tegaserod maleate

This page contains recent news articles, when available, and an overview of tegaserod maleate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

tegaserod maleate
(when available)

Pharmacology and use:
Tegaserod is indicated for the short-term treatment of women with irritable bowel syndrome (IBS) whose primary bowel symptom is constipation. Irritable bowel syndrome with constipation and chronic idiopathic constipation are both lower gastrointestinal dysmotility disorders. Clinical investigations have shown that both motor and sensory functions of the gut appear to be altered in patients suffering from irritable bowel syndrome (IBS), while in patients with chronic idiopathic constipation, reduced intestinal motility is the predominant cause of the condition. Both the enteric nervous system, which acts to integrate and process information in the gut, and 5-hydroxytryptamine (5-HT, serotonin) are thought to represent key elements in the etiology of both IBS and idiopathic constipation. Approximately 95% of serotonin is found throughout the gastrointestinal tract, primarily stored in enterochromaffin cells but also in enteric nerves acting as a neurotransmitter. Serotonin has been shown to be involved in regulating motility, visceral sensitivity and intestinal secretion. Investigations suggest an important role of serotonin Type-4 (5-HT4) receptors in the maintenance of gastrointestinal functions in humans. 5-HT4 receptor mRNA has been found throughout the human gastrointestinal tract. Provides relief from the symptoms of irritable bowel syndrome including chronic idiopathic constipation.

Mechanism Of Action:
Tegaserod is a 5-HT4 receptor partial agonist that binds with high affinity at human 5-HT4 receptors, whereas it has no appreciable affinity for 5-HT3 or dopamine receptors. It has moderate affinity for 5-HT1 receptors. Tegaserod, by acting as an agonist at neuronal 5-HT4 receptors, triggers the release of further neurotransmitters such as calcitonin gene-related peptide from sensory neurons. The activation of 5-HT4 receptors in the gastrointestinal tract stimulates the peristaltic reflex and intestinal secretion, as well as inhibits visceral sensitivity.

News Articles on Tegaserod

Alert Center: Tegaserod Maleate: Public Health Advisory  -  Mar 30, 2007
On March 30, 2007, Novartis, in compliance with an FDA request, suspended marketing and sales of its irritable bowel/constipation drug tegaserod maleate ... Medscape

New Data for Tegaserod maleate Demonstrate Relief of Multiple …  -  Oct 24, 2006
LAS VEGAS, NV -- October 24, 2006 -- Zelnorm (tegaserod maleate) has demonstrated potential to treat the multiple symptoms of dysmotility-type dyspepsia, ... DG News

Tegaserod Maleate Restricted to Emergency Use Only  -  Apr 4, 2008
April 4, 2008 — Tegaserod maleate (Zelnorm; Novartis) will only be available for emergency situations that are immediately life-threatening or serious ... Medscape

Press Release: Novartis suspends US marketing and sales of Zelnorm(R)...  -  Apr 2, 2007
Novartis markets the therapy under the trademark Zelnorm (tegaserod maleate) in the US, Canada, Philippines and South Africa; and as Zelmac (tegaserod) in ... FierceBiotech

Novartis drug roll-back may plague Cipla, Emcure  -  Apr 6, 2007
The NPAC is yet to take a view on tegaserod maleate. NPAC sources said that the panel is not yet aware of the US developments. ... Business Standard

Press Release: Results Show Promise for Zelnorm in the Treatment of …  -  May 18, 2005
A new health economic study for Zelnorm(R) (tegaserod maleate) shows a significant ... Pharmacology & Therapeutics demonstrate Zelnorm (tegaserod maleate) ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Significant increased risk of heart attack and stroke ...  -  Nov 3, 2008
A new health economic study for Zelnorm(R) (tegaserod maleate) shows a significant ... Pharmacology & Therapeutics demonstrate Zelnorm (tegaserod maleate) ... Pay-Per-View - PR Newswire - HighBeam Research

Zelnorm Linked to Increased CV Events  -  Mar 30, 2007
It also noted that no effect of tegaserod maleate on the coronary arteries was seen in preclinical and clinical testing. Quoted in a company press release ... Medscape

Press Release: Zelnorm(R) to be Made Available to US Patients Under …  -  Jul 27, 2007
A new health economic study for Zelnorm(R) (tegaserod maleate) shows a significant ... Pharmacology & Therapeutics demonstrate Zelnorm (tegaserod maleate) ... Pay-Per-View - PR Newswire - HighBeam Research

Press Release: Study Reveals Zelnorm(R) May Be a Safe and Effective …  -  May 22, 2006
LOS ANGELES, May 22 /PRNewswire/ -- Novartis today announced study results showing promise for Zelnorm(R) (tegaserod maleate) as a safe and efficacious ... Pay-Per-View - PR Newswire - HighBeam Research

Irritable Bowel Syndrome (IBS)  -  Dec 16, 2005
Tegaserod maleate (Zelnorm®) is approved for women with IBS who have constipation as their main symptom. There aren't any conclusive diagnostic tests for ... WSOCtv.com

Article: FDA to allow tegaserod use in certain patients.(Gastroenterol...  -  Aug 15, 2007
IBS The Novartis drug Zelnorm(TM) (tegaserod maleate ... Drug Administration (FDA) for the short-term ... Medicine in Dallas. "Zelnorm is an important ... Pay-Per-View - Internal Medicine News - HighBeam Research

New Zelnorm® Data Demonstrate Relief Of Multiple Symptoms Of …  -  Nov 3, 2006
The gastrointestinal medicine Zelnorm® (tegaserod maleate) has demonstrated potential benefits in helping patients with the multiple symptoms of a common ... Medical News Today - Medical News Today (press release)

FDA Announces Restricted Access Program for Zelnorm  -  Jul 27, 2007
July 27, 2007 — Restricted use of tegaserod maleate (Zelnorm, ... Although tegaserod maleate was suspended from the US market in March, when a safety ... Medscape

Press Release: FDA Permits Restricted Use of Zelnorm for Qualifying …  -  Jul 27, 2007
The U.S. Food and Drug Administration announced that it is permitting the restricted use of Zelnorm (tegaserod maleate) under a treatment investigational ... Pay-Per-View - M2 Presswire - HighBeam Research

Article: Unsafe IBS drugs back on the market.(Prescription for...  -  Sep 1, 2007
FDA Consumer; July 1, 2004 ; 610 words ... ... taking or prescribing Zelnorm (tegaserod maleate ... FDA has revised the drug's labeling to include ... for ... Pay-Per-View - Women's Health Activist - HighBeam Research

Zelnorm effective against common dsypepsia.  -  Oct 30, 2006
Swiss drug major Novartis says that its gastrointestinal medicine Zelnorm (tegaserod maleate) demonstrated potential benefits in helping patients with the ... $9.94 - Pharma Marketletter - Alacra Store

St. Paul Pioneer Press (MN)  -  Mar 31, 2007
Zelnorm, also called tegaserod maleate, is a prescription medication approved for short-term treatment of women with irritable bowel syndrome with ... $2.95 - St. Paul Pioneer Press - NewsBank

Study Reveals Zelnorm(R) May Be A Safe And Effective Treatment For …  -  May 23, 2006
Novartis today announced study results showing promise for Zelnorm(R) (tegaserod maleate) as a safe and efficacious medical treatment for patients with ... Medical News Today - Medical News Today (press release)

FDA CAPSULES  -  Aug 7, 2007
The U.S. Food and Drug Administration is permitting the restricted use of Zelnorm (tegaserod maleate) under an investigational protocol to treat irritable ... Pay-Per-View - Newsday - ProQuest Archiver

Article: Tegaserod for IBS in women.(CLINICAL CAPSULES)(Brief...  -  Dec 15, 2005
Formulary; September 1, 2002 ; 700+ words ... ... constipationpredominant irritable bowel syndrome Abstract Tegaserod maleate (Zelnorm), an aminoguanidine ... Pay-Per-View - Internal Medicine News - HighBeam Research

Implants and suicide link  -  Aug 22, 2008
In compliance with an US-FDA request, Novartis has suspended marketing and sales of its irritable bowel/constipation drug Zelnorm (tegaserod maleate) which ... News Today Online

Novartis Committed To Making Zelnorm(R) Available For Women With …  -  Dec 17, 2005
...including the United States, Canada and Mexico. Novartis markets Zelnorm (tegaserod maleate) in the US, Canada, Philippines and South Africa; and under the. Medical News Today - Medical News Today (press release)

Pilot Study on the Effect of Linaclotide in Patients With Chronic …  -  Jan 9, 2008
Tegaserod maleate (marketed as Zelnorm) March 30, 2007. Amitiza (lubiprostone) Prescribing Information. Sucampo Pharmaceuticals Inc. February, 2006. ... Nature.com

New Developments in the Treatment of Constipation: Editor's Note  -  Jan 11, 2005
On March 30, 2007, Novartis, in compliance with an FDA request, suspended marketing and sales of its irritable bowel/constipation drug tegaserod maleate ... Medscape

Tegaserod for Female Patients Suffering From IBS With Mixed Bowel …  -  Mar 8, 2007
...announced itwould comply with a request from the Food and Drug Administration (FDA) to suspend US marketing and sales of tegaserod maleate (Zelnorm). ... Nature.com

Does Sex Make a Difference?  -  Jul 19, 2005
For example, Zelnorm (tegaserod maleate) is approved only for women to relieve the symptoms of IBS. In clinical trials, more women taking Zelnorm reported ... RedOrbit

Novartis' Zelnorm "safe and efficacious" in IBS.  -  May 29, 2006
Swiss drug major Novartis says that new study results, which show its serotonin receptor antagonist Zelnorm (tegaserod maleate) is a "safe and efficacious" ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

US drug DTC cuts in 1st-half 2008: TV ad effectiveness low, regulatory...  -  Oct 27, 2008
...and Schering-Plough, respectively, and Zelnorm (tegaserod maleate), an irritable-bowel-syndrome treatment from Swiss pharmaceutical major Novartis. ... $9.94 - Pharma Marketletter - Alacra Store

Zelnorm® May Be Safe and Effective for Some IBS Patients With Mixed …  -  Jun 8, 2006
LOS ANGELES -- Novartis announced study results showing promise for Zelnorm® (tegaserod maleate) as a safe and efficacious medical treatment for patients ... EndoNurse

Relief for Constipation; 'Zelnorm Works By Increasing the Contraction...  -  Nov 3, 2005
The drug, Zelnorm (tegaserod maleate) is the first and only FDA- approved medicine for the treatment of chronic constipation that lasts for more than six ... RedOrbit

Article: Constipation Drug Pulled Upon FDA's Request - The Washington...  -  Mar 31, 2007
Zelnorm, also called tegaserod maleate, is a prescription medication approved for the short-term treatment of women with irritable bowel syndrome, ... Pay-Per-View - Washington Post - HighBeam Research

Novartis' 4th-qtr profits fall 45%; but full-year 2007 income climbs...  -  Jan 21, 2008
...given the withdrawal of the bowel disease drug Zelnorm (tegaserod maleate; Marketletter August 6, 2007) and the impact of generic competition for key ... $9.94 - Pharma Marketletter - Alacra Store

Zelnorm[R].(POSTSCRIPTS)(Brief article)  -  Mar 22, 2006
ZELNORM[R] (tegaserod maleate, Novartis) is a prescription medication that the FDA had approved in 2002 for the short-term treatment of women with irritable ... Free with registration - Nutrition Health Review - AccessMyLibrary.com

Novartis breaks ground on Singapore facility  -  Mar 8, 2005
...pressure drug Diovan (valsartan) and cancer treatment Glivec (imatinib), as well as its irritable bowel symdrome treatment Zelnorm (tegaserod maleate). ... In-PharmaTechnologist.com

Two drugs withdrawn at FDA behest  -  Mar 30, 2007
Tegaserod maleate (Zelnorm) and pergolide (Permax and generics) have been withdrawn from the market for safety concerns. Tagaserod had been approved for ... Cortlandt Forum

Competitors by Product Report  -  Mar 29, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere Reports - Revere

Antibiotic proves promising  -  Jan 4, 2006
Researchers are now testing the use of another drug, tegaserod maleate, can help prevent overgrowth of bacteria for longer periods of time. WOWT

Antidepressants often better than bulking agents for IBS.(News)(irrita...  -  May 1, 2005
In clinical trials, tegaserod maleate (Zelnorm) was effective in about 40% of patients. Yet about 30% of placebo patients had improvement, as they often do ... Free with registration - Internal Medicine News - AccessMyLibrary.com

US Public Citizen "told you so" about Zelnorm.(Brief article)  -  Apr 9, 2007
Drug Administration in 2001, of Switzerland-based drug major Novartis' constipation-predominant diarrhea drug Zelnorm (tegaserod maleate; see page 3). ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

Extensive work-up rarely needed to diagnose IBS.(Gastroenterology)( …  -  Dec 15, 2008
...at an international ... welcome, given the scarcity of approved agents for irritable bowel syndrome (IBS), particularly since tegaserod maleate ... ... Pay-Per-View - Internal Medicine News - HighBeam Research

Delayed Gastric Emptying Doesn't Affect Quality of Life Dyspeptic...  -  Nov 17, 2006
On March 30, 2007, Novartis, in compliance with an FDA request, suspended marketing and sales of its irritable bowel/constipation drug tegaserod maleate ... Medscape

Non-GI symptoms can help differentiate bowel disorders.(Clinical...  -  Dec 1, 2005
They should have read, "Tegaserod maleate (Zelnorm), approved in 2002, is indicated for IBS patients with constipation. Alosetron hydrochloride (Lotronex) ... Pay-Per-View - OB GYN News - HighBeam Research

Suspended – sale of drug to treat IBS  -  Apr 3, 2007
The medication Zelmac (tegaserod maleate), which is marketed in the United States under the brand name Zelnorm, has been found by the Food and Drug ... Malaysia Star

Competitors by Product Report  -  Mar 1, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere Reports - Revere

Irritable Bowel Syndrome: New and Emerging Therapies  -  Mar 3, 2006
On March 30, 2007, Novartis, in compliance with an FDA request, suspended marketing and sales of its irritable bowel/constipation drug tegaserod maleate ... Medscape

national/new jerey state briefs  -  Mar 31, 2007
Zelnorm, also called tegaserod maleate, is a prescription medication approved for short-term treatment of women with irritable bowel syndrome with ... $2.95 - Press of Atlantic City, The - NewsBank

DTC effectiveness doubted as drugmakers are accused of exploiting …  -  Sep 8, 2008
...majors Wyeth and Schering-Plough, respectively, and Zelnorm (tegaserod maleate), an irritable-bowel treatment from Swiss pharmaceutical major Novartis. ... $9.94 - Pharma Marketletter - Alacra Store

tegaserod Novartis submitted for approval, Europe (irritable bowel …  -  Feb 7, 2005
...tegaserod, tegaserod maleate, HTF 919, SDZ HTF919, SDZ-HTF 919, ZELMAC, ZELNORM, IRBEZ, TAGON, TAGESPA, TEGIBS, TEGASER, IBSINORM, TIBS-6, TEGASPA, A3G, ... Pay-Per-View - R & D Focus Drug News - Factiva, from Dow Jones

Review Article: Intestinal Serotonin Signalling in IBS: Editor's Note  -  Apr 13, 2006
On March 30, 2007, Novartis, in compliance with an FDA request, suspended marketing and sales of its irritable bowel/constipation drug tegaserod maleate ... Medscape

Company agrees to halt sales of constipation drug  -  Mar 31, 2007
Novartis agreed to withdraw Zelnorm, also called tegaserod maleate, at the FDA's request, the agency said in a public-health advisory. Pay-Per-View - Orlando Sentinel - ProQuest Archiver

BRIEFS  -  Mar 31, 2007
Also called tegaserod maleate, the prescription medication is approved for short-term treatment of women with irritable bowel syndrome with constipation and ... Pay-Per-View - Newsday - ProQuest Archiver

Competitors by Product Report  -  Jun 21, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere - Alacra Store

AbelsonTaylor Expands DTC Capabilities.  -  Nov 27, 2006
...of the most successful Rx consumer launches in history, including the Gold Effie Award-winning campaign for Zelnorm (tegaserod maleate) from Novartis. ... Free with registration - PR Newswire - AccessMyLibrary.com

Irritable Bowel Syndrome; Study of pro-motility agent shows improved ...  -  Jan 24, 2005
2005 JAN 24 - (NewsRx.com & NewsRx.net) -- A new health economic study for Zelnorm (tegaserod maleate) shows a significant improvement in overall work ... Pay-Per-View - Health & Medicine Week - Factiva, from Dow Jones

Competitors by Product Report  -  Jun 21, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere Reports - Revere

Millions Live With Painful GI Symptoms Impacting Their Lives, But …  -  Oct 5, 2006
Novartis Pharmaceuticals Corporation, manufacturer of Zelnorm(R) (tegaserod maleate), is the exclusive sponsor of the ABCs of GI Relief Health Center at ... Medical News Today - Medical News Today (press release)

Irritable Bowel Syndrome; Study of pro-motility agent shows improved ...  -  Jan 25, 2005
2005 JAN 25 - (NewsRx.com & NewsRx.net) -- A new health economic study for Zelnorm (tegaserod maleate) shows a significant improvement in overall work ... Pay-Per-View - Science Letter - Factiva, from Dow Jones

Competitors by Product Report  -  Jun 21, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere Reports - Revere

Restricted Zelnorm Use Permitted  -  Jul 31, 2007
The FDA is permitting restricted Zelnorm (tegaserod maleate) use under investigational new drug (IND) protocol to treat irritable bowel syndrome with ... Facts and Comparisons

News in brief - April 23/30, 2007  -  Apr 23, 2007
At the request of the Food and Drug Administration, Novartis Pharmaceuticals has stopped marketing Zelnorm (tegaserod maleate) because of an increased risk ... American Medical News

Zelnorm pulled off the shelf due to possible cardiovascular risk...  -  Apr 15, 2007
Novartis has agreed tO withdraw its irritable bowel syndrome drug Zelnorm (tegaserod maleate) from the US market in response to a Food and Drug ... Free with registration - Family Practice News - AccessMyLibrary.com

Life Science News Briefs Vol. 7 no.5 — April 5 2007  -  Apr 5, 2007
Novartis Canada (Dorval) is complying with a request from Health Canada to suspend Canadian marketing and sales of Zelnorm(R)(1) (tegaserod maleate) as a ... ic.gc.ca

Novartis' sales up 17% to $7.2 B in 2006, with eight product launches...  -  Jan 29, 2007
Revenue gains were also made by: the breast cancer drug Femara (letrozole), up 33% to $719.0 million; Zelnorm/ Zelmac (tegaserod maleate) for the treatment ... Free with registration - Pharma Marketletter - AccessMyLibrary.com

AbelsonTaylor, the largest independent advertising agency in the …  -  Jan 1, 2007
...of the most successful Rx consumer launches in history, including the Gold Effie Award-winning campaign for Zelnorm (tegaserod maleate) from Novartis. ... Free with registration - Medical Marketing & Media - AccessMyLibrary.com

From the pharmacy.(MEDICAL MAILBOX)  -  Jul 1, 2007
IBS Drug Pulled From Shelves: The makers of Zelnorm (tegaserod maleate) have voluntarily discontinued sales of this drug. The reason: concerns over serious ... Free with registration - Saturday Evening Post - AccessMyLibrary.com

Lawyers Seek FDA Zelnorm Documents through Freedom of Information …  -  Feb 20, 2007
USC 552) seeking documents and records as they pertain to the Novartis Pharmaceuticals Corporation's drug Zelnorm (tegaserod maleate). ... prleap.com

Commercial interruptions: The hidden costs of drug ads  -  Apr 2, 2007
Kurt Stange, MD, PhD, professor of family medicine at Case Western Reserve University in Cleveland, found a Novartis ad for Zelnorm (tegaserod maleate), ... American Medical News

MANAGE IBS WITHOUT SPECIAL DRUGS  -  Jun 28, 2007
Earlier this year, the Food and Drug Administration asked the company that makes tegaserod maleate (Zelnorm) to remove the drug from the market. ... $2.95 - Myrtle Beach Sun News - NewsBank

Does sex make a difference?  -  Jul 1, 2005
For example, Zelnorm (tegaserod maleate) is approved only for women to relieve the symptoms of IBS. In clinical trials, more women taking Zelnorm reported ... $4.95 - FDA Consumer - ECNext

Vaccines and diagnostics help Swiss major Novartis beat expectations.  -  Apr 28, 2008
...competition for four products and the marketing suspension of its bowel disease therapy Zelnorm (tegaserod maleate; Marketletter August 6, 2007). ... $9.94 - Pharma Marketletter - Alacra Store

Salix Pharmaceuticals Reports American College of Gastroenterology …  -  Oct 24, 2006
Patients had failed numerous therapies including PEG solution, tegaserod maleate and lactulose. Patients were treated with 1 (n=1), 2 (n=1) or 3 (n=7) ... Free with registration - Business Wire - AccessMyLibrary.com

Press of Atlantic City, The (NJ)  -  Jul 28, 2007
The agency said it asked Swiss pharmaceutical maker Novartis AG in March to suspend sales of the prescription drug, also called tegaserod maleate, ... $2.95 - Press of Atlantic City, The - NewsBank

Factiva Search  -  Jan 24, 2005
2005 JAN 24 - (NewsRx.com & NewsRx.net) -- A new health economic study for Zelnorm (tegaserod maleate) shows a significant ... ... Pay-Per-View - Managed Care Weekly Digest - Factiva, from Dow Jones

Competitors by Product Report  -  Jun 21, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere - Alacra Store

Rias A/S acquires Nordisk Plast A/S - Deal Snapshot - AlacraStore.com  -  Mar 3, 2008
Modulator) Zelnorm (Tegaserod Maleate) Novo Nordisk A/S (ADR) ( NVO ) Products: NovoSeven (Recombinant…Low Dose Paroxetine Mesylate) Novo Nordisk A/S (ADR) ... Pay-Per-View - deals - Alacra Store

AbelsonTaylor, the largest independent advertising agency in the …  -  Jan 1, 2007
...of the most successful Rx consumer launches in history, including the Gold Effie Award-winning campaign for Zelnorm (tegaserod maleate) from Novartis. ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

CBT promising for treatment of irritable bowel syndrome.( …  -  Feb 15, 2008
Internal Medicine News; July 1, 2007 ; 700+ words ... ... approved agents for irritable bowel syndrome (IBS), particularly since tegaserod maleate ... said. ... Pay-Per-View - Internal Medicine News - HighBeam Research

Competitors by Product Report  -  Jan 12, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere Reports - Revere

Avoid bulking agents in diarrhea-predominant IBS.(Clinical Rounds)  -  May 15, 2005
In clinical trials, tegaserod maleate (Zelnorm) was effective in about 40% of patients. Yet, about 30% of placebo patients had improvement, as they often do ... Pay-Per-View - OB GYN News - Factiva, from Dow Jones

Factiva Search  -  Jan 24, 2005
2005 JAN 24 - (NewsRx.com & NewsRx.net) -- A new health economic study for Zelnorm (tegaserod maleate) shows a significant ... ... Pay-Per-View - Biotech Business Week - Factiva, from Dow Jones

Antidepressants show promise for IBS treatment.(Gastroenterology)( …  -  Aug 15, 2008
Internal Medicine News; July 1, 2007 ; 700+ words ... ... approved agents for irritable bowel syndrome (IBS), particularly since tegaserod maleate ... said. ... Pay-Per-View - Internal Medicine News - HighBeam Research

Irritable Bowel Syndrome; Study of pro-motility agent shows improved ...  -  Jan 28, 2005
2005 JAN 28 - (NewsRx.com & NewsRx.net) -- A new health economic study for Zelnorm (tegaserod maleate) shows a significant improvement in overall work ... Pay-Per-View - Drug Week - Factiva, from Dow Jones

A spokesperson for the Food and Drug.(POSTSCRIPTS)(Brief article) | …  -  Dec 22, 2005
ZELNORM[R] (tegaserod maleate, Novartis) is a prescription medication that the F.D.A. had approved in 2002 for the short-term treatment of women with ... Pay-Per-View - Nutrition Health Review - HighBeam Research

Article: IBS drug pipeline offers some promise.(Gastroenterology)(Irri...  -  Jul 1, 2007
New drugs would be welcome, given the scarcity of approved agents for irritable bowel syndrome (IBS), particularly since tegaserod maleate (Zelnorm) was ... Pay-Per-View - Internal Medicine News - HighBeam Research

Competitors by Product Report  -  Dec 13, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere Reports - Revere

Sales Halted for Constipation Drug | Article from AP Online |...  -  Mar 30, 2007
Zelnorm, also called tegaserod maleate, is a prescription medication approved for short-term treatment of women with irritable bowel syndrome with ... Pay-Per-View - Associated Press/AP Online - HighBeam Research

Harvard Women's Health Watch May , 2005  -  May 1, 2005
A. Zelnorm (tegaserod maleate) is a prescription medication for the short-term treatment of women with irritable bowel syndrome (IBS) whose primary symptom ... $4.95 - Harvard Women's Health Watch - ECNext

Zelnorm's potential for GI disorders revealed.(GastroIntestinal)  -  May 30, 2005
...which took place in Chicago, Illinois, USA, indicate that Novartis' irritable bowel syndrome drug Zelnorm (tegaserod maleate) may offer a novel approach ... $4.95 - Pharma Marketletter - ECNext

Dot-whacked.(Viewpoint) | Article from Medical Marketing & Media | …  -  May 1, 2007
Medical Marketing & Media; January 1, 2007 ; 700+ words ... ... campaign for Zelnorm (tegaserod maleate) from Novartis. He was also responsible for the ... Pay-Per-View - Medical Marketing & Media - HighBeam Research

Two nutritional scientists.(POSTSCRIPTS)(Brief article) | Article...  -  Dec 22, 2005
ZELNORM[R] (tegaserod maleate, Novartis) is a prescription medication that the F.D.A. had approved in 2002 for the short-term treatment of women with ... Pay-Per-View - Nutrition Health Review - HighBeam Research

Zelnorm pulled off the shelf due to possible cardiovascular risk...  -  Apr 15, 2007
FDA) ... find Family Practice News articles. Novartis has agreed tO withdraw its irritable bowel syndrome drug Zelnorm (tegaserod maleate) from the US m... Pay-Per-View - Family Practice News - HighBeam Research

Press Release: AbelsonTaylor Expands DTC Capabilities. - PR Newswire …  -  Nov 27, 2006
...of the most successful Rx consumer launches in history, including the Gold Effie Award-winning campaign for Zelnorm (tegaserod maleate) from Novartis. ... Pay-Per-View - PR Newswire - HighBeam Research

Competitors by Product Report  -  Oct 11, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere Reports - Revere

IBS drug pipeline offers some promise to patients.(Clinical Rounds)  -  Jul 1, 2007
New drugs would be welcome, given the scarcity of approved agents for irritable bowel syndrome (IBS), particularly since tegaserod maleate (Zelnorm) was ... $4.95 - Skin & Allergy News - ECNext

Competitors by Product Report  -  Dec 13, 2008
Novartis AG (ADR) (NVS) Products:. AKU517; Idenix Valtorcitabine/LDC300; NIM811 (Cyclophilin Binding HCV RdRP Modulator); Zelnorm (Tegaserod Maleate) ... $75.00 - Revere - Alacra Store

Alizyme updates on Ph III R&D program in preparation for a busy...  -  Oct 15, 2007
The firm said that, since the withdrawal of Novartis' former market leading IBS medication Zelnorm (tegaserod maleate; Marketletter August 6), ... $4.95 - Pharma Marketletter - ECNext

Narcotic bowel syndrome requires withdrawal.(Gastroenterology) |...  -  Jan 1, 2008
...symposium ... welcome, given the scarcity of approved agents for irritable bowel syndrome (IBS), particularly since tegaserod maleate (Zelnorm ... ... Pay-Per-View - Internal Medicine News - HighBeam Research

Zelnorm, pergolide off the market.(In Other News)  -  Jun 1, 2007
At the FDA's request, the manufacturers of the irritable bowel syndrome treatment Zelnorm (tegaserod maleate) and the Parkinson's disease drug pergolide ... $4.95 - Pharmaceutical Representative - ECNext

Axcan Pharma appoints new Senior Vice President and Chief Scientific ...  -  May 10, 2006
While at Novartis, Dr. LeBeaut served as a project leader on major research programs, including the development of Zelnorm(R) (tegaserod maleate), ... $4.95 - PR Newswire - ECNext

Brand Names/Synonyms:
tegaserod maleate is also known by the following brand names and/or synonymsHTF 919; SDZ HTF 919; Tegaserod; Tegaserod Maleate; Tegaserod [Usan:Inn:Ban]; Zelmac; Zelnorm

Drug Category:
tegaserod maleate is categorized under the following by the FDA: Gastrointestinal Agents; ATC:A03AE02

Dosage Forms:
TABLET

Absorption:
Rapidly absorbed after oral administration. Absolute bioavailability is approximately 10%.

Interactions:
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Chemical IUPAC Name:
[3-[(amino-pentylimino-methyl)aminoiminomethyl]-1H-indol-5-yl]methanol





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