plus carboplatin at its meeting ... Pay-Per-View - Drug Industry Daily - Factiva, from Dow Jones

Eli lilly sees 3rd qtr net income climb 6% as sales jump 19% to...  -  Oct 29, 2007
...which contributed $513.2 million, up 47%; the anticancer drugs Gemzar (gemcitabine HCl) and Alimta (pemetrexed for injection), sales of which grew 11% ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

FDA Grants Eli Lilly and Company's ALIMTA(R) Third US Approval  -  Sep 29, 2008
...randomized study (1725 patients) that evaluated ALIMTA plus cisplatin (AC arm) versus GEMZAR® (gemcitabine HCl for injection) plus cisplatin (GC arm). ... FierceBiotech

Lilly Says Study Shows Drug Helps Patients With Certain Cancers  -  May 28, 2008
...evaluated ALIMTA® (pemetrexed for injection) plus cisplatin versus GEMZAR® (gemcitabine HCl for injection) plus cisplatin, a standard of treatment in ... insideindianabusiness.com

SMS Pharma to invest Rs 1130.20 mn for expansion  -  Feb 8, 2007
Sildenafil Citrate, Omeprazole Magnesium, Ramipril, Almotriptan maleate, Gemcitabine HCl, Imatinib Mesilate and their intermediates. ... Myiris.com

Gemcitabine Based Regimens Improve Quality of Life in Non-Small Cell ...  -  May 18, 2005
By Eli Lilly, [RxPG] Data presented today(1,2,3) from ongoing clinical trials show that therapies based on Eli Lilly and Company's (LLY) Gemzar(R) ... RxPG NEWS

FDA Approves Lilly's Gemzar(R) For Ovarian Cancer Treatment  -  Jul 18, 2006
Today, Eli Lilly and Company (NYSE: LLY) announced that the United States Food and Drug Administration (FDA) has approved GEMZAR(R) (gemcitabine HCl) for ... Medical News Today - Medical News Today (press release)

Lilly Oncology To Unveil More Than 50 Studies At Asco 2008  -  May 7, 2008
The company will present the latest research findings on ALIMTA® (pemetrexed for injection), GEMZAR® (gemcitabine HCl for injection), and enzastaurin, ... Medical News Today - Medical News Today (press release)

Eli Lilly Japan's 2006 sales up 7% to $700M.(Financial report)(Brief...  -  Apr 2, 2007
...turnover of insulin products gained 5% to 14.1 billion yen; while income from the cancer drug Zemzar (gemcitabine HCl) jumped 18% to 12.9 billion yen. ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Enzon Reports Second Quarter 2006 Results; Company Continues to …  -  Jan 7, 2005
...the start of a phase I trial with Oncaspar(R) in combination with Gemzar(R) (gemcitabine HCl for Injection) in patients with advanced solid tumors and ... businesswire.com

Pemetrexed Approved in Europe for Histologically-Based First-Line …  -  Apr 11, 2008
...of NSCLC is based on a phase 3 randomised study that evaluated pemetrexed plus cisplatin versus injection gemcitabine HCl (Gemzar) plus cisplatin. ... DG News

FDA Approves Lilly's Gemzar(R) For Ovarian Cancer Treatment.  -  Jul 17, 2006
Food and Drug Administration (FDA) has approved GEMZAR(R) (gemcitabine HCl) for use in the treatment of women living with recurrent ovarian cancer. ... Free with registration - PR Newswire - AccessMyLibrary.com

Enzon Pharmaceuticals Announces Advancements in Its Oncology …  -  Jan 7, 2005
...its safety and potential utility in the treatment of advanced solid tumors and lymphomas in combination with Gemzar(R) (gemcitabine HCl for Injection). ... businesswire.com

Tarceva Linked to 2 Fatal Cases of Hepatotoxicity  -  Sep 23, 2008
...metastatic non–small cell lung cancer after failure of at least 1 prior chemotherapy regimen and in combination with gemcitabine HCl (Gemzar injection, ... Medscape

Lilly's income down 81%, but shares up 1.5%.  -  Feb 12, 2007
...including: the 4% increase to $781.7 million of its diabetes care range; its oncology agent Gemzar (gemcitabine HCl), which contributed $371.3 million, ... $4.95 - Pharma Marketletter - ECNext

Pharmion Corporation Initiates Phase One/Two Combination Clinical...  -  Oct 25, 2006
MGCD0103, in combination with Gemzar(R) (gemcitabine HCl; Eli Lilly and Co.) in patients with solid tumors, including pancreatic cancer. ... Free with registration - PR Newswire - AccessMyLibrary.com

Sun Gets FDA Tentative OK for Generic Gemzar  -  Mar 14, 2008
Sun's generic Gemzar (gemcitabine HCl) injections are available in 200-mg and 1-g vials. Combined, these strengths have annual sales of approximately $680 ... FDA news - FDA news (subscription)

Studies try to shed light on impact of race  -  Jun 3, 2007
...(gemcitabine HCl for injection) in treating non-small cell lung cancer (NSCLC) in African-Americans, Hispanics and other diverse populations. ... News-Medical.net

Lilly Breast Cancer Studies Explore Potential Role Of Pharmacogenomics...  -  Jun 4, 2006
...unveiled two breast cancer studies involving pharmacogenomics and its chemotherapies GEMZAR(R) (gemcitabine HCl) and ALIMTA(R) (pemetrexed). ... Medical News Today - Medical News Today (press release)

European Medicines Agency (EMEA) Approves ALIMTA® (pemetrexed …  -  Apr 14, 2008
...of NSCLC is rooted on a Phase III randomized trial that compared pemetrexed plus cisplatin with GEMZAR® (gemcitabine HCl for injection) plus cisplatin. ... Medical News Today - Medical News Today (press release)

New Data Show Enzastaurin's Activity Across Multiple Cancer Cell Lines  -  Jun 4, 2006
Clinical results also highlighted enzastaurin's potential to enhance the benefit of standard-of-care chemotherapies such as GEMZAR(R) (gemcitabine HCl), ... RedOrbit

Study supports activity of GEMZAR in the treatment of early-stage...  -  Jun 2, 2007
CHICAGO, June 2, 2007 -- GEMZAR® (gemcitabine HCl for injection), approved in combination with paclitaxel (Taxol®) in the first-line, post-surgical ... eurekalert.org

Press Release: Lilly Targeted Agent Shows Promise in Treating Primary...  -  May 17, 2005
...of innovation for the group, which has produced Gemzar(R) (gemcitabine HCl) and Alimta(R) (pemetrexed), two of the world's leading chemotherapy agents. ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Study Showed Alimta(R) (Pemetrexed For Injection) Improved Survival...  -  May 30, 2008
...evaluated ALIMTA® (pemetrexed for injection) plus cisplatin versus GEMZAR® (gemcitabine HCl for injection) plus cisplatin, a standard of treatment in ... Medical News Today - Medical News Today (press release)

Eli Lilly and Company  -  Sep 3, 2006
Alimta(R) (pemetrexed, Eli Lilly and Company) Gemzar(R) (gemcitabine HCl, Eli Lilly and Company) CeeNU(R) (lomustine [CCNU], Bristol Myers Squibb) (Logo: ... presseportal.ch

1,000-Patient Lung Cancer Diversity Study Launched By Lilly  -  Jun 6, 2007
GEMZAR® (gemcitabine HCl for injection) in treating non-small cell lung cancer (NSCLC) in African-Americans, Hispanics and other diverse populations. ... Medical News Today - Medical News Today (press release)

Positive CHMP Opinion For Histologically-Based Use Of ALIMTA(R) ( …  -  Feb 26, 2008
The CHMP recommendation in first-line NSCLC is based on a Phase III, randomized study that evaluated pemetrexed plus cisplatin versus gemcitabine HCl for ... Medical News Today - Medical News Today (press release)

Enzon Reports Second Quarter 2006 Results; Company Continues to …  -  Aug 1, 2006
...the start of a phase I trial with Oncaspar(R) in combination with Gemzar(R) (gemcitabine HCl for Injection) in patients with advanced solid tumors and ... Genetic Engineering News - Genetic Engineering News (press release)

Lilly files Alimta with EMEA for NSCLC.  -  Oct 1, 2007
Alimta-cisplatin combination was non-inferior to cistplatin plus Gemzar (gemcitabine HCl), also a Lilly product, in terms of overall patient survival. ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Lilly to Provide Details From More Than 50 Research Studies  -  May 1, 2008
The company will present the latest research findings on ALIMTA® (pemetrexed for injection), GEMZAR® (gemcitabine HCl for injection), and enzastaurin, ... insideindianabusiness.com

Enzon Pharmaceuticals Announces Advancements in Its Oncology …  -  Aug 1, 2006
...its safety and potential utility in the treatment of advanced solid tumors and lymphomas in combination with Gemzar(R) (gemcitabine HCl for Injection). ... Free with registration - Business Wire - AccessMyLibrary.com

Lilly Oncology Focused on Pharmacogenomics at AACR Annual Meeting  -  Apr 15, 2007
Many of the studies -- which investigate ALIMTA(R) (pemetrexed for injection); GEMZAR(R) (gemcitabine HCl for injection), enzastaurin and other products in ... Genetic Engineering News - Genetic Engineering News (press release)

Promising metastasis data for SR's Atu027 RNAi.(product development)(...  -  Dec 22, 2006
In particular, Atu027 RNAi was significantly more effective in the prevention of metastases than Eli Lilly's Gemzar (gemcitabine HCl), SR noted, ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

MethylGene Announces Third Quarter 2006 Results  -  Nov 1, 2006
In October, we announced the initiation of a Phase I/II trial in combination with Gemzar(R) (gemcitabine HCl, Eli Lilly and Company) in pancreatic cancer ... Genetic Engineering News - Genetic Engineering News (press release)

Eli Lilly Drug Shows Activity Across Multiple Cancer Types  -  Jun 6, 2006
...chemotherapies such as Lilly's Gemzar (gemcitabine HCl) and Alimta (pemetrexed), and Roche's Xeloda (capecitabine), with manageable side effects. ... RedOrbit

Eli Lilly's 2008 EPS forecast beats expectations as firm prepares for...  -  Dec 17, 2007
Marketing exclusivity on the anticancer drug Gemzar (gemcitabine HCl) expires in 2010. The agent netted $394.4 million in third-quarter 2007, ... $9.94 - Pharma Marketletter - Alacra Store

Solid Tumors; Enzon Pharmaceuticals initiates Oncaspar Phase I solid ...  -  Aug 28, 2006
...its safety and potential utility in the treatment of advanced solid tumors and lymphomas in combination with Gemzar (gemcitabine HCl for Injection). ... Pay-Per-View - Biotech Business Week - Factiva, from Dow Jones

Press Release: Lilly Studies Try to Shed Light on Impact of Race on...  -  Jun 1, 2007
GEMZAR(R) (gemcitabine HCl for injection) in treating non-small cell lung cancer (NSCLC) in African-Americans, Hispanics and other diverse populations. ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: FDA Grants Lilly's ALIMTA(R) (Pemetrexed for Injection)...  -  Sep 29, 2008
...randomized study (1725 patients) that evaluated ALIMTA plus cisplatin (AC arm) versus GEMZAR(R) (gemcitabine HCl for injection) plus cisplatin (GC arm). ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: American Society of Clinical Oncologists (ASCO) Comes ...  -  Nov 14, 2007
3 Lilly molecules, ASCO 2006 is definitely big for us," said ... patient outcomes." Key Lilly Abstracts for ASCO 2006: -- GEMZAR(R) (gemcitabine HCl ... ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Lilly Breast Cancer Studies Explore Potential Role of ...  -  Jun 3, 2006
...unveiled two breast cancer studies involving pharmacogenomics and its chemotherapies GEMZAR(R) (gemcitabine HCl) and ALIMTA(R) (pemetrexed). ... Pay-Per-View - PR Newswire - HighBeam Research

Lilly Oncology Focused on Pharmacogenomics at AACR Annual Meeting.  -  Apr 15, 2007
Many of the studies -- which investigate ALIMTA(R) (pemetrexed for injection); GEMZAR(R) (gemcitabine HCl for injection), enzastaurin and other products in ... $4.95 - PR Newswire - ECNext

LILLY ONCOLOGY FOCUSED ON PHARMACOGENOMICS AT AACR …  -  Apr 16, 2007
Many of the studies -- which investigate ALIMTA(R) (pemetrexed for injection); GEMZAR(R) (gemcitabine HCl for injection), enzastaurin and other products in ... $4.95 - AsiaPulse News - ECNext

Gemzar.(NEW INDICATIONS)(Brief article)  -  Aug 21, 2006
A new indication has been granted to Indianapolis-based Eli Lilly & Co, (317) 277-6583, for Gemzar (gemcitabine HCl). The drug, approved earlier for ... $4.95 - Drug Topics - ECNext

Roche/Genentech's pertuzumab could return from brink despite Ph II …  -  Jan 15, 2007
...or fallopian tube cancer were enrolled and received treatment with pertuzumab plus Eli Lilly's Gemzar (gemcitabine HCl), or Gemzar alone. ... $9.94 - Pharma Marketletter - Alacra Store

Press Release: LILLY (ELI) & COMPANY - Gemzar in Treatment of Breast ...  -  Jun 4, 2007
2007 - GEMZARA[R] (gemcitabine HCl for injection), approved in combination with paclitaxel (TaxolA[R]) in the first-line, post-surgical treatment of ... ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

Press Release: New Data Show Enzastaurin's Activity Across Multiple …  -  Jun 4, 2006
Clinical results also highlighted enzastaurin's potential to enhance the benefit of standard-of-care chemotherapies such as GEMZAR(R) (gemcitabine HCl), ... Pay-Per-View - PR Newswire - HighBeam Research

Solid Tumors; Enzon Pharmaceuticals initiates Oncaspar Phase I solid ...  -  Aug 29, 2006
...its safety and potential utility in the treatment of advanced solid tumors and lymphomas in combination with Gemzar (gemcitabine HCl for Injection). ... Pay-Per-View - Cancer Weekly - Factiva, from Dow Jones

Press Release: LILLY (ELI) & COMPANY - Study Showed Alimta …  -  May 28, 2008
...evaluated ALIMTAA[R] (pemetrexed for injection) plus cisplatin versus GEMZARA[R] (gemcitabine HCl for injection) plus cisplatin, a standard of treatment ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

Lilly's Gemzar wins 4th US cancer indication.  -  Jul 24, 2006
US drug major Eli Lilly says that the Food and Drug Administration has approved Gemzar (gemcitabine HCl) for use in the treatment of women living with ... $4.95 - Pharma Marketletter - ECNext

Press Release: Making Science Personal: Lilly Oncology to Unveil 76 …  -  May 23, 2007
The company will present important data on GEMZAR(R) (gemcitabine HCl for injection), ALIMTA(R) (pemetrexed for injection), and enzastaurin, ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Press Release: Lilly Oncology Focused on Pharmacogenomics at AACR …  -  Apr 15, 2007
Many of the studies -- which investigate ALIMTA(R) (pemetrexed for injection); GEMZAR(R) (gemcitabine HCl for injection), enzastaurin and other products in ... Pay-Per-View - PR Newswire Europe - HighBeam Research

Tarceva.(Research Capsules)(Clinical report)  -  Jun 1, 2007
...s Gemzar (gemcitabine HCl) may improve survival significantly in patients with advanced pancreatic cancer. The randomized, double-blind trial included 569 ... $4.95 - Pharmaceutical Representative - ECNext

Press Release: Lilly Oncology to Unveil More Than 50 Studies at ASCO ...  -  May 1, 2008
The company will present the latest research findings on ALIMTA(R) (pemetrexed for injection), GEMZAR(R) (gemcitabine HCl for injection), and enzastaurin, ... Pay-Per-View - PR Newswire - HighBeam Research

Gemzar.  -  Aug 21, 2006
A new indication has been granted to Indianapolis-based Eli Lilly & Co, (317) 277-6583, for Gemzar (gemcitabine HCl). The drug, approved earlier for ... $9.94 - Drug Topics - Alacra Store

Lymphoma drug gets EU Orphan Status.  -  Oct 1, 2007
...oncology agent Vidaza (azacitidine for injectable suspension); as an addition to Eli Lilly's Gemzar (gemcitabine HCl) in the treatment of solid tumors; ... $4.95 - Pharma Marketletter - ECNext

USA pharma: Lilly gets third indication for Alimta  -  Oct 1, 2008
...which evaluated Alimta plus cisplatin versus Gemzar (gemcitabine HCl for injection) plus cisplatin. The median survival was 10.3 months in both groups. ... $34.00 - EIU Country Analysis - Alacra Store

Press Release: Pharmion Corporation Initiates Phase One/Two …  -  Oct 25, 2006
MGCD0103, in combination with Gemzar(R) (gemcitabine HCl; Eli Lilly and Co.) in patients with solid tumors, including pancreatic cancer. ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: LILLY (ELI) & COMPANY - Potential Versatility of...  -  Jun 4, 2007
P-LLY ALIMTAA[R] (pemetrexed for injection), Lilly GEMZARA[R] (gemcitabine HCl for injection), Lilly bevacizumab (AvastinA[R]), Genentech oxaliplatin ... Pay-Per-View - PR Newswire UK Disclose - HighBeam Research

A press release distributed by PR Newswire Europe  -  May 23, 2006
Si desea conocer la información completa sobre la descripción visite Gemzar.com Gemzar(R) (gemcitabine HCl), Lilly. Taxol(R) (paclitaxel), Bristol-Myers ... prnewswire.co.uk

Lilly soumet un dossier pour une approbation européenne d'ALIMTA(R) (...  -  Sep 22, 2007
La soumission de la EMEA se base sur une étude qui a comparé l'ALIMTA en association avec le cisplatine avec le GEMZAR(R) (le gemcitabine HCl pour ... Caducée.net

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Brand Names/Synonyms:
gemcitabine HCl is also known by the following brand names and/or synonymsCCRIS 8984; DDFC; Dfdc; GEO; Gemcin; Gemcitabina [Inn-Spanish]; Gemcitabine; Gemcitabine Hcl; Gemcitabine Hydrochloride; Gemcitabine [Usan:Ban:Inn]; Gemcitabinum [Inn-Latin]; Gemtro; Gemzar

Drug Category:
gemcitabine HCl is categorized under the following by the FDA: Radiation-Sensitizing Agents; Immunosuppressive Agents; Antivirals; Antimetabolites; Antineoplastic Agents; ATC:L01BC05

Dosage Forms:
lyophilized powder for injection

Absorption:
100%

Interactions:
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Chemical IUPAC Name:
4-amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-pyrimidin-2-one





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