methylphenidate hydrochloride

This page contains recent news articles, when available, and an overview of methylphenidate hydrochloride but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

methylphenidate hydrochloride
(when available)

Pharmacology and use:
Methylphenidate, a central nervous system stimulant chemically similar to the amphetamines, is used to treat narcolepsy, attention-deficit hyperactivity disorder (ADHD) in children, post-stroke depression or other depressive disorders. Children with attention deficit disorders

Mechanism Of Action:
Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system. Alteration of serotonergic pathways via changes in dopamine transport may result.

News Articles on Methylphenidate

Methylphenidate Hydrochloride Increases Energy Expenditure in Healthy...  -  Jan 11, 2007
To examine the effects of methylphenidate hydrochloride (MPH) on resting energy expenditure (REE) and postprandial energy expenditure (PEE) and substrate ... Nature.com

… - 77 Ill. Adm. Code 790.6280 METHYLPHENIDATE HYDROCHLORIDE ( …  -  Aug 10, 2005
77 Ill. Adm. Code 790.6280 METHYLPHENIDATE HYDROCHLORIDE (Repealed) Repealed. (Source: Repealed at 16 Ill. Reg. 12913, effective August 10, 1992) ... Pay-Per-View - Illinois Administrative Code - Loislaw

attention-deficit hyperactivi ...  -  Jun 21, 2005
THIS STUDY analyzed records of 11537 youths, ages 6 to 17, who were prescribed various brands and formulations of methylphenidate hydrochloride (MPH), ... Pay-Per-View - Washington Post - ProQuest Archiver

Press Release: Actavis Launches Alprazolam ER Tablets in the US - PR ...  -  Feb 14, 2007
Administration (FDA) approval of Metadate(TM) ER Tablets (methylphenidate hydrochloride extended ... evaluation of the patient. Metadate(TM) ER Tablets ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Actavis Launches Glipizide ER Tablets in the US - PR …  -  Nov 6, 2006
Administration (FDA) approval of Metadate(TM) ER Tablets (methylphenidate hydrochloride extended ... evaluation of the patient. Metadate(TM) ER Tablets ... Pay-Per-View - PR Newswire - HighBeam Research

Medication for mischief?  -  Oct 14, 2005
The number of prescriptions for methylphenidate hydrochloride, ... According to the New Scientist, methylphenidate hydrochloride and speed have different ... Times Educational Supplement

Press Release: Mylan Announces Another First to Market With the...  -  Mar 26, 2007
Administration (FDA) approval of Metadate(TM) ER Tablets (methylphenidate hydrochloride extended ... evaluation of the patient. Metadate(TM) ER Tablets ... Pay-Per-View - PR Newswire - HighBeam Research

Article: USF player Robinson makes an impact as a freshman - Universit...  -  Oct 6, 2005
Metadate(TM) ER Tablets (CII) (methylphenidate hydrochloride ... ... Methylin ER (methylphenidate hydrochloride extended ... proven efficacy and safety. ... Pay-Per-View - University Wire - HighBeam Research

Barr Confirms Patent Challenge of Ritalin(R) LA.  -  Nov 2, 2007
Ritalin LA (methylphenidate hydrochloride) extended-release capsules are indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). ... Free with registration - PR Newswire - AccessMyLibrary.com

Concerta shows promise as ADHD drug.(attention-deficit hyperactivity ...  -  Feb 13, 2006
According to a recent study, long-acting formulations of Belgian firm Jansenn-Cilag's Concerta XL (methylphenidate hydrochloride) are more effective than ... $4.95 - Pharma Marketletter - ECNext

Michael Herbert Bird acquires a minority stake in BLIS Technologies...  -  Dec 13, 2007
Methylphenidate hydrochloride is a mild…Ritalin LA uses SO DAS technology, a proprietary drug delivery technology of Elan. The medication is…dose. ... Pay-Per-View - deals - Alacra Store

Mind control in Ritalin Nation  -  May 7, 2008
In some classrooms in the United States, five percent of the six-year-olds are on Ritalin (methylphenidate hydrochloride). ... Tehran Times

Long-awaited PBS listings announced  -  Apr 1, 2008
A slow release version of methylphenidate hydrochloride (Ritalin LA) has also been listed on the PBS for children aged between six and 18 years with ADHD. ... 6minutes

FDA looking at Adderall, other ADHD drugs, for heart risks - Feb. 2,...  -  Feb 2, 2006
The three drugs are based on separate compounds: methylphenidate hydrochloride for Ritalin; atomoxetine hydrochloride for Strattera, produced by Eli Lilly ... CNNMoney.com

Stressed Chinese parents "drug children" for exams  -  Jun 5, 2007
Their target is Ritalin, a drug used to treat Attention Deficit Hyperactivity Disorder (ADHD) containing the active ingredient methylphenidate hydrochloride ... Reuters India

Drugs for toddlers a joke  -  May 30, 2008
...most of these questions, your baby is suffering from a common case of ADHD and may be in need of the health benefits of Methylphenidate Hydrochloride. ... NEWS.com.au

Treatment for ADHD  -  Mar 27, 2006
Used properly, medicines such as methylphenidate hydrochloride (Ritalin) and other stimulants help suppress and regulate impulsive behavior. ... PsychCentral.com

Article: attention-deficit hyperactivi ... - The Washington Post |...  -  Jun 21, 2005
THIS STUDY analyzed records of 11537 youths, ages 6 to 17, who were prescribed various brands and formulations of methylphenidate hydrochloride (MPH), ... Pay-Per-View - Washington Post - HighBeam Research

Hyperactivity prescriptions triple in seven years  -  Nov 26, 2007
However, other drugs using the same ingredient - methylphenidate hydrochloride - soared over the same period. Prescriptions of Concerta rose from 43100 in ... Telegraph.co.uk

DJ HUGIN NEWS/Eurand Reports Recent Developments and Second …  -  Aug 7, 2008
...a 1999 development, license and supply agreement between the two companies for a sustained-release formulation of methylphenidate hydrochloride (MPH). ... financial.de

Article: The God pill; Psychedelic drugs.(Psychedelic drugs grow up)  -  Jul 15, 2006
For his control, Dr Griffiths decided to use methylphenidate hydrochloride, otherwise known as Ritalin, a drug that calms hyperactive children. ... Pay-Per-View - The Economist - HighBeam Research

Barr Confirms Patent Challenge of Ritalin LA  -  Nov 5, 2007
Barr filed its abbreviated new drug application containing a Paragraph IV certification for a generic Ritalin LA (methylphenidate hydrochloride) product ... FDA news - FDA news (subscription)

ADHD cases tied to lead, tobacco: Study: Even low levels of lead can ...  -  Sep 19, 2006
RITALIN Primary ingredient: Methylphenidate hydrochloride Other brands with ... Chicago Sun-Times. Article: Group to spread word on treatment of ADHD ... Pay-Per-View - Chicago Sun-Times - HighBeam Research

QUICK STUDY | Article from The Record (Bergen County, NJ) | HighBeam …  -  Jun 28, 2005
THIS STUDY analyzed records of 11537 youths, ages 6 to 17, who were prescribed various brands and formulations of methylphenidate hydrochloride (MPH), ... Pay-Per-View - The Record - HighBeam Research

New drug subsidies to benefit Coast patients | Sunshine Coast News | ...  -  Apr 2, 2008
ADHD sufferers between the ages of six and 18 can access a new slow release, single daily dose form of the drug Ritalin (methylphenidate hydrochloride). ... Sunshine Coast Daily - Sunshine Coast Daily

ADHD - Newly Published Canadian Study Demonstrates Long-Acting …  -  Feb 8, 2006
Canadian study published by The Canadian Journal of Clinical Pharmacology, long-acting, once-daily CONCERTA XL* (OROS* methylphenidate hydrochloride) is ... Medical News Today - Medical News Today (press release)

OnMedica - News: Dispensing figures show 23-fold variation across …  -  Jul 17, 2008
Pharmacists dispensed one prescription for methylphenidate hydrochloride – popularly known as Ritalin – for every seven children under 16 in 2007. ... OnMedica

Dopamine Influences ADHD | Psych Central News  -  Aug 7, 2007
...by the clinical effectiveness of stimulant drugs (methylphenidate hydrochloride and amphetamine), which increase extracellular dopamine in the brain.� ... PsychCentral.com

Methylphenidate may reduce hyperactivity in autistic kids.(care and …  -  May 1, 2006
In the first study, 11 preschool children with autism received gradually titrated doses in an open-label fashion with methylphenidate hydrochloride 1.25-10 ... Free with registration - Clinical Psychiatry News - AccessMyLibrary.com

Capture ends 2-week chase - Ozaukee ID case is part of long trail  -  Jan 15, 2007
28 with 27 misdemeanor counts of illegally prescribing more than 3000 tablets of Methylin and methylphenidate hydrochloride, which are closely related to ... $2.95 - Milwaukee Journal Sentinel - NewsBank

Eurand to Receive Million Payment and Litigation Settlement - Health ...  -  Aug 6, 2008
...license and supply agreement between the two companies for a sustained-release formulation of methylphenidate hydrochloride (MPH) co-developed by Eurand ... RedOrbit

Use of polysomnography with synchronized digital video recording to …  -  Jul 5, 2005
He was taking venlafaxine, 112 mg/d, and methylphenidate hydrochloride, 54 mg/d, prescribed 3 years earlier for attention-deficit hyperactivity disorder ... CMAJ

Thiensville psychiatrist in court after manhunt - He and girlfriend...  -  Oct 27, 2007
...also was charged in Wyoming with 27 misdemeanor counts of illegally prescribing more than 3000 tablets of Methylin and methylphenidate hydrochloride, ... $2.95 - Milwaukee Journal Sentinel - NewsBank

Ritalin and Russian Roulette  -  Feb 14, 2005
Its generic name is methylphenidate hydrochloride. It comes in two forms, a regular tablet, and a time-release tablet. It was described as follows: ... enterstageright.com

NewsChannel 5.com - Nashville, Tennessee - Sleep Disorder Awareness …  -  Mar 24, 2008
Stimulants include dextroamphetamine sulfate (Dexedrine, Dextrostat), methylphenidate hydrochloride (Ritalin, Concerta, others), and Cylert. ... NewsChannel5.com

News in brief - Feb. 27, 2006  -  Feb 27, 2006
2 that stimulant drugs, including Ritalin (methylphenidate hydrochloride), which are commonly prescribed for attention-deficit/hyperactivity disorder, ... American Medical News

Thiensville psychiatrist in court after manhunt; He and girlfriend...  -  Oct 27, 2007
...also was charged in Wyoming with 27 misdemeanor counts of illegally prescribing more than 3000 tablets of Methylin and methylphenidate hydrochloride, ... Pay-Per-View - Milwaukee Journal Sentinel - HighBeam Research

Suits, Protests Fuel a Campaign Against Psychiatry  -  Dec 18, 2005
Known generically as methylphenidate hydrochloride, Ritalin is intended for youngsters afflicted with "attention deficit disorder," more commonly known as ... SouthFlorida.com

Capture ends 2-week chase; Ozaukee ID case is part of long trail |...  -  Jan 15, 2007
28 with 27 misdemeanor counts of illegally prescribing more than 3000 tablets of Methylin and methylphenidate hydrochloride, which are closely related to ... Pay-Per-View - Milwaukee Journal Sentinel - HighBeam Research

Health & Medical News - Magic mushrooms hit the God spot - 12/07/2006  -  Dec 7, 2006
...scientifically rigorous study of its kind in 40 years, 36 volunteers were given either psilocybin or a comparator drug methylphenidate hydrochloride. ... ABC Regional Online - ABC Regional Online

Psychiatry Manufacturing Mental Illness and Subverting Society  -  Nov 14, 2005
...disorder" ADHD and is prescribed Ritalin ( or other Methylphenidate Hydrochloride derivatives ) which has the same effect on the brain as Cocaine. ... i-newswire.com

Article: Alpharma rolls out Flector pain Patch.(RX: RETAIL PHARMACY: ...  -  Mar 17, 2008
...has received final approval from the United States Food and Drug Administration ... ER) tablets, 20 mg. Alpharma's methylphenidate hydrochloride ... ... Pay-Per-View - Chain Drug Review - HighBeam Research

'I want to let children have a voice to understand the impact of...  -  Oct 6, 2006
ADHD is estimated to affect 6-15 per cent of children in the US compared with 1-3 per cent in the UK, with the drug methylphenidate hydrochloride (Ritalin) ... Times Higher Education

The active ingredient in magic mushrooms produces spiritual experience...  -  Feb 8, 2005
...scientifically rigorous study of its kind in 40 years, 36 volunteers were given either psilocybin or a comparator drug methylphenidate hydrochloride. ... ABC Regional Online - ABC Regional Online

New Hampshire Session Laws - Chapter 222 — 2008  -  Jun 16, 2008
...and, provided that with regard to amphetamines and methylphenidate hydrochloride, a prescription may be filled for up to a 60-day supply if either such ... Pay-Per-View - New Hampshire Session Laws - Loislaw

Daniel Vasella (CEO)  -  Dec 31, 2006
...letrozole (Femara), methylphenidate hydrochloride (Ritalin), terbinafine (Lamisil), etc. Novartis owns Sandoz, a large manufacturer of generic drugs. ... chemie.de

ADHD Appears to Be Associated With Depressed Dopamine Activity in …  -  Aug 9, 2007
...by the clinical effectiveness of stimulant drugs (methylphenidate hydrochloride and amphetamine), which increase extracellular dopamine in the brain." ... allamericanpatriots.com

Exposures to environmental toxicants and attention deficit hyperactivi...  -  Dec 1, 2006
...dextroamphetamine sulfate, methylphenidate hydrochloride, and unspecified ADHD medication, respectively. Children who had only stimulant medication use ... Free with registration - Environmental Health Perspectives - AccessMyLibrary.com

EBSCOhost Connection: HIGHEST EVER NUMBER OF UK KIDS ON …  -  Nov 1, 2005
Subject Terms:, METHYLPHENIDATE hydrochloride CHILD psychiatry CHILD mental health DRUGS -- Prescribing. Geographic Terms:, GREAT Britain ... Subscription - Ecologist - EBSCO Publishing

Painkillers taken in drug store burglary  -  Aug 23, 2006
...open a locked drawer and stole various bottles of pills, including OxyContin, oxycodone, hydrocodone and methylphenidate hydrochloride (Fentanyl). ... $2.95 - Erie Times-News - NewsBank

Shire and Novartis dip on ADHD drug risks  -  Mar 21, 2005
...system stimulants such as Ritalin (methylphenidate hydrochloride), which has a proven safety record with usage spanning more than 50 years to date. ... Pay-Per-View - Datamonitor News and Comment - Factiva, from Dow Jones

Barr confirms patent challenge to Novartis Ritalin.  -  Nov 12, 2007
...by Novartis Pharmaceuticals in connection with its Ritalin LA (methylphenidate hydrochloride) extended-release capsules, 10mg, 20mg, 30mg and 40mg. ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

ADHD Appears to Be Associated With Depressed Dopamine Activity in …  -  Aug 2, 2007
...by the clinical effectiveness of stimulant drugs (methylphenidate hydrochloride and amphetamine), which increase extracellular dopamine in the brain." ... newswise.com

The Gillette News-Record: News  -  Jan 10, 2007
The prescriptions were for methylin and methylphenidate hydrochloride, which are generics for the attention deficit disorder drug Ritalin. ... Gillette News Record

Less frequent dosing may aid ADHD kids  -  Aug 28, 2005
The latest: This study analyzed records of 11537 youths, ages 6 to 17, who were prescribed various brands and formulations of methylphenidate hydrochloride ... $2.95 - The Telegraph - NewsBank

Article: Methylphenidate may reduce hyperactivity in autistic...  -  May 1, 2006
In the first study, 11 preschool children with autism received gradually titrated doses in an open-label fashion with methylphenidate hydrochloride 1.25-10 ... Pay-Per-View - Clinical Psychiatry News - HighBeam Research

UCB launches Equasm for ADHD in children.(Brief Article)  -  Mar 28, 2005
Belgian drugmaker UCB Pharma has launched Equasm (methylphenidate hydrochloride), providing a new treatment option for attention-deficit hyperactivity ... Pay-Per-View - Pharma Marketletter - Factiva, from Dow Jones

SCOTS GPS HAND OUT 'SUICIDE' PILLS TO CHILDREN  -  Apr 2, 2006
Researchers in New York found that while Ritalin - which has the chemical name Methylphenidate Hydrochloride - is effective in calming hyperactive children ... Pay-Per-View - Express on Sunday - Factiva, from Dow Jones

Article: UCB launches a-peeling ads. - Financial Adviser | HighBeam …  -  Mar 30, 2006
Belgian drugmaker UCB Pharma has launched Equasm (methylphenidate hydrochloride), providing a new treatment option for attention-deficit hyperactivity ... Pay-Per-View - Financial Adviser - HighBeam Research

EBSCOhost Connection: Studying Shrooms.  -  Oct 1, 2006
METHYLPHENIDATE hydrochloride ENDOWMENT of research NATIONAL Institute on Drug Abuse. Geographic Terms:, UNITED States ... Subscription - Reason - EBSCO Publishing

New Hampshire Statutes - 318-B:9 Sale by Pharmacists.  -  May 5, 2006
...and, provided that with regard to amphetamines and methylphenidate hydrochloride, a prescription may be filled for up to a 60-day supply if either such ... Pay-Per-View - New Hampshire Statutes - Loislaw

Press Release: Barr Confirms Patent Challenge of Ritalin(R) LA. - PR ...  -  Nov 2, 2007
Pharmaceuticals Corporation in connection with its Ritalin(R) LA (methylphenidate hydrochloride) extended-release capsules, 10mg, 20mg, 30mg and 40mg. ... Pay-Per-View - PR Newswire - HighBeam Research

Ritalin figure 'greater than we believe to be true'  -  Jan 5, 2006
...specifically those which go under the generic heading of Methylphenidate Hydrochloride (eg Ritalin, Concerta, Equasym, and Methylphenidate itself). ... Pay-Per-View - Scunthorpe Evening Telegraph - Factiva, from Dow Jones

[U] In re Able Laboratories Securities Litigation, No. 05-2681 (DNJ...  -  Mar 24, 2008
Supreme Court Cases - Research for US Supreme Court Cases, Federal Circuit Court Cases, and Federal District Court Cases. Whether you need decisions in ... $2.95 - U.S. District Court, District of New... - VersusLaw

Steven Ray Flora (2007).(Taking America Off Drugs: Why Behavioral …  -  Sep 22, 2008
Article: Methylphenidate hydrochloride (ritalin) reduces operant ... The Psychological Record; March 22, 1993 ; 700+ words ... ... Franz, 1985). ... Pay-Per-View - Psychological Record - HighBeam Research

轉貼--新研究檢驗ADHD藥物所帶來的潛在心血管風險  -  Sep 19, 2007
...的趨勢;AHRQ最近一項��藥物使用的分�指出,3種ADHD藥物,分別是Concerta(methylphenidate hydrochloride(ALZA/McNeil Pediatrics))�Strattera(atomoxetine ... udn.com

Article: Schedule-induced and operant mechanisms that influence …  -  Jun 22, 2007
Article: Methylphenidate hydrochloride (ritalin) reduces operant ... The Psychological Record; March 22, 1993 ; 700+ words ... ... in the spatial and ... Pay-Per-View - Psychological Record - HighBeam Research

Brand Names/Synonyms:
methylphenidate hydrochloride is also known by the following brand names and/or synonyms4311/B Ciba; C 4311; CHEMBANK1663; Calocain; Centedein; Centedrin; Centedrine; Centredin; Concerta; Dea No. 1724; Focalin; Focalin Xr; HSDB 3126; METHYLPHEN; Meridil; Metadate; Metadate Cd; Metadate Er; Methyl Phenidyl Acetate; Methylin; Methylin Er; Methylofenidan; Methylphenidan; Methylphenidate; Methylphenidate Hcl; Methylphenidate Hydrochloride; Methylphenidatum [Inn-Latin]; Methylphenidylacetate Hydrochloride; Methypatch; Metilfenidat Hydrochloride; Metilfenidato [Inn-Spanish]; Metilfenidato [Italian]; Phenidylate; Plimasine; Pms-Methylphenidate; Riphenidate; Ritalin; Ritalin Hydrochloride; Ritalin La; Ritalin Sr; Ritalin-Sr; Ritaline; Ritcher Works

Drug Category:
methylphenidate hydrochloride is categorized under the following by the FDA: Adrenergic Agents; Dopamine Agents; Central Nervous System Agents; Anorexigenic Agents; Stimulants; ATC:N06BA04

Dosage Forms:
Tablets, SR tablets

Absorption:
readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. bioavailability is low (approx. 30%)

Interactions:
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Chemical IUPAC Name:
methyl2-phenyl-2-(2-piperidyl)ethanoate





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