tamoxifen citrate

This page contains recent news articles, when available, and an overview of tamoxifen citrate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

tamoxifen citrate
(when available)

Pharmacology and use:
Tamoxifen belongs to a class of drugs called selective estrogen receptor modulators (SERMs), which have both estrogenic and antiestrogenic effects. Tamoxifen has the same nucleus as diethylstilbestrol but possesses an additional side chain (trans isomer) which accounts for its antiestrogenic activity. Tamoxifen, chemically related to clomiphene., is used to in the therapy of metastatic breast cancer. for the treatment of breast cancer

Mechanism Of Action:
Tamoxifen binds to estrogen receptors (ER), inducing a conformational change in the receptor. This results in a blockage or change in the expression of estrogen dependent genes. The prolonged binding of tamoxifen to the nuclear chromatin of these results in reduced DNA polymerase activity, impaired thymidine utilization, blockade of estradiol uptake, and decreased estrogen response. It is likely that tamoxifen interacts with other coactivators or corepressors in the tissue and binds with different estrogen receptors, ER-alpha or ER-beta, producing both estrogenic and antiestrogenic effects.

News Articles on Tamoxifen

Cytogen Corporation - SWOT Analysis - Aarkstore Enterprise  -  ‎Nov 10, 2009‎
The company currently markets Quadramet (samarium Sm-153 lexidronam injection), Prostascint (capromab pendetide), and Soltamox (tamoxifen citrate) to the US ... PRMinds (press release)

æŸ?些é ?防性藥物å?¯æ¸›å°‘乳癌風險但會增加其他風險  -  ‎Oct 23, 2009‎
...波特蘭奧勒岡å?¥åº·èˆ‡ç§‘學大學的Heidi D. Nelson醫師等人寫é?“,最近的臨床試驗顯示,é?¸æ“‡æ€§é›Œæ¿€ç´ å?—體調節劑tamoxifen citrate與raloxifene以å?Šé?¸æ“‡æ€§çµ„織雌激素活性調節 ... 臺灣新浪網

In re Tamoxifen Citrate Antitrust Litigation, 429 F.3d 370 (2d Cir....  -  Nov 2, 2005
Supreme Court Cases - Research for US Supreme Court Cases, Federal Circuit Court Cases, and Federal District Court Cases. Whether you need decisions in ... $2.95 - U.S. Court of Appeals, Second Circuit - VersusLaw

… of Appeals Denies Rehearing Request in Dismissal of Tamoxifen...  -  Sep 18, 2006
Barr launched its generic version of Tamoxifen Citrate in February 2003. Approximately 30 class action complaints were filed by consumers and/or third party ... Free with registration - PR Newswire - AccessMyLibrary.com

US Supreme Court Denies Review of Tamoxifen Citrate Antitrust...  -  Jun 25, 2007
WOODCLIFF LAKE, NJ, June 25 /PRNewswire-FirstCall/ -- Barr Pharmaceuticals, Inc. today announced that the United States Supreme Court has denied the ... Free with registration - PR Newswire - AccessMyLibrary.com

… Court Denies Review of Tamoxifen Citrate Antitrust Lawsuits. - PR ...  -  Jun 25, 2007
US Supreme Court Denies Review of Tamoxifen Citrate Antitrust Lawsuits. from PR Newswire. Highbeam Research – FREE Trial. Pay-Per-View - PR Newswire - HighBeam Research

… With Polycystic Ovary Syndrome: Tamoxifen Citrate an Effective A  -  Feb 16, 2005
Tamoxifen citrate (TMX), another non-steroidal selective estrogen ... Another selective estrogen receptor modulator (SERM), tamoxifen citrate (TMX), ... RedOrbit

Competitors by Product Report  -  May 10, 2008
Barr Pharmaceuticals, Inc. (BRL) Products:. Tamoxifen Citrate ... IVAX Tamoxifen Citrate; Tamoxifen Citrate. Musculoskeletal System. Metastatic ... $75.00 - Revere Reports - Revere

TAMOXIFEN (Oral route) - ta-MOX-i-fen.(Drug overview)  -  May 1, 2007
Uterine malignancies consist of both endometrial adenocarcinoma (incidence rate per 1000 women-years of 2.20 for tamoxifen citrate versus 0.71 for placebo) ... Free with registration - USP DI-Volume II, Advice for the... - AccessMyLibrary.com

… of Appeals Denies Rehearing Request in Dismissal of Tamoxifen...  -  Sep 18, 2006
Barr launched its generic version of Tamoxifen Citrate in February 2003. ... 20mg tablet complements Barr's 10mg Tamoxifen Citrate product. ... Pay-Per-View - PR Newswire - HighBeam Research

… of Appeals denies rehearing request in dismissal of Tamoxifen...  -  Sep 1, 2006
Barr launched its generic version of Tamoxifen Citrate in February 2003. ... The ... and AstraZeneca in the Tamoxifen Citrate antitrust litigation ... Pay-Per-View - BIOTECH Patent News - HighBeam Research

… of Appeals Reports - IN RE TAMOXIFEN CITRATE ANTITRUST LIT., 429 …  -  Nov 2, 2005
IN RE TAMOXIFEN CITRATE ANTITRUST LIT., 429 F.3d 370 (2nd Cir. ... See In re Tamoxifen Citrate Antitrust Litig., 277 F.Supp.2d 121 , 125-26 (E.D.N.Y. 2003) ... Pay-Per-View - United States 2nd Circuit Court of... - Loislaw

… Reports - IN RE TAMOXIFEN CITRATE ANTITRUST LITIGATION, 466 F. …  -  Aug 10, 2006
IN RE TAMOXIFEN CITRATE ANTITRUST LITIGATION, 466 F.3d 187 (2nd Cir. ... See In re Tamoxifen Citrate Antitrust Litig., 277 F.Supp.2d 121 , 125-26 (E.D.N.Y. ... Pay-Per-View - United States 2nd Circuit Court of... - Loislaw

65 -- TAMOXIFEN CITRATE TABLETS  -  Aug 12, 2005
CLASSIFICATION CODE: 65 - Medical, dental & veterinary equipment & supplies SUBJECT: 65 -- TAMOXIFEN CITRATE TABLETS SOLICITATION NUMBER: 797-NC-05-0038 ... Pay-Per-View - FedBizOpps - Factiva, from Dow Jones

[U] Greco v. CVS Corp., No. 04-5730, 164 Fed.Appx. 75 (2d Cir. 01/25/...  -  Jan 25, 2006
We are not certain that plaintiff's benefit plan provided any administrative remedies for her claim that tamoxifen citrate was misclassified as a brand-name ... $2.95 - U.S. Court of Appeals, Second Circuit - VersusLaw

Supreme Court Will Not Hear Tamoxifen Case  -  Jun 27, 2007
...“We have always believed that our patent challenge settlement related to tamoxifen citrate was pro-consumer and pro-competitive, and this has now been ... FDA news - FDA news (subscription)

… of Appeals denies rehearing request in dismissal of Tamoxifen...  -  Sep 1, 2006
Barr launched its generic version of Tamoxifen Citrate in February 2003. Approximately 30 class action complaints were filed by consumers and/or third party ... Free with registration - BIOTECH Patent News - AccessMyLibrary.com

ARIMIDEX(R) Gains Full FDA Approval for Adjuvant Treatment of …  -  Sep 21, 2005
NOLVADEX(R) (tamoxifen citrate) is approved for the adjuvant treatment of node-positive and node- negative early breast cancer in postmenopausal women ... Medical News Today - Medical News Today (press release)

Cytogen Launches SOLTAMOX(TM), First Oral Liquid Formulation of …  -  Aug 16, 2006
Each 5mL dose contains 15.2 mg tamoxifen citrate, which is equivalent to 10 mg tamoxifen. The recommended daily dose is 20-40 mg. Dosages greater than 20 mg ... Free with registration - PR Newswire - AccessMyLibrary.com

Reverse Payment Patent Settlements: the Interplay of Antitrust and...  -  Oct 3, 2008
FTC3 and In re Tamoxifen Citrate Antitrust Litigation4 were appealed to the Supreme Court of the United States, which denied certiorari in both cases. ... $9.94 - Mondaq Business Briefing - Alacra Store

Federal Register 2008 - 73 FR 79486 Teva Pharmaceutical Industries...  -  Dec 29, 2008
...(9) tamoxifen citrate tablets; and (10) tetracycline HCl capsules. ... (6) tamoxifen citrate tablets; (7) metronidazole tablets; (8) trazodone HCl ... Pay-Per-View - Federal Register 2008 - Loislaw

CYTOGEN LAUNCHES SOLTAMOX ORAL LIQUID FOR BREAST …  -  Oct 1, 2006
Each 5mL dose contains 15.2 mg tamoxifen citrate, which is equivalent to 10 mg tamoxifen. The recommended daily dose is 20-40 mg. Dosages greater than 20 mg ... Entrepreneur

FDA Approvals: Arranon, Kaletra Tablets, Soltamox  -  Nov 3, 2005
On Oct. 29, the FDA approved a new 10-mg/5-mL oral solution formulation of tamoxifen citrate (Soltamox, made by Savient Pharmaceuticals, Inc.) for the ... Medscape

US Supreme Court backs Barr in tamoxifen antitrust suit.  -  Jul 2, 2007
..."We have always believed that our patent challenge settlement related to tamoxifen citrate was pro-consumer and pro-competitive, and this has now been ... $9.94 - Pharma Marketletter - Alacra Store

US Court of Appeals Affirms Dismissal of Tamoxifen Antitrust Lawsuits.  -  Nov 3, 2005
Barr launched its generic version of Tamoxifen Citrate in February 2003. Approximately 30 class action complaints were filed by consumers and/or third party ... Free with registration - PR Newswire - AccessMyLibrary.com

FDA Safety Labeling Changes: Vistaril, Estraderm, Nolvadex  -  Mar 2, 2005
14, the FDA approved revisions to the safety labeling for tamoxifen citrate tablets (Nolvadex, made by AstraZeneca Pharmaceuticals, LP) to warn of the risk ... Medscape

Press Release: Cytogen and Savient Sign Letter of Intent for Marketing...  -  Feb 8, 2006
Soltamox (tamoxifen citrate) oral solution 10 mg/5 mL is indicated for metastatic breast cancer, adjuvant treatment of breast cancer, ductal carcinoma in ... Pay-Per-View - PR Newswire - HighBeam Research

Cure-all drug remains risky.(Breast Tumors)(Brief Article)  -  Feb 1, 2005
The drug tamoxifen citrate not only helps prevent recurrence of breast cancer, but can keep the deadly disease from appearing in the first place in some ... Free with registration - USA Today (Magazine) - AccessMyLibrary.com

Cytogen Launches First Oral Liquid Formulation of Hormonal Therapy...  -  Aug 17, 2006
Each 5mL dose contains 15.2 mg tamoxifen citrate, which is equivalent to 10 mg tamoxifen. The recommended daily dose is 20-40 mg. Dosages greater than 20 mg ... DG News

Press Release: US Court of Appeals Affirms Dismissal of Tamoxifen …  -  Nov 3, 2005
Barr launched its generic version of Tamoxifen Citrate in February 2003. Approximately 30 class action complaints were filed by consumers and/or third party ... Pay-Per-View - PR Newswire - HighBeam Research

EBSCOhost Connection: Cure-All Drug Remains Risky.  -  Feb 1, 2005
YOUR HEALTH BREAST TUMORS Cure-All Drug Remains Risky Cure-All Drug Remains Risky The drug tamoxifen citrate not only helps prevent recurrence of breast ... Subscription - USA Today Magazine - EBSCO Publishing

Cytogen and Savient Finalize Exclusive Distribution Agreement for …  -  Apr 24, 2006
...today the execution of a distribution agreement granting Cytogen exclusive marketing rights for SOLTAMOX(TM) (tamoxifen citrate) in the United States. ... $4.95 - PR Newswire - ECNext

Article: US is open to binding agreement on climate - International...  -  Feb 27, 2008
Business Wire; August 28, 1998 ; 700+ words ... ... tamoxifen citrate) in the United States. Details of a binding agreement are currently being finalized . ... Pay-Per-View - International Herald Tribune - HighBeam Research

[U] Debussy LLC v. Deutsche Bank AG, No. 06-3305-cv (2d Cir. 06/19/ …  -  Jun 19, 2007
In re Tamoxifen Citrate Antitrust Litig., 466 F.3d 187, 200 (2d Cir. 2006). We accept as true the facts alleged in the complaint and draw inferences from ... $2.95 - U.S. Court of Appeals, Second Circuit - VersusLaw

Port Washington Teachers' Association v. Board of Education of The...  -  Feb 27, 2007
In re Tamoxifen Citrate Antitrust Litig., 466 F.3d 187, 200 (2d Cir. 2006). We accept as true the facts alleged in the complaint and draw inferences from ... $2.95 - U.S. Court of Appeals, Second Circuit - VersusLaw

Wertz v. Washington Mutual Bank, No. 2:08-cv-317-GEB-KJM (EDCal. 04/ …  -  Apr 23, 2008
...(Opp'n at 12:1-10 (citing In re Tamoxifen Citrate Antitrust Litig., 222 F. Supp. 2d 326, 330 (EDNY 2002)).) "Artful pleading exists where a plaintiff ... $2.95 - U.S. District Court, Eastern District... - VersusLaw

Cytogen Receives Nasdaq Notification Related to Minimum Bid  -  Nov 5, 2007
The Company also currently has US commercial rights to SOLTAMOX(TM) (tamoxifen citrate), a liquid hormonal therapy approved in the US for the treatment of ... Bloomberg

Cytogen to Present at the BIO Investor Forum 2007  -  Oct 3, 2007
...(tamoxifen citrate) is the first liquid hormonal therapy approved in the US for the treatment of breast cancer in adjuvant and metastatic settings. ... Bloomberg

FTC chief concerned about drug patent deals  -  Jan 11, 2006
The patent settlement challenged in that case involved AstraZeneca's Tamoxifen Citrate, the most widely prescribed drug for breast cancer treatment. ... Reuters

Arimidex (anastrozole) featured in studies evaluating impact of...  -  Dec 9, 2005
Tamoxifen Nolvadex (tamoxifen citrate) is approved for the adjuvant treatment of node-positive and node-negative early breast cancer in postmenopausal women ... Pay-Per-View - Company Reports - Factiva, from Dow Jones

OTCPicks.com Daily Market Movers Digest Midday Report  -  Mar 11, 2008
It markets QUADRAMET (samarium Sm-153 lexidronam injection), PROSTASCINT (capromab pendetide), and SOLTAMOX (tamoxifen citrate) to the United States ... TransWorldNews - TransWorldNews (press release)

Supreme Court Hears Student Speech Case  -  Mar 19, 2007
The case is Tamoxifen Citrate Antitrust Litigation v. Barr Laboratories. The Solicitor General's office will submit its brief and then the Supreme Court ... Subscription - Wall Street Journal Online - Dow Jones & Company

Porat v. Lincoln Towers Community Association, 464 F.3d 274 (2d Cir....  -  Sep 18, 2006
See In re Tamoxifen Citrate Antitrust Litig., No. 03-7641, ___ F.3d ____, 2006 WL 2401244, at *28 (2d Cir. Aug. 10, 2006) ("It is within the court's ... $2.95 - U.S. Court of Appeals, Second Circuit - VersusLaw

Clinical Oncology Publishes Findings from First-Ever Initiative on …  -  Mar 11, 2008
AstraZeneca has provided the financial support for the five-year project and has donated (tamoxifen citrate) NOLVADEXÃ’ and (anastrozole). ARIMIDEXÃ’. ... webwire.com

Miller v. IBM World Trade Corp., No. 06 Civ. 4452 (SDNY 03/08/2007)  -  Mar 8, 2007
In re Tamoxifen Citrate Antitrust Litig., 466 F.3d 187, 200 (2d Cir. 2006) (citation omitted). It may "dismiss a complaint only if it is clear that no ... $2.95 - U.S. District Court, Southern District... - VersusLaw

2 hit with fed steroid rap. Bodybuilder, pharmacist nabbed  -  Apr 25, 2005
...sold nandrolone decanoate, an injectable anabolic steroid known to increase muscle mass, and tamoxifen citrate, a medicine commonly used to counteract ... New York Daily News

Ocala Star-Banner : Police beat for August 13, 2008<br>Gun owner …  -  Aug 13, 2008
Police said they found the pipe, eight Clonazepam, a gram of methamphetamine and 10 Tamoxifen Citrate in a plastic envelope. Koeck faces several charges, ... $2.95 - Ocala Star-Banner - NewsBank

[U] Sutton v. Wachovia Securities, LLC, 208 Fed.Appx. 27 (2d Cir....  -  Dec 7, 2006
Barr Labs., Inc. (In re Tamoxifen Citrate Antitrust Litig.), 429 F.3d 370, 404 (2d Cir. 2005). Even on appeal, the Suttons have failed to show how they ... $2.95 - U.S. Court of Appeals, Second Circuit - VersusLaw

Sanofi-Synthelabo v. Apotex Inc., 492 F.Supp.2d 353 (SDNY 06/19/2007)  -  Jun 19, 2007
See 21 U.S.C. § 355(j)(5)(B)(iv); see also In re Tamoxifen Citrate Antitrust Litig., 429 F.3d 370, 376 (2d Cir. 2005). [14], In response to that ANDA filing ... $2.95 - U.S. District Court, Southern District... - VersusLaw

WHO expert committee on specifications for pharmaceutical preparations...  -  Aug 1, 2005
...sulfamethoxypyridazine 100mg 178079 9930421 sulfanilamide 100mg 179094 9930424 sulfasalazine 100mg 191155 9930425 tamoxifen citrate 100mg 196208 9930427 ... Free with registration - Technical Report Series - AccessMyLibrary.com

Breast cancer drugs added to PBS  -  Oct 27, 2006
It will be available for patients who have already had a minimum of two years treatment with another breast cancer drug, tamoxifen citrate. ... NEWS.com.au

Petrohawk Energy Corp. v. Law Debenture Trust Co. of New York, No. 06...  -  Jan 29, 2007
In re Tamoxifen Citrate Antitrust Litig., 466 F.3d 187, 200 (2d Cir. 2006) (citation omitted). It may "dismiss a complaint only if it is clear that no ... $2.95 - U.S. District Court, Southern District... - VersusLaw

Select AIDS, cancer drugs to become cheaper  -  Mar 3, 2006
...etoposide, flutamide, ondansetron, pacitaxel, tamoxifen citrate, vinblastine sulphate, and vincristine, said an industry representative. ... Hindu Business Line

Original online series produced by HealthiNation will get girls...  -  Nov 1, 2008
The FDA has approved AstraZeneca's breast cancer drug Nolvadex (tamoxifen citrate) to reduce the risk of invasive breast cancer in women with ducral ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

CommonHealth.(AGENCIES)(appointment of Marc Weiner )(Brief article) |...  -  Oct 1, 2008
The FDA has approved AstraZeneca's breast cancer drug Nolvadex (tamoxifen citrate) to reduce the risk of invasive breast cancer in women with ducral ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Hbouss v. Coca-Cola Enterprises Inc., No. 05 Civ. 7965 (SDNY 08/09/ …  -  Aug 9, 2006
In re Tamoxifen Citrate Antitrust Litig., 429 F.3d 370, 384 (2d Cir. 2005) (citation omitted). The court's duty "is not to weigh the evidence that might be ... $2.95 - U.S. District Court, Southern District... - VersusLaw

Article: "You see that ball as cancer. You see that ball, and you...  -  Mar 20, 2006
BIOWORLD Today; November 2, 1998 ; 700+ words ... ... tamoxifen citrate) for the reduction of breast cancer in high-risk women. ... Pay-Per-View - The Record - HighBeam Research

Article: Hoping to cast out breast cancer - The Record (Bergen...  -  Jan 2, 2006
BIOWORLD Today; November 2, 1998 ; 700+ words ... ... tamoxifen citrate) for the reduction of breast cancer in high-risk women. ... Pay-Per-View - The Record - HighBeam Research

Article: Display shows the hidden side of breast cancer - The Record...  -  Apr 28, 2006
BIOWORLD Today; November 2, 1998 ; 700+ words ... ... tamoxifen citrate) for the reduction of breast cancer in high-risk women. ... Pay-Per-View - The Record - HighBeam Research

Lumbermens Mutual Casualty Co. v. Banco Espanol de Credito, SA, No. …  -  Oct 13, 2006
...[21], In re Tamoxifen Citrate Antitrust Litig., 429 F.3d 370, 404 (2d Cir. 2005).*fn4 Thus, when a plaintiff seeks to file a proposed amended complaint in ... $2.95 - U.S. District Court, Southern District... - VersusLaw

Loislaw Federal District Court Opinions - GUYON v. BASSO (EDVa. 2005)  -  Dec 8, 2005
2003) (same); In re Tamoxifen Citrate Antitrust Litig., 222 F. Supp. 2d 326, 335 (EDNY 2002) (same). Under the intermediate rule, sometimes referred to as ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Shares of Cytogen rise on 3Q earnings  -  Nov 5, 2007
...gain of $5.5 million and a non-cash impairment charge of $1.8 million associated with assets related to its tamoxifen citrate product, Soltamo. ... ABCmoney.co.uk

Aromatase Inhibitors Declared Superior to Tamoxifen in the Adjuvant …  -  Aug 1, 2006
Nolvadex(R) (tamoxifen citrate) is approved for the adjuvant treatment of node-positive and node-negative early breast cancer in postmenopausal women ... DG News

Antidote.(NEWS)(Brief article) | Article from Medical Marketing &...  -  Nov 1, 2008
The FDA has approved AstraZeneca's breast cancer drug Nolvadex (tamoxifen citrate) to reduce the risk of invasive breast cancer in women with ducral ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Aromatase Inhibitors Declared Superior To Tamoxifen In The Adjuvant …  -  Aug 3, 2006
NOLVADEXо (tamoxifen citrate) is approved for the adjuvant treatment of node-positive and node-negative early breast cancer in postmenopausal women ... Medical News Today - Medical News Today (press release)

Loislaw Federal District Court Opinions - GRECO v. CVS CORPORATION …  -  Jan 21, 2005
...which deprived plaintiff of the benefit of paying a "generic" co-payment for the drug tamoxifen citrate, marketed by Barr Laboratories. ... Pay-Per-View - Loislaw Federal District Court Opinions - Loislaw

Prescription of Tamoxifen for Breast Cancer Prevention by Primary...  -  Nov 13, 2006
Background Although tamoxifen citrate has been approved for primary reduction of breast cancer risk since 1998, little is known about the prescription of ... Archives of Internal Medicine

Bankruptcy Trust of Sillam v. Refco Group, LLC, No. 05 Civ. 10072...  -  Jul 28, 2006
In re Tamoxifen Citrate Antitrust Litig., 429 F.3d 370, 404 (2d Cir. 2005). However, while such a denial would be within the Court's discretion, ... $2.95 - U.S. District Court, Southern District... - VersusLaw

Rep. Anna Eshoo.(Update)(Brief article) | Article from Medical...  -  May 1, 2008
The FDA has approved AstraZeneca's breast cancer drug Nolvadex (tamoxifen citrate) to reduce the risk of invasive breast cancer in women with ducral ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

5 Years Of Treatment With Arimidex(R) Didn't Cause Osteoporosis In …  -  Jun 5, 2006
NOLVADEX(R) (tamoxifen citrate) is approved for the adjuvant treatment of node-positive and node-negative early breast cancer in postmenopausal women ... Medical News Today - Medical News Today (press release)

Cytogen Reports First Quarter 2007 Financial Results  -  Mar 31, 2007
Cytogen's first quarter 2007 results do not include revenues from CAPHOSOL ® and SOLTAMOX™ (tamoxifen citrate), which were introduced in March 2007 and ... businesswire.com

Tamoxifen is now available in liquid form.(PHARMACY CORNER)( …  -  Nov 1, 2006
Cytogen Corporation (Princeton, NJ) announced that Soltamox[TM] (tamoxifen citrate, oral solution 10 mg/5 ml), the first liquid form of the hormonal breast ... Free with registration - Oncology Nursing Forum - AccessMyLibrary.com

Teva Pharmaceuticals.(RX/GENERIC DRUGS--Profiles)(Teva …  -  Sep 29, 2008
Tamoxifen Citrate tablets, AB rated and bioequivalent to ... release tablets), AB rated and bioequivalent to ... Chain Drug Review ... Pay-Per-View - Chain Drug Review - HighBeam Research

Cytogen Selling PSMA Joint Venture Share To Progenics  -  Apr 25, 2006
The deal gives Cytogen exclusive US marketing rights for Soltamox (tamoxifen citrate), a cytostatic estrogen receptor antagonist, which is the first oral ... BioWorld Online - BioWorld Online

Cytogen Reports Second Quarter 2007 Financial Results  -  Aug 8, 2007
...respectively, for the same periods in 2006, primarily due to costs associated with the launches of CAPHOSOL and SOLTAMOX(TM) (tamoxifen citrate). ... Genetic Engineering News - Genetic Engineering News (press release)

Cytogen Announces Initiation of Phase 1 Trial for Radiolabeled...  -  Feb 27, 2007
PROSTASCINT(R) (capromab pendetide), and SOLTAMOX(TM) (tamoxifen citrate) to the US oncology market. QUADRAMET is approved for the treatment of pain in ... Genetic Engineering News - Genetic Engineering News (press release)

Cytogen Announces Initiation of Phase III Study Involving QUADRAMET( …  -  Jul 26, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... Free with registration - PR Newswire - AccessMyLibrary.com

Cytogen Enters into QUADRAMET(R) Royalty Buyout Agreement With …  -  May 8, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate) in the United ... RedOrbit

Cytogen Corporation to Present at the Rodman &amp; Renshaw 3rd …  -  May 9, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate) in the United ... Free with registration - PR Newswire - AccessMyLibrary.com

PSMA May Be An Appropriate Target For Both Imaging And Therapeutic …  -  May 23, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... Medical News Today - Medical News Today (press release)

Savient Pharmaceuticals Reports Second Quarter and First Half 2006 …  -  Aug 9, 2006
Finalized the US marketing rights for Soltamox(TM) (tamoxifen citrate) with Cytogen Corporation granting exclusive marketing rights for an upfront licensing ... businesswire.com

Cytogen to Raise $10.1 Million through Private Placement of Common …  -  Jun 29, 2007
...(tamoxifen citrate) is the first liquid hormonal therapy approved in the US for the treatment of breast cancer in adjuvant and metastatic settings. ... Genetic Engineering News - Genetic Engineering News (press release)

Cytogen Announces New Sales and Marketing Leadership with the …  -  Jun 11, 2007
...(tamoxifen citrate) is the first liquid hormonal therapy approved in the US for the treatment of breast cancer in adjuvant and metastatic settings. ... Genetic Engineering News - Genetic Engineering News (press release)

Cancer Patients Show Reduced Pain And Lower Analgesic Consumption …  -  Sep 20, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... Medical News Today - Medical News Today (press release)

Cytogen Corporation and Mayor Rudy Giuliani to Ring in Prostate...  -  Aug 28, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... Free with registration - PR Newswire - AccessMyLibrary.com

Breast pain (mastalgia)  -  Nov 3, 2007
Danazol, bromocriptine, and tamoxifen citrate are prescription medicines used for the treatment of severe cyclic breast pain. These medicines are rarely ... MSN Health & Fitness

Cytogen and Savient Sign Letter of Intent for Marketing of SOLTAMOX(TM...  -  Feb 8, 2006
...of intent to negotiate a definitive agreement granting Cytogen exclusive marketing rights for SOLTAMOX(TM) (tamoxifen citrate) in the United States. ... Free with registration - PR Newswire - AccessMyLibrary.com

Phosphagenics initiates anti-cancer compound animal trials  -  Jan 24, 2006
...on by this encouraging preliminary data, which also claimed a significant advantage over the anti-breast cancer drug Nolvadex (tamoxifen citrate). ... In-PharmaTechnologist.com

Cytogen Reports Third Quarter 2006 Financial Results.  -  Nov 2, 2006
In August 2006, Cytogen began introducing SOLTAMOX (tamoxifen citrate) to the US oncology market. During the third quarter 2006, Cytogen began supplying the ... Free with registration - PR Newswire - AccessMyLibrary.com

CVV, CYTO, INPC, PKTR, PONE, HAPN Have Been Added To Naked …  -  Oct 5, 2007
It markets QUADRAMET (samarium Sm-153 lexidronam injection), PROSTASCINT (capromab pendetide), and SOLTAMOX (tamoxifen citrate) to the United States ... Free with registration - M2 Presswire - AccessMyLibrary.com

Current Research on the Use of Hormonal Therapy in the Treatment of …  -  Feb 17, 2005
Tamoxifen citrate (TAM), an anti-estrogen that has proven valuable in breast cancer treatment, has been investigated as an adjunct to progestin therapy due ... RedOrbit

Cytogen Announces Initiation Of Phase III Study Involving QUADRAMET( …  -  Jul 27, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... Medical News Today - Medical News Today (press release)

Iran develops polymer to fight cancer  -  Oct 14, 2007
The new system made from polycaprolactone-folate can be used as a carrier for tamoxifen citrate, a commonly used chemotherapy drug in breast cancer patients ... PRESS TV

Cytogen to Release Second-Quarter 2006 Earnings and Host Conference …  -  Aug 7, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... prnewswire.com

Cytogen's 4th-qtr 2006 losses up 85.4%.(earnings of CYTOGEN Corp.)( …  -  Mar 12, 2007
It attributed the deepening losses to costs associated with its anticancer drug Soltamox (tamoxifen citrate), which was introduced in the USA last spring, ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Cytogen Retains ThinkEquity Partners to Assist in the Evaluation of …  -  May 11, 2007
...(tamoxifen citrate), a liquid hormonal therapy approved in the US for the treatment of breast cancer in adjuvant and metastatic settings. ... Ad-Hoc-News - Ad-Hoc-News (Pressemitteilung)

DOJ Tells Supreme Court to Reject Reverse-Payment Case  -  May 31, 2007
The plaintiffs alleged that the companies' patent settlement over AstraZeneca's breast cancer drug Nolvadex (tamoxifen citrate) was anticompetitive. ... FDA news - FDA news (subscription)

Cytogen Announces Schedule for Clinical Data Presentations at …  -  May 25, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... Free with registration - PR Newswire - AccessMyLibrary.com

Press Release: Cytogen to Raise $10.1 Million through Private...  -  Jul 2, 2007
...a PSMA-targeting monoclonal antibody-based agent to image the extent and spread of prostate cancer and SOLTAMOXâ„¢ (tamoxifen citrate) is the first liquid ... FierceBiotech

Cytogen Corporation (CYTO) CEO and Mayor Rudy Giuliani to Ring the …  -  Aug 31, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... primezone.com

Cytogen to Present at Upcoming Investor Conferences in September.( …  -  Aug 28, 2007
...(tamoxifen citrate) is the first liquid hormonal therapy approved in the US for the treatment of breast cancer in adjuvant and metastatic settings. ... Free with registration - Business Wire - AccessMyLibrary.com

Cytogen to Release Second-Quarter 2006 Earnings and Host Conference …  -  Jul 25, 2006
PROSTASCINT(R) (capromab pendetide) kit for the preparation of Indium In-111 capromab pendetide, and SOLTAMOX(TM) (tamoxifen citrate, oral solution ... Free with registration - PR Newswire - AccessMyLibrary.com

Brand Names/Synonyms:
tamoxifen citrate is also known by the following brand names and/or synonyms,Citrate; Apo-Tamox; CCRIS 3275; CTX; Citofen; Crisafeno; Diemon; Gen-Tamoxifen; HSDB 6782; Istubol; Kessar; Noltam; Nolvadex; Nolvadex-D; Nourytam; Novo-Tamoxifen; Oncomox; Pms-Tamoxifen; Retaxim; TRANS FORM OF TAMOXIFEN; Tamizam; Tamofen; Tamone; Tamoxasta; Tamoxen; Tamoxifen; Tamoxifen Citrate; Tamoxifen Drug Standard Solution; Tamoxifen and Its Salts; Tamoxifene [Inn-French]; Tamoxifeno [Inn-Spanish]; Tamoxifenum [Inn-Latin]; Trans-Tamoxifen; Valodex; Zemide

Drug Category:
tamoxifen citrate is categorized under the following by the FDA: Antineoplastic Agents; ATC:L02BA01

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
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Chemical IUPAC Name:
[5-(2-amino-6-oxo-3,9-dihydropurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-[(3,4-dihydroxy-6-methyl-5-oxo-tetrahydropyran-2-yl)oxy-hydroxy-phosphoryl]oxy-phosphinicacid





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